Intralysosomal iron chelation protects against oxidative stress-induced cellular damage

FEBS Journal

Volumn 273, Issue 13, 2006, Pages 3106-3117

  Kurz, Tino ^a   Gustafsson, Bertil ^b   Brunk, Ulf T ^a,b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cell death; Lysosomes; Mitochondria; Redox active iron; Salicylaldehyde isonicotinoyl hydrazone

Indexed keywords

DEFEROXAMINE; IRON CHELATING AGENT; LIPID; SALICYLALDEHYDE ISONICOTINOYL HYDRAZONE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COMPARTMENTALIZATION; CELL CULTURE; CELL DAMAGE; CELL DEATH; CELL DISRUPTION; CELL PROTECTION; CELL SURVIVAL; CELL TRANSPORT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOCYTOSIS; INCUBATION TIME; IRON CHELATION; IRON STORAGE; LIPID SOLUBILITY; LYSOSOME MEMBRANE; MITOCHONDRIAL MEMBRANE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL;

ALDEHYDES; APOPTOSIS; CELL PROLIFERATION; CHELATING AGENTS; DEFEROXAMINE; ENDOCYTOSIS; HYDRAZONES; HYDROGEN PEROXIDE; IRON; IRON CHELATING AGENTS; LYSOSOMES; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; NECROSIS; OXIDANTS; OXIDATIVE STRESS;

EID: 33745205646     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05321.x     Document Type: Article

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