Role of endogenous psychosine accumulation in oligodendrocyte differentiation and survival: Implication for Krabbe disease

Brain Research

Volumn 1508, Issue , 2013, Pages 44-52

  Won, Je Seong ^a   Kim, Jinsu ^a   Paintlia, Manjeet Kaur ^a   Singh, Inderjit ^a   Singh, Avtar K ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

Differentiation; Krabbe disease; Myelin; Oligodendrocyte; Peroxisome; Psychosine

Indexed keywords

7,7 DIMETHYLEICOSADIENOIC ACID; CERAMIDE GALACTOSYLTRANSFERASE; GALACTOSYL SPHINGOLIPID; GALACTOSYLCERAMIDASE; GALACTOSYLCERAMIDE; ICOSANOID; LIPID; MYELIN; PSYCHOSINE; SECRETORY PHOSPHOLIPASE A2; SPHINGOLIPID; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GALACTOSE;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL MATURATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME SYNTHESIS; GALACTOSYLATION; GENE SILENCING; GLOBOID CELL LEUKODYSTROPHY; HUMAN; HUMAN CELL; NONHUMAN; OLIGODENDROGLIA; PATHOLOGY; PRIORITY JOURNAL; RAT; RNA INTERFERENCE;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL SURVIVAL; FLUORESCENT ANTIBODY TECHNIQUE; GALACTOSYLCERAMIDASE; GALACTOSYLCERAMIDES; HUMANS; IN SITU NICK-END LABELING; LEUKODYSTROPHY, GLOBOID CELL; LIPID METABOLISM; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MYELIN SHEATH; OLIGODENDROGLIA; PSYCHOSINE; RATS; REAL-TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSFECTION;

EID: 84876113312     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.02.024     Document Type: Article

References (31)

1. N. Baumann, and D. Pham-Dinh Biology of oligodendrocyte and myelin in the mammalian central nervous system Physiol. Rev. 81 2001 871 927 (Pubitemid 32267079)
2. J. Bielawski, Z.M. Szulc, Y.A. Hannun, and A. Bielawska Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry Methods 39 2006 82 91 (Pubitemid 44107706)
3. W.W. Cleland, and E.P. Kennedy The enzymatic synthesis of psychosine J. Biol. Chem. 235 1960 45 51
4. M.A. Contreras, and S.I. Rapoport Recent studies on interactions between n-3 and n-6 polyunsaturated fatty acids in brain and other tissues Curr. Opin. Lipidol. 13 2002 267 272 (Pubitemid 34592283)
5. M.A. Contreras, E. Haq, T. Uto, I. Singh, and A.K. Singh Psychosine-induced alterations in peroxisomes of twitcher mouse liver Arch. Biochem. Biophys. 477 2008 211 218
6. S. Giri, M. Jatana, R. Rattan, J.S. Won, I. Singh, and A.K. Singh Galactosylsphingosine (psychosine)-induced expression of cytokine-mediated inducible nitric oxide synthases via AP-1 and C/EBP: implications for Krabbe disease FASEB J. 16 2002 661 672 (Pubitemid 34465430)
7. 2 in oligodendrocyte cell death J. Lipid Res. 47 2006 1478 1492 (Pubitemid 44079902)
8. A.K. Hajra, and A.K. Das Lipid biosynthesis in peroxisomes Ann. NY Acad. Sci. 804 1996 129 141 (Pubitemid 27056607)
9. S.M. Hall The effect of injections of lysophosphatidyl choline into white matter of the adult mouse spinal cord J. Cell Sci. 10 1972 535 546
10. E. Haq, S. Giri, I. Singh, and A.K. Singh Molecular mechanism of psychosine-induced cell death in human oligodendrocyte cell line J. Neurochem. 86 2003 1428 1440 (Pubitemid 37174259)
11. E. Haq, M.A. Contreras, S. Giri, I. Singh, and A.K. Singh Dysfunction of peroxisomes in twitcher mice brain: a possible mechanism of psychosine-induced disease Biochem. Biophys. Res. Commun. 343 2006 229 238
12. M. Jatana, S. Giri, and A.K. Singh Apoptotic positive cells in Krabbe brain and induction of apoptosis in rat C6 glial cells by psychosine Neurosci. Lett. 330 2002 183 187 (Pubitemid 35257895)
13. M. Khan, E. Haq, S. Giri, I. Singh, and A.K. Singh Peroxisomal participation in psychosine-mediated toxicity: implications for Krabbe's disease J. Neurosci. Res. 80 2005 845 854 (Pubitemid 40961296)
14. T. Kobayashi, N. Shinnoh, I. Goto, and Y. Kuroiwa Hydrolysis of galactosylceramide is catalyzed by two genetically distinct acid beta-galactosidases J. Biol. Chem. 260 1985 14982 14987 (Pubitemid 16188361)
15. W.J. Kovacs, L.M. Olivier, and S.K. Krisans Central role of peroxisomes in isoprenoid biosynthesis Prog. Lipid Res. 41 2002 369 391 (Pubitemid 34712036)
16. W.J. Kovacs, and S. Krisans Cholesterol biosynthesis and regulation: role of peroxisomes Adv. Exp. Med. Biol. 544 2003 315 327 (Pubitemid 38326587)
17. K. Mitsuo, T. Kobayashi, N. Shinnoh, and I. Goto Biosynthesis of galactosylsphingosine (psychosine) in the twitcher mouse Neurochem. Res. 14 1989 899 903 (Pubitemid 19274846)
18. T. Miyatake, and K. Suzuki Globoid cell leukodystrophy: additional deficiency of psychosine galactosidase Biochem. Biophys. Res. Commun. 48 1972 539 543
19. A.S. Paintlia, M.K. Paintlia, A.K. Singh, J.K. Orak, and I. Singh Activation of PPAR-gamma and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells Glia 58 2010 1669 1685
20. Y. Pang, B. Zheng, L.W. Fan, P.G. Rhodes, and Z. Cai IGF-1 protects oligodendrocyte progenitors against TNFalpha-induced damage by activation of PI3K/Akt and interruption of the mitochondrial apoptotic pathway Glia 55 2007 1099 1107 (Pubitemid 47204202)
21. M. Schrader, and H.D. Fahimi Peroxisomes and oxidative stress Biochim. Biophys. Acta 1763 2006 1755 1766 (Pubitemid 44880480)
22. S. Schulte, and W. Stoffel Ceramide UDPgalactosyltransferase from myelinating rat brain: purification, cloning, and expression Proc. Natl. Acad. Sci. USA 90 1993 10265 10269 (Pubitemid 23328293)
23. H. Sprecher Metabolism of highly unsaturated n-3 and n-6 fatty acids Biochim. Biophys. Acta 1486 2000 219 231 (Pubitemid 30618862)
24. K. Suzuki Twenty five years of the 'psychosine hypothesis': a personal perspective of its history and present status Neurochem. Res. 23 1998 251 259
25. K. Suzuki Globoid cell leukodystrophy (Krabbe's disease): update J. Child Neurol. 18 2003 595 603 (Pubitemid 37258464)
26. L. Svennerholm, M.T. Vanier, and J.E. Mansson Krabbe disease: a galactosylsphingosine (psychosine) lipidosis J. Lipid Res. 21 1980 53 64 (Pubitemid 10120438)
27. M.T. Vanier, and L. Svennerholm Chemical pathology of Krabbe disease: the occurrence of psychosine and other neutral sphingoglycolipids Adv. Exp. Med. Biol. 68 1976 115 126
28. M.T. Vanier, and L. Svennerholm Chemical pathology of Krabbe's disease. III. Ceramide-hexosides and gangliosides of brain Acta Paediatr. Scand. 64 1975 641 648
29. P.D. Whitfield, P.C. Sharp, R. Taylor, and P. Meikle Quantification of galactosylsphingosine in the twitcher mouse using electrospray ionization-tandem mass spectrometry J. Lipid Res. 42 2001 2092 2095 (Pubitemid 34001059)
30. J.S. Won, Y.B. Im, L. Key, I. Singh, and A.K. Singh The involvement of glucose metabolism in the regulation of inducible nitric oxide synthase gene expression in glial cells: possible role of glucose-6-phosphate dehydrogenase and CCAAT/enhancing binding protein J. Neurosci. 23 2003 7470 7478 (Pubitemid 37034063)
31. M. Zaka, M.A. Rafi, H.Z. Rao, P. Luzi, and D.A. Wenger Insulin-like growth factor-1 provides protection against psychosine-induced apoptosis in cultured mouse oligodendrocyte progenitor cells using primarily the PI3K/Akt pathway Mol. Cell Neurosci. 30 2005 398 407 (Pubitemid 41416557)