-
1
-
-
0034800655
-
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no 8
-
Anon A. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no 8. Arch. Ophthalmol. 119:2001;1417-1436.
-
(2001)
Arch. Ophthalmol.
, vol.119
, pp. 1417-1436
-
-
Anon, A.1
-
3
-
-
0034766552
-
Mitochondrial abnormalities in ageing macular photoreceptors
-
Barron M.J., Johnson M.A., Andrews R.M., Clarke M.P., Griffiths P.G., Bristow E., He L.P., Durham S., Turnbull D.M. Mitochondrial abnormalities in ageing macular photoreceptors. Invest. Ophthalmol. Vis. Sci. 42:2001;3016-3022.
-
(2001)
Invest. Ophthalmol. Vis. Sci.
, vol.42
, pp. 3016-3022
-
-
Barron, M.J.1
Johnson, M.A.2
Andrews, R.M.3
Clarke, M.P.4
Griffiths, P.G.5
Bristow, E.6
He, L.P.7
Durham, S.8
Turnbull, D.M.9
-
4
-
-
0035142770
-
Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population
-
Beatty S., Murray I.J., Henson D.B., Carden D., Koh H., Boulton M.E. Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population. Invest. Ophthalmol. Vis. Sci. 42:2001;439-446.
-
(2001)
Invest. Ophthalmol. Vis. Sci.
, vol.42
, pp. 439-446
-
-
Beatty, S.1
Murray, I.J.2
Henson, D.B.3
Carden, D.4
Koh, H.5
Boulton, M.E.6
-
5
-
-
0026496708
-
Standardized full-field electroretinography, Normal values and their variation with age
-
Birch D.G., Anderson J.L. Standardized full-field electroretinography, Normal values and their variation with age. Arch. Ophthalmol. 110:1992;1571-1576.
-
(1992)
Arch. Ophthalmol.
, vol.110
, pp. 1571-1576
-
-
Birch, D.G.1
Anderson, J.L.2
-
6
-
-
0028934221
-
An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group
-
Bird A.C., Bressler N.M., Bressler S.B., Chisholm I.H., Coscas G., Davis M.D., de Jong P.T., Klaver C.C., Klein B.E., Klein R., et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv. Ophthalmol. 39:1995;367-374.
-
(1995)
Surv. Ophthalmol.
, vol.39
, pp. 367-374
-
-
Bird, A.C.1
Bressler, N.M.2
Bressler, S.B.3
Chisholm, I.H.4
Coscas, G.5
Davis, M.D.6
De Jong, P.T.7
Klaver, C.C.8
Klein, B.E.9
Klein, R.10
-
7
-
-
0027325869
-
Lipofuscin is a photoinducible free radical generator
-
Boulton M., Dontsov A., Jarvis-Evans J., Ostrovsky M., Svistunenko D. Lipofuscin is a photoinducible free radical generator. J. Photochem. Photobiol. B. 19:1993;201-204.
-
(1993)
J. Photochem. Photobiol. B
, vol.19
, pp. 201-204
-
-
Boulton, M.1
Dontsov, A.2
Jarvis-Evans, J.3
Ostrovsky, M.4
Svistunenko, D.5
-
8
-
-
0032499711
-
Disease sequence from mutant rhodopsin allele to rod and cone photoreceptor degeneration in man
-
Cideciyan A.V., Hood D.C., Huang Y., Banin E., Li Z.Y., Stone E.M., Milam A.H., Jacobson S.G. Disease sequence from mutant rhodopsin allele to rod and cone photoreceptor degeneration in man. Proc. Natl. Acad. Sci. USA. 95:1998;7103-7108.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7103-7108
-
-
Cideciyan, A.V.1
Hood, D.C.2
Huang, Y.3
Banin, E.4
Li, Z.Y.5
Stone, E.M.6
Milam, A.H.7
Jacobson, S.G.8
-
9
-
-
0034644203
-
A one-hit model of cell death in inherited neuronal degenerations
-
Clarke G., Collins R.A., Leavitt B.R., Andrews D.F., Hayden M.R., Lumsden C.J., McInnes R.R. A one-hit model of cell death in inherited neuronal degenerations. Nature. 406:2000;195-199.
-
(2000)
Nature
, vol.406
, pp. 195-199
-
-
Clarke, G.1
Collins, R.A.2
Leavitt, B.R.3
Andrews, D.F.4
Hayden, M.R.5
Lumsden, C.J.6
McInnes, R.R.7
-
10
-
-
0027401626
-
Retinal ganglion cells in Alzheimer's disease and aging
-
Curcio C.A., Drucker D.N. Retinal ganglion cells in Alzheimer's disease and aging. Ann. Neurol. 33:1993;248-257.
-
(1993)
Ann. Neurol.
, vol.33
, pp. 248-257
-
-
Curcio, C.A.1
Drucker, D.N.2
-
12
-
-
0027368450
-
Aging of the human photoreceptor mosaic: Evidence for selective vulnerability of rods in central retina
-
Curcio C.A., Millican C.L., Allen K.A., Kalina R.E. Aging of the human photoreceptor mosaic: evidence for selective vulnerability of rods in central retina. Invest. Ophthalmol. Vis. Sci. 34:1993;3278-3296.
-
(1993)
Invest. Ophthalmol. Vis. Sci.
, vol.34
, pp. 3278-3296
-
-
Curcio, C.A.1
Millican, C.L.2
Allen, K.A.3
Kalina, R.E.4
-
13
-
-
0033924382
-
Spare the rods, save the cones in aging and age-related maculopathy
-
Curcio C.A., Owsley C., Jackson G.R. Spare the rods, save the cones in aging and age-related maculopathy. Invest. Ophthalmol. Vis. Sci. 41:2000;2015-2018.
-
(2000)
Invest. Ophthalmol. Vis. Sci.
, vol.41
, pp. 2015-2018
-
-
Curcio, C.A.1
Owsley, C.2
Jackson, G.R.3
-
15
-
-
0027410970
-
Retinal age pigments generated by self-assembling lysosomotropic detergents
-
Eldred G.E., Lasky M.R. Retinal age pigments generated by self-assembling lysosomotropic detergents. Nature. 361:1993;724-726.
-
(1993)
Nature
, vol.361
, pp. 724-726
-
-
Eldred, G.E.1
Lasky, M.R.2
-
16
-
-
0021752680
-
Age-related macular degeneration and blindness due to neovascular maculopathy
-
Ferris F.L. III, Fine S.L., Hyman L. Age-related macular degeneration and blindness due to neovascular maculopathy. Arch. Ophthalmol. 102:1984;1640-1642.
-
(1984)
Arch. Ophthalmol.
, vol.102
, pp. 1640-1642
-
-
Ferris F.L. III1
Fine, S.L.2
Hyman, L.3
-
17
-
-
0037308591
-
Partial characterization of retina-derived cone neuroprotection in two culture models of photoreceptor degeneration
-
Fintz A.C., Audo I., Hicks D., Mohand-Said S., Leveillard T., Sahel J. Partial characterization of retina-derived cone neuroprotection in two culture models of photoreceptor degeneration. Invest. Ophthalmol. Vis. Sci. 44:2003;818-825.
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 818-825
-
-
Fintz, A.C.1
Audo, I.2
Hicks, D.3
Mohand-Said, S.4
Leveillard, T.5
Sahel, J.6
-
18
-
-
0036362470
-
Decline of photopic multifocal electroretinogram responses with age is due primarily to preretinal optical factors
-
Fortune B., Johnson C.A. Decline of photopic multifocal electroretinogram responses with age is due primarily to preretinal optical factors. J. Opt. Soc. Am. A Opt. Image Sci. Vis. 19:2002;173-184.
-
(2002)
J. Opt. Soc. Am. A Opt. Image Sci. Vis.
, vol.19
, pp. 173-184
-
-
Fortune, B.1
Johnson, C.A.2
-
19
-
-
0026502611
-
Aging of the human retina. Differential loss of neurons and retinal pigment epithelial cells
-
Gao H., Hollyfield J.G. Aging of the human retina. Differential loss of neurons and retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 33:1992;1-17.
-
(1992)
Invest. Ophthalmol. Vis. Sci.
, vol.33
, pp. 1-17
-
-
Gao, H.1
Hollyfield, J.G.2
-
20
-
-
0036956564
-
Multifocal electroretinogram: Age-related changes for different luminance levels
-
Gerth C., Garcia S.M., Ma L., Keltner J.L., Werner J.S. Multifocal electroretinogram: age-related changes for different luminance levels. Graefes Arch. Clin. Exp. Ophthalmol. 240:2002;202-208.
-
(2002)
Graefes Arch. Clin. Exp. Ophthalmol.
, vol.240
, pp. 202-208
-
-
Gerth, C.1
Garcia, S.M.2
Ma, L.3
Keltner, J.L.4
Werner, J.S.5
-
21
-
-
0001160866
-
Average optical performance of the human eye as a function of age in a normal population
-
Guirao A., Gonzalez C., Redondo M., Geraghty E., Norrby S., Artal P. Average optical performance of the human eye as a function of age in a normal population. Invest. Ophthalmol. Vis. Sci. 40:1999;203-213.
-
(1999)
Invest. Ophthalmol. Vis. Sci.
, vol.40
, pp. 203-213
-
-
Guirao, A.1
Gonzalez, C.2
Redondo, M.3
Geraghty, E.4
Norrby, S.5
Artal, P.6
-
24
-
-
0032697707
-
The implications of rod-dependent cone survival for basic and clinical research
-
Hicks D., Sahel J. The implications of rod-dependent cone survival for basic and clinical research. Invest. Ophthalmol. Vis. Sci. 40:1999;3071-3074.
-
(1999)
Invest. Ophthalmol. Vis. Sci.
, vol.40
, pp. 3071-3074
-
-
Hicks, D.1
Sahel, J.2
-
25
-
-
0033926670
-
Scotopic sensitivity during adulthood
-
Jackson G.R., Owsley C. Scotopic sensitivity during adulthood. Vis. Res. 40:2000;2467-2473.
-
(2000)
Vis. Res.
, vol.40
, pp. 2467-2473
-
-
Jackson, G.R.1
Owsley, C.2
-
26
-
-
0036356404
-
Aging-related changes in the multifocal electroretinogram
-
Jackson G.R., Ortega J., Girkin C., Rosenstiel C.E., Owsley C. Aging-related changes in the multifocal electroretinogram. J. Opt. Soc. Am. A Opt. Image Sci. Vis. 19:2002;185-189.
-
(2002)
J. Opt. Soc. Am. A Opt. Image Sci. Vis.
, vol.19
, pp. 185-189
-
-
Jackson, G.R.1
Ortega, J.2
Girkin, C.3
Rosenstiel, C.E.4
Owsley, C.5
-
27
-
-
0035042776
-
A literature network of human genes for high-throughput analysis of gene expression
-
Jenssen T.K., Laegreid A., Komorowski J., Hovig E. A literature network of human genes for high-throughput analysis of gene expression. Nat. Genet. 28:2001;21-28.
-
(2001)
Nat. Genet.
, vol.28
, pp. 21-28
-
-
Jenssen, T.K.1
Laegreid, A.2
Komorowski, J.3
Hovig, E.4
-
28
-
-
0037015020
-
The Alzheimer's A beta-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration
-
Johnson L.V., Leitner W.P., Rivest A.J., Staples M.K., Radeke M.J., Anderson D.H. The Alzheimer's A beta-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration. Proc. Natl. Acad. Sci. USA. 99:2002;11830-11835.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11830-11835
-
-
Johnson, L.V.1
Leitner, W.P.2
Rivest, A.J.3
Staples, M.K.4
Radeke, M.J.5
Anderson, D.H.6
-
29
-
-
0026681119
-
Prevalence of age-related maculopathy. The Beaver Dam eye study
-
Klein R., Klein B.E., Linton K.L. Prevalence of age-related maculopathy. The Beaver Dam eye study. Ophthalmology. 99:1992;933-943.
-
(1992)
Ophthalmology
, vol.99
, pp. 933-943
-
-
Klein, R.1
Klein, B.E.2
Linton, K.L.3
-
31
-
-
0031766152
-
Ocular neovascularization: An epidemiologic review
-
Lee P., Wang C.C., Adamis A.P. Ocular neovascularization: an epidemiologic review. Surv. Ophthalmol. 43:1998;245-269.
-
(1998)
Surv. Ophthalmol.
, vol.43
, pp. 245-269
-
-
Lee, P.1
Wang, C.C.2
Adamis, A.P.3
-
32
-
-
0036402152
-
Proteasome function and protein oxidation in the aged retina
-
Louie J., Kapphahn R., Ferrington D. Proteasome function and protein oxidation in the aged retina. Exp. Eye Res. 75:2002;271.
-
(2002)
Exp. Eye Res.
, vol.75
, pp. 271
-
-
Louie, J.1
Kapphahn, R.2
Ferrington, D.3
-
33
-
-
0035097420
-
Preservation of ganglion cell layer neurons in age-related macular degeneration
-
Medeiros N.E., Curcio C.A. Preservation of ganglion cell layer neurons in age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 42:2001;795-803.
-
(2001)
Invest. Ophthalmol. Vis. Sci.
, vol.42
, pp. 795-803
-
-
Medeiros, N.E.1
Curcio, C.A.2
-
34
-
-
0032493433
-
Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse
-
Mohand-Said S., Deudon-Combe A., Hicks D., Simonutti M., Forster V., Fintz A.C., Leveillard T., Dreyfus H., Sahel J.A. Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse. Proc. Natl. Acad. Sci. USA. 95:1998;8357-8362.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8357-8362
-
-
Mohand-Said, S.1
Deudon-Combe, A.2
Hicks, D.3
Simonutti, M.4
Forster, V.5
Fintz, A.C.6
Leveillard, T.7
Dreyfus, H.8
Sahel, J.A.9
-
35
-
-
0034081449
-
Selective transplantation of rods delays cone loss in a retinitis pigmentosa model
-
Mohand-Said S., Hicks D., Dreyfus H., Sahel J.A. Selective transplantation of rods delays cone loss in a retinitis pigmentosa model. Arch. Ophthalmol. 118:2000;807-811.
-
(2000)
Arch. Ophthalmol.
, vol.118
, pp. 807-811
-
-
Mohand-Said, S.1
Hicks, D.2
Dreyfus, H.3
Sahel, J.A.4
-
36
-
-
0034993535
-
Rod-cone interactions: Developmental and clinical significance
-
Mohand-Said S., Hicks D., Leveillard T., Picaud S., Porto F., Sahel J.A. Rod-cone interactions: developmental and clinical significance. Prog. Retin. Eye Res. 20:2001;451-467.
-
(2001)
Prog. Retin. Eye Res.
, vol.20
, pp. 451-467
-
-
Mohand-Said, S.1
Hicks, D.2
Leveillard, T.3
Picaud, S.4
Porto, F.5
Sahel, J.A.6
-
37
-
-
0034012166
-
Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
-
Mullins R.F., Russell S.R., Anderson D.H., Hageman G.S. Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease. Faseb J. 14:2000;835-846.
-
(2000)
Faseb J.
, vol.14
, pp. 835-846
-
-
Mullins, R.F.1
Russell, S.R.2
Anderson, D.H.3
Hageman, G.S.4
-
38
-
-
0033989336
-
Psychophysical evidence for rod vulnerability in age-related macular degeneration
-
Owsley C., Jackson G.R., Cideciyan A.V., Huang Y., Fine S.L., Ho A.C., Maguire M.G., Lolley V., Jacobson S.G. Psychophysical evidence for rod vulnerability in age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 41:2000;267-273.
-
(2000)
Invest. Ophthalmol. Vis. Sci.
, vol.41
, pp. 267-273
-
-
Owsley, C.1
Jackson, G.R.2
Cideciyan, A.V.3
Huang, Y.4
Fine, S.L.5
Ho, A.C.6
Maguire, M.G.7
Lolley, V.8
Jacobson, S.G.9
-
39
-
-
0034972178
-
Delays in rod-mediated dark adaptation in early age-related maculopathy
-
Owsley C., Jackson G.R., White M., Feist R., Edwards D. Delays in rod-mediated dark adaptation in early age-related maculopathy. Ophthalmology. 108:2001;1196-1202.
-
(2001)
Ophthalmology
, vol.108
, pp. 1196-1202
-
-
Owsley, C.1
Jackson, G.R.2
White, M.3
Feist, R.4
Edwards, D.5
-
40
-
-
0030851707
-
Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa
-
Petters R.M., Alexander C.A., Wells K.D., Collins E.B., Sommer J.R., Blanton M.R., Rojas G., Hao Y., Flowers W.L., Banin E., Cideciyan A.V., Jacobson S.G., Wong F. Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa. Nat. Biotechnol. 15:1997;965-970.
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 965-970
-
-
Petters, R.M.1
Alexander, C.A.2
Wells, K.D.3
Collins, E.B.4
Sommer, J.R.5
Blanton, M.R.6
Rojas, G.7
Hao, Y.8
Flowers, W.L.9
Banin, E.10
Cideciyan, A.V.11
Jacobson, S.G.12
Wong, F.13
-
41
-
-
0035662961
-
Changes of astrocytes in retinal ageing and age-related macular degeneration
-
Ramirez J.M., Ramirez A.I., Salazar J.J., de Hoz R., Trivino A. Changes of astrocytes in retinal ageing and age-related macular degeneration. Exp. Eye Res. 73:2001;601-615.
-
(2001)
Exp. Eye Res.
, vol.73
, pp. 601-615
-
-
Ramirez, J.M.1
Ramirez, A.I.2
Salazar, J.J.3
De Hoz, R.4
Trivino, A.5
-
42
-
-
0032871253
-
Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration: Results of retreatments in a phase 1 and 2 study
-
Schmidt-Erfurth U., Miller J.W., Sickenberg M., Laqua H., Barbazetto I., Gragoudas E.S., Zografos L., Piguet B., Pournaras C.J., Donati G., Lane A.M., Birngruber R., van den Berg H., Strong H.A., Manjuris U., Gray T., Fsadni M., Bressler N.M. Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration: results of retreatments in a phase 1 and 2 study. Arch. Ophthalmol. 117:1999;1177-1187.
-
(1999)
Arch. Ophthalmol.
, vol.117
, pp. 1177-1187
-
-
Schmidt-Erfurth, U.1
Miller, J.W.2
Sickenberg, M.3
Laqua, H.4
Barbazetto, I.5
Gragoudas, E.S.6
Zografos, L.7
Piguet, B.8
Pournaras, C.J.9
Donati, G.10
Lane, A.M.11
Birngruber, R.12
Van Den Berg, H.13
Strong, H.A.14
Manjuris, U.15
Gray, T.16
Fsadni, M.17
Bressler, N.M.18
-
43
-
-
0000117096
-
Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin
-
Schutt F., Davies S., Kopitz J., Holz F.G., Boulton M.E. Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin. Invest. Ophthalmol. Vis. Sci. 41:2000;2303-2308.
-
(2000)
Invest. Ophthalmol. Vis. Sci.
, vol.41
, pp. 2303-2308
-
-
Schutt, F.1
Davies, S.2
Kopitz, J.3
Holz, F.G.4
Boulton, M.E.5
-
44
-
-
0034086115
-
The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells
-
Sparrow J.R., Nakanishi K., Parish C.A. The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells. Invest. Ophthalmol. Vis. Sci. 41:2000;1981-1989.
-
(2000)
Invest. Ophthalmol. Vis. Sci.
, vol.41
, pp. 1981-1989
-
-
Sparrow, J.R.1
Nakanishi, K.2
Parish, C.A.3
-
45
-
-
0035475141
-
Molecular genetics of age-related macular degeneration
-
Stone E.M., Sheffield V.C., Hageman G.S. Molecular genetics of age-related macular degeneration. Hum. Mol. Genet. 10:2001;2285-2292.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 2285-2292
-
-
Stone, E.M.1
Sheffield, V.C.2
Hageman, G.S.3
-
46
-
-
0034671726
-
Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells
-
Suter M., Reme C., Grimm C., Wenzel A., Jaattela M., Esser P., Kociok N., Leist M., Richter C. Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells. J. Biol. Chem. 275:2000;39625-39630.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39625-39630
-
-
Suter, M.1
Reme, C.2
Grimm, C.3
Wenzel, A.4
Jaattela, M.5
Esser, P.6
Kociok, N.7
Leist, M.8
Richter, C.9
-
47
-
-
0033588376
-
The photoreactivity of the retinal age pigment lipofuscin
-
Wassell J., Davies S., Bardsley W., Boulton M. The photoreactivity of the retinal age pigment lipofuscin. J. Biol. Chem. 274:1999;23828-23832.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23828-23832
-
-
Wassell, J.1
Davies, S.2
Bardsley, W.3
Boulton, M.4
-
48
-
-
0019413127
-
The effect of age on human cone and rod ganzfeld electroretinograms
-
Weleber R.G. The effect of age on human cone and rod ganzfeld electroretinograms. Invest. Ophthalmol. Vis. Sci. 20:1981;392-399.
-
(1981)
Invest. Ophthalmol. Vis. Sci.
, vol.20
, pp. 392-399
-
-
Weleber, R.G.1
-
51
-
-
0014972425
-
Shedding of discs from rod outer segments in the rhesus monkey
-
Young R.W. Shedding of discs from rod outer segments in the rhesus monkey. J. Ultrastruct. Res. 34:1971;190-203.
-
(1971)
J. Ultrastruct. Res.
, vol.34
, pp. 190-203
-
-
Young, R.W.1
|