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Volumn 135, Issue 6, 2012, Pages 1724-1735

Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease

Author keywords

Gaucher's disease; lysosomal storage disorders; neuroinflammation

Indexed keywords

3 NITROTYROSINE; COLONY STIMULATING FACTOR 1; IBUPROFEN; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MINOCYCLINE; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR;

EID: 84861552789     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/aws095     Document Type: Article
Times cited : (123)

References (45)
  • 1
    • 70350689746 scopus 로고    scopus 로고
    • Biochemical and cellular toxicology of peroxynitrite: Implications in cell death and autoimmune phenomenon
    • Ahmad R, Rasheed Z, Ahsan H. Biochemical and cellular toxicology of peroxynitrite: implications in cell death and autoimmune phenomenon. Immunopharmacol Immunotoxicol 2009; 31: 388-96.
    • (2009) Immunopharmacol Immunotoxicol , vol.31 , pp. 388-396
    • Ahmad, R.1    Rasheed, Z.2    Ahsan, H.3
  • 2
    • 0033794577 scopus 로고    scopus 로고
    • Characterization of binding sites for chemo-kines MCP-1 and MIP-1alpha on human brain microvessels
    • Andjelkovic AV, Pachter JS. Characterization of binding sites for chemo-kines MCP-1 and MIP-1alpha on human brain microvessels. J Neurochem 2000; 75: 1898-906.
    • (2000) J Neurochem , vol.75 , pp. 1898-1906
    • Andjelkovic, A.V.1    Pachter, J.S.2
  • 3
    • 48449103907 scopus 로고    scopus 로고
    • Early neurodegeneration progresses independently of microglial activation by heparan sulfate in the brain of mucopolysaccharidosis IIIB mice
    • Ausseil J, Desmaris N, Bigou S, Attali R, Corbineau S, Vitry S, et al. Early neurodegeneration progresses independently of microglial activation by heparan sulfate in the brain of mucopolysaccharidosis IIIB mice. PLoS One 2008; 3: e2296.
    • (2008) PLoS One , vol.3
    • Ausseil, J.1    Desmaris, N.2    Bigou, S.3    Attali, R.4    Corbineau, S.5    Vitry, S.6
  • 5
    • 77957235446 scopus 로고    scopus 로고
    • Modeling neuroinflammatory pathogenesis of Parkinson's disease
    • Barnum CJ, Tansey MG. Modeling neuroinflammatory pathogenesis of Parkinson's disease. Prog Brain Res 2010; 184: 113-32.
    • (2010) Prog Brain Res , vol.184 , pp. 113-132
    • Barnum, C.J.1    Tansey, M.G.2
  • 6
    • 24144453087 scopus 로고    scopus 로고
    • Microglia and inflammation-mediated neurodegen-eration: Multiple triggers with a common mechanism
    • Block ML, Hong JS. Microglia and inflammation-mediated neurodegen-eration: multiple triggers with a common mechanism. Prog Neurobiol 2005; 76: 77-98.
    • (2005) Prog Neurobiol , vol.76 , pp. 77-98
    • Block, M.L.1    Hong, J.S.2
  • 7
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms
    • Block ML, Zecca L, Hong JS. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 2007; 8: 57-69.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.S.3
  • 8
    • 33745011334 scopus 로고    scopus 로고
    • Role of the pro-inflammatory cytokines TNF-alpha and IL-1beta in HIV-associated dementia
    • Brabers NA, Nottet HS. Role of the pro-inflammatory cytokines TNF-alpha and IL-1beta in HIV-associated dementia. Eur J Clin Invest 2006; 36: 447-58.
    • (2006) Eur J Clin Invest , vol.36 , pp. 447-458
    • Brabers, N.A.1    Nottet, H.S.2
  • 10
    • 64549159732 scopus 로고    scopus 로고
    • No evidence for activation of the unfolded protein response in neuronopathic models of Gaucher disease
    • Farfel-Becker T, Vitner E, Dekel H, Leshem N, Enquist IB, Karlsson S, et al. No evidence for activation of the unfolded protein response in neuronopathic models of Gaucher disease. Hum Mol Genet 2009; 18: 1482-8.
    • (2009) Hum Mol Genet , vol.18 , pp. 1482-1488
    • Farfel-Becker, T.1    Vitner, E.2    Dekel, H.3    Leshem, N.4    Enquist, I.B.5    Karlsson, S.6
  • 12
    • 79952607967 scopus 로고    scopus 로고
    • Spatial and temporal correlation between neuron loss and neuroinflammation in a mouse model of neuronopathic Gaucher disease
    • Farfel-Becker T, Vitner EB, Pressey SN, Eilam R, Cooper JD, Futerman AH. Spatial and temporal correlation between neuron loss and neuroinflammation in a mouse model of neuronopathic Gaucher disease. Hum Mol Genet 2011b; 20: 1375-86.
    • (2011) Hum Mol Genet , vol.20 , pp. 1375-1386
    • Farfel-Becker, T.1    Vitner, E.B.2    Pressey, S.N.3    Eilam, R.4    Cooper, J.D.5    Futerman, A.H.6
  • 14
    • 17944373768 scopus 로고    scopus 로고
    • Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex
    • Graus-Porta D, Blaess S, Senften M, Littlewood-Evans A, Damsky C, Huang Z, et al. Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex. Neuron 2001; 31: 367-79.
    • (2001) Neuron , vol.31 , pp. 367-379
    • Graus-Porta, D.1    Blaess, S.2    Senften, M.3    Littlewood-Evans, A.4    Damsky, C.5    Huang, Z.6
  • 16
    • 44949225039 scopus 로고    scopus 로고
    • Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia
    • Henry CJ, Huang Y, Wynne A, Hanke M, Himler J, Bailey MT, et al. Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia. J Neuroinflammation 2008; 5: 15.
    • (2008) J Neuroinflammation , vol.5 , pp. 15
    • Henry, C.J.1    Huang, Y.2    Wynne, A.3    Hanke, M.4    Himler, J.5    Bailey, M.T.6
  • 18
    • 33746868262 scopus 로고    scopus 로고
    • Upregulation of proinflammatory cytokines in the fetal brain of the Gaucher mouse
    • Hong YB, Kim EY, Jung SC. Upregulation of proinflammatory cytokines in the fetal brain of the Gaucher mouse. J Korean Med Sci 2006; 21: 733-8.
    • (2006) J Korean Med Sci , vol.21 , pp. 733-738
    • Hong, Y.B.1    Kim, E.Y.2    Jung, S.C.3
  • 19
  • 20
    • 0037378110 scopus 로고    scopus 로고
    • Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis
    • Jeyakumar M, Thomas R, Elliot-Smith E, Smith DA, van der Spoel AC, d'Azzo A, et al. Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis. Brain 2003; 126: 974-87.
    • (2003) Brain , vol.126 , pp. 974-987
    • Jeyakumar, M.1    Thomas, R.2    Elliot-Smith, E.3    Smith, D.A.4    Van Der Spoel, A.C.5    D'Azzo, A.6
  • 21
    • 17644422131 scopus 로고    scopus 로고
    • Gaucher disease: Pathological mechanisms and modern management
    • Jmoudiak M, Futerman AH. Gaucher disease: pathological mechanisms and modern management. Br J Haematol 2005; 129: 178-88.
    • (2005) Br J Haematol , vol.129 , pp. 178-188
    • Jmoudiak, M.1    Futerman, A.H.2
  • 23
    • 21244499298 scopus 로고    scopus 로고
    • TNF-related activation-induced cytokine enhances leukocyte adhesiveness: Induction of ICAM-1 and VCAM-1 via TNF receptor-associated factor and protein kinase C-dependent NF-kappaB activation in endo-thelial cells
    • Min JK, Kim YM, Kim SW, Kwon MC, Kong YY, Hwang IK, et al. TNF-related activation-induced cytokine enhances leukocyte adhesiveness: induction of ICAM-1 and VCAM-1 via TNF receptor-associated factor and protein kinase C-dependent NF-kappaB activation in endo-thelial cells. J Immunol 2005; 175: 531-40.
    • (2005) J Immunol , vol.175 , pp. 531-540
    • Min, J.K.1    Kim, Y.M.2    Kim, S.W.3    Kwon, M.C.4    Kong, Y.Y.5    Hwang, I.K.6
  • 25
    • 0034088326 scopus 로고    scopus 로고
    • The increased sensitivity of neurons with elevated glucocerebroside to neurotoxic agents can be reversed by imiglucerase
    • Pelled D, Shogomori H, Futerman AH. The increased sensitivity of neurons with elevated glucocerebroside to neurotoxic agents can be reversed by imiglucerase. J Inherit Metab Dis 2000; 23: 175-84.
    • (2000) J Inherit Metab Dis , vol.23 , pp. 175-184
    • Pelled, D.1    Shogomori, H.2    Futerman, A.H.3
  • 26
    • 70449525704 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors: Standing at the crossroads of immunobiology and neurobiology
    • Ransohoff RM. Chemokines and chemokine receptors: standing at the crossroads of immunobiology and neurobiology. Immunity 2009; 31: 711-21.
    • (2009) Immunity , vol.31 , pp. 711-721
    • Ransohoff, R.M.1
  • 28
    • 4744343655 scopus 로고    scopus 로고
    • Gaucher disease: Complexity in a "simple" disorder
    • Sidransky E. Gaucher disease: complexity in a "simple" disorder. Mol Genet Metab 2004; 83: 6-15.
    • (2004) Mol Genet Metab , vol.83 , pp. 6-15
    • Sidransky, E.1
  • 29
    • 70349767908 scopus 로고    scopus 로고
    • Beneficial effects of anti-inflammatory therapy in a mouse model of Niemann-Pick disease type C1
    • Smith D, Wallom KL, Williams IM, Jeyakumar M, Platt FM. Beneficial effects of anti-inflammatory therapy in a mouse model of Niemann-Pick disease type C1. Neurobiol Dis 2009; 36: 242-51.
    • (2009) Neurobiol Dis , vol.36 , pp. 242-251
    • Smith, D.1    Wallom, K.L.2    Williams, I.M.3    Jeyakumar, M.4    Platt, F.M.5
  • 32
    • 77950675049 scopus 로고    scopus 로고
    • Neuronopathic Gaucher disease in the mouse: Viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) mice with glucosylsphingosine and glucosylceramide accumulation and progressive neurological deficits
    • Sun Y, Liou B, Ran H, Skelton MR, Williams MT, Vorhees CV, et al. Neuronopathic Gaucher disease in the mouse: viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) mice with glucosylsphingosine and glucosylceramide accumulation and progressive neurological deficits. Hum Mol Genet 2010; 19: 1088-97.
    • (2010) Hum Mol Genet , vol.19 , pp. 1088-1097
    • Sun, Y.1    Liou, B.2    Ran, H.3    Skelton, M.R.4    Williams, M.T.5    Vorhees, C.V.6
  • 33
    • 79955404357 scopus 로고    scopus 로고
    • Isofagomine in vivo effects in a neuronopathic Gaucher disease mouse
    • Sun Y, Ran H, Liou B, Quinn B, Zamzow M, Zhang W, et al. Isofagomine in vivo effects in a neuronopathic Gaucher disease mouse. PLoS One 2011; 6: e19037.
    • (2011) PLoS One , vol.6
    • Sun, Y.1    Ran, H.2    Liou, B.3    Quinn, B.4    Zamzow, M.5    Zhang, W.6
  • 34
    • 34547673497 scopus 로고    scopus 로고
    • Peroxynitrite: Biochemistry, patho-physiology and development of therapeutics
    • Szabo C, Ischiropoulos H, Radi R. Peroxynitrite: biochemistry, patho-physiology and development of therapeutics. Nat Rev Drug Discov 2007; 6: 662-80.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 662-680
    • Szabo, C.1    Ischiropoulos, H.2    Radi, R.3
  • 35
    • 53049095216 scopus 로고    scopus 로고
    • TNF-alpha signaling in glaucomatous neurodegeneration
    • Tezel G. TNF-alpha signaling in glaucomatous neurodegeneration. Prog Brain Res 2008; 173: 409-21.
    • (2008) Prog Brain Res , vol.173 , pp. 409-421
    • Tezel, G.1
  • 37
    • 0035741488 scopus 로고    scopus 로고
    • Anti-inflammatory cytokines: Expression and action in the brain
    • Vitkovic L, Maeda S, Sternberg E. Anti-inflammatory cytokines: expression and action in the brain. Neuroimmunomodulation 2001; 9: 295-312.
    • (2001) Neuroimmunomodulation , vol.9 , pp. 295-312
    • Vitkovic, L.1    Maeda, S.2    Sternberg, E.3
  • 38
    • 77956131970 scopus 로고    scopus 로고
    • Altered expression and distribution of cathepsins in neuronopathic forms of Gaucher disease and in other sphingolipidoses
    • Vitner EB, Dekel H, Zigdon H, Shachar T, Farfel-Becker T, Eilam R, et al. Altered expression and distribution of cathepsins in neuronopathic forms of Gaucher disease and in other sphingolipidoses. Hum Mol Genet 2010a; 19: 3583-90.
    • (2010) Hum Mol Genet , vol.19 , pp. 3583-3590
    • Vitner, E.B.1    Dekel, H.2    Zigdon, H.3    Shachar, T.4    Farfel-Becker, T.5    Eilam, R.6
  • 39
    • 77954225471 scopus 로고    scopus 로고
    • Common and uncommon pathogenic cascades in lysosomal storage diseases
    • Vitner EB, Platt FM, Futerman AH. Common and uncommon pathogenic cascades in lysosomal storage diseases. J Biol Chem 2010b; 285: 20423-7.
    • (2010) J Biol Chem , vol.285 , pp. 20423-20427
    • Vitner, E.B.1    Platt, F.M.2    Futerman, A.H.3
  • 40
    • 0034718598 scopus 로고    scopus 로고
    • Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation
    • Wada R, Tifft CJ, Proia RL. Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation. Proc Natl Acad Sci USA 2000; 97: 10954-9.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10954-10959
    • Wada, R.1    Tifft, C.J.2    Proia, R.L.3
  • 43
    • 2942563944 scopus 로고    scopus 로고
    • Deletion of macrophage-inflammatory protein 1 alpha retards neurodegeneration in Sandhoff disease mice
    • Wu YP, Proia RL. Deletion of macrophage-inflammatory protein 1 alpha retards neurodegeneration in Sandhoff disease mice. Proc Natl Acad Sci USA 2004; 101: 8425-30.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8425-8430
    • Wu, Y.P.1    Proia, R.L.2
  • 44
    • 77958197729 scopus 로고    scopus 로고
    • Roles of heparan sulfate in mammalian brain development current views based on the findings from Ext1 conditional knockout studies
    • Yamaguchi Y, Inatani M, Matsumoto Y, Ogawa J, Irie F. Roles of heparan sulfate in mammalian brain development current views based on the findings from Ext1 conditional knockout studies. Prog Mol Biol Transl Sci 2010; 93: 133-52.
    • (2010) Prog Mol Biol Transl Sci , vol.93 , pp. 133-152
    • Yamaguchi, Y.1    Inatani, M.2    Matsumoto, Y.3    Ogawa, J.4    Irie, F.5
  • 45
    • 79959925894 scopus 로고    scopus 로고
    • Alpha-synuclein interacts with glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseases
    • Yap TL, Gruschus JM, Velayati A, Westbroek W, Goldin E, Moaven N, et al. Alpha-synuclein interacts with glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseases. J Biol Chem 2011; 286: 28080-8.
    • (2011) J Biol Chem , vol.286 , pp. 28080-28088
    • Yap, T.L.1    Gruschus, J.M.2    Velayati, A.3    Westbroek, W.4    Goldin, E.5    Moaven, N.6


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