메뉴 건너뛰기




Volumn 13, Issue 15, 2004, Pages 1563-1575

Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; CELL RECEPTOR; COMPLEMENTARY DNA; GLUTATHIONE TRANSFERASE; HOMEODOMAIN PROTEIN; LEUCINE ZIPPER PROTEIN; PROTEIN NR1D1; PROTEIN NR2E3; UNCLASSIFIED DRUG;

EID: 4344665205     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddh173     Document Type: Article
Times cited : (214)

References (61)
  • 2
    • 0035257731 scopus 로고    scopus 로고
    • Vertebrate neural cell-fate determination: Lessons from the retina
    • Livesey, F.J. and Cepko, C.L. (2001) Vertebrate neural cell-fate determination: lessons from the retina. Nat. Rev. Neurosci., 2, 109-118.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 109-118
    • Livesey, F.J.1    Cepko, C.L.2
  • 3
    • 0036155692 scopus 로고    scopus 로고
    • Generating neuronal diversity in the retina: One for nearly all
    • Marquardt, T. and Gruss, P. (2002) Generating neuronal diversity in the retina: one for nearly all. Trends Neurosci., 25, 32-38.
    • (2002) Trends Neurosci. , vol.25 , pp. 32-38
    • Marquardt, T.1    Gruss, P.2
  • 4
    • 0345735939 scopus 로고    scopus 로고
    • Importance of intrinsic mechanisms in cell fate decisions in the developing rat retina
    • Cayouette, M., Barres, B.A. and Raff, M. (2003) Importance of intrinsic mechanisms in cell fate decisions in the developing rat retina. Neuron, 40, 897-904.
    • (2003) Neuron , vol.40 , pp. 897-904
    • Cayouette, M.1    Barres, B.A.2    Raff, M.3
  • 5
    • 0026663540 scopus 로고
    • Differentiation requires continuous active control
    • Blau, H.M. (1992) Differentiation requires continuous active control. Annu. Rev. Biochem., 61, 1213-1230.
    • (1992) Annu. Rev. Biochem. , vol.61 , pp. 1213-1230
    • Blau, H.M.1
  • 6
    • 0042357381 scopus 로고    scopus 로고
    • Progress toward understanding the genetic and biochemical mechanisms of inherited photoreceptor degenerations
    • Pacione, L.R., Szego, M.J., Ikeda, S., Nishina, P.M. and McInnes, R.R. (2003) Progress toward understanding the genetic and biochemical mechanisms of inherited photoreceptor degenerations. Annu. Rev. Neurosci., 26, 657-700.
    • (2003) Annu. Rev. Neurosci. , vol.26 , pp. 657-700
    • Pacione, L.R.1    Szego, M.J.2    Ikeda, S.3    Nishina, P.M.4    McInnes, R.R.5
  • 7
    • 0033399668 scopus 로고    scopus 로고
    • Molecular genetics of human retinal disease
    • Rattner, A., Sun, H. and Nathans, J. (1999) Molecular genetics of human retinal disease. Annu. Rev. Genet., 33, 89-131.
    • (1999) Annu. Rev. Genet. , vol.33 , pp. 89-131
    • Rattner, A.1    Sun, H.2    Nathans, J.3
  • 11
    • 0344442834 scopus 로고    scopus 로고
    • Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development
    • Nishida, A., Furukawa, A., Koike, C., Tano, Y., Aizawa, S., Matsuo, I. and Furukawa, T. (2003) Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development. Nat. Neurosci., 6, 1255-1263.
    • (2003) Nat. Neurosci. , vol.6 , pp. 1255-1263
    • Nishida, A.1    Furukawa, A.2    Koike, C.3    Tano, Y.4    Aizawa, S.5    Matsuo, I.6    Furukawa, T.7
  • 17
    • 0032749223 scopus 로고    scopus 로고
    • Retinopathy and attenuated circadian entrainment in Crx-deficient mice
    • Furukawa, T., Morrow, E.M., Li, T., Davis, F.C. and Cepko, C.L. (1999) Retinopathy and attenuated circadian entrainment in Crx-deficient mice. Nat. Genet., 23, 466-470.
    • (1999) Nat. Genet. , vol.23 , pp. 466-470
    • Furukawa, T.1    Morrow, E.M.2    Li, T.3    Davis, F.C.4    Cepko, C.L.5
  • 18
    • 0034703019 scopus 로고    scopus 로고
    • The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation
    • Mitton, K.P., Swain, P.K., Chen, S., Xu, S., Zack, D.J. and Swaroop, A. (2000) The leucine zipper of NRL interacts with the CRX homeodomain. A possible mechanism of transcriptional synergy in rhodopsin regulation. J. Biol. Chem., 275, 29794-29799.
    • (2000) J. Biol. Chem. , vol.275 , pp. 29794-29799
    • Mitton, K.P.1    Swain, P.K.2    Chen, S.3    Xu, S.4    Zack, D.J.5    Swaroop, A.6
  • 19
    • 0030064117 scopus 로고    scopus 로고
    • The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression
    • Rehemtulla, A., Warwar, R., Kumar, R., Ji, X., Zack, D.J. and Swaroop, A. (1996) The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression. Proc. Natl Acad. Sci. USA, 93, 191-195.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 191-195
    • Rehemtulla, A.1    Warwar, R.2    Kumar, R.3    Ji, X.4    Zack, D.J.5    Swaroop, A.6
  • 20
    • 0030781996 scopus 로고    scopus 로고
    • Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes
    • Chen, S., Wang, Q.L., Nie, Z., Sun, H., Lennon, G., Copeland, N.G., Gilbert, D.J., Jenkins, N.A. and Zack, D.J. (1997) Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes. Neuron, 19, 1017-1030.
    • (1997) Neuron , vol.19 , pp. 1017-1030
    • Chen, S.1    Wang, Q.L.2    Nie, Z.3    Sun, H.4    Lennon, G.5    Copeland, N.G.6    Gilbert, D.J.7    Jenkins, N.A.8    Zack, D.J.9
  • 21
    • 0035860776 scopus 로고    scopus 로고
    • Nrl and Sp nuclear proteins mediate transcription of rod-specific cGMP-phosphodiesterase beta-subunit gene: Involvement of multiple response elements
    • Lerner, L.E., Gribanova, Y.E., Ji, M., Knox, B.E. and Farber, D.B. (2001) Nrl and Sp nuclear proteins mediate transcription of rod-specific cGMP-phosphodiesterase beta-subunit gene: involvement of multiple response elements. J. Biol. Chem., 276, 34999-35007.
    • (2001) J. Biol. Chem. , vol.276 , pp. 34999-35007
    • Lerner, L.E.1    Gribanova, Y.E.2    Ji, M.3    Knox, B.E.4    Farber, D.B.5
  • 22
    • 2442425295 scopus 로고    scopus 로고
    • Functional analysis of the rod photoreceptor cGMP phosphodiesterase α-subunit gene promoter: Nrl and Crx are required for full transcriptional actility
    • Pittler, S.J., Zhang, Y., Chen, S., Mears, A.J., Zack, D.J., Ren, Z., Swain, P.K., Yao, S., Swaroop, A. and White, J.B. (2004) Functional analysis of the rod photoreceptor cGMP phosphodiesterase α-subunit gene promoter: Nrl and Crx are required for full transcriptional actility. J. Biol. Chem., 279, 19800-19807.
    • (2004) J. Biol. Chem. , vol.279 , pp. 19800-19807
    • Pittler, S.J.1    Zhang, Y.2    Chen, S.3    Mears, A.J.4    Zack, D.J.5    Ren, Z.6    Swain, P.K.7    Yao, S.8    Swaroop, A.9    White, J.B.10
  • 27
    • 0032929074 scopus 로고    scopus 로고
    • Leber congenital amaurosis caused by a homozygous mutation (R90W) in the homeodomain of the retinal transcription factor CRX: Direct evidence for the involvement of CRX in the development of photoreceptor function
    • Swaroop, A., Wang, Q.L., Wu, W., Cook, J., Coats, C., Xu, S., Chen, S., Zack, D.J. and Sieving, P.A. (1999) Leber congenital amaurosis caused by a homozygous mutation (R90W) in the homeodomain of the retinal transcription factor CRX: direct evidence for the involvement of CRX in the development of photoreceptor function. Hum. Mol. Genet., 8, 299-305.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 299-305
    • Swaroop, A.1    Wang, Q.L.2    Wu, W.3    Cook, J.4    Coats, C.5    Xu, S.6    Chen, S.7    Zack, D.J.8    Sieving, P.A.9
  • 28
    • 0035206015 scopus 로고    scopus 로고
    • Dominant Leber congenital amaurosis, cone-rod degeneration, and retinitis pigmentosa caused by mutant versions of the transcription factor CRX
    • Rivolta, C., Berson, E.L. and Dryja, T.P. (2001) Dominant Leber congenital amaurosis, cone-rod degeneration, and retinitis pigmentosa caused by mutant versions of the transcription factor CRX Hum. Mutat., 18, 488-498.
    • (2001) Hum. Mutat. , vol.18 , pp. 488-498
    • Rivolta, C.1    Berson, E.L.2    Dryja, T.P.3
  • 32
    • 0141722455 scopus 로고    scopus 로고
    • Shared mutations in NR2E3 in enhanced S-cone syndrome, Goldmann-Favre syndrome, and many cases of clumped pigmentary retinal degeneration
    • Sharon, D., Sandberg, M.A., Caruso, R.C., Berson, E.L. and Dryja, T.P. (2003) Shared mutations in NR2E3 in enhanced S-cone syndrome, Goldmann-Favre syndrome, and many cases of clumped pigmentary retinal degeneration. Arch. Ophthalmol., 121, 1316-1323.
    • (2003) Arch. Ophthalmol. , vol.121 , pp. 1316-1323
    • Sharon, D.1    Sandberg, M.A.2    Caruso, R.C.3    Berson, E.L.4    Dryja, T.P.5
  • 34
    • 0035421442 scopus 로고    scopus 로고
    • Excess cone cell proliferation due to lack of a functional NR2E3 causes retinal dysplasia and degeneration in rd7/rd7 mice
    • Haider, N.B., Naggert, J.K. and Nishina, P.M. (2001) Excess cone cell proliferation due to lack of a functional NR2E3 causes retinal dysplasia and degeneration in rd7/rd7 mice. Hum. Mol. Genet., 10, 1619-1626.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 1619-1626
    • Haider, N.B.1    Naggert, J.K.2    Nishina, P.M.3
  • 38
    • 0037440697 scopus 로고    scopus 로고
    • Interaction of retinal bZIP transcription factor NRL with Flt3-interacting zinc-finger protein Fiz1: Possible role of Fiz1 as a transcriptional repressor
    • Mitton, K.P., Swain, P.K., Khanna, H., Dowd, M., Apel, I.J. and Swaroop, A. (2003) Interaction of retinal bZIP transcription factor NRL with Flt3-interacting zinc-finger protein Fiz1: possible role of Fiz1 as a transcriptional repressor. Hum. Mol. Genet., 12, 365-373.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 365-373
    • Mitton, K.P.1    Swain, P.K.2    Khanna, H.3    Dowd, M.4    Apel, I.J.5    Swaroop, A.6
  • 39
    • 0029902034 scopus 로고    scopus 로고
    • Missense mutation in the gene encoding the alpha subunit of rod transducin in the Nougaret form of congenital stationary night blindness
    • Dryja, T.P., Hahn, L.B., Reboul, T. and Arnaud, B. (1996) Missense mutation in the gene encoding the alpha subunit of rod transducin in the Nougaret form of congenital stationary night blindness. Nat. Genet., 13, 358-360.
    • (1996) Nat. Genet. , vol.13 , pp. 358-360
    • Dryja, T.P.1    Hahn, L.B.2    Reboul, T.3    Arnaud, B.4
  • 40
    • 0032498230 scopus 로고    scopus 로고
    • The enhanceosome and transcriptional synergy
    • Carey, M. (1998) The enhanceosome and transcriptional synergy. Cell, 92, 5-8.
    • (1998) Cell , vol.92 , pp. 5-8
    • Carey, M.1
  • 41
    • 0142137250 scopus 로고    scopus 로고
    • The eukaryotic transcriptional machinery: Complexities and mechanisms unforeseen
    • Roeder, R.G. (2003) The eukaryotic transcriptional machinery: complexities and mechanisms unforeseen. Nat. Med., 9, 1239-1244.
    • (2003) Nat. Med. , vol.9 , pp. 1239-1244
    • Roeder, R.G.1
  • 42
    • 0024522826 scopus 로고
    • A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit
    • Lazar, M.A., Hodin, R.A., Darling, D.S. and Chin, W.W. (1989) A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit. Mol. Cell Biol., 9, 1128-1136.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 1128-1136
    • Lazar, M.A.1    Hodin, R.A.2    Darling, D.S.3    Chin, W.W.4
  • 43
    • 0034010922 scopus 로고    scopus 로고
    • Increased cell death and delayed development in the cerebellum of mice lacking the rev-erbA(alpha) orphan receptor
    • Chomez, P., Neveu, I., Mansen, A., Kiesler, E., Larsson, L., Vennstrom, B. and Arenas, E. (2000) Increased cell death and delayed development in the cerebellum of mice lacking the rev-erbA(alpha) orphan receptor. Development, 127, 1489-1498.
    • (2000) Development , vol.127 , pp. 1489-1498
    • Chomez, P.1    Neveu, I.2    Mansen, A.3    Kiesler, E.4    Larsson, L.5    Vennstrom, B.6    Arenas, E.7
  • 44
    • 0028825233 scopus 로고
    • Ligands of steroid/thyroid receptors induce cone photoreceptors in vertebrate retina
    • Kelley, M.W., Turner, J.K. and Reh, T.A. (1995) Ligands of steroid/thyroid receptors induce cone photoreceptors in vertebrate retina. Development, 121, 3777-3785.
    • (1995) Development , vol.121 , pp. 3777-3785
    • Kelley, M.W.1    Turner, J.K.2    Reh, T.A.3
  • 45
    • 0037178861 scopus 로고    scopus 로고
    • Orphan nuclear hormone receptor Rev-erbα regulates the human apolipoprotein CIII promoter
    • Coste, H. and Rodriguez, J.C. (2002) Orphan nuclear hormone receptor Rev-erbα regulates the human apolipoprotein CIII promoter. J. Biol. Chem., 277, 27120-27129.
    • (2002) J. Biol. Chem. , vol.277 , pp. 27120-27129
    • Coste, H.1    Rodriguez, J.C.2
  • 46
    • 1842328569 scopus 로고    scopus 로고
    • Differential regulation of the N-myc proto-oncogene by RORα and RVR, two orphan members of the superfamily of nuclear hormone receptors
    • Dussault, I. and Giguere, V. (1997) Differential regulation of the N-myc proto-oncogene by RORα and RVR, two orphan members of the superfamily of nuclear hormone receptors. Mol. Cell. Biol., 17, 1860-1867.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1860-1867
    • Dussault, I.1    Giguere, V.2
  • 47
    • 0036591360 scopus 로고    scopus 로고
    • Rev-erbalpha gene expression in the mouse brain with special emphasis on its circadian profiles in the suprachiasmatic nucleus
    • Onishi, H., Yamaguchi, S., Yagita, K., Ishida, Y., Dong, X., Kimura, H., Jing, Z., Ohara, H. and Okamura, H. (2002) Rev-erbalpha gene expression in the mouse brain with special emphasis on its circadian profiles in the suprachiasmatic nucleus. J. Neurosci. Res., 68, 551-557.
    • (2002) J. Neurosci. Res. , vol.68 , pp. 551-557
    • Onishi, H.1    Yamaguchi, S.2    Yagita, K.3    Ishida, Y.4    Dong, X.5    Kimura, H.6    Jing, Z.7    Ohara, H.8    Okamura, H.9
  • 48
    • 0037426839 scopus 로고    scopus 로고
    • Rhythmic historic acetylation underlies transcription in the mammalian circadian clock
    • Etchegaray, J., Lee, C., Wade, P.A. and Reppert, S. (2003) Rhythmic historic acetylation underlies transcription in the mammalian circadian clock. Nature, 421, 177-182.
    • (2003) Nature , vol.421 , pp. 177-182
    • Etchegaray, J.1    Lee, C.2    Wade, P.A.3    Reppert, S.4
  • 49
    • 0017297815 scopus 로고
    • Rod outer segment disk shedding in rat retina: Relationship to cyclic lighting
    • LaVail, M.M. (1976) Rod outer segment disk shedding in rat retina: relationship to cyclic lighting. Science, 194, 1071-1074.
    • (1976) Science , vol.194 , pp. 1071-1074
    • LaVail, M.M.1
  • 50
    • 0023687723 scopus 로고
    • Opsin, G-protein and 48-kDa protein in normal and rd mouse retinas: Developmental expression of mRNAs and proteins and light/dark cycling of mRNAs
    • Bowes, C., van Veen, T. and Farber, D.B. (1988) Opsin, G-protein and 48-kDa protein in normal and rd mouse retinas: developmental expression of mRNAs and proteins and light/dark cycling of mRNAs. Exp. Eye Res., 47, 369-390.
    • (1988) Exp. Eye Res. , vol.47 , pp. 369-390
    • Bowes, C.1    van Veen, T.2    Farber, D.B.3
  • 52
    • 0029150186 scopus 로고
    • The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat
    • Harding, H.P. and Lazar, M.A. (1995) The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat. Mol. Cell. Biol., 15, 4791-4802.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4791-4802
    • Harding, H.P.1    Lazar, M.A.2
  • 53
    • 4344688220 scopus 로고
    • Nuclear recepfor/AP-1 interaction
    • Pfahl, M. (1993) Nuclear recepfor/AP-1 interaction. Endocr. Rev., 14, 615-618.
    • (1993) Endocr. Rev. , vol.14 , pp. 615-618
    • Pfahl, M.1
  • 54
    • 0025188132 scopus 로고
    • Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
    • Yang-Yen, H.F., Chambard, J.C., Sun, Y.L., Smeal, T., Schmidt, T.J., Drouin, J. and Karin, M. (1990) Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction Cell, 62, 1205-1215.
    • (1990) Cell , vol.62 , pp. 1205-1215
    • Yang-Yen, H.F.1    Chambard, J.C.2    Sun, Y.L.3    Smeal, T.4    Schmidt, T.J.5    Drouin, J.6    Karin, M.7
  • 55
    • 0025081214 scopus 로고
    • Transcription factor interactions: Selectors of positive or negative regulation from a single DNA element
    • Diamond, M.I., Miner, J.N., Yoshinaga, S.K. and Yamamoto, K.R. (1990) Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. Science, 249, 1266-1272.
    • (1990) Science , vol.249 , pp. 1266-1272
    • Diamond, M.I.1    Miner, J.N.2    Yoshinaga, S.K.3    Yamamoto, K.R.4
  • 56
    • 0027662103 scopus 로고
    • Hetero- and homodimeric receptors in thyroid hormone and vitamin A action
    • Zhang, X. and Pfahl, M. (1993) Hetero- and homodimeric receptors in thyroid hormone and vitamin A action. Receptor, 3, 183-191.
    • (1993) Receptor , vol.3 , pp. 183-191
    • Zhang, X.1    Pfahl, M.2
  • 58
    • 0037093507 scopus 로고    scopus 로고
    • Three habits of highly effective signaling pathways: Principles of transcriptional control by developmental cell signaling
    • Barolo, S. and Posakony, J.W. (2002) Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling. Genes Dev., 16, 1167-1181.
    • (2002) Genes Dev. , vol.16 , pp. 1167-1181
    • Barolo, S.1    Posakony, J.W.2
  • 59
    • 0033592987 scopus 로고    scopus 로고
    • Retina-specific nuclear receptor: A potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Müller glial cells
    • Chen, F., Figueroa, D.J., Marmorstein, A.D., Zhang, Q., Petrukhin, K., Caskey, C.T., Austin C.P. (1999) Retina-specific nuclear receptor: A potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Müller glial cells. Proc. Natl Acad. Sci. USA, 96, 15149-15154.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 15149-15154
    • Chen, F.1    Figueroa, D.J.2    Marmorstein, A.D.3    Zhang, Q.4    Petrukhin, K.5    Caskey, C.T.6    Austin, C.P.7
  • 60
    • 0022571973 scopus 로고
    • Differential immunogold-dextran labeling of bovine and frog rod and cone cells using monoclonal antibodies against bovine rhodopsin
    • Hicks, D. and Molday, R.S. (1986) Differential immunogold-dextran labeling of bovine and frog rod and cone cells using monoclonal antibodies against bovine rhodopsin. Exp. Eye Res., 42, 55-71.
    • (1986) Exp. Eye Res. , vol.42 , pp. 55-71
    • Hicks, D.1    Molday, R.S.2
  • 61
    • 0038825621 scopus 로고    scopus 로고
    • GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina
    • Zhu, X., Brown, B., Li, A., Mears, A.J., Swaroop, A. and Craft, C.M. (2003) GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina. J. Neurosci., 23, 6152-6160.
    • (2003) J. Neurosci. , vol.23 , pp. 6152-6160
    • Zhu, X.1    Brown, B.2    Li, A.3    Mears, A.J.4    Swaroop, A.5    Craft, C.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.