The dual H3/4R antagonist thioperamide does not fully mimic the effects of the 'standard' H4R antagonist JNJ 7777120 in experimental murine asthma

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 386, Issue 11, 2013, Pages 983-990

  Neumann, Detlef ^a   Beermann, Silke ^a   Burhenne, Heike ^a   Glage, Silke ^a   Hartwig, Christina ^a   Seifert, Roland ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Histamine H4 receptor; JNJ 5207852; JNJ 7777120; Mouse; Ovalbumine induced asthma; Thioperamide

Indexed keywords

1 (5 CHLORO 2 INDOLYLCARBONYL) 4 METHYLPIPERAZINE; HISTAMINE; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; HISTAMINE H4 RECEPTOR; HISTAMINE H4 RECEPTOR ANTAGONIST; IMMUNOGLOBULIN E; OVALBUMIN; THIOPERAMIDE; 1-((5-CHLORO-1H-INDOL-2-YL)CARBONYL)-4-METHYLPIPERAZINE; G PROTEIN COUPLED RECEPTOR; HISTAMINE RECEPTOR; HRH4 PROTEIN, HUMAN; INDOLE DERIVATIVE; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BAGG ALBINO MOUSE; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG RECEPTOR BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHILIA; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LUNG LAVAGE; LUNG PARENCHYMA; MASS SPECTROMETRY; MOUSE; NONHUMAN; PLASMA; SENSITIZATION; TREATMENT OUTCOME; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; CYTOLOGY; DISEASE MODEL; IMMUNOLOGY; LUNG; METABOLISM; PATHOLOGY;

ANIMALS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; DISEASE MODELS, ANIMAL; EOSINOPHILIA; FEMALE; HISTAMINE H3 ANTAGONISTS; IMMUNOGLOBULIN E; INDOLES; LUNG; MICE; MICE, INBRED BALB C; OVALBUMIN; PIPERAZINES; PIPERIDINES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE;

MLCS; MLOWN;

EID: 84885952222     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-013-0898-4     Document Type: Article

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