Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice

American Journal of Pathology

Volumn 175, Issue 6, 2009, Pages 2540-2556

  Amritraj, Asha ^a   Peake, Kyle ^a   Kodam, Anitha ^a   Salio, Chiara ^b   Merighi, Adalberto ^b   Vance, Jean E ^a   Kar, Satyabrata ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA (2 DIETHYLAMINOETHOXY)ANDROST 5 EN 17 ONE; CATHEPSIN B; CATHEPSIN D; CHOLESTEROL; CYTOCHROME C; LYSOSOME ENZYME; PROTEIN BAX; PROTEIN BAX 2; SOMATOMEDIN B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CELL; CELL FRACTIONATION; CELL VIABILITY; CELLULAR DISTRIBUTION; CEREBELLUM; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME INHIBITION; HIPPOCAMPUS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIPID ANALYSIS; MOUSE; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NIEMANN PICK DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 73549105909     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2009.081096     Document Type: Article

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