-
1
-
-
77954541844
-
Single-cell NF-kB dynamics reveal digital activation and analogue information processing
-
Tay, S. et al. Single-cell NF-kB dynamics reveal digital activation and analogue information processing. Nature 466, 267-271 (2010).
-
(2010)
Nature
, vol.466
, pp. 267-271
-
-
Tay, S.1
-
2
-
-
67650319009
-
Single-molecule approaches to stochastic gene expression
-
Raj, A. & Van Oudenaarden, A. Single-molecule approaches to stochastic gene expression. Ann. Rev. Biophys. 38, 255-270 (2009).
-
(2009)
Ann. Rev. Biophys.
, vol.38
, pp. 255-270
-
-
Raj, A.1
Van Oudenaarden, A.2
-
3
-
-
58049200628
-
Characterizing heterogeneous cellular responses to perturbations
-
Slack, M. D., Martinez, E. D., Wu, L. F. & Altschuler, S. J. Characterizing heterogeneous cellular responses to perturbations. Proc. Natl Acad. Sci. USA 105, 19306-19311 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 19306-19311
-
-
Slack, M.D.1
Martinez, E.D.2
Wu, L.F.3
Altschuler, S.J.4
-
4
-
-
77950809059
-
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
-
Sharma, S. V. et al. A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. Cell 141, 69-80 (2010).
-
(2010)
Cell
, vol.141
, pp. 69-80
-
-
Sharma, S.V.1
-
5
-
-
66249136447
-
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
-
Spencer, S. L., Gaudet, S., Albeck, J. G., Burke, J. M. & Sorger, P. K. Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature 459, 428-432 (2009).
-
(2009)
Nature
, vol.459
, pp. 428-432
-
-
Spencer, S.L.1
Gaudet, S.2
Albeck, J.G.3
Burke, J.M.4
Sorger, P.K.5
-
7
-
-
81955161928
-
We are all individuals: Causes and consequences of non-genetic heterogeneity in mammalian cells
-
Loewer, A. & Lahav, G. We are all individuals: causes and consequences of non-genetic heterogeneity in mammalian cells. Curr. Opin. Genet. Dev. 21, 753-758 (2011).
-
(2011)
Curr. Opin. Genet. Dev.
, vol.21
, pp. 753-758
-
-
Loewer, A.1
Lahav, G.2
-
8
-
-
78649875958
-
Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response
-
Feinerman, O. et al. Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response. Mol. Syst. Biol. 6, 437-453 (2010).
-
(2010)
Mol. Syst. Biol.
, vol.6
, pp. 437-453
-
-
Feinerman, O.1
-
9
-
-
53849146767
-
Bistability, epigenetics, and bet-hedging in bacteria
-
Veening, J.-W., Smits, W. K. & Kuipers, O. P. Bistability, epigenetics, and bet-hedging in bacteria. Ann. Rev. Microbiol. 62, 193-210 (2008).
-
(2008)
Ann. Rev. Microbiol.
, vol.62
, pp. 193-210
-
-
Veening, J.-W.1
Smits, W.K.2
Kuipers, O.P.3
-
10
-
-
84880953116
-
Stochastic cytokine expression induces mixed T helper cell states
-
Fang, M., Xie, H., Dougan, S. K., Ploegh, H. & Van Oudenaarden, A. Stochastic cytokine expression induces mixed T helper cell states. PLoS Biol. 11, e1001618 (2013).
-
(2013)
PLoS Biol.
, vol.11
-
-
Fang, M.1
Xie, H.2
Dougan, S.K.3
Ploegh, H.4
Van Oudenaarden, A.5
-
11
-
-
84860257802
-
Interplay between gene expression noise and regulatory network architecture
-
Chalancon, G. et al. Interplay between gene expression noise and regulatory network architecture. Trends Genet. 28, 221-232 (2012).
-
(2012)
Trends Genet.
, vol.28
, pp. 221-232
-
-
Chalancon, G.1
-
12
-
-
79955750055
-
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum
-
Bendall, S. C. et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science 332, 687-696 (2011).
-
(2011)
Science
, vol.332
, pp. 687-696
-
-
Bendall, S.C.1
-
13
-
-
84866953427
-
CEL-Seq: Single-cell RNA-Seq by multiplexed linear amplification
-
Hashimshony, T., Wagner, F., Sher, N. & Yanai, I. CEL-Seq: single-cell RNA-Seq by multiplexed linear amplification. Cell Rep. 2, 666-673 (2012).
-
(2012)
Cell Rep.
, vol.2
, pp. 666-673
-
-
Hashimshony, T.1
Wagner, F.2
Sher, N.3
Yanai, I.4
-
14
-
-
79959403670
-
Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq
-
Islam, S. et al. Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq. Genome Res. 21, 1160-1167 (2011).
-
(2011)
Genome Res.
, vol.21
, pp. 1160-1167
-
-
Islam, S.1
-
15
-
-
84864880991
-
Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
-
Ramsköld, D. et al. Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells. Nature Biotechnol. 30, 777-782 (2012).
-
(2012)
Nature Biotechnol.
, vol.30
, pp. 777-782
-
-
Ramsköld, D.1
-
16
-
-
84878997106
-
Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells
-
Shalek, A. K. et al. Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells. Nature 498, 236-240 (2013).
-
(2013)
Nature
, vol.498
, pp. 236-240
-
-
Shalek, A.K.1
-
17
-
-
67349146589
-
MRNA-Seq whole-transcriptome analysis of a single cell
-
Tang, F. et al. mRNA-Seq whole-transcriptome analysis of a single cell. Nature Methods 6, 377-382 (2009).
-
(2009)
Nature Methods
, vol.6
, pp. 377-382
-
-
Tang, F.1
-
18
-
-
70349882120
-
Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses
-
Amit, I. et al. Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. Science 326, 257-263 (2009).
-
(2009)
Science
, vol.326
, pp. 257-263
-
-
Amit, I.1
-
19
-
-
84893910301
-
Quantitative assessment of single-cell RNA-sequencing methods
-
Wu, A. R. et al. Quantitative assessment of single-cell RNA-sequencing methods. Nature Methods 11, 41-46 (2014).
-
(2014)
Nature Methods
, vol.11
, pp. 41-46
-
-
Wu, A.R.1
-
20
-
-
0042424602
-
Statistical significance for genomewide studies
-
Storey, J. D. & Tibshirani, R. Statistical significance for genomewide studies. Proc. Natl Acad. Sci. USA 100, 9440-9445 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 9440-9445
-
-
Storey, J.D.1
Tibshirani, R.2
-
21
-
-
84874321000
-
Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments
-
McDavid, A. et al. Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments. Bioinformatics 29, 461-467 (2013).
-
(2013)
Bioinformatics
, vol.29
, pp. 461-467
-
-
McDavid, A.1
-
22
-
-
84859621573
-
Highly multiplexed and strand-specific single-cell RNA 59 end sequencing
-
Islam, S. et al. Highly multiplexed and strand-specific single-cell RNA 59 end sequencing. Nature Protocols 7, 823-828 (2012).
-
(2012)
Nature Protocols
, vol.7
, pp. 823-828
-
-
Islam, S.1
-
23
-
-
84895562012
-
From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing
-
Marinov, G. K. et al. From single-cell to cell-pool transcriptomes: stochasticity in gene expression and RNA splicing. Genome Res. 24, 496-510 (2014).
-
(2014)
Genome Res.
, vol.24
, pp. 496-510
-
-
Marinov, G.K.1
-
24
-
-
84866303839
-
A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation inmammals
-
Garber, M. et al. A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation inmammals. Mol. Cell 47, 810-822 (2012).
-
(2012)
Mol. Cell
, vol.47
, pp. 810-822
-
-
Garber, M.1
-
25
-
-
84862004740
-
Visualising individual sequence-specific protein-DNA interactions in situ
-
Weibrecht, I. et al. Visualising individual sequence-specific protein-DNA interactions in situ. New Biotechnol. 29, 589-598 (2012).
-
(2012)
New Biotechnol.
, vol.29
, pp. 589-598
-
-
Weibrecht, I.1
-
26
-
-
77951187551
-
A noisy paracrine signal determines the cellular NFkB response to lipopolysaccharide
-
Lee, T. K. et al. A noisy paracrine signal determines the cellular NFkB response to lipopolysaccharide. Sci. Signal. 2, ra65 (2009).
-
(2009)
Sci. Signal.
, vol.2
-
-
Lee, T.K.1
-
27
-
-
84883491202
-
Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response
-
Rand, U. et al. Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response. Mol. Syst. Biol. 8, 584 (2012).
-
(2012)
Mol. Syst. Biol.
, vol.8
, pp. 584
-
-
Rand, U.1
-
28
-
-
84856480470
-
Stochastic expression of the interferon-b gene
-
Zhao, M., Zhang, J., Phatnani, H., Scheu, S. & Maniatis, T. Stochastic expression of the interferon-b gene. PLoS Biol. 10, e1001249 (2012).
-
(2012)
PLoS Biol.
, vol.10
-
-
Zhao, M.1
Zhang, J.2
Phatnani, H.3
Scheu, S.4
Maniatis, T.5
-
29
-
-
70349466529
-
Population context determines cell-to-cell variability in endocytosis and virus infection
-
Snijder, B. et al. Population context determines cell-to-cell variability in endocytosis and virus infection. Nature 461, 520-523 (2009).
-
(2009)
Nature
, vol.461
, pp. 520-523
-
-
Snijder, B.1
-
30
-
-
38449100329
-
Interferons as anti-inflammatory mediators
-
Benveniste, E. N., Qin, H.& Type, I. Interferons as anti-inflammatory mediators. Sci. STKE 416, pe70 (2007).
-
(2007)
Sci. STKE
, vol.416
-
-
Benveniste, E.N.1
Qin, H.2
Type, I.3
-
31
-
-
0035006210
-
Keratins and the keratinocyte activation cycle
-
Freedberg, I. M., Tomic-Canic, M., Komine, M. & Blumenberg, M. Keratins and the keratinocyte activation cycle. J. Invest. Dermatol. 116, 633-640 (2001).
-
(2001)
J. Invest. Dermatol.
, vol.116
, pp. 633-640
-
-
Freedberg, I.M.1
Tomic-Canic, M.2
Komine, M.3
Blumenberg, M.4
-
32
-
-
79955768436
-
Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells
-
Rabani, M. et al. Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells. Nature Biotechnol. 29, 436-442 (2011).
-
(2011)
Nature Biotechnol.
, vol.29
, pp. 436-442
-
-
Rabani, M.1
-
33
-
-
27944442272
-
Quorum sensing: Cell-to-cell communication in bacteria
-
Waters, C. M. & Bassler, B. L. Quorum sensing: cell-to-cell communication in bacteria. Ann. Rev. Cell Dev. Biol. 21, 319-346 (2005).
-
(2005)
Ann. Rev. Cell Dev. Biol.
, vol.21
, pp. 319-346
-
-
Waters, C.M.1
Bassler, B.L.2
-
34
-
-
33748447541
-
Interferon in systemic lupus erythematosus and other autoimmune diseases
-
Banchereau, J., Pascual, V. & Type, I. Interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity 25, 383-392 (2006).
-
(2006)
Immunity
, vol.25
, pp. 383-392
-
-
Banchereau, J.1
Pascual, V.2
Type, I.3
-
35
-
-
75149189005
-
Type i interferons: Crucial participants in disease amplification in autoimmunity
-
Hall, J. C. & Rosen, A. Type I interferons: crucial participants in disease amplification in autoimmunity. Nature Rev. Rheumatol. 6, 40-49 (2010).
-
(2010)
Nature Rev. Rheumatol.
, vol.6
, pp. 40-49
-
-
Hall, J.C.1
Rosen, A.2
-
36
-
-
79961123152
-
RSEM: Accurate transcript quantification from RNA-Seq data with or without a reference genome
-
Li, B. & Dewey, C. N. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics 12, 323 (2011).
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 323
-
-
Li, B.1
Dewey, C.N.2
|