Sensitivity to Lysosome-Dependent Cell Death Is Directly Regulated by Lysosomal Cholesterol Content

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Appelqvist, Hanna ^a   Sandin, Linnea ^a   Björnström, Karin ^a,b   Saftig, Paul ^c   Garner, Brett ^d   Öllinger, Karin ^a,b   Kågedal, Katarina ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

^b Centre of Surgery and Oncology   (Sweden)

^c UNIVERSITY OF KIEL   (Germany)

^d UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYCHOLESTEROL; 3BETA (2 DIETHYLAMINOETHOXY)ANDROST 5 EN 17 ONE; CARRIER PROTEIN; CHOLESTEROL; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; MEPACRINE; METHYL BETA CYCLODEXTRIN; MUTANT PROTEIN; NPC1 PROTEIN; THERMOZYMOCIDIN; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; FIBROBLAST; HUMAN; HUMAN CELL; LIPID STORAGE; LYSOSOME; LYSOSOME MEMBRANE; MEMBRANE PERMEABILITY; MEMBRANE STABILIZATION; NERVE CELL; OXIDATIVE STRESS;

ANDROSTENES; BETA-CYCLODEXTRINS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL DEATH; CHOLESTEROL; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; HYDROXYCHOLESTEROLS; IMMUNOHISTOCHEMISTRY; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; MEMBRANE GLYCOPROTEINS; MICROSCOPY, PHASE-CONTRAST; MUTATION; NEURONS; QUINACRINE; STATISTICS, NONPARAMETRIC;

EID: 84869223682     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050262     Document Type: Article

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