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Volumn 22, Issue 2, 2015, Pages 264-289

Targeting the NFκB signaling pathways for breast cancer prevention and therapy

Author keywords

Breast cancer; Inflammation; Nf B; Transcription factor

Indexed keywords

ANDROGEN RECEPTOR; AROMATIC HYDROCARBON RECEPTOR; BETA ARRESTIN; CALMODULIN; CYCLIN DEPENDENT KINASE 2; CYCLIN E; DAXX PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ESTROGEN RECEPTOR; HEAT SHOCK PROTEIN 27; HISTONE DEACETYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NOTCH1 RECEPTOR; PROTEASOME; PROTEIN C FOS; PROTEIN C JUN; PROTEIN MDM2; PROTEIN P53; S6 KINASE; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR SP1; ANTINEOPLASTIC AGENT;

EID: 84925445643     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/0929867321666141106124315     Document Type: Article
Times cited : (205)

References (349)
  • 1
    • 0036484856 scopus 로고    scopus 로고
    • Chronic inflammation and cancer
    • 229; discussion 230-232
    • Shacter, E.; Weitzman, S. A. Chronic inflammation and cancer. Oncology (Williston Park), 2002, 16(2), 217-226, 229; discussion 230-232.
    • (2002) Oncology (Williston Park) , vol.16 , Issue.2 , pp. 217-226
    • Shacter, E.1    Weitzman, S.A.2
  • 2
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov, S. I.; Greten, F. R.; Karin, M. Immunity, inflammation, and cancer. Cell, 2010, 140(6), 883-899.
    • (2010) Cell , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 3
    • 33646160623 scopus 로고    scopus 로고
    • Inflammation, a key event in cancer development
    • Lu, H.; Ouyang, W.; Huang, C. Inflammation, a key event in cancer development. Mol. Cancer Res., 2006, 4(4), 221-233.
    • (2006) Mol. Cancer Res. , vol.4 , Issue.4 , pp. 221-233
    • Lu, H.1    Ouyang, W.2    Huang, C.3
  • 4
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill, F.; Mantovani, A. Inflammation and cancer: back to Virchow? Lancet, 2001, 357(9255), 539-545.
    • (2001) Lancet , vol.357 , Issue.9255 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 5
    • 44949225152 scopus 로고    scopus 로고
    • Inflammatory bowel disease and inflammationassociated colon cancer: Partners in crime
    • Danese, S. Inflammatory bowel disease and inflammationassociated colon cancer: partners in crime. Curr. Drug Targets, 2008, 9(5), 360.
    • (2008) Curr. Drug Targets , vol.9 , Issue.5 , pp. 360
    • Danese, S.1
  • 6
    • 77952305365 scopus 로고    scopus 로고
    • Roles for inflammation and regulatory T cells in colon cancer
    • Erdman, S. E.; Poutahidis, T. Roles for inflammation and regulatory T cells in colon cancer. Toxicol. Pathol, 2010, 38(1), 76-87.
    • (2010) Toxicol. Pathol , vol.38 , Issue.1 , pp. 76-87
    • Erdman, S.E.1    Poutahidis, T.2
  • 8
    • 79955585058 scopus 로고    scopus 로고
    • Cytokines, inflammation and colon cancer
    • Klampfer, L. Cytokines, inflammation and colon cancer. Curr. Cancer Drug Targets, 2011, 11(4), 451-464.
    • (2011) Curr. Cancer Drug Targets , vol.11 , Issue.4 , pp. 451-464
    • Klampfer, L.1
  • 9
    • 84883167708 scopus 로고    scopus 로고
    • Helicobacter pylori-induced chronic gastritis and assessing risks for gastric cancer
    • Carrasco, G.; Corvalan, A. H. Helicobacter pylori-Induced Chronic Gastritis and Assessing Risks for Gastric Cancer. Gastroenterol. Res. Pract., 2013, 2013, 393015.
    • (2013) Gastroenterol. Res. Pract. , vol.2013 , pp. 393015
    • Carrasco, G.1    Corvalan, A.H.2
  • 10
    • 84884810711 scopus 로고    scopus 로고
    • Helicobacter pylori promotes invasion and metastasis of gastric cancer cells through activation of AP-1 and up-regulation of CACUL1
    • Kong, Y.; Ma, L. Q.; Bai, P. S.; Da, R.; Sun, H.; Qi, X. G.; Ma, J. Q.; Zhao, R. M.; Chen, N. Z.; Nan, K. J. Helicobacter pylori promotes invasion and metastasis of gastric cancer cells through activation of AP-1 and up-regulation of CACUL1. Int. J. Biochem. Cell Biol., 2013, 45(11), 2666-2678.
    • (2013) Int. J. Biochem. Cell Biol. , vol.45 , Issue.11 , pp. 2666-2678
    • Kong, Y.1    Ma, L.Q.2    Bai, P.S.3    Da, R.4    Sun, H.5    Qi, X.G.6    Ma, J.Q.7    Zhao, R.M.8    Chen, N.Z.9    Nan, K.J.10
  • 11
    • 84895929897 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in human gastric cancer cell lines induced by TNF-alphainducing protein of Helicobacter pylori
    • Watanabe, T.; Takahashi, A.; Suzuki, K; Kurusu-Kanno, M.; Yamaguchi, K; Fujiki, H.; Suganuma, M. Epithelial-mesenchymal transition in human gastric cancer cell lines induced by TNF-alphainducing protein of Helicobacter pylori. Int. J. Cancer., 2014, 134(10), 2373-2382.
    • (2014) Int. J. Cancer. , vol.134 , Issue.10 , pp. 2373-2382
    • Watanabe, T.1    Takahashi, A.2    Suzuki, K.3    Kurusu-Kanno, M.4    Yamaguchi, K.5    Fujiki, H.6    Suganuma, M.7
  • 12
    • 19344365408 scopus 로고    scopus 로고
    • De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent
    • De Visser, K. E.; Korets, L. V.; Coussens, L. M. De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent. Cancer cell, 2005, 7(5), 411-423.
    • (2005) Cancer Cell , vol.7 , Issue.5 , pp. 411-423
    • De Visser, K.E.1    Korets, L.V.2    Coussens, L.M.3
  • 14
    • 77957351501 scopus 로고    scopus 로고
    • Induction of epigenetic alterations by chronic inflammation and its significance on carcinogenesis
    • Niwa, T.; Ushijima, T. Induction of epigenetic alterations by chronic inflammation and its significance on carcinogenesis. Adv. Genet., 2010, 71, 41-56.
    • (2010) Adv. Genet. , vol.71 , pp. 41-56
    • Niwa, T.1    Ushijima, T.2
  • 16
    • 84899950470 scopus 로고    scopus 로고
    • Inflammation and pancreatic cancer: Disease promoter and new therapeutic target
    • Hamada, S.; Masamune, A.; Shimosegawa, T. Inflammation and pancreatic cancer: disease promoter and new therapeutic target. J. Gastroenterol., 2014, 49(4), 605-617.
    • (2014) J. Gastroenterol. , vol.49 , Issue.4 , pp. 605-617
    • Hamada, S.1    Masamune, A.2    Shimosegawa, T.3
  • 17
    • 84893434932 scopus 로고    scopus 로고
    • Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin
    • Kwon, O. J.; Zhang, L.; Ittmann, M. M.; Xin, L. Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin. Proc. Natl. Acad. Sci. USA., 2014, 111(5), E592-600.
    • (2014) Proc. Natl. Acad. Sci. USA. , vol.111 , Issue.5 , pp. E592-E600
    • Kwon, O.J.1    Zhang, L.2    Ittmann, M.M.3    Xin, L.4
  • 18
    • 2942682649 scopus 로고    scopus 로고
    • S-nitrosylation: Physiological regulation of NF-kappaB
    • Marshall, H. E.; Hess, D. T.; Stamler, J. S. S-nitrosylation: physiological regulation of NF-kappaB. Proc. Natl. Acad. Sci. USA, 2004, 101(24), 8841-8842.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , Issue.24 , pp. 8841-8842
    • Marshall, H.E.1    Hess, D.T.2    Stamler, J.S.3
  • 19
    • 33745489431 scopus 로고    scopus 로고
    • Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis
    • Kawanishi, S.; Hiraku, Y.; Pinlaor, S.; Ma, N. Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis. Biol. Chem., 2006, 387(4), 365-372.
    • (2006) Biol. Chem. , vol.387 , Issue.4 , pp. 365-372
    • Kawanishi, S.1    Hiraku, Y.2    Pinlaor, S.3    Ma, N.4
  • 21
    • 0033596124 scopus 로고    scopus 로고
    • Aberrant rel/nfkb genes and activity in human cancer
    • Rayet, B.; Gelinas, C. Aberrant rel/nfkb genes and activity in human cancer. Oncogene, 1999, 18(49), 6938-6947.
    • (1999) Oncogene , vol.18 , Issue.49 , pp. 6938-6947
    • Rayet, B.1    Gelinas, C.2
  • 22
    • 80052014052 scopus 로고    scopus 로고
    • Inflammation meets cancer, with NF-kB as the matchmaker
    • Ben-Neriah, Y.; Karin, M. Inflammation meets cancer, with NF-kB as the matchmaker. Nat Immunol, 2011, 12(8), 715-723.
    • (2011) Nat Immunol , vol.12 , Issue.8 , pp. 715-723
    • Ben-Neriah, Y.1    Karin, M.2
  • 23
    • 77953859606 scopus 로고    scopus 로고
    • NF-kappaB as a critical link between inflammation and cancer
    • Karin, M. NF-kappaB as a critical link between inflammation and cancer. Cold Spring Harb Perspect Biol, 2009, 1(5), a000141.
    • (2009) Cold Spring Harb Perspect Biol , vol.1 , Issue.5 , pp. a000141
    • Karin, M.1
  • 24
    • 84856213846 scopus 로고    scopus 로고
    • The diverse and complex roles of NF-kappaB subunits in cancer
    • Perkins N. D. The diverse and complex roles of NF-kappaB subunits in cancer, Nat. Rev. Cancer, 2012, 12, 121-132.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 121-132
    • Perkins, N.D.1
  • 25
    • 84883560456 scopus 로고    scopus 로고
    • Targeting the NFkB pathway in cancer therapy
    • Erstad, D. J.; Cusack Jr. J. C. Targeting the NFkB Pathway in Cancer Therapy, Surg. Oncol. Clin. N. Am., 2013, 22, 705-746.
    • (2013) Surg. Oncol. Clin. N. Am. , vol.22 , pp. 705-746
    • Erstad, D.J.1    Cusack, J.C.2
  • 26
    • 79953782203 scopus 로고    scopus 로고
    • NF-kappaB addiction and its role in cancer: 'One size does not fit all'
    • Chaturvedi, M. M.; Sung, B.; Yadav, V. R.; Kannappan, R.; Aggarwal, B. B. NF-kappaB addiction and its role in cancer: 'one size does not fit all'. Oncogene, 2011, 30(14), 1615-1630.
    • (2011) Oncogene , vol.30 , Issue.14 , pp. 1615-1630
    • Chaturvedi, M.M.1    Sung, B.2    Yadav, V.R.3    Kannappan, R.4    Aggarwal, B.B.5
  • 27
    • 80053122580 scopus 로고    scopus 로고
    • Colon cancer-derived factors activate NF-kappaB in myeloid cells via TLR2 to link inflammation and tumorigenesis
    • Maeda, S.; Hikiba, Y.; Sakamoto, K.; Nakagawa, H.; Hirata, Y.; Hayakawa, Y.; Akanuma, M. Colon cancer-derived factors activate NF-kappaB in myeloid cells via TLR2 to link inflammation and tumorigenesis. Mol. Med. Rep., 2011, 4(6), 1083-1088.
    • (2011) Mol. Med. Rep. , vol.4 , Issue.6 , pp. 1083-1088
    • Maeda, S.1    Hikiba, Y.2    Sakamoto, K.3    Nakagawa, H.4    Hirata, Y.5    Hayakawa, Y.6    Akanuma, M.7
  • 29
    • 84895071589 scopus 로고    scopus 로고
    • Activation of NF-kappaB: Bridging the gap between inflammation and cancer in colitis-mediated colon carcinogenesis
    • Setia, S.; Nehru, B.; Sanyal, S. N. Activation of NF-kappaB: Bridging the gap between inflammation and cancer in colitis-mediated colon carcinogenesis. Biomed. Pharmacother., 2014, 68(1), 119-128.
    • (2014) Biomed. Pharmacother. , vol.68 , Issue.1 , pp. 119-128
    • Setia, S.1    Nehru, B.2    Sanyal, S.N.3
  • 30
    • 84861716717 scopus 로고    scopus 로고
    • Crosstalk between NFkB and glucocorticoid signaling: A potential target of breast cancer therapy
    • Ling J.; Kumar R. Crosstalk between NFkB and glucocorticoid signaling: a potential target of breast cancer therapy, Cancer Lett., 2012, 322, 119-126.
    • (2012) Cancer Lett. , vol.322 , pp. 119-126
    • Ling, J.1    Kumar, R.2
  • 31
    • 0022481133 scopus 로고
    • Multiple nuclear factors interact with the immunoglobulin enhancer sequences
    • Sen, R.; Baltimore, D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell, 1986, 46(5), 705-716.
    • (1986) Cell , vol.46 , Issue.5 , pp. 705-716
    • Sen, R.1    Baltimore, D.2
  • 32
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh, S.; May, M. J.; Kopp, E. B. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Ann. Rev. Immunol, 1998, 16, 225-260.
    • (1998) Ann. Rev. Immunol , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 33
    • 0028971289 scopus 로고
    • Rel/NF-kappa B/I kappa B family: Intimate tales of association and dissociation
    • Verma, I. M.; Stevenson, J. K.; Schwarz, E. M.; Van Antwerp, D.; Miyamoto, S. Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. Genes. Dev., 1995, 9(22), 2723-2735.
    • (1995) Genes. Dev. , vol.9 , Issue.22 , pp. 2723-2735
    • Verma, I.M.1    Stevenson, J.K.2    Schwarz, E.M.3    Van Antwerp, D.4    Miyamoto, S.5
  • 34
    • 0029924035 scopus 로고    scopus 로고
    • A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit
    • Lin, L.; Ghosh, S. A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit. Mol. Cell Biol, 1996, 16(5), 2248-2254.
    • (1996) Mol. Cell Biol , vol.16 , Issue.5 , pp. 2248-2254
    • Lin, L.1    Ghosh, S.2
  • 35
    • 0023724778 scopus 로고
    • I kappa B: A specific inhibitor of the NF-kappa B transcription factor
    • Baeuerle, P. A.; Baltimore, D. I kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science, 1988, 242(4878), 540-546.
    • (1988) Science , vol.242 , Issue.4878 , pp. 540-546
    • Baeuerle, P.A.1    Baltimore, D.2
  • 36
    • 77957592789 scopus 로고    scopus 로고
    • Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
    • Gupta, S. C; Kim, J. H.; Prasad, S.; Aggarwal, B. B. Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals. Cancer Metas. Rev., 2010, 29(3), 405-434.
    • (2010) Cancer Metas. Rev. , vol.29 , Issue.3 , pp. 405-434
    • Gupta, S.C.1    Kim, J.H.2    Prasad, S.3    Aggarwal, B.B.4
  • 37
    • 34547598337 scopus 로고    scopus 로고
    • Multiple myeloma: Lusting for NF-kappaB
    • Gilmore, T. D. Multiple myeloma: lusting for NF-kappaB. Cancer cell 2007, 12(2), 95-97.
    • (2007) Cancer Cell , vol.12 , Issue.2 , pp. 95-97
    • Gilmore, T.D.1
  • 38
    • 11844251170 scopus 로고    scopus 로고
    • The NF-kappaB/IkappaB signaling system: A molecular target in breast cancer therapy
    • Wu, J. T.; Kral, J. G. The NF-kappaB/IkappaB signaling system: a molecular target in breast cancer therapy. J. Surg. Res., 2005, 123(1), 158-169.
    • (2005) J. Surg. Res. , vol.123 , Issue.1 , pp. 158-169
    • Wu, J.T.1    Kral, J.G.2
  • 42
    • 4344612243 scopus 로고    scopus 로고
    • NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
    • Huber, M. A.; Azoitei, N.; Baumann, B.; Grunert, S.; Sommer, A.; Pehamberger, H.; Kraut, N.; Beug, H.; Wirth, T. NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J. Clin. Invest., 2004, 114(4), 569-581.
    • (2004) J. Clin. Invest. , vol.114 , Issue.4 , pp. 569-581
    • Huber, M.A.1    Azoitei, N.2    Baumann, B.3    Grunert, S.4    Sommer, A.5    Pehamberger, H.6    Kraut, N.7    Beug, H.8    Wirth, T.9
  • 43
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: From innocent bystander to major culprit
    • Karin, M.; Cao, Y.; Greten, F. R.; Li, Z. W. NF-kappaB in cancer: from innocent bystander to major culprit. Nat. Rev. Cancer, 2002, 2(4), 301-310.
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.4 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 44
    • 84858718448 scopus 로고    scopus 로고
    • NF-kappaB and the link between inflammation and cancer
    • Di Donato, J. A.; Mercurio, F.; Karin, M. NF-kappaB and the link between inflammation and cancer. Immunol Rev., 2012, 246(1), 379-400.
    • (2012) Immunol Rev. , vol.246 , Issue.1 , pp. 379-400
    • Di Donato, J.A.1    Mercurio, F.2    Karin, M.3
  • 45
    • 0033587084 scopus 로고    scopus 로고
    • Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha
    • Cabannes, E.; Khan, G.; Aillet, F.; Jarrett, R. F.; Hay, R. T. Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha. Oncogene, 1999, 18, 3063-3070.
    • (1999) Oncogene , vol.18 , pp. 3063-3070
    • Cabannes, E.1    Khan, G.2    Aillet, F.3    Jarrett, R.F.4    Hay, R.T.5
  • 46
    • 33749078761 scopus 로고    scopus 로고
    • NF-kappaB in solid tumors
    • Pacifico, F.; Leonardi, A. NF-kappaB in solid tumors. Biochem. Pharmacol, 2006, 72(9), 1142-1152.
    • (2006) Biochem. Pharmacol , vol.72 , Issue.9 , pp. 1142-1152
    • Pacifico, F.1    Leonardi, A.2
  • 47
    • 79952272863 scopus 로고    scopus 로고
    • NFkB in T-cell acute lymphoblastic leukemia: Oncogenic functions in leukemic and in microenvironmental cells
    • Dos Santos, N. R.; Ghezzo, M. N.; R. C. Da Silva, Fernandes, M. T. NFkB in T-cell Acute Lymphoblastic Leukemia: Oncogenic Functions in Leukemic and in Microenvironmental Cells, Cancers (Basel), 2010, 2, 1838-1860.
    • (2010) Cancers (Basel) , vol.2 , pp. 1838-1860
    • Dos Santos, N.R.1    Ghezzo, M.N.2    Da Silva, R.C.3    Fernandes, M.T.4
  • 48
    • 57049183997 scopus 로고    scopus 로고
    • Recent prognostic factors in diffuse large B-cell lymphoma indicate NF-kappaB pathway as a target for new therapeutic strategies
    • Pavan, A.; Spina, M.; Canzonieri, V.; Sansonno, S.; Toffoli, G.; De Re V. Recent prognostic factors in diffuse large B-cell lymphoma indicate NF-kappaB pathway as a target for new therapeutic strategies, Leuk. Lymphoma, 2008, 49, 2048-2058.
    • (2008) Leuk. Lymphoma , vol.49 , pp. 2048-2058
    • Pavan, A.1    Spina, M.2    Canzonieri, V.3    Sansonno, S.4    Toffoli, G.5    De Re, V.6
  • 49
    • 84857389911 scopus 로고    scopus 로고
    • The c-rel transcription factor in development and disease
    • Gilmore, T. D.; Gerondakis, S.; The c-Rel Transcription Factor in Development and Disease, Genes Cancer, 2011, 2, 695-611.
    • (2011) Genes Cancer , vol.2 , pp. 695-611
    • Gilmore, T.D.1    Gerondakis, S.2
  • 51
    • 0026331456 scopus 로고
    • B cell lymphomaassociated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50
    • Neri, A.; Chang, C. C.; Lombardi, L.; Salina, M.; Corradini, P.; Maiolo, A. T.; Chaganti, R. S.; Dalla-Favera, R. B cell lymphomaassociated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50, Cell, 1991, 67, 1075-1087.
    • (1991) Cell , vol.67 , pp. 1075-1087
    • Neri, A.1    Chang, C.C.2    Lombardi, L.3    Salina, M.4    Corradini, P.5    Maiolo, A.T.6    Chaganti, R.S.7    Dalla-Favera, R.8
  • 52
    • 0026636897 scopus 로고
    • Related subunits of NF-kappa B map to two distinct loci associated with translocations in leukemia, NFKB1 and NFKB2
    • Liptay, S.; Schmid, R. M.; Perkins, N. D.; Meltzer, P.; Altherr, M. R.; McPherson, J. D.; Wasmuth, J. J.; G. J. Nabel, Related subunits of NF-kappa B map to two distinct loci associated with translocations in leukemia, NFKB1 and NFKB2, Genomics, 1992, 13, 287-292.
    • (1992) Genomics , vol.13 , pp. 287-292
    • Liptay, S.1    Schmid, R.M.2    Perkins, N.D.3    Meltzer, P.4    Altherr, M.R.5    McPherson, J.D.6    Wasmuth, J.J.7    Nabel, G.J.8
  • 54
    • 0030725774 scopus 로고    scopus 로고
    • Activation of p65 NF-kappaB protein by p210BCR-ABL in a myeloid cell line (P210BCR-ABL activates p65 NF-kappaB)
    • Hamdane, M.; David-Cordonnier, M. H.; D'Halluin, J. C. Activation of p65 NF-kappaB protein by p210BCR-ABL in a myeloid cell line (P210BCR-ABL activates p65 NF-kappaB). Oncogene, 1997, 15(19), 2267-2275.
    • (1997) Oncogene , vol.15 , Issue.19 , pp. 2267-2275
    • Hamdane, M.1    David-Cordonnier, M.H.2    D'Halluin, J.C.3
  • 55
    • 0037365086 scopus 로고    scopus 로고
    • Molecular targets in acute myelogenous leukemia
    • Stirewalt, D. L.; Meshinchi, S.; Radich, J. P. Molecular targets in acute myelogenous leukemia. Blood Rev., 2003, 17(1), 15-23.
    • (2003) Blood Rev. , vol.17 , Issue.1 , pp. 15-23
    • Stirewalt, D.L.1    Meshinchi, S.2    Radich, J.P.3
  • 58
    • 84866420065 scopus 로고    scopus 로고
    • Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer
    • Alberti, C.; Pinciroli, P.; Valeri, B.; Ferri, R.; Ditto, A.; Umezawa, K.; Sensi, M.; Canevari, S.; Tomassetti, A. Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer. Oncogene, 2012, 31(37), 4139-4149.
    • (2012) Oncogene , vol.31 , Issue.37 , pp. 4139-4149
    • Alberti, C.1    Pinciroli, P.2    Valeri, B.3    Ferri, R.4    Ditto, A.5    Umezawa, K.6    Sensi, M.7    Canevari, S.8    Tomassetti, A.9
  • 59
    • 56049094836 scopus 로고    scopus 로고
    • Increased staining for phosphorylated AKT and nuclear factorkappaB p65 and their relationship with prognosis in epithelial ovarian cancer
    • Guo, R. X.; Qiao, Y. H.; Zhou, Y.; Li, L. X.; Shi, H. R.; Chen, K. S. Increased staining for phosphorylated AKT and nuclear factorkappaB p65 and their relationship with prognosis in epithelial ovarian cancer. Pathol. Int., 2008, 58(12), 749-756.
    • (2008) Pathol. Int. , vol.58 , Issue.12 , pp. 749-756
    • Guo, R.X.1    Qiao, Y.H.2    Zhou, Y.3    Li, L.X.4    Shi, H.R.5    Chen, K.S.6
  • 61
    • 54249111455 scopus 로고    scopus 로고
    • Maintenance of constitutive IkappaB kinase activity by glycogen synthase kinase-3alpha/beta in pancreatic cancer
    • Wilson, W. 3rd; Baldwin, A. S. Maintenance of constitutive IkappaB kinase activity by glycogen synthase kinase-3alpha/beta in pancreatic cancer. Cancer Res., 2008, 68(19), 8156-8163.
    • (2008) Cancer Res. , vol.68 , Issue.19 , pp. 8156-8163
    • Wilson, W.1    Baldwin, A.S.2
  • 62
    • 0036150911 scopus 로고    scopus 로고
    • The role of IKK in constitutive activation of NF-kappaB transcription factor in prostate carcinoma cells
    • Gasparian, A. V.; Yao, Y. J.; Kowalczyk, D.; Lyakh, L. A.; Karseladze, A.; Slaga, T. J.; Budunova, I. V. The role of IKK in constitutive activation of NF-kappaB transcription factor in prostate carcinoma cells. J. Cell Sci., 2002, 115(Pt 1), 141-151.
    • (2002) J. Cell Sci. , vol.115 , pp. 141-151
    • Gasparian, A.V.1    Yao, Y.J.2    Kowalczyk, D.3    Lyakh, L.A.4    Karseladze, A.5    Slaga, T.J.6    Budunova, I.V.7
  • 63
    • 0342844268 scopus 로고    scopus 로고
    • Dynamic expression and activity of NF-kappaB during post-natal mammary gland morphogenesis
    • Brantley, D. M.; Yull, F. E.; Muraoka, R. S.; Hicks, D. J.; Cook, C. M.; Kerr, L. D. Dynamic expression and activity of NF-kappaB during post-natal mammary gland morphogenesis. Mech. Dev., 2000, 97(1-2), 149-155.
    • (2000) Mech. Dev. , vol.97 , Issue.1-2 , pp. 149-155
    • Brantley, D.M.1    Yull, F.E.2    Muraoka, R.S.3    Hicks, D.J.4    Cook, C.M.5    Kerr, L.D.6
  • 65
    • 0034708132 scopus 로고    scopus 로고
    • Selective activation of NF-kappa B subunits in human breast cancer: Potential roles for NF-kappa B2/p52 and for Bcl-3
    • Cogswell, P. C.; Guttridge, D. C.; Funkhouser, W. K.; Baldwin, A. S., Jr. Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3. Oncogene, 2000, 19(9), 1123-1131.
    • (2000) Oncogene , vol.19 , Issue.9 , pp. 1123-1131
    • Cogswell, P.C.1    Guttridge, D.C.2    Funkhouser, W.K.3    Baldwin, A.S.4
  • 66
    • 0030927167 scopus 로고    scopus 로고
    • Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth
    • Nakshatri, H.; Bhat-Nakshatri, P.; Martin, D. A.; Goulet, R. J., Jr.; Sledge, G. W., Jr. Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth. Mol. Cell Biol., 1997, 17(7), 3629-3639.
    • (1997) Mol. Cell Biol. , vol.17 , Issue.7 , pp. 3629-3639
    • Nakshatri, H.1    Bhat-Nakshatri, P.2    Martin, D.A.3    Goulet, R.J.4    Sledge, G.W.5
  • 68
    • 27644494143 scopus 로고    scopus 로고
    • RelB/p52 NF-kappaB complexes rescue an early delay in mammary gland development in transgenic mice with targeted superrepressor IkappaB-alpha expression and promote carcinogenesis of the mammary gland
    • Demicco, E. G.; Kavanagh, K. T.; Romieu-Mourez, R.; Wang, X.; Shin, S. R.; Landesman-Bollag, E.; Seldin, D. C; Sonenshein, G. E. RelB/p52 NF-kappaB complexes rescue an early delay in mammary gland development in transgenic mice with targeted superrepressor IkappaB-alpha expression and promote carcinogenesis of the mammary gland. Mol. Cell Biol, 2005, 25(22), 10136-10147.
    • (2005) Mol. Cell Biol , vol.25 , Issue.22 , pp. 10136-10147
    • Demicco, E.G.1    Kavanagh, K.T.2    Romieu-Mourez, R.3    Wang, X.4    Shin, S.R.5    Landesman-Bollag, E.6    Seldin, D.C.7    Sonenshein, G.E.8
  • 69
    • 0242495765 scopus 로고    scopus 로고
    • Receptor activator of NF-kappaB ligand induction via Jak2 and Stat5a in mammary epithelial cells
    • Srivastava, S.; Matsuda, M.; Hou, Z.; Bailey, J. P.; Kitazawa, R.; Herbst, M. P.; Horseman, N. D. Receptor activator of NF-kappaB ligand induction via Jak2 and Stat5a in mammary epithelial cells. J. Biol. Chem., 2003, 278(46), 46171-46178.
    • (2003) J. Biol. Chem. , vol.278 , Issue.46 , pp. 46171-46178
    • Srivastava, S.1    Matsuda, M.2    Hou, Z.3    Bailey, J.P.4    Kitazawa, R.5    Herbst, M.P.6    Horseman, N.D.7
  • 70
    • 33745213966 scopus 로고    scopus 로고
    • Nuclear factor-kappaB signature of inflammatory breast cancer by cDNA microarray validated by quantitative real-time reverse transcription-PCR, immunohistochemistry, and nuclear factor-kappaB DNA-binding
    • Van Laere, S. J.; Van Der Auwera, I.; Van Den Eynden, G. G.; Elst, H. J.; Weyler, J.; Harris, A. L.; Van Dam, P.; Van Marck, E. A.; Vermeulen, P. B.; Dirix, L. Y. Nuclear factor-kappaB signature of inflammatory breast cancer by cDNA microarray validated by quantitative real-time reverse transcription-PCR, immunohistochemistry, and nuclear factor-kappaB DNA-binding. Clin. Cancer Res., 2006, 12(11 Pt 1), 3249-3256.
    • (2006) Clin. Cancer Res. , vol.12 , Issue.11 , pp. 3249-3256
    • Van Laere, S.J.1    Van Der Auwera, I.2    Van Den Eynden, G.G.3    Elst, H.J.4    Weyler, J.5    Harris, A.L.6    Van Dam, P.7    Van Marck, E.A.8    Vermeulen, P.B.9    Dirix, L.Y.10
  • 71
    • 34548299550 scopus 로고    scopus 로고
    • NF-kappaB activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivation
    • Van Laere, S. J.; Van Der Auwera, I.; Van Den Eynden, G. G.; Van Dam, P.; Van Marck, E. A.; Vermeulen, P. B.; Dirix, L. Y. NF-kappaB activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivation. Br. J. Cancer, 2007, 97(5), 659-669.
    • (2007) Br. J. Cancer , vol.97 , Issue.5 , pp. 659-669
    • Van Laere, S.J.1    Van Der Auwera, I.2    Van Den Eynden, G.G.3    Van Dam, P.4    Van Marck, E.A.5    Vermeulen, P.B.6    Dirix, L.Y.7
  • 73
    • 84860864158 scopus 로고    scopus 로고
    • NF-kappaB, stem cells and breast cancer: The links get stronger
    • Shostak, K.; Chariot, A. NF-kappaB, stem cells and breast cancer: the links get stronger. Breast Cancer Res., 2011, 13(4), 214.
    • (2011) Breast Cancer Res. , vol.13 , Issue.4 , pp. 214
    • Shostak, K.1    Chariot, A.2
  • 74
    • 84864626251 scopus 로고    scopus 로고
    • Radiation-triggered NF-kappaB activation is responsible for the angiogenic signaling pathway and neovascularization for breast cancer cell proliferation and growth
    • Yu, H.; Mohan, S.; Natarajan, M. Radiation-Triggered NF-kappaB Activation is Responsible for the Angiogenic Signaling Pathway and Neovascularization for Breast Cancer Cell Proliferation and Growth. Breast Cancer Res., 2012, 6, 125-135.
    • (2012) Breast Cancer Res. , vol.6 , pp. 125-135
    • Yu, H.1    Mohan, S.2    Natarajan, M.3
  • 76
    • 77954428063 scopus 로고    scopus 로고
    • ROS-NFkappaB mediates TGF-beta1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion
    • Tobar, N.; Villar, V.; Santibanez, J. F. ROS-NFkappaB mediates TGF-beta1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion. Mol. Cell Biochem., 2010, 340(1-2), 195-202.
    • (2010) Mol. Cell Biochem. , vol.340 , Issue.1-2 , pp. 195-202
    • Tobar, N.1    Villar, V.2    Santibanez, J.F.3
  • 77
    • 77953496625 scopus 로고    scopus 로고
    • The NF-kappaB family of transcription factors and its regulation
    • Oeckinghaus, A.; Ghosh, S. The NF-kappaB family of transcription factors and its regulation. Cold Spring Harb. Perspect. Biol, 2009, 1(4), a000034.
    • (2009) Cold Spring Harb. Perspect. Biol , vol.1 , Issue.4 , pp. a000034
    • Oeckinghaus, A.1    Ghosh, S.2
  • 78
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl, H. L. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene, 1999, 18(49), 6853-6866.
    • (1999) Oncogene , vol.18 , Issue.49 , pp. 6853-6866
    • Pahl, H.L.1
  • 79
    • 84891486850 scopus 로고    scopus 로고
    • A20-mediated negative regulation of canonical NF-kB signaling pathway
    • Pujari, R.; Hunte, R.; Khan, W. N.; Shembade, N. A20-mediated negative regulation of canonical NF-kB signaling pathway. Immunol. Res., 2013, 57(1-3), 166-171.
    • (2013) Immunol. Res. , vol.57 , Issue.1-3 , pp. 166-171
    • Pujari, R.1    Hunte, R.2    Khan, W.N.3    Shembade, N.4
  • 80
    • 78650920066 scopus 로고    scopus 로고
    • Non-canonical NF-kappaB signaling pathway
    • Sun, S. C. Non-canonical NF-kappaB signaling pathway. Cell Res., 2011, 21(1), 71-85.
    • (2011) Cell Res. , vol.21 , Issue.1 , pp. 71-85
    • Sun, S.C.1
  • 81
    • 80054854922 scopus 로고    scopus 로고
    • Non-canonical NF-kappaB signaling activation and regulation: Principles and perspectives
    • Razani, B.; Reichardt, A. D.; Cheng, G. Non-canonical NF-kappaB signaling activation and regulation: principles and perspectives. Immunol. Rev., 2011, 244(1), 44-54.
    • (2011) Immunol. Rev. , vol.244 , Issue.1 , pp. 44-54
    • Razani, B.1    Reichardt, A.D.2    Cheng, G.3
  • 82
    • 84895930567 scopus 로고    scopus 로고
    • Canonical and non-canonical NF-kappaB signaling promotes breast cancer tumor-initiating cells
    • Kendellen, M. F.; Bradford, J. W.; Lawrence, C. L.; Clark, K. S.; Baldwin, A. S. Canonical and non-canonical NF-kappaB signaling promotes breast cancer tumor-initiating cells. Oncogene, 2014, 33(10), 1297-1305.
    • (2014) Oncogene , vol.33 , Issue.10 , pp. 1297-1305
    • Kendellen, M.F.1    Bradford, J.W.2    Lawrence, C.L.3    Clark, K.S.4    Baldwin, A.S.5
  • 83
    • 0344305376 scopus 로고    scopus 로고
    • Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress
    • Huang, T. T.; Wuerzberger-Davis, S. M.; Wu, Z. H.; Miyamoto, S. Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. Cell, 2003, 115(5), 565-576.
    • (2003) Cell , vol.115 , Issue.5 , pp. 565-576
    • Huang, T.T.1    Wuerzberger-Davis, S.M.2    Wu, Z.H.3    Miyamoto, S.4
  • 84
    • 0242298578 scopus 로고    scopus 로고
    • CK2 Is a C-terminal IkappaB kinase responsible for NF-kappaB activation during the UV response
    • Kato, T., Jr.; Delhase, M.; Hoffmann, A.; Karin, M. CK2 Is a C-Terminal IkappaB Kinase Responsible for NF-kappaB Activation during the UV Response. Mol. Cell, 2003, 12(4), 829-839.
    • (2003) Mol. Cell , vol.12 , Issue.4 , pp. 829-839
    • Kato, T.1    Delhase, M.2    Hoffmann, A.3    Karin, M.4
  • 85
    • 0242664121 scopus 로고    scopus 로고
    • IkappaB kinase-independent IkappaBalpha degradation pathway: Functional NF-kappaB activity and implications for cancer therapy
    • Tergaonkar, V.; Bottero, V.; Ikawa, M.; Li, Q.; Verma, I. M. IkappaB kinase-independent IkappaBalpha degradation pathway: functional NF-kappaB activity and implications for cancer therapy. Mol. Cell Biol., 2003, 23(22), 8070-8083.
    • (2003) Mol. Cell Biol. , vol.23 , Issue.22 , pp. 8070-8083
    • Tergaonkar, V.1    Bottero, V.2    Ikawa, M.3    Li, Q.4    Verma, I.M.5
  • 87
    • 77953693097 scopus 로고    scopus 로고
    • Posttranslational modifications of NF-kappaB: Another layer of regulation for NF-kappaB signaling pathway
    • Huang, B.; Yang, X. D.; Lamb, A.; Chen, L. F. Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway. Cell Signal., 2010, 22(9), 1282-1290.
    • (2010) Cell Signal. , vol.22 , Issue.9 , pp. 1282-1290
    • Huang, B.1    Yang, X.D.2    Lamb, A.3    Chen, L.F.4
  • 88
    • 33845207648 scopus 로고    scopus 로고
    • Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis
    • Liu, Y.; Smith, P. W.; Jones, D. R. Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis. Mol. Cell Biol., 2006, 26(23), 8683-8696.
    • (2006) Mol. Cell Biol. , vol.26 , Issue.23 , pp. 8683-8696
    • Liu, Y.1    Smith, P.W.2    Jones, D.R.3
  • 89
    • 84865120393 scopus 로고    scopus 로고
    • NFkappaB signaling is important for growth of antiestrogen resistant breast cancer cells
    • Yde, C. W.; Emdal, K. B.; Guerra, B.; Lykkesfeldt, A. E. NFkappaB signaling is important for growth of antiestrogen resistant breast cancer cells. Breast Cancer Res. Treat., 2012, 135(1), 67-78.
    • (2012) Breast Cancer Res. Treat. , vol.135 , Issue.1 , pp. 67-78
    • Yde, C.W.1    Emdal, K.B.2    Guerra, B.3    Lykkesfeldt, A.E.4
  • 90
    • 33750457370 scopus 로고    scopus 로고
    • Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway
    • Perkins, N. D. Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway. Oncogene, 2006, 25(51), 6717-6730.
    • (2006) Oncogene , vol.25 , Issue.51 , pp. 6717-6730
    • Perkins, N.D.1
  • 91
    • 33750301637 scopus 로고    scopus 로고
    • Unraveling androgen receptor interactomes by an array-based method: Discovery of proto-oncoprotein c-Rel as a negative regulator of androgen receptor
    • Mukhopadhyay, N. K.; Ferdinand, A. S.; Mukhopadhyay, L.; Cinar, B.; Lutchman, M.; Richie, J. P.; Freeman, M. R.; Liu, B. C. Unraveling androgen receptor interactomes by an array-based method: discovery of proto-oncoprotein c-Rel as a negative regulator of androgen receptor. Exp. Cell Res., 2006, 312(19), 3782-3795.
    • (2006) Exp. Cell Res. , vol.312 , Issue.19 , pp. 3782-3795
    • Mukhopadhyay, N.K.1    Ferdinand, A.S.2    Mukhopadhyay, L.3    Cinar, B.4    Lutchman, M.5    Richie, J.P.6    Freeman, M.R.7    Liu, B.C.8
  • 92
    • 36849010739 scopus 로고    scopus 로고
    • RelB, a new partner of aryl hydrocarbon receptormediated transcription
    • Vogel, C. F.; Sciullo, E.; Li, W.; Wong, P.; Lazennec, G.; Matsumura, F. RelB, a new partner of aryl hydrocarbon receptormediated transcription. Mol. Endocrinol., 2007, 21(12), 2941-2955.
    • (2007) Mol. Endocrinol. , vol.21 , Issue.12 , pp. 2941-2955
    • Vogel, C.F.1    Sciullo, E.2    Li, W.3    Wong, P.4    Lazennec, G.5    Matsumura, F.6
  • 93
    • 2342510314 scopus 로고    scopus 로고
    • Identification of beta-arrestin2 as a G protein-coupled receptorstimulated regulator of NF-kappaB pathways
    • Gao, H.; Sun, Y.; Wu, Y.; Luan, B.; Wang, Y.; Qu, B.; Pei, G. Identification of beta-arrestin2 as a G protein-coupled receptorstimulated regulator of NF-kappaB pathways. Mol. Cell, 2004, 14(3), 303-317.
    • (2004) Mol. Cell , vol.14 , Issue.3 , pp. 303-317
    • Gao, H.1    Sun, Y.2    Wu, Y.3    Luan, B.4    Wang, Y.5    Qu, B.6    Pei, G.7
  • 94
    • 33845960758 scopus 로고    scopus 로고
    • Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages
    • Parameswaran, N.; Pao, C. S.; Leonhard, K. S.; Kang, D. S.; Kratz, M.; Ley, S. C.; Benovic, J. L. Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages. J. Biol. Chem., 2006, 281(45), 34159-34170.
    • (2006) J. Biol. Chem. , vol.281 , Issue.45 , pp. 34159-34170
    • Parameswaran, N.1    Pao, C.S.2    Leonhard, K.S.3    Kang, D.S.4    Kratz, M.5    Ley, S.C.6    Benovic, J.L.7
  • 96
    • 32644453624 scopus 로고    scopus 로고
    • Hydrogen peroxide inhibits IL-12 p40 induction in macrophages by inhibiting c-rel translocation to the nucleus through activation of calmodulin protein
    • Khan, N.; Rahim, S. S.; Boddupalli, C. S.; Ghousunnissa, S.; Padma, S.; Pathak, N.; Thiagarajan, D.; Hasnain, S. E.; Mukhopadhyay, S. Hydrogen peroxide inhibits IL-12 p40 induction in macrophages by inhibiting c-rel translocation to the nucleus through activation of calmodulin protein. Blood, 2006, 107(4), 1513-1520.
    • (2006) Blood , vol.107 , Issue.4 , pp. 1513-1520
    • Khan, N.1    Rahim, S.S.2    Boddupalli, C.S.3    Ghousunnissa, S.4    Padma, S.5    Pathak, N.6    Thiagarajan, D.7    Hasnain, S.E.8    Mukhopadhyay, S.9
  • 97
    • 0032575565 scopus 로고    scopus 로고
    • Association of Cdk2/cyclin E and NF-kappa B complexes at G1/S phase
    • Chen, E.; Li, C. C. Association of Cdk2/cyclin E and NF-kappa B complexes at G1/S phase. Biochem. Biophys. Res. Comm., 1998, 249(3), 728-734.
    • (1998) Biochem. Biophys. Res. Comm. , vol.249 , Issue.3 , pp. 728-734
    • Chen, E.1    Li, C.C.2
  • 98
    • 0027224017 scopus 로고
    • Cross-coupling of the NF-kappa B p65 and Fos/Jun. Transcription factors produces potentiated biological function
    • Stein, B.; Baldwin, A. S., Jr.; Ballard, D. W.; Greene, W. C.; Angel, P.; Herrlich, P. Cross-coupling of the NF-kappa B p65 and Fos/Jun. transcription factors produces potentiated biological function. EMBO J., 1993, 12(10), 3879-3891.
    • (1993) EMBO J. , vol.12 , Issue.10 , pp. 3879-3891
    • Stein, B.1    Baldwin, A.S.2    Ballard, D.W.3    Greene, W.C.4    Angel, P.5    Herrlich, P.6
  • 99
    • 39949085247 scopus 로고    scopus 로고
    • IKK gamma (NEMO) is involved in the coordination of the AP-1 and NF-kappa B pathways
    • Shifera, A. S.; Friedman, J. M.; Horwitz, M. S. IKK gamma (NEMO) is involved in the coordination of the AP-1 and NF-kappa B pathways. Mol. Cell Biol., 2008, 310(1-2), 181-190.
    • (2008) Mol. Cell Biol. , vol.310 , Issue.1-2 , pp. 181-190
    • Shifera, A.S.1    Friedman, J.M.2    Horwitz, M.S.3
  • 100
    • 0034693133 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II
    • Wang, D.; Westerheide, S. D.; Hanson, J. L.; Baldwin, A. S., Jr. Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II. J. Biol. Chem., 2000, 275(42), 32592-32597.
    • (2000) J. Biol. Chem. , vol.275 , Issue.42 , pp. 32592-32597
    • Wang, D.1    Westerheide, S.D.2    Hanson, J.L.3    Baldwin, A.S.4
  • 104
    • 80052222327 scopus 로고    scopus 로고
    • Context-specific regulation of NF-kappaB target gene expression by EZH2 in breast cancers
    • Lee, S. T.; Li, Z.; Wu, Z.; Aau, M.; Guan, P.; Karuturi, R. K.; Liou, Y. C.; Yu, Q. Context-specific regulation of NF-kappaB target gene expression by EZH2 in breast cancers. Mol. Cell, 2011, 43(5), 798-810.
    • (2011) Mol. Cell , vol.43 , Issue.5 , pp. 798-810
    • Lee, S.T.1    Li, Z.2    Wu, Z.3    Aau, M.4    Guan, P.5    Karuturi, R.K.6    Liou, Y.C.7    Yu, Q.8
  • 105
    • 34347333594 scopus 로고    scopus 로고
    • Direct interaction between estrogen receptor alpha and NF-kappaB in the nucleus of living cells
    • Quaedackers, M. E.; Van Den Brink, C. E.; Van Der Saag, P. T.; Tertoolen, L. G. Direct interaction between estrogen receptor alpha and NF-kappaB in the nucleus of living cells. Mol. Cell Endocrinol., 2007, 273(1-2), 42-50.
    • (2007) Mol. Cell Endocrinol. , vol.273 , Issue.1-2 , pp. 42-50
    • Quaedackers, M.E.1    Van Den Brink, C.E.2    Van Der Saag, P.T.3    Tertoolen, L.G.4
  • 106
    • 33947613012 scopus 로고    scopus 로고
    • Identification of proteins within the nuclear factorkappa B transcriptional complex including estrogen receptor-alpha
    • discussion 394 e11-3
    • Feldman, I.; Feldman, G. M.; Mobarak, C.; Dunkelberg, J. C.; Leslie, K. K. Identification of proteins within the nuclear factorkappa B transcriptional complex including estrogen receptor-alpha. Am. J. Obstet. Gynecol., 2007, 196(4), 394 e1-11; discussion 394 e11-3.
    • (2007) Am. J. Obstet. Gynecol. , vol.196 , Issue.4 , pp. 394e1-394e11
    • Feldman, I.1    Feldman, G.M.2    Mobarak, C.3    Dunkelberg, J.C.4    Leslie, K.K.5
  • 107
    • 13944252475 scopus 로고    scopus 로고
    • Transcription factor cross-talk: The estrogen receptor and NF-kappaB
    • Kalaitzidis, D.; Gilmore, T. D. Transcription factor cross-talk: the estrogen receptor and NF-kappaB. Trend Endocrinol. Metabol., 2005, 16(2), 46-52.
    • (2005) Trend Endocrinol. Metabol. , vol.16 , Issue.2 , pp. 46-52
    • Kalaitzidis, D.1    Gilmore, T.D.2
  • 109
    • 33748754549 scopus 로고    scopus 로고
    • Suppression of NF-kappaB activation by Entamoeba histolytica in intestinal epithelial cells is mediated by heat shock protein 27
    • Kammanadiminti, S. J.; Chadee, K. Suppression of NF-kappaB activation by Entamoeba histolytica in intestinal epithelial cells is mediated by heat shock protein 27. J. Biol. Chem., 2006, 281(36), 26112-26120.
    • (2006) J. Biol. Chem. , vol.281 , Issue.36 , pp. 26112-26120
    • Kammanadiminti, S.J.1    Chadee, K.2
  • 110
    • 0034802887 scopus 로고    scopus 로고
    • The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
    • Ashburner, B. P.; Westerheide, S. D.; Baldwin, A. S., Jr. The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol. Cell Biol., 2001, 21(20), 7065-7077.
    • (2001) Mol. Cell Biol. , vol.21 , Issue.20 , pp. 7065-7077
    • Ashburner, B.P.1    Westerheide, S.D.2    Baldwin, A.S.3
  • 111
    • 0344012547 scopus 로고    scopus 로고
    • Cytoplasmic IkappaBalpha increases NF-kappaB-independent transcription through binding to histone deacetylase (HDAC) 1 and HDAC3
    • Viatour, P.; Legrand-Poels, S.; Van Lint, C.; Warnier, M.; Merville, M. P.; Gielen, J.; Piette, J.; Bours, V.; Chariot, A. Cytoplasmic IkappaBalpha increases NF-kappaB-independent transcription through binding to histone deacetylase (HDAC) 1 and HDAC3. J. Biol. Chem., 2003, 278(47), 46541-46548.
    • (2003) J. Biol. Chem. , vol.278 , Issue.47 , pp. 46541-46548
    • Viatour, P.1    Legrand-Poels, S.2    Van Lint, C.3    Warnier, M.4    Merville, M.P.5    Gielen, J.6    Piette, J.7    Bours, V.8    Chariot, A.9
  • 112
    • 0035979737 scopus 로고    scopus 로고
    • Duration of nuclear NF-kappaB action regulated by reversible acetylation
    • Chen, L.; Fischle, W.; Verdin, E.; Greene, W. C. Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science, 2001, 293(5535), 1653-1657.
    • (2001) Science , vol.293 , Issue.5535 , pp. 1653-1657
    • Chen, L.1    Fischle, W.2    Verdin, E.3    Greene, W.C.4
  • 114
    • 0029879315 scopus 로고    scopus 로고
    • Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation
    • Meyer, C. F.; Wang, X.; Chang, C.; Templeton, D.; Tan, T. H. Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation. J. Biol. Chem., 1996, 271(15), 8971-8976.
    • (1996) J. Biol. Chem. , vol.271 , Issue.15 , pp. 8971-8976
    • Meyer, C.F.1    Wang, X.2    Chang, C.3    Templeton, D.4    Tan, T.H.5
  • 115
    • 44849117768 scopus 로고    scopus 로고
    • Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK
    • Dan, H. C.; Cooper, M. J.; Cogswell, P. C.; Duncan, J. A.; Ting, J. P.; Baldwin, A. S. Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK. Genes Dev., 2008, 22(11), 1490-1500.
    • (2008) Genes Dev. , vol.22 , Issue.11 , pp. 1490-1500
    • Dan, H.C.1    Cooper, M.J.2    Cogswell, P.C.3    Duncan, J.A.4    Ting, J.P.5    Baldwin, A.S.6
  • 116
    • 28444491798 scopus 로고    scopus 로고
    • Constitutive NF-kappaB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival
    • Pham, L. V.; Tamayo, A. T.; Yoshimura, L. C.; Lin-Lee, Y. C.; Ford, R. J. Constitutive NF-kappaB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival. Blood, 2005, 106(12), 3940-3947.
    • (2005) Blood , vol.106 , Issue.12 , pp. 3940-3947
    • Pham, L.V.1    Tamayo, A.T.2    Yoshimura, L.C.3    Lin-Lee, Y.C.4    Ford, R.J.5
  • 118
    • 21144452459 scopus 로고    scopus 로고
    • Involvement of poly (ADP-ribose) polymerase 1 in ERBB2 expression in rheumatoid synovial cells
    • Kitamura, T.; Sekimata, M.; Kikuchi, S.; Homma, Y. Involvement of poly (ADP-ribose) polymerase 1 in ERBB2 expression in rheumatoid synovial cells. Am. J. Physiol. Cell Physiol., 2005, 289(1), C82-88.
    • (2005) Am. J. Physiol. Cell Physiol. , vol.289 , Issue.1 , pp. C82-C88
    • Kitamura, T.1    Sekimata, M.2    Kikuchi, S.3    Homma, Y.4
  • 119
    • 0029939162 scopus 로고    scopus 로고
    • Negative interaction between the RelA (p65) subunit of NF-kappaB and the progesterone receptor
    • Kalkhoven, E.; Wissink, S.; Van Der Saag, P. T.; Van Der Burg, B. Negative interaction between the RelA (p65) subunit of NF-kappaB and the progesterone receptor. J. Biol. Chem., 1996, 271(11), 6217-6224.
    • (1996) J. Biol. Chem. , vol.271 , Issue.11 , pp. 6217-6224
    • Kalkhoven, E.1    Wissink, S.2    Van Der Saag, P.T.3    Van Der Burg, B.4
  • 120
    • 0033570917 scopus 로고    scopus 로고
    • Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB
    • Nourbakhsh, M.; Hauser, H. Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB. EMBO J., 1999, 18(22), 6415-6425.
    • (1999) EMBO J. , vol.18 , Issue.22 , pp. 6415-6425
    • Nourbakhsh, M.1    Hauser, H.2
  • 121
    • 0038146926 scopus 로고    scopus 로고
    • Promyelocytic leukemia protein sensitizes tumor necrosis factor alpha-induced apoptosis by inhibiting the NF-kappaB survival pathway
    • Wu, W. S.; Xu, Z. X.; Hittelman, W. N.; Salomoni, P.; Pandolfi, P. P.; Chang, K. S. Promyelocytic leukemia protein sensitizes tumor necrosis factor alpha-induced apoptosis by inhibiting the NF-kappaB survival pathway. J. Biol. Chem., 2003, 278(14), 12294-12304.
    • (2003) J. Biol. Chem. , vol.278 , Issue.14 , pp. 12294-12304
    • Wu, W.S.1    Xu, Z.X.2    Hittelman, W.N.3    Salomoni, P.4    Pandolfi, P.P.5    Chang, K.S.6
  • 123
    • 0037155893 scopus 로고    scopus 로고
    • The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression
    • Chang, N. S. The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression. J. Biol. Chem., 2002, 277(12), 10323-10331.
    • (2002) J. Biol. Chem. , vol.277 , Issue.12 , pp. 10323-10331
    • Chang, N.S.1
  • 127
    • 0036797750 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB
    • Yu, Z.; Zhang, W.; Kone, B. C. Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB. Biochem J., 2002, 367(Pt 1), 97-105.
    • (2002) Biochem J. , vol.367 , pp. 97-105
    • Yu, Z.1    Zhang, W.2    Kone, B.C.3
  • 128
    • 0345826123 scopus 로고    scopus 로고
    • Interleukin 1 activates STAT3/nuclear factorkappaB cross-talk via a unique TRAF6- and p65-dependent mechanism
    • Yoshida, Y.; Kumar, A.; Koyama, Y.; Peng, H.; Arman, A.; Boch, J. A.; Auron, P. E. Interleukin 1 activates STAT3/nuclear factorkappaB cross-talk via a unique TRAF6- and p65-dependent mechanism. J. Biol. Chem., 2004, 279(3), 1768-1776.
    • (2004) J. Biol. Chem. , vol.279 , Issue.3 , pp. 1768-1776
    • Yoshida, Y.1    Kumar, A.2    Koyama, Y.3    Peng, H.4    Arman, A.5    Boch, J.A.6    Auron, P.E.7
  • 129
    • 84893530696 scopus 로고    scopus 로고
    • Constitutive activation of STAT3 signaling regulates hTERT and promotes stem cell-like traits in human breast cancer cells
    • Chung, S. S.; Aroh, C.; Vadgama, J. V. Constitutive activation of STAT3 signaling regulates hTERT and promotes stem cell-like traits in human breast cancer cells. PloS one, 2013, 8(12), e83971.
    • (2013) PloS One , vol.8 , Issue.12 , pp. e83971
    • Chung, S.S.1    Aroh, C.2    Vadgama, J.V.3
  • 131
    • 84891804538 scopus 로고    scopus 로고
    • Oestrogen receptors in breast cancer: Basic mechanisms and clinical implications
    • Williams, C.; Lin, C. Y. Oestrogen receptors in breast cancer: basic mechanisms and clinical implications. Ecancermedicalscience, 2013, 7, 370.
    • (2013) Ecancermedicalscience , vol.7 , pp. 370
    • Williams, C.1    Lin, C.Y.2
  • 132
    • 84871432401 scopus 로고    scopus 로고
    • Estrogen receptor-dependent and independent mechanisms of breast cancer carcinogenesis
    • Yue, W.; Yager, J. D.; Wang, J. P.; Jupe, E. R.; Santen, R. J. Estrogen receptor-dependent and independent mechanisms of breast cancer carcinogenesis. Steroids, 2013, 78(2), 161-170.
    • (2013) Steroids , vol.78 , Issue.2 , pp. 161-170
    • Yue, W.1    Yager, J.D.2    Wang, J.P.3    Jupe, E.R.4    Santen, R.J.5
  • 133
    • 30944469849 scopus 로고    scopus 로고
    • Estrogen carcinogenesis in breast cancer
    • Yager, J. D.; Davidson, N. E. Estrogen carcinogenesis in breast cancer. N. Eng. J. Med., 2006, 354(3), 270-282.
    • (2006) N. Eng. J. Med. , vol.354 , Issue.3 , pp. 270-282
    • Yager, J.D.1    Davidson, N.E.2
  • 134
    • 0141864377 scopus 로고    scopus 로고
    • Apoptosis, chemoresistance, and breast cancer: Insights from the MCF-7 cell model system
    • Simstein, R.; Burow, M.; Parker, A.; Weldon, C.; Beckman, B. Apoptosis, chemoresistance, and breast cancer: insights from the MCF-7 cell model system. Exp. Biol. Med. (Maywood), 2003, 228(9), 995-1003.
    • (2003) Exp. Biol. Med. (Maywood) , vol.228 , Issue.9 , pp. 995-1003
    • Simstein, R.1    Burow, M.2    Parker, A.3    Weldon, C.4    Beckman, B.5
  • 135
    • 84880272602 scopus 로고    scopus 로고
    • Sex hormone receptors in breast cancer
    • D'Abreo, N.; Hindenburg, A. A. Sex hormone receptors in breast cancer. Vitam. Horm., 2013, 93, 99-133.
    • (2013) Vitam. Horm. , vol.93 , pp. 99-133
    • D'Abreo, N.1    Hindenburg, A.A.2
  • 137
    • 1342332354 scopus 로고    scopus 로고
    • Inflammatory breast carcinoma: The sphinx of breast cancer research
    • author reply 383
    • Cristofanilli, M.; Singletary, E. S.; Hortobagyi, G. N. Inflammatory breast carcinoma: the sphinx of breast cancer research. J. Clin. Oncol., 2004, 22(2), 381-383; author reply 383.
    • (2004) J. Clin. Oncol. , vol.22 , Issue.2 , pp. 381-383
    • Cristofanilli, M.1    Singletary, E.S.2    Hortobagyi, G.N.3
  • 138
    • 84865742349 scopus 로고    scopus 로고
    • Molecular basis of triple negative breast cancer and implications for therapy
    • Peddi, P. F.; Ellis, M. J.; Ma, C. Molecular basis of triple negative breast cancer and implications for therapy. Int. J. Breast Cancer, 2012, 2012, 217185.
    • (2012) Int. J. Breast Cancer , vol.2012 , pp. 217185
    • Peddi, P.F.1    Ellis, M.J.2    Ma, C.3
  • 140
  • 141
    • 0037659646 scopus 로고    scopus 로고
    • The Re1/NF-kappa B/I kappa B signal transduction pathway and cancer
    • Gilmore, T. D. The Re1/NF-kappa B/I kappa B signal transduction pathway and cancer. Cancer Treat. Res., 2003, 115, 241-265.
    • (2003) Cancer Treat. Res. , vol.115 , pp. 241-265
    • Gilmore, T.D.1
  • 142
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
    • Baldwin, A. S. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J. Clin. Invest., 2001, 107(3), 241-246.
    • (2001) J. Clin. Invest. , vol.107 , Issue.3 , pp. 241-246
    • Baldwin, A.S.1
  • 143
    • 84875810173 scopus 로고    scopus 로고
    • IKKepsilon-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex
    • Zhou, A. Y.; Shen, R. R.; Kim, E.; Lock, Y. J.; Xu, M.; Chen, Z. J.; Hahn, W. C. IKKepsilon-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex. Cell Rep., 2013, 3(3), 724-733.
    • (2013) Cell Rep. , vol.3 , Issue.3 , pp. 724-733
    • Zhou, A.Y.1    Shen, R.R.2    Kim, E.3    Lock, Y.J.4    Xu, M.5    Chen, Z.J.6    Hahn, W.C.7
  • 144
    • 79951517699 scopus 로고    scopus 로고
    • Emerging roles for the non-canonical IKKs in cancer
    • Shen, R. R.; Hahn, W. C. Emerging roles for the non-canonical IKKs in cancer. Oncogene, 2011, 30(6), 631-641.
    • (2011) Oncogene , vol.30 , Issue.6 , pp. 631-641
    • Shen, R.R.1    Hahn, W.C.2
  • 145
    • 63149160727 scopus 로고    scopus 로고
    • Regulation of macrophage function in tumors: The multifaceted role of NF-kappaB
    • Hagemann, T.; Biswas, S. K.; Lawrence, T.; Sica, A.; Lewis, C. E. Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB. Blood, 2009, 113(14), 3139-3146.
    • (2009) Blood , vol.113 , Issue.14 , pp. 3139-3146
    • Hagemann, T.1    Biswas, S.K.2    Lawrence, T.3    Sica, A.4    Lewis, C.E.5
  • 146
    • 33646755569 scopus 로고    scopus 로고
    • Cancer immunosurveillance and immunoediting: The roles of immunity in suppressing tumor development and shaping tumor immunogenicity
    • Smyth, M. J.; Dunn, G. P.; Schreiber, R. D. Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity. Adv. Immunol, 2006, 90, 1-50.
    • (2006) Adv. Immunol , vol.90 , pp. 1-50
    • Smyth, M.J.1    Dunn, G.P.2    Schreiber, R.D.3
  • 148
    • 40349094954 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Balancing immune response: Crosstalk between adaptive and innate immune cells during breast cancer progression
    • De Nardo, D. G.; Coussens, L. M. Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Res., 2007, 9(4), 212.
    • (2007) Breast Cancer Res. , vol.9 , Issue.4 , pp. 212
    • De Nardo, D.G.1    Coussens, L.M.2
  • 150
    • 0029134905 scopus 로고
    • Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation
    • Stewart, T.; Tsai, S. C; Grayson, H.; Henderson, R.; Opelz, G. Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation. Lancet, 1995, 346(8978), 796-798.
    • (1995) Lancet , vol.346 , Issue.8978 , pp. 796-798
    • Stewart, T.1    Tsai, S.C.2    Grayson, H.3    Henderson, R.4    Opelz, G.5
  • 151
    • 78650555076 scopus 로고    scopus 로고
    • Estrogen-induced reactive oxygen species-mediated signalings contribute to breast cancer
    • Okoh, V.; Deoraj, A.; Roy, D. Estrogen-induced reactive oxygen species-mediated signalings contribute to breast cancer. Biochim. Biophys. Acta, 2011, 1815(1), 115-133.
    • (2011) Biochim. Biophys. Acta , vol.1815 , Issue.1 , pp. 115-133
    • Okoh, V.1    Deoraj, A.2    Roy, D.3
  • 152
    • 0032588170 scopus 로고    scopus 로고
    • NF-kappaB function in growth control: Regulation of cyclin D1 expression and G0/G1-to-S-phase transition
    • Hinz, M.; Krappmann, D.; Eichten, A.; Heder, A.; Scheidereit, C; Strauss, M. NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition. Mol Cell Biol, 1999, 19(4), 2690-2698.
    • (1999) Mol Cell Biol , vol.19 , Issue.4 , pp. 2690-2698
    • Hinz, M.1    Krappmann, D.2    Eichten, A.3    Heder, A.4    Scheidereit, C.5    Strauss, M.6
  • 153
    • 0030614504 scopus 로고    scopus 로고
    • Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
    • Perkins, N. D.; Felzien, L. K.; Betts, J. C; Leung, K.; Beach, D. H.; Nabel, G. J. Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science, 1997, 275(5299), 523-527.
    • (1997) Science , vol.275 , Issue.5299 , pp. 523-527
    • Perkins, N.D.1    Felzien, L.K.2    Betts, J.C.3    Leung, K.4    Beach, D.H.5    Nabel, G.J.6
  • 154
    • 0034676269 scopus 로고    scopus 로고
    • The RelA NF-kappaB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells
    • Kim, D. W.; Gazourian, L.; Quadri, S. A.; Romieu-Mourez, R.; Sherr, D. H.; Sonenshein, G. E. The RelA NF-kappaB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells. Oncogene, 2000, 19(48), 5498-5506.
    • (2000) Oncogene , vol.19 , Issue.48 , pp. 5498-5506
    • Kim, D.W.1    Gazourian, L.2    Quadri, S.A.3    Romieu-Mourez, R.4    Sherr, D.H.5    Sonenshein, G.E.6
  • 155
    • 0034682527 scopus 로고    scopus 로고
    • Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells
    • Biswas, D. K.; Cruz, A. P.; Gansberger, E.; Pardee, A. B. Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. Proc. Natl. Acad. Sci. U S A, 2000, 97(15), 8542-8547.
    • (2000) Proc. Natl. Acad. Sci. U S A , vol.97 , Issue.15 , pp. 8542-8547
    • Biswas, D.K.1    Cruz, A.P.2    Gansberger, E.3    Pardee, A.B.4
  • 156
    • 69249126664 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis protein and its E3 ligase activity promote transforming growth factor-{beta}-mediated nuclear factor-{kappa} B activation during breast cancer progression
    • Neil, J. R.; Tian, M.; Schiemann, W. P. X-linked inhibitor of apoptosis protein and its E3 ligase activity promote transforming growth factor-{beta}-mediated nuclear factor-{kappa} B activation during breast cancer progression. J. Biol. Chem., 2009, 284(32), 21209-21217.
    • (2009) J. Biol. Chem. , vol.284 , Issue.32 , pp. 21209-21217
    • Neil, J.R.1    Tian, M.2    Schiemann, W.P.3
  • 157
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang, C. Y.; Mayo, M. W.; Korneluk, R. G.; Goeddel, D. V.; Baldwin, A. S., Jr. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science, 1998, 281(5383), 1680-1683.
    • (1998) Science , vol.281 , Issue.5383 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin, A.S.5
  • 159
    • 79960348853 scopus 로고    scopus 로고
    • Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-kappaB: Implication in breast cancer metastasis
    • Bist, P.; Leow, S. C; Phua, Q. H.; Shu, S.; Zhuang, Q.; Loh, W. T.; Nguyen, T. H.; Zhou, J. B.; Hooi, S. C; Lim, L. H. Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-kappaB: implication in breast cancer metastasis. Oncogene, 2011, 30(28), 3174-3185.
    • (2011) Oncogene , vol.30 , Issue.28 , pp. 3174-3185
    • Bist, P.1    Leow, S.C.2    Phua, Q.H.3    Shu, S.4    Zhuang, Q.5    Loh, W.T.6    Nguyen, T.H.7    Zhou, J.B.8    Hooi, S.C.9    Lim, L.H.10
  • 160
    • 0036479114 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and NF-kappaB regulate motility of invasive MDA-MB-231 human breast cancer cells by the secretion of urokinase-type plasminogen activator
    • Sliva, D.; Rizzo, M. T.; English, D. Phosphatidylinositol 3-kinase and NF-kappaB regulate motility of invasive MDA-MB-231 human breast cancer cells by the secretion of urokinase-type plasminogen activator. J. Biol. Chem., 2002, 277(5), 3150-3157.
    • (2002) J. Biol. Chem. , vol.277 , Issue.5 , pp. 3150-3157
    • Sliva, D.1    Rizzo, M.T.2    English, D.3
  • 161
    • 54349115394 scopus 로고    scopus 로고
    • Interleukin-8 expression is regulated by histone deacetylases through the nuclear factorkappaB pathway in breast cancer
    • Chavey, C; Muhlbauer, M.; Bossard, C; Freund, A.; Durand, S.; Jorgensen, C; Jobin, C; Lazennec, G. Interleukin-8 expression is regulated by histone deacetylases through the nuclear factorkappaB pathway in breast cancer. Mol. Pharmacol, 2008, 74(5), 1359-1366.
    • (2008) Mol. Pharmacol , vol.74 , Issue.5 , pp. 1359-1366
    • Chavey, C.1    Muhlbauer, M.2    Bossard, C.3    Freund, A.4    Durand, S.5    Jorgensen, C.6    Jobin, C.7    Lazennec, G.8
  • 162
    • 84867494076 scopus 로고    scopus 로고
    • Molecular pathways: VCAM-1 as a potential therapeutic target in metastasis
    • Chen, Q.; Massague, J. Molecular pathways: VCAM-1 as a potential therapeutic target in metastasis. Clin. Cancer Res., 2012, 18(20), 5520-5525.
    • (2012) Clin. Cancer Res. , vol.18 , Issue.20 , pp. 5520-5525
    • Chen, Q.1    Massague, J.2
  • 164
    • 80054074183 scopus 로고    scopus 로고
    • Thioredoxin stimulates MMP-9 expression, de-regulates the MMP-9/TIMP-1 equilibrium and promotes MMP-9 dependent invasion in human MDA-MB-231 breast cancer cells
    • Farina, A. R.; Cappabianca, L.; De Santis, G.; Di Ianni, N.; Ruggeri, P.; Ragone, M.; Merolle, S.; Tonissen, K. F.; Gulino, A.; Mackay, A. R. Thioredoxin stimulates MMP-9 expression, de-regulates the MMP-9/TIMP-1 equilibrium and promotes MMP-9 dependent invasion in human MDA-MB-231 breast cancer cells. FEBS Lett., 2011, 585(20), 3328-3336.
    • (2011) FEBS Lett. , vol.585 , Issue.20 , pp. 3328-3336
    • Farina, A.R.1    Cappabianca, L.2    De Santis, G.3    Di Ianni, N.4    Ruggeri, P.5    Ragone, M.6    Merolle, S.7    Tonissen, K.F.8    Gulino, A.9    Mackay, A.R.10
  • 165
    • 33846828787 scopus 로고    scopus 로고
    • NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: Potential involvement of ZEB-1 and ZEB-2
    • Chua, H. L.; Bhat-Nakshatri, P.; Clare, S. E.; Morimiya, A.; Badve, S.; Nakshatri, H. NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2. Oncogene, 2007, 26(5), 711-724.
    • (2007) Oncogene , vol.26 , Issue.5 , pp. 711-724
    • Chua, H.L.1    Bhat-Nakshatri, P.2    Clare, S.E.3    Morimiya, A.4    Badve, S.5    Nakshatri, H.6
  • 166
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
    • Wu, Y.; Deng, J.; Rychahou, P. G.; Qiu, S.; Evers, B. M.; Zhou, B. P. Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell, 2009, 15(5), 416-428.
    • (2009) Cancer Cell , vol.15 , Issue.5 , pp. 416-428
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3    Qiu, S.4    Evers, B.M.5    Zhou, B.P.6
  • 169
    • 0035990599 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB activity decreases the VEGF mRNA expression in MDA-MB-231 breast cancer cells
    • Shibata, A.; Nagaya, T.; Imai, T.; Funahashi, H.; Nakao, A.; Seo, H. Inhibition of NF-kappaB activity decreases the VEGF mRNA expression in MDA-MB-231 breast cancer cells. Breast Cancer Res. Treat., 2002, 73(3), 237-243.
    • (2002) Breast Cancer Res. Treat. , vol.73 , Issue.3 , pp. 237-243
    • Shibata, A.1    Nagaya, T.2    Imai, T.3    Funahashi, H.4    Nakao, A.5    Seo, H.6
  • 170
    • 84876070993 scopus 로고    scopus 로고
    • Role of NF-kappaB activation in matrix metalloproteinase 9, vascular endothelial growth factor and interleukin 8 expression and secretion in human breast cancer cells
    • Li, C; Guo, S.; Shi, T. Role of NF-kappaB activation in matrix metalloproteinase 9, vascular endothelial growth factor and interleukin 8 expression and secretion in human breast cancer cells. Cell Biochem Funct., 2013, 31(3), 263-268.
    • (2013) Cell Biochem Funct. , vol.31 , Issue.3 , pp. 263-268
    • Li, C.1    Guo, S.2    Shi, T.3
  • 171
    • 84872722039 scopus 로고    scopus 로고
    • Correlated expression of Fas, NF-kappaB, and VEGF-C in infiltrating ductal carcinoma of the breast
    • Dai, X. L.; Zhou, S. L.; Qiu, J.; Liu, Y. F.; Hua, H. Correlated expression of Fas, NF-kappaB, and VEGF-C in infiltrating ductal carcinoma of the breast. Eur. J. Gynaecol. Oncol, 2012, 33, 633-639.
    • (2012) Eur. J. Gynaecol. Oncol , vol.33 , pp. 633-639
    • Dai, X.L.1    Zhou, S.L.2    Qiu, J.3    Liu, Y.F.4    Hua, H.5
  • 172
    • 84883097117 scopus 로고    scopus 로고
    • NF-kappaB non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype
    • Yamamoto, M.; Taguchi, Y.; Ito-Kureha, T.; Semba, K.; Yamaguchi, N.; Inoue, J. NF-kappaB non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype. Nat. Commun., 2013, 4, 2299.
    • (2013) Nat. Commun. , vol.4 , pp. 2299
    • Yamamoto, M.1    Taguchi, Y.2    Ito-Kureha, T.3    Semba, K.4    Yamaguchi, N.5    Inoue, J.6
  • 173
    • 84867120285 scopus 로고    scopus 로고
    • Pathological and molecular diagnosis of triple-negative breast cancer: A clinical perspective
    • Penault-Llorca, F.; Viale, G. Pathological and molecular diagnosis of triple-negative breast cancer: a clinical perspective. Ann. Oncol, 2012, 23(Suppl 6), vi19-22.
    • (2012) Ann. Oncol , vol.23 , pp. vi19-vi22
    • Penault-Llorca, F.1    Viale, G.2
  • 174
    • 79952637468 scopus 로고    scopus 로고
    • Antitumor activity of Noscapine in combination with Doxorubicin in triple negative breast cancer
    • Chougule, M. B.; Patel, A. R.; Jackson, T.; Singh, M. Antitumor activity of Noscapine in combination with Doxorubicin in triple negative breast cancer. PloS on, e 2011, 6(3), e17733.
    • (2011) PloS On, e , vol.6 , Issue.3 , pp. e17733
    • Chougule, M.B.1    Patel, A.R.2    Jackson, T.3    Singh, M.4
  • 176
    • 68849108869 scopus 로고    scopus 로고
    • Inflammation and cancer: How friendly is the relationship for cancer patients
    • Aggarwal, B. B.; Gehlot, P., Inflammation and cancer: how friendly is the relationship for cancer patients. Curr. Opin. Pharmacol., 2009, 9(4), 351-369.
    • (2009) Curr. Opin. Pharmacol. , vol.9 , Issue.4 , pp. 351-369
    • Aggarwal, B.B.1    Gehlot, P.2
  • 177
    • 24644441893 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activator system and breast cancer (Review)
    • Han, B.; Nakamura, M.; Mori, I.; Nakamura, Y.; Kakudo, K., Urokinase-type plasminogen activator system and breast cancer (Review). Oncol. Rep., 2005, 14(1), 105-112.
    • (2005) Oncol. Rep. , vol.14 , Issue.1 , pp. 105-112
    • Han, B.1    Nakamura, M.2    Mori, I.3    Nakamura, Y.4    Kakudo, K.5
  • 178
    • 77952720802 scopus 로고    scopus 로고
    • Is there a role for mammary stem cells in inflammatory breast carcinoma?: A review of evidence from cell line, animal model, and human tissue sample experiments
    • Van Laere, S.; Limame, R.; Van Marck, E. A.; Vermeulen, P. B.; Dirix, L. Y., Is there a role for mammary stem cells in inflammatory breast carcinoma?: a review of evidence from cell line, animal model, and human tissue sample experiments. Cancer, 2010, 116(11 Suppl), 2794-2805.
    • (2010) Cancer , vol.116 , Issue.11 , pp. 2794-2805
    • Van Laere, S.1    Limame, R.2    Van Marck, E.A.3    Vermeulen, P.B.4    Dirix, L.Y.5
  • 179
    • 77649190700 scopus 로고    scopus 로고
    • Her2 activates NF-kappaB and induces invasion through the canonical pathway involving IKKalpha
    • Merkhofer, E. C.; Cogswell, P.; Baldwin, A. S., Her2 activates NF-kappaB and induces invasion through the canonical pathway involving IKKalpha. Oncogene, 2010, 29(8), 1238-1248.
    • (2010) Oncogene , vol.29 , Issue.8 , pp. 1238-1248
    • Merkhofer, E.C.1    Cogswell, P.2    Baldwin, A.S.3
  • 180
    • 2342641439 scopus 로고    scopus 로고
    • Upregulation of IKKalpha/IKKbeta by integrin-linked kinase is required for HER2/neu-induced NF-kappaB antiapoptotic pathway
    • Makino, K.; Day, C. P.; Wang, S. C.; Li, Y. M.; Hung, M. C., Upregulation of IKKalpha/IKKbeta by integrin-linked kinase is required for HER2/neu-induced NF-kappaB antiapoptotic pathway. Oncogene, 2004, 23(21), 3883-3887.
    • (2004) Oncogene , vol.23 , Issue.21 , pp. 3883-3887
    • Makino, K.1    Day, C.P.2    Wang, S.C.3    Li, Y.M.4    Hung, M.C.5
  • 183
    • 68149164966 scopus 로고    scopus 로고
    • The canonical NF-kappaB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population
    • Pratt, M. A.; Tibbo, E.; Robertson, S. J.; Jansson, D.; Hurst, K.; Perez-Iratxeta, C.; Lau, R.; Niu, M. Y., The canonical NF-kappaB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population. Oncogene, 2009, 28(30), 2710-2722.
    • (2009) Oncogene , vol.28 , Issue.30 , pp. 2710-2722
    • Pratt, M.A.1    Tibbo, E.2    Robertson, S.J.3    Jansson, D.4    Hurst, K.5    Perez-Iratxeta, C.6    Lau, R.7    Niu, M.Y.8
  • 184
    • 13944253943 scopus 로고    scopus 로고
    • CDK4 regulation by TNFR1 and JNK is required for NF-kappaB-mediated epidermal growth control
    • Zhang, J. Y.; Tao, S.; Kimmel, R.; Khavari, P. A., CDK4 regulation by TNFR1 and JNK is required for NF-kappaB-mediated epidermal growth control. J. Cell. Bio., 2005, 168(4), 561-566.
    • (2005) J. Cell. Bio. , vol.168 , Issue.4 , pp. 561-566
    • Zhang, J.Y.1    Tao, S.2    Kimmel, R.3    Khavari, P.A.4
  • 185
    • 40449120350 scopus 로고    scopus 로고
    • An oncogeneinduced DNA damage model for cancer development
    • Halazonetis, T. D.; Gorgoulis, V. G.; Bartek, J., An oncogeneinduced DNA damage model for cancer development. Science, 2008, 319(5868), 1352-1355.
    • (2008) Science , vol.319 , Issue.5868 , pp. 1352-1355
    • Halazonetis, T.D.1    Gorgoulis, V.G.2    Bartek, J.3
  • 186
    • 58149109907 scopus 로고    scopus 로고
    • Signalling loops and linear pathways: NF-kappaB activation in response to genotoxic stress
    • Brzoska, K.; Szumiel, I., Signalling loops and linear pathways: NF-kappaB activation in response to genotoxic stress. Mutagenesis, 2009, 24(1), 1-8.
    • (2009) Mutagenesis , vol.24 , Issue.1 , pp. 1-8
    • Brzoska, K.1    Szumiel, I.2
  • 187
    • 0242362757 scopus 로고    scopus 로고
    • Modulation of DNA repair processes by arsenic and selenium compounds
    • Hartwig, A.; Blessing, H.; Schwerdtle, T.; Walter, I., Modulation of DNA repair processes by arsenic and selenium compounds. Toxicology, 2003, 193(1-2), 161-169.
    • (2003) Toxicology , vol.193 , Issue.1-2 , pp. 161-169
    • Hartwig, A.1    Blessing, H.2    Schwerdtle, T.3    Walter, I.4
  • 188
    • 84855285493 scopus 로고    scopus 로고
    • NF-kappaB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes
    • Volcic, M.; Karl, S.; Baumann, B.; Salles, D.; Daniel, P.; Fulda, S.; Wiesmuller, L., NF-kappaB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes. Nucleic acids Res., 2012, 40(1), 181-195.
    • (2012) Nucleic Acids Res. , vol.40 , Issue.1 , pp. 181-195
    • Volcic, M.1    Karl, S.2    Baumann, B.3    Salles, D.4    Daniel, P.5    Fulda, S.6    Wiesmuller, L.7
  • 189
    • 84880869807 scopus 로고    scopus 로고
    • The complexity of NF-kappaB signaling in inflammation and cancer
    • Hoesel, B.; Schmid, J. A., The complexity of NF-kappaB signaling in inflammation and cancer. Mol. Cancer, 2013, 12, 86.
    • (2013) Mol. Cancer , vol.12 , pp. 86
    • Hoesel, B.1    Schmid, J.A.2
  • 190
    • 77549083560 scopus 로고    scopus 로고
    • Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer
    • Grivennikov, S. I.; Karin, M., Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer. Cytokine Growth Factor Rev., 2010, 21(1), 11-19.
    • (2010) Cytokine Growth Factor Rev. , vol.21 , Issue.1 , pp. 11-19
    • Grivennikov, S.I.1    Karin, M.2
  • 191
    • 34249868449 scopus 로고    scopus 로고
    • Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB
    • Yang, J.; Liao, X.; Agarwal, M. K.; Barnes, L.; Auron, P. E.; Stark, G. R., Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB. Genes Dev., 2007, 21(11), 1396-1408.
    • (2007) Genes Dev. , vol.21 , Issue.11 , pp. 1396-1408
    • Yang, J.1    Liao, X.2    Agarwal, M.K.3    Barnes, L.4    Auron, P.E.5    Stark, G.R.6
  • 194
    • 46949110625 scopus 로고    scopus 로고
    • A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women
    • Wang, Y.; Hu, Z.; Liang, J.; Wang, Z.; Tang, J.; Wang, S.; Wang, X.; Qin, J.; Shen, H., A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women. Carcinogenesis, 2008, 29(6), 1197-1201.
    • (2008) Carcinogenesis , vol.29 , Issue.6 , pp. 1197-1201
    • Wang, Y.1    Hu, Z.2    Liang, J.3    Wang, Z.4    Tang, J.5    Wang, S.6    Wang, X.7    Qin, J.8    Shen, H.9
  • 195
    • 84907029151 scopus 로고    scopus 로고
    • Noncanonical NF-kappaB activation mediates STAT3-stimulated IDO upregulation in myeloid-derived suppressor cells in breast cancer
    • Yu, J.; Wang, Y.; Yan, F.; Zhang, P.; Li, H.; Zhao, H.; Yan, C.; Ren, X., Noncanonical NF-kappaB Activation Mediates STAT3-Stimulated IDO Upregulation in Myeloid-Derived Suppressor Cells in Breast Cancer. J Immunol., 2014, 193(5), 2574-2586.
    • (2014) J Immunol. , vol.193 , Issue.5 , pp. 2574-2586
    • Yu, J.1    Wang, Y.2    Yan, F.3    Zhang, P.4    Li, H.5    Zhao, H.6    Yan, C.7    Ren, X.8
  • 196
    • 0034612636 scopus 로고    scopus 로고
    • Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
    • Hoeflich, K. P.; Luo, J.; Rubie, E. A.; Tsao, M. S.; Jin, O.; Woodgett, J. R., Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature, 2000, 406(6791), 86-90.
    • (2000) Nature , vol.406 , Issue.6791 , pp. 86-90
    • Hoeflich, K.P.1    Luo, J.2    Rubie, E.A.3    Tsao, M.S.4    Jin, O.5    Woodgett, J.R.6
  • 197
    • 57349143530 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy
    • Luo, J., Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy. Cancer Lett., 2009, 273(2), 194-200.
    • (2009) Cancer Lett. , vol.273 , Issue.2 , pp. 194-200
    • Luo, J.1
  • 198
    • 1542618320 scopus 로고    scopus 로고
    • Crossregulation of NF-kappaB by the APC/GSK-3beta/betacatenin pathway
    • Deng, J.; Xia, W.; Miller, S. A.; Wen, Y.; Wang, H. Y.; Hung, M. C., Crossregulation of NF-kappaB by the APC/GSK-3beta/betacatenin pathway. Mol. Carcinog., 2004, 39(3), 139-146.
    • (2004) Mol. Carcinog. , vol.39 , Issue.3 , pp. 139-146
    • Deng, J.1    Xia, W.2    Miller, S.A.3    Wen, Y.4    Wang, H.Y.5    Hung, M.C.6
  • 199
    • 33845806853 scopus 로고    scopus 로고
    • Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice
    • Wang, Y.; Lam, J. B.; Lam, K. S.; Liu, J.; Lam, M. C.; Hoo, R. L.; Wu, D.; Cooper, G. J.; Xu, A., Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice. Cancer Res., 2006, 66(23), 11462-11470.
    • (2006) Cancer Res. , vol.66 , Issue.23 , pp. 11462-11470
    • Wang, Y.1    Lam, J.B.2    Lam, K.S.3    Liu, J.4    Lam, M.C.5    Hoo, R.L.6    Wu, D.7    Cooper, G.J.8    Xu, A.9
  • 200
    • 79551478911 scopus 로고    scopus 로고
    • Beta-Catenin and NF-kappaB cooperate to regulate the uPA/uPAR system in cancer cells
    • Moreau, M.; Mourah, S.; Dosquet, C., beta-Catenin and NF-kappaB cooperate to regulate the uPA/uPAR system in cancer cells. Int. J. Cancer, 2011, 128(6), 1280-1292.
    • (2011) Int. J. Cancer , vol.128 , Issue.6 , pp. 1280-1292
    • Moreau, M.1    Mourah, S.2    Dosquet, C.3
  • 201
    • 0032954928 scopus 로고    scopus 로고
    • Transcriptional cross talk between NF-kappaB and p53
    • Webster, G. A.; Perkins, N. D., Transcriptional cross talk between NF-kappaB and p53. Mol. Cell Biol., 1999, 19(5), 3485-3495.
    • (1999) Mol. Cell Biol. , vol.19 , Issue.5 , pp. 3485-3495
    • Webster, G.A.1    Perkins, N.D.2
  • 202
    • 0034689773 scopus 로고    scopus 로고
    • Role of NF-kappaB in p53-mediated programmed cell death
    • Ryan, K. M.; Ernst, M. K.; Rice, N. R.; Vousden, K. H., Role of NF-kappaB in p53-mediated programmed cell death. Nature, 2000, 404(6780), 892-897.
    • (2000) Nature , vol.404 , Issue.6780 , pp. 892-897
    • Ryan, K.M.1    Ernst, M.K.2    Rice, N.R.3    Vousden, K.H.4
  • 204
    • 78650572907 scopus 로고    scopus 로고
    • NFkappaB/p53 crosstalk-a promising new therapeutic target
    • Schneider, G.; Kramer, O. H., NFkappaB/p53 crosstalk-a promising new therapeutic target. Biochim. Biophys. Acta, 2011, 1815(1), 90-103.
    • (2011) Biochim. Biophys. Acta , vol.1815 , Issue.1 , pp. 90-103
    • Schneider, G.1    Kramer, O.H.2
  • 206
    • 0141919562 scopus 로고    scopus 로고
    • PTEN reverses MDM2-mediated chemotherapy resistance by interacting with p53 in acute lymphoblastic leukemia cells
    • Zhou, M.; Gu, L.; Findley, H. W.; Jiang, R.; Woods, W. G., PTEN reverses MDM2-mediated chemotherapy resistance by interacting with p53 in acute lymphoblastic leukemia cells. Cancer Res., 2003, 63(19), 6357-6362.
    • (2003) Cancer Res. , vol.63 , Issue.19 , pp. 6357-6362
    • Zhou, M.1    Gu, L.2    Findley, H.W.3    Jiang, R.4    Woods, W.G.5
  • 207
    • 84871586311 scopus 로고    scopus 로고
    • P53-independent roles of MDM2 in NF-kappaB signaling: Implications for cancer therapy, wound healing, and autoimmune diseases
    • Thomasova, D.; Mulay, S. R.; Bruns, H.; Anders, H. J., p53-independent roles of MDM2 in NF-kappaB signaling: implications for cancer therapy, wound healing, and autoimmune diseases. Neoplasia, 2012, 14(12), 1097-1101.
    • (2012) Neoplasia , vol.14 , Issue.12 , pp. 1097-1101
    • Thomasova, D.1    Mulay, S.R.2    Bruns, H.3    Anders, H.J.4
  • 209
    • 0035868342 scopus 로고    scopus 로고
    • Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN
    • Pianetti, S.; Arsura, M.; Romieu-Mourez, R.; Coffey, R. J.; Sonenshein, G. E., Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN. Oncogene, 2001, 20(11), 1287-1299.
    • (2001) Oncogene , vol.20 , Issue.11 , pp. 1287-1299
    • Pianetti, S.1    Arsura, M.2    Romieu-Mourez, R.3    Coffey, R.J.4    Sonenshein, G.E.5
  • 210
    • 84885860445 scopus 로고    scopus 로고
    • P53 mutations in triple negative breast cancer upregulate endosomal recycling of epidermal growth factor receptor (EGFR) increasing its oncogenic potency
    • Shapira, I.; Lee, A.; Vora, R.; Budman, D. R., P53 mutations in triple negative breast cancer upregulate endosomal recycling of epidermal growth factor receptor (EGFR) increasing its oncogenic potency. Crit. Rev. Oncol. Hematol., 2013, 88(2), 284-292.
    • (2013) Crit. Rev. Oncol. Hematol. , vol.88 , Issue.2 , pp. 284-292
    • Shapira, I.1    Lee, A.2    Vora, R.3    Budman, D.R.4
  • 211
    • 84882586963 scopus 로고    scopus 로고
    • MiRNAs in cancer prevention and treatment and as molecular targets for natural product anticancer agents
    • Qian, B.; Nag, S. A.; Su, Y.; Voruganti, S.; Qin, J. J.; Zhang, R.; Cho, W. C., miRNAs in cancer prevention and treatment and as molecular targets for natural product anticancer agents. Curr. Cancer Drug Targets, 2013, 13(5), 519-541.
    • (2013) Curr. Cancer Drug Targets , vol.13 , Issue.5 , pp. 519-541
    • Qian, B.1    Nag, S.A.2    Su, Y.3    Voruganti, S.4    Qin, J.J.5    Zhang, R.6    Cho, W.C.7
  • 214
    • 52149102044 scopus 로고    scopus 로고
    • Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells
    • Bhaumik, D.; Scott, G. K.; Schokrpur, S.; Patil, C. K.; Campisi, J.; Benz, C. C., Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells. Oncogene, 2008, 27(42), 5643-5647.
    • (2008) Oncogene , vol.27 , Issue.42 , pp. 5643-5647
    • Bhaumik, D.1    Scott, G.K.2    Schokrpur, S.3    Patil, C.K.4    Campisi, J.5    Benz, C.C.6
  • 216
    • 84862689246 scopus 로고    scopus 로고
    • DNA damage induces NF-kappaB-dependent microRNA-21 up-regulation and promotes breast cancer cell invasion
    • Niu, J.; Shi, Y.; Tan, G.; Yang, C. H.; Fan, M.; Pfeffer, L. M.; Wu, Z. H., DNA damage induces NF-kappaB-dependent microRNA-21 up-regulation and promotes breast cancer cell invasion. J. Biol. Chem., 2012, 287(26), 21783-21795.
    • (2012) J. Biol. Chem. , vol.287 , Issue.26 , pp. 21783-21795
    • Niu, J.1    Shi, Y.2    Tan, G.3    Yang, C.H.4    Fan, M.5    Pfeffer, L.M.6    Wu, Z.H.7
  • 217
    • 84869801719 scopus 로고    scopus 로고
    • MiR-200c targets a NF-kappaB up-regulated TrkB/NTF3 autocrine signaling loop to enhance anoikis sensitivity in triple negative breast cancer
    • Howe, E. N.; Cochrane, D. R.; Cittelly, D. M.; Richer, J. K., miR-200c targets a NF-kappaB up-regulated TrkB/NTF3 autocrine signaling loop to enhance anoikis sensitivity in triple negative breast cancer. PloS one, 2012, 7(11), e49987.
    • (2012) PloS One , vol.7 , Issue.11 , pp. e49987
    • Howe, E.N.1    Cochrane, D.R.2    Cittelly, D.M.3    Richer, J.K.4
  • 220
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumors
    • The Cancer Genome Atlas Network, Comprehensive molecular portraits of human breast tumors. Nature, 2012, 490, 61-70.
    • (2012) Nature , vol.490 , pp. 61-70
    • The Cancer Genome Atlas Network1
  • 222
    • 42449097765 scopus 로고    scopus 로고
    • Reasons for breast cancer heterogeneity
    • Bertucci, F.; Birnbaum, D., Reasons for breast cancer heterogeneity. J. Biol., 2008, 7(2), 6.
    • (2008) J. Biol. , vol.7 , Issue.2 , pp. 6
    • Bertucci, F.1    Birnbaum, D.2
  • 223
    • 79952469959 scopus 로고    scopus 로고
    • Breast cancer heterogeneity: Mechanisms, proofs, and implications
    • Hsiao, Y. H.; Chou, M. C.; Fowler, C.; Mason, J. T.; Man, Y. G., Breast cancer heterogeneity: mechanisms, proofs, and implications. J. Cancer, 2010, 1, 6-13.
    • (2010) J. Cancer , vol.1 , pp. 6-13
    • Hsiao, Y.H.1    Chou, M.C.2    Fowler, C.3    Mason, J.T.4    Man, Y.G.5
  • 225
    • 84896502580 scopus 로고    scopus 로고
    • Invasive lobular carcinoma cell lines are characterized by unique estrogen-mediated gene expression patterns and altered tamoxifen response
    • Sikora, M. J.; Cooper, K. L.; Bahreini, A.; Luthra, S.; Wang, G.; Chandran, U. R.; Davidson, N. E.; Dabbs, D. J.; Welm, A. L.; Oesterreich, S., Invasive lobular carcinoma cell lines are characterized by unique estrogen-mediated gene expression patterns and altered tamoxifen response. Cancer Res., 2014. 74(5), 1463-1474.
    • (2014) Cancer Res. , vol.74 , Issue.5 , pp. 1463-1474
    • Sikora, M.J.1    Cooper, K.L.2    Bahreini, A.3    Luthra, S.4    Wang, G.5    Chandran, U.R.6    Davidson, N.E.7    Dabbs, D.J.8    Welm, A.L.9    Oesterreich, S.10
  • 226
    • 33645730357 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors
    • Creighton, C. J.; Hilger, A. M.; Murthy, S.; Rae, J. M.; Chinnaiyan, A. M.; El-Ashry, D., Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors. Cancer Res., 2006, 66(7), 3903-3911.
    • (2006) Cancer Res. , vol.66 , Issue.7 , pp. 3903-3911
    • Creighton, C.J.1    Hilger, A.M.2    Murthy, S.3    Rae, J.M.4    Chinnaiyan, A.M.5    El-Ashry, D.6
  • 228
    • 0030873289 scopus 로고    scopus 로고
    • Estrogen receptor impairs interleukin-6 expression by preventing protein binding on the NF-kappaB site
    • Galien, R.; Garcia, T., Estrogen receptor impairs interleukin-6 expression by preventing protein binding on the NF-kappaB site. Nucleic acids Res., 1997, 25(12), 2424-2429.
    • (1997) Nucleic Acids Res. , vol.25 , Issue.12 , pp. 2424-2429
    • Galien, R.1    Garcia, T.2
  • 230
    • 36849026193 scopus 로고    scopus 로고
    • PKCtheta promotes c-Rel-driven mammary tumorigenesis in mice and humans by repressing estrogen receptor alpha synthesis
    • Belguise, K.; Sonenshein, G. E., PKCtheta promotes c-Rel-driven mammary tumorigenesis in mice and humans by repressing estrogen receptor alpha synthesis. J. Clin. Invest., 2007, 117(12), 4009-4021.
    • (2007) J. Clin. Invest. , vol.117 , Issue.12 , pp. 4009-4021
    • Belguise, K.1    Sonenshein, G.E.2
  • 233
    • 34249701359 scopus 로고    scopus 로고
    • The effect of 17beta-estradiol on IL-6 secretion and NF-kappaB DNA-binding activity in human retinal pigment epithelial cells
    • Paimela, T.; Ryhanen, T.; Mannermaa, E.; Ojala, J.; Kalesnykas, G.; Salminen, A.; Kaarniranta, K., The effect of 17beta-estradiol on IL-6 secretion and NF-kappaB DNA-binding activity in human retinal pigment epithelial cells. Immunol. Lett., 2007, 110(2), 139-144.
    • (2007) Immunol. Lett. , vol.110 , Issue.2 , pp. 139-144
    • Paimela, T.1    Ryhanen, T.2    Mannermaa, E.3    Ojala, J.4    Kalesnykas, G.5    Salminen, A.6    Kaarniranta, K.7
  • 234
    • 34548632420 scopus 로고    scopus 로고
    • Despite inhibition of nuclear localization of NF-kappa B p65, c-Rel, and RelB, 17-beta estradiol up-regulates NF-kappa B signaling in mouse splenocytes: The potential role of Bcl-3
    • Dai, R.; Phillips, R. A.; Ahmed, S. A., Despite inhibition of nuclear localization of NF-kappa B p65, c-Rel, and RelB, 17-beta estradiol up-regulates NF-kappa B signaling in mouse splenocytes: the potential role of Bcl-3. J. Immunol., 2007, 179(3), 1776-1783.
    • (2007) J. Immunol. , vol.179 , Issue.3 , pp. 1776-1783
    • Dai, R.1    Phillips, R.A.2    Ahmed, S.A.3
  • 235
    • 16244373963 scopus 로고    scopus 로고
    • 17beta-estradiol inhibits inflammatory gene expression by controlling NF-kappaB intracellular localization
    • Ghisletti, S.; Meda, C.; Maggi, A.; Vegeto, E., 17beta-estradiol inhibits inflammatory gene expression by controlling NF-kappaB intracellular localization. Mol. Cell. Biol., 2005, 25(8), 2957-2968.
    • (2005) Mol. Cell. Biol. , vol.25 , Issue.8 , pp. 2957-2968
    • Ghisletti, S.1    Meda, C.2    Maggi, A.3    Vegeto, E.4
  • 236
    • 38749144353 scopus 로고    scopus 로고
    • CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor
    • Nettles, K. W.; Gil, G.; Nowak, J.; Metivier, R.; Sharma, V. B.; Greene, G. L., CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor. Mol Endocrinol., 2008, 22(2), 263-272.
    • (2008) Mol Endocrinol. , vol.22 , Issue.2 , pp. 263-272
    • Nettles, K.W.1    Gil, G.2    Nowak, J.3    Metivier, R.4    Sharma, V.B.5    Greene, G.L.6
  • 237
    • 32444436779 scopus 로고    scopus 로고
    • Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression
    • Cvoro, A.; Tzagarakis-Foster, C.; Tatomer, D.; Paruthiyil, S.; Fox, M. S.; Leitman, D. C., Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression. Mol. Cell, 2006, 21(4), 555-564.
    • (2006) Mol. Cell , vol.21 , Issue.4 , pp. 555-564
    • Cvoro, A.1    Tzagarakis-Foster, C.2    Tatomer, D.3    Paruthiyil, S.4    Fox, M.S.5    Leitman, D.C.6
  • 238
    • 71549124954 scopus 로고    scopus 로고
    • Positive cross-talk between estrogen receptor and NF-kappaB in breast cancer
    • Frasor, J.; Weaver, A.; Pradhan, M.; Dai, Y.; Miller, L. D.; Lin, C. Y.; Stanculescu, A., Positive cross-talk between estrogen receptor and NF-kappaB in breast cancer. Cancer Res., 2009, 69(23), 8918-8925.
    • (2009) Cancer Res. , vol.69 , Issue.23 , pp. 8918-8925
    • Frasor, J.1    Weaver, A.2    Pradhan, M.3    Dai, Y.4    Miller, L.D.5    Lin, C.Y.6    Stanculescu, A.7
  • 240
    • 33750467991 scopus 로고    scopus 로고
    • Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models
    • Gerondakis, S.; Grumont, R.; Gugasyan, R.; Wong, L.; Isomura, I.; Ho, W.; Banerjee, A., Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models. Oncogene, 2006, 25(51), 6781-6799.
    • (2006) Oncogene , vol.25 , Issue.51 , pp. 6781-6799
    • Gerondakis, S.1    Grumont, R.2    Gugasyan, R.3    Wong, L.4    Isomura, I.5    Ho, W.6    Banerjee, A.7
  • 241
    • 0033596123 scopus 로고    scopus 로고
    • Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: Transgenics and knockouts
    • Gerondakis, S.; Grossmann, M.; Nakamura, Y.; Pohl, T.; Grumont, R., Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts. Oncogene, 1999, 18(49), 6888-6895.
    • (1999) Oncogene , vol.18 , Issue.49 , pp. 6888-6895
    • Gerondakis, S.1    Grossmann, M.2    Nakamura, Y.3    Pohl, T.4    Grumont, R.5
  • 242
    • 4544228457 scopus 로고    scopus 로고
    • Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology
    • Beinke, S.; Ley, S. C., Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology. Biochem. J., 2004, 382(Pt 2), 393-409.
    • (2004) Biochem. J. , vol.382 , pp. 393-409
    • Beinke, S.1    Ley, S.C.2
  • 243
    • 33750454819 scopus 로고    scopus 로고
    • Mutations in the NF-kappaB signaling pathway: Implications for human disease
    • Courtois, G.; Gilmore, T. D., Mutations in the NF-kappaB signaling pathway: implications for human disease. Oncogene, 2006, 25(51), 6831-6843.
    • (2006) Oncogene , vol.25 , Issue.51 , pp. 6831-6843
    • Courtois, G.1    Gilmore, T.D.2
  • 244
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
    • Beg, A. A.; Sha, W. C.; Bronson, R. T.; Ghosh, S.; Baltimore, D., Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature, 1995, 376(6536), 167-170.
    • (1995) Nature , vol.376 , Issue.6536 , pp. 167-170
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Ghosh, S.4    Baltimore, D.5
  • 245
    • 0035861314 scopus 로고    scopus 로고
    • IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development
    • Cao, Y.; Bonizzi, G.; Seagroves, T. N.; Greten, F. R.; Johnson, R.; Schmidt, E. V.; Karin, M., IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development. Cell, 2001, 107(6), 763-775.
    • (2001) Cell , vol.107 , Issue.6 , pp. 763-775
    • Cao, Y.1    Bonizzi, G.2    Seagroves, T.N.3    Greten, F.R.4    Johnson, R.5    Schmidt, E.V.6    Karin, M.7
  • 246
    • 77649341172 scopus 로고    scopus 로고
    • Targeting transcription factor NF-kappaB to overcome chemoresistance and radioresistance in cancer therapy
    • Li, F.; Sethi, G., Targeting transcription factor NF-kappaB to overcome chemoresistance and radioresistance in cancer therapy. Biochim. Biophys. Acta, 2010, 1805(2), 167-180.
    • (2010) Biochim. Biophys. Acta , vol.1805 , Issue.2 , pp. 167-180
    • Li, F.1    Sethi, G.2
  • 247
    • 69249137029 scopus 로고    scopus 로고
    • Biological determinants of endocrine resistance in breast cancer
    • Musgrove, E. A.; Sutherland, R. L., Biological determinants of endocrine resistance in breast cancer. Nat. Rev. Cancer, 2009, 9(9), 631-643.
    • (2009) Nat. Rev. Cancer , vol.9 , Issue.9 , pp. 631-643
    • Musgrove, E.A.1    Sutherland, R.L.2
  • 248
    • 77957764181 scopus 로고    scopus 로고
    • Proinflammatory cytokines enhance estrogen-dependent expression of the multidrug transporter gene ABCG2 through estrogen receptor and NF{kappa}B cooperativity at adjacent response elements
    • Pradhan, M.; Bembinster, L. A.; Baumgarten, S. C.; Frasor, J., Proinflammatory cytokines enhance estrogen-dependent expression of the multidrug transporter gene ABCG2 through estrogen receptor and NF{kappa}B cooperativity at adjacent response elements. J. Biol. Chem., 2010, 285(41), 31100-31106.
    • (2010) J. Biol. Chem. , vol.285 , Issue.41 , pp. 31100-31106
    • Pradhan, M.1    Bembinster, L.A.2    Baumgarten, S.C.3    Frasor, J.4
  • 249
    • 77955274748 scopus 로고    scopus 로고
    • Transcriptional suppression of breast cancer resistance protein (BCRP) by wild-type p53 through the NF-kappaB pathway in MCF-7 cells
    • Wang, X.; Wu, X.; Wang, C.; Zhang, W.; Ouyang, Y.; Yu, Y.; He, Z., Transcriptional suppression of breast cancer resistance protein (BCRP) by wild-type p53 through the NF-kappaB pathway in MCF-7 cells. FEBS letters, 2010, 584(15), 3392-3397.
    • (2010) FEBS Letters , vol.584 , Issue.15 , pp. 3392-3397
    • Wang, X.1    Wu, X.2    Wang, C.3    Zhang, W.4    Ouyang, Y.5    Yu, Y.6    He, Z.7
  • 250
    • 84870810356 scopus 로고    scopus 로고
    • Clusterin confers resistance to TNF-alpha-induced apoptosis in breast cancer cells through NF-kappaB activation and Bcl-2 overexpression
    • Wang, Y.; Wang, X.; Zhao, H.; Liang, B.; Du, Q., Clusterin confers resistance to TNF-alpha-induced apoptosis in breast cancer cells through NF-kappaB activation and Bcl-2 overexpression. J. Chemother., 2012, 24(6), 348-357.
    • (2012) J. Chemother. , vol.24 , Issue.6 , pp. 348-357
    • Wang, Y.1    Wang, X.2    Zhao, H.3    Liang, B.4    Du, Q.5
  • 251
    • 84880872866 scopus 로고    scopus 로고
    • Survivin up-regulates the expression of breast cancer resistance protein (BCRP) through attenuating the suppression of p53 on NF-kappaB expression in MCF-7/5-FU cells
    • Wang, Q. P.; Wang, Y.; Wang, X. D.; Mo, X. M.; Gu, J.; Lu, Z. Y.; Pan, Z. L.; Zhu, Y. X., Survivin up-regulates the expression of breast cancer resistance protein (BCRP) through attenuating the suppression of p53 on NF-kappaB expression in MCF-7/5-FU cells. Int. J. Biochem. Cell Biol., 2013, 45(9), 2036-2044.
    • (2013) Int. J. Biochem. Cell Biol. , vol.45 , Issue.9 , pp. 2036-2044
    • Wang, Q.P.1    Wang, Y.2    Wang, X.D.3    Mo, X.M.4    Gu, J.5    Lu, Z.Y.6    Pan, Z.L.7    Zhu, Y.X.8
  • 253
    • 20144365514 scopus 로고    scopus 로고
    • Nuclear factor-kappaB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-kappaB-dependent transcription in cancer cells
    • Ho, W. C.; Dickson, K. M.; Barker, P. A., Nuclear factor-kappaB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-kappaB-dependent transcription in cancer cells. Cancer Res., 2005, 65(10), 4273-4281.
    • (2005) Cancer Res. , vol.65 , Issue.10 , pp. 4273-4281
    • Ho, W.C.1    Dickson, K.M.2    Barker, P.A.3
  • 256
    • 15944379896 scopus 로고    scopus 로고
    • Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation
    • Park, K. J.; Krishnan, V.; O'Malley, B. W.; Yamamoto, Y.; Gaynor, R. B., Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation. Mol. Cell, 2005, 18(1), 71-82.
    • (2005) Mol. Cell , vol.18 , Issue.1 , pp. 71-82
    • Park, K.J.1    Krishnan, V.2    O'Malley, B.W.3    Yamamoto, Y.4    Gaynor, R.B.5
  • 258
    • 0036006698 scopus 로고    scopus 로고
    • IkappaB kinase activation is involved in regulation of paclitaxel-induced apoptosis in human tumor cell lines
    • Huang, Y.; Fan, W., IkappaB kinase activation is involved in regulation of paclitaxel-induced apoptosis in human tumor cell lines. Mol. Pharmacol., 2002, 61(1), 105-113.
    • (2002) Mol. Pharmacol. , vol.61 , Issue.1 , pp. 105-113
    • Huang, Y.1    Fan, W.2
  • 259
    • 84879098177 scopus 로고    scopus 로고
    • NF-kappaB regulates radioresistance mediated by beta1-integrin in three-dimensional culture of breast cancer cells
    • Ahmed, K. M.; Zhang, H.; Park, C. C., NF-kappaB regulates radioresistance mediated by beta1-integrin in three-dimensional culture of breast cancer cells. Cancer Res., 2013, 73(12), 3737-3748.
    • (2013) Cancer Res. , vol.73 , Issue.12 , pp. 3737-3748
    • Ahmed, K.M.1    Zhang, H.2    Park, C.C.3
  • 260
    • 0025879694 scopus 로고
    • Ionizing radiation induces expression and binding activity of the nuclear factor kappa B
    • Brach, M. A.; Hass, R.; Sherman, M. L.; Gunji, H.; Weichselbaum, R.; Kufe, D., Ionizing radiation induces expression and binding activity of the nuclear factor kappa B. J. Clin. Invest., 1991, 88(2), 691-695.
    • (1991) J. Clin. Invest. , vol.88 , Issue.2 , pp. 691-695
    • Brach, M.A.1    Hass, R.2    Sherman, M.L.3    Gunji, H.4    Weichselbaum, R.5    Kufe, D.6
  • 261
    • 0032573165 scopus 로고    scopus 로고
    • Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms.
    • Li, N.; Karin, M., Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms., Proc. Natl. Acad. Sci. USA., 1998, 95(22), 13012-13017.
    • (1998) Proc. Natl. Acad. Sci. USA. , vol.95 , Issue.22 , pp. 13012-13017
    • Li, N.1    Karin, M.2
  • 262
    • 33846327627 scopus 로고    scopus 로고
    • Nuclear factor-kappaB p65 inhibits mitogen-activated protein kinase signaling pathway in radioresistant breast cancer cells
    • Ahmed, K. M.; Dong, S.; Fan, M.; Li, J. J., Nuclear factor-kappaB p65 inhibits mitogen-activated protein kinase signaling pathway in radioresistant breast cancer cells. Mol. Cancer Res., 2006, 4(12), 945-955.
    • (2006) Mol. Cancer Res. , vol.4 , Issue.12 , pp. 945-955
    • Ahmed, K.M.1    Dong, S.2    Fan, M.3    Li, J.J.4
  • 264
    • 68149145788 scopus 로고    scopus 로고
    • Molecular targets of nutraceuticals derived from dietary spices: Potential role in suppression of inflammation and tumorigenesis
    • Aggarwal, B. B.; Van Kuiken, M. E.; Iyer, L. H.; Harikumar, K. B.; Sung, B., Molecular targets of nutraceuticals derived from dietary spices: potential role in suppression of inflammation and tumorigenesis. Exp. Biol. Med. (Maywood), 2009, 234(8), 825-849.
    • (2009) Exp. Biol. Med. (Maywood) , vol.234 , Issue.8 , pp. 825-849
    • Aggarwal, B.B.1    Van Kuiken, M.E.2    Iyer, L.H.3    Harikumar, K.B.4    Sung, B.5
  • 265
    • 27144468987 scopus 로고    scopus 로고
    • Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice
    • Aggarwal, B. B.; Shishodia, S.; Takada, Y.; Banerjee, S.; Newman, R. A.; Bueso-Ramos, C. E.; Price, J. E., Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice. Clin. Cancer Res., 2005, 11(20), 7490-7498.
    • (2005) Clin. Cancer Res. , vol.11 , Issue.20 , pp. 7490-7498
    • Aggarwal, B.B.1    Shishodia, S.2    Takada, Y.3    Banerjee, S.4    Newman, R.A.5    Bueso-Ramos, C.E.6    Price, J.E.7
  • 267
    • 84865039191 scopus 로고    scopus 로고
    • Ginsenosides as anticancer agents: In vitro and in vivo activities, structure-activity relationships, and molecular mechanisms of action
    • Nag, S. A.; Qin, J. J.; Wang, W.; Wang, M. H.; Wang, H.; Zhang, R., Ginsenosides as Anticancer Agents: In vitro and in vivo Activities, Structure-Activity Relationships, and Molecular Mechanisms of Action. Front. Pharmacol., 2012, 3, 25.
    • (2012) Front. Pharmacol. , vol.3 , pp. 25
    • Nag, S.A.1    Qin, J.J.2    Wang, W.3    Wang, M.H.4    Wang, H.5    Zhang, R.6
  • 268
    • 84907293011 scopus 로고    scopus 로고
    • Suppression of PMA-induced tumor cell invasion and migration by ginsenoside Rg1 via the inhibition of NF-kappaB-dependent MMP-9 expression
    • Li, L.; Wang, Y.; Qi, B.; Yuan, D.; Dong, S.; Guo, D.; Zhang, C.; Yu, M., Suppression of PMA-induced tumor cell invasion and migration by ginsenoside Rg1 via the inhibition of NF-kappaB-dependent MMP-9 expression. Oncol. Rep., 2014, 32(5), 1779-1786.
    • (2014) Oncol. Rep. , vol.32 , Issue.5 , pp. 1779-1786
    • Li, L.1    Wang, Y.2    Qi, B.3    Yuan, D.4    Dong, S.5    Guo, D.6    Zhang, C.7    Yu, M.8
  • 269
    • 84925437706 scopus 로고    scopus 로고
    • Ginsenoside Rg3 inhibits constitutive activation of NF-kB signaling in human breast cancer (MDA-MB-231) cells: ERK and Akt as potential upstream targets
    • Kim, B. M.; Kim, D. H.; Park, J. H.; Surh, Y. J.; Na, H. K., Ginsenoside Rg3 Inhibits Constitutive Activation of NF-kB Signaling in Human Breast Cancer (MDA-MB-231) Cells: ERK and Akt as Potential Upstream Targets. J. Cancer. Prev., 2014, 19, 23-30.
    • (2014) J. Cancer. Prev. , vol.19 , pp. 23-30
    • Kim, B.M.1    Kim, D.H.2    Park, J.H.3    Surh, Y.J.4    Na, H.K.5
  • 270
    • 70450228666 scopus 로고    scopus 로고
    • American Ginseng inhibits induced COX-2 and NFKB activation in breast cancer cells
    • Peralta, E. A.; Murphy, L. L.; Minnis, J.; Louis, S.; Dunnington, G. L., American Ginseng inhibits induced COX-2 and NFKB activation in breast cancer cells. J. Surg. Res., 2009, 157(2), 261-267.
    • (2009) J. Surg. Res. , vol.157 , Issue.2 , pp. 261-267
    • Peralta, E.A.1    Murphy, L.L.2    Minnis, J.3    Louis, S.4    Dunnington, G.L.5
  • 272
    • 33645305415 scopus 로고    scopus 로고
    • Association of ginseng use with survival and quality of life among breast cancer patients
    • Cui, Y.; Shu, X. O.; Gao, Y. T.; Cai, H.; Tao, M. H.; Zheng, W., Association of ginseng use with survival and quality of life among breast cancer patients. Am. J. Epedemiol, 2006, 163(7), 645-653.
    • (2006) Am. J. Epedemiol , vol.163 , Issue.7 , pp. 645-653
    • Cui, Y.1    Shu, X.O.2    Gao, Y.T.3    Cai, H.4    Tao, M.H.5    Zheng, W.6
  • 275
    • 53349118240 scopus 로고    scopus 로고
    • SN52, a novel nuclear factor-kappaB inhibitor, blocks nuclear import of RelB: P52 dimer and sensitizes prostate cancer cells to ionizing radiation
    • Xu, Y.; Fang, F.; St Clair, D. K.; Sompol, P.; Josson, S.; St Clair, W. H., SN52, a novel nuclear factor-kappaB inhibitor, blocks nuclear import of RelB: p52 dimer and sensitizes prostate cancer cells to ionizing radiation. Mol. Cancer Ther., 2008, 7(8), 2367-2376.
    • (2008) Mol. Cancer Ther. , vol.7 , Issue.8 , pp. 2367-2376
    • Xu, Y.1    Fang, F.2    St Clair, D.K.3    Sompol, P.4    Josson, S.5    St Clair, W.H.6
  • 277
    • 84875988418 scopus 로고    scopus 로고
    • Mechanistic evaluation of the signaling events regulating curcumin-mediated chemosensitization of breast cancer cells to 5-fluorouracil
    • Vinod, B. S.; Antony, J.; Nair, H. H.; Puliyappadamba, V. T.; Saikia, M.; Narayanan, S. S.; Bevin, A.; Anto, R. J., Mechanistic evaluation of the signaling events regulating curcumin-mediated chemosensitization of breast cancer cells to 5-fluorouracil. Cell Death Dis., 2013, 4, e505.
    • (2013) Cell Death Dis. , vol.4 , pp. e505
    • Vinod, B.S.1    Antony, J.2    Nair, H.H.3    Puliyappadamba, V.T.4    Saikia, M.5    Narayanan, S.S.6    Bevin, A.7    Anto, R.J.8
  • 278
    • 56549112749 scopus 로고    scopus 로고
    • Cell penetrating peptide inhibitors of nuclear factor-kappa B
    • Orange, J. S.; May, M. J., Cell penetrating peptide inhibitors of nuclear factor-kappa B. Cell Mol. Life Sci., 2008, 65(22), 3564-3591.
    • (2008) Cell Mol. Life Sci. , vol.65 , Issue.22 , pp. 3564-3591
    • Orange, J.S.1    May, M.J.2
  • 280
    • 84925389505 scopus 로고    scopus 로고
    • The radiosensitizing and cytotoxic effects of PBS-1086, a Rel inhibitor of NF-KB, in breast cancer cells
    • Hunter, J. E.; Willmore, E.; Irving, J. A.; Sliskovic, D.; Monie, D.; Bobb, K.; Zhang, J.; Durkacz, B. W. The radiosensitizing and cytotoxic effects of PBS-1086, a Rel inhibitor of NF-KB, in breast cancer cells. Cancer Res., 2010, 70(8 Supplement), 3561.
    • (2010) Cancer Res. , vol.70 , Issue.8 , pp. 3561
    • Hunter, J.E.1    Willmore, E.2    Irving, J.A.3    Sliskovic, D.4    Monie, D.5    Bobb, K.6    Zhang, J.7    Durkacz, B.W.8
  • 282
    • 51649112926 scopus 로고    scopus 로고
    • NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells
    • Zhou, J.; Zhang, H.; Gu, P.; Bai, J.; Margolick, J. B.; Zhang, Y., NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells. Breast Cancer Res. Treat., 2008, 111(3), 419-427.
    • (2008) Breast Cancer Res. Treat. , vol.111 , Issue.3 , pp. 419-427
    • Zhou, J.1    Zhang, H.2    Gu, P.3    Bai, J.4    Margolick, J.B.5    Zhang, Y.6
  • 284
    • 12944273470 scopus 로고    scopus 로고
    • Targeting of nuclear factor kappaB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: Antitumor and antiangiogenic potential in vivo
    • Matsumoto, G.; Namekawa, J.; Muta, M.; Nakamura, T.; Bando, H.; Tohyama, K.; Toi, M.; Umezawa, K., Targeting of nuclear factor kappaB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo. Clin. Cancer Res., 2005, 11(3), 1287-1293.
    • (2005) Clin. Cancer Res. , vol.11 , Issue.3 , pp. 1287-1293
    • Matsumoto, G.1    Namekawa, J.2    Muta, M.3    Nakamura, T.4    Bando, H.5    Tohyama, K.6    Toi, M.7    Umezawa, K.8
  • 285
    • 33646851955 scopus 로고    scopus 로고
    • Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation
    • Takada, Y.; Gillenwater, A.; Ichikawa, H.; Aggarwal, B. B., Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation. J. Biol. Chem., 2006, 281(9), 5612-5622.
    • (2006) J. Biol. Chem. , vol.281 , Issue.9 , pp. 5612-5622
    • Takada, Y.1    Gillenwater, A.2    Ichikawa, H.3    Aggarwal, B.B.4
  • 286
    • 52949120373 scopus 로고    scopus 로고
    • Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells
    • Domingo-Domenech, J.; Pippa, R.; Tapia, M.; Gascon, P.; Bachs, O.; Bosch, M., Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells. Breast Cancer Res. Treat., 2008, 112(1), 53-62.
    • (2008) Breast Cancer Res. Treat. , vol.112 , Issue.1 , pp. 53-62
    • Domingo-Domenech, J.1    Pippa, R.2    Tapia, M.3    Gascon, P.4    Bachs, O.5    Bosch, M.6
  • 289
    • 84859822652 scopus 로고    scopus 로고
    • Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages
    • Fernandes, C. A.; Fievez, L.; Neyrinck, A. M.; Delzenne, N. M.; Bureau, F.; Vanbever, R., Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages. Biochem. Biophys. Res. Comm., 2012, 420(4), 857-861.
    • (2012) Biochem. Biophys. Res. Comm. , vol.420 , Issue.4 , pp. 857-861
    • Fernandes, C.A.1    Fievez, L.2    Neyrinck, A.M.3    Delzenne, N.M.4    Bureau, F.5    Vanbever, R.6
  • 291
    • 79951702955 scopus 로고    scopus 로고
    • Bortezomib as the first proteasome inhibitor anticancer drug: Current status and future perspectives
    • Chen, D.; Frezza, M.; Schmitt, S.; Kanwar, J.; Dou, Q. P., Bortezomib as the first proteasome inhibitor anticancer drug: current status and future perspectives. Curr. Cancer Drug Targets, 2011, 11(3), 239-253.
    • (2011) Curr. Cancer Drug Targets , vol.11 , Issue.3 , pp. 239-253
    • Chen, D.1    Frezza, M.2    Schmitt, S.3    Kanwar, J.4    Dou, Q.P.5
  • 293
    • 84906816792 scopus 로고    scopus 로고
    • Multiple myeloma maintenance therapy: A review of the pharmacologic treatment
    • Shank, B. R.; Brown, V. T.; Schwartz, R. N., Multiple myeloma maintenance therapy: A review of the pharmacologic treatment. J. Oncol. Pharm. Pract., 2014.
    • (2014) J. Oncol. Pharm. Pract.
    • Shank, B.R.1    Brown, V.T.2    Schwartz, R.N.3
  • 294
    • 84855430944 scopus 로고    scopus 로고
    • Molecular pathways: Targeting proteasomal protein degradation in cancer
    • Molineaux, S. M., Molecular pathways: targeting proteasomal protein degradation in cancer. Clin. Cancer Res., 2012, 18(1), 15-20.
    • (2012) Clin. Cancer Res. , vol.18 , Issue.1 , pp. 15-20
    • Molineaux, S.M.1
  • 295
    • 84876730349 scopus 로고    scopus 로고
    • Targeting of NF-kappaB signaling pathway, other signaling pathways and epigenetics in therapy of multiple myeloma
    • Fuchs, O., Targeting of NF-kappaB signaling pathway, other signaling pathways and epigenetics in therapy of multiple myeloma. Cardiovasc. Hematol Disord. Drug Targets, 2013, 13(1), 16-34.
    • (2013) Cardiovasc. Hematol Disord. Drug Targets , vol.13 , Issue.1 , pp. 16-34
    • Fuchs, O.1
  • 297
    • 84883137533 scopus 로고    scopus 로고
    • IMD-0354 targets breast cancer stem cells: A novel approach for an adjuvant to chemotherapy to prevent multidrug resistance in a murine model
    • Gomez-Cabrero, A.; Wrasidlo, W.; Reisfeld, R. A., IMD-0354 targets breast cancer stem cells: a novel approach for an adjuvant to chemotherapy to prevent multidrug resistance in a murine model. PloS one, 2013, 8(8), e73607.
    • (2013) PloS One , vol.8 , Issue.8 , pp. e73607
    • Gomez-Cabrero, A.1    Wrasidlo, W.2    Reisfeld, R.A.3
  • 299
    • 84876787970 scopus 로고    scopus 로고
    • The nuclear factor-kappaB pathway down-regulates expression of the NKG2D ligand H60a in vitro: Implications for use of nuclear factor-kappaB inhibitors in cancer therapy
    • Peinado, C; Kang, X.; Hardamon, C; Arora, S.; Mah, S.; Zhang, H.; Ngolab, J.; Bui, J. D., The nuclear factor-kappaB pathway down-regulates expression of the NKG2D ligand H60a in vitro: implications for use of nuclear factor-kappaB inhibitors in cancer therapy. Immunology, 2013, 139(2), 265-274.
    • (2013) Immunology , vol.139 , Issue.2 , pp. 265-274
    • Peinado, C.1    Kang, X.2    Hardamon, C.3    Arora, S.4    Mah, S.5    Zhang, H.6    Ngolab, J.7    Bui, J.D.8
  • 301
    • 34447333110 scopus 로고    scopus 로고
    • Nuclear factor-kappaB activation: A molecular therapeutic target for estrogen receptor-negative and epidermal growth factor receptor family receptor-positive human breast cancer
    • Singh, S.; Shi, Q.; Bailey, S. T.; Palczewski, M. J.; Pardee, A. B.; Iglehart, J. D.; Biswas, D. K., Nuclear factor-kappaB activation: a molecular therapeutic target for estrogen receptor-negative and epidermal growth factor receptor family receptor-positive human breast cancer. Mol. Cancer Ther., 2007, 6(7), 1973-1982.
    • (2007) Mol. Cancer Ther. , vol.6 , Issue.7 , pp. 1973-1982
    • Singh, S.1    Shi, Q.2    Bailey, S.T.3    Palczewski, M.J.4    Pardee, A.B.5    Iglehart, J.D.6    Biswas, D.K.7
  • 302
    • 84884125055 scopus 로고    scopus 로고
    • Denosumab for the treatment of bone metastases in advanced breast cancer
    • Casas, A.; Llombart, A.; Martin, M., Denosumab for the treatment of bone metastases in advanced breast cancer. Breast, 2013, 22(5), 585-592.
    • (2013) Breast , vol.22 , Issue.5 , pp. 585-592
    • Casas, A.1    Llombart, A.2    Martin, M.3
  • 303
    • 84879931794 scopus 로고    scopus 로고
    • The effect of curcumin on breast cancer cells
    • Liu, D.; Chen, Z., The effect of curcumin on breast cancer cells. J. Breast Cancer, 2013, 16(2), 133-137.
    • (2013) J. Breast Cancer , vol.16 , Issue.2 , pp. 133-137
    • Liu, D.1    Chen, Z.2
  • 305
    • 50349098189 scopus 로고    scopus 로고
    • Targeting nuclear factorkappa B activation pathway by thymoquinone: Role in suppression of antiapoptotic gene products and enhancement of apoptosis
    • Sethi, G.; Ahn, K. S.; Aggarwal, B. B., Targeting nuclear factorkappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis. Mol. Cancer Res., 2008, 6(6), 1059-1070.
    • (2008) Mol. Cancer Res. , vol.6 , Issue.6 , pp. 1059-1070
    • Sethi, G.1    Ahn, K.S.2    Aggarwal, B.B.3
  • 306
    • 84875313028 scopus 로고    scopus 로고
    • Tocotrienols promote apoptosis in human breast cancer cells by inducing poly (ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity
    • Loganathan, R.; Selvaduray, K. R.; Nesaretnam, K.; Radhakrishnan, A. K., Tocotrienols promote apoptosis in human breast cancer cells by inducing poly (ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity. Cell Prolif., 2013, 46(2), 203-213.
    • (2013) Cell Prolif. , vol.46 , Issue.2 , pp. 203-213
    • Loganathan, R.1    Selvaduray, K.R.2    Nesaretnam, K.3    Radhakrishnan, A.K.4
  • 307
    • 84857060149 scopus 로고    scopus 로고
    • Hydrogen sulfide-releasing aspirin suppresses NF-kappaB signaling in estrogen receptor negative breast cancer cells in vitro and in vivo
    • Chattopadhyay, M.; Kodela, R.; Nath, N.; Barsegian, A.; Boring, D.; Kashfi, K., Hydrogen sulfide-releasing aspirin suppresses NF-kappaB signaling in estrogen receptor negative breast cancer cells in vitro and in vivo. Biochem. Pharmacol. 2012, 83(6), 723-732.
    • (2012) Biochem. Pharmacol. , vol.83 , Issue.6 , pp. 723-732
    • Chattopadhyay, M.1    Kodela, R.2    Nath, N.3    Barsegian, A.4    Boring, D.5    Kashfi, K.6
  • 308
    • 2442651752 scopus 로고    scopus 로고
    • Aspirin and breast cancer prevention - The estrogen connection
    • Du Bois, R. N., Aspirin and breast cancer prevention - The estrogen connection. J. Am. Med. Assoc., 2004, 291(20), 2488-2489.
    • (2004) J. Am. Med. Assoc. , vol.291 , Issue.20 , pp. 2488-2489
    • Du Bois, R.N.1
  • 310
    • 34247892406 scopus 로고    scopus 로고
    • Dexamethasone as a chemosensitizer for breast cancer chemotherapy: Potentiation of the antitumor activity of adriamycin, modulation of cytokine expression, and pharmacokinetics
    • Wang, H.; Wang, Y.; Rayburn, E. R.; Hill, D. L.; Rinehart, J. J.; Zhang, R., Dexamethasone as a chemosensitizer for breast cancer chemotherapy: potentiation of the antitumor activity of adriamycin, modulation of cytokine expression, and pharmacokinetics. Int. J. Oncol., 2007, 30(4), 947-953.
    • (2007) Int. J. Oncol. , vol.30 , Issue.4 , pp. 947-953
    • Wang, H.1    Wang, Y.2    Rayburn, E.R.3    Hill, D.L.4    Rinehart, J.J.5    Zhang, R.6
  • 312
    • 0034908034 scopus 로고    scopus 로고
    • Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: An in vitro study
    • Denoyelle, C.; Vasse, M.; Korner, M.; Mishal, Z.; Ganne, F.; Vannier, J. P.; Soria, J.; Soria, C., Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: an in vitro study. Carcinogenesis, 2001, 22(8), 1139-1148.
    • (2001) Carcinogenesis , vol.22 , Issue.8 , pp. 1139-1148
    • Denoyelle, C.1    Vasse, M.2    Korner, M.3    Mishal, Z.4    Ganne, F.5    Vannier, J.P.6    Soria, J.7    Soria, C.8
  • 315
    • 84977107124 scopus 로고    scopus 로고
    • Highlights and summary of the 28th annual meeting of the Society for Immunotherapy of Cancer
    • Ascierto, Paolo A.; Munn, D. H.; Palucka, A. K.; Sondel, P. M., Highlights and summary of the 28th annual meeting of the Society for Immunotherapy of Cancer. J. Immunother. Cancer, 2014, 2, 15.
    • (2014) J. Immunother. Cancer , vol.2 , pp. 15
    • Ascierto, P.A.1    Munn, D.H.2    Palucka, A.K.3    Sondel, P.M.4
  • 316
    • 84883715434 scopus 로고    scopus 로고
    • Selective cytotoxicity, inhibition of cell cycle progression, and induction of apoptosis in human breast cancer cells by sesquiterpenoids from Inula lineariifolia Turcz
    • Qin, J. J.; Jin, H. Z.; Huang, Y.; Zhang, S. D.; Shan, L.; Voruganti, S.; Nag, S.; Wang, W.; Zhang, W. D.; Zhang, R., Selective cytotoxicity, inhibition of cell cycle progression, and induction of apoptosis in human breast cancer cells by sesquiterpenoids from Inula lineariifolia Turcz. Eur. J. Med. Chem., 2013, 68, 473-481.
    • (2013) Eur. J. Med. Chem. , vol.68 , pp. 473-481
    • Qin, J.J.1    Jin, H.Z.2    Huang, Y.3    Zhang, S.D.4    Shan, L.5    Voruganti, S.6    Nag, S.7    Wang, W.8    Zhang, W.D.9    Zhang, R.10
  • 319
    • 84873732176 scopus 로고    scopus 로고
    • NF-kappaB signaling pathway and free radical impact
    • Siomek, A., NF-kappaB signaling pathway and free radical impact. Acta Biochim. Pol., 2012, 59(3), 323-331.
    • (2012) Acta Biochim. Pol. , vol.59 , Issue.3 , pp. 323-331
    • Siomek, A.1
  • 320
    • 0033596126 scopus 로고    scopus 로고
    • Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway
    • Epinat, J. C.; Gilmore, T. D., Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway. Oncogene, 1999, 18(49), 6896-6909.
    • (1999) Oncogene , vol.18 , Issue.49 , pp. 6896-6909
    • Epinat, J.C.1    Gilmore, T.D.2
  • 321
    • 71549169241 scopus 로고    scopus 로고
    • Theaflavins retard human breast cancer cell migration by inhibiting NF-kappaB via p53-ROS cross-talk
    • Adhikary, A.; Mohanty, S.; Lahiry, L.; Hossain, D. M.; Chakraborty, S.; Das, T., Theaflavins retard human breast cancer cell migration by inhibiting NF-kappaB via p53-ROS cross-talk. FEBS Lett., 2010, 584(1), 7-14.
    • (2010) FEBS Lett. , vol.584 , Issue.1 , pp. 7-14
    • Adhikary, A.1    Mohanty, S.2    Lahiry, L.3    Hossain, D.M.4    Chakraborty, S.5    Das, T.6
  • 322
    • 0024413057 scopus 로고
    • ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin
    • Eytan, E.; Ganoth, D.; Armon, T.; Hershko, A., ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin. Proc. Natl. Acad. Sci. USA., 1989, 86(20), 7751-7755.
    • (1989) Proc. Natl. Acad. Sci. USA. , vol.86 , Issue.20 , pp. 7751-7755
    • Eytan, E.1    Ganoth, D.2    Armon, T.3    Hershko, A.4
  • 323
    • 84859827831 scopus 로고    scopus 로고
    • The proteasome: Molecular machinery and pathophysiological roles
    • Tanaka, K.; Mizushima, T.; Saeki, Y., The proteasome: molecular machinery and pathophysiological roles. Biol. Chem., 2012, 393(4), 217-234.
    • (2012) Biol. Chem. , vol.393 , Issue.4 , pp. 217-234
    • Tanaka, K.1    Mizushima, T.2    Saeki, Y.3
  • 324
    • 84856373151 scopus 로고    scopus 로고
    • Proteasome inhibitors: An expanding army attacking a unique target
    • Kisselev, A. F.; Van Der Linden, W. A.; Overkleeft, H. S., Proteasome inhibitors: an expanding army attacking a unique target. Chem. Biol., 2012, 19(1), 99-115.
    • (2012) Chem. Biol. , vol.19 , Issue.1 , pp. 99-115
    • Kisselev, A.F.1    Van Der Linden, W.A.2    Overkleeft, H.S.3
  • 329
    • 84873699578 scopus 로고    scopus 로고
    • Overexpression of p65 attenuates celecoxib-induced cell death in MDA-MB-231 human breast cancer cell line
    • Wang, L.; Kang, F.; Li, J.; Zhang, J.; Shan, B., Overexpression of p65 attenuates celecoxib-induced cell death in MDA-MB-231 human breast cancer cell line. Cancer Cell Int., 2013, 13(1), 14.
    • (2013) Cancer Cell Int. , vol.13 , Issue.1 , pp. 14
    • Wang, L.1    Kang, F.2    Li, J.3    Zhang, J.4    Shan, B.5
  • 330
    • 0033578879 scopus 로고    scopus 로고
    • Sulindac inhibits activation of the NF-kappaB pathway
    • Yamamoto, Y.; Yin, M. J.; Lin, K. M.; Gaynor, R. B., Sulindac inhibits activation of the NF-kappaB pathway. J. Biol. Chem., 1999, 274(38), 27307-27314.
    • (1999) J. Biol. Chem. , vol.274 , Issue.38 , pp. 27307-27314
    • Yamamoto, Y.1    Yin, M.J.2    Lin, K.M.3    Gaynor, R.B.4
  • 331
    • 0028831128 scopus 로고
    • Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors
    • Scheinman, R. I.; Gualberto, A.; Jewell, C. M.; Cidlowski, J. A.; Baldwin, A. S., Jr., Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors. Mol. Cell Biol., 1995, 15(2), 943-953.
    • (1995) Mol. Cell Biol. , vol.15 , Issue.2 , pp. 943-953
    • Scheinman, R.I.1    Gualberto, A.2    Jewell, C.M.3    Cidlowski, J.A.4    Baldwin, A.S.5
  • 332
    • 0034464826 scopus 로고    scopus 로고
    • CBP (CREB binding protein) integrates NF-kappaB (nuclear factor-kappaB) and glucocorticoid receptor physical interactions and antagonism
    • McKay, L. I.; Cidlowski, J. A., CBP (CREB binding protein) integrates NF-kappaB (nuclear factor-kappaB) and glucocorticoid receptor physical interactions and antagonism. Mol. Endocrinol., 2000, 14(8), 1222-1234.
    • (2000) Mol. Endocrinol. , vol.14 , Issue.8 , pp. 1222-1234
    • McKay, L.I.1    Cidlowski, J.A.2
  • 333
    • 84856259390 scopus 로고    scopus 로고
    • Inhibitory kappa B Kinases as targets for pharmacological regulation
    • Gamble, C.; McIntosh, K.; Scott, R.; Ho, K. H.; Plevin, R.; Paul, A., Inhibitory kappa B Kinases as targets for pharmacological regulation. Br. J. Pharmacol., 2012, 165(4), 802-819.
    • (2012) Br. J. Pharmacol. , vol.165 , Issue.4 , pp. 802-819
    • Gamble, C.1    McIntosh, K.2    Scott, R.3    Ho, K.H.4    Plevin, R.5    Paul, A.6
  • 334
    • 3042716638 scopus 로고    scopus 로고
    • NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis
    • Biswas, D. K.; Shi, Q.; Baily, S.; Strickland, I.; Ghosh, S.; Pardee, A. B.; Iglehart, J. D., NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis. Proc. Natl. Acad. Sci. USA., 2004, 101(27), 10137-10142.
    • (2004) Proc. Natl. Acad. Sci. USA. , vol.101 , Issue.27 , pp. 10137-10142
    • Biswas, D.K.1    Shi, Q.2    Baily, S.3    Strickland, I.4    Ghosh, S.5    Pardee, A.B.6    Iglehart, J.D.7
  • 337
    • 21244472975 scopus 로고    scopus 로고
    • IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
    • Maeda, S.; Kamata, H.; Luo, J. L.; Leffert, H.; Karin, M., IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell, 2005, 121(7), 977-990.
    • (2005) Cell , vol.121 , Issue.7 , pp. 977-990
    • Maeda, S.1    Kamata, H.2    Luo, J.L.3    Leffert, H.4    Karin, M.5
  • 338
    • 37049027338 scopus 로고    scopus 로고
    • Nuclear factor-kappaB, an unappreciated tumor suppressor
    • Chen, F.; Castranova, V., Nuclear factor-kappaB, an unappreciated tumor suppressor. Cancer Res., 2007, 67(23), 11093-11098.
    • (2007) Cancer Res. , vol.67 , Issue.23 , pp. 11093-11098
    • Chen, F.1    Castranova, V.2
  • 339
    • 81255192180 scopus 로고    scopus 로고
    • The two faces of NF-kappaB signaling in cancer development and therapy
    • Klein, U.; Ghosh, S., The Two Faces of NF-kappaB Signaling in Cancer Development and Therapy. Cancer Cell, 2011, 20(5), 556-558.
    • (2011) Cancer Cell , vol.20 , Issue.5 , pp. 556-558
    • Klein, U.1    Ghosh, S.2
  • 340
    • 84884127454 scopus 로고    scopus 로고
    • Friend or foe: Emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence
    • Mowla, S. N.; Perkins, N. D.; Jat, P. S., Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence. Onco. Targets Ther., 2013, 6, 1221-1229.
    • (2013) Onco. Targets Ther. , vol.6 , pp. 1221-1229
    • Mowla, S.N.1    Perkins, N.D.2    Jat, P.S.3
  • 341
    • 0442323562 scopus 로고    scopus 로고
    • NF-kappaB: Tumor promoter or suppressor?
    • Perkins, N. D., NF-kappaB: tumor promoter or suppressor? Trends Cell Biol., 2004, 14(2), 64-69.
    • (2004) Trends Cell Biol. , vol.14 , Issue.2 , pp. 64-69
    • Perkins, N.D.1
  • 342
    • 84864087098 scopus 로고    scopus 로고
    • NF-kappaB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppression
    • Liu, F.; Bardhan, K.; Yang, D.; Thangaraju, M.; Ganapathy, V.; Waller, J. L.; Liles, G. B.; Lee, J. R.; Liu, K., NF-kappaB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppression. J. Biol. Chem., 2012, 287(30), 25530-25540.
    • (2012) J. Biol. Chem. , vol.287 , Issue.30 , pp. 25530-25540
    • Liu, F.1    Bardhan, K.2    Yang, D.3    Thangaraju, M.4    Ganapathy, V.5    Waller, J.L.6    Liles, G.B.7    Lee, J.R.8    Liu, K.9
  • 346
    • 84875812144 scopus 로고    scopus 로고
    • Genetically engineered mouse models of PI3K signaling in breast cancer
    • Klarenbeek, S.; Van Miltenburg, M. H.; Jonkers, J., Genetically engineered mouse models of PI3K signaling in breast cancer. Mol. Oncol., 2013, 7(2), 146-164.
    • (2013) Mol. Oncol. , vol.7 , Issue.2 , pp. 146-164
    • Klarenbeek, S.1    Van Miltenburg, M.H.2    Jonkers, J.3
  • 347
    • 84863561591 scopus 로고    scopus 로고
    • Oncogenic PI3K mutations lead to NF-kappaB-dependent cytokine expression following growth factor deprivation
    • Hutti, J. E.; Pfefferle, A. D.; Russell, S. C.; Sircar, M.; Perou, C. M.; Baldwin, A. S., Oncogenic PI3K mutations lead to NF-kappaB-dependent cytokine expression following growth factor deprivation. Cancer Res., 2012, 72(13), 3260-3269.
    • (2012) Cancer Res. , vol.72 , Issue.13 , pp. 3260-3269
    • Hutti, J.E.1    Pfefferle, A.D.2    Russell, S.C.3    Sircar, M.4    Perou, C.M.5    Baldwin, A.S.6
  • 348
    • 34248385769 scopus 로고    scopus 로고
    • Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine
    • Marczylo, T. H.; Verschoyle, R. D.; Cooke, D. N.; Morazzoni, P.; Steward, W. P.; Gescher, A. J., Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine. Cancer Chem. Pharmacol., 2007, 60(2), 171-177.
    • (2007) Cancer Chem. Pharmacol. , vol.60 , Issue.2 , pp. 171-177
    • Marczylo, T.H.1    Verschoyle, R.D.2    Cooke, D.N.3    Morazzoni, P.4    Steward, W.P.5    Gescher, A.J.6
  • 349
    • 84856725493 scopus 로고    scopus 로고
    • Doseescalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers
    • Kanai, M.; Imaizumi, A.; Otsuka, Y.; Sasaki, H.; Hashiguchi, M.; Tsujiko, K.; Matsumoto, S.; Ishiguro, H.; Chiba, T., Doseescalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers. Cancer Chem. Pharmacol., 2012, 69(1), 65-70.
    • (2012) Cancer Chem. Pharmacol. , vol.69 , Issue.1 , pp. 65-70
    • Kanai, M.1    Imaizumi, A.2    Otsuka, Y.3    Sasaki, H.4    Hashiguchi, M.5    Tsujiko, K.6    Matsumoto, S.7    Ishiguro, H.8    Chiba, T.9


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