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Volumn 15, Issue 2, 2014, Pages 69-81

Dynamic regulation of transcriptional states by chromatin and transcription factors

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE; NUCLEOPROTEIN; REGULATOR PROTEIN; TRANSCRIPTION FACTOR;

EID: 84892800329     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg3623     Document Type: Review
Times cited : (378)

References (124)
  • 1
    • 84874116331 scopus 로고    scopus 로고
    • Chromatin: Receiver and quarterback for cellular signals
    • Johnson, D. G. & Dent, S. Y. Chromatin: receiver and quarterback for cellular signals. Cell 152, 685-689 (2013).
    • (2013) Cell , vol.152 , pp. 685-689
    • Johnson, D.G.1    Dent, S.Y.2
  • 2
    • 84863890567 scopus 로고    scopus 로고
    • Genomic approaches towards finding cis-regulatory modules in animals
    • Hardison, R. C. & Taylor, J. Genomic approaches towards finding cis-regulatory modules in animals. Nature Rev. Genet. 13, 469-483 (2012).
    • (2012) Nature Rev. Genet. , vol.13 , pp. 469-483
    • Hardison, R.C.1    Taylor, J.2
  • 3
    • 80053144962 scopus 로고    scopus 로고
    • A decade of exploring the cancer epigenome-biological and translational implications
    • Baylin, S. B. & Jones, P. A. A decade of exploring the cancer epigenome-biological and translational implications. Nature Rev. Cancer 11, 726-734 (2011).
    • (2011) Nature Rev. Cancer , vol.11 , pp. 726-734
    • Baylin, S.B.1    Jones, P.A.2
  • 4
    • 84865249952 scopus 로고    scopus 로고
    • Transcription factors: From enhancer binding to developmental control
    • Spitz, F. & Furlong, E. E. Transcription factors: from enhancer binding to developmental control. Nature Rev. Genet. 13, 613-626 (2012).
    • (2012) Nature Rev. Genet. , vol.13 , pp. 613-626
    • Spitz, F.1    Furlong, E.E.2
  • 5
    • 80053516108 scopus 로고    scopus 로고
    • Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration
    • Wu, W. et al. Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration. Genome Res. 21, 1659-1671 (2011).
    • (2011) Genome Res. , vol.21 , pp. 1659-1671
    • Wu, W.1
  • 6
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik, W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447, 425-432 (2007).
    • (2007) Nature , vol.447 , pp. 425-432
    • Reik, W.1
  • 7
    • 33947301272 scopus 로고    scopus 로고
    • Epigenetic signatures of stem-cell identity
    • Spivakov, M. & Fisher, A. G. Epigenetic signatures of stem-cell identity. Nature Rev. Genet. 8, 263-271 (2007).
    • (2007) Nature Rev. Genet. , vol.8 , pp. 263-271
    • Spivakov, M.1    Fisher, A.G.2
  • 8
    • 84884829249 scopus 로고    scopus 로고
    • Mapping human epigenomes
    • Rivera, C. M. & Ren, B. Mapping human epigenomes. Cell 155, 39-55 (2013).
    • (2013) Cell , vol.155 , pp. 39-55
    • Rivera, C.M.1    Ren, B.2
  • 9
    • 84865755978 scopus 로고    scopus 로고
    • The accessible chromatin landscape of the human genome
    • Thurman, R. E. et al. The accessible chromatin landscape of the human genome. Nature 489, 75-82 (2012).
    • (2012) Nature , vol.489 , pp. 75-82
    • Thurman, R.E.1
  • 10
    • 84857111200 scopus 로고    scopus 로고
    • DNase i sensitivity QTLs are a major determinant of human expression variation
    • Degner, J. F. et al. DNase I sensitivity QTLs are a major determinant of human expression variation. Nature 482, 390-394 (2012).
    • (2012) Nature , vol.482 , pp. 390-394
    • Degner, J.F.1
  • 11
    • 84865800494 scopus 로고    scopus 로고
    • The long-range interaction landscape of gene promoters
    • Sanyal, A., Lajoie, B. R., Jain, G. & Dekker, J. The long-range interaction landscape of gene promoters. Nature 489, 109-113 (2012).
    • (2012) Nature , vol.489 , pp. 109-113
    • Sanyal, A.1    Lajoie, B.R.2    Jain, G.3    Dekker, J.4
  • 12
    • 82455199121 scopus 로고    scopus 로고
    • What do expression dynamics tell us about the mechanism of transcription?
    • Larson, D. R. What do expression dynamics tell us about the mechanism of transcription? Curr. Opin. Genet. Dev. 21, 591-599 (2011).
    • (2011) Curr. Opin. Genet. Dev. , vol.21 , pp. 591-599
    • Larson, D.R.1
  • 13
    • 33646926758 scopus 로고    scopus 로고
    • Dynamic nucleosomes and gene transcription
    • Mellor, J. Dynamic nucleosomes and gene transcription. Trends Genet. 22, 320-329 (2006).
    • (2006) Trends Genet. , vol.22 , pp. 320-329
    • Mellor, J.1
  • 14
    • 0343415609 scopus 로고    scopus 로고
    • The glucocorticoid receptor: Rapid exchange with regulatory sites in living cells
    • McNally, J. G., Mueller, W. G., Walker, D., Wolford, R. G. & Hager, G. L. The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. Science 287, 1262-1265 (2000).
    • (2000) Science , vol.287 , pp. 1262-1265
    • McNally, J.G.1    Mueller, W.G.2    Walker, D.3    Wolford, R.G.4    Hager, G.L.5
  • 15
    • 19544379881 scopus 로고    scopus 로고
    • Stochasticity in gene expression: From theories to phenotypes
    • Kaern, M., Elston, T. C., Blake, W. J. & Collins, J. J. Stochasticity in gene expression: from theories to phenotypes. Nature Rev. Genet. 6, 451-464 (2005).
    • (2005) Nature Rev. Genet. , vol.6 , pp. 451-464
    • Kaern, M.1    Elston, T.C.2    Blake, W.J.3    Collins, J.J.4
  • 16
    • 84880920116 scopus 로고    scopus 로고
    • Eukaryotic transcriptional dynamics: From single molecules to cell populations
    • Coulon, A., Chow, C. C., Singer, R. H. & Larson, D. R. Eukaryotic transcriptional dynamics: from single molecules to cell populations. Nature Rev. Genet. 14, 572-584 (2013).
    • (2013) Nature Rev. Genet. , vol.14 , pp. 572-584
    • Coulon, A.1    Chow, C.C.2    Singer, R.H.3    Larson, D.R.4
  • 17
    • 38649099445 scopus 로고    scopus 로고
    • High-resolution mapping and characterization of open chromatin across the genome
    • Boyle, A. P. et al. High-resolution mapping and characterization of open chromatin across the genome. Cell 132, 311-322 (2008).
    • (2008) Cell , vol.132 , pp. 311-322
    • Boyle, A.P.1
  • 18
    • 79952184341 scopus 로고    scopus 로고
    • Chromatin accessibility pre-determines glucocorticoid receptor binding patterns
    • John, S. et al. Chromatin accessibility pre-determines glucocorticoid receptor binding patterns. Nature Genet. 43, 264-268 (2011).
    • (2011) Nature Genet. , vol.43 , pp. 264-268
    • John, S.1
  • 19
    • 67651111994 scopus 로고    scopus 로고
    • Early chromatin unfolding by RUNX1: A molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program
    • Hoogenkamp, M. et al. Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program. Blood 114, 299-309 (2009).
    • (2009) Blood , vol.114 , pp. 299-309
    • Hoogenkamp, M.1
  • 20
    • 79954992662 scopus 로고    scopus 로고
    • Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis
    • Siersbaek, R. et al. Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis. EMBO J. 30, 1459-1472 (2011).
    • (2011) EMBO J. , vol.30 , pp. 1459-1472
    • Siersbaek, R.1
  • 21
    • 84865121188 scopus 로고    scopus 로고
    • An encyclopedia of mouse DNA elements (mouse ENCODE)
    • Stamatoyannopoulos, J. A. et al. An encyclopedia of mouse DNA elements (mouse ENCODE). Genome Biol. 13, 418 (2012).
    • (2012) Genome Biol. , vol.13 , pp. 418
    • Stamatoyannopoulos, J.A.1
  • 22
    • 79959911826 scopus 로고    scopus 로고
    • Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding
    • Biddie, S. C. et al. Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding. Mol. Cell 43, 145-155 (2011).
    • (2011) Mol. Cell , vol.43 , pp. 145-155
    • Biddie, S.C.1
  • 23
    • 71749120382 scopus 로고    scopus 로고
    • Finding distal regulatory elements in the human genome
    • Heintzman, N. D. & Ren, B. Finding distal regulatory elements in the human genome. Curr. Opin. Genet. Dev. 19, 541-549 (2009).
    • (2009) Curr. Opin. Genet. Dev. , vol.19 , pp. 541-549
    • Heintzman, N.D.1    Ren, B.2
  • 24
    • 33644530060 scopus 로고    scopus 로고
    • A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-κB-dependent gene activity
    • Bosisio, D. et al. A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-κB-dependent gene activity. EMBO J. 25, 798-810 (2006).
    • (2006) EMBO J. , vol.25 , pp. 798-810
    • Bosisio, D.1
  • 25
    • 33750451557 scopus 로고    scopus 로고
    • Estrogen-receptor-α exchange and chromatin dynamics are ligand-and domain-dependent
    • Sharp, Z. D. et al. Estrogen-receptor-α exchange and chromatin dynamics are ligand-and domain-dependent. J. Cell Sci. 119, 4101-4116 (2006).
    • (2006) J. Cell Sci. , vol.119 , pp. 4101-4116
    • Sharp, Z.D.1
  • 26
    • 33748304273 scopus 로고    scopus 로고
    • Dynamics of heat shock factor association with native gene loci in living cells
    • Yao, J., Munson, K. M., Webb, W. W. & Lis, J. T. Dynamics of heat shock factor association with native gene loci in living cells. Nature 442, 1050-1053 (2006).
    • (2006) Nature , vol.442 , pp. 1050-1053
    • Yao, J.1    Munson, K.M.2    Webb, W.W.3    Lis, J.T.4
  • 27
    • 84859582058 scopus 로고    scopus 로고
    • Genome-wide protein-DNA binding dynamics suggest a molecular clutch for transcription factor function
    • Lickwar, C. R., Mueller, F., Hanlon, S. E., McNally, J. G. & Lieb, J. D. Genome-wide protein-DNA binding dynamics suggest a molecular clutch for transcription factor function. Nature 484, 251-255 (2012).
    • (2012) Nature , vol.484 , pp. 251-255
    • Lickwar, C.R.1    Mueller, F.2    Hanlon, S.E.3    McNally, J.G.4    Lieb, J.D.5
  • 28
    • 78651298061 scopus 로고    scopus 로고
    • Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload
    • Kuipers, M. A. et al. Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload. J. Cell Biol. 192, 29-41 (2011).
    • (2011) J. Cell Biol. , vol.192 , pp. 29-41
    • Kuipers, M.A.1
  • 29
    • 82355190137 scopus 로고    scopus 로고
    • Assembly of the transcription machinery: Ordered and stable random and dynamic, or both?
    • Stasevich, T. J. & McNally, J. G. Assembly of the transcription machinery: ordered and stable, random and dynamic, or both? Chromosoma 120, 533-545 (2011).
    • (2011) Chromosoma , vol.120 , pp. 533-545
    • Stasevich, T.J.1    McNally, J.G.2
  • 30
    • 77954815037 scopus 로고    scopus 로고
    • FRAP and kinetic modeling in the analysis of nuclear protein dynamics: What do we really know?
    • Mueller, F., Mazza, D., Stasevich, T. J. & McNally, J. G. FRAP and kinetic modeling in the analysis of nuclear protein dynamics: what do we really know? Curr. Opin. Cell Biol. 22, 403-411 (2010).
    • (2010) Curr. Opin. Cell Biol. , vol.22 , pp. 403-411
    • Mueller, F.1    Mazza, D.2    Stasevich, T.J.3    McNally, J.G.4
  • 31
    • 84865708757 scopus 로고    scopus 로고
    • An expansive human regulatory lexicon encoded in transcription factor footprints
    • Neph, S. et al. An expansive human regulatory lexicon encoded in transcription factor footprints. Nature 489, 83-90 (2012).
    • (2012) Nature , vol.489 , pp. 83-90
    • Neph, S.1
  • 32
    • 84861964135 scopus 로고    scopus 로고
    • Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor
    • Deng, W. et al. Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell 149, 1233-1244 (2012).
    • (2012) Cell , vol.149 , pp. 1233-1244
    • Deng, W.1
  • 33
    • 77955629953 scopus 로고    scopus 로고
    • Genome-wide analysis of estrogen receptor α DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation
    • Stender, J. D. et al. Genome-wide analysis of estrogen receptor α DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation. Mol. Cell. Biol. 30, 3943-3955 (2010).
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 3943-3955
    • Stender, J.D.1
  • 34
    • 80052656113 scopus 로고
    • Targeting chromatin remodelers: Signals and search mechanisms
    • Erdel, F., Krug, J., Langst, G. & Rippe, K. Targeting chromatin remodelers: signals and search mechanisms. Biochim. Biophys. Acta 1809, 497-508 (2011).
    • (1809) Biochim. Biophys. Acta , pp. 497-508
    • Erdel, F.1    Krug, J.2    Langst, G.3    Rippe, K.4
  • 35
    • 35848958821 scopus 로고    scopus 로고
    • Chromatin remodeling: Insights and intrigue from single-molecule studies
    • Cairns, B. R. Chromatin remodeling: insights and intrigue from single-molecule studies. Nature Struct. Mol. Biol. 14, 989-996 (2007).
    • (2007) Nature Struct. Mol. Biol. , vol.14 , pp. 989-996
    • Cairns, B.R.1
  • 36
    • 67650725820 scopus 로고    scopus 로고
    • The biology of chromatin remodeling complexes
    • Clapier, C. R. & Cairns, B. R. The biology of chromatin remodeling complexes. Annu. Rev. Biochem. 78, 273-304 (2009).
    • (2009) Annu. Rev. Biochem. , vol.78 , pp. 273-304
    • Clapier, C.R.1    Cairns, B.R.2
  • 38
    • 79952539053 scopus 로고    scopus 로고
    • ATP-dependent chromatin remodeling: Genetics, genomics and mechanisms
    • Hargreaves, D. C. & Crabtree, G. R. ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Cell Res. 21, 396-420 (2011).
    • (2011) Cell Res. , vol.21 , pp. 396-420
    • Hargreaves, D.C.1    Crabtree, G.R.2
  • 39
    • 79952113300 scopus 로고    scopus 로고
    • Nucleosome dynamics and epigenetic stability
    • Korber, P. & Becker, P. B. Nucleosome dynamics and epigenetic stability. Essays Biochem. 48, 63-74 (2010).
    • (2010) Essays Biochem. , vol.48 , pp. 63-74
    • Korber, P.1    Becker, P.B.2
  • 40
    • 0037369952 scopus 로고    scopus 로고
    • Collaborative competition mechanism for gene activation in vivo
    • Miller, J. A. & Widom, J. Collaborative competition mechanism for gene activation in vivo. Mol. Cell. Biol. 23, 1623-1632 (2003).
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 1623-1632
    • Miller, J.A.1    Widom, J.2
  • 41
    • 78651107675 scopus 로고    scopus 로고
    • Nucleosome-mediated cooperativity between transcription factors
    • Mirny, L. A. Nucleosome-mediated cooperativity between transcription factors. Proc. Natl Acad. Sci. USA 107, 22534-22539 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 22534-22539
    • Mirny, L.A.1
  • 42
    • 78049343481 scopus 로고    scopus 로고
    • A lattice model for transcription factor access to nucleosomal DNA
    • Teif, V. B., Ettig, R. & Rippe, K. A lattice model for transcription factor access to nucleosomal DNA. Biophys. J. 99, 2597-2607 (2010).
    • (2010) Biophys. J. , vol.99 , pp. 2597-2607
    • Teif, V.B.1    Ettig, R.2    Rippe, K.3
  • 43
    • 80455144479 scopus 로고    scopus 로고
    • Pioneer transcription factors: Establishing competence for gene expression
    • Zaret, K. S. & Carroll, J. S. Pioneer transcription factors: establishing competence for gene expression. Genes Dev. 25, 2227-2241 (2011).
    • (2011) Genes Dev. , vol.25 , pp. 2227-2241
    • Zaret, K.S.1    Carroll, J.S.2
  • 44
    • 37249054901 scopus 로고    scopus 로고
    • Chromatin opening and stable perturbation of core histone: DNA contacts by FoxO1
    • Hatta, M. & Cirillo, L. A. Chromatin opening and stable perturbation of core histone: DNA contacts by FoxO1. J. Biol. Chem. 282, 35583-35593 (2007).
    • (2007) J. Biol. Chem. , vol.282 , pp. 35583-35593
    • Hatta, M.1    Cirillo, L.A.2
  • 45
    • 80054084614 scopus 로고    scopus 로고
    • Pioneer factors: Directing transcriptional regulators within the chromatin environment
    • Magnani, L., Eeckhoute, J. & Lupien, M. Pioneer factors: directing transcriptional regulators within the chromatin environment. Trends Genet. 27, 465-474 (2011).
    • (2011) Trends Genet. , vol.27 , pp. 465-474
    • Magnani, L.1    Eeckhoute, J.2    Lupien, M.3
  • 46
    • 40849085514 scopus 로고    scopus 로고
    • FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription
    • Lupien, M. et al. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell 132, 958-970 (2008).
    • (2008) Cell , vol.132 , pp. 958-970
    • Lupien, M.1
  • 47
    • 84861526574 scopus 로고    scopus 로고
    • Pioneer factors in hormone-dependent cancers
    • Jozwik, K. M. & Carroll, J. S. Pioneer factors in hormone-dependent cancers. Nature Rev. Cancer 12, 381-385 (2012).
    • (2012) Nature Rev. Cancer , vol.12 , pp. 381-385
    • Jozwik, K.M.1    Carroll, J.S.2
  • 48
    • 33846589909 scopus 로고    scopus 로고
    • Specific interactions of the wing domains of FOXA1 transcription factor with DNA
    • Cirillo, L. A. & Zaret, K. S. Specific interactions of the wing domains of FOXA1 transcription factor with DNA. J. Mol. Biol. 366, 720-724 (2007).
    • (2007) J. Mol. Biol. , vol.366 , pp. 720-724
    • Cirillo, L.A.1    Zaret, K.S.2
  • 49
    • 2942574467 scopus 로고    scopus 로고
    • Removal of promoter nucleosomes by disassembly rather than sliding in vivo
    • Boeger, H., Griesenbeck, J., Strattan, J. S. & Kornberg, R. D. Removal of promoter nucleosomes by disassembly rather than sliding in vivo. Mol. Cell 14, 667-673 (2004).
    • (2004) Mol. Cell , vol.14 , pp. 667-673
    • Boeger, H.1    Griesenbeck, J.2    Strattan, J.S.3    Kornberg, R.D.4
  • 50
    • 43049157587 scopus 로고    scopus 로고
    • Nucleosome retention and the stochastic nature of promoter chromatin remodeling for transcription
    • Boeger, H., Griesenbeck, J. & Kornberg, R. D. Nucleosome retention and the stochastic nature of promoter chromatin remodeling for transcription. Cell 133, 716-726 (2008).
    • (2008) Cell , vol.133 , pp. 716-726
    • Boeger, H.1    Griesenbeck, J.2    Kornberg, R.D.3
  • 51
    • 1942502820 scopus 로고    scopus 로고
    • Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling
    • Nagaich, A. K., Walker, D. A., Wolford, R. G. & Hager, G. L. Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling. Mol. Cell 14, 163-174 (2004).
    • (2004) Mol. Cell , vol.14 , pp. 163-174
    • Nagaich, A.K.1    Walker, D.A.2    Wolford, R.G.3    Hager, G.L.4
  • 53
    • 0036837670 scopus 로고    scopus 로고
    • High-resolution mapping of changes in histone-DNA contacts of nucleosomes remodeled by ISW2
    • Kassabov, S. R., Henry, N. M., Zofall, M., Tsukiyama, T. & Bartholomew, B. High-resolution mapping of changes in histone-DNA contacts of nucleosomes remodeled by ISW2. Mol. Cell. Biol. 22, 7524-7534 (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 7524-7534
    • Kassabov, S.R.1    Henry, N.M.2    Zofall, M.3    Tsukiyama, T.4    Bartholomew, B.5
  • 54
    • 80052000538 scopus 로고    scopus 로고
    • Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism
    • Voss, T. C. et al. Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism. Cell 146, 544-554 (2011).
    • (2011) Cell , vol.146 , pp. 544-554
    • Voss, T.C.1
  • 55
    • 68849103482 scopus 로고    scopus 로고
    • Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions
    • MacArthur, S. et al. Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions. Genome Biol. 10, R80 (2009).
    • (2009) Genome Biol. , vol.10
    • Macarthur, S.1
  • 56
    • 33747072322 scopus 로고    scopus 로고
    • Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster
    • Moorman, C. et al. Hotspots of transcription factor colocalization in the genome of Drosophila melanogaster. Proc. Natl Acad. Sci. USA 103, 12027-12032 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 12027-12032
    • Moorman, C.1
  • 57
    • 70449132583 scopus 로고    scopus 로고
    • Combinatorial binding predicts spatio-temporal cis-regulatory activity
    • Zinzen, R. P., Girardot, C., Gagneur, J., Braun, M. & Furlong, E. E. Combinatorial binding predicts spatio-temporal cis-regulatory activity. Nature 462, 65-70 (2009).
    • (2009) Nature , vol.462 , pp. 65-70
    • Zinzen, R.P.1    Girardot, C.2    Gagneur, J.3    Braun, M.4    Furlong, E.E.5
  • 58
    • 68949213578 scopus 로고    scopus 로고
    • Insights from genomic profiling of transcription factors
    • Farnham, P. J. Insights from genomic profiling of transcription factors. Nature Rev. Genet. 10, 605-616 (2009).
    • (2009) Nature Rev. Genet. , vol.10 , pp. 605-616
    • Farnham, P.J.1
  • 59
    • 78650331647 scopus 로고    scopus 로고
    • Identification of functional elements and regulatory circuits by Drosophila modENCODE
    • modENCODE Consortium et al.
    • modENCODE Consortium et al. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science 330, 1787-1797 (2010).
    • (2010) Science , vol.330 , pp. 1787-1797
  • 61
    • 0025790171 scopus 로고
    • In vivo footprinting of rat TAT gene: Dynamic interplay between the glucocorticoid receptor and a liver-specific factor
    • Rigaud, G., Roux, J., Pictet, R. & Grange, T. In vivo footprinting of rat TAT gene: dynamic interplay between the glucocorticoid receptor and a liver-specific factor. Cell 67, 977-986 (1991).
    • (1991) Cell , vol.67 , pp. 977-986
    • Rigaud, G.1    Roux, J.2    Pictet, R.3    Grange, T.4
  • 62
    • 84893777171 scopus 로고    scopus 로고
    • Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions
    • Morris, S. A. et al. Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions. Nature Struct. Mol. Biol. http://dx.doi.org/10.1038/nsmb.2718 (2013).
    • (2013) Nature Struct. Mol. Biol
    • Morris, S.A.1
  • 63
    • 79961051673 scopus 로고    scopus 로고
    • Separating intrinsic from extrinsic fluctuations in dynamic biological systems
    • Hilfinger, A. & Paulsson, J. Separating intrinsic from extrinsic fluctuations in dynamic biological systems. Proc. Natl Acad. Sci. USA 108, 12167-12172 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 12167-12172
    • Hilfinger, A.1    Paulsson, J.2
  • 64
    • 0036790975 scopus 로고    scopus 로고
    • Intrinsic and extrinsic contributions to stochasticity in gene expression
    • Swain, P. S., Elowitz, M. B. & Siggia, E. D. Intrinsic and extrinsic contributions to stochasticity in gene expression. Proc. Natl Acad. Sci. USA 99, 12795-12800 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 12795-12800
    • Swain, P.S.1    Elowitz, M.B.2    Siggia, E.D.3
  • 65
    • 79955488304 scopus 로고    scopus 로고
    • Dynamic analysis of stochastic transcription cycles
    • Harper, C. V. et al. Dynamic analysis of stochastic transcription cycles. PLoS. Biol. 9, e1000607 (2011).
    • (2011) PLoS. Biol. , vol.9
    • Harper, C.V.1
  • 66
    • 63849165373 scopus 로고    scopus 로고
    • Kinetic complexity of the global response to glucocorticoid receptor action
    • John, S. et al. Kinetic complexity of the global response to glucocorticoid receptor action. Endocrinology 150, 1766-1774 (2009).
    • (2009) Endocrinology , vol.150 , pp. 1766-1774
    • John, S.1
  • 67
    • 33749047898 scopus 로고    scopus 로고
    • Single cell analysis of glucocorticoid receptor action reveals that stochastic post-chromatin association mechanisms regulate ligand-specific transcription
    • Voss, T. C., John, S. & Hager, G. L. Single cell analysis of glucocorticoid receptor action reveals that stochastic post-chromatin association mechanisms regulate ligand-specific transcription. Mol. Endocrinol. 20, 2641-2655 (2006).
    • (2006) Mol. Endocrinol. , vol.20 , pp. 2641-2655
    • Voss, T.C.1    John, S.2    Hager, G.L.3
  • 68
    • 0037119587 scopus 로고    scopus 로고
    • Stochastic gene expression in a single cell
    • Elowitz, M. B., Levine, A. J., Siggia, E. D. & Swain, P. S. Stochastic gene expression in a single cell. Science 297, 1183-1186 (2002).
    • (2002) Science , vol.297 , pp. 1183-1186
    • Elowitz, M.B.1    Levine, A.J.2    Siggia, E.D.3    Swain, P.S.4
  • 69
    • 2942718723 scopus 로고    scopus 로고
    • Control of stochasticity in eukaryotic gene expression
    • Raser, J. M. & O'Shea, E. K. Control of stochasticity in eukaryotic gene expression. Science 304, 1811-1814 (2004).
    • (2004) Science , vol.304 , pp. 1811-1814
    • Raser, J.M.1    O'Shea, E.K.2
  • 70
    • 34249079154 scopus 로고    scopus 로고
    • Network motifs: Theory and experimental approaches
    • Alon, U. Network motifs: theory and experimental approaches. Nature Rev. Genet. 8, 450-461 (2007).
    • (2007) Nature Rev. Genet. , vol.8 , pp. 450-461
    • Alon, U.1
  • 71
    • 79952672993 scopus 로고    scopus 로고
    • Impulse control: Temporal dynamics in gene transcription
    • Yosef, N. & Regev, A. Impulse control: temporal dynamics in gene transcription. Cell 144, 886-896 (2011).
    • (2011) Cell , vol.144 , pp. 886-896
    • Yosef, N.1    Regev, A.2
  • 72
    • 57349192792 scopus 로고    scopus 로고
    • Motivations and methods for analyzing pulsatile hormone secretion
    • Veldhuis, J. D., Keenan, D. M. & Pincus, S. M. Motivations and methods for analyzing pulsatile hormone secretion. Endocr. Rev. 29, 823-864 (2008).
    • (2008) Endocr. Rev. , vol.29 , pp. 823-864
    • Veldhuis, J.D.1    Keenan, D.M.2    Pincus, S.M.3
  • 73
    • 69949126005 scopus 로고    scopus 로고
    • Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription
    • Stavreva, D. A. et al. Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription. Nature Cell Biol. 11, 1093-1102 (2009).
    • (2009) Nature Cell Biol. , vol.11 , pp. 1093-1102
    • Stavreva, D.A.1
  • 75
    • 66349107101 scopus 로고    scopus 로고
    • Harmonics of circadian gene transcription in mammals
    • Hughes, M. E. et al. Harmonics of circadian gene transcription in mammals. PLoS. Genet. 5, e1000442 (2009).
    • (2009) PLoS. Genet. , vol.5
    • Hughes, M.E.1
  • 76
    • 75849136095 scopus 로고    scopus 로고
    • Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression
    • Vollmers, C. et al. Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression. Proc. Natl Acad. Sci. USA 106, 21453-21458 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 21453-21458
    • Vollmers, C.1
  • 77
    • 80053306159 scopus 로고    scopus 로고
    • Nuclear receptor DHR4 controls the timing of steroid hormone pulses during Drosophila development
    • Ou, Q., Magico, A. & King-Jones, K. Nuclear receptor DHR4 controls the timing of steroid hormone pulses during Drosophila development. PLoS. Biol. 9, e1001160 (2011).
    • (2011) PLoS. Biol. , vol.9
    • Ou, Q.1    Magico, A.2    King-Jones, K.3
  • 78
    • 84865536748 scopus 로고    scopus 로고
    • Long-term model predictive control of gene expression at the population and single-cell levels
    • Uhlendorf, J. et al. Long-term model predictive control of gene expression at the population and single-cell levels. Proc. Natl Acad. Sci. USA 109, 14271-14276 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 14271-14276
    • Uhlendorf, J.1
  • 79
    • 33645312379 scopus 로고    scopus 로고
    • Circuitry of nuclear factor κb signaling
    • Hoffmann, A. & Baltimore, D. Circuitry of nuclear factor κB signaling. Immunol. Rev. 210, 171-186 (2006).
    • (2006) Immunol. Rev. , vol.210 , pp. 171-186
    • Hoffmann, A.1    Baltimore, D.2
  • 80
    • 70349687069 scopus 로고    scopus 로고
    • Sustained oscillations of NF-κB produce distinct genome scanning and gene expression profiles
    • Sung, M. H. et al. Sustained oscillations of NF-κB produce distinct genome scanning and gene expression profiles. PLoS ONE 4, e7163 (2009).
    • (2009) PLoS ONE , vol.4
    • Sung, M.H.1
  • 81
    • 7444254365 scopus 로고    scopus 로고
    • Oscillations in NF-κB signaling control the dynamics of gene expression
    • Nelson, D. E. et al. Oscillations in NF-κB signaling control the dynamics of gene expression. Science 306, 704-708 (2004).
    • (2004) Science , vol.306 , pp. 704-708
    • Nelson, D.E.1
  • 82
    • 0842332406 scopus 로고    scopus 로고
    • Dynamics of the p53-Mdm2 feedback loop in individual cells
    • Lahav, G. et al. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nature Genet. 36, 147-150 (2004).
    • (2004) Nature Genet. , vol.36 , pp. 147-150
    • Lahav, G.1
  • 83
    • 64849104716 scopus 로고    scopus 로고
    • Pulsatile stimulation determines timing and specificity of NF-κB-dependent transcription
    • Ashall, L. et al. Pulsatile stimulation determines timing and specificity of NF-κB-dependent transcription. Science 324, 242-246 (2009).
    • (2009) Science , vol.324 , pp. 242-246
    • Ashall, L.1
  • 84
    • 84862270480 scopus 로고    scopus 로고
    • P53 dynamics control cell fate
    • Purvis, J. E. et al. p53 dynamics control cell fate. Science 336, 1440-1444 (2012).
    • (2012) Science , vol.336 , pp. 1440-1444
    • Purvis, J.E.1
  • 86
    • 52949098296 scopus 로고    scopus 로고
    • Frequency-modulated nuclear localization bursts coordinate gene regulation
    • Cai, L., Dalal, C. K. & Elowitz, M. B. Frequency-modulated nuclear localization bursts coordinate gene regulation. Nature 455, 485-490 (2008).
    • (2008) Nature , vol.455 , pp. 485-490
    • Cai, L.1    Dalal, C.K.2    Elowitz, M.B.3
  • 87
    • 84855424553 scopus 로고    scopus 로고
    • Signal-dependent dynamics of transcription factor translocation controls gene expression
    • Hao, N. & O'Shea, E. K. Signal-dependent dynamics of transcription factor translocation controls gene expression. Nature Struct. Mol. Biol. 19, 31-39 (2012).
    • (2012) Nature Struct. Mol. Biol. , vol.19 , pp. 31-39
    • Hao, N.1    O'Shea, E.K.2
  • 89
    • 12144289862 scopus 로고    scopus 로고
    • From silencing to gene expression: Real-time analysis in single cells
    • Janicki, S. M. et al. From silencing to gene expression: real-time analysis in single cells. Cell 116, 683-698 (2004).
    • (2004) Cell , vol.116 , pp. 683-698
    • Janicki, S.M.1
  • 90
    • 28944434119 scopus 로고    scopus 로고
    • Real-time kinetics of gene activity in individual bacteria
    • Golding, I., Paulsson, J., Zawilski, S. M. & Cox, E. C. Real-time kinetics of gene activity in individual bacteria. Cell 123, 1025-1036 (2005).
    • (2005) Cell , vol.123 , pp. 1025-1036
    • Golding, I.1    Paulsson, J.2    Zawilski, S.M.3    Cox, E.C.4
  • 91
    • 33646591544 scopus 로고    scopus 로고
    • Transcriptional pulsing of a developmental gene
    • Chubb, J. R., Trcek, T., Shenoy, S. M. & Singer, R. H. Transcriptional pulsing of a developmental gene. Curr. Biol. 16, 1018-1025 (2006).
    • (2006) Curr. Biol. , vol.16 , pp. 1018-1025
    • Chubb, J.R.1    Trcek, T.2    Shenoy, S.M.3    Singer, R.H.4
  • 93
    • 34548507690 scopus 로고    scopus 로고
    • In vivo dynamics of RNA polymerase II transcription
    • Darzacq, X. et al. In vivo dynamics of RNA polymerase II transcription. Nature Struct. Mol. Biol. 14, 796-806 (2007).
    • (2007) Nature Struct. Mol. Biol. , vol.14 , pp. 796-806
    • Darzacq, X.1
  • 94
    • 82555179165 scopus 로고    scopus 로고
    • Origins and consequences of transcriptional discontinuity
    • Suter, D. M., Molina, N., Naef, F. & Schibler, U. Origins and consequences of transcriptional discontinuity. Curr. Opin. Cell Biol. 23, 657-662 (2011).
    • (2011) Curr. Opin. Cell Biol. , vol.23 , pp. 657-662
    • Suter, D.M.1    Molina, N.2    Naef, F.3    Schibler, U.4
  • 95
    • 58549110252 scopus 로고    scopus 로고
    • Stochastic modelling for quantitative description of heterogeneous biological systems
    • Wilkinson, D. J. Stochastic modelling for quantitative description of heterogeneous biological systems. Nature Rev. Genet. 10, 122-133 (2009).
    • (2009) Nature Rev. Genet. , vol.10 , pp. 122-133
    • Wilkinson, D.J.1
  • 96
    • 67749113808 scopus 로고    scopus 로고
    • Transcriptional regulatory circuits: Predicting numbers from alphabets
    • Kim, H. D., Shay, T., O'Shea, E. K. & Regev, A. Transcriptional regulatory circuits: predicting numbers from alphabets. Science 325, 429-432 (2009).
    • (2009) Science , vol.325 , pp. 429-432
    • Kim, H.D.1    Shay, T.2    O'Shea, E.K.3    Regev, A.4
  • 97
    • 0025127307 scopus 로고
    • The dose dependence of glucocorticoid-inducible gene expression results from changes in the number of transcriptionally active templates
    • Ko, M. S., Nakauchi, H. & Takahashi, N. The dose dependence of glucocorticoid-inducible gene expression results from changes in the number of transcriptionally active templates. EMBO J. 9, 2835-2842 (1990).
    • (1990) EMBO J. , vol.9 , pp. 2835-2842
    • Ko, M.S.1    Nakauchi, H.2    Takahashi, N.3
  • 98
    • 0028200288 scopus 로고
    • Differential steroid hormone induction of transcription from the mouse mammary tumor virus promoter
    • Archer, T. K. et al. Differential steroid hormone induction of transcription from the mouse mammary tumor virus promoter. Mol. Endocrinol. 8, 568-576 (1994).
    • (1994) Mol. Endocrinol. , vol.8 , pp. 568-576
    • Archer, T.K.1
  • 99
    • 0013537360 scopus 로고    scopus 로고
    • Dynamic behavior of transcription factors on a natural promoter in living cells
    • Becker, M. et al. Dynamic behavior of transcription factors on a natural promoter in living cells. EMBO Rep. 3, 1188-1194 (2002).
    • (2002) EMBO Rep. , vol.3 , pp. 1188-1194
    • Becker, M.1
  • 100
    • 0033637703 scopus 로고    scopus 로고
    • Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
    • Shang, Y., Hu, X., DiRenzo, J., Lazar, M. A. & Brown, M. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103, 843-852 (2000).
    • (2000) Cell , vol.103 , pp. 843-852
    • Shang, Y.1    Hu, X.2    Direnzo, J.3    Lazar, M.A.4    Brown, M.5
  • 101
    • 2642544592 scopus 로고    scopus 로고
    • Estrogen receptor-α directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter
    • Metivier, R. et al. Estrogen receptor-α directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell 115, 751-763 (2003).
    • (2003) Cell , vol.115 , pp. 751-763
    • Metivier, R.1
  • 102
    • 79955836460 scopus 로고    scopus 로고
    • A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells
    • Hah, N. et al. A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells. Cell 145, 622-634 (2011).
    • (2011) Cell , vol.145 , pp. 622-634
    • Hah, N.1
  • 103
    • 38549126635 scopus 로고    scopus 로고
    • Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter
    • Karpova, T. S. et al. Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter. Science 319, 466-469 (2008).
    • (2008) Science , vol.319 , pp. 466-469
    • Karpova, T.S.1
  • 104
    • 79955854161 scopus 로고    scopus 로고
    • An epigenetic signature for monoallelic olfactory receptor expression
    • Magklara, A. et al. An epigenetic signature for monoallelic olfactory receptor expression. Cell 145, 555-570 (2011).
    • (2011) Cell , vol.145 , pp. 555-570
    • Magklara, A.1
  • 105
    • 79955381895 scopus 로고    scopus 로고
    • Mammalian genes are transcribed with widely different bursting kinetics
    • Suter, D. M. et al. Mammalian genes are transcribed with widely different bursting kinetics. Science 332, 472-474 (2011).
    • (2011) Science , vol.332 , pp. 472-474
    • Suter, D.M.1
  • 106
    • 65249185613 scopus 로고    scopus 로고
    • Combinatorial probabilistic chromatin interactions produce transcriptional heterogeneity
    • Voss, T. C. et al. Combinatorial probabilistic chromatin interactions produce transcriptional heterogeneity. J. Cell. Sci. 122, 345-356 (2009).
    • (2009) J. Cell. Sci. , vol.122 , pp. 345-356
    • Voss, T.C.1
  • 107
    • 17844410927 scopus 로고    scopus 로고
    • Persistent synchronized oscillations in prolactin gene promoter activity in living pituitary cells
    • McFerran, D. W. et al. Persistent synchronized oscillations in prolactin gene promoter activity in living pituitary cells. Endocrinology 142, 3255-3260 (2001).
    • (2001) Endocrinology , vol.142 , pp. 3255-3260
    • McFerran, D.W.1
  • 108
    • 0036168102 scopus 로고    scopus 로고
    • PRL gene expression in individual living mammotropes displays distinct functional pulses that oscillate in a noncircadian temporal pattern
    • Shorte, S. L. et al. PRL gene expression in individual living mammotropes displays distinct functional pulses that oscillate in a noncircadian temporal pattern. Endocrinology 143, 1126-1133 (2002).
    • (2002) Endocrinology , vol.143 , pp. 1126-1133
    • Shorte, S.L.1
  • 109
    • 48649097511 scopus 로고    scopus 로고
    • Activation of estrogen receptor-α by E2 or EGF induces temporally distinct patterns of large-scale chromatin modification and mRNA transcription
    • Berno, V. et al. Activation of estrogen receptor-α by E2 or EGF induces temporally distinct patterns of large-scale chromatin modification and mRNA transcription. PLoS ONE. 3, e2286 (2008).
    • (2008) PLoS ONE. , vol.3
    • Berno, V.1
  • 110
    • 79957608918 scopus 로고    scopus 로고
    • General properties of transcriptional time series in Escherichia coli
    • So, L. H. et al. General properties of transcriptional time series in Escherichia coli. Nature Genet. 43, 554-560 (2011).
    • (2011) Nature Genet. , vol.43 , pp. 554-560
    • So, L.H.1
  • 111
    • 77952215650 scopus 로고    scopus 로고
    • Optimized localization analysis for single-molecule tracking and super-resolution microscopy
    • Mortensen, K. I., Churchman, L. S., Spudich, J. A. & Flyvbjerg, H. Optimized localization analysis for single-molecule tracking and super-resolution microscopy. Nature Methods 7, 377-381 (2010).
    • (2010) Nature Methods , vol.7 , pp. 377-381
    • Mortensen, K.I.1    Churchman, L.S.2    Spudich, J.A.3    Flyvbjerg, H.4
  • 112
    • 37349048312 scopus 로고    scopus 로고
    • Raster image correlation spectroscopy (RICS) for measuring fast protein dynamics and concentrations with a commercial laser scanning confocal microscope
    • Brown, C. M. et al. Raster image correlation spectroscopy (RICS) for measuring fast protein dynamics and concentrations with a commercial laser scanning confocal microscope. J. Microsc. 229, 78-91 (2008).
    • (2008) J. Microsc. , vol.229 , pp. 78-91
    • Brown, C.M.1
  • 113
    • 44049105523 scopus 로고    scopus 로고
    • Mapping the number of molecules and brightness in the laser scanning microscope
    • Digman, M. A., Dalal, R., Horwitz, A. F. & Gratton, E. Mapping the number of molecules and brightness in the laser scanning microscope. Biophys. J. 94, 2320-2332 (2008).
    • (2008) Biophys. J. , vol.94 , pp. 2320-2332
    • Digman, M.A.1    Dalal, R.2    Horwitz, A.F.3    Gratton, E.4
  • 114
    • 80255137569 scopus 로고    scopus 로고
    • Probing protein heterogeneity in the plasma membrane using PALM and pair correlation analysis
    • Sengupta, P. et al. Probing protein heterogeneity in the plasma membrane using PALM and pair correlation analysis. Nature Methods 8, 969-975 (2011).
    • (2011) Nature Methods , vol.8 , pp. 969-975
    • Sengupta, P.1
  • 115
    • 34547633677 scopus 로고    scopus 로고
    • Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing
    • Robertson, G. et al. Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing. Nature Methods 4, 651-657 (2007).
    • (2007) Nature Methods , vol.4 , pp. 651-657
    • Robertson, G.1
  • 116
    • 84879387751 scopus 로고    scopus 로고
    • Genome-wide measurement of protein-DNA binding dynamics using competition ChIP
    • Lickwar, C. R., Mueller, F. & Lieb, J. D. Genome-wide measurement of protein-DNA binding dynamics using competition ChIP. Nature Protoc. 8, 1337-1353 (2013).
    • (2013) Nature Protoc. , vol.8 , pp. 1337-1353
    • Lickwar, C.R.1    Mueller, F.2    Lieb, J.D.3
  • 118
    • 16644398332 scopus 로고    scopus 로고
    • UV laser cross-linking: A real-time assay to study dynamic protein/DNA interactions during chromatin remodeling
    • Nagaich, A. K. & Hager, G. L. UV laser cross-linking: a real-time assay to study dynamic protein/DNA interactions during chromatin remodeling. Sci. STKE 256, L13 (2004).
    • (2004) Sci. STKE , vol.256
    • Nagaich, A.K.1    Hager, G.L.2
  • 119
    • 0023646729 scopus 로고
    • Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors
    • Becker, P. B., Ruppert, S. & Schutz, G. Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors. Cell 51, 435-443 (1987).
    • (1987) Cell , vol.51 , pp. 435-443
    • Becker, P.B.1    Ruppert, S.2    Schutz, G.3
  • 120
    • 13844298835 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling revealed by FRAP and FLIP technologies
    • Koster, M., Frahm, T. & Hauser, H. Nucleocytoplasmic shuttling revealed by FRAP and FLIP technologies. Curr. Opin. Biotechnol. 16, 28-34 (2005).
    • (2005) Curr. Opin. Biotechnol. , vol.16 , pp. 28-34
    • Koster, M.1    Frahm, T.2    Hauser, H.3
  • 122
    • 84862961635 scopus 로고    scopus 로고
    • Monitoring protein interactions in living cells with fluorescence lifetime imaging microscopy
    • Sun, Y., Hays, N. M., Periasamy, A., Davidson, M. W. & Day, R. N. Monitoring protein interactions in living cells with fluorescence lifetime imaging microscopy. Methods Enzymol. 504, 371-391 (2012).
    • (2012) Methods Enzymol. , vol.504 , pp. 371-391
    • Sun, Y.1    Hays, N.M.2    Periasamy, A.3    Davidson, M.W.4    Day, R.N.5
  • 123
    • 84934434809 scopus 로고    scopus 로고
    • Monitoring dynamic binding of chromatin proteins in vivo by single-molecule tracking
    • Mazza, D., Ganguly, S. & McNally, J. G. Monitoring dynamic binding of chromatin proteins in vivo by single-molecule tracking. Methods Mol. Biol. 1042, 117-137 (2013).
    • (2013) Methods Mol. Biol. , vol.1042 , pp. 117-137
    • Mazza, D.1    Ganguly, S.2    McNally, J.G.3
  • 124
    • 79951703348 scopus 로고    scopus 로고
    • Revisiting the central dogma one molecule at a time
    • Bustamante, C., Cheng, W. & Mejia, Y. X. Revisiting the central dogma one molecule at a time. Cell 144, 480-497 (2011).
    • (2011) Cell , vol.144 , pp. 480-497
    • Bustamante, C.1    Cheng, W.2    Mejia, Y.X.3


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