Opposite effects of mepyramine on JNJ 7777120-induced amelioration of experimentally induced asthma in mice in sensitization and provocation

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Beermann, Silke ^a   Glage, Silke ^a   Jonigk, Danny ^a   Seifert, Roland ^a   Neumann, Detlef ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 CHLORO 2 INDOLYLCARBONYL) 4 METHYLPIPERAZINE; GAMMA INTERFERON; HISTAMINE H1 RECEPTOR; HISTAMINE H4 RECEPTOR; IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 2; INTERLEUKIN 5; INTERLEUKIN 6; MEPYRAMINE; OVALBUMIN; 1 ((5 CHLORO 1H INDOL 2 YL)CARBONYL) 4 METHYLPIPERAZINE; 1-((5-CHLORO-1H-INDOL-2-YL)CARBONYL)-4-METHYLPIPERAZINE; ANTIHISTAMINIC AGENT; CYTOKINE; G PROTEIN COUPLED RECEPTOR; HISTAMINE H2 RECEPTOR ANTAGONIST; HISTAMINE RECEPTOR; HRH4 PROTEIN, MOUSE; INDOLE DERIVATIVE; PIPERAZINE DERIVATIVE;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; BRONCHIOLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DRUG ANTAGONISM; EOSINOPHILIA; FEMALE; HISTOPATHOLOGY; IMMUNE RESPONSE; LEUKOCYTE; LUNG INFILTRATE; LUNG LAVAGE; LUNG PARENCHYMA; LYMPHOID CELL; MONOCYTE; MOUSE; NONHUMAN; PNEUMONIA; PROTEIN FUNCTION; PROVOCATION TEST; SENSITIZATION; TH2 CELL; ANIMAL; BAGG ALBINO MOUSE; BLOOD; BRONCHUS HYPERREACTIVITY; CYTOLOGY; DRUG ADMINISTRATION; DRUG COMBINATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; IMMUNIZATION; IMMUNOLOGY; INHALATION TEST; METABOLISM; TIME; TREATMENT OUTCOME;

MURINAE; MUS;

ANIMALS; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHIAL PROVOCATION TESTS; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HISTAMINE ANTAGONISTS; HISTAMINE H2 ANTAGONISTS; HUMANS; IMMUNIZATION; IMMUNOGLOBULIN E; INDOLES; MICE; MICE, INBRED BALB C; OVALBUMIN; PIPERAZINES; PYRILAMINE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; TIME FACTORS; TREATMENT OUTCOME;

EID: 84855824380     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030285     Document Type: Article

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