-
1
-
-
0035942309
-
Enzymes of sphingolipid metabolism: from modular to integrative signaling
-
Y.A. Hannun C. Luberto K.M. Argraves Enzymes of sphingolipid metabolism: from modular to integrative signaling Biochemistry 40 2001 4893 4903
-
(2001)
Biochemistry
, vol.40
, pp. 4893-4903
-
-
Hannun, Y.A.1
Luberto, C.2
Argraves, K.M.3
-
2
-
-
0037680229
-
Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism
-
K. Hanada Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism Biochim. Biophys. Acta 1632 2003 16 30
-
(2003)
Biochim. Biophys. Acta
, vol.1632
, pp. 16-30
-
-
Hanada, K.1
-
4
-
-
33845336495
-
Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy
-
W. Zheng J. Kollmeyer H. Symolon A. Momin E. Munter E. Wang S. Kelly J.C. Allegood Y. Liu Q. Peng H. Ramaraju M.C. Sullards M. Cabot A.H. Merrill Jr. Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy Biochim. Biophys. Acta 1758 2006 1864 1884
-
(2006)
Biochim. Biophys. Acta
, vol.1758
, pp. 1864-1884
-
-
Zheng, W.1
Kollmeyer, J.2
Symolon, H.3
Momin, A.4
Munter, E.5
Wang, E.6
Kelly, S.7
Allegood, J.C.8
Liu, Y.9
Peng, Q.10
Ramaraju, H.11
Sullards, M.C.12
Cabot, M.13
Merrill, A.H.14
-
6
-
-
34548604943
-
Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization
-
Z. Li T.K. Hailemariam H. Zhou Y. Li D.C. Duckworth D.A. Peake Y. Zhang M.S. Kuo G. Cao X.C. Jiang Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization Biochim. Biophys. Acta 1771 2007 1186 1194
-
(2007)
Biochim. Biophys. Acta
, vol.1771
, pp. 1186-1194
-
-
Li, Z.1
Hailemariam, T.K.2
Zhou, H.3
Li, Y.4
Duckworth, D.C.5
Peake, D.A.6
Zhang, Y.7
Kuo, M.S.8
Cao, G.9
Jiang, X.C.10
-
7
-
-
34547110137
-
Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells
-
F.G. Tafesse K. Huitema M. Hermansson S. van der Poel J. van den Dikkenberg A. Uphoff P. Somerharju J.C. Holthuis Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells J. Biol. Chem. 282 2007 17537 17547
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 17537-17547
-
-
Tafesse, F.G.1
Huitema, K.2
Hermansson, M.3
van der Poel, S.4
van den Dikkenberg, J.5
Uphoff, A.6
Somerharju, P.7
Holthuis, J.C.8
-
8
-
-
38949191625
-
SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis
-
T. Ding Z. Li T. Hailemariam S. Mukherjee F.R. Maxfield M.P. Wu X.C. Jiang SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis J. Lipid. Res. 49 2008 376 385
-
(2008)
J. Lipid. Res.
, vol.49
, pp. 376-385
-
-
Ding, T.1
Li, Z.2
Hailemariam, T.3
Mukherjee, S.4
Maxfield, F.R.5
Wu, M.P.6
Jiang, X.C.7
-
9
-
-
33846526677
-
Resistance to alkyl-lysophospholipid-induced apoptosis due to downregulated sphingomyelin synthase 1 expression with consequent sphingomyelin- and cholesterol-deficiency in lipid rafts
-
A.H. Van der Luit M. Budde S. Zerp W. Caan J.B. Klarenbeek M. Verheij W.J. Van Blitterswijk Resistance to alkyl-lysophospholipid-induced apoptosis due to downregulated sphingomyelin synthase 1 expression with consequent sphingomyelin- and cholesterol-deficiency in lipid rafts Biochem. J. 401 2007 541 549
-
(2007)
Biochem. J.
, vol.401
, pp. 541-549
-
-
Van der Luit, A.H.1
Budde, M.2
Zerp, S.3
Caan, W.4
Klarenbeek, J.B.5
Verheij, M.6
Van Blitterswijk, W.J.7
-
13
-
-
35348846777
-
Photodynamic therapy with the phthalocyanine photosensitizer Pc 4: the case experience with preclinical mechanistic and early clinical-translational studies
-
J.D. Miller E.D. Baron H. Scull A. Hsia J.C. Berlin T. McCormick V. Colussi M.E. Kenney K.D. Cooper N.L. Oleinick Photodynamic therapy with the phthalocyanine photosensitizer Pc 4: the case experience with preclinical mechanistic and early clinical-translational studies Toxicol. Appl. Pharmacol. 224 2007 290 299
-
(2007)
Toxicol. Appl. Pharmacol.
, vol.224
, pp. 290-299
-
-
Miller, J.D.1
Baron, E.D.2
Scull, H.3
Hsia, A.4
Berlin, J.C.5
McCormick, T.6
Colussi, V.7
Kenney, M.E.8
Cooper, K.D.9
Oleinick, N.L.10
-
15
-
-
0043065270
-
Reactive oxygen species generation is independent of de novo sphingolipids in apoptotic photosensitized cells
-
V. Dolgachev B. Nagy B. Taffe K. Hanada D. Separovic Reactive oxygen species generation is independent of de novo sphingolipids in apoptotic photosensitized cells Exp. Cell Res. 288 2003 425 436
-
(2003)
Exp. Cell Res.
, vol.288
, pp. 425-436
-
-
Dolgachev, V.1
Nagy, B.2
Taffe, B.3
Hanada, K.4
Separovic, D.5
-
16
-
-
2542501763
-
De novo ceramide accumulation due to inhibition of its conversion to complex sphingolipids in apoptotic photosensitized cells
-
V. Dolgachev M.S. Farooqui O.I. Kulaeva M.A. Tainsky B. Nagy K. Hanada D. Separovic De novo ceramide accumulation due to inhibition of its conversion to complex sphingolipids in apoptotic photosensitized cells J. Biol. Chem. 279 2004 23238 23249
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 23238-23249
-
-
Dolgachev, V.1
Farooqui, M.S.2
Kulaeva, O.I.3
Tainsky, M.A.4
Nagy, B.5
Hanada, K.6
Separovic, D.7
-
17
-
-
34248216667
-
Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage
-
D. Separovic K. Hanada M.Y. Maitah B. Nagy I. Hang M.A. Tainsky J.M. Kraniak J. Bielawski Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage Biochem. Biophys. Res. Commun. 358 2007 196 202
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.358
, pp. 196-202
-
-
Separovic, D.1
Hanada, K.2
Maitah, M.Y.3
Nagy, B.4
Hang, I.5
Tainsky, M.A.6
Kraniak, J.M.7
Bielawski, J.8
-
18
-
-
33746271951
-
Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry
-
J. Bielawski Z.M. Szulc Y.A. Hannun A. Bielawska Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry Methods 39 2006 82 91
-
(2006)
Methods
, vol.39
, pp. 82-91
-
-
Bielawski, J.1
Szulc, Z.M.2
Hannun, Y.A.3
Bielawska, A.4
-
19
-
-
0025323167
-
Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus
-
A.H. Futerman B. Stieger A.L. Hubbard R.E. Pagano Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus J. Biol. Chem. 265 1990 8650 8657
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 8650-8657
-
-
Futerman, A.H.1
Stieger, B.2
Hubbard, A.L.3
Pagano, R.E.4
-
20
-
-
0035863069
-
Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans
-
C. Luberto D.L. Toffaletti E.A. Wills S.C. Tucker A. Casadevall J.R. Perfect Y.A. Hannun M. Del Poeta Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans Genes Dev. 15 2001 201 212
-
(2001)
Genes Dev.
, vol.15
, pp. 201-212
-
-
Luberto, C.1
Toffaletti, D.L.2
Wills, E.A.3
Tucker, S.C.4
Casadevall, A.5
Perfect, J.R.6
Hannun, Y.A.7
Del Poeta, M.8
-
21
-
-
0004269485
-
Statistical Models in S
-
J.M. Chambers T.J. Hastie Statistical Models in S 1992 Wadsworth & Brooks/Cole, Pacific Grove
-
(1992)
-
-
Chambers, J.M.1
Hastie, T.J.2
-
22
-
-
0001677717
-
Controlling the false discovery rate: a practical and powerful approach to multiple testing
-
Y. Benjamini Y. Hochberg Controlling the false discovery rate: a practical and powerful approach to multiple testing J. Royal Stat. Soc., B 57 1995 289 300
-
(1995)
J. Royal Stat. Soc., B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
24
-
-
0034641918
-
The biochemistry of apoptosis
-
M.O. Hengartner The biochemistry of apoptosis Nature 407 2000 770 776
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
25
-
-
0034733910
-
Sphingosine-1-phosphate: signaling inside and out
-
S. Spiegel S. Milstien Sphingosine-1-phosphate: signaling inside and out FEBS Lett. 476 2000 55 57
-
(2000)
FEBS Lett.
, vol.476
, pp. 55-57
-
-
Spiegel, S.1
Milstien, S.2
-
26
-
-
0038352072
-
BcR-induced apoptosis involves differential regulation of C16 and C24-ceramide formation and sphingolipid-dependent activation of the proteasome
-
B.J. Kroesen S. Jacobs B.J. Pettus H. Sietsma J.W. Kok Y.A. Hannun L.F. de Leij BcR-induced apoptosis involves differential regulation of C16 and C24-ceramide formation and sphingolipid-dependent activation of the proteasome J. Biol. Chem. 278 2003 14723 14731
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14723-14731
-
-
Kroesen, B.J.1
Jacobs, S.2
Pettus, B.J.3
Sietsma, H.4
Kok, J.W.5
Hannun, Y.A.6
de Leij, L.F.7
-
27
-
-
0034661482
-
Sphingosine 1-phosphate signalling in mammalian cells
-
S. Pyne N.J. Pyne Sphingosine 1-phosphate signalling in mammalian cells Biochem. J. 349 2000 385 402
-
(2000)
Biochem. J.
, vol.349
, pp. 385-402
-
-
Pyne, S.1
Pyne, N.J.2
-
28
-
-
0035861589
-
Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells. Reactive oxygen species and mitochondrial inner membrane permeabilization
-
M. Lam N.L. Oleinick A.L. Nieminen Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells. Reactive oxygen species and mitochondrial inner membrane permeabilization J. Biol. Chem. 276 2001 47379 47386
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47379-47386
-
-
Lam, M.1
Oleinick, N.L.2
Nieminen, A.L.3
-
29
-
-
0026149993
-
The photodegradation of porphyrins in cells can be used to estimate the lifetime of singlet oxygen
-
J. Moan K. Berg The photodegradation of porphyrins in cells can be used to estimate the lifetime of singlet oxygen Photochem. Photobiol. 53 1991 549 553
-
(1991)
Photochem. Photobiol.
, vol.53
, pp. 549-553
-
-
Moan, J.1
Berg, K.2
-
30
-
-
0022143647
-
Interdependence of fluence, drug dose and oxygen on hematoporphyrin derivative induced photosensitization of tumor mitochondria
-
S.L. Gibson R. Hilf Interdependence of fluence, drug dose and oxygen on hematoporphyrin derivative induced photosensitization of tumor mitochondria Photochem. Photobiol. 42 1985 367 373
-
(1985)
Photochem. Photobiol.
, vol.42
, pp. 367-373
-
-
Gibson, S.L.1
R. Hilf2
-
31
-
-
0028448460
-
The use of tetrazolium salts to determine sites of damage to the mitochondrial electron transport chain in intact cells following in vitro photodynamic therapy with Photofrin II
-
D.A. Musser A.R. Oseroff The use of tetrazolium salts to determine sites of damage to the mitochondrial electron transport chain in intact cells following in vitro photodynamic therapy with Photofrin II Photochem. Photobiol. 59 1994 621 626
-
(1994)
Photochem. Photobiol.
, vol.59
, pp. 621-626
-
-
Musser, D.A.1
Oseroff, A.R.2
-
32
-
-
0033599307
-
Photodynamic therapy-induced apoptosis in lymphoma cells: translocation of cytochrome c causes inhibition of respiration as well as caspase activation
-
M.E. Varnes S.M. Chiu L.Y. Xue N.L. Oleinick Photodynamic therapy-induced apoptosis in lymphoma cells: translocation of cytochrome c causes inhibition of respiration as well as caspase activation Biochem. Biophys. Res. Commun. 255 1999 673 679
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.255
, pp. 673-679
-
-
Varnes, M.E.1
Chiu, S.M.2
Xue, L.Y.3
Oleinick, N.L.4
-
34
-
-
0037458619
-
Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol
-
D. Han F. Antunes R. Canali D. Rettori E. Cadenas Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol J. Biol. Chem. 278 2003 5557 5563
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5557-5563
-
-
Han, D.1
Antunes, F.2
Canali, R.3
Rettori, D.4
Cadenas, E.5
-
35
-
-
0023109281
-
Sidedness of ceramide-phosphoethanolamine synthesis on rat liver and brain microsomal membranes
-
M. Malgat A. Maurice J. Baraud Sidedness of ceramide-phosphoethanolamine synthesis on rat liver and brain microsomal membranes J. Lipid Res. 28 1987 138 143
-
(1987)
J. Lipid Res.
, vol.28
, pp. 138-143
-
-
Malgat, M.1
Maurice, A.2
Baraud, J.3
-
36
-
-
12244284610
-
Possible role of ceramide as an indicator of chemoresistance: decrease of the ceramide content via activation of glucosylceramide synthase and sphingomyelin synthase in chemoresistant leukemia
-
M. Itoh T. Kitano M. Watanabe T. Kondo T. Yabu Y. Taguchi K. Iwai M. Tashima T. Uchiyama T. Okazaki Possible role of ceramide as an indicator of chemoresistance: decrease of the ceramide content via activation of glucosylceramide synthase and sphingomyelin synthase in chemoresistant leukemia Clin. Cancer Res. 9 2003 415 423
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 415-423
-
-
Itoh, M.1
Kitano, T.2
Watanabe, M.3
Kondo, T.4
Yabu, T.5
Taguchi, Y.6
Iwai, K.7
Tashima, M.8
Uchiyama, T.9
Okazaki, T.10
-
37
-
-
33745883535
-
Identification of mouse sphingomyelin synthase 1 as a suppressor of Bax-mediated cell death in yeast
-
Z. Yang C. Khoury G. Jean-Baptiste M.T. Greenwood Identification of mouse sphingomyelin synthase 1 as a suppressor of Bax-mediated cell death in yeast FEMS Yeast Res. 6 2006 751 762
-
(2006)
FEMS Yeast Res.
, vol.6
, pp. 751-762
-
-
Yang, Z.1
Khoury, C.2
Jean-Baptiste, G.3
Greenwood, M.T.4
|