Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion

Journal of Experimental Medicine

Volumn 197, Issue 10, 2003, Pages 1323-1334

  Boya, Patricia ^a   Andreau, Karine ^a   Poncet, Delphine ^a   Zamzami, Naoufal ^a   Perfettini, Jean Luc ^a   Metivier, Didier ^a   Ojcius, David M ^b   Jäättelä, Marja ^c   Kroemer, Guido ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b INSTITUT PASTEUR   (France)

^c DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

Author keywords

Apoptosis; Autophagy; Bax; Bcl 2; Caspases

Indexed keywords

CASPASE; CATHEPSIN; CIPROFLOXACIN; CYTOCHROME C; NORFLOXACIN; PHOSPHATIDYLSERINE; PROTEIN BAK; PROTEIN BAX; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL LOSS; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LYSOSOME; LYSOSOME MEMBRANE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; ULTRAVIOLET RADIATION;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CELL MEMBRANE PERMEABILITY; CIPROFLOXACIN; HELA CELLS; HUMANS; LYSOSOMES; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; MITOCHONDRIA; NORFLOXACIN; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES;

EID: 0038529617     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021952     Document Type: Article

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