Histamine H4 receptor antagonist ameliorates chronic allergic contact dermatitis induced by repeated challenge

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 65, Issue 3, 2010, Pages 319-326

  Seike, M ^a   Furuya, K ^a   Omura, M ^a   Hamada Watanabe, K ^a   Matsushita, A ^a   Ohtsu, H ^b  

^a SAGAMI WOMEN'S UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Chronic allergic contact dermatitis; Cytokine, histamine; H4 receptor; Mast cell

Indexed keywords

1 (5 CHLORO 2 INDOLYLCARBONYL) 4 METHYLPIPERAZINE; 4 METHYLHISTAMINE; GAMMA INTERFERON; HISTAMINE H4 RECEPTOR; HISTIDINE DECARBOXYLASE; IMMUNOGLOBULIN E; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; EOSINOPHIL; FEMALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; SKIN ALLERGY;

ANIMALS; CHEMOTAXIS, LEUKOCYTE; CHRONIC DISEASE; CYTOKINES; DERMATITIS, ALLERGIC CONTACT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTAMINE AGONISTS; HISTAMINE ANTAGONISTS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; PICRYL CHLORIDE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE;

EID: 76249129682     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2009.02240.x     Document Type: Article

References (34)

1. Oda T, Morikawa N, Saito Y, Maruho Y, Yamamoto S. Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes. J Biol Chem 2000 275 : 36781 36786.
2. Liu C, Wilson SJ, Kuei C, Lovenberg TW. Comparison of human, mouse, rat and guinea pig histamine H4 receptors reveals substantial pharmacological species variation. J Pharmacol Exp Ther 2001 299 : 121 130.
3. Ling P, Ngo K, Nguyen S, Thurmond RL, Edwards JP, Karlsson L et al. Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation. Br J Pharmacol 2004 142 : 161 171.
4. Buckland KF, Williams TJ, Conroy DM. Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor. Br J Pharmacol 2003 140 : 1117 1127.
5. Hofstra CL, Desai PJ, Thurmond RL, Fung-Leung WP. Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells. J Pharmacol Exp Ther 2003 305 : 1212 1221.
6. Thurmond RL, Desai PJ, Dunford PJ, Fung-Leung WP, Hofstra CL, Jiang W et al. A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties. J Pharmacol Exp Ther 2004 309 : 404 413.
7. 4 receptor. J Allergy Clin Immunol 2007 120 : 300 307.
8. Dijkstra D, Stark H, Chazot PL, Shenton FC, Leurs R, Werfel T et al. Human inflammatory dendritic epidermal cells express a functional histamine H(4) receptor. J Invest Dermatol 2008 128 : 1696 1703.
9. Kitagaki H, Fujisawa S, Watanabe K, Hayakawa K, Shiohara T. Immediate-type hypersensitivity response followed by a late reaction is induced by repeated epicutaneous application of contact sensitization agents in mice. J Invest Dermatol 1995 105 : 749 755.
10. Kitagaki H, Ono N, Hayakawa K, Kitazawa T, Watanabe K, Shiohara T. Repeated elicitation of contact hypersensitivity induces a shift in cutaneous cytokine milieu from a T helper cell type 1 to a T helper cell type 2 profile. J Immunol 1997 159 : 2484 2491.
11. Seike M, Takata T, Ikeda M, Kodama H, Terui T, Ohtsu H. Histamine helps development of eczematous lesions in experimental contact dematitis in mice. Arch Dermatol Res 2005 297 : 68 74.
12. Hamada R, Seike M, Kamijima R, Ikeda M, Kodama H, Ohtsu H. Neuronal conditions of spinal cord in dermatitis are improved by olopatadine. Eur J Pharmacol 2006 547 : 45 51.
13. Ohtsu H, Tanaka S, Terui T, Hori Y, Makabe-Kobayashi Y, Pejler G et al. Mice lacking histidine decarboxylase exhibit abnormal mast cells. FEBS Lett 2001 502 : 53 56.
14. Oka S, Wakui J, Ikeda S, Yanagimoto S, Kishimoto S, Gokoh M et al. Involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachidonoylglycerol in oxazolone-induced contact dermatitis in mice. J Immunol 2006 177 : 8796 8805.
15. Gray D. Immunological memory. Annu Rev Immunol 1993 11 : 49 77.
16. Tokura Y, Kobayashi M, Ito T, Takahashi H, Matsubara A, Takigawa M. Anti-allergic drug olopatadine suppresses murine contact hypersensitivity and downmodulates antigen-presenting ability of epidermal Langerhans cells. Cell Immunol 2003 224 : 47 54.
17. Belsito DV, Kerdel FA, Potozkin J, Soter NA. Cimetidine-induced augmentation of allergic contact hypersensitivity reactions in mice. J Invest Dermatol 1990 94 : 441 445.
18. Rossbach K, Wendorff S, Sander K, Stark H, Gutzmer R, Werfel T et al. Histamine H4 receptor antagonism reduces hapten-induced scratching behaviour but not inflammation. Exp Dermatol 2009 18 : 57 63.
19. Ohtsu H, Kuramasu A, Tanaka S, Terui T, Hirasawa N, Hara M et al. Plasma extravasation induced by dietary supplemented histamine in histamine-free mice. Eur J Immunol 2002 32 : 1698 1708.
20. Cooper KD. Atopic dermatitis: recent trends in pathogenesis and therapy. J Invest Dermatol 1994 102 : 128 137.
21. Ohmen JD, Hanifin JM, Nickoloff BJ, Rea TH, Wyzykowski R, Kim J et al. Overexpression of IL-10 in atopic dermatitis. Contrasting cytokine patterns with delayed-type hypersensitivity reactions. J Immunol 1995 154 : 1956 1963.
22. Wang G, Savinko T, Wolff H, Dieu-Nosjean MC, Kemeny L, Homey B et al. Repeated epicutaneous exposures to ovalbumin progressively induce atopic dermatitis-like lesions in mice. Clin Exp Allergy 2007 37 : 151 161.
23. Man MQ, Hatano Y, Lee SH, Man M, Chang S, Feingold KR et al. Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges. J Invest Dermatol 2008 128 : 79 86.
24. Yu S, Stahl E, Li Q, Quyang A. Antigen inhalation induces mast cells and eosinophils in the guinea pig esophageal epithelium involving histamine-mediated pathway. Life Sci 2008 82 : 324 330.
25. Seike M, Ikeda M, Kodama H, Terui T, Ohtsu H. Inhibition of scratching behaviour caused by contact dermatitis in histidine decarboxylase gene knockout mice. Exp Dermatol 2005 14 : 169 175.
26. 4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus. J Allergy Clin Immunol 2007 119 : 176 183.
27. Campos RA, Szczepanik M, Itakura A, Akahira-Azuma M, Sidobre S, Kronenberg M et al. Cutaneous immunization rapidly activates liver invariant Valpha 14 NKT cells stimulating B-1 B cells to initiate T cell recruitment for elicitation of contact sensitivity. J Exp Med 2003 198 : 1785 1796.
28. O'Leary JG, Goodarizi M, Drayton DL, von Andrian UH. T cell- and B cell-independent agaptive immunity medicated by natural killer cells. Nat Immunol 2006 7 : 507 516.
29. Leite-de-Moraes MC, Diem S, Michel ML, Ohtsu H, Thurmond RL, Schneider E et al. Cutting edge: Histamine receptor H4 activation positively regulates in vivo IL-4 and IFN-gamma production by invariant NKT cells. J Immunol 2009 182 : 1233 1236.
30. Novak N, Valenta R, Bohle B, Laffer S, Haberstok J, Kraft S et al. FcepsilonRI engagement of Langerhans cell-like dendritic cells and inflammatory dendritic epidermal cell-like dendritic cells induces chemotactic signals and different T-cell phenotypes in vitro. J Allergy Clin Immunol 2004 113 : 949 957.
31. Dunford PJ, O'Donnell N, Riley JP, Williams KN, Karlsson L, Thurmond RL. The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells. J Immunol 2006 176 : 7062 7070.
32. Kühn R, Rajewsky K, Müller W. Generation and analysis of interleukin-4 deficient mice. Science 1991 254 : 707 710.
33. Kajosaari M, Saarinen UM. Evaluation of laboratory tests in childhood allergy. Total serum IgE, blood eosinophilia and eosinophil and mast cells in nasal mucosa of 178 children aged 3 years. Allergy 1981 36 : 329 335.
34. Hamid Q, Boguniewicz M, Leung DY. Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis. J Clin Invest 1994 94 : 870 876.