Vision from next generation sequencing: Multi-dimensional genome-wide analysis for producing gene regulatory networks underlying retinal development, aging and disease

Progress in Retinal and Eye Research

Volumn 46, Issue , 2015, Pages 1-30

  Yang, Hyun Jin ^a   Ratnapriya, Rinki ^a   Cogliati, Tiziana ^a   Kim, Jung Woong ^a   Swaroop, Anand ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

ChIP seq; EQTL; Gene regulatory network; High throughput genomics; Inherited blindness; Macular degeneration; Network medicine; Pathway based drug discovery; Personalized medicine; Photoreceptor; Retinal degeneration; RNA seq; Systems biology; Whole exome sequencing

Indexed keywords

MICRORNA; PROTEOME; TRANSCRIPTION FACTOR; TRANSCRIPTOME;

AGING; CELL DIFFERENTIATION; DNA SEQUENCE; EPIGENETICS; GENE EXPRESSION PROFILING; GENE MUTATION; GENE REGULATORY NETWORK; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE ENVIRONMENT INTERACTION; HERITABILITY; HOMEOSTASIS; HUMAN; NEXT GENERATION SEQUENCING; PATHOGENESIS; PATTERN RECOGNITION; PHOTORECEPTOR; PRIORITY JOURNAL; RETINA DEVELOPMENT; RETINA DISEASE; REVIEW; TRANSCRIPTION REGULATION; VISION; BIOLOGY; EMBRYOLOGY; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HIGH THROUGHPUT SEQUENCING; PROCEDURES; RETINA;

AGING; COMPUTATIONAL BIOLOGY; GENE REGULATORY NETWORKS; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; RETINA; RETINAL DISEASES; SEQUENCE ANALYSIS, DNA;

EID: 84928050463     PISSN: 13509462     EISSN: 18731635     Source Type: Journal    
DOI: 10.1016/j.preteyeres.2015.01.005     Document Type: Review

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