The histamine H4 receptor: From orphan to the clinic

Frontiers in Pharmacology

Volumn 6, Issue MAR, 2015, Pages

  Thurmond, Robin L ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Arthritis; Asthma; Atopic dermatitis; Histamine; Pruritus

Indexed keywords

1 (5 CHLORO 2 BENZIMIDAZOLYLCARBONYL) 4 METHYLPIPERAZINE; 1 (5 CHLORO 2 INDOLYLCARBONYL) 4 METHYLPIPERAZINE; BETA ARRESTIN; HISTAMINE H4 RECEPTOR; HISTAMINE H4 RECEPTOR ANTAGONIST; JNJ 39758979; UNCLASSIFIED DRUG;

ANTIPRURITIC ACTIVITY; ASTHMA; ATOPIC DERMATITIS; CELL SHAPE; CHEMOTAXIS; DRUG ACTIVITY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG TARGETING; EC50; EOSINOPHIL; EOSINOPHILIA; HUMAN; IC50; MAST CELL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHASE 2 CLINICAL TRIAL (TOPIC); PROTEIN EXPRESSION; PROTEIN INDUCTION; PRURITUS; REVIEW; T LYMPHOCYTE ACTIVATION;

EID: 84926452299     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2015.00065     Document Type: Review

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