Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1/apolipoprotein A-I pathway: 1-Phenyl-2-decanoylamino-3-morpholino-1- propanol is a novel cholesterol efflux accelerator

Journal of Biological Chemistry

Volumn 280, Issue 26, 2005, Pages 24515-24523

  Glaros, Elias N ^a   Kim, Woojin Scott ^a   Quinn, Carmel M ^a   Wong, Jenny ^a   Gelissen, Ingrid ^a   Jessup, Wendy ^a   Garner, Brett ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHOLESTEROL; CYTOLOGY; GENETIC ENGINEERING; HEMODYNAMICS; PROTEINS;

CHOLESTEROL ACCUMULATION; GLYCOSPHINGOLIPID; INTRACELLULAR CHOLESTEROL; PROTEIN EXPRESSION;

LIPIDS;

2 DECANOYLAMINO 3 MORPHOLINO 1 PHENYL 1 PROPANOL; ABC TRANSPORTER A1; APOLIPOPROTEIN A1; CHOLESTEROL; CONDURITOL B EPOXIDE; GLUCOSYLCERAMIDASE; GLYCOPHOSPHOLIPID; HYDROLASE INHIBITOR; LACTOSYLCERAMIDE; MESSENGER RNA; MIGLUSTAT; UNCLASSIFIED DRUG;

ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DOSE RESPONSE; FABRY DISEASE; FIBROBLAST; FOAM CELL; GENE EXPRESSION; GM1 GANGLIOSIDOSIS; HOMEOSTASIS; HUMAN; HUMAN CELL; LIPID STORAGE; LIPIDOSIS; LIPOGENESIS; MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SANDHOFF DISEASE;

1-DEOXYNOJIRIMYCIN; ANTIGENS, CD; APOLIPOPROTEIN A-I; ATP-BINDING CASSETTE TRANSPORTERS; BIOTINYLATION; BLOTTING, WESTERN; CELL LINE; CELL MEMBRANE; CHOLESTEROL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FIBROBLASTS; GLYCOSPHINGOLIPIDS; HUMANS; LACTOSYLCERAMIDES; LIPOPROTEINS, LDL; MONOCYTES; MORPHOLINES; PHOSPHOLIPIDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; UP-REGULATION;

EID: 21644474053     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413862200     Document Type: Article

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