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Volumn 228, Issue 9, 2003, Pages 995-1003

Apoptosis, chemoresistance, and breast cancer: Insights from the MCF-7 cell model system

Author keywords

Apoptosis; Ceramide; Chemoresistance; MCF 7 cells; Tumor necrosis factor

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE 9; CYTOCHROME C; DNA; ESTROGEN RECEPTOR; FAS ANTIBODY; FAS ANTIGEN; FAS LIGAND; FLUOROURACIL; FULVESTRANT; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN KINASE C INHIBITOR; PROTEIN P53; PROTEIN P55; RAF PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNINDEXED DRUG;

EID: 0141864377     PISSN: 15353702     EISSN: None     Source Type: Journal    
DOI: 10.1177/153537020322800903     Document Type: Short Survey
Times cited : (207)

References (81)
  • 3
    • 0027173231 scopus 로고
    • Estimates of the worldwide incidence of eighteen major cancers in 1985
    • Parkin DM, Pisani P, Ferlay J. Estimates of the worldwide incidence of eighteen major cancers in 1985. Int J Cancer 54:594-606, 1993.
    • (1993) Int J Cancer , vol.54 , pp. 594-606
    • Parkin, D.M.1    Pisani, P.2    Ferlay, J.3
  • 4
    • 0003789178 scopus 로고    scopus 로고
    • American Cancer Society, Atlanta, GA
    • American Cancer Society. Cancer Facts and Figures. American Cancer Society, Atlanta, GA, 1996.
    • (1996) Cancer Facts and Figures
  • 5
    • 0029809910 scopus 로고    scopus 로고
    • Apoptosis and angiogenesis: Two promising tumor markers in breast cancer
    • Wu J. Apoptosis and angiogenesis: two promising tumor markers in breast cancer (review). Anticancer Res 16:2233-2240, 1996.
    • (1996) Anticancer Res , vol.16 , pp. 2233-2240
    • Wu, J.1
  • 6
  • 7
    • 0034654326 scopus 로고    scopus 로고
    • Activation of apoptosis pathways by anticancer treatment
    • Debatin A-K. Activation of apoptosis pathways by anticancer treatment. Toxicol Lett 112-113:41-48, 2000.
    • (2000) Toxicol Lett , vol.112-113 , pp. 41-48
    • Debatin, A.-K.1
  • 9
    • 0035971181 scopus 로고    scopus 로고
    • Phosphatidylinositol/3-kinase/Akt-mediated activation of estrogen receptor α: A new model for anti-estrogen receptor resistance
    • Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H. Phosphatidylinositol/3-kinase/Akt-mediated activation of estrogen receptor α: A new model for anti-estrogen receptor resistance. J Biol Chem 276:9817-9824, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 9817-9824
    • Campbell, R.A.1    Bhat-Nakshatri, P.2    Patel, N.M.3    Constantinidou, D.4    Ali, S.5    Nakshatri, H.6
  • 10
    • 0030802967 scopus 로고    scopus 로고
    • MCF-7: The first hormone-responsive breast cancer cell line
    • Levenson AS, Jordan CV. MCF-7: The first hormone-responsive breast cancer cell line. Cancer Res 57:3071-3078, 1997.
    • (1997) Cancer Res , vol.57 , pp. 3071-3078
    • Levenson, A.S.1    Jordan, C.V.2
  • 11
    • 0015762456 scopus 로고
    • A human cell line from a pleural effusion derived from a breast carcinoma
    • Soule HD, Vazquez J, Long A, Albert S, Brennan M. A human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer Inst 51:1409-1416, 1973.
    • (1973) J Natl Cancer Inst , vol.51 , pp. 1409-1416
    • Soule, H.D.1    Vazquez, J.2    Long, A.3    Albert, S.4    Brennan, M.5
  • 12
    • 0032782306 scopus 로고    scopus 로고
    • Strain-specific differences in formation of apoptotic DNA ladders in MCF-7 breast cancer cells
    • Gooch JL, Yee D. Strain-specific differences in formation of apoptotic DNA ladders in MCF-7 breast cancer cells. Cancer Lett 144:31-37, 1999.
    • (1999) Cancer Lett , vol.144 , pp. 31-37
    • Gooch, J.L.1    Yee, D.2
  • 14
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JFR, Wyllie AH, Currie AR. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257, 1972.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 15
    • 0000381690 scopus 로고    scopus 로고
    • Signal transduction during apoptosis: Implications for cancer therapy
    • Story M, Kodym R. Signal transduction during apoptosis: Implications for cancer therapy. Frontiers Biosci 3:d365-d375, 1998.
    • (1998) Frontiers Biosci , vol.3
    • Story, M.1    Kodym, R.2
  • 16
    • 0033231485 scopus 로고    scopus 로고
    • Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-α-induced apoptosis
    • Liu Y-Y, Han T-Y, Giuliao AE, Ichikawa S, Hirabayashi Y, Cabot MC. Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-α-induced apoptosis. Exp Cell Res 252:464-470, 1999.
    • (1999) Exp Cell Res , vol.252 , pp. 464-470
    • Liu, Y.-Y.1    Han, T.-Y.2    Giuliao, A.E.3    Ichikawa, S.4    Hirabayashi, Y.5    Cabot, M.C.6
  • 17
    • 0032863163 scopus 로고    scopus 로고
    • All along the watchtower: On the regulation of apoptosis regulators
    • Fadeel B, Zhivotovsky B, Orrenius S. All along the watchtower: On the regulation of apoptosis regulators. FASEB J 13:1647-1657, 1999.
    • (1999) FASEB J , vol.13 , pp. 1647-1657
    • Fadeel, B.1    Zhivotovsky, B.2    Orrenius, S.3
  • 18
    • 0033082995 scopus 로고    scopus 로고
    • IAP family proteins: Suppressors of apoptosis
    • Deveraux QL, Reed JC. IAP family proteins: Suppressors of apoptosis. Genes Dev 13:239-252, 1999.
    • (1999) Genes Dev , vol.13 , pp. 239-252
    • Deveraux, Q.L.1    Reed, J.C.2
  • 19
    • 0034794571 scopus 로고    scopus 로고
    • The surviving saga goes in vivo
    • Reed JC. The surviving saga goes in vivo. J Clin Invest 108:965-969, 2001.
    • (2001) J Clin Invest , vol.108 , pp. 965-969
    • Reed, J.C.1
  • 20
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
    • Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB. J Clin Invest 197:241-246, 2001.
    • (2001) J Clin Invest , vol.197 , pp. 241-246
    • Baldwin, A.S.1
  • 21
    • 0034881019 scopus 로고    scopus 로고
    • Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals
    • Ballif BA, Blenis J. Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals. Cell Growth Differ 12:397-408, 2001.
    • (2001) Cell Growth Differ , vol.12 , pp. 397-408
    • Ballif, B.A.1    Blenis, J.2
  • 22
    • 0034630167 scopus 로고    scopus 로고
    • Induction of apoptosis by cancer chemotherapy
    • Kaufamnn SH, Earnshaw WC. Induction of apoptosis by cancer chemotherapy. Exp Cell Res 256:42-49, 2000.
    • (2000) Exp Cell Res , vol.256 , pp. 42-49
    • Kaufamnn, S.H.1    Earnshaw, W.C.2
  • 23
    • 0032582524 scopus 로고    scopus 로고
    • Analysis of human breast adenocarcinoma MCF-7 resistance to tumor necrosis factor-induced cell death
    • Ameyar M, Atfi A, Zhenzi C, Stancou R, Shatrov V, Bettaieb A, Chouaib S. Analysis of human breast adenocarcinoma MCF-7 resistance to tumor necrosis factor-induced cell death. J Biol Chem 273:29002-29008, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 29002-29008
    • Ameyar, M.1    Atfi, A.2    Zhenzi, C.3    Stancou, R.4    Shatrov, V.5    Bettaieb, A.6    Chouaib, S.7
  • 24
    • 0031966318 scopus 로고    scopus 로고
    • Chemosensitivity of solid tumor cells in vitro is related to activation of the CD95 system
    • Fulda S, Los M, Friesen C, Debatin K-M. Chemosensitivity of solid tumor cells in vitro is related to activation of the CD95 system. Int J Cancer 76:105-114, 1998.
    • (1998) Int J Cancer , vol.76 , pp. 105-114
    • Fulda, S.1    Los, M.2    Friesen, C.3    Debatin, K.-M.4
  • 25
    • 0035736491 scopus 로고    scopus 로고
    • The role of fas and fasL as mediators of anticancer chemotherapy
    • Poulaki V, Mitsiades CS, Mitsiades N. The role of fas and fasL as mediators of anticancer chemotherapy. Drug Resist Updat 4:233-242, 2001.
    • (2001) Drug Resist Updat , vol.4 , pp. 233-242
    • Poulaki, V.1    Mitsiades, C.S.2    Mitsiades, N.3
  • 26
    • 0034667357 scopus 로고    scopus 로고
    • Interferon-y treatment elevates caspase-8 expression and sensitizes human breast tumor cells to a death receptor-induced mitochondria-operated apoptotic program
    • Ruiz-Ruiz C, Munoz-Pinedo C, Lopez-Rivas A. Interferon-y treatment elevates caspase-8 expression and sensitizes human breast tumor cells to a death receptor-induced mitochondria-operated apoptotic program. Cancer Res 60:5673-5680, 2000.
    • (2000) Cancer Res , vol.60 , pp. 5673-5680
    • Ruiz-Ruiz, C.1    Munoz-Pinedo, C.2    Lopez-Rivas, A.3
  • 28
    • 0028175470 scopus 로고
    • Resistance to TNF-α and adriamycin in the human breast cancer MCF-7 cell line: Relationship to MDR1, MnSOD, and TNF gene expression
    • Zyad A, Benard J, Tursz T, Clarke R, Chouaib S. Resistance to TNF-α and adriamycin in the human breast cancer MCF-7 cell line: Relationship to MDR1, MnSOD, and TNF gene expression. Cancer Res 54:825-831, 1994
    • (1994) Cancer Res , vol.54 , pp. 825-831
    • Zyad, A.1    Benard, J.2    Tursz, T.3    Clarke, R.4    Chouaib, S.5
  • 29
    • 0036570007 scopus 로고    scopus 로고
    • The role of thymidylate synthase induction in modulating p53-regulated gene expression in response to 5-fluorouracil and antifolates
    • Longley DB, Boyer J, Allen WL, Latif T. Ferguson PR, Maxwell PJ, McDermott U, Lynch M, Harkin DP, et al. The role of thymidylate synthase induction in modulating p53-regulated gene expression in response to 5-fluorouracil and antifolates. Cancer Res 62:2644-2649, 2002.
    • (2002) Cancer Res , vol.62 , pp. 2644-2649
    • Longley, D.B.1    Boyer, J.2    Allen, W.L.3    Latif, T.4    Ferguson, P.R.5    Maxwell, P.J.6    McDermott, U.7    Lynch, M.8    Harkin, D.P.9
  • 30
    • 0033636080 scopus 로고    scopus 로고
    • A new method of antitumor therapy with a high dose of TNF perfusion for nonresectable liver tumors
    • Nakamoto T, Ingawa H, Takagi K, Soma G. A new method of antitumor therapy with a high dose of TNF perfusion for nonresectable liver tumors. Anticancer Res 20:4087-4096, 2000.
    • (2000) Anticancer Res , vol.20 , pp. 4087-4096
    • Nakamoto, T.1    Ingawa, H.2    Takagi, K.3    Soma, G.4
  • 33
    • 1842367285 scopus 로고    scopus 로고
    • Apoptosis. Placing death under control
    • Wallach D. Apoptosis. Placing death under control. Nature 388:123,125-126, 1997.
    • (1997) Nature 388 , vol.123 , pp. 125-126
    • Wallach, D.1
  • 34
    • 0030841911 scopus 로고    scopus 로고
    • I-FLICE a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis
    • Hu S, Vncenz C, Ni J, Gentz R, Dixit VM. I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J Biol Chem 272:17255-17257, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 17255-17257
    • Hu, S.1    Vncenz, C.2    Ni, J.3    Gentz, R.4    Dixit, V.M.5
  • 36
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
    • Earnshow WC, Martins LM, Kaufmann SH. Mammalian caspases: Structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem 68:383-424, 1999.
    • (1999) Annu Rev Biochem , vol.68 , pp. 383-424
    • Earnshow, W.C.1    Martins, L.M.2    Kaufmann, S.H.3
  • 37
    • 0032918249 scopus 로고    scopus 로고
    • p53 stress signaling cascades are altered in MCF-7 cells resistant to tumor necrosis factor-mediated apoptosis
    • Doman RK, Perez M, Danto NJ. JNK and p53 stress signaling cascades are altered in MCF-7 cells resistant to tumor necrosis factor-mediated apoptosis. J Interferon Cytokine Res 19:261-269, 1999.
    • (1999) J Interferon Cytokine Res , vol.19 , pp. 261-269
    • Doman, R.K.1    Perez, M.2    Danto, N.J.J.N.K.3
  • 38
    • 0033598352 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of wild-type p53 gene sensitizes TNF resistant MCF7 derivatives to the cytotoxic effect of this cytokine: Relationship with c-myc and Rb
    • Ameyar M, Shatrov V, Bouquet C, Capoulade C, Cai Z, Stancou R, Badie C, Haddada H, Chouaib S. Adenovirus-mediated transfer of wild-type p53 gene sensitizes TNF resistant MCF7 derivatives to the cytotoxic effect of this cytokine: Relationship with c-myc and Rb. Oncogene 18:5464-5472, 1999.
    • (1999) Oncogene , vol.18 , pp. 5464-5472
    • Ameyar, M.1    Shatrov, V.2    Bouquet, C.3    Capoulade, C.4    Cai, Z.5    Stancou, R.6    Badie, C.7    Haddada, H.8    Chouaib, S.9
  • 39
    • 0034016975 scopus 로고    scopus 로고
    • Cell death induced by TNF or serum starvation is independent of ErbB receptor signaling in MCF-7 breast carcinoma cells
    • Egeblad M, Jaatela M. Cell death induced by TNF or serum starvation is independent of ErbB receptor signaling in MCF-7 breast carcinoma cells. Int J Cancer 86:617-625.
    • Int J Cancer , vol.86 , pp. 617-625
    • Egeblad, M.1    Jaatela, M.2
  • 40
    • 0033179760 scopus 로고    scopus 로고
    • Bcl-2 family members and the mitochondria in apoptosis
    • Gross A, McDonnell JM, Korsmeyer SJ. Bcl-2 family members and the mitochondria in apoptosis. Genes Dev 13:1899-1911, 1999.
    • (1999) Genes Dev , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 41
    • 0035525733 scopus 로고    scopus 로고
    • Cellular stress response and apoptosis in cancer therapy
    • Herr I, Debatin K-M. Cellular stress response and apoptosis in cancer therapy. Blood 98:2603-2614, 2001.
    • (2001) Blood , vol.98 , pp. 2603-2614
    • Herr, I.1    Debatin, K.-M.2
  • 42
    • 0032925195 scopus 로고    scopus 로고
    • Antioxidant defenses in TNF-related MCF-7 cells: Selective increase in MnSOD
    • Siemankowski LM, Morreale, Briehl MM. Antioxidant defenses in TNF-related MCF-7 cells: Selective increase in MnSOD. Free Radic Biol Med 26:919-924, 1999.
    • (1999) Free Radic Biol Med , vol.26 , pp. 919-924
    • Siemankowski, L.M.1    Morreale2    Briehl, M.M.3
  • 43
  • 44
    • 0035807288 scopus 로고    scopus 로고
    • Apoptosis in the absence of caspase 3
    • Liang Y, Yan C, Schor NF. Apoptosis in the absence of caspase 3. Oncogene 20:6570-6578, 2001.
    • (2001) Oncogene , vol.20 , pp. 6570-6578
    • Liang, Y.1    Yan, C.2    Schor, N.F.3
  • 45
    • 0040298568 scopus 로고    scopus 로고
    • Caspase- 3 is required for DNA fragmentation and morphological changes associated with apoptosis
    • Janicke RU, Sprengart ML, Wati MR, Porter AG. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J Biol Chem 273:9357-9360, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 9357-9360
    • Janicke, R.U.1    Sprengart, M.L.2    Wati, M.R.3    Porter, A.G.4
  • 46
    • 0032724653 scopus 로고    scopus 로고
    • Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation
    • WolfBB, Schuler M, Echeverri F, Green DR. Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation. J Biol Chem 274:30651-30656, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 30651-30656
    • Wolf, B.B.1    Schuler, M.2    Echeverri, F.3    Green, D.R.4
  • 47
    • 0035132464 scopus 로고    scopus 로고
    • Reconstitution of caspase-3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis
    • Yang XH, Sladek TL, Liu X, Butler BR, Froelich CJ, Thor AD. Reconstitution of caspase-3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis. Cancer Res 61:348-354, 2001.
    • (2001) Cancer Res , vol.61 , pp. 348-354
    • Yang, X.H.1    Sladek, T.L.2    Liu, X.3    Butler, B.R.4    Froelich, C.J.5    Thor, A.D.6
  • 48
    • 0033231485 scopus 로고    scopus 로고
    • Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-α-induced apoptosis
    • Liu Y-Y, Han T-Y, Giuliano AE, Ichikawa S, Hirabayashi Y, Cabot MC. Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-α-induced apoptosis. Exp Cell Res 252:464-470, 1999.
    • (1999) Exp Cell Res , vol.252 , pp. 464-470
    • Liu, Y.-Y.1    Han, T.-Y.2    Giuliano, A.E.3    Ichikawa, S.4    Hirabayashi, Y.5    Cabot, M.C.6
  • 49
    • 0037203342 scopus 로고    scopus 로고
    • Ceramide in apoptosis: An overview and current perspectives
    • Pettus BJ. Chalfant CE, Hannun YA. Ceramide in apoptosis: An overview and current perspectives. Biochim Biophys Acta 1585:114-125, 2002.
    • (2002) Biochim Biophys Acta , vol.1585 , pp. 114-125
    • Pettus, B.J.1    Chalfant, C.E.2    Hannun, Y.A.3
  • 50
    • 0030856714 scopus 로고    scopus 로고
    • Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide
    • Gudz TI, Tserng K-Y, Hoppel CL. Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide. J Biol Chem 272:24154-24158, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 24154-24158
    • Gudz, T.I.1    Tserng, K.-Y.2    Hoppel, C.L.3
  • 51
    • 0034815640 scopus 로고    scopus 로고
    • Differential sensitivity of breast cancer cells to tumor necrosis factor-alpha: Involvement of protein kinase C
    • Basu A, Mohanty S, Sun B. Differential sensitivity of breast cancer cells to tumor necrosis factor-alpha: Involvement of protein kinase C. Biochem Biophys Res Commun 280:883-891, 2001.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 883-891
    • Basu, A.1    Mohanty, S.2    Sun, B.3
  • 52
    • 0035819885 scopus 로고    scopus 로고
    • Targeting ceramide metabolism: A strategy for overcoming drug resistance
    • Senchenkov A. Litvak DA, Cabot MC. Targeting ceramide metabolism: A strategy for overcoming drug resistance. J Natl Cancer Inst 93:347-357, 2001.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 347-357
    • Senchenkov, A.1    Litvak, D.A.2    Cabot, M.C.3
  • 53
    • 0030948082 scopus 로고    scopus 로고
    • Alteration of the sphingomyelin/ceramide pathway is associated with resistance of human breast carcinoma MCF7 cells to tumor necrosis factor-α-mediated cytotoxicity
    • Cai Z, Bettaieb A, El Mahdani N, Legres LC, Stancou R, Masliah J, Chouaib S. Alteration of the sphingomyelin/ceramide pathway is associated with resistance of human breast carcinoma MCF7 cells to tumor necrosis factor-α-mediated cytotoxicity. J Biol Chem 272:6918-6926, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 6918-6926
    • Cai, Z.1    Bettaieb, A.2    El Mahdani, N.3    Legres, L.C.4    Stancou, R.5    Masliah, J.6    Chouaib, S.7
  • 54
    • 0032837384 scopus 로고    scopus 로고
    • Paradoxical regulation of Bcl-2 family proteins by 17β-oestradiol in human breast cancer cells MCF-7
    • Leung LK, Wang TTY. Paradoxical regulation of Bcl-2 family proteins by 17β-oestradiol in human breast cancer cells MCF-7. Br J Cancer 81:387-392, 1999.
    • (1999) Br J Cancer , vol.81 , pp. 387-392
    • Leung, L.K.1    Wang, T.T.Y.2
  • 57
    • 0034064991 scopus 로고    scopus 로고
    • Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2, and Bcl-xL protein levels
    • Tudor G, Aguilera A, Halverson DO, Liang ND, Sausville EA. Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2, and Bcl-xL protein levels. Cell Death Differ 7:574-586, 2000.
    • (2000) Cell Death Differ , vol.7 , pp. 574-586
    • Tudor, G.1    Aguilera, A.2    Halverson, D.O.3    Liang, N.D.4    Sausville, E.A.5
  • 58
    • 0032854766 scopus 로고    scopus 로고
    • Differential effects of chemotherapeutic agents on the Bcl-2/Bax apoptosis pathway in human breast cancer cell line MCF-7
    • Leung LK, Wang TTY. Differential effects of chemotherapeutic agents on the Bcl-2/Bax apoptosis pathway in human breast cancer cell line MCF-7. Breast Cancer Res Treat 55:73-83, 1999.
    • (1999) Breast Cancer Res Treat , vol.55 , pp. 73-83
    • Leung, L.K.1    Wang, T.T.Y.2
  • 60
    • 0032922468 scopus 로고    scopus 로고
    • Nanomolar range docetaxol treatment sensitizes MCF-7 cells to chemotherapy induced apoptosis, induces G2M arrest and phosphorylates bcl-2
    • Berchem GJ, Bosseler M, Mine N, Avalosse B. Nanomolar range docetaxol treatment sensitizes MCF-7 cells to chemotherapy induced apoptosis, induces G2M arrest and phosphorylates bcl-2. Anticancer Res 19:535-540, 1999.
    • (1999) Anticancer Res , vol.19 , pp. 535-540
    • Berchem, G.J.1    Bosseler, M.2    Mine, N.3    Avalosse, B.4
  • 61
    • 0028979438 scopus 로고
    • Overexpression of Bcl-xs sensitizes MCF-7 cells to chemotherapy-induced apoptosis
    • Sumantran VN, Ealovega MW, Nunez G, Clarke MF, Wicha MS. Overexpression of Bcl-xs sensitizes MCF-7 cells to chemotherapy-induced apoptosis. Cancer Res 55:2507-2510, 1995.
    • (1995) Cancer Res , vol.55 , pp. 2507-2510
    • Sumantran, V.N.1    Ealovega, M.W.2    Nunez, G.3    Clarke, M.F.4    Wicha, M.S.5
  • 62
    • 0032523945 scopus 로고    scopus 로고
    • Modulation of Bcl-2 protein levels by an intracellular anti-Bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7
    • Piche A, Grim J, Rancourt C, Gomez-Navarro J, Reed JC, Curiel DT. Modulation of Bcl-2 protein levels by an intracellular anti-Bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7. Cancer Res 58:2134-2140, 1998.
    • (1998) Cancer Res , vol.58 , pp. 2134-2140
    • Piche, A.1    Grim, J.2    Rancourt, C.3    Gomez-Navarro, J.4    Reed, J.C.5    Curiel, D.T.6
  • 64
    • 0034602188 scopus 로고    scopus 로고
    • Role of BAX in the apoptotic response to anti-cancer agents
    • Zhang L, Yu J, Park BH, Kinzler KW, Vogelstein B. Role of BAX in the apoptotic response to anti-cancer agents. Science 290:989-992, 2000.
    • (2000) Science , vol.290 , pp. 989-992
    • Zhang, L.1    Yu, J.2    Park, B.H.3    Kinzler, K.W.4    Vogelstein, B.5
  • 65
    • 0027164144 scopus 로고
    • High expression of Bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy
    • Campos L, Roualt JP, Sabido O. High expression of Bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy. Blood 81:3091-3096, 1993.
    • (1993) Blood , vol.81 , pp. 3091-3096
    • Campos, L.1    Roualt, J.P.2    Sabido, O.3
  • 67
    • 0034720484 scopus 로고    scopus 로고
    • Anchorage-independent activation of mitogen-activated protein kinase through phosphatidylinositol-3 kinase by insulin-like growth factor I
    • Suzuki K, Takahashi K. Anchorage-independent activation of mitogen-activated protein kinase through phosphatidylinositol-3 kinase by insulin-like growth factor I. Biochem Biophys Res Commun 272:111-115, 2000.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 111-115
    • Suzuki, K.1    Takahashi, K.2
  • 68
    • 0034993857 scopus 로고    scopus 로고
    • Activation of adenosine deaminase in MCF-7 cells through IGF-estrogen receptor alpha crosstalk
    • Xie W, Duan R, Safe S. Activation of adenosine deaminase in MCF-7 cells through IGF-estrogen receptor alpha crosstalk. J Mol Endocrinol 26:217-228, 2001.
    • (2001) J Mol Endocrinol , vol.26 , pp. 217-228
    • Xie, W.1    Duan, R.2    Safe, S.3
  • 69
    • 0034113153 scopus 로고    scopus 로고
    • Novel function PI 3-kinase antagonists inhibit cell growth and tumorigenicity in human cancer cell lines
    • Razzini G, Berrie CP, Vignati S, Briginni M, Mascetta G, Brancaccio A, Falasca M. Novel function PI 3-kinase antagonists inhibit cell growth and tumorigenicity in human cancer cell lines. FASEB J 14:1179-1187, 2000.
    • (2000) FASEB J , vol.14 , pp. 1179-1187
    • Razzini, G.1    Berrie, C.P.2    Vignati, S.3    Briginni, M.4    Mascetta, G.5    Brancaccio, A.6    Falasca, M.7
  • 70
    • 0036185848 scopus 로고    scopus 로고
    • The protein kinase B/Akt signaling pathway in human malignancy
    • Nicholson KM, Anderson NG. The protein kinase B/Akt signaling pathway in human malignancy. Cell Signal 14:381-395, 2002.
    • (2002) Cell Signal , vol.14 , pp. 381-395
    • Nicholson, K.M.1    Anderson, N.G.2
  • 71
    • 0035889120 scopus 로고    scopus 로고
    • Transformation of interleukin-3-dependent cells without participation of Stat5/bcl-xL: Cooperation of akt with raf/erk leads to p65 nuclear factor κB-mediated antiapoptosis involving c-IAP 2
    • Gelfanov VM, Burgess GS, Litz-Jackson S, King AJ, Marshall MS, Nakshatri H, Boswell HS. Transformation of interleukin-3-dependent cells without participation of Stat5/bcl-xL: Cooperation of akt with raf/erk leads to p65 nuclear factor κB-mediated antiapoptosis involving c-IAP2. Blood 98:2508-2517, 2001.
    • (2001) Blood , vol.98 , pp. 2508-2517
    • Gelfanov, V.M.1    Burgess, G.S.2    Litz-Jackson, S.3    King, A.J.4    Marshall, M.S.5    Nakshatri, H.6    Boswell, H.S.7
  • 72
    • 0032209522 scopus 로고    scopus 로고
    • Signaling through protein kinase C
    • Toker A. Signaling through protein kinase C. Frontiers Biosci 3: dl134-dl147, 1998.
    • (1998) Frontiers Biosci , vol.3
    • Toker, A.1
  • 74
  • 75
    • 0034737436 scopus 로고    scopus 로고
    • Cross-talk between phosphatidylinositol 3-kinase and sphingomyelinase pathways as a mechanism for cell survival/death decisions
    • Burow ME, Collins-Burow BM, Weldon CB, Klippel A, McLachlan JA, Clejan S, Beckman BS. Cross-talk between phosphatidylinositol 3-kinase and sphingomyelinase pathways as a mechanism for cell survival/death decisions. J Biol Chem 275:9628-9635, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 9628-9635
    • Burow, M.E.1    Collins-Burow, B.M.2    Weldon, C.B.3    Klippel, A.4    McLachlan, J.A.5    Clejan, S.6    Beckman, B.S.7
  • 77
    • 0033214236 scopus 로고    scopus 로고
    • Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
    • Lin Y, Devin A, Rodriguez Y, Liu Z-G. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 13:2514-2526, 1999.
    • (1999) Genes Dev , vol.13 , pp. 2514-2526
    • Lin, Y.1    Devin, A.2    Rodriguez, Y.3    Liu, Z.-G.4
  • 80
    • 18544396176 scopus 로고    scopus 로고
    • Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappa B, and cyclic AMP response element binding with acquired resistance to Fasodex (ICI 182,780)
    • Gu Z, Lee RY, Skaar TC, Bouker KB, Welch JN, Lu J, Liu A, Zhu Y, Davis N, et al. Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappa B, and cyclic AMP response element binding with acquired resistance to Fasodex (ICI 182,780). Cancer Res 62:3428-3437, 2000.
    • (2000) Cancer Res , vol.62 , pp. 3428-3437
    • Gu, Z.1    Lee, R.Y.2    Skaar, T.C.3    Bouker, K.B.4    Welch, J.N.5    Lu, J.6    Liu, A.7    Zhu, Y.8    Davis, N.9
  • 81
    • 0036675104 scopus 로고    scopus 로고
    • Identification of mitogen-activated protein kinase kinase as a chemoresistant pathway in MCF-7 cells by using gene expression microarray
    • Weldon CB, Scandurro AB, Rolfe KW, Clayton JL, Elliott S, Butler NN, Melnik LI, Alam J, McLachlan JA, et al. Identification of mitogen-activated protein kinase kinase as a chemoresistant pathway in MCF-7 cells by using gene expression microarray. Surgery 132:293-301, 2002.
    • (2002) Surgery , vol.132 , pp. 293-301
    • Weldon, C.B.1    Scandurro, A.B.2    Rolfe, K.W.3    Clayton, J.L.4    Elliott, S.5    Butler, N.N.6    Melnik, L.I.7    Alam, J.8    McLachlan, J.A.9


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