The first potent and selective non-imidazole human histamine H4 receptor antagonists

Journal of Medicinal Chemistry

Volumn 46, Issue 19, 2003, Pages 3957-3960

  Jablonowski, Jill A ^a   Grice, Cheryl A ^a   Chai, Wenying ^a   Dvorak, Curt A ^a   Venable, Jennifer D ^a   Kwok, Annette K ^a   Ly, Kiev S ^a   Wei, Jianmei ^a   Baker, Sherry M ^a   Desai, Pragnya J ^a   Jiang, Wen ^a   Wilson, Sandy J ^a   Thurmond, Robin L ^a   Karlsson, Lars ^a   Edwards, James P ^a   Lovenberg, Timothy W ^a   Carruthers, Nicholas I ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHISTAMINIC AGENT; CYCLIC AMP; FORSKOLIN; HISTAMINE; HISTAMINE H4 RECEPTOR; HISTAMINE H4 RECEPTOR ANTAGONIST; INDOLYLPIPERAZINE; JNJ 7777120; N METHYLPIPERAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; HUMAN; HUMAN CELL; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTAMINE ANTAGONISTS; HUMANS; INDOLES; KINETICS; LIGANDS; NEURONS; PIPERAZINES; RADIOLIGAND ASSAY; RATS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 0141455895     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0341047     Document Type: Article

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