메뉴 건너뛰기




Volumn , Issue , 2014, Pages 143-192

Peripheral Neuronal Mechanism of Itch: Histamine and Itch

Author keywords

[No Author keywords available]

Indexed keywords


EID: 85137469932     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/b16573-14     Document Type: Chapter
Times cited : (24)

References (416)
  • 1
    • 0031920720 scopus 로고    scopus 로고
    • Effect of fexofenadine on eosinophil-induced changes in epithelial permeability and cytokine release from nasal epithelial cells of patients with seasonal allergic rhinitis
    • Abdelaziz MM, Devalia JL, Khair OA, Bayram H, Prior AJ and Davies RJ (1998) Effect of fexofenadine on eosinophil-induced changes in epithelial permeability and cytokine release from nasal epithelial cells of patients with seasonal allergic rhinitis. J. Allergy Clin. Immunol. 101: 410-420.
    • (1998) J. Allergy Clin. Immunol. , vol.101 , pp. 410-420
    • Abdelaziz, M.M.1    Devalia, J.L.2    Khair, O.A.3    Bayram, H.4    Prior, A.J.5    Davies, R.J.6
  • 2
    • 0001457770 scopus 로고
    • Presence of histamine (4-imidozoleethylamine) in the hypophy-sis cerebri and other tissues of the body and its occurrence among the hydrolytic decom-position products of proteins
    • Abel JJ and Kubota S (1919) Presence of histamine (4-imidozoleethylamine) in the hypophy-sis cerebri and other tissues of the body and its occurrence among the hydrolytic decom-position products of proteins. J. Pharmacol. 13: 243-300.
    • (1919) J. Pharmacol. , vol.13 , pp. 243-300
    • Abel, J.J.1    Kubota, S.2
  • 3
    • 0031661326 scopus 로고    scopus 로고
    • Evaluation of olopatadine, a new ophthalmic antiallergic agent with dual activity, using the conjunctival allergen challenge model
    • Abelson MB (1998) Evaluation of olopatadine, a new ophthalmic antiallergic agent with dual activity, using the conjunctival allergen challenge model. Ann. Allergy Asthma Immunol. 81: 211-218.
    • (1998) Ann. Allergy Asthma Immunol. , vol.81 , pp. 211-218
    • Abelson, M.B.1
  • 4
    • 0018839591 scopus 로고
    • Effects of topically applied occular decongestant and antihistamine
    • Abelson MB, Allansmith MR and Friedlaender MH (1980) Effects of topically applied occular decongestant and antihistamine. Am. J. Ophthalmol. 90: 254-257.
    • (1980) Am. J. Ophthalmol. , vol.90 , pp. 254-257
    • Abelson, M.B.1    Allansmith, M.R.2    Friedlaender, M.H.3
  • 5
    • 0025166468 scopus 로고
    • Conjunctival allergen challenge. A clinical approach to studying allergic conjunctivitis
    • Abelson MB, Chambers WA and Smith LM (1990) Conjunctival allergen challenge. A clinical approach to studying allergic conjunctivitis. Arch. Ophthalmol. 108: 84-88.
    • (1990) Arch. Ophthalmol. , vol.108 , pp. 84-88
    • Abelson, M.B.1    Chambers, W.A.2    Smith, L.M.3
  • 6
    • 0028876819 scopus 로고
    • Evaluation of 0.05% levocabastine versus 4% sodium cromolyn in the allergen challenge model
    • Abelson MB, George MA and Smith LM (1995) Evaluation of 0.05% levocabastine versus 4% sodium cromolyn in the allergen challenge model. Ophthalmology 102: 310-316.
    • (1995) Ophthalmology , vol.102 , pp. 310-316
    • Abelson, M.B.1    George, M.A.2    Smith, L.M.3
  • 7
    • 0036203667 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled compari-son of emedastine 0.05% ophthalmic solution with loratadine 10 mg and their combina-tion in the human conjunctival allergen challenge model
    • Abelson MB and Kaplan AP (2002) A randomized, double-blind, placebo-controlled compari-son of emedastine 0.05% ophthalmic solution with loratadine 10 mg and their combina-tion in the human conjunctival allergen challenge model. Clin. Ther. 24: 445-456.
    • (2002) Clin. Ther. , vol.24 , pp. 445-456
    • Abelson, M.B.1    Kaplan, A.P.2
  • 8
    • 0032586307 scopus 로고    scopus 로고
    • The added benefit of local Patanol therapy when combined with systemic Claritin for the inhibition of ocular itching in the conjunctival antigen challenge model
    • Abelson MB and Lanier RQ (1999) The added benefit of local Patanol therapy when combined with systemic Claritin for the inhibition of ocular itching in the conjunctival antigen challenge model. Acta Ophthalmol. Scand. Suppl. 228: 53-56.
    • (1999) Acta Ophthalmol. Scand. Suppl. , vol.228 , pp. 53-56
    • Abelson, M.B.1    Lanier, R.Q.2
  • 9
    • 0023689594 scopus 로고
    • Levocabastine. Evaluation in the histamine and compound 48/80 models of ocular allergy in humans
    • Abelson MB and Smith LM (1988) Levocabastine. Evaluation in the histamine and compound 48/80 models of ocular allergy in humans. Ophthalmology 95: 1494-1497.
    • (1988) Ophthalmology , vol.95 , pp. 1494-1497
    • Abelson, M.B.1    Smith, L.M.2
  • 10
    • 72149104776 scopus 로고    scopus 로고
    • Time to onset and duration of action of the antihistamine bepotastine besilate ophthalmic solutions 1.0% and 1.5% in allergic conjunctivitis: A phase III, single-center, prospec-tive, randomized, double-masked, placebo-controlled, conjunctival allergen challenge assessment in adults and children
    • Abelson MB, Torkildsen GL, Williams JI, Gow JA, Gomes PJ and McNamara TR (2009) Time to onset and duration of action of the antihistamine bepotastine besilate ophthalmic solutions 1.0% and 1.5% in allergic conjunctivitis: A phase III, single-center, prospec-tive, randomized, double-masked, placebo-controlled, conjunctival allergen challenge assessment in adults and children. Clin. Ther. 31: 1908-1921.
    • (2009) Clin. Ther. , vol.31 , pp. 1908-1921
    • Abelson, M.B.1    Torkildsen, G.L.2    Williams, J.I.3    Gow, J.A.4    Gomes, P.J.5    McNamara, T.R.6
  • 11
    • 0019391781 scopus 로고
    • H2-receptors in the human ocular surface
    • Abelson MB and Udell IJ (1981) H2-receptors in the human ocular surface. Arch. Ophthalmol. 99: 302-304.
    • (1981) Arch. Ophthalmol. , vol.99 , pp. 302-304
    • Abelson, M.B.1    Udell, I.J.2
  • 12
    • 0033626457 scopus 로고    scopus 로고
    • An evaluation of onset and duration of action of patanol (olopatadine hydrochloride ophthalmic solution 0.1%) compared to Claritin (loratadine 10 mg) tablets in acute allergic conjunctivitis in the conjunctival allergen challenge model
    • Abelson MB and Welch DL (2000) An evaluation of onset and duration of action of patanol (olopatadine hydrochloride ophthalmic solution 0.1%) compared to Claritin (loratadine 10 mg) tablets in acute allergic conjunctivitis in the conjunctival allergen challenge model. Acta Ophthalmol. Scand. Suppl. 230: 60-63.
    • (2000) Acta Ophthalmol. Scand. Suppl. , vol.230 , pp. 60-63
    • Abelson, M.B.1    Welch, D.L.2
  • 13
    • 0033626460 scopus 로고    scopus 로고
    • Comparative study of clinical efficacy and tolerance in seasonal allergic conjunctivitis management with 0.1% olopatadine hydrochloride versus 0.05% ketoti-fen fumarate
    • Aguilar AJ (2000) Comparative study of clinical efficacy and tolerance in seasonal allergic conjunctivitis management with 0.1% olopatadine hydrochloride versus 0.05% ketoti-fen fumarate. Acta Ophthalmol. Scand. Suppl. 230: 52-55.
    • (2000) Acta Ophthalmol. Scand. Suppl. , vol.230 , pp. 52-55
    • Aguilar, A.J.1
  • 15
    • 33745379354 scopus 로고    scopus 로고
    • Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report
    • Akdis CA, Akdis M, Bieber T, Bindslev-Jensen C, Boguniewicz M, Eigenmann P, Hamid Q et al. (2006) Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. J. Allergy Clin. Immunol. 118: 152-169.
    • (2006) J. Allergy Clin. Immunol. , vol.118 , pp. 152-169
    • Akdis, C.A.1    Akdis, M.2    Bieber, T.3    Bindslev-Jensen, C.4    Boguniewicz, M.5    Eigenmann, P.6    Hamid, Q.7
  • 16
    • 34247387613 scopus 로고    scopus 로고
    • Olopatadine hydrochloride accelerates the recovery of skin barrier function in mice
    • Amano T, Takeda T, Yano H and Tamura T (2007) Olopatadine hydrochloride accelerates the recovery of skin barrier function in mice. Br. J. Dermatol. 156: 906-912.
    • (2007) Br. J. Dermatol. , vol.156 , pp. 906-912
    • Amano, T.1    Takeda, T.2    Yano, H.3    Tamura, T.4
  • 17
    • 0035155197 scopus 로고    scopus 로고
    • Spinothalamic lamina I neurons selectively sensitive to hista-mine: A central neural pathway for itch
    • Andrew D and Craig AD (2001) Spinothalamic lamina I neurons selectively sensitive to hista-mine: A central neural pathway for itch. Nat. Neurosci. 4: 72-77.
    • (2001) Nat. Neurosci. , vol.4 , pp. 72-77
    • Andrew, D.1    Craig, A.D.2
  • 18
    • 40849086359 scopus 로고    scopus 로고
    • Clinical benefits of combination treatment with mometasone furoate nasal spray and loratadine vs monotherapy with mometasone furoate in the treatment of sea-sonal allergic rhinitis
    • Anolik R (2008) Clinical benefits of combination treatment with mometasone furoate nasal spray and loratadine vs monotherapy with mometasone furoate in the treatment of sea-sonal allergic rhinitis. Ann. Allergy Asthma Immunol. 100: 264-271.
    • (2008) Ann. Allergy Asthma Immunol. , vol.100 , pp. 264-271
    • Anolik, R.1
  • 19
    • 84857030583 scopus 로고    scopus 로고
    • Interactions of recom-binant human histamine H1, H2, H3, and H4 receptors with 34 antidepressants and antipsychotics
    • Appl H, Holzammer T, Dove S, Haen E, Strasser A and Seifert R (2012) Interactions of recom-binant human histamine H1, H2, H3, and H4 receptors with 34 antidepressants and antipsychotics. Naunyn-Schmiedeberg’s Arch. Pharmacol. 385: 145-170.
    • (2012) Naunyn-Schmiedeberg’s Arch. Pharmacol. , vol.385 , pp. 145-170
    • Appl, H.1    Holzammer, T.2    Dove, S.3    Haen, E.4    Strasser, A.5    Seifert, R.6
  • 20
    • 0020587209 scopus 로고
    • Autoinhibition of brain histamine release mediated by a novel class (H3) of histamine receptor
    • Arrang JM, Garbarg M and Schwartz JC (1983) Autoinhibition of brain histamine release mediated by a novel class (H3) of histamine receptor. Nature 302: 832-837.
    • (1983) Nature , vol.302 , pp. 832-837
    • Arrang, J.M.1    Garbarg, M.2    Schwartz, J.C.3
  • 22
    • 0013936967 scopus 로고
    • Receptors mediating some action of histamine
    • Ash ASF and Schild JO (1966) Receptors mediating some action of histamine. Br. J. Pharmacol. 27: 427-439.
    • (1966) Br. J. Pharmacol. , vol.27 , pp. 427-439
    • Ash, A.S.F.1    Schild, J.O.2
  • 23
    • 78651013895 scopus 로고
    • Effect of antihistamine substances on gastric secretion in man
    • Ashford CA, Heller H and Smart GA (1949) Effect of antihistamine substances on gastric secretion in man. Br. J. Pharmacol. Chemother. 4: 157-161.
    • (1949) Br. J. Pharmacol. Chemother. , vol.4 , pp. 157-161
    • Ashford, C.A.1    Heller, H.2    Smart, G.A.3
  • 24
    • 0024591301 scopus 로고
    • Comparison of rifampicin with pheno-barbitone for treatment of pruritus in biliary cirrhosis
    • Bachs L, Pares A, Elena M, Piera C and Rodes J (1989) Comparison of rifampicin with pheno-barbitone for treatment of pruritus in biliary cirrhosis. Lancet 1: 574-576.
    • (1989) Lancet , vol.1 , pp. 574-576
    • Bachs, L.1    Pares, A.2    Elena, M.3    Piera, C.4    Rodes, J.5
  • 25
    • 37049051153 scopus 로고
    • Evaluation of drugs in man, with special reference to antihistamines
    • Bain WA (1951) Evaluation of drugs in man, with special reference to antihistamines. Analyst 76: 573-579.
    • (1951) Analyst , vol.76 , pp. 573-579
    • Bain, W.A.1
  • 26
    • 50349126513 scopus 로고
    • Comparison of anthisan (mepyramine maleate) and phenergan as histamine antagonists
    • Bain WA, Broadbent JL and Warin RP (1949) Comparison of anthisan (mepyramine maleate) and phenergan as histamine antagonists. Lancet 257: 47-52.
    • (1949) Lancet , vol.257 , pp. 47-52
    • Bain, W.A.1    Broadbent, J.L.2    Warin, R.P.3
  • 27
    • 0034752736 scopus 로고    scopus 로고
    • Histamine H1-receptor activation of nuclear factor-kB: Roles for Gbg- and Gaq/11-subunits in constitutive and agonist-mediated signaling
    • Bakker RA, Schoonus SBJ, Smit MJ, Timmerman H and Leurs R (2001) Histamine H1-receptor activation of nuclear factor-kB: Roles for Gbg- and Gaq/11-subunits in constitutive and agonist-mediated signaling. Mol. Pharmacol. 60: 1133-1142.
    • (2001) Mol. Pharmacol. , vol.60 , pp. 1133-1142
    • Bakker, R.A.1    Schoonus, S.B.J.2    Smit, M.J.3    Timmerman, H.4    Leurs, R.5
  • 28
    • 0344774236 scopus 로고
    • 4-β-Aminoethylglyoxaline (β-Aminazolylethylamine) and the other active principles of ergot
    • Barger G and Dale HH (1910) 4-β-Aminoethylglyoxaline (β-Aminazolylethylamine) and the other active principles of ergot. J. Chem. Soc., Trans. 97: 2592-2595.
    • (1910) J. Chem. Soc., Trans. , vol.97 , pp. 2592-2595
    • Barger, G.1    Dale, H.H.2
  • 29
    • 85137475784 scopus 로고
    • 4-β-Aminoethylglyoxaline (β-aminazolylethylamine) and the other active principles of wrgot
    • Barger G and Dale HH (1911) 4-β-Aminoethylglyoxaline (β-aminazolylethylamine) and the other active principles of wrgot. Proc. Chem. Soc., London. 26:327.
    • (1911) Proc. Chem. Soc., London , vol.26 , pp. 327
    • Barger, G.1    Dale, H.H.2
  • 30
    • 51349097261 scopus 로고    scopus 로고
    • Histamine H4 receptors modulate dendritic cell migration through skin-immu-nomodulatory role of histamine
    • Bäumer W, Wendorff S, Gutzmer R, Werfel T, Dijkstra D, Chazot P, Stark H and Kietzmann M (2008) Histamine H4 receptors modulate dendritic cell migration through skin-immu-nomodulatory role of histamine. Allergy 63: 1387-1394.
    • (2008) Allergy , vol.63 , pp. 1387-1394
    • Bäumer, W.1    Wendorff, S.2    Gutzmer, R.3    Werfel, T.4    Dijkstra, D.5    Chazot, P.6    Stark, H.7    Kietzmann, M.8
  • 31
    • 2942530381 scopus 로고    scopus 로고
    • Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in BalbC mice
    • Bell JK, McQueen DS and Rees JL (2004) Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in BalbC mice. Br. J. Pharmacol. 142: 374-380.
    • (2004) Br. J. Pharmacol. , vol.142 , pp. 374-380
    • Bell, J.K.1    McQueen, D.S.2    Rees, J.L.3
  • 32
    • 0023220980 scopus 로고
    • Topical levocabastine, a selective H1 antagonist, in seasonal allergic rhinoconjunctivitis
    • Bende M and Pipkorn U (1987) Topical levocabastine, a selective H1 antagonist, in seasonal allergic rhinoconjunctivitis. Allergy 42: 512-515.
    • (1987) Allergy , vol.42 , pp. 512-515
    • Bende, M.1    Pipkorn, U.2
  • 34
    • 0025932114 scopus 로고
    • Management of the pruritus of cholestasis: Potential role of opiate antagonists
    • Bergasa NV and Jones EA (1991) Management of the pruritus of cholestasis: Potential role of opiate antagonists. Am. J. Gastroenterol. 86: 1404-1412.
    • (1991) Am. J. Gastroenterol. , vol.86 , pp. 1404-1412
    • Bergasa, N.V.1    Jones, E.A.2
  • 36
    • 33749181097 scopus 로고    scopus 로고
    • Impact of azelas-tine nasal spray on symptoms and quality of life compared with cetirizine oral tablets in patients with seasonal allergic rhinitis
    • Berger W, Hampel F, Jr., Bernstein J, Shah S, Sacks H and Meltzer EO (2006) Impact of azelas-tine nasal spray on symptoms and quality of life compared with cetirizine oral tablets in patients with seasonal allergic rhinitis. Ann. Allergy Asthma Immunol. 97: 375-381.
    • (2006) Ann. Allergy Asthma Immunol. , vol.97 , pp. 375-381
    • Berger, W.1    Hampel, F.2    Bernstein, J.3    Shah, S.4    Sacks, H.5    Meltzer, E.O.6
  • 37
    • 0036878326 scopus 로고    scopus 로고
    • Safety and efficacy of desloratadine 5 mg in asthma patients with seasonal allergic rhinitis and nasal congestion
    • Berger WE, Schenkel EJ and Mansfield LE (2002) Safety and efficacy of desloratadine 5 mg in asthma patients with seasonal allergic rhinitis and nasal congestion. Ann. Allergy Asthma Immunol. 89: 485-491.
    • (2002) Ann. Allergy Asthma Immunol. , vol.89 , pp. 485-491
    • Berger, W.E.1    Schenkel, E.J.2    Mansfield, L.E.3
  • 40
    • 0012034895 scopus 로고
    • The nature of the vaso-dilator con-stituents of certain tissue extracts
    • Best CH, Dale HH, Dudley HW and Thorpe WV (1927) The nature of the vaso-dilator con-stituents of certain tissue extracts. J. Physiol. 62: 397-417.
    • (1927) J. Physiol. , vol.62 , pp. 397-417
    • Best, C.H.1    Dale, H.H.2    Dudley, H.W.3    Thorpe, W.V.4
  • 41
    • 0000235411 scopus 로고
    • Experiments relating to the itch sensation, it’s peripheral mechanism, and central pathways
    • Bickford RG (1937) Experiments relating to the itch sensation, it’s peripheral mechanism, and central pathways. Clin. Sci. 3: 377-386.
    • (1937) Clin. Sci. , vol.3 , pp. 377-386
    • Bickford, R.G.1
  • 42
    • 12344324604 scopus 로고    scopus 로고
    • Efficacy and tolerability of newer antihistamines in the treatment of allergic conjunctivitis
    • Bielory L, Lien KW and Bigelsen S (2005) Efficacy and tolerability of newer antihistamines in the treatment of allergic conjunctivitis. Drugs 65: 215-228.
    • (2005) Drugs , vol.65 , pp. 215-228
    • Bielory, L.1    Lien, K.W.2    Bigelsen, S.3
  • 46
    • 79960703085 scopus 로고    scopus 로고
    • Molecular pharmacology of the four histamine receptors
    • Bongers G, de Esch I and Leurs R (2010) Molecular pharmacology of the four histamine receptors. Adv. Exp. Med. Biol. 709: 11-19.
    • (2010) Adv. Exp. Med. Biol. , vol.709 , pp. 11-19
    • Bongers, G.1    de Esch, I.2    Leurs, R.3
  • 47
    • 70350728830 scopus 로고    scopus 로고
    • Efficacy of olopatadine HCI 0.1%, ketotifen fumarate 0.025%, epinastine HCI 0.05%, emedastine 0.05% and fluorometholone acetate 0.1% ophthalmic solutions for seasonal allergic conjunctivitis: A placebo-controlled environmental trial
    • Borazan M, Karalezli A, Akova YA, Akman A, Kiyici H and Erbek SS (2009) Efficacy of olopatadine HCI 0.1%, ketotifen fumarate 0.025%, epinastine HCI 0.05%, emedastine 0.05% and fluorometholone acetate 0.1% ophthalmic solutions for seasonal allergic conjunctivitis: A placebo-controlled environmental trial. Acta Ophthalmol. 87: 549-554.
    • (2009) Acta Ophthalmol. , vol.87 , pp. 549-554
    • Borazan, M.1    Karalezli, A.2    Akova, Y.A.3    Akman, A.4    Kiyici, H.5    Erbek, S.S.6
  • 48
    • 0000813190 scopus 로고
    • Protective action of some phenolic ethers in histamine intoxica-tion
    • Bovet D and Staub AM (1937) Protective action of some phenolic ethers in histamine intoxica-tion. C. R. Seances Soc. Biol. Fil. 124: 547-549.
    • (1937) C. R. Seances Soc. Biol. Fil. , vol.124 , pp. 547-549
    • Bovet, D.1    Staub, A.M.2
  • 49
    • 33746150129 scopus 로고    scopus 로고
    • Allergy medication in Japanese volunteers: Treatment effect of single doses on nocturnal sleep architecture and next day residual effects
    • Boyle J, Eriksson M, Stanley N, Fujita T and Kumagi Y (2006) Allergy medication in Japanese volunteers: Treatment effect of single doses on nocturnal sleep architecture and next day residual effects. Curr. Med. Res. Opin. 22: 1343-1351.
    • (2006) Curr. Med. Res. Opin. , vol.22 , pp. 1343-1351
    • Boyle, J.1    Eriksson, M.2    Stanley, N.3    Fujita, T.4    Kumagi, Y.5
  • 50
    • 0029785454 scopus 로고    scopus 로고
    • Cetirizine versus hydroxyzine and placebo in chronic idiopathic urti-caria
    • Breneman DL (1996) Cetirizine versus hydroxyzine and placebo in chronic idiopathic urti-caria. Ann. Pharmacother. 30: 1075-1079.
    • (1996) Ann. Pharmacother. , vol.30 , pp. 1075-1079
    • Breneman, D.L.1
  • 51
    • 0006857423 scopus 로고
    • Observations on itching produced by cowhage, and on the part played by histamine as a mediator of the itch sensation
    • Broadbent JL (1953) Observations on itching produced by cowhage, and on the part played by histamine as a mediator of the itch sensation. Br. J. Pharmacol. Chemother. 8: 263-270.
    • (1953) Br. J. Pharmacol. Chemother. , vol.8 , pp. 263-270
    • Broadbent, J.L.1
  • 52
    • 0008213809 scopus 로고
    • Observations on histamine-induced pruritus and pain
    • Broadbent JL (1955) Observations on histamine-induced pruritus and pain. Br. J. Pharmacol. Chemother. 10: 183-185.
    • (1955) Br. J. Pharmacol. Chemother. , vol.10 , pp. 183-185
    • Broadbent, J.L.1
  • 53
    • 0021268032 scopus 로고
    • Mast cell degranulation in the evolution of acute eruptive guttate psoriasis vulgaris
    • Brody I (1984) Mast cell degranulation in the evolution of acute eruptive guttate psoriasis vulgaris. J. Invest. Dermatol. 82: 460-464.
    • (1984) J. Invest. Dermatol. , vol.82 , pp. 460-464
    • Brody, I.1
  • 54
    • 0019773872 scopus 로고
    • Protective effect of hydroxyzine and phenylpropanolamine in the challenged allergic nose
    • Brooks CD, Nelson A, Parzyck R and Maile MH (1981) Protective effect of hydroxyzine and phenylpropanolamine in the challenged allergic nose. Ann. Allergy 47: 316-319.
    • (1981) Ann. Allergy , vol.47 , pp. 316-319
    • Brooks, C.D.1    Nelson, A.2    Parzyck, R.3    Maile, M.H.4
  • 55
    • 0030054439 scopus 로고    scopus 로고
    • Efficacy of mizolastine, a new antihistamine, compared with placebo in the treatment of chronic idiopathic urti-caria
    • Brostoff J, Fitzharris P, Dunmore C, Theron M and Blondin P (1996) Efficacy of mizolastine, a new antihistamine, compared with placebo in the treatment of chronic idiopathic urti-caria. Allergy 51: 320-325.
    • (1996) Allergy , vol.51 , pp. 320-325
    • Brostoff, J.1    Fitzharris, P.2    Dunmore, C.3    Theron, M.4    Blondin, P.5
  • 56
    • 0344826048 scopus 로고    scopus 로고
    • Histamine induces cytoskeletal changes in human eosinophils via the H4 receptor
    • Buckland KF, Williams TJ and Conroy DM (2003) Histamine induces cytoskeletal changes in human eosinophils via the H4 receptor. Br. J. Pharmacol. 140: 1117-1127.
    • (2003) Br. J. Pharmacol. , vol.140 , pp. 1117-1127
    • Buckland, K.F.1    Williams, T.J.2    Conroy, D.M.3
  • 61
    • 0018657037 scopus 로고
    • Heterogeneity of histamine H1-receptors: Species variations in [3H]mepyramine binding of brain membranes
    • Chang RSL, Vihn TT and Snyder SH (1979) Heterogeneity of histamine H1-receptors: species variations in [3H]mepyramine binding of brain membranes. J. Neurochem. 32: 1653-1663.
    • (1979) J. Neurochem. , vol.32 , pp. 1653-1663
    • Chang, R.S.L.1    Vihn, T.T.2    Snyder, S.H.3
  • 65
    • 0034853358 scopus 로고    scopus 로고
    • Comparison of the effects of levocetiri-zine and loratadine on histamine-induced wheal, flare, and itch in human skin
    • Clough GF, Boutsiouki P and Church MK (2001) Comparison of the effects of levocetiri-zine and loratadine on histamine-induced wheal, flare, and itch in human skin. Allergy 56: 985-988.
    • (2001) Allergy , vol.56 , pp. 985-988
    • Clough, G.F.1    Boutsiouki, P.2    Church, M.K.3
  • 66
    • 84872450458 scopus 로고
    • A discussion of benadryl as an antihistamine substance
    • Code CF (1945) A discussion of benadryl as an antihistamine substance. Proc. Staff Meet. Mayo Clin. 20: 439-445.
    • (1945) Proc. Staff Meet. Mayo Clin. , vol.20 , pp. 439-445
    • Code, C.F.1
  • 67
  • 69
    • 0002539782 scopus 로고
    • Experimental histamine pruritis. I. Influence of physical and psychological factors on reactivity
    • Cormia FE (1952) Experimental histamine pruritis. I. Influence of physical and psychological factors on reactivity. J. Invest. Dermatol. 19: 21-34.
    • (1952) J. Invest. Dermatol. , vol.19 , pp. 21-34
    • Cormia, F.E.1
  • 70
    • 0011892840 scopus 로고
    • Proteolytic activity in development of pain and itching. Cutaneous reactions to bradykinin and kallikrein
    • Cormia FE and Dougherty JW (1960) Proteolytic activity in development of pain and itching. Cutaneous reactions to bradykinin and kallikrein. J. Invest. Dermatol. 35: 21-26.
    • (1960) J. Invest. Dermatol. , vol.35 , pp. 21-26
    • Cormia, F.E.1    Dougherty, J.W.2
  • 71
    • 84912199771 scopus 로고
    • Experimental histamine pruritus. III. Influence of drugs on the itch threshold
    • Cormia FE and Kuykendall V (1954) Experimental histamine pruritus. III. Influence of drugs on the itch threshold. A.M.A. Arch. Dermatol. Syphilol. 69: 206-218.
    • (1954) A.M.A. Arch. Dermatol. Syphilol. , vol.69 , pp. 206-218
    • Cormia, F.E.1    Kuykendall, V.2
  • 72
    • 0025820353 scopus 로고
    • Histamine-induced wheal, flare, and pruritus: Inhibition by cetirizine, terfenadine, and placebo
    • Coulie PJ, Ghys L and Rihoux JP (1991) Histamine-induced wheal, flare, and pruritus: Inhibition by cetirizine, terfenadine, and placebo. Drug Dev. Res. 23: 269-274.
    • (1991) Drug Dev. Res. , vol.23 , pp. 269-274
    • Coulie, P.J.1    Ghys, L.2    Rihoux, J.P.3
  • 73
    • 77949541373 scopus 로고    scopus 로고
    • The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation
    • Cowden JM, Zhang M, Dunford PJ and Thurmond RL (2010) The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation. J. Invest. Dermatol. 130: 1023-1033.
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 1023-1033
    • Cowden, J.M.1    Zhang, M.2    Dunford, P.J.3    Thurmond, R.L.4
  • 74
    • 0001695201 scopus 로고
    • Torsade de pointes after astemizole overdose
    • Craft TM (1986) Torsade de pointes after astemizole overdose. Br. Med. J. 292:660.
    • (1986) Br. Med. J. , vol.292 , pp. 660
    • Craft, T.M.1
  • 75
    • 0036861012 scopus 로고    scopus 로고
    • A comparison of the relative clinical efficacy of a single dose of ketotifen fumarate 0.025% ophthalmic solution versus placebo in inhibiting the signs and symp-toms of allergic rhinoconjunctivitis as induced by the conjunctival allergen challenge model
    • Crampton HJ (2002) A comparison of the relative clinical efficacy of a single dose of ketotifen fumarate 0.025% ophthalmic solution versus placebo in inhibiting the signs and symp-toms of allergic rhinoconjunctivitis as induced by the conjunctival allergen challenge model. Clin. Ther. 24: 1800-1808.
    • (2002) Clin. Ther. , vol.24 , pp. 1800-1808
    • Crampton, H.J.1
  • 76
    • 0041701533 scopus 로고    scopus 로고
    • Comparison of ketotifen fumarate ophthalmic solution alone, deslorata-dine alone, and their combination for inhibition of the signs and symptoms of seasonal allergic rhinoconjunctivitis in the conjunctival allergen challenge model: A double-masked, placebo- and active-controlled trial
    • Crampton HJ (2003) Comparison of ketotifen fumarate ophthalmic solution alone, deslorata-dine alone, and their combination for inhibition of the signs and symptoms of seasonal allergic rhinoconjunctivitis in the conjunctival allergen challenge model: A double-masked, placebo- and active-controlled trial. Clin. Ther. 25: 1975-1987.
    • (2003) Clin. Ther. , vol.25 , pp. 1975-1987
    • Crampton, H.J.1
  • 77
    • 0013650120 scopus 로고
    • Beta dimethylaminoethyl benzhydryl ether hydrochloride (benadryl) in treatment of urticaria
    • Curtis AC and Owens BB (1945) Beta dimethylaminoethyl benzhydryl ether hydrochloride (benadryl) in treatment of urticaria. Arch. Derm. Syphilol. 52: 239-242.
    • (1945) Arch. Derm. Syphilol. , vol.52 , pp. 239-242
    • Curtis, A.C.1    Owens, B.B.2
  • 78
    • 0025218656 scopus 로고
    • Rifampin relieves pruritus in children with cholestatic liver disease
    • Cynamon HA, Andres JM and Iafrate RP (1990) Rifampin relieves pruritus in children with cholestatic liver disease. Gastroenterology 98: 1013-1016.
    • (1990) Gastroenterology , vol.98 , pp. 1013-1016
    • Cynamon, H.A.1    Andres, J.M.2    Iafrate, R.P.3
  • 79
    • 0036205001 scopus 로고    scopus 로고
    • Randomized, double-masked, placebo-controlled comparison of the efficacy of emedastine difumarate 0.05% ophthalmic solution and ketotifen fumarate 0.025% ophthalmic solution in the human conjunctival allergen challenge model
    • D’Arienzo PA, Leonardi A and Bensch G (2002) Randomized, double-masked, placebo-controlled comparison of the efficacy of emedastine difumarate 0.05% ophthalmic solution and ketotifen fumarate 0.025% ophthalmic solution in the human conjunctival allergen challenge model. Clin. Ther. 24: 409-416.
    • (2002) Clin. Ther. , vol.24 , pp. 409-416
    • D’Arienzo, P.A.1    Leonardi, A.2    Bensch, G.3
  • 80
    • 49749157135 scopus 로고
    • Croonian lectures on some chemical factors in the control of the circulation
    • Dale HH (1929) Croonian lectures on some chemical factors in the control of the circulation. Lancet 213: 1233-1237.
    • (1929) Lancet , vol.213 , pp. 1233-1237
    • Dale, H.H.1
  • 82
    • 84944482644 scopus 로고
    • The physiological action of β-iminazolylethylamine
    • Dale HH and Laidlaw PP (1911) The physiological action of β-iminazolylethylamine. J. Physiol. 41: 318-344.
    • (1911) J. Physiol. , vol.41 , pp. 318-344
    • Dale, H.H.1    Laidlaw, P.P.2
  • 85
    • 0029813113 scopus 로고    scopus 로고
    • Correlations between histamine-induced wheal, flare and itch
    • Darsow U, Ring J, Scharein E and Bromm B (1996) Correlations between histamine-induced wheal, flare and itch. Arch. Dermatol. Res. 288: 436-441.
    • (1996) Arch. Dermatol. Res. , vol.288 , pp. 436-441
    • Darsow, U.1    Ring, J.2    Scharein, E.3    Bromm, B.4
  • 86
    • 67349165698 scopus 로고    scopus 로고
    • Relief of itch by scratching: State-dependent inhibition of primate spinothalamic tract neurons
    • Davidson S, Zhang X, Khasabov SG, Simone DA and Giesler GJ, Jr. (2009) Relief of itch by scratching: State-dependent inhibition of primate spinothalamic tract neurons. Nat. Neurosci. 12: 544-546.
    • (2009) Nat. Neurosci. , vol.12 , pp. 544-546
    • Davidson, S.1    Zhang, X.2    Khasabov, S.G.3    Simone, D.A.4    Giesler, G.J.5
  • 87
    • 34548617428 scopus 로고    scopus 로고
    • The itch-producing agents histamine and cowhage activate separate populations of primate spinothalamic tract neurons
    • Davidson S, Zhang X, Yoon CH, Khasabov SG, Simone DA and Giesler GJ, Jr. (2007) The itch-producing agents histamine and cowhage activate separate populations of primate spinothalamic tract neurons. J. Neurosci. 27: 10007-10014.
    • (2007) J. Neurosci. , vol.27 , pp. 10007-10014
    • Davidson, S.1    Zhang, X.2    Yoon, C.H.3    Khasabov, S.G.4    Simone, D.A.5    Giesler, G.J.6
  • 88
    • 0019185843 scopus 로고
    • Sensory responses of human skin to synthetic histamine analogs and histamine
    • Davies MG and Greaves MW (1980) Sensory responses of human skin to synthetic histamine analogs and histamine. Br. J. Clin. Pharmacol. 9: 461-465.
    • (1980) Br. J. Clin. Pharmacol. , vol.9 , pp. 461-465
    • Davies, M.G.1    Greaves, M.W.2
  • 89
    • 0018621879 scopus 로고
    • The efficacy of histamine antagonists as antipruritics in experimentally induced pruritus
    • Davies MG, Marks R, Horton RJ and Storari FE (1979) The efficacy of histamine antagonists as antipruritics in experimentally induced pruritus. Arch. Dermatol. Res. 266: 117-120.
    • (1979) Arch. Dermatol. Res. , vol.266 , pp. 117-120
    • Davies, M.G.1    Marks, R.2    Horton, R.J.3    Storari, F.E.4
  • 90
    • 33747161622 scopus 로고    scopus 로고
    • Treating itch in psoriasis
    • Dawn A and Yosipovitch G (2006) Treating itch in psoriasis. Dermatol. Nurs. 18: 227-233.
    • (2006) Dermatol. Nurs. , vol.18 , pp. 227-233
    • Dawn, A.1    Yosipovitch, G.2
  • 92
    • 84928017449 scopus 로고
    • Action de bases antagonistes de l’histamine sur quelques maladies liees a des reactions d’hypersensibilite
    • Decourt P (1942) Action de bases antagonistes de l’histamine sur quelques maladies liees a des reactions d’hypersensibilite. Bull. Mem. Soc. Med. Hop. Paris 58: 265-266.
    • (1942) Bull. Mem. Soc. Med. Hop. Paris , vol.58 , pp. 265-266
    • Decourt, P.1
  • 94
    • 33750976203 scopus 로고    scopus 로고
    • Significant impact of cutaneous T-cell lymphoma on patients’ quality of life: Results of a 2005 National Cutaneous Lymphoma Foundation Survey
    • Demierre MF, Gan S, Jones J and Miller DR (2006) Significant impact of cutaneous T-cell lymphoma on patients’ quality of life: Results of a 2005 National Cutaneous Lymphoma Foundation Survey. Cancer 107: 2504-2511.
    • (2006) Cancer , vol.107 , pp. 2504-2511
    • Demierre, M.F.1    Gan, S.2    Jones, J.3    Miller, D.R.4
  • 95
    • 70350464920 scopus 로고    scopus 로고
    • Interactions of hista-mine H1-receptor agonists and antagonists with the human histamine H4-receptor
    • Deml K-F, Beermann S, Neumann D, Strasser A and Seifert R (2009) Interactions of hista-mine H1-receptor agonists and antagonists with the human histamine H4-receptor. Mol. Pharmacol. 76: 1019-1030.
    • (2009) Mol. Pharmacol. , vol.76 , pp. 1019-1030
    • Deml, K.-F.1    Beermann, S.2    Neumann, D.3    Strasser, A.4    Seifert, R.5
  • 96
    • 0141921950 scopus 로고    scopus 로고
    • Comparison of the effects of desloratadine and levocetirizine on histamine-induced wheal, flare and itch in human skin
    • Denham KJ, Boutsiouki P, Clough GF and Church MK (2003) Comparison of the effects of desloratadine and levocetirizine on histamine-induced wheal, flare and itch in human skin. Inflamm. Res. 52: 424-427.
    • (2003) Inflamm. Res. , vol.52 , pp. 424-427
    • Denham, K.J.1    Boutsiouki, P.2    Clough, G.F.3    Church, M.K.4
  • 97
    • 79957580712 scopus 로고    scopus 로고
    • Histamine H4 receptor activation enhances LPS-induced IL-6 production in mast cells via ERK and PI3K activation
    • Desai P and Thurmond RL (2011) Histamine H4 receptor activation enhances LPS-induced IL-6 production in mast cells via ERK and PI3K activation. Eur. J. Immunol. 41: 1764-1773.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 1764-1773
    • Desai, P.1    Thurmond, R.L.2
  • 98
    • 0036669028 scopus 로고    scopus 로고
    • Long-term treatment with cetirizine of infants with atopic dermatitis: A multi-country, double-blind, randomized, placebo-controlled trial (the ETAC trial) over 18 months
    • Diepgen TL (2002) Long-term treatment with cetirizine of infants with atopic dermatitis: A multi-country, double-blind, randomized, placebo-controlled trial (the ETAC trial) over 18 months. Pediatr. Allergy Immunol. 13: 278-286.
    • (2002) Pediatr. Allergy Immunol. , vol.13 , pp. 278-286
    • Diepgen, T.L.1
  • 101
    • 0032586305 scopus 로고    scopus 로고
    • Comparison of the topical ocular antiallergic efficacy of emedastine 0.05% ophthalmic solution to ketorolac 0.5% ophthalmic solution in a clinical model of allergic conjunctivitis
    • Discepola M, Deschenes J and Abelson M (1999) Comparison of the topical ocular antiallergic efficacy of emedastine 0.05% ophthalmic solution to ketorolac 0.5% ophthalmic solution in a clinical model of allergic conjunctivitis. Acta Ophthalmol. Scand. Suppl. 228: 43-46.
    • (1999) Acta Ophthalmol. Scand. Suppl. , vol.228 , pp. 43-46
    • Discepola, M.1    Deschenes, J.2    Abelson, M.3
  • 102
    • 0016662061 scopus 로고
    • Reactions to aspirin and food additives in patients with chronic urticaria, including the physical urticarias
    • Doeglas HM (1975) Reactions to aspirin and food additives in patients with chronic urticaria, including the physical urticarias. Br. J. Dermatol. 93: 135-144.
    • (1975) Br. J. Dermatol. , vol.93 , pp. 135-144
    • Doeglas, H.M.1
  • 103
    • 0028131223 scopus 로고
    • Relief of pruritus in patients with atopic dermatitis after treatment with topical doxepin cream. The Doxepin Study Group
    • Drake LA, Fallon JD and Sober A (1994) Relief of pruritus in patients with atopic dermatitis after treatment with topical doxepin cream. The Doxepin Study Group. J. Am. Acad. Dermatol. 31: 613-616.
    • (1994) J. Am. Acad. Dermatol. , vol.31 , pp. 613-616
    • Drake, L.A.1    Fallon, J.D.2    Sober, A.3
  • 104
    • 0035061928 scopus 로고    scopus 로고
    • Central activation by histamine-induced itch: Analogies to pain processing: A correlational analysis of O-15 H2O positron emission tomography studies
    • Drzezga A, Darsow U, Treede RD, Siebner H, Frisch M, Munz F, Weilke F, Ring J, Schwaiger M and Bartenstein P (2001) Central activation by histamine-induced itch: Analogies to pain processing: A correlational analysis of O-15 H2O positron emission tomography studies. Pain 92: 295-305.
    • (2001) Pain , vol.92 , pp. 295-305
    • Drzezga, A.1    Darsow, U.2    Treede, R.D.3    Siebner, H.4    Frisch, M.5    Munz, F.6    Weilke, F.7    Ring, J.8    Schwaiger, M.9    Bartenstein, P.10
  • 105
    • 6544291728 scopus 로고    scopus 로고
    • Efficacy and safety of mizolastine 10 mg in a placebo-controlled comparison with loratadine in chronic idiopathic urticaria: Results of the MILOR Study
    • Dubertret L, Murrieta Aguttes M and Tonet J (1999) Efficacy and safety of mizolastine 10 mg in a placebo-controlled comparison with loratadine in chronic idiopathic urticaria: Results of the MILOR Study. J. Eur. Acad. Dermatol. Venereol. 12: 16-24.
    • (1999) J. Eur. Acad. Dermatol. Venereol. , vol.12 , pp. 16-24
    • Dubertret, L.1    Murrieta Aguttes, M.2    Tonet, J.3
  • 106
    • 0032896891 scopus 로고    scopus 로고
    • Second-generation antihistamines: The risk of ventricular arrhythmias
    • DuBuske LM (1999) Second-generation antihistamines: The risk of ventricular arrhythmias. Clin. Ther. 21: 281-295.
    • (1999) Clin. Ther. , vol.21 , pp. 281-295
    • DuBuske, L.M.1
  • 107
    • 33845924770 scopus 로고    scopus 로고
    • Histamine H4 receptor antagonists are superior to traditional antihistamines in the atten-uation of experimental pruritus
    • Dunford PJ, Williams KN, Desai PJ, Karlsson L, McQueen D and Thurmond RL (2007) Histamine H4 receptor antagonists are superior to traditional antihistamines in the atten-uation of experimental pruritus. J. Allergy Clin. Immunol. 119: 176-183.
    • (2007) J. Allergy Clin. Immunol. , vol.119 , pp. 176-183
    • Dunford, P.J.1    Williams, K.N.2    Desai, P.J.3    Karlsson, L.4    McQueen, D.5    Thurmond, R.L.6
  • 108
    • 0028021749 scopus 로고
    • Effect of terfenadine on human eosinophil and neu-trophil chemotactic response and generation of superoxide
    • Eda R, Townley RG and Hopp RJ (1994) Effect of terfenadine on human eosinophil and neu-trophil chemotactic response and generation of superoxide. Ann. Allergy 73: 154-160.
    • (1994) Ann. Allergy , vol.73 , pp. 154-160
    • Eda, R.1    Townley, R.G.2    Hopp, R.J.3
  • 112
    • 0027449440 scopus 로고
    • New activation model for the histamine H2 receptor, explaining the activity of the different classes of histamine H2 receptor ago-nists
    • Eriks JC, Van DGH and Timmerman H (1993) New activation model for the histamine H2 receptor, explaining the activity of the different classes of histamine H2 receptor ago-nists. Mol. Pharmacol. 44: 886-894.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 886-894
    • Eriks, J.C.1    Van, D.G.H.2    Timmerman, H.3
  • 113
    • 84943992324 scopus 로고
    • Use of histamine in the treatment of pruritus
    • Ernstene AC and Banks BM (1933) Use of histamine in the treatment of pruritus. J. Am. Med. Assoc. 100: 328-330.
    • (1933) J. Am. Med. Assoc. , vol.100 , pp. 328-330
    • Ernstene, A.C.1    Banks, B.M.2
  • 114
    • 0037648479 scopus 로고    scopus 로고
    • Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects
    • Esbenshade TA, Krueger KM, Miller TR, Kang CH, Denny LI, Witte DG, Yao BB et al. (2003) Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects. J. Pharmacol. Exp. Ther. 305: 887-896.
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 887-896
    • Esbenshade, T.A.1    Krueger, K.M.2    Miller, T.R.3    Kang, C.H.4    Denny, L.I.5    Witte, D.G.6    Yao, B.B.7
  • 115
    • 84861924163 scopus 로고    scopus 로고
    • Histamine H2-receptor antagonists for urticaria
    • Fedorowicz Z, van ZEJ and Hu N (2012) Histamine H2-receptor antagonists for urticaria. Cochrane Database Syst. Rev. 3:CD008596.
    • (2012) Cochrane Database Syst. Rev. , vol.3
    • Fedorowicz, Z.1    Hu, N.2
  • 116
    • 50349106790 scopus 로고
    • Relief of dermographism and other urticarias of hista-mine origin by a synthetic benzhydryl alkamine ether
    • Feinberg SM and Friedlaender S (1945) Relief of dermographism and other urticarias of hista-mine origin by a synthetic benzhydryl alkamine ether. J. Allergy 16: 296-298.
    • (1945) J. Allergy , vol.16 , pp. 296-298
    • Feinberg, S.M.1    Friedlaender, S.2
  • 117
    • 0019495868 scopus 로고
    • Studies on pruritogenic and histamine-releasing effects of some putative peptide neurotransmitters
    • Fjellner B and Haegermark O (1981) Studies on pruritogenic and histamine-releasing effects of some putative peptide neurotransmitters. Acta Derm. Venereol. 61: 245-250.
    • (1981) Acta Derm. Venereol. , vol.61 , pp. 245-250
    • Fjellner, B.1    Haegermark, O.2
  • 118
    • 0021885573 scopus 로고
    • Experimental pruritus evoked by platelet activating factor (PAF-acether) in human skin
    • Fjellner B and Hagermark O (1985) Experimental pruritus evoked by platelet activating factor (PAF-acether) in human skin. Acta Derm. Venereol. 65: 409-412.
    • (1985) Acta Derm. Venereol. , vol.65 , pp. 409-412
    • Fjellner, B.1    Hagermark, O.2
  • 120
    • 0035191794 scopus 로고    scopus 로고
    • Effects of cetirizine and epinastine on the skin response to histamine iontophoresis
    • Furue M, Terao H and Koga T (2001) Effects of cetirizine and epinastine on the skin response to histamine iontophoresis. J. Dermatol. Sci. 25: 59-63.
    • (2001) J. Dermatol. Sci. , vol.25 , pp. 59-63
    • Furue, M.1    Terao, H.2    Koga, T.3
  • 121
    • 34447642715 scopus 로고    scopus 로고
    • The evasive nature of drug efficacy: Implications for drug discovery
    • Galandrin S, Oligny-Longpré G and Bouvier M (2007) The evasive nature of drug efficacy: Implications for drug discovery. Trends Pharmacol. Sci. 28: 423-430.
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 423-430
    • Galandrin, S.1    Oligny-Longpré, G.2    Bouvier, M.3
  • 122
    • 84871633754 scopus 로고    scopus 로고
    • Alcaftadine, a new antihistamine with combined antagonist activity at histamine H1, H2, and H4 receptors
    • Gallois-Bernos AC and Thurmond RL (2012) Alcaftadine, a new antihistamine with combined antagonist activity at histamine H1, H2, and H4 receptors. J. Receptor Ligand Channel Res. 2012: 9-20.
    • (2012) J. Receptor Ligand Channel Res. , vol.2012 , pp. 9-20
    • Gallois-Bernos, A.C.1    Thurmond, R.L.2
  • 124
    • 0038208099 scopus 로고    scopus 로고
    • Ketotifen fumarate and olopatadine hydrochloride in the treatment of allergic conjunctivitis: A real-world comparison of efficacy and ocular comfort
    • Ganz M, Koll E, Gausche J, Detjen P and Orfan N (2003) Ketotifen fumarate and olopatadine hydrochloride in the treatment of allergic conjunctivitis: A real-world comparison of efficacy and ocular comfort. Adv. Ther. 20: 79-91.
    • (2003) Adv. Ther. , vol.20 , pp. 79-91
    • Ganz, M.1    Koll, E.2    Gausche, J.3    Detjen, P.4    Orfan, N.5
  • 125
    • 33645551062 scopus 로고    scopus 로고
    • Compared pharmacology of human histamine H3 and H4 receptors: Structure-activity relationships of histamine derivatives
    • Gbahou F, Vincent L, Humbert-Claude M, Tardivel-Lacombe J, Chabret C and Arrang J-M (2006) Compared pharmacology of human histamine H3 and H4 receptors: Structure-activity relationships of histamine derivatives. Br. J. Pharmacol. 147: 744-754.
    • (2006) Br. J. Pharmacol. , vol.147 , pp. 744-754
    • Gbahou, F.1    Vincent, L.2    Humbert-Claude, M.3    Tardivel-Lacombe, J.4    Chabret, C.5    Arrang, J.-M.6
  • 126
    • 0030919042 scopus 로고    scopus 로고
    • Fluticasone propionate aqueous nasal spray compared with oral loratadine in patients with seasonal allergic rhinitis
    • Gehanno P and Desfougeres JL (1997) Fluticasone propionate aqueous nasal spray compared with oral loratadine in patients with seasonal allergic rhinitis. Allergy 52: 445-450.
    • (1997) Allergy , vol.52 , pp. 445-450
    • Gehanno, P.1    Desfougeres, J.L.2
  • 127
    • 0023846078 scopus 로고
    • Treatment of pruritus in primary biliary cirrhosis with rifampin. Results of a double-blind, crossover, randomized trial
    • Ghent CN and Carruthers SG (1988) Treatment of pruritus in primary biliary cirrhosis with rifampin. Results of a double-blind, crossover, randomized trial. Gastroenterology 94: 488-493.
    • (1988) Gastroenterology , vol.94 , pp. 488-493
    • Ghent, C.N.1    Carruthers, S.G.2
  • 128
    • 0034524504 scopus 로고    scopus 로고
    • Comparison of azelastine eye drops with levocabastine eye drops in the treatment of seasonal allergic conjunctivitis
    • Giede C, Metzenauer P, Petzold U and Ellers-Lenz B (2000) Comparison of azelastine eye drops with levocabastine eye drops in the treatment of seasonal allergic conjunctivitis. Curr. Med. Res. Opin. 16: 153-163.
    • (2000) Curr. Med. Res. Opin. , vol.16 , pp. 153-163
    • Giede, C.1    Metzenauer, P.2    Petzold, U.3    Ellers-Lenz, B.4
  • 129
    • 0036153865 scopus 로고    scopus 로고
    • Binding characteristics of cetirizine and levocetirizine to human H(1) histamine receptors: Contribution of Lys(191) and Thr(194)
    • Gillard M, Van Der Perren C, Moguilevsky N, Massingham R and Chatelain P (2002) Binding characteristics of cetirizine and levocetirizine to human H(1) histamine receptors: Contribution of Lys(191) and Thr(194). Mol. Pharmacol. 61: 391-399.
    • (2002) Mol. Pharmacol. , vol.61 , pp. 391-399
    • Gillard, M.1    Van Der Perren, C.2    Moguilevsky, N.3    Massingham, R.4    Chatelain, P.5
  • 130
    • 0034826856 scopus 로고    scopus 로고
    • Effects of supratherapeutic doses of ebastine and terfenadine on the QT interval
    • Gillen MS, Miller B, Chaikin P and Morganroth J (2001) Effects of supratherapeutic doses of ebastine and terfenadine on the QT interval. Br. J. Clin. Pharmacol. 52: 201-204.
    • (2001) Br. J. Clin. Pharmacol. , vol.52 , pp. 201-204
    • Gillen, M.S.1    Miller, B.2    Chaikin, P.3    Morganroth, J.4
  • 131
    • 68749113079 scopus 로고    scopus 로고
    • The use of a responder analysis to iden-tify clinically meaningful differences in chronic urticaria patients following placebo- controlled treatment with rupatadine 10 and 20 mg
    • Gimenez-Arnau A, Izquierdo I and Maurer M (2009) The use of a responder analysis to iden-tify clinically meaningful differences in chronic urticaria patients following placebo- controlled treatment with rupatadine 10 and 20 mg. J. Eur. Acad. Dermatol. Venereol. 23: 1088-1091.
    • (2009) J. Eur. Acad. Dermatol. Venereol. , vol.23 , pp. 1088-1091
    • Gimenez-Arnau, A.1    Izquierdo, I.2    Maurer, M.3
  • 133
    • 0025020351 scopus 로고
    • Raised histamine concentrations in chronic cholestatic liver disease
    • Gittlen SD, Schulman ES and Maddrey WC (1990) Raised histamine concentrations in chronic cholestatic liver disease. Gut 31: 96-99.
    • (1990) Gut , vol.31 , pp. 96-99
    • Gittlen, S.D.1    Schulman, E.S.2    Maddrey, W.C.3
  • 134
    • 60249084148 scopus 로고    scopus 로고
    • Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: Randomised, double-blind, placebo-controlled, crossover trial
    • Gottlieb A, Menter A, Mendelsohn A, Shen YK, Li S, Guzzo C, Fretzin S, Kunynetz R and Kavanaugh A (2009) Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: Randomised, double-blind, placebo-controlled, crossover trial. Lancet 373: 633-640.
    • (2009) Lancet , vol.373 , pp. 633-640
    • Gottlieb, A.1    Menter, A.2    Mendelsohn, A.3    Shen, Y.K.4    Li, S.5    Guzzo, C.6    Fretzin, S.7    Kunynetz, R.8    Kavanaugh, A.9
  • 136
    • 0001836671 scopus 로고
    • Neural mechanisms involved in itch, itchy skin, and tickle sensations
    • Graham DT, Goodell H and Wolff HG (1951) Neural mechanisms involved in itch, itchy skin, and tickle sensations. J. Clin. Invest. 30: 37-49.
    • (1951) J. Clin. Invest. , vol.30 , pp. 37-49
    • Graham, D.T.1    Goodell, H.2    Wolff, H.G.3
  • 137
    • 0029653998 scopus 로고
    • Chronic urticaria
    • Greaves MW (1995) Chronic urticaria. N. Engl. J. Med. 332: 1767-1772.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1767-1772
    • Greaves, M.W.1
  • 138
    • 79251574323 scopus 로고    scopus 로고
    • Evaluation of alcaftadine 0.25% ophthalmic solution in acute allergic conjunctivitis at 15 minutes and 16 hours after instillation versus placebo and olopatadine 0.1%
    • Greiner JV, Edwards-Swanson K and Ingerman A (2011) Evaluation of alcaftadine 0.25% ophthalmic solution in acute allergic conjunctivitis at 15 minutes and 16 hours after instillation versus placebo and olopatadine 0.1%. Clin. Ophthalmol. 5: 87-93.
    • (2011) Clin. Ophthalmol. , vol.5 , pp. 87-93
    • Greiner, J.V.1    Edwards-Swanson, K.2    Ingerman, A.3
  • 139
    • 0042201984 scopus 로고    scopus 로고
    • A placebo-controlled comparison of ketotifen fumarate and nedocromil sodium ophthalmic solutions for the prevention of ocular itching with the conjunctival allergen challenge model
    • Greiner JV and Minno G (2003) A placebo-controlled comparison of ketotifen fumarate and nedocromil sodium ophthalmic solutions for the prevention of ocular itching with the conjunctival allergen challenge model. Clin. Ther. 25: 1988-2005.
    • (2003) Clin. Ther. , vol.25 , pp. 1988-2005
    • Greiner, J.V.1    Minno, G.2
  • 140
    • 80053374621 scopus 로고    scopus 로고
    • The histamine H4 receptor is highly expressed on plasmacytoid dendritic cells in psoriasis and his-tamine regulates their cytokine production and migration
    • Gschwandtner M, Mommert S, Koether B, Werfel T and Gutzmer R (2011a) The histamine H4 receptor is highly expressed on plasmacytoid dendritic cells in psoriasis and his-tamine regulates their cytokine production and migration. J. Invest. Dermatol. 131: 1668-1676.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 1668-1676
    • Gschwandtner, M.1    Mommert, S.2    Koether, B.3    Werfel, T.4    Gutzmer, R.5
  • 141
    • 78650028541 scopus 로고    scopus 로고
    • Histamine H4 receptor acti-vation on human slan-dendritic cells down-regulates their pro-inflammatory capacity
    • Gschwandtner M, Schaekel K, Werfel T and Gutzmer R (2011b) Histamine H4 receptor acti-vation on human slan-dendritic cells down-regulates their pro-inflammatory capacity. Immunology 132: 49-56.
    • (2011) Immunology , vol.132 , pp. 49-56
    • Gschwandtner, M.1    Schaekel, K.2    Werfel, T.3    Gutzmer, R.4
  • 143
    • 17844385099 scopus 로고    scopus 로고
    • Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates che-motaxis in human monocyte-derived dendritic cells
    • Gutzmer R, Diestel C, Mommert S, Koether B, Stark H, Wittmann M and Werfel T (2005) Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates che-motaxis in human monocyte-derived dendritic cells. J. Immunol. 174: 5224-5232.
    • (2005) J. Immunol. , vol.174 , pp. 5224-5232
    • Gutzmer, R.1    Diestel, C.2    Mommert, S.3    Koether, B.4    Stark, H.5    Wittmann, M.6    Werfel, T.7
  • 146
    • 0015801788 scopus 로고
    • Influence of antihistamines, sedatives, and aspirin on experimental itch
    • Hagermark O (1973) Influence of antihistamines, sedatives, and aspirin on experimental itch. Acta Derm. Venereol. 53: 363-368.
    • (1973) Acta Derm. Venereol. , vol.53 , pp. 363-368
    • Hagermark, O.1
  • 147
    • 0016261283 scopus 로고
    • Studies on experimental itch induced by kallikrein and bradykinin
    • Hagermark O (1974) Studies on experimental itch induced by kallikrein and bradykinin. Acta Derm. Venereol. 54: 397-400.
    • (1974) Acta Derm. Venereol. , vol.54 , pp. 397-400
    • Hagermark, O.1
  • 148
    • 0018253625 scopus 로고
    • Flare and itch induced by substance P in human skin
    • Hagermark O, Hokfelt T and Pernow B (1978) Flare and itch induced by substance P in human skin. J. Invest. Dermatol. 71: 233-235.
    • (1978) J. Invest. Dermatol. , vol.71 , pp. 233-235
    • Hagermark, O.1    Hokfelt, T.2    Pernow, B.3
  • 149
    • 0015445043 scopus 로고
    • Experimental itch in human skin elicited by rat mast cell chymase
    • Hagermark O, Rajka G and Bergvist U (1972) Experimental itch in human skin elicited by rat mast cell chymase. Acta Derm. Venereol. 52: 125-128.
    • (1972) Acta Derm. Venereol. , vol.52 , pp. 125-128
    • Hagermark, O.1    Rajka, G.2    Bergvist, U.3
  • 150
    • 0018747625 scopus 로고
    • Effects of histamine receptor antago-nists on histamine-induced responses in human skin
    • Hagermark O, Strandberg K and Gronneberg R (1979) Effects of histamine receptor antago-nists on histamine-induced responses in human skin. Acta Derm. Venereol. 59: 297-300.
    • (1979) Acta Derm. Venereol. , vol.59 , pp. 297-300
    • Hagermark, O.1    Strandberg, K.2    Gronneberg, R.3
  • 151
  • 152
    • 0142059246 scopus 로고    scopus 로고
    • Fexofenadine hydrochloride, 180 mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis
    • Hampel F, Ratner P, Mansfield L, Meeves S, Liao Y and Georges G (2003) Fexofenadine hydrochloride, 180 mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis. Ann. Allergy Asthma Immunol. 91: 354-361.
    • (2003) Ann. Allergy Asthma Immunol. , vol.91 , pp. 354-361
    • Hampel, F.1    Ratner, P.2    Mansfield, L.3    Meeves, S.4    Liao, Y.5    Georges, G.6
  • 154
    • 1342290811 scopus 로고    scopus 로고
    • Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria
    • Handa S, Dogra S and Kumar B (2004) Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria. J. Dermatolog. Treat. 15: 55-57.
    • (2004) J. Dermatolog. Treat. , vol.15 , pp. 55-57
    • Handa, S.1    Dogra, S.2    Kumar, B.3
  • 155
    • 0025743390 scopus 로고
    • Discharge patterns of human C-fibers induced by itching and burning stimuli
    • Handwerker HO, Forster C and Kirchhoff C (1991) Discharge patterns of human C-fibers induced by itching and burning stimuli. J. Neurophysiol. 66: 307-315.
    • (1991) J. Neurophysiol. , vol.66 , pp. 307-315
    • Handwerker, H.O.1    Forster, C.2    Kirchhoff, C.3
  • 156
    • 0020557948 scopus 로고
    • Effect of a new potent H2-receptor antagonist 3[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]-N2-sulfamoylpropionami-dine (YM-11170) on gastric mucosal histamine-sensitive adenylate cyclase from guinea pig
    • Harada M, Terai M and Maeno H (1983) Effect of a new potent H2-receptor antagonist 3[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]-N2-sulfamoylpropionami-dine (YM-11170) on gastric mucosal histamine-sensitive adenylate cyclase from guinea pig. Biochem. Pharmacol. 32: 1635-1640.
    • (1983) Biochem. Pharmacol. , vol.32 , pp. 1635-1640
    • Harada, M.1    Terai, M.2    Maeno, H.3
  • 157
    • 0022971336 scopus 로고
    • The effects of combined H1 and H2 histamine antagonists on alterations in nasal airflow resistance induced by topi-cal histamine provocation
    • Havas TE, Cole P, Parker L, Oprysk D and Ayiomamitis A (1986) The effects of combined H1 and H2 histamine antagonists on alterations in nasal airflow resistance induced by topi-cal histamine provocation. J. Allergy Clin. Immunol. 78: 856-860.
    • (1986) J. Allergy Clin. Immunol. , vol.78 , pp. 856-860
    • Havas, T.E.1    Cole, P.2    Parker, L.3    Oprysk, D.4    Ayiomamitis, A.5
  • 158
    • 35348819366 scopus 로고    scopus 로고
    • Itch induced by a novel method leads to limbic deactivations a functional MRI study
    • Herde L, Forster C, Strupf M and Handwerker HO (2007) Itch induced by a novel method leads to limbic deactivations a functional MRI study. J. Neurophysiol. 98: 2347-2356.
    • (2007) J. Neurophysiol. , vol.98 , pp. 2347-2356
    • Herde, L.1    Forster, C.2    Strupf, M.3    Handwerker, H.O.4
  • 159
    • 0016811160 scopus 로고
    • Itching: The pathophysiology of pruritus
    • Herndon JH, Jr. (1975) Itching: The pathophysiology of pruritus. Int. J. Dermatol. 14: 465-484.
    • (1975) Int. J. Dermatol. , vol.14 , pp. 465-484
    • Herndon, J.H.1
  • 161
    • 0031976232 scopus 로고    scopus 로고
    • Histamine and cutaneous noci-ception: Histamine-induced responses in patients with atopic eczema, psoriasis and urti-caria
    • Heyer G, Koppert W, Martus P and Handwerker HO (1998) Histamine and cutaneous noci-ception: histamine-induced responses in patients with atopic eczema, psoriasis and urti-caria. Acta Derm. Venereol. 78: 123-126.
    • (1998) Acta Derm. Venereol. , vol.78 , pp. 123-126
    • Heyer, G.1    Koppert, W.2    Martus, P.3    Handwerker, H.O.4
  • 162
    • 0029118640 scopus 로고
    • Effect of terfenadine and budesonide on nasal symptoms, olfaction, and nasal airway patency following allergen challenge
    • Hilberg O (1995) Effect of terfenadine and budesonide on nasal symptoms, olfaction, and nasal airway patency following allergen challenge. Allergy 50: 683-688.
    • (1995) Allergy , vol.50 , pp. 683-688
    • Hilberg, O.1
  • 163
    • 0028948833 scopus 로고
    • Nasal histamine challenge in nonallergic and allergic subjects evaluated by acoustic rhinometry
    • Hilberg O, Grymer LF and Pedersen OF (1995) Nasal histamine challenge in nonallergic and allergic subjects evaluated by acoustic rhinometry. Allergy 50: 166-173.
    • (1995) Allergy , vol.50 , pp. 166-173
    • Hilberg, O.1    Grymer, L.F.2    Pedersen, O.F.3
  • 164
    • 0032799404 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled investigation of the effects of fexofenadine, loratadine and promethazine on cognitive and psychomotor function
    • Hindmarch I, Shamsi Z, Stanley N and Fairweather DB (1999) A double-blind, placebo-controlled investigation of the effects of fexofenadine, loratadine and promethazine on cognitive and psychomotor function. Br. J. Clin. Pharmacol. 48: 200-206.
    • (1999) Br. J. Clin. Pharmacol. , vol.48 , pp. 200-206
    • Hindmarch, I.1    Shamsi, Z.2    Stanley, N.3    Fairweather, D.B.4
  • 166
    • 0031970562 scopus 로고    scopus 로고
    • Dose-dependent protection by azelastine eye drops against pollen-induced allergic conjunctivitis. A double-blind, placebo-controlled study
    • Horak F, Berger UE, Menapace R, Toth J, Stubner PU and Marks B (1998) Dose-dependent protection by azelastine eye drops against pollen-induced allergic conjunctivitis. A double-blind, placebo-controlled study. Arzneimittelforschung. 48: 379-384.
    • (1998) Arzneimittelforschung. , vol.48 , pp. 379-384
    • Horak, F.1    Berger, U.E.2    Menapace, R.3    Toth, J.4    Stubner, P.U.5    Marks, B.6
  • 168
    • 33751016799 scopus 로고    scopus 로고
    • Bradykinin is a potent pruritogen in atopic dermatitis: A switch from pain to itch
    • Hosogi M, Schmelz M, Miyachi Y and Ikoma A (2006) Bradykinin is a potent pruritogen in atopic dermatitis: A switch from pain to itch. Pain 126: 16-23.
    • (2006) Pain , vol.126 , pp. 16-23
    • Hosogi, M.1    Schmelz, M.2    Miyachi, Y.3    Ikoma, A.4
  • 169
  • 170
    • 0141543889 scopus 로고    scopus 로고
    • Involvement of histamine H3 receptors in scratching behavior in mast cell-deficient mice
    • Hossen MA, Sugimoto Y, Kayasuga R and Kamei C (2003) Involvement of histamine H3 receptors in scratching behavior in mast cell-deficient mice. Br. J. Dermatol. 149: 17-22.
    • (2003) Br. J. Dermatol. , vol.149 , pp. 17-22
    • Hossen, M.A.1    Sugimoto, Y.2    Kayasuga, R.3    Kamei, C.4
  • 171
    • 0035119027 scopus 로고    scopus 로고
    • Genomics meets histamine receptors: New subtypes, new receptors
    • Hough LB (2001) Genomics meets histamine receptors: New subtypes, new receptors. Mol. Pharmacol. 59: 415-419.
    • (2001) Mol. Pharmacol. , vol.59 , pp. 415-419
    • Hough, L.B.1
  • 172
    • 0032711088 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine hydrochloride (120 and 180 mg once daily) and cetirizine in seasonal allergic rhinitis
    • Howarth PH, Stern MA, Roi L, Reynolds R and Bousquet J (1999) Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine hydrochloride (120 and 180 mg once daily) and cetirizine in seasonal allergic rhinitis. J. Allergy Clin. Immunol. 104: 927-933.
    • (1999) J. Allergy Clin. Immunol. , vol.104 , pp. 927-933
    • Howarth, P.H.1    Stern, M.A.2    Roi, L.3    Reynolds, R.4    Bousquet, J.5
  • 175
    • 35248869253 scopus 로고    scopus 로고
    • Levocetirizine does not prolong the QT/QTc interval in healthy subjects: Results from a thorough QT study
    • Hulhoven R, Rosillon D, Letiexhe M, Meeus MA, Daoust A and Stockis A (2007) Levocetirizine does not prolong the QT/QTc interval in healthy subjects: Results from a thorough QT study. Eur. J. Clin. Pharmacol. 63: 1011-1017.
    • (2007) Eur. J. Clin. Pharmacol. , vol.63 , pp. 1011-1017
    • Hulhoven, R.1    Rosillon, D.2    Letiexhe, M.3    Meeus, M.A.4    Daoust, A.5    Stockis, A.6
  • 176
    • 55949113652 scopus 로고    scopus 로고
    • Comparative study of histamine H4 receptor expression in human dermal fibroblasts
    • Ikawa Y, Shiba K, Ohki E, Mutoh N, Suzuki M, Sato H and Ueno K (2008) Comparative study of histamine H4 receptor expression in human dermal fibroblasts. J. Toxicol. Sci. 33: 503-508.
    • (2008) J. Toxicol. Sci. , vol.33 , pp. 503-508
    • Ikawa, Y.1    Shiba, K.2    Ohki, E.3    Mutoh, N.4    Suzuki, M.5    Sato, H.6    Ueno, K.7
  • 177
    • 67749103836 scopus 로고    scopus 로고
    • Analysis of the mechanism for the development of allergic skin inflammation and the application for its treatment: Mechanisms and management of itch in atopic dermatitis
    • Ikoma A (2009) Analysis of the mechanism for the development of allergic skin inflammation and the application for its treatment: Mechanisms and management of itch in atopic dermatitis. J. Pharmacol. Sci. 110: 265-269.
    • (2009) J. Pharmacol. Sci. , vol.110 , pp. 265-269
    • Ikoma, A.1
  • 178
    • 0038343109 scopus 로고    scopus 로고
    • Comparison of the efficacy and tolerability of topically administered azelastine, sodium cromoglycate and placebo in the treatment of seasonal allergic conjunctivitis and rhino-conjunctivitis
    • James IG, Campbell LM, Harrison JM, Fell PJ, Ellers-Lenz B and Petzold U (2003) Comparison of the efficacy and tolerability of topically administered azelastine, sodium cromoglycate and placebo in the treatment of seasonal allergic conjunctivitis and rhino-conjunctivitis. Curr. Med. Res. Opin. 19: 313-320.
    • (2003) Curr. Med. Res. Opin. , vol.19 , pp. 313-320
    • James, I.G.1    Campbell, L.M.2    Harrison, J.M.3    Fell, P.J.4    Ellers-Lenz, B.5    Petzold, U.6
  • 182
    • 0014176410 scopus 로고
    • Localization and content of histamine in normal and diseased skin
    • Juhlin L (1967) Localization and content of histamine in normal and diseased skin. Acta Derm. Venereol. 47: 383-391.
    • (1967) Acta Derm. Venereol. , vol.47 , pp. 383-391
    • Juhlin, L.1
  • 183
    • 1342269550 scopus 로고    scopus 로고
    • Inhibition of cold urticaria by desloratadine
    • Juhlin L (2004) Inhibition of cold urticaria by desloratadine. J. Dermatol. Treat. 15: 51-59.
    • (2004) J. Dermatol. Treat. , vol.15 , pp. 51-59
    • Juhlin, L.1
  • 184
    • 0029760332 scopus 로고    scopus 로고
    • Double-blind multicentre comparative study of ebastine, terfenadine and placebo in the treatment of chronic idiopathic urticaria in adults
    • Kalis B (1996) Double-blind multicentre comparative study of ebastine, terfenadine and placebo in the treatment of chronic idiopathic urticaria in adults. Drugs 52 Suppl 1:30-34.
    • (1996) Drugs , vol.52 , pp. 30-34
    • Kalis, B.1
  • 185
    • 0025607772 scopus 로고
    • Urticaria: Clinical efficacy of cetirizine in comparison with hydroxyzine and placebo
    • Kalivas J, Breneman D, Tharp M, Bruce S and Bigby M (1990) Urticaria: Clinical efficacy of cetirizine in comparison with hydroxyzine and placebo. J. Allergy Clin. Immunol. 86: 1014-1018.
    • (1990) J. Allergy Clin. Immunol. , vol.86 , pp. 1014-1018
    • Kalivas, J.1    Breneman, D.2    Tharp, M.3    Bruce, S.4    Bigby, M.5
  • 186
    • 34548548827 scopus 로고    scopus 로고
    • Increasing the dose of cetirizine may lead to better control of chronic idiopathic urticaria: An open study of 21 patients
    • Kameyoshi Y, Tanaka T, Mihara S, Takahagi S, Niimi N and Hide M (2007) Increasing the dose of cetirizine may lead to better control of chronic idiopathic urticaria: An open study of 21 patients. Br. J. Dermatol. 157: 803-804.
    • (2007) Br. J. Dermatol. , vol.157 , pp. 803-804
    • Kameyoshi, Y.1    Tanaka, T.2    Mihara, S.3    Takahagi, S.4    Niimi, N.5    Hide, M.6
  • 187
    • 0036651571 scopus 로고    scopus 로고
    • Chronic urticaria-New concepts regarding pathogenesis and treatment
    • Kaplan AP (2002) Chronic urticaria-New concepts regarding pathogenesis and treatment. Curr. Allergy Asthma Rep. 2: 263-264.
    • (2002) Curr. Allergy Asthma Rep. , vol.2 , pp. 263-264
    • Kaplan, A.P.1
  • 188
    • 66149092706 scopus 로고    scopus 로고
    • Pathogenesis of chronic urticaria
    • Kaplan AP and Greaves M (2009) Pathogenesis of chronic urticaria. Clin. Exp. Allergy 39: 777-787.
    • (2009) Clin. Exp. Allergy , vol.39 , pp. 777-787
    • Kaplan, A.P.1    Greaves, M.2
  • 189
    • 0018154895 scopus 로고
    • Assessment of tissue fluid histamine levels in patients with urticaria
    • Kaplan AP, Horakova Z and Katz SI (1978) Assessment of tissue fluid histamine levels in patients with urticaria. J. Allergy Clin. Immunol. 61: 350-354.
    • (1978) J. Allergy Clin. Immunol. , vol.61 , pp. 350-354
    • Kaplan, A.P.1    Horakova, Z.2    Katz, S.I.3
  • 190
    • 20544453784 scopus 로고    scopus 로고
    • Once-daily fexofenadine treatment for chronic idiopathic urticaria: A multicenter, randomized, double-blind, placebo-controlled study
    • Kaplan AP, Spector SL, Meeves S, Liao Y, Varghese ST and Georges G (2005) Once-daily fexofenadine treatment for chronic idiopathic urticaria: A multicenter, randomized, double-blind, placebo-controlled study. Ann. Allergy Asthma Immunol. 94: 662-669.
    • (2005) Ann. Allergy Asthma Immunol. , vol.94 , pp. 662-669
    • Kaplan, A.P.1    Spector, S.L.2    Meeves, S.3    Liao, Y.4    Varghese, S.T.5    Georges, G.6
  • 192
    • 0036111175 scopus 로고    scopus 로고
    • Comparison of ceti-rizine, ebastine and loratadine in the treatment of immediate mosquito-bite allergy
    • Karppinen A, Kautiainen H, Petman L, Burri P and Reunala T (2002) Comparison of ceti-rizine, ebastine and loratadine in the treatment of immediate mosquito-bite allergy. Allergy 57: 534-537.
    • (2002) Allergy , vol.57 , pp. 534-537
    • Karppinen, A.1    Kautiainen, H.2    Petman, L.3    Burri, P.4    Reunala, T.5
  • 194
    • 33644843424 scopus 로고    scopus 로고
    • Fexofenadine, an H1-receptor antag-onist, partially but rapidly inhibits the itch of contact dermatitis induced by diphenylcy-clopropenone in patients with alopecia areata
    • Katagiri K, Arakawa S, Hatano Y and Fujiwara S (2006) Fexofenadine, an H1-receptor antag-onist, partially but rapidly inhibits the itch of contact dermatitis induced by diphenylcy-clopropenone in patients with alopecia areata. J. Dermatol. 33: 75-79.
    • (2006) J. Dermatol. , vol.33 , pp. 75-79
    • Katagiri, K.1    Arakawa, S.2    Hatano, Y.3    Fujiwara, S.4
  • 195
    • 18744390020 scopus 로고    scopus 로고
    • A com-parison of the efficacy and tolerability of olopatadine hydrochloride 0.1% ophthalmic solution and cromolyn sodium 2% ophthalmic solution in seasonal allergic conjunctivi-tis
    • Katelaris CH, Ciprandi G, Missotten L, Turner FD, Bertin D and Berdeaux G (2002) A com-parison of the efficacy and tolerability of olopatadine hydrochloride 0.1% ophthalmic solution and cromolyn sodium 2% ophthalmic solution in seasonal allergic conjunctivi-tis. Clin. Ther. 24: 1561-1575.
    • (2002) Clin. Ther. , vol.24 , pp. 1561-1575
    • Katelaris, C.H.1    Ciprandi, G.2    Missotten, L.3    Turner, F.D.4    Bertin, D.5    Berdeaux, G.6
  • 196
    • 0030821786 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic evaluation of central effect of the novel antiallergic agent bepotastine besilate
    • Kato M, Nishida A, Aga Y, Kita J, Kudo Y, Narita H and Endo T (1997) Pharmacokinetic and pharmacodynamic evaluation of central effect of the novel antiallergic agent bepotastine besilate. Arzneim. Forsch. 47: 1116-1124.
    • (1997) Arzneim. Forsch. , vol.47 , pp. 1116-1124
    • Kato, M.1    Nishida, A.2    Aga, Y.3    Kita, J.4    Kudo, Y.5    Narita, H.6    Endo, T.7
  • 197
    • 0031595085 scopus 로고    scopus 로고
    • The intradermal effects of the H3 receptor agonist R α methylhistamine in human skin
    • Kavanagh GM, Sabroe RA, Greaves MW and Archer CB (1998) The intradermal effects of the H3 receptor agonist R α methylhistamine in human skin. Br. J. Dermatol. 138: 622-626.
    • (1998) Br. J. Dermatol. , vol.138 , pp. 622-626
    • Kavanagh, G.M.1    Sabroe, R.A.2    Greaves, M.W.3    Archer, C.B.4
  • 198
    • 0038346446 scopus 로고    scopus 로고
    • Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic der-matitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study
    • Kawashima M, Tango T, Noguchi T, Inagi M, Nakagawa H and Harada S (2003) Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic der-matitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study. Br. J. Dermatol. 148: 1212-1221.
    • (2003) Br. J. Dermatol. , vol.148 , pp. 1212-1221
    • Kawashima, M.1    Tango, T.2    Noguchi, T.3    Inagi, M.4    Nakagawa, H.5    Harada, S.6
  • 199
    • 14444276731 scopus 로고    scopus 로고
    • Initial and steady-state effects of diphenhydramine and loratadine on sedation, cognition, mood, and psychomotor performance
    • Kay GG, Berman B, Mockoviak SH, Morris CE, Reeves D, Starbuck V, Sukenik E and Harris AG (1997) Initial and steady-state effects of diphenhydramine and loratadine on sedation, cognition, mood, and psychomotor performance. Arch. Intern. Med. 157: 2350-2356.
    • (1997) Arch. Intern. Med. , vol.157 , pp. 2350-2356
    • Kay, G.G.1    Berman, B.2    Mockoviak, S.H.3    Morris, C.E.4    Reeves, D.5    Starbuck, V.6    Sukenik, E.7    Harris, A.G.8
  • 200
    • 0032784403 scopus 로고    scopus 로고
    • Loratadine: A non-sedating antihistamine. Review of its effects on cognition, psychomotor performance, mood and sedation
    • Kay GG and Harris AG (1999) Loratadine: A non-sedating antihistamine. Review of its effects on cognition, psychomotor performance, mood and sedation. Clin. Exp. Allergy 29 Suppl 3:147-150.
    • (1999) Clin. Exp. Allergy , vol.29 , pp. 147-150
    • Kay, G.G.1    Harris, A.G.2
  • 201
    • 54049114310 scopus 로고    scopus 로고
    • Chronic urticaria: Diagnosis and management
    • Khan DA (2008) Chronic urticaria: Diagnosis and management. Allergy Asthma Proc. 29: 439-446.
    • (2008) Allergy Asthma Proc. , vol.29 , pp. 439-446
    • Khan, D.A.1
  • 202
    • 33748293049 scopus 로고    scopus 로고
    • Rifampin is safe for treatment of pruritus due to chronic cholestasis: A meta-analysis of prospective randomized-controlled trials
    • Khurana S and Singh P (2006) Rifampin is safe for treatment of pruritus due to chronic cholestasis: A meta-analysis of prospective randomized-controlled trials. Liver Int. 26: 943-948.
    • (2006) Liver Int. , vol.26 , pp. 943-948
    • Khurana, S.1    Singh, P.2
  • 204
    • 0020529517 scopus 로고
    • Inhibition of histamine-induced nasal symptoms by the H1 antihistamine chlorpheniramine maleate: Demonstration of topical effect
    • Kirkegaard J, Secher C, Borum P and Mygind N (1983) Inhibition of histamine-induced nasal symptoms by the H1 antihistamine chlorpheniramine maleate: Demonstration of topical effect. Br. J. Dis. Chest 77: 113-122.
    • (1983) Br. J. Dis. Chest , vol.77 , pp. 113-122
    • Kirkegaard, J.1    Secher, C.2    Borum, P.3    Mygind, N.4
  • 205
    • 0020122151 scopus 로고
    • Effect of the H1 antihistamine chlorpheniramine maleate on histamine-induced symptoms in the human conjunctiva. Indirect evidence for nervous H1 receptors
    • Kirkegaard J, Secher C and Mygind N (1982) Effect of the H1 antihistamine chlorpheniramine maleate on histamine-induced symptoms in the human conjunctiva. Indirect evidence for nervous H1 receptors. Allergy 37: 203-208.
    • (1982) Allergy , vol.37 , pp. 203-208
    • Kirkegaard, J.1    Secher, C.2    Mygind, N.3
  • 206
    • 0032801364 scopus 로고    scopus 로고
    • An evidence-based review of the efficacy of antihistamines in relieving pruritus in atopic dermatitis
    • Klein PA and Clark RAF (1999) An evidence-based review of the efficacy of antihistamines in relieving pruritus in atopic dermatitis. Arch. Dermatol. 135: 1522-1525.
    • (1999) Arch. Dermatol. , vol.135 , pp. 1522-1525
    • Klein, P.A.1    Clark, R.A.F.2
  • 208
    • 58249126793 scopus 로고    scopus 로고
    • Implications of the binding of tamoxi-fen to the coactivator recognition site of the estrogen receptor
    • Kojetin DJ, Burris TP, Jensen EV and Khan SA (2008) Implications of the binding of tamoxi-fen to the coactivator recognition site of the estrogen receptor. Endocr.-Relat. Cancer 15: 851-870.
    • (2008) Endocr.-Relat. Cancer , vol.15 , pp. 851-870
    • Kojetin, D.J.1    Burris, T.P.2    Jensen, E.V.3    Khan, S.A.4
  • 209
    • 9744281159 scopus 로고    scopus 로고
    • Chronic urticaria: Etiology, management and current and future treatment options
    • Kozel MMA and Sabroe RA (2004) Chronic urticaria: Etiology, management and current and future treatment options. Drugs 64: 2515-2536.
    • (2004) Drugs , vol.64 , pp. 2515-2536
    • Kozel, M.M.A.1    Sabroe, R.A.2
  • 211
    • 0033999939 scopus 로고    scopus 로고
    • Preclinical pharma-cology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist: Receptor selectivity, antihistaminic activity, and antiallergenic effects
    • Kreutner W, Hey JA, Anthes J, Barnett A, Young S and Tozzi S (2000) Preclinical pharma-cology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist: Receptor selectivity, antihistaminic activity, and antiallergenic effects. Arzneim. Forsch. 50: 345-352.
    • (2000) Arzneim. Forsch. , vol.50 , pp. 345-352
    • Kreutner, W.1    Hey, J.A.2    Anthes, J.3    Barnett, A.4    Young, S.5    Tozzi, S.6
  • 213
    • 0030701857 scopus 로고    scopus 로고
    • Increased interstitial histamine concentration in the psoriatic plaque
    • Krogstad AL, Lonnroth P, Larson G and Wallin BG (1997) Increased interstitial histamine concentration in the psoriatic plaque. J. Invest. Dermatol. 109: 632-635.
    • (1997) J. Invest. Dermatol. , vol.109 , pp. 632-635
    • Krogstad, A.L.1    Lonnroth, P.2    Larson, G.3    Wallin, B.G.4
  • 214
    • 81555208935 scopus 로고    scopus 로고
    • Several down, a few to go: Histamine H3 receptor ligands making the final push towards the market?
    • Kuhne S, Wijtmans M, Lim HD, Leurs R and de Esch IJP (2011) Several down, a few to go: Histamine H3 receptor ligands making the final push towards the market? Expert Opin. Invest. Drugs 20: 1629-1648.
    • (2011) Expert Opin. Invest. Drugs , vol.20 , pp. 1629-1648
    • Kuhne, S.1    Wijtmans, M.2    Lim, H.D.3    Leurs, R.4    de Esch, I.J.P.5
  • 215
    • 68349152746 scopus 로고    scopus 로고
    • Efficacy and safety of bilastine 20 mg compared with cetirizine 10 mg and placebo for the symptomatic treatment of seasonal aller-gic rhinitis: A randomized, double-blind, parallel-group study
    • Kuna P, Bachert C, Nowacki Z, van Cauwenberge P, Agache I, Fouquert L, Roger A, Sologuren A and Valiente R (2009) Efficacy and safety of bilastine 20 mg compared with cetirizine 10 mg and placebo for the symptomatic treatment of seasonal aller-gic rhinitis: A randomized, double-blind, parallel-group study. Clin. Exp. Allergy 39: 1338-1347.
    • (2009) Clin. Exp. Allergy , vol.39 , pp. 1338-1347
    • Kuna, P.1    Bachert, C.2    Nowacki, Z.3    van Cauwenberge, P.4    Agache, I.5    Fouquert, L.6    Roger, A.7    Sologuren, A.8    Valiente, R.9
  • 216
    • 38349154409 scopus 로고    scopus 로고
    • Ranitidine (150 mg daily) inhibits wheal, flare, and itching reactions in skin-prick tests
    • Kupczyk M, Kuprys I, Bochenska-Marciniak M, Gorski P and Kuna P (2007) Ranitidine (150 mg daily) inhibits wheal, flare, and itching reactions in skin-prick tests. Allergy Asthma Proc. 28: 711-715.
    • (2007) Allergy Asthma Proc. , vol.28 , pp. 711-715
    • Kupczyk, M.1    Kuprys, I.2    Bochenska-Marciniak, M.3    Gorski, P.4    Kuna, P.5
  • 217
    • 4344675185 scopus 로고    scopus 로고
    • Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexof-enadine
    • LaForce CF, Corren J, Wheeler WJ and Berger WE (2004) Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexof-enadine. Ann. Allergy Asthma Immunol. 93: 154-159.
    • (2004) Ann. Allergy Asthma Immunol. , vol.93 , pp. 154-159
    • LaForce, C.F.1    Corren, J.2    Wheeler, W.J.3    Berger, W.E.4
  • 218
    • 0027364939 scopus 로고
    • Initiation of the effects of acrivastine and cetirizine on histamine-induced wheals and itch in human skin
    • Lahti A and Haapaniemi T (1993) Initiation of the effects of acrivastine and cetirizine on histamine-induced wheals and itch in human skin. Acta Derm. Venereol. 73: 350-351.
    • (1993) Acta Derm. Venereol. , vol.73 , pp. 350-351
    • Lahti, A.1    Haapaniemi, T.2
  • 219
    • 80052997960 scopus 로고    scopus 로고
    • Mouse models of acute, chemical itch and pain in humans
    • LaMotte RH, Shimada SG and Sikand P (2011) Mouse models of acute, chemical itch and pain in humans. Exp. Dermatol. 20: 778-782.
    • (2011) Exp. Dermatol. , vol.20 , pp. 778-782
    • LaMotte, R.H.1    Shimada, S.G.2    Sikand, P.3
  • 220
  • 221
    • 33846466097 scopus 로고    scopus 로고
    • Itch and moti-vation to scratch: An investigation of the central and peripheral correlates of allergen- and histamine-induced itch in humans
    • Leknes SG, Bantick S, Willis CM, Wilkinson JD, Wise RG and Tracey I (2007) Itch and moti-vation to scratch: An investigation of the central and peripheral correlates of allergen- and histamine-induced itch in humans. J. Neurophysiol. 97: 415-422.
    • (2007) J. Neurophysiol. , vol.97 , pp. 415-422
    • Leknes, S.G.1    Bantick, S.2    Willis, C.M.3    Wilkinson, J.D.4    Wise, R.G.5    Tracey, I.6
  • 222
    • 80052072669 scopus 로고    scopus 로고
    • Histamine H4 receptors in normal conjunctiva and in vernal keratoconjunctivitis
    • Leonardi A, Di SA, Vicari C, Motterle L and Brun P (2011) Histamine H4 receptors in normal conjunctiva and in vernal keratoconjunctivitis. Allergy 66: 1360-1366.
    • (2011) Allergy , vol.66 , pp. 1360-1366
    • Leonardi, A.1    Di, S.A.2    Vicari, C.3    Motterle, L.4    Brun, P.5
  • 223
    • 0028246623 scopus 로고
    • Pharmacological characterization of the human histamine H2 receptor stably expressed in Chinese hamster ovary cells
    • Leurs R, Smit MJ, Menge WM and Timmerman H (1994a) Pharmacological characterization of the human histamine H2 receptor stably expressed in Chinese hamster ovary cells. Br. J. Pharmacol. 112: 847-854.
    • (1994) Br. J. Pharmacol. , vol.112 , pp. 847-854
    • Leurs, R.1    Smit, M.J.2    Menge, W.M.3    Timmerman, H.4
  • 224
    • 0028227786 scopus 로고
    • Site-directed mutagen-esis of the histamine H1-receptor reveals a selective interaction of asparagine207 with subclasses of H1-receptor agonists
    • Leurs R, Smit MJ, Tensen CP, Ter Laak AM and Timmerman H (1994b) Site-directed mutagen-esis of the histamine H1-receptor reveals a selective interaction of asparagine207 with subclasses of H1-receptor agonists. Biochem. Biophys. Res. Commun. 201: 295-301.
    • (1994) Biochem. Biophys. Res. Commun. , vol.201 , pp. 295-301
    • Leurs, R.1    Smit, M.J.2    Tensen, C.P.3    Ter Laak, A.M.4    Timmerman, H.5
  • 225
    • 0028880367 scopus 로고
    • Evaluation of the receptor selectivity of the H3 receptor antagonists, iodophenpropit and thioperamide: An interaction with the 5-HT3 receptor revealed
    • Leurs R, Tulp MTM, Menge WMBP, Adolfs MJP, Zuiderveld OP and Timmerman H (1995) Evaluation of the receptor selectivity of the H3 receptor antagonists, iodophenpropit and thioperamide: An interaction with the 5-HT3 receptor revealed. Br. J. Pharmacol. 116: 2315-2321.
    • (1995) Br. J. Pharmacol. , vol.116 , pp. 2315-2321
    • Leurs, R.1    Tulp, M.T.M.2    Menge, W.M.B.P.3    Adolfs, M.J.P.4    Zuiderveld, O.P.5    Timmerman, H.6
  • 226
    • 0021836682 scopus 로고
    • Peripheral antihistamine and central seda-tive effects of three H1-receptor antagonists
    • Levander S, Haegermark O and Staahle M (1985) Peripheral antihistamine and central seda-tive effects of three H1-receptor antagonists. Eur. J. Clin. Pharmacol. 28: 523-529.
    • (1985) Eur. J. Clin. Pharmacol. , vol.28 , pp. 523-529
    • Levander, S.1    Haegermark, O.2    Staahle, M.3
  • 227
    • 0025986690 scopus 로고
    • Peripheral antihistamine and central sedative effects of single and continuous oral doses of cetirizine and hydroxy-zine
    • Levander S, Staahle-Baeckdahl M and Haegermark O (1991) Peripheral antihistamine and central sedative effects of single and continuous oral doses of cetirizine and hydroxy-zine. Eur. J. Clin. Pharmacol. 41: 435-439.
    • (1991) Eur. J. Clin. Pharmacol. , vol.41 , pp. 435-439
    • Levander, S.1    Staahle-Baeckdahl, M.2    Haegermark, O.3
  • 229
    • 0003672250 scopus 로고
    • New York: Macmillan
    • Lewis T (1942) Pain. New York: Macmillan.
    • (1942) Pain
    • Lewis, T.1
  • 230
    • 33845904178 scopus 로고    scopus 로고
    • BF2.649 [1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine, hydro-chloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 recep-tor: Preclinical pharmacology
    • Ligneau X, Perrin D, Landais L, Camelin JC, Calmels TP, Berrebi-Bertrand I, Lecomte JM et al. (2007) BF2.649 [1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine, hydro-chloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 recep-tor: Preclinical pharmacology. J. Pharmacol. Exp. Ther. 320: 365-375.
    • (2007) J. Pharmacol. Exp. Ther. , vol.320 , pp. 365-375
    • Ligneau, X.1    Perrin, D.2    Landais, L.3    Camelin, J.C.4    Calmels, T.P.5    Berrebi-Bertrand, I.6    Lecomte, J.M.7
  • 231
    • 23944433719 scopus 로고    scopus 로고
    • Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: Identification of 4-methylhistamine as the first potent and selective H4 receptor agonist
    • Lim HD, van Rijn RM, Ling P, Bakker RA, Thurmond RL and Leurs R (2005) Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: Identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. J. Pharmacol. Exp. Ther. 314: 1310-1321.
    • (2005) J. Pharmacol. Exp. Ther. , vol.314 , pp. 1310-1321
    • Lim, H.D.1    van Rijn, R.M.2    Ling, P.3    Bakker, R.A.4    Thurmond, R.L.5    Leurs, R.6
  • 233
    • 0001486966 scopus 로고
    • Experimental skin pain induced by injection of water-soluble substances in humans
    • Lindahl O (1961) Experimental skin pain induced by injection of water-soluble substances in humans. Acta Physiol. Scand. 51:90 pp.
    • (1961) Acta Physiol. Scand. , vol.51 , pp. 90
    • Lindahl, O.1
  • 234
  • 237
    • 0034802259 scopus 로고    scopus 로고
    • Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation
    • Liu C, Wilson SJ, Kuei C and Lovenberg TW (2001b) Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation. J. Pharmacol. Exp. Ther. 299: 121-130.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 121-130
    • Liu, C.1    Wilson, S.J.2    Kuei, C.3    Lovenberg, T.W.4
  • 238
    • 82255175691 scopus 로고    scopus 로고
    • A double-masked study to compare the efficacy and safety of topical cromolyn for the treatment of allergic conjunctivitis
    • Liu YL, Hu FR, Wang IJ, Chen WL and Hou YC (2011) A double-masked study to compare the efficacy and safety of topical cromolyn for the treatment of allergic conjunctivitis. J. Formos Med. Assoc. 110: 690-694.
    • (2011) J. Formos Med. Assoc. , vol.110 , pp. 690-694
    • Liu, Y.L.1    Hu, F.R.2    Wang, I.J.3    Chen, W.L.4    Hou, Y.C.5
  • 239
    • 84898727421 scopus 로고
    • Alleviation of anaphylactic shock in guinea pigs with syn-thetic benzohydryl alkamine ethers
    • Loew ER and Kaiser ME (1945) Alleviation of anaphylactic shock in guinea pigs with syn-thetic benzohydryl alkamine ethers. Proc. Soc. Exp. Biol. Med. 58: 235-237.
    • (1945) Proc. Soc. Exp. Biol. Med. , vol.58 , pp. 235-237
    • Loew, E.R.1    Kaiser, M.E.2
  • 240
    • 84889479731 scopus 로고
    • Synthetic benzohydryl alkamine ethers effective in preventing fatal experimental asthma in guinea pigs exposed to atomized histamine
    • Loew ER, Kaiser ME and Moore V (1945) Synthetic benzohydryl alkamine ethers effective in preventing fatal experimental asthma in guinea pigs exposed to atomized histamine. J. Pharmacol. 83: 120-129.
    • (1945) J. Pharmacol. , vol.83 , pp. 120-129
    • Loew, E.R.1    Kaiser, M.E.2    Moore, V.3
  • 242
    • 34548703579 scopus 로고    scopus 로고
    • Efficacy and safety of azelastine nasal spray at a dose of 1 spray per nostril twice daily
    • Lumry W, Prenner B, Corren J and Wheeler W (2007) Efficacy and safety of azelastine nasal spray at a dose of 1 spray per nostril twice daily. Ann. Allergy Asthma Immunol. 99: 267-272.
    • (2007) Ann. Allergy Asthma Immunol. , vol.99 , pp. 267-272
    • Lumry, W.1    Prenner, B.2    Corren, J.3    Wheeler, W.4
  • 243
  • 245
    • 34347262074 scopus 로고    scopus 로고
    • Efficacy and comfort of olopatadine 0.2% versus epinastine 0.05% ophthalmic solution for treating itching and redness induced by conjunctival allergen challenge
    • Mah FS, Rosenwasser LJ, Townsend WD, Greiner JV and Bensch G (2007) Efficacy and comfort of olopatadine 0.2% versus epinastine 0.05% ophthalmic solution for treating itching and redness induced by conjunctival allergen challenge. Curr. Med. Res. Opin. 23: 1445-1452.
    • (2007) Curr. Med. Res. Opin. , vol.23 , pp. 1445-1452
    • Mah, F.S.1    Rosenwasser, L.J.2    Townsend, W.D.3    Greiner, J.V.4    Bensch, G.5
  • 246
    • 62149115189 scopus 로고    scopus 로고
    • Uraemic pruritus: Clinical characteristics, patho-physiology and treatment
    • Manenti L, Tansinda P and Vaglio A (2009) Uraemic pruritus: Clinical characteristics, patho-physiology and treatment. Drugs 69: 251-263.
    • (2009) Drugs , vol.69 , pp. 251-263
    • Manenti, L.1    Tansinda, P.2    Vaglio, A.3
  • 248
    • 0017755541 scopus 로고
    • Vascular reactions to histamine and compound 48/80 in human skin: Suppression by a histamine H2-receptor blocking agent
    • Marks R and Greaves MW (1977) Vascular reactions to histamine and compound 48/80 in human skin: Suppression by a histamine H2-receptor blocking agent. Br. J. Clin. Pharmacol. 4: 367-369.
    • (1977) Br. J. Clin. Pharmacol. , vol.4 , pp. 367-369
    • Marks, R.1    Greaves, M.W.2
  • 249
    • 0025719927 scopus 로고
    • Histamine-induced increases in cyclic AMP levels in bovine adrenal medullary cells
    • Marley PD, Thomson KA, Jachno K and Johnston MJ (1991) Histamine-induced increases in cyclic AMP levels in bovine adrenal medullary cells. Br. J. Pharmacol. 104: 839-846.
    • (1991) Br. J. Pharmacol. , vol.104 , pp. 839-846
    • Marley, P.D.1    Thomson, K.A.2    Jachno, K.3    Johnston, M.J.4
  • 250
    • 84865316898 scopus 로고    scopus 로고
    • Advantages of histamine H4 receptor antagonist usage with H1 receptor antagonist for the treatment of murine allergic contact dermatitis
    • Matsushita A, Seike M, Okawa H, Kadawaki Y and Ohtsu H (2012) Advantages of histamine H4 receptor antagonist usage with H1 receptor antagonist for the treatment of murine allergic contact dermatitis. Exp. Dermatol. 21: 714-715.
    • (2012) Exp. Dermatol. , vol.21 , pp. 714-715
    • Matsushita, A.1    Seike, M.2    Okawa, H.3    Kadawaki, Y.4    Ohtsu, H.5
  • 252
    • 84872444223 scopus 로고
    • Clinical observations on the use of benadryl; a new anti-histamine substance
    • McElin TW and Horton BT (1945) Clinical observations on the use of benadryl; a new anti-histamine substance. Proc. Staff Meet. Mayo Clin. 20: 417-429.
    • (1945) Proc. Staff Meet. Mayo Clin. , vol.20 , pp. 417-429
    • McElin, T.W.1    Horton, B.T.2
  • 253
    • 33745714300 scopus 로고    scopus 로고
    • Characterizing impaired functional alertness from diphenhydramine in the elderly with performance and neurophysiologic measures
    • McEvoy LK, Smith ME, Fordyce M and Gevins A (2006) Characterizing impaired functional alertness from diphenhydramine in the elderly with performance and neurophysiologic measures. Sleep 29: 957-966.
    • (2006) Sleep , vol.29 , pp. 957-966
    • McEvoy, L.K.1    Smith, M.E.2    Fordyce, M.3    Gevins, A.4
  • 254
    • 84956579083 scopus 로고
    • Some pharmacological and clinical experiences with dimethylaminoethyl benzhydryl ether hydrochloride (benadryl)
    • McGavack TH, Elias H and Boyd LJ (1946) Some pharmacological and clinical experiences with dimethylaminoethyl benzhydryl ether hydrochloride (benadryl). Bull. N. Y. Acad. Med. 22:481.
    • (1946) Bull. N. Y. Acad. Med. , vol.22 , pp. 481
    • McGavack, T.H.1    Elias, H.2    Boyd, L.J.3
  • 255
    • 0037392389 scopus 로고    scopus 로고
    • Review article: Pruritus in cholestatic and other liver diseases
    • Mela M, Mancuso A and Burroughs AK (2003) Review article: Pruritus in cholestatic and other liver diseases. Aliment. Pharmacol. Ther. 17: 857-870.
    • (2003) Aliment. Pharmacol. Ther. , vol.17 , pp. 857-870
    • Mela, M.1    Mancuso, A.2    Burroughs, A.K.3
  • 257
    • 84864753109 scopus 로고    scopus 로고
    • MP29-02 (a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate) in the treatment of seasonal allergic rhinitis: A randomized, double-blind, placebo-controlled trial of efficacy and safety
    • Meltzer EO, Laforce C, Ratner P, Price D, Ginsberg D and Carr W (2012) MP29-02 (a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate) in the treatment of seasonal allergic rhinitis: A randomized, double-blind, placebo-controlled trial of efficacy and safety. Allergy Asthma Proc. 33: 324-332.
    • (2012) Allergy Asthma Proc. , vol.33 , pp. 324-332
    • Meltzer, E.O.1    Laforce, C.2    Ratner, P.3    Price, D.4    Ginsberg, D.5    Carr, W.6
  • 259
    • 76349095566 scopus 로고    scopus 로고
    • Pruritus in cutaneous T-cell lymphomas: Frequent, often severe and difficult to treat
    • Meyer N, Paul C and Misery L (2010) Pruritus in cutaneous T-cell lymphomas: Frequent, often severe and difficult to treat. Acta Derm. Venereol. 90: 12-17.
    • (2010) Acta Derm. Venereol. , vol.90 , pp. 12-17
    • Meyer, N.1    Paul, C.2    Misery, L.3
  • 260
    • 0022366123 scopus 로고
    • The effect of ranitidine, alone and in combination with clemastine, on allergen-induced cutaneous wheal-and-flare reac-tions in human skin
    • Meyrick-Thomas RH, Browne PD and Kirby JDT (1985a) The effect of ranitidine, alone and in combination with clemastine, on allergen-induced cutaneous wheal-and-flare reac-tions in human skin. J. Allergy Clin. Immunol. 76: 864-869.
    • (1985) J. Allergy Clin. Immunol. , vol.76 , pp. 864-869
    • Meyrick-Thomas, R.H.1    Browne, P.D.2    Kirby, J.D.T.3
  • 261
    • 0022356411 scopus 로고
    • The influence of ranitidine, alone and in combination with clemastine, on histamine-mediated cutaneous weal and flare reactions in human skin
    • Meyrick-Thomas RH, Browne PD and Kirby JDT (1985b) The influence of ranitidine, alone and in combination with clemastine, on histamine-mediated cutaneous weal and flare reactions in human skin. Br. J. Clin. Pharmacol. 20: 377-382.
    • (1985) Br. J. Clin. Pharmacol. , vol.20 , pp. 377-382
    • Meyrick-Thomas, R.H.1    Browne, P.D.2    Kirby, J.D.T.3
  • 263
    • 0015840923 scopus 로고
    • Urticaria induced by preservatives and dye additives in food and drugs
    • Michaelsson G and Juhlin L (1973) Urticaria induced by preservatives and dye additives in food and drugs. Brit. J. Dermatol. 88: 525-532.
    • (1973) Brit. J. Dermatol. , vol.88 , pp. 525-532
    • Michaelsson, G.1    Juhlin, L.2
  • 265
    • 0141515633 scopus 로고    scopus 로고
    • Imaging of cen-tral itch modulation in the human brain using positron emission tomography
    • Mochizuki H, Tashiro M, Kano M, Sakurada Y, Itoh M and Yanai K (2003) Imaging of cen-tral itch modulation in the human brain using positron emission tomography. Pain 105: 339-346.
    • (2003) Pain , vol.105 , pp. 339-346
    • Mochizuki, H.1    Tashiro, M.2    Kano, M.3    Sakurada, Y.4    Itoh, M.5    Yanai, K.6
  • 268
    • 0037380546 scopus 로고    scopus 로고
    • Efficacy and safety of desloratadine 5 mg once daily in the treatment of chronic idiopathic urticaria: A double-blind, randomized, placebo-controlled trial
    • Monroe E, Finn A, Patel P, Guerrero R, Ratner P and Bernstein D (2003) Efficacy and safety of desloratadine 5 mg once daily in the treatment of chronic idiopathic urticaria: A double-blind, randomized, placebo-controlled trial. J. Am. Acad. Dermatol. 48: 535-541.
    • (2003) J. Am. Acad. Dermatol. , vol.48 , pp. 535-541
    • Monroe, E.1    Finn, A.2    Patel, P.3    Guerrero, R.4    Ratner, P.5    Bernstein, D.6
  • 269
    • 0026507828 scopus 로고
    • Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria and atopic dermatitis
    • Monroe EW (1992) Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria and atopic dermatitis. Clin. Ther. 14: 17-21.
    • (1992) Clin. Ther. , vol.14 , pp. 17-21
    • Monroe, E.W.1
  • 270
    • 0027179068 scopus 로고
    • Involvement of histamine in the control of the waking state
    • Monti JM (1993) Involvement of histamine in the control of the waking state. Life Sci. 53: 1331-1338.
    • (1993) Life Sci. , vol.53 , pp. 1331-1338
    • Monti, J.M.1
  • 271
    • 14644396602 scopus 로고    scopus 로고
    • Double-blind, crossover comparison of olopatadine and cetirizine versus placebo: Suppressive effects on skin response to histamine ionto-phoresis
    • Morita E, Matsuo H and Zhang Y (2005) Double-blind, crossover comparison of olopatadine and cetirizine versus placebo: Suppressive effects on skin response to histamine ionto-phoresis. J. Dermatol. 32: 58-61.
    • (2005) J. Dermatol. , vol.32 , pp. 58-61
    • Morita, E.1    Matsuo, H.2    Zhang, Y.3
  • 274
    • 0036878197 scopus 로고    scopus 로고
    • Comprehensive evaluation of cetirizine in the management of seasonal allergic rhini-tis: Impact on symptoms, quality of life, productivity, and activity impairment
    • Murray JJ, Nathan RA, Bronsky EA, Olufade AO, Chapman D and Kramer B (2002) Comprehensive evaluation of cetirizine in the management of seasonal allergic rhini-tis: Impact on symptoms, quality of life, productivity, and activity impairment. Allergy Asthma Proc. 23: 391-398.
    • (2002) Allergy Asthma Proc. , vol.23 , pp. 391-398
    • Murray, J.J.1    Nathan, R.A.2    Bronsky, E.A.3    Olufade, A.O.4    Chapman, D.5    Kramer, B.6
  • 275
    • 0020315708 scopus 로고
    • Mediators of nasal allergy
    • Mygind N (1982) Mediators of nasal allergy. J. Allergy Clin. Immunol. 70: 149-159.
    • (1982) J. Allergy Clin. Immunol. , vol.70 , pp. 149-159
    • Mygind, N.1
  • 277
    • 0025784942 scopus 로고
    • The nasal allergic reaction: Observations on the role of histamine
    • Naclerio RM and Togias AG (1991) The nasal allergic reaction: Observations on the role of histamine. Clin. Exp. Allergy 21 Suppl 2:13-19.
    • (1991) Clin. Exp. Allergy , vol.21 , pp. 13-19
    • Naclerio, R.M.1    Togias, A.G.2
  • 279
    • 84856561777 scopus 로고    scopus 로고
    • Alcaftadine: A topical antihistamine for use in allergic con-junctivitis
    • Namdar R and Valdez C (2011) Alcaftadine: A topical antihistamine for use in allergic con-junctivitis. Drugs Today 47: 883-890.
    • (2011) Drugs Today , vol.47 , pp. 883-890
    • Namdar, R.1    Valdez, C.2
  • 281
    • 33644914178 scopus 로고    scopus 로고
    • Levocetirizine in the treatment of chronic idiopathic urticaria: A randomized, double-blind, placebo-controlled study
    • Nettis E, Colanardi MC, Barra L, Ferrannini A, Vacca A and Tursi A (2006) Levocetirizine in the treatment of chronic idiopathic urticaria: A randomized, double-blind, placebo-controlled study. Br. J. Dermatol. 154: 533-538.
    • (2006) Br. J. Dermatol. , vol.154 , pp. 533-538
    • Nettis, E.1    Colanardi, M.C.2    Barra, L.3    Ferrannini, A.4    Vacca, A.5    Tursi, A.6
  • 283
    • 0037337119 scopus 로고    scopus 로고
    • The health-related quality of life effects of once-daily cetirizine HCl in patients with seasonal allergic rhinitis: A randomized double-blind, placebo-controlled trial
    • Noonan MJ, Raphael GD, Nayak A, Greos L, Olufade AO, Leidy NK, Champan D and Kramer B (2003) The health-related quality of life effects of once-daily cetirizine HCl in patients with seasonal allergic rhinitis: A randomized double-blind, placebo-controlled trial. Clin. Exp. Allergy 33: 351-358.
    • (2003) Clin. Exp. Allergy , vol.33 , pp. 351-358
    • Noonan, M.J.1    Raphael, G.D.2    Nayak, A.3    Greos, L.4    Olufade, A.O.5    Leidy, N.K.6    Champan, D.7    Kramer, B.8
  • 284
  • 285
    • 29144478251 scopus 로고    scopus 로고
    • Antihistamines and their role as antipruritics
    • O’Donoghue M and Tharp MD (2005) Antihistamines and their role as antipruritics. Dermatol. Ther. 18: 333-340.
    • (2005) Dermatol. Ther. , vol.18 , pp. 333-340
    • O’Donoghue, M.1    Tharp, M.D.2
  • 288
    • 0034711258 scopus 로고    scopus 로고
    • Molecular cloning and char-acterization of a novel type of histamine receptor preferentially expressed in leukocytes
    • Oda T, Morikawa N, Saito Y, Masuho Y and Matsumoto S (2000) Molecular cloning and char-acterization of a novel type of histamine receptor preferentially expressed in leukocytes. J. Biol. Chem. 275: 36781-36786.
    • (2000) J. Biol. Chem. , vol.275 , pp. 36781-36786
    • Oda, T.1    Morikawa, N.2    Saito, Y.3    Masuho, Y.4    Matsumoto, S.5
  • 289
    • 0024244921 scopus 로고
    • Double-blind comparison of loratadine (SCH 29851), astemizole, and placebo in hay fever with special regard to onset of action
    • Oei HD (1988) Double-blind comparison of loratadine (SCH 29851), astemizole, and placebo in hay fever with special regard to onset of action. Ann. Allergy 61: 436-439.
    • (1988) Ann. Allergy , vol.61 , pp. 436-439
    • Oei, H.D.1
  • 290
    • 84863845497 scopus 로고    scopus 로고
    • The antagonism of histamine H1 and H4 receptors amelio-rates chronic allergic dermatitis via anti-pruritic and anti-inflammatory effects in NC/Nga mice
    • Ohsawa Y and Hirasawa N (2012) The antagonism of histamine H1 and H4 receptors amelio-rates chronic allergic dermatitis via anti-pruritic and anti-inflammatory effects in NC/Nga mice. Allergy 67: 1014-1022.
    • (2012) Allergy , vol.67 , pp. 1014-1022
    • Ohsawa, Y.1    Hirasawa, N.2
  • 291
    • 66849093867 scopus 로고    scopus 로고
    • Histamine H1-receptor antagonists with immunomodulating activities: Potential use for modulating T helper type 1 (Th1)/Th2 cytokine imbalance and inflammatory responses in allergic diseases
    • Okamoto T, Iwata S, Ohnuma K, Dang NH and Morimoto C (2009) Histamine H1-receptor antagonists with immunomodulating activities: Potential use for modulating T helper type 1 (Th1)/Th2 cytokine imbalance and inflammatory responses in allergic diseases. Clin. Exp. Immunol. 157: 27-34.
    • (2009) Clin. Exp. Immunol. , vol.157 , pp. 27-34
    • Okamoto, T.1    Iwata, S.2    Ohnuma, K.3    Dang, N.H.4    Morimoto, C.5
  • 293
    • 33746114247 scopus 로고    scopus 로고
    • Presence and characterization of prostaglandin D2-related molecules in nasal mucosa of patients with allergic rhinitis
    • Okano M, Fujiwara T, Sugata Y, Gotoh D, Masaoka Y, Sogo M, Tanimoto W et al. (2006) Presence and characterization of prostaglandin D2-related molecules in nasal mucosa of patients with allergic rhinitis. Am. J. Rhinol. 20: 342-348.
    • (2006) Am. J. Rhinol. , vol.20 , pp. 342-348
    • Okano, M.1    Fujiwara, T.2    Sugata, Y.3    Gotoh, D.4    Masaoka, Y.5    Sogo, M.6    Tanimoto, W.7
  • 294
    • 11344288457 scopus 로고    scopus 로고
    • Allergic conjunctivitis: Update on pathophysiology and pros-pects for future treatment
    • Ono SJ and Abelson MB (2005) Allergic conjunctivitis: Update on pathophysiology and pros-pects for future treatment. J. Allergy Clin. Immunol. 115: 118-122.
    • (2005) J. Allergy Clin. Immunol. , vol.115 , pp. 118-122
    • Ono, S.J.1    Abelson, M.B.2
  • 295
    • 0036657063 scopus 로고    scopus 로고
    • Comparison of emedastine 0.05% or nedocromil sodium 2% eye drops and placebo in controlling local reactions in subjects with allergic conjunctivitis
    • Orfeo V, Vardaro A, Lena P, Mensitieri I, Tracey M and De Marco R (2002) Comparison of emedastine 0.05% or nedocromil sodium 2% eye drops and placebo in controlling local reactions in subjects with allergic conjunctivitis. Eur. J. Ophthalmol. 12: 262-266.
    • (2002) Eur. J. Ophthalmol. , vol.12 , pp. 262-266
    • Orfeo, V.1    Vardaro, A.2    Lena, P.3    Mensitieri, I.4    Tracey, M.5    De Marco, R.6
  • 296
    • 81255150140 scopus 로고    scopus 로고
    • Chronic urticaria: A comparison of management guidelines
    • Ortonne JP (2011) Chronic urticaria: A comparison of management guidelines. Expert Opin. Pharmacother. 12: 2683-2693.
    • (2011) Expert Opin. Pharmacother. , vol.12 , pp. 2683-2693
    • Ortonne, J.P.1
  • 297
    • 34247242642 scopus 로고    scopus 로고
    • Efficacy and safety of desloratadine in adults with chronic idiopathic urticaria: A randomized, double-blind, placebo-controlled, multicenter trial
    • Ortonne JP, Grob JJ, Auquier P and Dreyfus I (2007) Efficacy and safety of desloratadine in adults with chronic idiopathic urticaria: A randomized, double-blind, placebo-controlled, multicenter trial. Am. J. Clin. Dermatol. 8: 37-42.
    • (2007) Am. J. Clin. Dermatol. , vol.8 , pp. 37-42
    • Ortonne, J.P.1    Grob, J.J.2    Auquier, P.3    Dreyfus, I.4
  • 298
    • 84855170132 scopus 로고    scopus 로고
    • A tale of two itches. Common features and notable differences in brain activation evoked by cowhage and histamine induced itch
    • Papoiu ADP, Coghill RC, Kraft RA, Wang H and Yosipovitch G (2012) A tale of two itches. Common features and notable differences in brain activation evoked by cowhage and histamine induced itch. Neuroimage 59: 3611-3623.
    • (2012) Neuroimage , vol.59 , pp. 3611-3623
    • Papoiu, A.D.P.1    Coghill, R.C.2    Kraft, R.A.3    Wang, H.4    Yosipovitch, G.5
  • 299
    • 84908757807 scopus 로고
    • Les Modifications Aportees par un Antagoniste de L’histamine (2, 339 R.P.) a la Reaction Vasculaire Locale de la Peau
    • Parrot J-J (1942) Les Modifications Aportees par un Antagoniste de L’histamine (2, 339 R.P.) a la Reaction Vasculaire Locale de la Peau. C. R. Seances Soc. Biol. Ses Fil. 136: 715-716.
    • (1942) C. R. Seances Soc. Biol. Ses Fil. , vol.136 , pp. 715-716
    • Parrot, J.-J.1
  • 300
    • 33646418808 scopus 로고    scopus 로고
    • Frontiers in pruritus research: Scratching the brain for more effective itch therapy
    • Paus R, Schmelz M, Biro T and Steinhoff M (2006) Frontiers in pruritus research: Scratching the brain for more effective itch therapy. J. Clin. Invest. 116: 1174-1185.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1174-1185
    • Paus, R.1    Schmelz, M.2    Biro, T.3    Steinhoff, M.4
  • 301
    • 84857063512 scopus 로고    scopus 로고
    • Allergic contact dermatitis: Epidemiology, molecular mechanisms, in vitro methods and regu-latory aspects. Current knowledge assembled at an international workshop at BfR, Germany
    • Peiser M, Tralau T, Heidler J, Api AM, Arts JH, Basketter DA, English J et al. (2012) Allergic contact dermatitis: Epidemiology, molecular mechanisms, in vitro methods and regu-latory aspects. Current knowledge assembled at an international workshop at BfR, Germany. Cell. Mol. Life Sci. 69: 763-781.
    • (2012) Cell. Mol. Life Sci. , vol.69 , pp. 763-781
    • Peiser, M.1    Tralau, T.2    Heidler, J.3    Api, A.M.4    Arts, J.H.5    Basketter, D.A.6    English, J.7
  • 303
    • 0041324629 scopus 로고    scopus 로고
    • Levocetirizine is effective for symptom relief including nasal congestion in adolescent and adult (PAR) sensitized to house dust mites
    • Potter PC (2003) Levocetirizine is effective for symptom relief including nasal congestion in adolescent and adult (PAR) sensitized to house dust mites. Allergy 58: 893-899.
    • (2003) Allergy , vol.58 , pp. 893-899
    • Potter, P.C.1
  • 306
    • 34248598463 scopus 로고    scopus 로고
    • Mutations of Cys-17 and Ala-271 in the human histamine H2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity
    • Preuss H, Ghorai P, Kraus A, Dove S, Buschauer A and Seifert R (2007) Mutations of Cys-17 and Ala-271 in the human histamine H2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity. J. Pharmacol. Exp. Ther. 321: 975-982.
    • (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 975-982
    • Preuss, H.1    Ghorai, P.2    Kraus, A.3    Dove, S.4    Buschauer, A.5    Seifert, R.6
  • 308
    • 37849030732 scopus 로고    scopus 로고
    • Combination therapy with azelastine hydrochloride nasal spray and fluticasone propio-nate nasal spray in the treatment of patients with seasonal allergic rhinitis
    • Ratner PH, Hampel F, Van Bavel J, Amar NJ, Daftary P, Wheeler W and Sacks H (2008) Combination therapy with azelastine hydrochloride nasal spray and fluticasone propio-nate nasal spray in the treatment of patients with seasonal allergic rhinitis. Ann. Allergy Asthma Immunol. 100: 74-81.
    • (2008) Ann. Allergy Asthma Immunol. , vol.100 , pp. 74-81
    • Ratner, P.H.1    Hampel, F.2    Van Bavel, J.3    Amar, N.J.4    Daftary, P.5    Wheeler, W.6    Sacks, H.7
  • 310
    • 43749117724 scopus 로고    scopus 로고
    • Cowhage-evoked itch is mediated by a novel cysteine protease: A ligand of protease-activated receptors
    • Reddy VB, Iuga AO, Shimada SG, LaMotte RH and Lerner EA (2008) Cowhage-evoked itch is mediated by a novel cysteine protease: A ligand of protease-activated receptors. J. Neurosci. 28: 4331-4335.
    • (2008) J. Neurosci. , vol.28 , pp. 4331-4335
    • Reddy, V.B.1    Iuga, A.O.2    Shimada, S.G.3    LaMotte, R.H.4    Lerner, E.A.5
  • 313
    • 0017813718 scopus 로고
    • Responses of human skin blood vessels to synthetic histamine analogs
    • Robertson I and Greaves MW (1978) Responses of human skin blood vessels to synthetic histamine analogs. Br. J. Clin. Pharmacol. 5: 319-322.
    • (1978) Br. J. Clin. Pharmacol. , vol.5 , pp. 319-322
    • Robertson, I.1    Greaves, M.W.2
  • 315
    • 0000994059 scopus 로고
    • Histamine as the chemical mediator for cutaneous pain
    • Rosenthal SR and Minard D (1939) Histamine as the chemical mediator for cutaneous pain. J. Exp. Med. 70: 415-425.
    • (1939) J. Exp. Med. , vol.70 , pp. 415-425
    • Rosenthal, S.R.1    Minard, D.2
  • 318
    • 0000933860 scopus 로고
    • Physiology of itching
    • Rothman S (1941) Physiology of itching. Physiol. Rev. 21: 357-381.
    • (1941) Physiol. Rev. , vol.21 , pp. 357-381
    • Rothman, S.1
  • 319
    • 0034088058 scopus 로고    scopus 로고
    • Mast cell mediators other than histamine induce pruritus in atopic dermatitis patients. A dermal microdialy-sis study
    • Rukwied R, Lischetzki G, McGlone F, Heyer G and Schmelz M (2000) Mast cell mediators other than histamine induce pruritus in atopic dermatitis patients. A dermal microdialy-sis study. Br. J. Dermatol. 142: 1114-1120.
    • (2000) Br. J. Dermatol. , vol.142 , pp. 1114-1120
    • Rukwied, R.1    Lischetzki, G.2    McGlone, F.3    Heyer, G.4    Schmelz, M.5
  • 322
    • 0036116885 scopus 로고    scopus 로고
    • Effects of N-alpha-methyl-histamine on human H2 receptors expressed in CHO cells
    • Saitoh T, Fukushima Y, Otsuka H, Ishikawa M, Tamai M, Takahashi H, Mori H et al. (2002) Effects of N-alpha-methyl-histamine on human H2 receptors expressed in CHO cells. Gut 50: 786-789.
    • (2002) Gut , vol.50 , pp. 786-789
    • Saitoh, T.1    Fukushima, Y.2    Otsuka, H.3    Ishikawa, M.4    Tamai, M.5    Takahashi, H.6    Mori, H.7
  • 323
    • 0024347041 scopus 로고
    • A comparison of acrivastine versus hydroxyzine and placebo in the treatment of chronic idiopathic urticaria
    • Salo OP, Harvey SG, Calthrop JG and Gibson JR (1989) A comparison of acrivastine versus hydroxyzine and placebo in the treatment of chronic idiopathic urticaria. J. Int. Med. Res. 17 Suppl 2:18B-21B.
    • (1989) J. Int. Med. Res. , vol.17 , pp. 18B-21B
    • Salo, O.P.1    Harvey, S.G.2    Calthrop, J.G.3    Gibson, J.R.4
  • 325
    • 44349159558 scopus 로고    scopus 로고
    • Ketorolac tromethamine 0.4% as a treatment for allergic conjuctivitis
    • Schechter BA (2008) Ketorolac tromethamine 0.4% as a treatment for allergic conjuctivitis. Expert Opin. Drug Metab. Toxicol. 4: 507-511.
    • (2008) Expert Opin. Drug Metab. Toxicol. , vol.4 , pp. 507-511
    • Schechter, B.A.1
  • 326
    • 0035149068 scopus 로고    scopus 로고
    • A neural pathway for itch
    • Schmelz M (2001) A neural pathway for itch. Nat. Neurosci. 4: 9-10.
    • (2001) Nat. Neurosci. , vol.4 , pp. 9-10
    • Schmelz, M.1
  • 330
    • 48449092252 scopus 로고    scopus 로고
    • Significant differences in central imaging of histamine-induced itch between atopic dermatitis and healthy subjects
    • Schneider G, Staender S, Burgmer M, Driesch G, Heuft G and Weckesser M (2008) Significant differences in central imaging of histamine-induced itch between atopic dermatitis and healthy subjects. Eur. J. Pain 12: 834-841.
    • (2008) Eur. J. Pain , vol.12 , pp. 834-841
    • Schneider, G.1    Staender, S.2    Burgmer, M.3    Driesch, G.4    Heuft, G.5    Weckesser, M.6
  • 332
    • 0020000899 scopus 로고
    • Significance of H1 and H2 receptors in the human nose: Rationale for topical use of combined antihistamine preparations
    • Secher C, Kirkegaard J, Borum P, Maansson A, Osterhammel P and Mygind N (1982) Significance of H1 and H2 receptors in the human nose: Rationale for topical use of combined antihistamine preparations. J. Allergy Clin. Immunol. 70: 211-218.
    • (1982) J. Allergy Clin. Immunol. , vol.70 , pp. 211-218
    • Secher, C.1    Kirkegaard, J.2    Borum, P.3    Maansson, A.4    Osterhammel, P.5    Mygind, N.6
  • 334
    • 76249129682 scopus 로고    scopus 로고
    • Histamine H4 receptor antagonist ameliorates chronic allergic contact dermatitis induced by repeated challenge
    • Seike M, Furuya K, Omura M, Hamada-Watanabe K, Matsushita A and Ohtsu H (2010) Histamine H4 receptor antagonist ameliorates chronic allergic contact dermatitis induced by repeated challenge. Allergy 65: 319-326.
    • (2010) Allergy , vol.65 , pp. 319-326
    • Seike, M.1    Furuya, K.2    Omura, M.3    Hamada-Watanabe, K.4    Matsushita, A.5    Ohtsu, H.6
  • 335
    • 0033746828 scopus 로고    scopus 로고
    • Sedation and antihistamines: A review of inter-drug dif-ferences using proportional impairment ratios
    • Shamsi Z and Hindmarch I (2000) Sedation and antihistamines: A review of inter-drug dif-ferences using proportional impairment ratios. Human Psychopharmacol. 15:S3-S30.
    • (2000) Human Psychopharmacol. , vol.15 , pp. S3-S30
    • Shamsi, Z.1    Hindmarch, I.2
  • 336
    • 0029853560 scopus 로고    scopus 로고
    • Olopatadine (AL-4943A): Ligand binding and func-tional studies on a novel, long-acting, H1-selective histamine antagonist and antiallergic agent for use in allergic conjunctivitis
    • Sharif NA, Xu SX and Yanni JM (1996) Olopatadine (AL-4943A): ligand binding and func-tional studies on a novel, long-acting, H1-selective histamine antagonist and antiallergic agent for use in allergic conjunctivitis. J. Ocul. Pharmacol. Ther. 12: 401-407.
    • (1996) J. Ocul. Pharmacol. Ther. , vol.12 , pp. 401-407
    • Sharif, N.A.1    Xu, S.X.2    Yanni, J.M.3
  • 337
    • 0001481858 scopus 로고
    • Mucunain, the active pruritogenic proteinase of cowhage
    • Shelley WB and Arthur RP (1955) Mucunain, the active pruritogenic proteinase of cowhage. Science 122: 469-470.
    • (1955) Science , vol.122 , pp. 469-470
    • Shelley, W.B.1    Arthur, R.P.2
  • 338
    • 0013133242 scopus 로고
    • Relative effect of local anesthetics on experimental hista-mine pruritus in man
    • Shelley WB and Melton FM (1950) Relative effect of local anesthetics on experimental hista-mine pruritus in man. J. Invest. Dermatol. 15: 299-300.
    • (1950) J. Invest. Dermatol. , vol.15 , pp. 299-300
    • Shelley, W.B.1    Melton, F.M.2
  • 340
    • 53349177794 scopus 로고    scopus 로고
    • Behavioral differentiation between itch and pain in mouse
    • Shimada SG and LaMotte RH (2008) Behavioral differentiation between itch and pain in mouse. Pain 139: 681-687.
    • (2008) Pain , vol.139 , pp. 681-687
    • Shimada, S.G.1    LaMotte, R.H.2
  • 341
    • 84855440025 scopus 로고    scopus 로고
    • INCB38579, a novel and potent histamine H4 receptor small molecule antagonist with anti-inflammatorypain and anti-pruritic functions
    • Shin N, Covington M, Bian D, Zhuo J, Bowman K, Li Y, Soloviev M et al. (2012) INCB38579, a novel and potent histamine H4 receptor small molecule antagonist with anti-inflammatorypain and anti-pruritic functions. Eur. J. Pharmacol. 675: 47-56.
    • (2012) Eur. J. Pharmacol. , vol.675 , pp. 47-56
    • Shin, N.1    Covington, M.2    Bian, D.3    Zhuo, J.4    Bowman, K.5    Li, Y.6    Soloviev, M.7
  • 342
    • 61549112485 scopus 로고    scopus 로고
    • High-dose deslorata-dine decreases wheal volume and improves cold provocation thresholds compared with standard-dose treatment in patients with acquired cold urticaria: A randomized, placebo-controlled, crossover study
    • Siebenhaar F, Degener F, Zuberbier T, Martus P and Maurer M (2009) High-dose deslorata-dine decreases wheal volume and improves cold provocation thresholds compared with standard-dose treatment in patients with acquired cold urticaria: A randomized, placebo-controlled, crossover study. J. Allergy Clin. Immunol. 123: 672-679.
    • (2009) J. Allergy Clin. Immunol. , vol.123 , pp. 672-679
    • Siebenhaar, F.1    Degener, F.2    Zuberbier, T.3    Martus, P.4    Maurer, M.5
  • 343
    • 66049086427 scopus 로고    scopus 로고
    • Similar itch and nociceptive sensa-tions evoked by punctate cutaneous application of capsaicin, histamine and cowhage
    • Sikand P, Shimada SG, Green BG and LaMotte RH (2009) Similar itch and nociceptive sensa-tions evoked by punctate cutaneous application of capsaicin, histamine and cowhage. Pain 144: 66-75.
    • (2009) Pain , vol.144 , pp. 66-75
    • Sikand, P.1    Shimada, S.G.2    Green, B.G.3    LaMotte, R.H.4
  • 345
    • 8644255952 scopus 로고    scopus 로고
    • Advances in H1-antihistamines
    • Simons FE (2004) Advances in H1-antihistamines. N. Engl. J. Med. 351: 2203-2217.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 2203-2217
    • Simons, F.E.1
  • 346
    • 85096495210 scopus 로고    scopus 로고
    • Histamine and H1-antihistamines: Celebrating a century of progress
    • Simons FER and Simons KJ (2011) Histamine and H1-antihistamines: Celebrating a century of progress. J. Allergy Clin. Immunol. 128:1139-1150.e1134.
    • (2011) J. Allergy Clin. Immunol. , vol.128 , pp. 1139.e1134-1150.e1134
    • Simons, F.E.R.1    Simons, K.J.2
  • 347
    • 0028598432 scopus 로고
    • Budesonide and terfenadine, separately and in combination, in the treat-ment of hay fever
    • Simpson RJ (1994) Budesonide and terfenadine, separately and in combination, in the treat-ment of hay fever. Ann. Allergy 73: 497-502.
    • (1994) Ann. Allergy , vol.73 , pp. 497-502
    • Simpson, R.J.1
  • 351
    • 0041885423 scopus 로고    scopus 로고
    • Randomized, double-masked com-parison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models
    • Spangler DL, Abelson MB, Ober A and Gotnes PJ (2003) Randomized, double-masked com-parison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models. Clin. Ther. 25: 2245-2267.
    • (2003) Clin. Ther. , vol.25 , pp. 2245-2267
    • Spangler, D.L.1    Abelson, M.B.2    Ober, A.3    Gotnes, P.J.4
  • 352
    • 0034869181 scopus 로고    scopus 로고
    • Evaluation of the efficacy of olopatadine hydro-chloride 0.1% ophthalmic solution and azelastine hydrochloride 0.05% ophthalmic solution in the conjunctival allergen challenge model
    • Spangler DL, Bensch G and Berdy GJ (2001) Evaluation of the efficacy of olopatadine hydro-chloride 0.1% ophthalmic solution and azelastine hydrochloride 0.05% ophthalmic solution in the conjunctival allergen challenge model. Clin. Ther. 23: 1272-1280.
    • (2001) Clin. Ther. , vol.23 , pp. 1272-1280
    • Spangler, D.L.1    Bensch, G.2    Berdy, G.J.3
  • 354
    • 0001180589 scopus 로고
    • Action of thymoxyethyldiethylamine (F 929) and other phenol ethers on anaphylactic shock in guinea pigs
    • Staub AM and Bovet D (1937) Action of thymoxyethyldiethylamine (F 929) and other phenol ethers on anaphylactic shock in guinea pigs. C. R. Seances Soc. Biol. Fil. 125: 818-821.
    • (1937) C. R. Seances Soc. Biol. Fil. , vol.125 , pp. 818-821
    • Staub, A.M.1    Bovet, D.2
  • 358
    • 1642295821 scopus 로고    scopus 로고
    • Pruritus-associated response mediated by cutaneous histamine H3 receptors
    • Sugimoto Y, Iba Y, Nakamura Y, Kayasuga R and Kamei C (2004) Pruritus-associated response mediated by cutaneous histamine H3 receptors. Clin. Exp. Allergy 34: 456-459.
    • (2004) Clin. Exp. Allergy , vol.34 , pp. 456-459
    • Sugimoto, Y.1    Iba, Y.2    Nakamura, Y.3    Kayasuga, R.4    Kamei, C.5
  • 359
    • 0022966509 scopus 로고
    • Artificial food additive intolerance in patients with angio-oedema and urticaria
    • Supramaniam G and Warner JO (1986) Artificial food additive intolerance in patients with angio-oedema and urticaria. Lancet 2: 907-909.
    • (1986) Lancet , vol.2 , pp. 907-909
    • Supramaniam, G.1    Warner, J.O.2
  • 360
    • 80052035797 scopus 로고    scopus 로고
    • Histamine H4 receptor antagonist reduces dermal inflammation and pruritus in a hapten-induced experimental model
    • Suwa E, Yamaura K, Oda M, Namiki T and Ueno K (2011) Histamine H4 receptor antagonist reduces dermal inflammation and pruritus in a hapten-induced experimental model. Eur. J. Pharmacol. 667: 383-388.
    • (2011) Eur. J. Pharmacol. , vol.667 , pp. 383-388
    • Suwa, E.1    Yamaura, K.2    Oda, M.3    Namiki, T.4    Ueno, K.5
  • 363
    • 38749146486 scopus 로고    scopus 로고
    • Olopatadine ameliorates rat experi-mental cutaneous inflammation by improving skin barrier function
    • Tamura T, Matsubara M, Amano T and Chida M (2008) Olopatadine ameliorates rat experi-mental cutaneous inflammation by improving skin barrier function. Pharmacology 81: 118-126.
    • (2008) Pharmacology , vol.81 , pp. 118-126
    • Tamura, T.1    Matsubara, M.2    Amano, T.3    Chida, M.4
  • 365
    • 17144393764 scopus 로고    scopus 로고
    • Histamine receptors that influence blockage of the normal human nasal airway
    • Taylor-Clark T, Sodha R, Warner B and Foreman J (2005) Histamine receptors that influence blockage of the normal human nasal airway. Br. J. Pharmacol. 144: 867-874.
    • (2005) Br. J. Pharmacol. , vol.144 , pp. 867-874
    • Taylor-Clark, T.1    Sodha, R.2    Warner, B.3    Foreman, J.4
  • 366
    • 78651238610 scopus 로고    scopus 로고
    • Histamine in the regulation of wakefulness
    • Thakkar MM (2011) Histamine in the regulation of wakefulness. Sleep Med. Rev. 15: 65-74.
    • (2011) Sleep Med. Rev. , vol.15 , pp. 65-74
    • Thakkar, M.M.1
  • 368
    • 37749048627 scopus 로고    scopus 로고
    • The role of histamine H1 and H4 recep-tors in allergic inflammation: The search for new antihistamines
    • Thurmond RL, Gelfand EW and Dunford PJ (2008) The role of histamine H1 and H4 recep-tors in allergic inflammation: The search for new antihistamines. Nat. Rev. Drug Discov. 7: 41-53.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 41-53
    • Thurmond, R.L.1    Gelfand, E.W.2    Dunford, P.J.3
  • 369
    • 79951611143 scopus 로고    scopus 로고
    • The safety and efficacy of alcaftadine 0.25% ophthalmic solution for the prevention of itching associated with allergic conjunctivitis
    • Torkildsen G and Shedden A (2011) The safety and efficacy of alcaftadine 0.25% ophthalmic solution for the prevention of itching associated with allergic conjunctivitis. Curr. Med. Res. Opin. 27: 623-631.
    • (2011) Curr. Med. Res. Opin. , vol.27 , pp. 623-631
    • Torkildsen, G.1    Shedden, A.2
  • 370
    • 0018067018 scopus 로고
    • Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramine
    • Tran VT, Chang RS and Snyder SH (1978) Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramine. Proc. Natl. Acad. Sci. USA 75: 6290-6294.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 6290-6294
    • Tran, V.T.1    Chang, R.S.2    Snyder, S.H.3
  • 371
    • 33750094232 scopus 로고
    • Action of histamine and 5-hydroxytryptamine (5-HT) on isolated mammalian atria
    • Trendelenburg U and Hobbs RD (1960) Action of histamine and 5-hydroxytryptamine (5-HT) on isolated mammalian atria. J. Pharmacol. Exp. Ther. 130: 450-460.
    • (1960) J. Pharmacol. Exp. Ther. , vol.130 , pp. 450-460
    • Trendelenburg, U.1    Hobbs, R.D.2
  • 373
    • 0020064217 scopus 로고
    • Reduced histamine reaction in atopic dermatitis
    • Uehara M (1982) Reduced histamine reaction in atopic dermatitis. Arch. Dermatol. 118: 244-245.
    • (1982) Arch. Dermatol. , vol.118 , pp. 244-245
    • Uehara, M.1
  • 374
    • 23844526198 scopus 로고    scopus 로고
    • The time course of the bilateral release of cytokines and mediators after unilateral nasal allergen challenge
    • Wagenmann M, Schumacher L and Bachert C (2005) The time course of the bilateral release of cytokines and mediators after unilateral nasal allergen challenge. Allergy 60: 1132-1138.
    • (2005) Allergy , vol.60 , pp. 1132-1138
    • Wagenmann, M.1    Schumacher, L.2    Bachert, C.3
  • 376
    • 0035100042 scopus 로고    scopus 로고
    • Effect of cetirizine, levocetirizine, and dextrocetirizine on histamine-induced nasal response in healthy adult volunteers
    • Wang DY, Hanotte F, De VC and Clement P (2001) Effect of cetirizine, levocetirizine, and dextrocetirizine on histamine-induced nasal response in healthy adult volunteers. Allergy (Cph) 56: 339-343.
    • (2001) Allergy (Cph) , vol.56 , pp. 339-343
    • Wang, D.Y.1    Hanotte, F.2    De, V.C.3    Clement, P.4
  • 377
    • 12444320303 scopus 로고    scopus 로고
    • Desloratadine pre-vents compound 48/80-induced mast cell degranulation: Visualization using a vital fluo-rescent dye technique
    • Wang YH, Tache Y, Harris AG, Kreutner W, Daly AF and Wei JY (2005) Desloratadine pre-vents compound 48/80-induced mast cell degranulation: Visualization using a vital fluo-rescent dye technique. Allergy 60: 117-124.
    • (2005) Allergy , vol.60 , pp. 117-124
    • Wang, Y.H.1    Tache, Y.2    Harris, A.G.3    Kreutner, W.4    Daly, A.F.5    Wei, J.Y.6
  • 378
    • 0032512287 scopus 로고    scopus 로고
    • Intranasal corticosteroids versus oral H1 recep-tor antagonists in allergic rhinitis: Systematic review of randomised controlled trials
    • Weiner JM, Abramson MJ and Puy RM (1998) Intranasal corticosteroids versus oral H1 recep-tor antagonists in allergic rhinitis: Systematic review of randomised controlled trials. Br. Med. J. 317: 1624-1629.
    • (1998) Br. Med. J. , vol.317 , pp. 1624-1629
    • Weiner, J.M.1    Abramson, M.J.2    Puy, R.M.3
  • 379
    • 84859957028 scopus 로고    scopus 로고
    • Randomized clinical study of a histamine H3 receptor antagonist for the treatment of adults with attention-deficit hyperactivity disorder
    • Weisler RH, Pandina GJ, Daly EJ, Cooper K and Gassmann-Mayer C (2012) Randomized clinical study of a histamine H3 receptor antagonist for the treatment of adults with attention-deficit hyperactivity disorder. CNS Drugs 26: 421-434.
    • (2012) CNS Drugs , vol.26 , pp. 421-434
    • Weisler, R.H.1    Pandina, G.J.2    Daly, E.J.3    Cooper, K.4    Gassmann-Mayer, C.5
  • 380
    • 0030709263 scopus 로고    scopus 로고
    • Can a serotonin type 3 (5-HT3) receptor antag-onist reduce experimentally-induced itch?
    • Weisshaar E, Ziethen B and Gollnick H (1997) Can a serotonin type 3 (5-HT3) receptor antag-onist reduce experimentally-induced itch? Inflamm. Res. 46: 412-416.
    • (1997) Inflamm. Res. , vol.46 , pp. 412-416
    • Weisshaar, E.1    Ziethen, B.2    Gollnick, H.3
  • 381
  • 382
    • 70350068543 scopus 로고    scopus 로고
    • Desloratadine inhibits human skin mast cell activation and histamine release
    • Weller K and Maurer M (2009) Desloratadine inhibits human skin mast cell activation and histamine release. J. Invest. Dermatol. 129: 2723-2726.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 2723-2726
    • Weller, K.1    Maurer, M.2
  • 383
    • 84855773018 scopus 로고
    • Observations on the nature of the antagonism of histamine by beta-dimethylaminoethyl benzhydryl ether (benadryl)
    • Wells JA, Bull HB, Dragstedt CA, Morris HC (1945) Observations on the nature of the antagonism of histamine by beta-dimethylaminoethyl benzhydryl ether (benadryl). J. Pharmacol. Exp. Ther. 85: 122-128.
    • (1945) J. Pharmacol. Exp. Ther. , vol.85 , pp. 122-128
    • Wells, J.A.1    Bull, H.B.2    Dragstedt, C.A.3    Morris, H.C.4
  • 384
    • 1242272163 scopus 로고    scopus 로고
    • Efficacy and tol-erability of ophthalmic epinastine: A randomized, double-masked, parallel-group, active- and vehicle-controlled environmental trial in patients with seasonal allergic con-junctivitis
    • Whitcup SM, Bradford R, Lue J, Schiffman RM and Abelson MB (2004) Efficacy and tol-erability of ophthalmic epinastine: A randomized, double-masked, parallel-group, active- and vehicle-controlled environmental trial in patients with seasonal allergic con-junctivitis. Clin. Ther. 26: 29-34.
    • (2004) Clin. Ther. , vol.26 , pp. 29-34
    • Whitcup, S.M.1    Bradford, R.2    Lue, J.3    Schiffman, R.M.4    Abelson, M.B.5
  • 386
    • 0021927412 scopus 로고
    • Comparison of the clinico-pathologic features of primary sclerosing cholangitis and primary biliary cirrhosis
    • Wiesner RH, LaRusso NF, Ludwig J and Dickson ER (1985) Comparison of the clinico-pathologic features of primary sclerosing cholangitis and primary biliary cirrhosis. Gastroenterology 88: 108-114.
    • (1985) Gastroenterology , vol.88 , pp. 108-114
    • Wiesner, R.H.1    LaRusso, N.F.2    Ludwig, J.3    Dickson, E.R.4
  • 387
    • 19644366045 scopus 로고    scopus 로고
    • Clinical practice. Atopic dermatitis
    • Williams HC (2005) Clinical practice. Atopic dermatitis. N. Engl. J. Med. 352: 2314-2324.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 2314-2324
    • Williams, H.C.1
  • 388
    • 0036408830 scopus 로고    scopus 로고
    • Effects of fexofenadine and deslo-ratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis
    • Wilson AM, Haggart K, Sims EJ and Lipworth BJ (2002) Effects of fexofenadine and deslo-ratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis. Clin. Exp. Allergy 32: 1504-1509.
    • (2002) Clin. Exp. Allergy , vol.32 , pp. 1504-1509
    • Wilson, A.M.1    Haggart, K.2    Sims, E.J.3    Lipworth, B.J.4
  • 389
    • 84946384466 scopus 로고
    • Synthese des Imidazolyl-athylamins
    • Windaus A and Vogt W (1907) Synthese des Imidazolyl-athylamins. Ber. Dtsch. Chem. Ges. 40: 3691-3695.
    • (1907) Ber. Dtsch. Chem. Ges. , vol.40 , pp. 3691-3695
    • Windaus, A.1    Vogt, W.2
  • 391
    • 0019474303 scopus 로고
    • Pharmacologic prophylaxis of allergic rhini-tis: Relative efficacy of hydroxyzine and chlorpheniramine
    • Wong L, Hendeles L and Weinberger M (1981) Pharmacologic prophylaxis of allergic rhini-tis: Relative efficacy of hydroxyzine and chlorpheniramine. J. Allergy Clin. Immunol. 67: 223-228.
    • (1981) J. Allergy Clin. Immunol. , vol.67 , pp. 223-228
    • Wong, L.1    Hendeles, L.2    Weinberger, M.3
  • 392
    • 0029784096 scopus 로고    scopus 로고
    • Histamine and the nasal vasculature: The influence of H1 and H2-histamine receptor antagonism
    • Wood-Baker R, Lau L and Howarth PH (1996) Histamine and the nasal vasculature: The influence of H1 and H2-histamine receptor antagonism. Clin. Otolaryngol. Allied Sci. 21: 348-352.
    • (1996) Clin. Otolaryngol. Allied Sci. , vol.21 , pp. 348-352
    • Wood-Baker, R.1    Lau, L.2    Howarth, P.H.3
  • 393
  • 394
    • 0037130988 scopus 로고    scopus 로고
    • Characteristics of recombinantly expressed rat and human histamine H3 receptors
    • Wulff BS, Hastrup S and Rimvall K (2002) Characteristics of recombinantly expressed rat and human histamine H3 receptors. Eur. J. Pharmacol. 453: 33-41.
    • (2002) Eur. J. Pharmacol. , vol.453 , pp. 33-41
    • Wulff, B.S.1    Hastrup, S.2    Rimvall, K.3
  • 395
    • 0015524137 scopus 로고
    • Effects in man of histamine H2-receptor blockade by burimamide
    • Wyllie JH, Hesselbo T and Black JW (1972) Effects in man of histamine H2-receptor blockade by burimamide. Lancet 2: 1117-1120.
    • (1972) Lancet , vol.2 , pp. 1117-1120
    • Wyllie, J.H.1    Hesselbo, T.2    Black, J.W.3
  • 396
    • 68549136644 scopus 로고    scopus 로고
    • Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist
    • Yamaura K, Oda M, Suwa E, Suzuki M, Sato H and Ueno K (2009) Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist. J. Toxicol. Sci. 34: 427-431.
    • (2009) J. Toxicol. Sci. , vol.34 , pp. 427-431
    • Yamaura, K.1    Oda, M.2    Suwa, E.3    Suzuki, M.4    Sato, H.5    Ueno, K.6
  • 397
    • 0036878425 scopus 로고    scopus 로고
    • Intranasal corticosteroids versus topical H1 receptor antago-nists for the treatment of allergic rhinitis: A systematic review with meta-analysis
    • Yanez A and Rodrigo GJ (2002) Intranasal corticosteroids versus topical H1 receptor antago-nists for the treatment of allergic rhinitis: A systematic review with meta-analysis. Ann. Allergy Asthma Immunol. 89: 479-484.
    • (2002) Ann. Allergy Asthma Immunol. , vol.89 , pp. 479-484
    • Yanez, A.1    Rodrigo, G.J.2
  • 398
    • 0042672615 scopus 로고    scopus 로고
    • Comparative study of 0.1% olopatadine hydrochloride and 0.5% ketorolac trometh-amine in the treatment of seasonal allergic conjunctivitis
    • Yaylali V, Demirlenk I, Tatlipinar S, Ozbay D, Esme A, Yildirim C and Ozden S (2003) Comparative study of 0.1% olopatadine hydrochloride and 0.5% ketorolac trometh-amine in the treatment of seasonal allergic conjunctivitis. Acta Ophthalmol. Scand. 81: 378-382.
    • (2003) Acta Ophthalmol. Scand. , vol.81 , pp. 378-382
    • Yaylali, V.1    Demirlenk, I.2    Tatlipinar, S.3    Ozbay, D.4    Esme, A.5    Yildirim, C.6    Ozden, S.7
  • 399
  • 400
    • 33947380242 scopus 로고    scopus 로고
    • Scratching and nox-ious heat stimuli inhibit itch in humans: A psychophysical study
    • Yosipovitch G, Duque MI, Fast K, Dawn AG and Coghill RC (2007) Scratching and nox-ious heat stimuli inhibit itch in humans: A psychophysical study. Br. J. Dermatol. 156: 629-634.
    • (2007) Br. J. Dermatol. , vol.156 , pp. 629-634
    • Yosipovitch, G.1    Duque, M.I.2    Fast, K.3    Dawn, A.G.4    Coghill, R.C.5
  • 401
    • 33644817780 scopus 로고    scopus 로고
    • Noxious heat and scratching decrease hista-mine-induced itch and skin blood flow
    • Yosipovitch G, Fast K and Bernhard JD (2005) Noxious heat and scratching decrease hista-mine-induced itch and skin blood flow. J. Invest. Dermatol. 125: 1268-1272.
    • (2005) J. Invest. Dermatol. , vol.125 , pp. 1268-1272
    • Yosipovitch, G.1    Fast, K.2    Bernhard, J.D.3
  • 402
    • 0033729496 scopus 로고    scopus 로고
    • The prevalence and clinical characteristics of pruritus among patients with extensive psoriasis
    • Yosipovitch G, Goon A, Wee J, Chan YH and Goh CL (2000) The prevalence and clinical characteristics of pruritus among patients with extensive psoriasis. Br. J. Dermatol. 143: 969-973.
    • (2000) Br. J. Dermatol. , vol.143 , pp. 969-973
    • Yosipovitch, G.1    Goon, A.2    Wee, J.3    Chan, Y.H.4    Goh, C.L.5
  • 405
    • 0031880171 scopus 로고    scopus 로고
    • Topical corticosteroids for mycosis fun-goides. Experience in 79 patients
    • Zackheim HS, Kashani-Sabet M and Amin S (1998) Topical corticosteroids for mycosis fun-goides. Experience in 79 patients. Arch. Dermatol. 134: 949-954.
    • (1998) Arch. Dermatol. , vol.134 , pp. 949-954
    • Zackheim, H.S.1    Kashani-Sabet, M.2    Amin, S.3
  • 407
    • 84856432800 scopus 로고    scopus 로고
    • Cost, utilization, and patterns of medication use associated with chronic idiopathic urticaria
    • Zazzali JL, Broder MS, Chang E, Chiu MW and Hogan DJ (2012) Cost, utilization, and patterns of medication use associated with chronic idiopathic urticaria. Ann. Allergy Asthma Immunol. 108: 98-102.
    • (2012) Ann. Allergy Asthma Immunol. , vol.108 , pp. 98-102
    • Zazzali, J.L.1    Broder, M.S.2    Chang, E.3    Chiu, M.W.4    Hogan, D.J.5
  • 408
    • 0035126498 scopus 로고    scopus 로고
    • Cloning, expression, and pharmacological characterization of a novel human histamine receptor
    • Zhu Y, Michalovich D, Wu H, Tan KB, Dytko GM, Mannan IJ, Boyce R et al. (2001) Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Mol. Pharmacol. 59: 434-441.
    • (2001) Mol. Pharmacol. , vol.59 , pp. 434-441
    • Zhu, Y.1    Michalovich, D.2    Wu, H.3    Tan, K.B.4    Dytko, G.M.5    Mannan, I.J.6    Boyce, R.7
  • 410
    • 0023779484 scopus 로고
    • Effect of levocabastine, a new H1 antagonist, in a conjunctival provocation test with allergens
    • Zuber P and Pecoud A (1988) Effect of levocabastine, a new H1 antagonist, in a conjunctival provocation test with allergens. J. Allergy Clin. Immunol. 82: 590-594.
    • (1988) J. Allergy Clin. Immunol. , vol.82 , pp. 590-594
    • Zuber, P.1    Pecoud, A.2
  • 411
    • 83955162925 scopus 로고    scopus 로고
    • Pharmacological rationale for the treatment of chronic urticaria with sec-ond-generation non-sedating antihistamines at higher-than-standard doses
    • Zuberbier T (2012) Pharmacological rationale for the treatment of chronic urticaria with sec-ond-generation non-sedating antihistamines at higher-than-standard doses. J. Eur. Acad. Dermatol. Venereol. 26: 9-18.
    • (2012) J. Eur. Acad. Dermatol. Venereol. , vol.26 , pp. 9-18
    • Zuberbier, T.1
  • 414
    • 34447521676 scopus 로고    scopus 로고
    • Urticaria: Current opinions about etiology, diagnosis and therapy
    • Zuberbier T and Maurer M (2007) Urticaria: Current opinions about etiology, diagnosis and therapy. Acta Derm. Venereol. 87: 196-205.
    • (2007) Acta Derm. Venereol. , vol.87 , pp. 196-205
    • Zuberbier, T.1    Maurer, M.2
  • 415
    • 79960741491 scopus 로고    scopus 로고
    • Antihistamines in the treatment of urticaria
    • Zuberbier T and Maurer M (2010) Antihistamines in the treatment of urticaria. Adv. Exp. Med. Biol. 709: 67-72.
    • (2010) Adv. Exp. Med. Biol. , vol.709 , pp. 67-72
    • Zuberbier, T.1    Maurer, M.2
  • 416
    • 0142213898 scopus 로고    scopus 로고
    • Prevalence and charac-terization of uremic pruritus in patients undergoing hemodialysis: Uremic pruritus is still a major problem for patients with end-stage renal disease
    • Zucker I, Yosipovitch G, David M, Gafter U and Boner G (2003) Prevalence and charac-terization of uremic pruritus in patients undergoing hemodialysis: Uremic pruritus is still a major problem for patients with end-stage renal disease. J. Am. Acad. Dermatol. 49: 842-846.
    • (2003) J. Am. Acad. Dermatol. , vol.49 , pp. 842-846
    • Zucker, I.1    Yosipovitch, G.2    David, M.3    Gafter, U.4    Boner, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.