Lysosomal storage diseases and the heat shock response: Convergences and therapeutic opportunities

Journal of Lipid Research

Volumn 55, Issue 11, 2014, Pages 2198-2210

  Ingemann, Linda ^a   Kirkegaard, Thomas ^a  

^a ORPHAZYME A S   (Denmark)

Author keywords

Glycosphingolipids; Heat shock proteins; Molecular chaperones; Sphingolipids; Stress response

Indexed keywords

ARIMOCLOMOL; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CALCIUM CHANNEL BLOCKING AGENT; CELASTROL; CHAPERONE; GLUCOSYLCERAMIDASE; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HEAT SHOCK TRANSCRIPTION FACTOR 1; HISTONE DEACETYLASE INHIBITOR; PROTEASOME INHIBITOR; PSYCHOSINE; REACTIVE OXYGEN METABOLITE; CALCIUM;

AMYOTROPHIC LATERAL SCLEROSIS; AUTOPHAGY; CALCIUM HOMEOSTASIS; CELL DEATH; CELL PROTECTION; DEGENERATIVE DISEASE; ENDOPLASMIC RETICULUM STRESS; ENZYME REPLACEMENT; GAUCHER DISEASE; HEAT SHOCK RESPONSE; HUMAN; INCLUSION BODY MYOSITIS; LYSOSOME; LYSOSOME MEMBRANE; LYSOSOME MEMBRANE PERMEABILIZATION; LYSOSOME STORAGE DISEASE; MEMBRANE BIOLOGY; METABOLIC STRESS; MISSENSE MUTATION; MUCOLIPIDOSIS TYPE 1; NIEMANN PICK DISEASE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN HOMEOSTASIS; PROTEIN MISFOLDING; REVIEW; UNFOLDED PROTEIN RESPONSE; ANIMAL; HOMEOSTASIS; INTRACELLULAR MEMBRANE; LYSOSOMAL STORAGE DISEASES; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; CALCIUM; CELL DEATH; HEAT-SHOCK RESPONSE; HOMEOSTASIS; HUMANS; INTRACELLULAR MEMBRANES; LYSOSOMAL STORAGE DISEASES;

EID: 84929513267     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.R048090     Document Type: Review

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