Transcriptional regulation of rod photoreceptor homeostasis revealed by in vivo NRL targetome analysis

PLoS Genetics

Volumn 8, Issue 4, 2012, Pages

  Hao, Hong ^a,f   Kim, Douglas S ^a   Klocke, Bernward ^b   Johnson, Kory R ^c   Cui, Kairong ^d   Gotoh, Norimoto ^a   Zang, Chongzhi ^e,g   Gregorski, Janina ^a   Gieser, Linn ^a   Peng, Weiqun ^e   Fann, Yang ^c   Seifert, Martin ^b   Zhao, Keji ^d   Swaroop, Anand ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b Genomatix GmbH   (Germany)

^c NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^d NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^e GEORGE WASHINGTON UNIVERSITY   (United States)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^g HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEMETHYLASE; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CRX; TRANSCRIPTION FACTOR NRL; UNCLASSIFIED DRUG; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CONE ROD HOMEOBOX PROTEIN; DNA BINDING PROTEIN; EYE PROTEIN; HOMEODOMAIN PROTEIN; KDM5B PROTEIN, MOUSE; NRL PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; DOWN REGULATION; GENE; GENE EXPRESSION PROFILING; GENE MAPPING; GENE OVEREXPRESSION; GENE REGULATORY NETWORK; GENE SILENCING; GENETIC ASSOCIATION; HIGH THROUGHPUT SEQUENCING; HOMEOSTASIS; IN VIVO STUDY; KDM5B GENE; MOUSE; NONHUMAN; NRL GENE; PATHOPHYSIOLOGY; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; RETINA CONE; RETINA DYSTROPHY; RETINA ROD; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; VISUAL SYSTEM FUNCTION; WISP1 GENE; ANIMAL; C57BL MOUSE; DISEASE MODEL; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; NERVE CELL; PHYSIOLOGY; RETINA;

MAMMALIA;

ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BINDING SITES; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; EYE PROTEINS; GENE KNOCKDOWN TECHNIQUES; GENE REGULATORY NETWORKS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HOMEODOMAIN PROTEINS; HOMEOSTASIS; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; MICE; MICE, INBRED C57BL; NEURONS; RETINA; RETINAL DYSTROPHIES; RETINAL ROD PHOTORECEPTOR CELLS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84860572048     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002649     Document Type: Article

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