Pharmacogenetics for genes associated with age-related macular degeneration in the comparison of AMD treatments trials (CATT)

Ophthalmology

Volumn 120, Issue 3, 2013, Pages 593-599

  Hagstrom, Stephanie A ^a,b   Ying, Gui Shuang ^c   Pauer, Gayle J T ^a   Sturgill Short, Gwen M ^a   Huang, Jiayan ^c   Callanan, David G ^d   Kim, Ivana K ^e   Klein, Michael L ^f   Maguire, Maureen G ^c   Martin, Daniel F ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d TEXAS RETINA ASSOCIATES   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; RANIBIZUMAB;

AGED; ALLELE; ARTICLE; CLINICAL TRIAL; FEMALE; FLUORESCENCE ANGIOGRAPHY; GENE EXPRESSION; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PHARMACOGENETICS; PRIORITY JOURNAL; RETINA FOVEA; RETINA MACULA AGE RELATED DEGENERATION; RETINAL THICKNESS; SINGLE NUCLEOTIDE POLYMORPHISM; SUBRETINAL NEOVASCULARIZATION; TREATMENT DURATION; TREATMENT RESPONSE; VISUAL ACUITY;

AGED; AGED, 80 AND OVER; ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL, HUMANIZED; COMPLEMENT C3; COMPLEMENT FACTOR H; FEMALE; FLUORESCEIN ANGIOGRAPHY; GENE FREQUENCY; GENOTYPE; HUMANS; MACULAR DEGENERATION; MALE; PHARMACOGENETICS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; PROTEINS; SERINE ENDOPEPTIDASES; TOMOGRAPHY, OPTICAL COHERENCE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VISUAL ACUITY;

EID: 84875209738     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2012.11.037     Document Type: Article

References (23)

1. CATT Research Group Ranibizumab and bevacizumab for neovascular age-related macular degeneration N Engl J Med 364 2011 1897 1908
2. X. Ding, M. Patel, C.C. Chan Molecular pathology of age-related macular degeneration Prog Retin Eye Res 28 2009 1 18
3. M.M. Deangelis, A.C. Silveira, E.A. Carr, I.K. Kim Genetics of age-related macular degeneration: current concepts, future directions Semin Ophthalmol 26 2011 77 93
4. M.A. Brantley Jr, A.M. Fang, J.M. King Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab Ophthalmology 114 2007 2168 2173 (Pubitemid 350181136)
5. A.Y. Lee, A.K. Raya, S.M. Kymes Pharmacogenetics of complement factor H (Y402H) and treatment of exudative age-related macular degeneration with ranibizumab Br J Ophthalmol 93 2009 610 613
6. S.J. Teper, A. Nowinska, J. Pilat et al. Involvement of genetic factors in the response to a variable-dosing ranibizumab treatment regimen for age-related macular degeneration Mol Vis [serial online] 16 2010 2598 2604 http://www.molvis.org/molvis/v16/a278/ Accessed October 27, 2012
7. C. Nischler, H. Oberkofler, C. Ortner Complement factor H Y402H gene polymorphism and response to intravitreal bevacizumab in exudative age-related macular degeneration [report online] Acta Ophthalmol 89 2011 e344 e349
8. P.J. Francis The influence of genetics on response to treatment with ranibizumab (Lucentis) for age-related macular degeneration: the Lucentis Genotype Study (an American Ophthalmological Society thesis) Trans Am Ophthalmol Soc 109 2011 115 156
9. A. Orlin, D. Hadley, W. Chang Association between high-risk disease loci and response to anti-vascular endothelial growth factor treatment for wet age-related macular degeneration Retina 32 2012 4 9
10. M. McKibbin, M. Ali, S. Bansal CFH, VEGF and HTRA1 promoter genotype may influence the response to intravitreal ranibizumab therapy for neovascular age-related macular degeneration Br J Ophthalmol 96 2012 208 212
11. B. Kloeckener-Gruissem, D. Barthelmes, S. Labs Genetic association with response to intravitreal ranibizumab in patients with neovascular AMD Invest Ophthalmol Vis Sci 52 2011 4694 4702
12. S.G. Schwartz, M.A. Brantley Jr Pharmacogenetics and age-related macular degeneration J Ophthalmol [serial online] 2011 2011 252549 http://www.ncbi.nlm. nih.gov/pmc/articles/PMC3199209/ Accessed October 27, 2012
13. R.W. Beck, P.S. Moke, A.H. Turpin A computerized method of visual acuity testing: adaptation of the Early Treatment of Diabetic Retinopathy Study testing protocol Am J Ophthalmol 135 2003 194 205 (Pubitemid 36151797)
14. A. Chan, J.S. Duker, T.H. Ko Normal macular thickness measurements in healthy eyes using Stratus optical coherence tomography Arch Ophthalmol 124 2006 193 198 (Pubitemid 43247068)
15. J.E. Grunwald, D. Ebenezer, G.S. Ying CATT Research Group Photographic assessment of baseline fundus morphologic features in the comparison of age-related macular degeneration treatments trials Ophthalmology 119 2012 1634 1641
16. D.G. Roberts, T.B. Morrison, S.N. Liu-Cordero A nanoliter fluidic platform for large-scale single nucleotide polymorphism genotyping Biotechniques 46 suppl 2009 ix xiii
17. S.C. Zeger, K.Y. Liang Models for longitudinal data: a generalized estimating equation approach Biometrics 44 1986 1049 1060
18. J. Gu, G.J. Pauer, X. Yue Clinical Genomic and Proteomic AMD Study Group Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers Mol Cell Proteomics 8 2009 1338 1349
19. S.B. Bressler Introduction: understanding the role of angiogenesis and antiangiogenic agents in age-related macular degeneration Ophthalmology 116 suppl 2009 S1 S7
20. Y. Tong, J. Liao, Y. Zhang LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: a HuGE review and meta-analysis Mol Vis [serial online] 16 2010 1958 1981 http://www.molvis.org/ molvis/v16/a213/ Accessed October 27, 2012
21. L. Sobrin, R. Reynolds, Y. Yu ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration Am J Ophthalmol 151 2011 345 352
22. A. Kanda, W. Chen, M. Othman A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration Proc Natl Acad Sci U S A 104 2007 16227 16232 (Pubitemid 350099389)
23. A. Dewan, M. Liu, S. Hartman HTRA1 promoter polymorphism in wet age-related macular degeneration Science 314 2006 989 992 (Pubitemid 44749943)