Selective cytotoxicity, inhibition of cell cycle progression, and induction of apoptosis in human breast cancer cells by sesquiterpenoids from Inula lineariifolia Turcz.

European Journal of Medicinal Chemistry

Volumn 68, Issue , 2013, Pages 473-481

  Qin, Jiang Jiang ^a,c   Jin, Hui Zi ^a   Huang, Ying ^a   Zhang, Shou De ^a   Shan, Lei ^b   Voruganti, Sukesh ^c   Nag, Subhasree ^c   Wang, Wei ^c   Zhang, Wei Dong ^a,b   Zhang, Ruiwen ^c  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Apoptosis; Breast cancer; Cell cycle arrest; Cytotoxicity; Inula lineariifolia Turcz.; Sesquiterpenoid

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN; LINEARIIFOLIANOID; PACLITAXEL; SESQUITERPENOID; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER INHIBITION; CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INULA; NUCLEAR OVERHAUSER EFFECT; SPECTROSCOPY; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

APOPTOSIS; BREAST CANCER; CELL CYCLE ARREST; CYTOTOXICITY; GNGQKLZFBUPHJG-XISWFLCMSA-N; INULA LINEARIIFOLIA TURCZ.; JRTIKBMBXBPGNG-XFGMNWCASA-N; MBMTVBZMAJEBHZ-RUQFOMCVSA-N; OJVIJEPDCXTKTE-SJRFUVFFSA-N; RBLYUGWIFLXCPD-CDWXYHGHSA-N; RYPWQIGVZVKJLS-OOUKEXCNSA-N; SESQUITERPENOID; WCZBMGWSWYHCAA-PDNFSXIVSA-N;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CRYSTALLOGRAPHY, X-RAY; FEMALE; HUMANS; INULA; MOLECULAR STRUCTURE; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; TERPENES;

EID: 84883715434     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.07.018     Document Type: Article

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