Caspase-11 Mediates Inflammatory Dopaminergic Cell Death in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson's Disease

Journal of Neuroscience

Volumn 24, Issue 8, 2004, Pages 1865-1872

  Furuya, Tsuyoshi ^a   Hayakawa, Hideki ^a   Yamada, Masanori ^a   Yoshimi, Kenji ^a   Hisahara, Shin ^b   Miura, Masayuki ^c,d   Mizuno, Yoshikuni ^a   Mochizuki, Hideki ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SAPPORO MEDICAL UNIVERSITY   (Japan)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

Apoptosis; Caspase 1; Caspase 11; Inflammation; MPTP; Parkinson's disease

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 3,4 DIHYDROXYPHENYLACETIC ACID; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 11; DOPAMINE; FREE RADICAL; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; RNA;

ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; DOPAMINERGIC NERVE CELL; GENE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MOUSE; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; APOPTOSIS; CASPASES; CELL COUNT; DISEASE MODELS, ANIMAL; DOPAMINE; ENZYME INHIBITORS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; INTERLEUKIN-1; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NEOSTRIATUM; NEURONS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PARKINSONIAN DISORDERS; SUBSTANTIA NIGRA; TIME FACTORS; UP-REGULATION;

EID: 1442275733     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3309-03.2004     Document Type: Article

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