메뉴 건너뛰기




Volumn 12, Issue 11, 2013, Pages 1745-1761

Rat retinal transcriptome: Effects of aging and AMD-like retinopathy

Author keywords

Age related macular degeneration; Aging; OXYS rats; Retinal transcriptome; RNA Seq

Indexed keywords

CALCIUM; RETINAL; TRANSCRIPTOME;

EID: 84878551469     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.24825     Document Type: Article
Times cited : (62)

References (117)
  • 1
    • 85027939027 scopus 로고    scopus 로고
    • Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks
    • PMID: 22364233
    • Newman AM, Gallo NB, Hancox LS, Miller NJ, Radeke CM, Maloney MA, et al. Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks. Genome Med 2012; 4:16; PMID:22364233; http://dx.doi.org/10.1186/gm315
    • (2012) Genome Med , vol.4 , pp. 16
    • Newman, A.M.1    Gallo, N.B.2    Hancox, L.S.3    Miller, N.J.4    Radeke, C.M.5    Maloney, M.A.6
  • 2
    • 84873333444 scopus 로고    scopus 로고
    • Genetic mechanisms and age-related macular degeneration: Common variants, rare variants, copy number variations, epigenetics, and mitochondrial genetics
    • PMID: 23244519
    • Liu MM, Chan CC, Tuo J. Genetic mechanisms and age-related macular degeneration: common variants, rare variants, copy number variations, epigenetics, and mitochondrial genetics. Hum Genomics 2012; 6:13; PMID:23244519; http://dx.doi.org/10.1186/1479-7364-6-13
    • (2012) Hum Genomics , vol.6 , pp. 13
    • Liu, M.M.1    Chan, C.C.2    Tuo, J.3
  • 3
    • 84866494334 scopus 로고    scopus 로고
    • Prospective treatment of age-related diseases by slowing down aging
    • PMID: 22841821
    • Blagosklonny MV. Prospective treatment of age-related diseases by slowing down aging. Am J Pathol 2012; 181:1142-6; PMID:22841821; http://dx.doi. org/10.1016/j.ajpath.2012.06.024
    • (2012) Am J Pathol , vol.181 , pp. 1142-1146
    • Blagosklonny, M.V.1
  • 4
    • 74549205329 scopus 로고    scopus 로고
    • Validation of anti-aging drugs by treating age-related diseases
    • PMID: 20157517
    • Blagosklonny MV. Validation of anti-aging drugs by treating age-related diseases. Aging (Albany NY) 2009; 1:281-8; PMID:20157517
    • (2009) Aging (Albany NY) , vol.1 , pp. 281-288
    • Blagosklonny, M.V.1
  • 5
    • 80052084689 scopus 로고    scopus 로고
    • MTOR pathway activation in age-related retinal disease
    • PMID: 21483039
    • Zhao C, Vollrath D. mTOR pathway activation in age-related retinal disease. Aging (Albany NY) 2011; 3:346-7; PMID:21483039
    • (2011) Aging (Albany NY) , vol.3 , pp. 346-347
    • Zhao, C.1    Vollrath, D.2
  • 6
    • 79956014865 scopus 로고    scopus 로고
    • The purpose of the HIF-1/PHD feedback loop: To limit mTOR-induced HIF-1
    • PMID: 21521942
    • Demidenko ZN, Blagosklonny MV. The purpose of the HIF-1/PHD feedback loop: to limit mTOR-induced HIF-1. Cell Cycle 2011; 10:1557-62; PMID:21521942; http://dx.doi.org/10.4161/cc.10.10.15789
    • (2011) Cell Cycle , vol.10 , pp. 1557-1562
    • Demidenko, Z.N.1    Blagosklonny, M.V.2
  • 7
    • 84873633910 scopus 로고    scopus 로고
    • Genetics of longevity in model organisms: Debates and paradigm shifts
    • PMID: 23190075
    • Gems D, Partridge L. Genetics of longevity in model organisms: debates and paradigm shifts. Annu Rev Physiol 2013; 75:621-44; PMID:23190075; http://dx.doi.org/10.1146/annurev-physiol-030212-183712
    • (2013) Annu Rev Physiol , vol.75 , pp. 621-644
    • Gems, D.1    Partridge, L.2
  • 8
    • 84855518671 scopus 로고    scopus 로고
    • A new path to longevity
    • PMID: 22279832
    • Stipp D. A new path to longevity. Sci Am 2012; 306:32-9; PMID:22279832; http://dx.doi.org/10.1038/scientificamerican0112-32
    • (2012) Sci Am , vol.306 , pp. 32-39
    • Stipp, D.1
  • 9
    • 84874801912 scopus 로고    scopus 로고
    • Answering the ultimate question what is the proximal cause of aging
    • PMID: 23425777
    • Blagosklonny MV. Answering the ultimate question what is the proximal cause of aging. Aging (Albany NY) 2012; 4:861-77; PMID:23425777
    • (2012) Aging (Albany NY) , vol.4 , pp. 861-877
    • Blagosklonny, M.V.1
  • 10
    • 84879513284 scopus 로고    scopus 로고
    • Alternative perspectives on aging in caenorhabditis elegans: Reactive oxygen species or hyperfunction?
    • PMID: 22870907
    • Gems D, Guardia YD. Alternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction? Antioxid Redox Signal 2012; PMID:22870907; http://dx.doi.org/10.1089/ars.2012.4840
    • (2012) Antioxid Redox Signal
    • Gems, D.1    Guardia, Y.D.2
  • 11
    • 84856646656 scopus 로고    scopus 로고
    • Accelerated aging syndromes, are they relevant to normal human aging?
    • PMID: 21931180
    • Dreesen O, Stewart CL. Accelerated aging syndromes, are they relevant to normal human aging? Aging (Albany NY) 2011; 3:889-95; PMID:21931180
    • (2011) Aging (Albany NY) , vol.3 , pp. 889-895
    • Dreesen, O.1    Stewart, C.L.2
  • 12
    • 84859492402 scopus 로고    scopus 로고
    • Molecular links between cellular senescence, longevity and agerelated diseases -A systems biology perspective
    • PMID: 22184282
    • Tacutu R, Budovsky A, Yanai H, Fraifeld VE. Molecular links between cellular senescence, longevity and agerelated diseases -a systems biology perspective. Aging (Albany NY) 2011; 3:1178-91; PMID:22184282
    • (2011) Aging (Albany NY) , vol.3 , pp. 1178-1191
    • Tacutu, R.1    Budovsky, A.2    Yanai, H.3    Fraifeld, V.E.4
  • 13
    • 84867460485 scopus 로고    scopus 로고
    • Once again on rapamycin-induced insulin resistance and longevity: Despite of or owing to
    • PMID: 22683661
    • Blagosklonny MV. Once again on rapamycin-induced insulin resistance and longevity: despite of or owing to. Aging (Albany NY) 2012; 4:350-8; PMID:22683661
    • (2012) Aging (Albany NY) , vol.4 , pp. 350-358
    • Blagosklonny, M.V.1
  • 14
    • 84862891914 scopus 로고    scopus 로고
    • Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: Terminology for TOR-driven aging
    • PMID: 22394614
    • Blagosklonny MV. Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging. Aging (Albany NY) 2012; 4:159-65; PMID:22394614
    • (2012) Aging (Albany NY) , vol.4 , pp. 159-165
    • Blagosklonny, M.V.1
  • 15
    • 79961099905 scopus 로고    scopus 로고
    • From growing to secreting: New roles for mTOR in aging cells
    • PMID: 21720215
    • Pani G. From growing to secreting: new roles for mTOR in aging cells. Cell Cycle 2011; 10:2450-3; PMID:21720215; http://dx.doi.org/10.4161/cc.10.15. 16886
    • (2011) Cell Cycle , vol.10 , pp. 2450-2453
    • Pani, G.1
  • 16
    • 83755206847 scopus 로고    scopus 로고
    • Hormesis does not make sense except in the light of TOR-driven aging
    • PMID: 22166724
    • Blagosklonny MV. Hormesis does not make sense except in the light of TOR-driven aging. Aging (Albany NY) 2011; 3:1051-62; PMID:22166724
    • (2011) Aging (Albany NY) , vol.3 , pp. 1051-1062
    • Blagosklonny, M.V.1
  • 17
    • 84868029429 scopus 로고    scopus 로고
    • Sarcopenia, obesity, and natural killer cell immune senescence in aging: Altered cytokine levels as a common mechanism
    • PMID: 22935594
    • Lutz CT, Quinn LS. Sarcopenia, obesity, and natural killer cell immune senescence in aging: altered cytokine levels as a common mechanism. Aging (Albany NY) 2012; 4:535-46; PMID:22935594
    • (2012) Aging (Albany NY) , vol.4 , pp. 535-546
    • Lutz, C.T.1    Quinn, L.S.2
  • 18
    • 79956032310 scopus 로고    scopus 로고
    • Mitochondrial complex I: A central regulator of the aging process
    • PMID: 21471732
    • Stefanatos R, Sanz A. Mitochondrial complex I: a central regulator of the aging process. Cell Cycle 2011; 10:1528-32; PMID:21471732; http://dx.doi. org/10.4161/cc.10.10.15496
    • (2011) Cell Cycle , vol.10 , pp. 1528-1532
    • Stefanatos, R.1    Sanz, A.2
  • 19
    • 37249049422 scopus 로고    scopus 로고
    • AGEMAP: A gene expression database for aging in mice
    • PMID: 18081424
    • Zahn JM, Poosala S, Owen AB, Ingram DK, Lustig A, Carter A, et al. AGEMAP: a gene expression database for aging in mice. PLoS Genet 2007; 3:e201; PMID:18081424; http://dx.doi.org/10.1371/journal. pgen.0030201
    • (2007) PLoS Genet , vol.3
    • Zahn, J.M.1    Poosala, S.2    Owen, A.B.3    Ingram, D.K.4    Lustig, A.5    Carter, A.6
  • 20
    • 84876135874 scopus 로고    scopus 로고
    • Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome
    • Wood SH, Craig T, Li Y, Merry B, De Magalhães JP. Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome. Age (Dord)
    • Age (Dord)
    • Wood, S.H.1    Craig, T.2    Li, Y.3    Merry, B.4    De Magalhães, J.P.5
  • 21
    • 84855187277 scopus 로고    scopus 로고
    • Genome-wide transcriptome analysis in murine neural retina using high-throughput RNA sequencing
    • PMID: 22032952
    • Gamsiz ED, Ouyang Q, Schmidt M, Nagpal S, Morrow EM. Genome-wide transcriptome analysis in murine neural retina using high-throughput RNA sequencing. Genomics 2012; 99:44-51; PMID:22032952; http://dx.doi.org/10.1016/j. ygeno.2011.09.003
    • (2012) Genomics , vol.99 , pp. 44-51
    • Gamsiz, E.D.1    Ouyang, Q.2    Schmidt, M.3    Nagpal, S.4    Morrow, E.M.5
  • 22
    • 83055178312 scopus 로고    scopus 로고
    • Next-generation sequencing facilitates quantitative analysis of wild-type and Nrl(?/?) retinal transcriptomes
    • PMID: 22162623
    • Brooks MJ, Rajasimha HK, Roger JE, Swaroop A. Next-generation sequencing facilitates quantitative analysis of wild-type and Nrl(?/?) retinal transcriptomes. Mol Vis 2011; 17:3034-54; PMID:22162623
    • (2011) Mol Vis , vol.17 , pp. 3034-3054
    • Brooks, M.J.1    Rajasimha, H.K.2    Roger, J.E.3    Swaroop, A.4
  • 23
    • 84863308955 scopus 로고    scopus 로고
    • Transcriptome analysis using next generation sequencing reveals molecular signatures of diabetic retinopathy and efficacy of candidate drugs
    • PMID: 22605924
    • Kandpal RP, Rajasimha HK, Brooks MJ, Nellissery J, Wan J, Qian J, et al. Transcriptome analysis using next generation sequencing reveals molecular signatures of diabetic retinopathy and efficacy of candidate drugs. Mol Vis 2012; 18:1123-46; PMID:22605924
    • (2012) Mol Vis , vol.18 , pp. 1123-1146
    • Kandpal, R.P.1    Rajasimha, H.K.2    Brooks, M.J.3    Nellissery, J.4    Wan, J.5    Qian, J.6
  • 24
    • 84864762784 scopus 로고    scopus 로고
    • Inflammatory priming predisposes mice to age-related retinal degeneration
    • PMID: 22797304
    • Mustafi D, Maeda T, Kohno H, Nadeau JH, Palczewski K. Inflammatory priming predisposes mice to age-related retinal degeneration. J Clin Invest 2012; 122:2989-3001; PMID:22797304; http://dx.doi.org/10.1172/JCI64427
    • (2012) J Clin Invest , vol.122 , pp. 2989-3001
    • Mustafi, D.1    Maeda, T.2    Kohno, H.3    Nadeau, J.H.4    Palczewski, K.5
  • 25
    • 80052661270 scopus 로고    scopus 로고
    • Defective photoreceptor phagocytosis in a mouse model of enhanced S-cone syndrome causes progressive retinal degeneration
    • PMID: 21659555
    • Mustafi D, Kevany BM, Genoud C, Okano K, Cideciyan AV, Sumaroka A, et al. Defective photoreceptor phagocytosis in a mouse model of enhanced S-cone syndrome causes progressive retinal degeneration. FASEB J 2011; 25:3157-76; PMID:21659555; http://dx.doi.org/10.1096/fj.11-186767
    • (2011) FASEB J , vol.25 , pp. 3157-3176
    • Mustafi, D.1    Kevany, B.M.2    Genoud, C.3    Okano, K.4    Cideciyan, A.V.5    Sumaroka, A.6
  • 26
    • 45549088326 scopus 로고    scopus 로고
    • The transcriptional landscape of the yeast genome defined by RNA sequencing
    • PMID: 18451266
    • Nagalakshmi U, Wang Z, Waern K, Shou C, Raha D, Gerstein M, et al. The transcriptional landscape of the yeast genome defined by RNA sequencing. Science 2008; 320:1344-9; PMID:18451266; http://dx.doi. org/10.1126/science.1158441
    • (2008) Science , vol.320 , pp. 1344-1349
    • Nagalakshmi, U.1    Wang, Z.2    Waern, K.3    Shou, C.4    Raha, D.5    Gerstein, M.6
  • 27
    • 84864128574 scopus 로고    scopus 로고
    • Prevention of age-related macular degeneration-like retinopathy by rapamycin in rats
    • PMID: 22683466
    • Kolosova NG, Muraleva NA, Zhdankina AA, Stefanova NA, Fursova AZ, Blagosklonny MV. Prevention of age-related macular degeneration-like retinopathy by rapamycin in rats. Am J Pathol 2012; 181:472-7; PMID:22683466; http://dx.doi.org/10.1016/j. ajpath.2012.04.018
    • (2012) Am J Pathol , vol.181 , pp. 472-477
    • Kolosova, N.G.1    Muraleva, N.A.2    Zhdankina, A.A.3    Stefanova, N.A.4    Fursova, A.Z.5    Blagosklonny, M.V.6
  • 28
    • 64749099950 scopus 로고    scopus 로고
    • Clinical and morphological characteristics of chorioretinal degeneration in early aging OXYS rats
    • PMID: 19489319
    • Zhdankina AA, Fursova AZh, Logvinov SV, Kolosova NG. Clinical and morphological characteristics of chorioretinal degeneration in early aging OXYS rats. Bull Exp Biol Med 2008; 146:455-8; PMID:19489319; http://dx.doi.org/10. 1007/s10517-009-0298-4
    • (2008) Bull Exp Biol Med , vol.146 , pp. 455-458
    • Zhdankina, A.A.1    Azh, F.2    Logvinov, S.V.3    Kolosova, N.G.4
  • 30
    • 84864546287 scopus 로고    scopus 로고
    • SkQ1 slows development of age-dependent destructive processes in retina and vascular layer of eyes of wistar and OXYS rats
    • PMID: 22817465
    • Saprunova VB, Lelekova MA, Kolosova NG, Bakeeva LE. SkQ1 slows development of age-dependent destructive processes in retina and vascular layer of eyes of wistar and OXYS rats. Biochemistry (Mosc) 2012; 77:648-58; PMID:22817465; http://dx.doi. org/10.1134/S0006297912060120
    • (2012) Biochemistry (Mosc) , vol.77 , pp. 648-658
    • Saprunova, V.B.1    Lelekova, M.A.2    Kolosova, N.G.3    Bakeeva, L.E.4
  • 31
    • 77950681585 scopus 로고    scopus 로고
    • Lipofuscin granule dynamics during development of age-related macular degeneration
    • PMID: 20367599
    • Saprunova VB, Pilipenko DI, Alexeevsky AV, Fursova AZh, Kolosova NG, Bakeeva LE. Lipofuscin granule dynamics during development of age-related macular degeneration. Biochemistry (Mosc) 2010; 75:130-8; PMID:20367599; http://dx.doi.org/10.1134/S0006297910020021
    • (2010) Biochemistry (Mosc) , vol.75 , pp. 130-138
    • Saprunova, V.B.1    Pilipenko, D.I.2    Alexeevsky, A.V.3    Azh, F.4    Kolosova, N.G.5    Bakeeva, L.E.6
  • 32
    • 79958253721 scopus 로고    scopus 로고
    • Alterations of retinal pigment epithelium cause AMD-like retinopathy in senescence-accelerated OXYS rats
    • PMID: 21191149
    • Markovets AM, Saprunova VB, Zhdankina AA, Fursova AZh, Bakeeva LE, Kolosova NG. Alterations of retinal pigment epithelium cause AMD-like retinopathy in senescence-accelerated OXYS rats. Aging (Albany NY) 2011; 3:44-54; PMID:21191149
    • (2011) Aging (Albany NY) , vol.3 , pp. 44-54
    • Markovets, A.M.1    Saprunova, V.B.2    Zhdankina, A.A.3    Azh, F.4    Bakeeva, L.E.5    Kolosova, N.G.6
  • 33
    • 79959919415 scopus 로고    scopus 로고
    • Therapeutic action of the mitochondria-targeted antioxidant SkQ1 on retinopathy in OXYS rats linked with improvement of VEGF and PEDF gene expression
    • PMID: 21750722
    • Markovets AM, Fursova AZ, Kolosova NG. Therapeutic action of the mitochondria-targeted antioxidant SkQ1 on retinopathy in OXYS rats linked with improvement of VEGF and PEDF gene expression. PLoS ONE 2011; 6:e21682; PMID:21750722; http://dx.doi.org/10.1371/journal.pone.0021682
    • (2011) PLoS ONE , vol.6
    • Markovets, A.M.1    Fursova, A.Z.2    Kolosova, N.G.3
  • 34
    • 84865013696 scopus 로고    scopus 로고
    • Chemoprevention of age-related macular regeneration (AMD) with rapamycin
    • PMID: 22796653
    • Zheng XF. Chemoprevention of age-related macular regeneration (AMD) with rapamycin. Aging (Albany NY) 2012; 4:375-6; PMID:22796653
    • (2012) Aging (Albany NY) , vol.4 , pp. 375-376
    • Zheng, X.F.1
  • 35
    • 84859482962 scopus 로고    scopus 로고
    • Quantitative trait loci on chromosome 1 for cataract and AMD-like retinopathy in senescenceaccelerated OXYS rats
    • PMID: 22300709
    • Korbolina EE, Kozhevnikova OS, Stefanova NA, Kolosova NG. Quantitative trait loci on chromosome 1 for cataract and AMD-like retinopathy in senescenceaccelerated OXYS rats. Aging (Albany NY) 2012; 4:49-59; PMID:22300709
    • (2012) Aging (Albany NY) , vol.4 , pp. 49-59
    • Korbolina, E.E.1    Kozhevnikova, O.S.2    Stefanova, N.A.3    Kolosova, N.G.4
  • 36
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • PMID: 20436464
    • Trapnell C, Williams BA, Pertea G, Mortazavi A, Kwan G, van Baren MJ, et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 2010; 28:511-5; PMID:20436464; http://dx.doi.org/10.1038/nbt.1621
    • (2010) Nat Biotechnol , vol.28 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3    Mortazavi, A.4    Kwan, G.5    Van Baren, M.J.6
  • 37
    • 84866158885 scopus 로고    scopus 로고
    • Efficient experimental design and analysis strategies for the detection of differential expression using RNA-Sequencing
    • PMID: 22985019
    • Robles JA, Qureshi SE, Stephen SJ, Wilson SR, Burden CJ, Taylor JM. Efficient experimental design and analysis strategies for the detection of differential expression using RNA-Sequencing. BMC Genomics 2012; 13:484; PMID:22985019; http://dx.doi. org/10.1186/1471-2164-13-484
    • (2012) BMC Genomics , vol.13 , pp. 484
    • Robles, J.A.1    Qureshi, S.E.2    Stephen, S.J.3    Wilson, S.R.4    Burden, C.J.5    Taylor, J.M.6
  • 38
    • 77958471357 scopus 로고    scopus 로고
    • Differential expression analysis for sequence count data
    • PMID: 20979621
    • Anders S, Huber W. Differential expression analysis for sequence count data. Genome Biol 2010; 11:R106; PMID:20979621; http://dx.doi.org/10.1186/gb- 2010-11-10-r106
    • (2010) Genome Biol , vol.11
    • Anders, S.1    Huber, W.2
  • 39
    • 0037083631 scopus 로고    scopus 로고
    • Small prolinerich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth
    • PMID: 11850458
    • Bonilla IE, Tanabe K, Strittmatter SM. Small prolinerich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth. J Neurosci 2002; 22:1303-15; PMID:11850458
    • (2002) J Neurosci , vol.22 , pp. 1303-1315
    • Bonilla, I.E.1    Tanabe, K.2    Strittmatter, S.M.3
  • 40
    • 59649128574 scopus 로고    scopus 로고
    • Expression of the regenerationassociated protein SPRR1A in primary sensory neurons and spinal cord of the adult mouse following peripheral and central injury
    • PMID: 19107756
    • Starkey ML, Davies M, Yip PK, Carter LM, Wong DJ, McMahon SB, et al. Expression of the regenerationassociated protein SPRR1A in primary sensory neurons and spinal cord of the adult mouse following peripheral and central injury. J Comp Neurol 2009; 513:51-68; PMID:19107756; http://dx.doi.org/10.1002/ cne.21944
    • (2009) J Comp Neurol , vol.513 , pp. 51-68
    • Starkey, M.L.1    Davies, M.2    Yip, P.K.3    Carter, L.M.4    Wong, D.J.5    McMahon, S.B.6
  • 41
    • 84873402658 scopus 로고    scopus 로고
    • Klf4 regulates the expression of Slurp1, which functions as an immunomodulatory peptide in the mouse cornea
    • PMID: 23139280
    • Swamynathan S, Buela KA, Kinchington P, Lathrop KL, Misawa H, Hendricks RL, et al. Klf4 regulates the expression of Slurp1, which functions as an immunomodulatory peptide in the mouse cornea. Invest Ophthalmol Vis Sci 2012; 53:8433-46; PMID:23139280; http://dx.doi.org/10.1167/iovs.12-10759
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 8433-8446
    • Swamynathan, S.1    Buela, K.A.2    Kinchington, P.3    Lathrop, K.L.4    Misawa, H.5    Hendricks, R.L.6
  • 42
    • 0344443178 scopus 로고    scopus 로고
    • Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda
    • PMID: 14506129
    • Chimienti F, Hogg RC, Plantard L, Lehmann C, Brakch N, Fischer J, et al. Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda. Hum Mol Genet 2003; 12:3017-24; PMID:14506129; http://dx.doi. org/10.1093/hmg/ddg320
    • (2003) Hum Mol Genet , vol.12 , pp. 3017-3024
    • Chimienti, F.1    Hogg, R.C.2    Plantard, L.3    Lehmann, C.4    Brakch, N.5    Fischer, J.6
  • 43
    • 0036191639 scopus 로고    scopus 로고
    • Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases
    • PMID: 11844744
    • Bianco AC, Salvatore D, Gereben B, Berry MJ, Larsen PR. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev 2002; 23:38-89; PMID:11844744; http://dx.doi.org/10.1210/er.23.1.38
    • (2002) Endocr Rev , vol.23 , pp. 38-89
    • Bianco, A.C.1    Salvatore, D.2    Gereben, B.3    Berry, M.J.4    Larsen, P.R.5
  • 44
    • 0038005018 scopus 로고    scopus 로고
    • DAVID: Database for annotation, visualization, and integrated discovery
    • PMID: 12734009
    • Dennis G Jr., Sherman BT, Hosack DA, Yang J, Gao W, Lane HC, et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol 2003; 4:3; PMID:12734009; http://dx.doi.org/10.1186/gb-2003-4-5-p3
    • (2003) Genome Biol , vol.4 , pp. 3
    • Dennis Jr., G.1    Sherman, B.T.2    Hosack, D.A.3    Yang, J.4    Gao, W.5    Lane, H.C.6
  • 45
    • 79961111552 scopus 로고    scopus 로고
    • Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: The seed and soil also needs fertilizer
    • PMID: 21734470
    • Lisanti MP, Martinez-Outschoorn UE, Lin Z, Pavlides S, Whitaker-Menezes D, Pestell RG, et al. Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs fertilizer. Cell Cycle 2011; 10:2440-9; PMID:21734470; http://dx.doi.org/10.4161/cc.10.15.16870
    • (2011) Cell Cycle , vol.10 , pp. 2440-2449
    • Lisanti, M.P.1    Martinez-Outschoorn, U.E.2    Lin, Z.3    Pavlides, S.4    Whitaker-Menezes, D.5    Pestell, R.G.6
  • 46
    • 84863329778 scopus 로고    scopus 로고
    • Inflammaging: Disturbed interplay between autophagy and inflammasomes
    • Kaarniranta K, Kauppinen A. Inflammaging: disturbed interplay between autophagy and inflammasomes. Salminen A. Aging (Albany, NY Online) 2012; 4:166-75
    • (2012) Salminen A. Aging (Albany, NY Online) , vol.4 , pp. 166-175
    • Kaarniranta, K.1    Kauppinen, A.2
  • 47
    • 84863431784 scopus 로고    scopus 로고
    • Inflammatory cause of metabolic syndrome via brain stress and NF-?B
    • Cai D, Liu T. Inflammatory cause of metabolic syndrome via brain stress and NF-?B. Aging (Albany, NY Online) 2012; 4:98-115
    • (2012) Aging (Albany, NY Online) , vol.4 , pp. 98-115
    • Cai, D.1    Liu, T.2
  • 48
    • 48649088785 scopus 로고    scopus 로고
    • The aged retinal pigment epithelium/choroid: A potential substratum for the pathogenesis of age-related macular degeneration
    • PMID: 18523633
    • Chen H, Liu B, Lukas TJ, Neufeld AH. The aged retinal pigment epithelium/choroid: a potential substratum for the pathogenesis of age-related macular degeneration. PLoS ONE 2008; 3:e2339; PMID:18523633; http://dx.doi.org/10.1371/journal.pone.0002339
    • (2008) PLoS ONE , vol.3
    • Chen, H.1    Liu, B.2    Lukas, T.J.3    Neufeld, A.H.4
  • 49
    • 79953155543 scopus 로고    scopus 로고
    • Immune activation in retinal aging: A gene expression study
    • PMID: 20538981
    • Chen M, Muckersie E, Forrester JV, Xu H. Immune activation in retinal aging: a gene expression study. Invest Ophthalmol Vis Sci 2010; 51:5888-96; PMID:20538981; http://dx.doi.org/10.1167/iovs.09-5103
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 5888-5896
    • Chen, M.1    Muckersie, E.2    Forrester, J.V.3    Xu, H.4
  • 50
    • 67651155742 scopus 로고    scopus 로고
    • Para-inflammation in the aging retina
    • PMID: 19560552
    • Xu H, Chen M, Forrester JV. Para-inflammation in the aging retina. Prog Retin Eye Res 2009; 28:348-68; PMID:19560552; http://dx.doi.org/10.1016/j. preteyeres. 2009.06.001
    • (2009) Prog Retin Eye Res , vol.28 , pp. 348-368
    • Xu, H.1    Chen, M.2    Forrester, J.V.3
  • 51
    • 84872530990 scopus 로고    scopus 로고
    • Gene expression changes in response to aging compared to heat stress, oxidative stress and ionizing radiation in Drosophila melanogaster
    • PMID: 23211361
    • Landis G, Shen J, Tower J. Gene expression changes in response to aging compared to heat stress, oxidative stress and ionizing radiation in Drosophila melanogaster. Aging (Albany NY) 2012; 4:768-89; PMID:23211361
    • (2012) Aging (Albany NY) , vol.4 , pp. 768-789
    • Landis, G.1    Shen, J.2    Tower, J.3
  • 52
    • 84862624052 scopus 로고    scopus 로고
    • Effects of aging and anatomic location on gene expression in human retina
    • PMID: 22666212
    • Cai H, Fields MA, Hoshino R, Priore LV. Effects of aging and anatomic location on gene expression in human retina. Front Aging Neurosci 2012; 4:8; PMID:22666212; http://dx.doi.org/10.3389/fnagi.2012.00008
    • (2012) Front Aging Neurosci , vol.4 , pp. 8
    • Cai, H.1    Fields, M.A.2    Hoshino, R.3    Priore, L.V.4
  • 53
    • 84865130689 scopus 로고    scopus 로고
    • NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens
    • PMID: 22763455
    • Anand PK, Malireddi RKS, Lukens JR, Vogel P, Bertin J, Lamkanfi M, et al. NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. Nature 2012; 488:389-93; PMID:22763455; http://dx.doi.org/10.1038/ nature11250
    • (2012) Nature , vol.488 , pp. 389-393
    • Anand, P.K.1    Rks, M.2    Lukens, J.R.3    Vogel, P.4    Bertin, J.5    Lamkanfi, M.6
  • 54
    • 42449105692 scopus 로고    scopus 로고
    • Immunopathological aspects of agerelated macular degeneration
    • PMID: 18299834
    • Patel M, Chan CC. Immunopathological aspects of agerelated macular degeneration. Semin Immunopathol 2008; 30:97-110; PMID:18299834; http://dx.doi. org/10.1007/s00281-008-0112-9
    • (2008) Semin Immunopathol , vol.30 , pp. 97-110
    • Patel, M.1    Chan, C.C.2
  • 55
    • 84875137211 scopus 로고    scopus 로고
    • Bowman lecture on the role of inflammation in degenerative disease of the eye
    • PMID: 23288138
    • Forrester JV. Bowman lecture on the role of inflammation in degenerative disease of the eye. Eye (Lond) 2013; 27:340-52; PMID:23288138; http://dx.doi. org/10.1038/eye.2012.265
    • (2013) Eye (Lond) , vol.27 , pp. 340-352
    • Forrester, J.V.1
  • 56
    • 21044453724 scopus 로고    scopus 로고
    • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
    • PMID: 15870199
    • Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, Hardisty LI, et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci USA 2005; 102:7227-32; PMID:15870199; http://dx.doi.org/10.1073/pnas.0501536102
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 7227-7232
    • Hageman, G.S.1    Anderson, D.H.2    Johnson, L.V.3    Hancox, L.S.4    Taiber, A.J.5    Hardisty, L.I.6
  • 57
    • 84856918255 scopus 로고    scopus 로고
    • Genetics of immunological and inflammatory components in age-related macular degeneration
    • PMID: 22324898
    • Tuo J, Grob S, Zhang K, Chan CC. Genetics of immunological and inflammatory components in age-related macular degeneration. Ocul Immunol Inflamm 2012; 20:27-36; PMID:22324898; http://dx.doi.org/10.3109/09273948.2011. 628432
    • (2012) Ocul Immunol Inflamm , vol.20 , pp. 27-36
    • Tuo, J.1    Grob, S.2    Zhang, K.3    Chan, C.C.4
  • 58
    • 20544471911 scopus 로고    scopus 로고
    • Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration
    • PMID: 15895326
    • Zareparsi S, Branham KEH, Li M, Shah S, Klein RJ, Ott J, et al. Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration. Am J Hum Genet 2005; 77:149-53; PMID:15895326; http://dx.doi. org/10.1086/431426
    • (2005) Am J Hum Genet , vol.77 , pp. 149-153
    • Zareparsi, S.1    Keh, B.2    Li, M.3    Shah, S.4    Klein, R.J.5    Ott, J.6
  • 59
    • 0034612175 scopus 로고    scopus 로고
    • Inflammation and Alzheimer's disease
    • PMID: 10858586
    • Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, et al. Inflammation and Alzheimer's disease. Neurobiol Aging 2000; 21:383-421; PMID:10858586; http://dx.doi.org/10.1016/S0197-4580(00)00124-X
    • (2000) Neurobiol Aging , vol.21 , pp. 383-421
    • Akiyama, H.1    Barger, S.2    Barnum, S.3    Bradt, B.4    Bauer, J.5    Cole, G.M.6
  • 60
    • 0034012166 scopus 로고    scopus 로고
    • Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
    • PMID: 10783137
    • Mullins RF, Russell SR, Anderson DH, Hageman GS. Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease. FASEB J 2000; 14:835-46; PMID:10783137
    • (2000) FASEB J , vol.14 , pp. 835-846
    • Mullins, R.F.1    Russell, S.R.2    Anderson, D.H.3    Hageman, G.S.4
  • 61
    • 0345760069 scopus 로고    scopus 로고
    • Characterization of beta amyloid assemblies in drusen: The deposits associated with aging and age-related macular degeneration
    • PMID: 14729357
    • Anderson DH, Talaga KC, Rivest AJ, Barron E, Hageman GS, Johnson LV. Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration. Exp Eye Res 2004; 78:243-56; PMID:14729357; http://dx.doi.org/10.1016/j.exer.2003.10.011
    • (2004) Exp Eye Res , vol.78 , pp. 243-256
    • Anderson, D.H.1    Talaga, K.C.2    Rivest, A.J.3    Barron, E.4    Hageman, G.S.5    Johnson, L.V.6
  • 62
    • 84862833670 scopus 로고    scopus 로고
    • Inhibition of Polo-like kinase 1 reduces beta-amyloidinduced neuronal cell death in Alzheimer's disease
    • PMID: 21931181
    • Song B, Davis K, Liu XS, Lee HG, Smith M, Liu X. Inhibition of Polo-like kinase 1 reduces beta-amyloidinduced neuronal cell death in Alzheimer's disease. Aging (Albany NY) 2011; 3:846-51; PMID:21931181
    • (2011) Aging (Albany NY) , vol.3 , pp. 846-851
    • Song, B.1    Davis, K.2    Liu, X.S.3    Lee, H.G.4    Smith, M.5    Liu, X.6
  • 63
    • 84862833303 scopus 로고    scopus 로고
    • Phosphorylation of amyloid beta (A?) peptides -A trigger for formation of toxic aggregates in Alzheimer's disease
    • PMID: 21869458
    • Kumar S, Walter J. Phosphorylation of amyloid beta (A?) peptides -a trigger for formation of toxic aggregates in Alzheimer's disease. Aging (Albany NY) 2011; 3:803-12; PMID:21869458
    • (2011) Aging (Albany NY) , vol.3 , pp. 803-812
    • Kumar, S.1    Walter, J.2
  • 64
    • 0034832029 scopus 로고    scopus 로고
    • An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
    • PMID: 11587915
    • Hageman GS, Luthert PJ, Victor Chong NH, Johnson LV, Anderson DH, Mullins RF. An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res 2001; 20:705-32; PMID:11587915; http://dx.doi.org/10.1016/S1350-9462(01)00010-6
    • (2001) Prog Retin Eye Res , vol.20 , pp. 705-732
    • Hageman, G.S.1    Luthert, P.J.2    Victor Chong, N.H.3    Johnson, L.V.4    Anderson, D.H.5    Mullins, R.F.6
  • 65
    • 84867148658 scopus 로고    scopus 로고
    • New approaches and potential treatments for dry age-related macular degeneration
    • PMID: 22552424
    • Damico FM, Gasparin F, Scolari MR, Pedral LS, Takahashi BS. New approaches and potential treatments for dry age-related macular degeneration. Arq Bras Oftalmol 2012; 75:71-6; PMID:22552424
    • (2012) Arq Bras Oftalmol , vol.75 , pp. 71-76
    • Damico, F.M.1    Gasparin, F.2    Scolari, M.R.3    Pedral, L.S.4    Takahashi, B.S.5
  • 66
    • 77951254301 scopus 로고    scopus 로고
    • Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD)
    • PMID: 20206286
    • Ramkumar HL, Zhang J, Chan CC. Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD). Prog Retin Eye Res 2010; 29:169-90; PMID:20206286; http://dx.doi.org/10.1016/j.preteyeres. 2010.02.002
    • (2010) Prog Retin Eye Res , vol.29 , pp. 169-190
    • Ramkumar, H.L.1    Zhang, J.2    Chan, C.C.3
  • 67
    • 0344676389 scopus 로고    scopus 로고
    • An animal model of age-related macular degeneration in senescent Ccl-2-or Ccr-2-deficient mice
    • PMID: 14566334
    • Ambati J, Anand A, Fernandez S, Sakurai E, Lynn BC, Kuziel WA, et al. An animal model of age-related macular degeneration in senescent Ccl-2-or Ccr-2-deficient mice. Nat Med 2003; 9:1390-7; PMID:14566334; http://dx.doi.org/10.1038/nm950
    • (2003) Nat Med , vol.9 , pp. 1390-1397
    • Ambati, J.1    Anand, A.2    Fernandez, S.3    Sakurai, E.4    Lynn, B.C.5    Kuziel, W.A.6
  • 68
    • 59849104241 scopus 로고    scopus 로고
    • Molecular pathology of age-related macular degeneration
    • PMID: 19026761
    • Ding X, Patel M, Chan CC. Molecular pathology of age-related macular degeneration. Prog Retin Eye Res 2009; 28:1-18; PMID:19026761; http://dx.doi. org/10.1016/j.preteyeres.2008.10.001
    • (2009) Prog Retin Eye Res , vol.28 , pp. 1-18
    • Ding, X.1    Patel, M.2    Chan, C.C.3
  • 69
    • 16544387300 scopus 로고    scopus 로고
    • Activity of cell immune response and open field behavior in Wistar and OXYS rats
    • PMID: 14714088
    • Markova EV, Obukhova LA, Kolosova NG. Activity of cell immune response and open field behavior in Wistar and OXYS rats. Bull Exp Biol Med 2003; 136:377-9; PMID:14714088; http://dx.doi.org/10.1023/B:BEBM.0000010957.87077.ae
    • (2003) Bull Exp Biol Med , vol.136 , pp. 377-379
    • Markova, E.V.1    Obukhova, L.A.2    Kolosova, N.G.3
  • 70
    • 74849133990 scopus 로고    scopus 로고
    • Mitochondria-targeted antioxidant SkQ1 inhibits age-dependent involution of the thymus in normal and senescence-prone rats
    • PMID: 20195490
    • Obukhova LA, Skulachev VP, Kolosova NG. Mitochondria-targeted antioxidant SkQ1 inhibits age-dependent involution of the thymus in normal and senescence-prone rats. Aging (Albany NY) 2009; 1:389-401; PMID:20195490
    • (2009) Aging (Albany NY) , vol.1 , pp. 389-401
    • Obukhova, L.A.1    Skulachev, V.P.2    Kolosova, N.G.3
  • 71
    • 77954681312 scopus 로고    scopus 로고
    • The role of the thymus in immunosenescence: Lessons from the study of thymectomized individuals
    • PMID: 20354268
    • Appay V, Sauce D, Prelog M. The role of the thymus in immunosenescence: lessons from the study of thymectomized individuals. Aging (Albany NY) 2010; 2:78-81; PMID:20354268
    • (2010) Aging (Albany NY) , vol.2 , pp. 78-81
    • Appay, V.1    Sauce, D.2    Prelog, M.3
  • 72
    • 80052390891 scopus 로고    scopus 로고
    • Altered thymic activity in early life: How does it affect the immune system in young adults?
    • PMID: 21752618
    • Sauce D, Appay V. Altered thymic activity in early life: how does it affect the immune system in young adults? Curr Opin Immunol 2011; 23:543-8; PMID:21752618; http://dx.doi.org/10.1016/j. coi.2011.05.001
    • (2011) Curr Opin Immunol , vol.23 , pp. 543-548
    • Sauce, D.1    Appay, V.2
  • 73
    • 77249147331 scopus 로고    scopus 로고
    • The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
    • PMID: 19961953
    • Anderson DH, Radeke MJ, Gallo NB, Chapin EA, Johnson PT, Curletti CR, et al. The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Prog Retin Eye Res 2010; 29:95-112; PMID:19961953; http://dx.doi. org/10.1016/j.preteyeres.2009.11.003
    • (2010) Prog Retin Eye Res , vol.29 , pp. 95-112
    • Anderson, D.H.1    Radeke, M.J.2    Gallo, N.B.3    Chapin, E.A.4    Johnson, P.T.5    Curletti, C.R.6
  • 74
    • 84867916817 scopus 로고    scopus 로고
    • Major histocompatibility complex class i proteins in brain development and plasticity
    • PMID: 22939644
    • Elmer BM, McAllister AK. Major histocompatibility complex class I proteins in brain development and plasticity. Trends Neurosci 2012; 35:660-70; PMID:22939644; http://dx.doi.org/10.1016/j. tins.2012.08.001
    • (2012) Trends Neurosci , vol.35 , pp. 660-670
    • Elmer, B.M.1    McAllister, A.K.2
  • 75
    • 36849076770 scopus 로고    scopus 로고
    • The classical complement cascade mediates CNS synapse elimination
    • PMID: 18083105
    • Stevens B, Allen NJ, Vazquez LE, Howell GR, Christopherson KS, Nouri N, et al. The classical complement cascade mediates CNS synapse elimination. Cell 2007; 131:1164-78; PMID:18083105; http://dx.doi.org/10.1016/j.cell.2007.10.036
    • (2007) Cell , vol.131 , pp. 1164-1178
    • Stevens, B.1    Allen, N.J.2    Vazquez, L.E.3    Howell, G.R.4    Christopherson, K.S.5    Nouri, N.6
  • 76
    • 84872187295 scopus 로고    scopus 로고
    • A novel role of complement in retinal degeneration
    • PMID: 23074214
    • Yu M, Zou W, Peachey NS, McIntyre TM, Liu J. A novel role of complement in retinal degeneration. Invest Ophthalmol Vis Sci 2012; 53:7684-92; PMID:23074214; http://dx.doi.org/10.1167/iovs.12-10069
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 7684-7692
    • Yu, M.1    Zou, W.2    Peachey, N.S.3    McIntyre, T.M.4    Liu, J.5
  • 77
    • 0142056039 scopus 로고    scopus 로고
    • A comprehensive analysis of the expression of crystallins in mouse retina
    • PMID: 12949468
    • Xi J, Farjo R, Yoshida S, Kern TS, Swaroop A, Andley UP. A comprehensive analysis of the expression of crystallins in mouse retina. Mol Vis 2003; 9:410-9; PMID:12949468
    • (2003) Mol Vis , vol.9 , pp. 410-419
    • Xi, J.1    Farjo, R.2    Yoshida, S.3    Kern, T.S.4    Swaroop, A.5    Andley, U.P.6
  • 78
    • 34047272312 scopus 로고    scopus 로고
    • Transfer of lens-specific transcripts to retinal RNA samples may underlie observed changes in crystallin-gene transcript levels after ischemia
    • PMID: 17327827
    • Kamphuis W, Dijk F, Kraan W, Bergen AAB. Transfer of lens-specific transcripts to retinal RNA samples may underlie observed changes in crystallin-gene transcript levels after ischemia. Mol Vis 2007; 13:220-8; PMID:17327827
    • (2007) Mol Vis , vol.13 , pp. 220-228
    • Kamphuis, W.1    Dijk, F.2    Kraan, W.3    Aab, B.4
  • 79
    • 57249086036 scopus 로고    scopus 로고
    • Changes in physicochemical parameters and alpha-crystallin expression in the lens during cataract development in OXYS rats
    • Rumyantseva YV, Fursova AZh, Fedoseeva LA, Kolosova NG. Changes in physicochemical parameters and alpha-crystallin expression in the lens during cataract development in OXYS rats.
    • (2008) 5 Biochemistry (Mosc) , vol.73 , pp. 1176-1182
    • Rumyantseva, Y.V.1    Azh, F.2    Fedoseeva, L.A.3    Kolosova, N.G.4
  • 80
    • 0035844174 scopus 로고    scopus 로고
    • The small heat shock protein alpha B-crystallin negatively regulates cytochrome c-and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation
    • PMID: 11274139
    • Kamradt MC, Chen F, Cryns VL. The small heat shock protein alpha B-crystallin negatively regulates cytochrome c-and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation. J Biol Chem 2001; 276:16059-63; PMID:11274139; http://dx.doi.org/10.1074/jbc.C100107200
    • (2001) J Biol Chem , vol.276 , pp. 16059-16063
    • Kamradt, M.C.1    Chen, F.2    Cryns, V.L.3
  • 81
    • 77951491586 scopus 로고    scopus 로고
    • AlphaB-crystallin: A novel VEGF chaperone
    • PMID: 20413662
    • Kerr BA, Byzova TV. alphaB-crystallin: a novel VEGF chaperone. Blood 2010; 115:3181-3; PMID:20413662; http://dx.doi.org/10.1182/blood-2010-01-262766
    • (2010) Blood , vol.115 , pp. 3181-3183
    • Kerr, B.A.1    Byzova, T.V.2
  • 82
    • 34147145520 scopus 로고    scopus 로고
    • Alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress
    • PMID: 17438522
    • Yaung J, Jin M, Barron E, Spee C, Wawrousek EF, Kannan R, et al. alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress. Mol Vis 2007; 13:566-77; PMID:17438522
    • (2007) Mol Vis , vol.13 , pp. 566-577
    • Yaung, J.1    Jin, M.2    Barron, E.3    Spee, C.4    Wawrousek, E.F.5    Kannan, R.6
  • 83
    • 39149145829 scopus 로고    scopus 로고
    • Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia
    • PMID: 18191123
    • Yaung J, Kannan R, Wawrousek EF, Spee C, Sreekumar PG, Hinton DR. Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia. Exp Eye Res 2008; 86:355-65; PMID:18191123; http://dx.doi. org/10.1016/j.exer.2007.11.007
    • (2008) Exp Eye Res , vol.86 , pp. 355-365
    • Yaung, J.1    Kannan, R.2    Wawrousek, E.F.3    Spee, C.4    Sreekumar, P.G.5    Hinton, D.R.6
  • 84
    • 77951448229 scopus 로고    scopus 로고
    • AlphaB-crystallin regulation of angiogenesis by modulation of VEGF
    • PMID: 20023214
    • Kase S, He S, Sonoda S, Kitamura M, Spee C, Wawrousek E, et al. alphaB-crystallin regulation of angiogenesis by modulation of VEGF. Blood 2010; 115:3398-406; PMID:20023214; http://dx.doi. org/10.1182/blood-2009-01-197095
    • (2010) Blood , vol.115 , pp. 3398-3406
    • Kase, S.1    He, S.2    Sonoda, S.3    Kitamura, M.4    Spee, C.5    Wawrousek, E.6
  • 85
    • 78049354924 scopus 로고    scopus 로고
    • Thiol redox transitions by thioredoxin and thioredoxin-binding protein-2 in cell signaling
    • PMID: 20609905
    • Yoshihara E, Chen Z, Matsuo Y, Masutani H, Yodoi J. Thiol redox transitions by thioredoxin and thioredoxin-binding protein-2 in cell signaling. Methods Enzymol 2010; 474:67-82; PMID:20609905; http://dx.doi.org/10.1016/S0076- 6879(10)74005-2
    • (2010) Methods Enzymol , vol.474 , pp. 67-82
    • Yoshihara, E.1    Chen, Z.2    Matsuo, Y.3    Masutani, H.4    Yodoi, J.5
  • 86
    • 33745300235 scopus 로고    scopus 로고
    • Age-associated changes in oxidative damage and the activity of antioxidant enzymes in rats with inherited overgeneration of free radicals
    • PMID: 16563232
    • Sinitsyna O, Krysanova Z, Ishchenko A, Dikalova AE, Stolyarov S, Kolosova N, et al. Age-associated changes in oxidative damage and the activity of antioxidant enzymes in rats with inherited overgeneration of free radicals. J Cell Mol Med 2006; 10:206-15; PMID:16563232; http://dx.doi. org/10.1111/j.1582- 4934.2006.tb00301.x
    • (2006) J Cell Mol Med , vol.10 , pp. 206-215
    • Sinitsyna, O.1    Krysanova, Z.2    Ishchenko, A.3    Dikalova, A.E.4    Stolyarov, S.5    Kolosova, N.6
  • 87
    • 33745998064 scopus 로고    scopus 로고
    • Long-term antioxidant supplementation attenuates oxidative stress markers and cognitive deficits in senescent-accelerated OXYS rats
    • PMID: 16246464
    • Kolosova NG, Shcheglova TV, Sergeeva SV, Loskutova LV. Long-term antioxidant supplementation attenuates oxidative stress markers and cognitive deficits in senescent-accelerated OXYS rats. Neurobiol Aging 2006; 27:1289-97; PMID:16246464; http://dx.doi. org/10.1016/j.neurobiolaging.2005.07.022
    • (2006) Neurobiol Aging , vol.27 , pp. 1289-1297
    • Kolosova, N.G.1    Shcheglova, T.V.2    Sergeeva, S.V.3    Loskutova, L.V.4
  • 88
    • 84863726788 scopus 로고    scopus 로고
    • Consequences of oxidative stress in age-related macular degeneration
    • PMID: 22510306
    • Jarrett SG, Boulton ME. Consequences of oxidative stress in age-related macular degeneration. Mol Aspects Med 2012; 33:399-417; PMID:22510306; http://dx.doi.org/10.1016/j.mam.2012.03.009
    • (2012) Mol Aspects Med , vol.33 , pp. 399-417
    • Jarrett, S.G.1    Boulton, M.E.2
  • 89
    • 84878597422 scopus 로고    scopus 로고
    • Association between polymorphism of the NQO1, NOS3 and NFE2L2 genes and AMD
    • PMID: 23276910
    • Synowiec E, Sliwinski T, Danisz K, Blasiak J, Sklodowska A, Romaniuk D, et al. Association between polymorphism of the NQO1, NOS3 and NFE2L2 genes and AMD. Front Biosci 2013; 18:80-90; PMID:23276910; http://dx.doi.org/10.2741/4088
    • (2013) Front Biosci , vol.18 , pp. 80-90
    • Synowiec, E.1    Sliwinski, T.2    Danisz, K.3    Blasiak, J.4    Sklodowska, A.5    Romaniuk, D.6
  • 90
    • 84862603833 scopus 로고    scopus 로고
    • DNA methylation is associated with altered gene expression in AMD
    • PMID: 22410570
    • Hunter A, Spechler PA, Cwanger A, Song Y, Zhang Z, Ying GS, et al. DNA methylation is associated with altered gene expression in AMD. Invest Ophthalmol Vis Sci 2012; 53:2089-105; PMID:22410570; http://dx.doi.org/10.1167/iovs.11- 8449
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 2089-2105
    • Hunter, A.1    Spechler, P.A.2    Cwanger, A.3    Song, Y.4    Zhang, Z.5    Ying, G.S.6
  • 91
    • 34347335719 scopus 로고    scopus 로고
    • Downregulation of glutaredoxin but not glutathione loss leads to mitochondrial dysfunction in female mice CNS: Implications in excitotoxicity
    • PMID: 17512091
    • Diwakar L, Kenchappa RS, Annepu J, Ravindranath V. Downregulation of glutaredoxin but not glutathione loss leads to mitochondrial dysfunction in female mice CNS: implications in excitotoxicity. Neurochem Int 2007; 51:37-46; PMID:17512091; http://dx.doi. org/10.1016/j.neuint.2007.03.008
    • (2007) Neurochem Int , vol.51 , pp. 37-46
    • Diwakar, L.1    Kenchappa, R.S.2    Annepu, J.3    Ravindranath, V.4
  • 92
    • 0037390718 scopus 로고    scopus 로고
    • Glutaredoxin is essential for maintenance of brain mitochondrial complex I: Studies with MPTP
    • PMID: 12594173
    • Kenchappa RS, Ravindranath V. Glutaredoxin is essential for maintenance of brain mitochondrial complex I: studies with MPTP. FASEB J 2003; 17:717-9; PMID:12594173
    • (2003) FASEB J , vol.17 , pp. 717-719
    • Kenchappa, R.S.1    Ravindranath, V.2
  • 93
    • 33746406453 scopus 로고    scopus 로고
    • Mitochondrial alterations of retinal pigment epithelium in age-related macular degeneration
    • PMID: 15979212
    • Feher J, Kovacs I, Artico M, Cavallotti C, Papale A, Balacco Gabrieli C. Mitochondrial alterations of retinal pigment epithelium in age-related macular degeneration. Neurobiol Aging 2006; 27:983-93; PMID:15979212; http://dx.doi.org/10.1016/j.neurobiolaging. 2005.05.012
    • (2006) Neurobiol Aging , vol.27 , pp. 983-993
    • Feher, J.1    Kovacs, I.2    Artico, M.3    Cavallotti, C.4    Papale, A.5    Balacco Gabrieli, C.6
  • 94
    • 0028076277 scopus 로고
    • Impairment of respiratory functions in mitochondria of rats with an inherited hyperproduction of free radicals
    • PMID: 7999021
    • Salganik RI, Shabalina IG, Solovyova NA, Kolosova NG, Solovyov VN, Kolpakov AR. Impairment of respiratory functions in mitochondria of rats with an inherited hyperproduction of free radicals. Biochem Biophys Res Commun 1994; 205:180-5; PMID:7999021; http://dx.doi.org/10.1006/bbrc.1994.2647
    • (1994) Biochem Biophys Res Commun , vol.205 , pp. 180-185
    • Salganik, R.I.1    Shabalina, I.G.2    Solovyova, N.A.3    Kolosova, N.G.4    Solovyov, V.N.5    Kolpakov, A.R.6
  • 95
    • 0035712726 scopus 로고    scopus 로고
    • Dynamics of structural and functional changes in hepatocyte mitochondria of senescence-accelerated OXYS rats
    • PMID: 11713575
    • Kolosova NG, Aidagulova SV, Nepomnyashchikh GI, Shabalina IG, Shalbueva NI. Dynamics of structural and functional changes in hepatocyte mitochondria of senescence-accelerated OXYS rats. Bull Exp Biol Med 2001; 132:814-9; PMID:11713575; http://dx.doi. org/10.1023/A:1013014919721
    • (2001) Bull Exp Biol Med , vol.132 , pp. 814-819
    • Kolosova, N.G.1    Aidagulova, S.V.2    Nepomnyashchikh, G.I.3    Shabalina, I.G.4    Shalbueva, N.I.5
  • 96
    • 0034612075 scopus 로고    scopus 로고
    • A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients
    • PMID: 10858595
    • Maurer I, Zierz S, Möller HJ. A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients. Neurobiol Aging 2000; 21:455-62; PMID:10858595; http://dx.doi.org/10.1016/S0197-4580(00)00112-3
    • (2000) Neurobiol Aging , vol.21 , pp. 455-462
    • Maurer, I.1    Zierz, S.2    Möller, H.J.3
  • 97
    • 0036875316 scopus 로고    scopus 로고
    • The role of apoptosis in age-related macular degeneration
    • PMID: 12427055
    • Dunaief JL, Dentchev T, Ying GS, Milam AH. The role of apoptosis in age-related macular degeneration. Arch Ophthalmol 2002; 120:1435-42; PMID:12427055
    • (2002) Arch Ophthalmol , vol.120 , pp. 1435-1442
    • Dunaief, J.L.1    Dentchev, T.2    Ying, G.S.3    Milam, A.H.4
  • 98
    • 84868136294 scopus 로고    scopus 로고
    • Enhanced apoptosis in retinal pigment epithelium under inflammatory stimuli and oxidative stress
    • PMID: 22911474
    • Wang Y, Shen D, Wang VM, Yu CR, Wang RX, Tuo J, et al. Enhanced apoptosis in retinal pigment epithelium under inflammatory stimuli and oxidative stress. Apoptosis 2012; 17:1144-55; PMID:22911474; http://dx.doi.org/10.1007/s10495-012- 0750-1
    • (2012) Apoptosis , vol.17 , pp. 1144-1155
    • Wang, Y.1    Shen, D.2    Wang, V.M.3    Yu, C.R.4    Wang, R.X.5    Tuo, J.6
  • 99
    • 33845333359 scopus 로고    scopus 로고
    • The extracellular release of HMGB1 during apoptotic cell death
    • PMID:16855214
    • Bell CW, Jiang W, Reich CF 3rd, Pisetsky DS. The extracellular release of HMGB1 during apoptotic cell death. Am J Physiol Cell Physiol 2006; 291:C1318-25; PMID:16855214; http://dx.doi.org/10.1152/ajpcell. 00616.2005
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Bell, C.W.1    Jiang, W.2    Reich, C.F.3    Pisetsky, D.S.4
  • 100
    • 84871495233 scopus 로고    scopus 로고
    • C-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis
    • PMID:23250397
    • Piao X, Komazawa-Sakon S, Nishina T, Koike M, Piao JH, Ehlken H, et al. c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis. Sci Signal 2012; 5:ra93; PMID:23250397; http://dx.doi.org/10.1126/ scisignal.2003558
    • (2012) Sci Signal , vol.5
    • Piao, X.1    Komazawa-Sakon, S.2    Nishina, T.3    Koike, M.4    Piao, J.H.5    Ehlken, H.6
  • 101
    • 33645401537 scopus 로고    scopus 로고
    • Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration
    • PMID:16505012
    • Nordgaard CL, Berg KM, Kapphahn RJ, Reilly C, Feng X, Olsen TW, et al. Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration. Invest Ophthalmol Vis Sci 2006; 47:815-22; PMID:16505012; http://dx.doi.org/10.1167/iovs.05-0976
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 815-822
    • Nordgaard, C.L.1    Berg, K.M.2    Kapphahn, R.J.3    Reilly, C.4    Feng, X.5    Olsen, T.W.6
  • 102
    • 34547124106 scopus 로고    scopus 로고
    • An RNAi-based genetic screen for oxidative stress resistance reveals retinol saturase as a mediator of stress resistance
    • PMID:17664141
    • Nagaoka-Yasuda R, Matsuo N, Perkins B, Limbaeck-Stokin K, Mayford M. An RNAi-based genetic screen for oxidative stress resistance reveals retinol saturase as a mediator of stress resistance. Free Radic Biol Med 2007; 43:781-8; PMID:17664141; http://dx.doi. org/10.1016/j.freeradbiomed.2007.05.008
    • (2007) Free Radic Biol Med , vol.43 , pp. 781-788
    • Nagaoka-Yasuda, R.1    Matsuo, N.2    Perkins, B.3    Limbaeck-Stokin, K.4    Mayford, M.5
  • 103
    • 0034256090 scopus 로고    scopus 로고
    • Calmodulin: A prototypical calcium sensor
    • PMID:10884684
    • Chin D, Means AR. Calmodulin: a prototypical calcium sensor. Trends Cell Biol 2000; 10:322-8; PMID:10884684; http://dx.doi.org/10.1016/S0962-8924(00) 01800-6
    • (2000) Trends Cell Biol , vol.10 , pp. 322-328
    • Chin, D.1    Means, A.R.2
  • 104
    • 33344459382 scopus 로고    scopus 로고
    • Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: Indication of distinct receptor involvement
    • PMID:16278303
    • Hayhoe RPG, Kamal AM, Solito E, Flower RJ, Cooper D, Perretti M. Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement. Blood 2006; 107:2123-30; PMID:16278303; http://dx.doi.org/10.1182/blood-2005-08-3099
    • (2006) Blood , vol.107 , pp. 2123-2130
    • Rpg, H.1    Kamal, A.M.2    Solito, E.3    Flower, R.J.4    Cooper, D.5    Perretti, M.6
  • 105
    • 1942486365 scopus 로고    scopus 로고
    • Annexin 1: More than an antiphospholipase protein
    • PMID:15060718
    • Parente L, Solito E. Annexin 1: more than an antiphospholipase protein. Inflamm Res 2004; 53:125-32; PMID:15060718; http://dx.doi.org/10.1007/s00011- 003-1235-z
    • (2004) Inflamm Res , vol.53 , pp. 125-132
    • Parente, L.1    Solito, E.2
  • 106
    • 0142229704 scopus 로고    scopus 로고
    • Intracellular and extracellular roles of S100 proteins
    • PMID:12645002
    • Donato R. Intracellular and extracellular roles of S100 proteins. Microsc Res Tech 2003; 60:540-51; PMID:12645002; http://dx.doi.org/10.1002/jemt.10296
    • (2003) Microsc Res Tech , vol.60 , pp. 540-551
    • Donato, R.1
  • 107
    • 84870533099 scopus 로고    scopus 로고
    • The S100A6 calcium-binding protein regulates endothelial cell-cycle progression and senescence
    • PMID:23095053
    • Bao L, Odell AF, Stephen SL, Wheatcroft SB, Walker JH, Ponnambalam S. The S100A6 calcium-binding protein regulates endothelial cell-cycle progression and senescence. FEBS J 2012; 279:4576-88; PMID:23095053; http://dx.doi.org/10.1111/ febs.12044
    • (2012) FEBS J , vol.279 , pp. 4576-4588
    • Bao, L.1    Odell, A.F.2    Stephen, S.L.3    Wheatcroft, S.B.4    Walker, J.H.5    Ponnambalam, S.6
  • 108
    • 79960990341 scopus 로고    scopus 로고
    • Serine proteases, serine protease inhibitors, and protease-activated receptors: Roles in synaptic function and behavior
    • PMID:21782155
    • Almonte AG, Sweatt JD. Serine proteases, serine protease inhibitors, and protease-activated receptors: roles in synaptic function and behavior. Brain Res 2011; 1407:107-22; PMID:21782155; http://dx.doi. org/10.1016/j.brainres.2011. 06.042
    • (2011) Brain Res , vol.1407 , pp. 107-122
    • Almonte, A.G.1    Sweatt, J.D.2
  • 109
    • 0141925717 scopus 로고    scopus 로고
    • Extracellular proteases and their inhibitors in genetic diseases of the central nervous system
    • PMID:12925575
    • Molinari F, Meskanaite V, Munnich A, Sonderegger P, Colleaux L. Extracellular proteases and their inhibitors in genetic diseases of the central nervous system. Hum Mol Genet 2003; 12(Spec No):R195-200; PMID:12925575; http://dx.doi.org/10.1093/hmg/ddg276
    • (2003) Hum Mol Genet , vol.12
    • Molinari, F.1    Meskanaite, V.2    Munnich, A.3    Sonderegger, P.4    Colleaux, L.5
  • 111
    • 4444223559 scopus 로고    scopus 로고
    • Under stress, the absence of intermediate filaments from Müller cells in the retina has structural and functional consequences
    • PMID:15226376
    • Lundkvist A, Reichenbach A, Betsholtz C, Carmeliet P, Wolburg H, Pekny M. Under stress, the absence of intermediate filaments from Müller cells in the retina has structural and functional consequences. J Cell Sci 2004; 117:3481-8; PMID:15226376; http://dx.doi. org/10.1242/jcs.01221
    • (2004) J Cell Sci , vol.117 , pp. 3481-3488
    • Lundkvist, A.1    Reichenbach, A.2    Betsholtz, C.3    Carmeliet, P.4    Wolburg, H.5    Pekny, M.6
  • 112
    • 77953162265 scopus 로고    scopus 로고
    • Quantitative proteomics: Comparison of the macular Bruch membrane/choroid complex from agerelated macular degeneration and normal eyes
    • PMID:20177130
    • Yuan X, Gu X, Crabb JS, Yue X, Shadrach K, Hollyfield JG, et al. Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from agerelated macular degeneration and normal eyes. Mol Cell Proteomics 2010; 9:1031-46; PMID:20177130; http://dx.doi.org/10.1074/mcp. M900523-MCP200
    • (2010) Mol Cell Proteomics , vol.9 , pp. 1031-1046
    • Yuan, X.1    Gu, X.2    Crabb, J.S.3    Yue, X.4    Shadrach, K.5    Hollyfield, J.G.6
  • 113
    • 80054857902 scopus 로고    scopus 로고
    • Brain proteoglycans in postnatal development and during behavior decline in senescence-accelerated OXYS rats
    • PMID:21957580
    • Rykova VI, Leberfarb EY, Stefanova NA, Shevelev OB, Dymshits GM, Kolosova NG. Brain proteoglycans in postnatal development and during behavior decline in senescence-accelerated OXYS rats. Adv Gerontol 2011; 24:234-43; PMID:21957580
    • (2011) Adv Gerontol , vol.24 , pp. 234-243
    • Rykova, V.I.1    Leberfarb, E.Y.2    Stefanova, N.A.3    Shevelev, O.B.4    Dymshits, G.M.5    Kolosova, N.G.6
  • 114
    • 84896557728 scopus 로고    scopus 로고
    • OXYS rats: A prospective model for evaluation of antioxidant availability in prevention and therapy of accelerated aging and age-related cognitive decline
    • In: Gariépy Q, Ménard R, eds. Nova Science Publishers, NY
    • Kolosova NG, Stefanova NA, Sergeeva SV. OXYS rats: a prospective model for evaluation of antioxidant availability in prevention and therapy of accelerated aging and age-related cognitive decline. In: Gariépy Q, Ménard R, eds. Handbook of Cognitive Aging: Causes, Processes and Effects. Nova Science Publishers, NY: 47-82.
    • Handbook of Cognitive Aging: Causes, Processes and Effects , pp. 47-82
    • Kolosova, N.G.1    Stefanova, N.A.2    Sergeeva, S.V.3
  • 115
    • 79951561948 scopus 로고    scopus 로고
    • The role of antiinflammatory agents in age-related macular degeneration (AMD) treatment
    • PMID:21183941
    • Wang Y, Wang VM, Chan CC. The role of antiinflammatory agents in age-related macular degeneration (AMD) treatment. Eye (Lond) 2011; 25:127-39; PMID:21183941; http://dx.doi.org/10.1038/eye.2010.196
    • (2011) Eye (Lond) , vol.25 , pp. 127-139
    • Wang, Y.1    Wang, V.M.2    Chan, C.C.3
  • 116
    • 84871180605 scopus 로고    scopus 로고
    • Age-related macular degeneration revisited-piecing the puzzle: The LXIX Edward Jackson memorial lecture
    • PMID:23245386
    • Miller JW. Age-related macular degeneration revisited-piecing the puzzle: the LXIX Edward Jackson memorial lecture. Am J Ophthalmol 2013; 155:1, e13; PMID:23245386; http://dx.doi.org/10.1016/j. ajo.2012.10.018
    • (2013) Am J Ophthalmol , vol.155
    • Miller, J.W.1
  • 117
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • PMID:19289445
    • Trapnell C, Pachter L, Salzberg SL. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 2009; 25:1105-11; PMID:19289445; http://dx.doi. org/10.1093/bioinformatics/btp120
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.