Evidence of lysosomal membrane permeabilization in mucopolysaccharidosis type I: Rupture of calcium and proton homeostasis

Journal of Cellular Physiology

Volumn 223, Issue 2, 2010, Pages 335-342

  Pereira, Vanessa Gonçalves ^a   Gazarini, Marcos L ^a   Rodrigues, Lara Cheliz ^a   Da Silva, Flávia Helena ^a,b   Han, Sang Won ^a   Martins, A M ^a   Tersariol, Ivarne L S ^a   D'Almeida, Vânia ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYSTEINE PROTEINASE; PROTON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL PH; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HURLER SYNDROME; LYSOSOME MEMBRANE; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTON TRANSPORT; SPLEEN CELL;

ANIMALS; APOPTOSIS; CALCIUM; CALCIUM SIGNALING; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; CYSTEINE PROTEASES; CYTOSOL; ENDOPLASMIC RETICULUM; HOMEOSTASIS; INTRACELLULAR MEMBRANES; LYSOSOMES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL; MUCOPOLYSACCHARIDOSIS I; PROTONS;

MURINAE; MUS;

EID: 77950839179     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22039     Document Type: Article

References (41)

1. Bach G, Chen CS, Pagano RE. 1999. Elevated lysosomal pH in mucolipidosis type IV cells. Clin Chim Acta 280:173-179. (Pubitemid 29094592)
2. Berridge MJ, Lipp P, Bootman MD. 2000. The versatility and universality of calcium signalling. Nat Rev Mol Cell Biol 1:11-21.
3. Berridge MJ, Bootman MD, Roderick HL. 2003. Calcium signalling: Dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 4:517-529.
4. Bootman MD, Berridge MJ, Roderick HL. 2002. Calcium signalling: more messengers, more channels, more complexity. Curr Biol 12:R563-R565.
5. Boya P, Kroemer G. 2008. Lysosomal membrane permeabilization in cell death. Oncogene 27:6434-6451.
6. Brunk UT, Svensson I. 1999. Oxidative stress, growth factor starvation and Fas activationmay all cause apoptosis through lysosomal leak. Redox Rep 4:3-11. (Pubitemid 29296774)
7. Cao Y, Espinola JA, Fossale E, Massey AC, Cuervo AM, MacDonald ME, Cotman SL. 2006. Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis. J Biol Chem 281:20483-20493. (Pubitemid 44065821)
8. Clarke LA, Russell CS, Pownall S, Warrington CL, Borowski A, Dimmick JE, Toone J, Jirik FR. 1997. Murine mucopolysaccharidosis type I: Targeted disruption of the murine alpha-Liduronidase gene. Hum Mol Genet 6:503-511. (Pubitemid 27142098)
9. Di Virgilio F, Steinberg TH, Silverstein SC. 1990. Inhibition of Fura-2 sequestration and secretion with organic anion transport blockers. Cell Calcium 11:57-62. (Pubitemid 20095531)
10. Ferri KF, Kroemer G. 2001. Organelle-specific initiation of cell death pathways. Nat Cell Biol 3:E255-E263. (Pubitemid 34428737)
11. Feske S. 2007. Calcium signalling in lymphocyte activation and disease. Nat Rev Immunol 7:690-702. (Pubitemid 47327393)
12. Fukuda T, Roberts A, Ahearn M, Zaal K, Ralston E, Plotz PH, Raben N. 2006. Autophagy and lysosomes in Pompe disease. Autophagy 2:318-320.
13. Futerman AH, van Meer G. 2004. The cell biology of lysosomal storage disorders. Nat Rev Mol Cell Biol 5:554-565. (Pubitemid 38868584)
14. Ginzburg L, Kacher Y, Futerman AH. 2004. The pathogenesis of glycosphingolipid storage disorders. Semin Cell Dev Biol 15:417-431.
15. Hayashi MA, Nascimento FD, Kerkis A, Oliveira V, Oliveira EB, Pereira A, Radis-Baptista G, Nader HB, Yamane T, Kerkis I, Tersariol IL. 2008. Cytotoxic effects of crotamine are mediated through lysosomal membrane permeabilization. Toxicon 52:508-517.
16. Itzhaki O, Skutelsky E, Kaptzan T, Sinai J, Michowitz M, Huszar M, Leibovici J. 2003. Ageingapoptosis relation in murine spleen. Mech Ageing Dev 124:999-1012.
17. Jennings JJ, Jr., Zhu JH, Rbaibi Y, Luo X, Chu CT, Kiselyov K. 2006. Mitochondrial aberrations in mucolipidosis type IV. J Biol Chem 281:39041-39050.
18. Jentsch TJ. 2007. Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters. J Physiol 578:633-640.
19. Jeyakumar M, Dwek RA, Butters TD, Platt FM. 2005. Storage solutions: Treating lysosomal disorders of the brain. Nat Rev Neurosci 6:713-725. (Pubitemid 44773245)
20. Khan YM, East JM, Lee AG. 1997. Effects of pH on phosphorylation of the Ca2+-ATPase of sarcoplasmic reticulum by inorganic phosphate. Biochem J 321:671-676. (Pubitemid 27084874)
21. Ko DC, Milenkovic L, Beier SM, Manuel H, Buchanan J, Scott MP. 2005. Cell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C disease. PLoS Genet 1:81-95.
22. Koike M, Shibata M, Waguri S, Yoshimura K, Tanida I, Kominami E, Gotow T, Peters C, von Figura K, Mizushima N, Saftig P, Uchiyama Y. 2005. Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease). Am J Pathol 167:1713-1728.
23. Korkotian E, Segal M. 1998. Fast confocal imaging of calcium released from stores in dendritic spines. Eur J Neurosci 10:2076-2084.
24. Lloyd-Evans E, Pelled D, Riebeling C, Bodennec J, de-Morgan A, Waller H, Schiffmann R, Futerman AH. 2003. Glucosylceramide and glucosylsphingosine modulate calcium mobilization from brain microsomes via different mechanisms. J Biol Chem 278:23594-23599.
25. Lloyd-Evans E, Morgan AJ, He X, Smith DA, Elliot-Smith E, Sillence DJ, Churchill GC, Schuchman EH, Galione A, Platt FM. 2008. Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium. Nat Med 14:1247-1255.
26. Luzio JP, Pryor PR, Bright NA. 2007. Lysosomes: Fusion and function. Nat Rev Mol Cell Biol 8:622-632.
27. Muenzer J, Wraith JE, Clarke LA. 2009. Mucopolysaccharidosis I: Management and treatment guidelines. Pediatrics 123:19-29.
28. Neufeld EF, Muenzer J. 2001. The mucopolysaccharidoses. In: Scriver C, Beaudet A, Sly WS, editors. The metabolic and molecular bases of inherited disease. New York: McGraw Hill. pp 3421-3452.
29. Ohmi K, Greenberg DS, Rajavel KS, Ryazantsev S, Li HH, Neufeld EF. 2003. Activated microglia in cortex of mouse models of mucopolysaccharidoses I and IIIB. Proc Natl Acad Sci USA 100:1902-1907.
30. Pastores GM, Arn P, Beck M, Clarke JT, Guffon N, Kaplan P, Muenzer J, Norato DY, Shapiro E, Thomas J, Viskochil D, Wraith JE. 2007. The MPS I registry: Design, methodology, and early findings of a global disease registry for monitoring patients with mucopolysaccharidosis type I. Mol Genet Metab 91:37-47.
31. Pelled D, Lloyd-Evans E, Riebeling C, Jeyakumar M, Platt FM, Futerman AH. 2003. Inhibition of calcium uptake via the sarco/endoplasmic reticulum Ca2+-ATPase in a mouse model of Sandhoff disease and prevention by treatment with N-butyldeoxynojirimycin. J Biol Chem 278:29496-29501.
32. Pryor PR, Mullock BM, Bright NA, Gray SR, Luzio JP. 2000. The role of intraorganellar Ca(2+) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organelles. J Cell Biol 149:1053-1062.
33. Robbins E, Marcus PI. 1963. Dynamics of acridine orange-cell interaction. I. interrelationships of acridine orange particles and cytoplasmic reddening. J Cell Biol 18:237-250.
34. Settembre C, Fraldi A, Jahreiss L, Spampanato C, Venturi C, Medina D, de Pablo R, Tacchetti C, Rubinsztein DC, Ballabio A. 2008. A block of autophagy in lysosomal storage disorders. Hum Mol Genet 17:119-129.
35. Stoka V, Turk B, Schendel SL, Kim TH, Cirman T, Snipas SJ, Ellerby LM, Bredesen D, Freeze H, Abrahamson M, Bromme D, Krajewski S, Reed JC, Yin XM, Turk V, Salvesen GS. 2001. Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route. J Biol Chem 276:3149-3157.
36. Stoka V, Turk B, Turk V. 2005. Lysosomal cysteine proteases: Structural features and their role in apoptosis. IUBMB Life 57:347-353.
37. Sumbilla C, Lu L, Lewis DE, Inesi G, Ishii T, Takeyasu K, Feng Y, Fambrough DM. 1993. Ca(2+)-dependent and thapsigargin-inhibited phosphorylation of Na+, K(+)-ATPase catalytic domain following chimeric recombination with Ca(2+)-ATPase. J Biol Chem 268:21185-21192.
38. Takamura A, Higaki K, Kajimaki K, Otsuka S, Ninomiya H, Matsuda J, Ohno K, Suzuki Y, Nanba E. 2008. Enhanced autophagy and mitochondrial aberrations in murine G(M1)-gangliosidosis. Biochem Biophys Res Commun 367:616-622.
39. Tanaka Y, Guhde G, Suter A, Eskelinen EL, Hartmann D, Lullmann-Rauch R, Janssen PM, Blanz J, von Figura K, Saftig P. 2000. Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice. Nature 406:902-906.
40. Turk B, Stoka V. 2007. Protease signalling in cell death: Caspases versus cysteine cathepsins. FEBS Lett 581:2761-2767.
41. Turk B, Turk D, Salvesen GS. 2002. Regulating cysteine protease activity: Essential role of protease inhibitors as guardians and regulators. Curr Pharm Des 8:1623-1637.