Hydrogen sulfide-releasing aspirin suppresses NF-κB signaling in estrogen receptor negative breast cancer cells in vitro and in vivo

Biochemical Pharmacology

Volumn 83, Issue 6, 2012, Pages 723-732

  Chattopadhyay, Mitali ^a   Kodela, Ravinder ^a   Nath, Niharika ^b   Barsegian, Arpine ^a   Boring, Daniel ^c   Kashfi, Khosrow ^a  

^a CITY UNIVERSITY OF NEW YORK MEDICAL SCHOOL   (United States)

^b NEW YORK INSTITUTE OF TECHNOLOGY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Chemoprevention; Estrogen receptor negative breast cancer; Hydrogen sulfide; NF B; Thioredoxin reductase

Indexed keywords

[4 (5 THIOXO 5H 1, 2 DITHIOL 3 YL)PHENYL 2 ACETOXYBENZOATE]; ACETYLSALICYLIC ACID; ESTROGEN RECEPTOR; HYDROGEN SULFIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE; THIOREDOXIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CANCER SIZE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; TRIPLE NEGATIVE BREAST CANCER; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; ASPIRIN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; HUMANS; HYDROGEN SULFIDE; MICE; NF-KAPPA B; REACTIVE OXYGEN SPECIES; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; THIONES; THIOREDOXIN-DISULFIDE REDUCTASE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84857060149     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.12.019     Document Type: Article

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