GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis

Molecular Cell

Volumn 15, Issue 5, 2004, Pages 753-766

  Tessitore, Alessandra ^a   Martin, Maria Del P ^a   Sano, Renata ^a   Ma, Yanjun ^a   Mann, Linda ^a   Ingrassia, Angela ^a   Laywell, Eric D ^b   Steindler, Dennis A ^b   Hendershot, Linda M ^a   D'Azzo, Alessandra ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CALCIUM; CASPASE 12; CCAAT ENHANCER BINDING PROTEIN; GANGLIOSIDE GM1; GLUCOSE REGULATED PROTEIN 78; STRESS ACTIVATED PROTEIN KINASE; CASP12 PROTEIN, MOUSE; CASPASE; CHAPERONE; DDIT3 PROTEIN, MOUSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 9; MOLECULAR CHAPERONE GRP78; N ACETYLGALACTOSAMINYLTRANSFERASE; POLYPEPTIDE N ACETYLGALACTOSAMINYLTRANSFERASE; POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE; TRANSCRIPTION FACTOR;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ACTIVATION; GANGLIOSIDOSIS; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; PHENOTYPE; PROTEIN FOLDING; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE; ANIMAL; CELL CULTURE; CELL DEATH; DISEASE MODEL; GENETICS; GM1 GANGLIOSIDOSIS; METABOLISM; MOUSE MUTANT; NERVE CELL; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALIA;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BETA-GALACTOSIDASE; CALCIUM; CASPASE 12; CASPASES; CCAAT-ENHANCER-BINDING PROTEINS; CELL DEATH; CELLS, CULTURED; DISEASE MODELS, ANIMAL; G(M1) GANGLIOSIDE; GANGLIOSIDOSIS, GM1; HEAT-SHOCK PROTEINS; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR CHAPERONES; N-ACETYLGALACTOSAMINYLTRANSFERASES; NERVE DEGENERATION; NEURONS; PROTEIN FOLDING; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS;

EID: 4444355320     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2004.08.029     Document Type: Article

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