Altered cholesterol metabolism in Niemann-Pick type C1 mouse brains affects mitochondrial function

Journal of Biological Chemistry

Volumn 280, Issue 12, 2005, Pages 11731-11739

  Yu, Wenxin ^a   Gong, Jian Sheng ^a,b   Ko, Mihee ^a   Garver, William S ^c   Yanagisawa, Katsuhiko ^a   Michikawa, Makoto ^a  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^b PHARMACEUTICALS AND MEDICAL DEVICES AGENCY   (Japan)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; CHOLESTEROL; GENES; METABOLISM; NEUROLOGY;

MITOCHONDRIA; NEURODEGENERATION; NEURONAL DYSFUNCTION; NIEMANN-PICK TYPE C1 (NPC1) DISEASE;

DISEASES;

ADENOSINE TRIPHOSPHATE; CHOLESTEROL; METHYL BETA CYCLODEXTRIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ANIMAL CELL; ARTICLE; BRAIN; CELL CULTURE; CELL FUNCTION; CHOLESTEROL METABOLISM; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ANALYSIS; GENETIC DISORDER; IMMUNOBLOTTING; LIPID ANALYSIS; MITOCHONDRION; MOUSE; NERVE CELL; NERVE DEGENERATION; NERVE FIBER GROWTH; NIEMANN PICK DISEASE; NONHUMAN; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

ADENOSINE TRIPHOSPHATE; ANIMALS; ASTROCYTES; BRAIN; CELLS, CULTURED; CHOLESTEROL; MEMBRANE POTENTIALS; MICE; MICE, INBRED BALB C; MITOCHONDRIA; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; NIEMANN-PICK DISEASES; PHOSPHOLIPIDS; PROTEINS;

EID: 15744378799     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412898200     Document Type: Article

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