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Volumn 38, Issue 1, 2010, Pages 76-87

Roles for inflammation and regulatory T cells in colon cancer

Author keywords

Colon cancer; Division of Comparative; Gut bacteria; Inflammation; TREG cells

Indexed keywords

APC PROTEIN; CD4 ANTIGEN; ETANERCEPT; INFLIXIMAB; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; K RAS PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; RAG2 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 77952305365     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623309354110     Document Type: Review
Times cited : (93)

References (81)
  • 1
    • 1442347508 scopus 로고    scopus 로고
    • American Cancer Society (ACS). U.S. Cancer Fact and Figures. ACS, Atlanta, GA
    • American Cancer Society (ACS). (2004). Cancer facts and figures. U.S. Cancer Fact and Figures. ACS, Atlanta, GA.
    • (2004) Cancer Facts and Figures
  • 2
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman, C., Mauze, S., Leach, M. W., Coffman, R. L., and Powrie, F. (1999). An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med 190, 995-1004.
    • (1999) J Exp Med , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 4
    • 0035133050 scopus 로고    scopus 로고
    • Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells
    • Badache, A., and Hynes, N. E. (2001). Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells. Cancer Res 61, 383-391
    • (2001) Cancer Res , vol.61 , pp. 383-391
    • Badache, A.1    Hynes, N.E.2
  • 5
    • 4644335311 scopus 로고    scopus 로고
    • Cancer: An inflammatory link
    • Balkwill, F., and Coussens, L. M. (2001). Cancer: An inflammatory link. Nature 431, 405-406
    • (2001) Nature , vol.431 , pp. 405-406
    • Balkwill, F.1    Coussens, L.M.2
  • 6
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill, F., and Mantovani, A. (2001). Inflammation and cancer: Back to Virchow? Lancet 357, 539-545
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 7
    • 17644394616 scopus 로고    scopus 로고
    • Smoldering and polarized inflammation in the initiation and promotion of malignant disease
    • Balkwill, F., Charles, K. A., and Mantovani, A. (2005). Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 7, 211-217
    • (2005) Cancer Cell , vol.7 , pp. 211-217
    • Balkwill, F.1    Charles, K.A.2    Mantovani, A.3
  • 9
    • 16844369607 scopus 로고    scopus 로고
    • Natural regulatory T cells in infectious disease
    • Belkaid, Y., and Rouse, B. T. (2005). Natural regulatory T cells in infectious disease. Nat Immunol 6, 353-360
    • (2005) Nat Immunol , vol.6 , pp. 353-360
    • Belkaid, Y.1    Rouse, B.T.2
  • 11
    • 13244290058 scopus 로고    scopus 로고
    • IL-12- and IL-23-induced T helper cell subsets: Birds of the same feather flock together
    • Bettelli, E., and Kuchroo, V. K. (2007). IL-12- and IL-23-induced T helper cell subsets: Birds of the same feather flock together. J Exp Med 201, 169-171
    • (2007) J Exp Med , vol.201 , pp. 169-171
    • Bettelli, E.1    Kuchroo, V.K.2
  • 12
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., and Kuchroo, V. K. (2006). Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441, 235-238
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 13
    • 35348960243 scopus 로고    scopus 로고
    • Th17: The third member of the effector T cell trilogy
    • Bettelli, E., Korn, T., and Kuchroo, V. K. (2007). Th17: The third member of the effector T cell trilogy. Curr Opin Immunol 19, 652-657
    • (2007) Curr Opin Immunol , vol.19 , pp. 652-657
    • Bettelli, E.1    Korn, T.2    Kuchroo, V.K.3
  • 14
    • 34248572345 scopus 로고    scopus 로고
    • T(H)-17 cells in the circle of immunity and autoimmunity
    • Bettelli, E., Oukka, M., and Kuchroo, V. K. (2007). T(H)-17 cells in the circle of immunity and autoimmunity. Nat Immunol 8, 345-350
    • (2007) Nat Immunol , vol.8 , pp. 345-350
    • Bettelli, E.1    Oukka, M.2    Kuchroo, V.K.3
  • 16
    • 58649100056 scopus 로고    scopus 로고
    • Inflammation and cancer: IL-6 and STAT3 complete the link
    • Bromberg, J., and Wang, T. C. (2009). Inflammation and cancer: IL-6 and STAT3 complete the link. Cancer Cell 15, 79-80.
    • (2009) Cancer Cell , vol.15 , pp. 79-80
    • Bromberg, J.1    Wang, T.C.2
  • 17
    • 0016779932 scopus 로고
    • The effects of long-term estrogen administration to women following hysterectomy
    • Burch, J. C., Byrd, B. F., and Vaughn, W. K. (1975). The effects of long-term estrogen administration to women following hysterectomy. Front Horm Res 3, 208-214
    • (1975) Front Horm Res , vol.3 , pp. 208-214
    • Burch, J.C.1    Byrd, B.F.2    Vaughn, W.K.3
  • 18
    • 58249092189 scopus 로고    scopus 로고
    • Getting the bugs out of the immunesystem: Do bacterial microbiota "fix" intestinal T cell responses?
    • Chow, J., and Mazmanian, S. K. (2009). Getting the bugs out of the immunesystem: Do bacterial microbiota "fix" intestinal T cell responses? Cell Host Microbe 5, 8-12.
    • (2009) Cell Host Microbe , vol.5 , pp. 8-12
    • Chow, J.1    Mazmanian, S.K.2
  • 19
    • 35548950221 scopus 로고    scopus 로고
    • Regulatory-T-cell inhibition versus depletion: The right choice in cancer immunotherapy
    • Colombo, M. P., and Piconese, S. (2007). Regulatory-T-cell inhibition versus depletion: The right choice in cancer immunotherapy. Nat Rev Cancer 7, 880-887
    • (2007) Nat Rev Cancer , vol.7 , pp. 880-887
    • Colombo, M.P.1    Piconese, S.2
  • 20
    • 0037360706 scopus 로고    scopus 로고
    • Helicobacter pylori infection and gastric cancer
    • Correa, P. (2003). Helicobacter pylori infection and gastric cancer. Cancer Epidemiol Biomarkers Prev 12, 238s-41s.
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12
    • Correa, P.1
  • 21
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens, L. M., and Werb, Z. (1999). Inflammation and cancer. Nature 420, 860-867
    • (1999) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 23
    • 44749092510 scopus 로고    scopus 로고
    • Regulatory T cells and treatment of cancer
    • Curiel, T. J. (2008). Regulatory T cells and treatment of cancer. Curr Opin Immunol 20, 241-246
    • (2008) Curr Opin Immunol , vol.20 , pp. 241-246
    • Curiel, T.J.1
  • 25
    • 3543140687 scopus 로고    scopus 로고
    • Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy
    • Ehrenstein, M. R., Evans, J. G., Singh, A., Moore, S., Warnes, G., Isenberg, D. A., and Mauri, C. (2004). Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy. J Exp Med 200, 277-285
    • (2004) J Exp Med , vol.200 , pp. 277-285
    • Ehrenstein, M.R.1    Evans, J.G.2    Singh, A.3    Moore, S.4    Warnes, G.5    Isenberg, D.A.6    Mauri, C.7
  • 27
    • 0037112436 scopus 로고    scopus 로고
    • Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice
    • Engle, S. J., Ormsby, I., Pawlowski, S., Boivin, G. P., Croft, J., Balish, E., and Doetschman, T. (2002). Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice. Cancer Res 62, 6362-6366
    • (2002) Cancer Res , vol.62 , pp. 6362-6366
    • Engle, S.J.1    Ormsby, I.2    Pawlowski, S.3    Boivin, G.P.4    Croft, J.5    Balish, E.6    Doetschman, T.7
  • 32
    • 20144375359 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice
    • Erdman, S. E., Sohn, J. J., Rao, V. P., Nambiar, P. R., Ge, Z., Fox, J. G., and Schauer, D. B. (2005). CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice. Cancer Res 65, 3998-4004.
    • (2005) Cancer Res , vol.65 , pp. 3998-4004
    • Erdman, S.E.1    Sohn, J.J.2    Rao, V.P.3    Nambiar, P.R.4    Ge, Z.5    Fox, J.G.6    Schauer, D.B.7
  • 34
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon, E. R., and Vogelstein, B. (1990). A genetic model for colorectal tumorigenesis. Cell 61, 759-767
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 35
    • 33845981808 scopus 로고    scopus 로고
    • Inflammation, atrophy, and gastric cancer
    • Fox, J. G., and Wang, T. C. (2007). Inflammation, atrophy, and gastric cancer. J Clin Invest 117, 60-69.
    • (2007) J Clin Invest , vol.117 , pp. 60-69
    • Fox, J.G.1    Wang, T.C.2
  • 36
    • 0034027476 scopus 로고    scopus 로고
    • Concurrent enteric helminth infection modulates inflammation and gastric immune responses and reduces helicobacter-induced gastric atrophy
    • Fox, J. G., Beck, P., Dangler, C. A.,Whary, M. T.,Wang, T. C., Shi, H. N., and Nagler-Anderson, C. (2000). Concurrent enteric helminth infection modulates inflammation and gastric immune responses and reduces helicobacter-induced gastric atrophy. Nat Med 6, 536-542
    • (2000) Nat Med , vol.6 , pp. 536-542
    • Fox, J.G.1    Beck, P.2    Dangler, C.A.3    Whary, M.T.4    Wang, T.C.5    Shi, H.N.6    Nagler-Anderson, C.7
  • 38
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • Greten, F. R., Eckmann, L., Greten, T. F., Park, J. M., Li, Z. W., Egan, L. J., Kagnoff, M. F., and Karin, M. (2004). IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118, 285-296
    • (2004) Cell , vol.118 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3    Park, J.M.4    Li, Z.W.5    Egan, L.J.6    Kagnoff, M.F.7    Karin, M.8
  • 39
    • 0035866802 scopus 로고    scopus 로고
    • Intestinal microflora are necessary for development of spontaneous adenocarcinoma of the large intestine in T-cell receptor beta chain and p53 double-knockout mice
    • Kado, S., Uchida, K., Funabashi, H., Iwata, S., Nagata, Y., Ando, M., Onoue, M., Matsuoka. Y., Ohwaki, M., and Morotomi, M. (2001). Intestinal microflora are necessary for development of spontaneous adenocarcinoma of the large intestine in T-cell receptor beta chain and p53 double-knockout mice. Cancer Res 61, 2395-2398
    • (2001) Cancer Res , vol.61 , pp. 2395-2398
    • Kado, S.1    Uchida, K.2    Funabashi, H.3    Iwata, S.4    Nagata, Y.5    Ando, M.6    Onoue, M.7    Matsuoka., Y.8    Ohwaki, M.9    Morotomi, M.10
  • 40
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin, M. (2006). Nuclear factor-kappaB in cancer development and progression. Nature 441, 431-436
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 42
    • 0034031128 scopus 로고    scopus 로고
    • Review of colorectal cancer and its metastases in rodent models: Comparative aspects with those in humans
    • Kobaek-Larsen, M., Thorup, I., Diederichsen, A., Fenger, C., and Hoitinga, M. R. (2000). Review of colorectal cancer and its metastases in rodent models: Comparative aspects with those in humans. Comp Med 50, 16-26.
    • (2000) Comp Med , vol.50 , pp. 16-26
    • Kobaek-Larsen, M.1    Thorup, I.2    Diederichsen, A.3    Fenger, C.4    Hoitinga, M.R.5
  • 43
    • 55149094300 scopus 로고    scopus 로고
    • Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells
    • Koenen, H. J., Smeets, R. L., Vink, P. M., van Rijssen, E., Boots, A. M., and Joosten, I. (2008). Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 112, 2340-2352
    • (2008) Blood , vol.112 , pp. 2340-2352
    • Koenen, H.J.1    Smeets, R.L.2    Vink, P.M.3    Van Rijssen, E.4    Boots, A.M.5    Joosten, I.6
  • 44
    • 39449087338 scopus 로고    scopus 로고
    • Th17 cells: Effector T cells with inflammatory properties
    • Korn, T., Oukka, M., Kuchroo, V., and Bettelli, E. (2007). Th17 cells: Effector T cells with inflammatory properties. Semin Immunol 19, 362-371
    • (2007) Semin Immunol , vol.19 , pp. 362-371
    • Korn, T.1    Oukka, M.2    Kuchroo, V.3    Bettelli, E.4
  • 47
  • 49
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • Lewis, C. E., and Pollard, J. W. (2006). Distinct role of macrophages in different tumor microenvironments. Cancer Res 66, 605-612
    • (2006) Cancer Res , vol.66 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 50
    • 0141856647 scopus 로고    scopus 로고
    • Gastric adenocarcinoma
    • (J. J. Goedert, ed.). Humana Press, Totowa, NJ
    • Ley, C., and Parsonnet, J. (2000). Gastric adenocarcinoma. In Infectious Causes of Cancer (J. J. Goedert, ed.), pp. 389-410. Humana Press, Totowa, NJ.
    • (2000) Infectious Causes of Cancer , pp. 389-410
    • Ley, C.1    Parsonnet, J.2
  • 51
    • 33947283114 scopus 로고    scopus 로고
    • Oral contraceptives, reproductive factors, and risk of colorectal cancer among women in a prospective cohort study
    • Lin, J., Zhang, S. M., Cook, N. R., Manson, J. E., Buring, J. E., and Lee, I. M. (2007). Oral contraceptives, reproductive factors, and risk of colorectal cancer among women in a prospective cohort study. Am J Epidemiol 165, 794-801.
    • (2007) Am J Epidemiol , vol.165 , pp. 794-801
    • Lin, J.1    Zhang, S.M.2    Cook, N.R.3    Manson, J.E.4    Buring, J.E.5    Lee, I.M.6
  • 52
    • 0035681366 scopus 로고    scopus 로고
    • IL-6 inhibits apoptosis and retains oxidative DNA lesions in human gastric cancer AGS cells through up-regulation of anti-apoptotic gene mcl-1
    • Lin, M. T., Juan, C. Y., Chang, K. J., Chen, W. J., and Kuo, M. L. (2001). IL-6 inhibits apoptosis and retains oxidative DNA lesions in human gastric cancer AGS cells through up-regulation of anti-apoptotic gene mcl-1. Carcinogenesis 22, 1947-1953
    • (2001) Carcinogenesis , vol.22 , pp. 1947-1953
    • Lin, M.T.1    Juan, C.Y.2    Chang, K.J.3    Chen, W.J.4    Kuo, M.L.5
  • 53
    • 0037243827 scopus 로고    scopus 로고
    • CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
    • Maloy, K. J., Salaun, L., Cahill, R., Dougan, G., Saunders, N. J., and Powrie, F. (2003). CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J Exp Med 197, 111-119
    • (2003) J Exp Med , vol.197 , pp. 111-119
    • Maloy, K.J.1    Salaun, L.2    Cahill, R.3    Dougan, G.4    Saunders, N.J.5    Powrie, F.6
  • 54
    • 0036169389 scopus 로고    scopus 로고
    • COX-2: A target for colon cancer prevention
    • Marnett, L. J., and DuBois, R. N. (2002). COX-2: A target for colon cancer prevention. Annu Rev Pharmacol Toxicol 42, 55-80.
    • (2002) Annu Rev Pharmacol Toxicol , vol.42 , pp. 55-80
    • Marnett, L.J.1    Dubois, R.N.2
  • 55
    • 44449106055 scopus 로고    scopus 로고
    • A microbial symbiosis factor prevents intestinal inflammatory disease
    • Mazmanian, S. K., Round, J. L., and Kasper, D. L. (2008). A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 453, 620-625
    • (2008) Nature , vol.453 , pp. 620-625
    • Mazmanian, S.K.1    Round, J.L.2    Kasper, D.L.3
  • 57
    • 0032535002 scopus 로고    scopus 로고
    • Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: Role of interleukin-6 and macrophage colony-stimulating factor
    • Menetrier-Caux, C., Montmain, G., Dieu, M. C., Bain, C., Favrot, M. C., Caux, C., and Blay, J. Y. (1998). Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: Role of interleukin-6 and macrophage colony-stimulating factor. Blood 92, 4778-4791
    • (1998) Blood , vol.92 , pp. 4778-4791
    • Menetrier-Caux, C.1    Montmain, G.2    Dieu, M.C.3    Bain, C.4    Favrot, M.C.5    Caux, C.6    Blay, J.Y.7
  • 58
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser, A. R., Pitot, H. C., and Dove, W. F. (1990). A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247, 322-324
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1    Pitot, H.C.2    Dove, W.F.3
  • 59
    • 34447327216 scopus 로고    scopus 로고
    • Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
    • Naugler, W. E., Sakurai, T., Kim, S., Maeda, S., Kim, K., Elsharkawy, A. M., and Karin, M. (2007). Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317, 121-124
    • (2007) Science , vol.317 , pp. 121-124
    • Naugler, W.E.1    Sakurai, T.2    Kim, S.3    Maeda, S.4    Kim, K.5    Elsharkawy, A.M.6    Karin, M.7
  • 60
    • 33749072534 scopus 로고    scopus 로고
    • Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress
    • Pace, T. W., Mletzko, T. C., Alagbe, O., Musselman, D. L., Nemeroff, C. B., Miller, A. H., and Heim, C. M. (2006). Increased stress-induced inflammatory responses in male patients with major depression and increased early life stress. Am J Psychiatry 163, 1630-1633
    • (2006) Am J Psychiatry , vol.163 , pp. 1630-1633
    • Pace, T.W.1    Mletzko, T.C.2    Alagbe, O.3    Musselman, D.L.4    Nemeroff, C.B.5    Miller, A.H.6    Heim, C.M.7
  • 62
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinomas
    • Peek, R. M., Jr., and Blaser, M. J. (2002). Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer 2, 28-37.
    • (2002) Nat Rev Cancer , vol.2 , pp. 28-37
    • Peek Jr., R.M.1    Blaser, M.J.2
  • 63
    • 22644436705 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs for the prevention and treatment of cancer
    • Pereg, D., and Lishner, M. (2005). Non-steroidal anti-inflammatory drugs for the prevention and treatment of cancer. J Intern Med 258, 115-123
    • (2005) J Intern Med , vol.258 , pp. 115-123
    • Pereg, D.1    Lishner, M.2
  • 64
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard, J. W. (2004). Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 4, 71-78.
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 68
    • 0037436121 scopus 로고    scopus 로고
    • Immunology Regulating the regulators
    • Powrie, F., and Maloy, K. J. (2003). Immunology. Regulating the regulators. Science 299, 1030-1031
    • (2003) Science , vol.299 , pp. 1030-1031
    • Powrie, F.1    Maloy, K.J.2
  • 70
    • 33847041537 scopus 로고    scopus 로고
    • Breast cancer: Should gastrointestinal bacteria be on our radar screen?
    • Rao, V. P., Poutahidis, T., Fox, J. G., and Erdman, S. E. (2007). Breast cancer: Should gastrointestinal bacteria be on our radar screen? Cancer Res 67, 847-850
    • (2007) Cancer Res , vol.67 , pp. 847-850
    • Rao, V.P.1    Poutahidis, T.2    Fox, J.G.3    Erdman, S.E.4
  • 71
    • 33747481384 scopus 로고    scopus 로고
    • Innate immune inflammatory response against enteric bacteria Helicobacter hepaticus induces mammary adenocarcinoma in mice
    • Rao, V. P., Poutahidis, T., Ge, Z., Nambiar, P. R., Boussahmain, C., Wang, Y. Y., Horwitz, B. H., Fox, J. G., and Erdman, S. E. (2006). Innate immune inflammatory response against enteric bacteria Helicobacter hepaticus induces mammary adenocarcinoma in mice. Cancer Res 66, 7395-7400.
    • (2006) Cancer Res , vol.66 , pp. 7395-7400
    • Rao, V.P.1    Poutahidis, T.2    Ge, Z.3    Nambiar, P.R.4    Boussahmain, C.5    Wang, Y.Y.6    Horwitz, B.H.7    Fox, J.G.8    Erdman, S.E.9
  • 72
    • 31544451792 scopus 로고    scopus 로고
    • Pro-inflammatory CD4+ CD45RB(hi) lymphocytes promote mammary and intestinal carcinogenesis in Apc(Min/+) mice
    • Rao, V. P., Poutahidis, T., Ge, Z., Nambiar, P. R., Horwitz, B. H., Fox, J. G., and Erdman, S. E. (2006). Pro-inflammatory CD4+ CD45RB(hi) lymphocytes promote mammary and intestinal carcinogenesis in Apc(Min/+) mice. Cancer Res 66, 57-61.
    • (2006) Cancer Res , vol.66 , pp. 57-61
    • Rao, V.P.1    Poutahidis, T.2    Ge, Z.3    Nambiar, P.R.4    Horwitz, B.H.5    Fox, J.G.6    Erdman, S.E.7
  • 74
    • 58249089749 scopus 로고    scopus 로고
    • Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer
    • Salama, P., Phillips, M., Grieu, F., Morris, M., Zeps, N., Joseph, D., Platell, C.,and Iacopetta, B. (2009). Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer. J Clin Oncol 27, 186-192
    • (2009) J Clin Oncol , vol.27 , pp. 186-192
    • Salama, P.1    Phillips, M.2    Grieu, F.3    Morris, M.4    Zeps, N.5    Joseph, D.6    Platell, C.7    Iacopetta, B.8
  • 76
    • 0020569337 scopus 로고
    • Nonsteroid antiinflammatory drugs and tamoxifen for desmoid tumors and carcinoma of the stomach
    • Waddell, W. R., Gerner, R. E., and Reich, M. P. (1983). Nonsteroid antiinflammatory drugs and tamoxifen for desmoid tumors and carcinoma of the stomach. J Surg Oncol 22, 197-211.
    • (1983) J Surg Oncol , vol.22 , pp. 197-211
    • Waddell, W.R.1    Gerner, R.E.2    Reich, M.P.3
  • 77
    • 0027988869 scopus 로고
    • Chronic active hepatitis in mice caused by Helicobacter hepaticus
    • Ward, J. M., Anver, M. R., Haines, D. C., and Benveniste, R. E. (1994). Chronic active hepatitis in mice caused by Helicobacter hepaticus. Am J Pathol 145, 959-968
    • (1994) Am J Pathol , vol.145 , pp. 959-968
    • Ward, J.M.1    Anver, M.R.2    Haines, D.C.3    Benveniste, R.E.4
  • 78
    • 0029873909 scopus 로고    scopus 로고
    • Inflammatory large bowel disease in immunodeficient mice naturally infected with Helicobacter hepaticus
    • Ward, J. M., Anver, M. R., Haines, D. C., Melhorn, J. M., Gorelick, P., Yan, L., and Fox, J. G. (1996). Inflammatory large bowel disease in immunodeficient mice naturally infected with Helicobacter hepaticus. Lab Anim Sci 46, 15-20.
    • (1996) Lab Anim Sci , vol.46 , pp. 15-20
    • Ward, J.M.1    Anver, M.R.2    Haines, D.C.3    Melhorn, J.M.4    Gorelick, P.5    Yan, L.6    Fox, J.G.7
  • 79
    • 0037136586 scopus 로고    scopus 로고
    • Eat dirt-the hygiene hypothesis and allergic diseases
    • Weiss, S. T. (2002). Eat dirt-the hygiene hypothesis and allergic diseases. N Engl J Med 347, 930-931
    • (2002) N Engl J Med , vol.347 , pp. 930-931
    • Weiss, S.T.1
  • 80
    • 0032719646 scopus 로고    scopus 로고
    • Helicobacter pylori: From the benign to the malignant
    • Williams, M. P., and Pounder, R. E. (1999). Helicobacter pylori: From the benign to the malignant. Am J Gastroenterol 94 (), S11-16.
    • (1999) Am J Gastroenterol , vol.94
    • Williams, M.P.1    Pounder, R.E.2
  • 81
    • 0035495857 scopus 로고    scopus 로고
    • The germless theory of allergic disease: Revisiting the hygiene hypothesis
    • Wills-Karp, M., Santeliz, J., and Karp, C. L. (2001). The germless theory of allergic disease: Revisiting the hygiene hypothesis. Nat Rev Immunol 1, 69-75.
    • (2001) Nat Rev Immunol , vol.1 , pp. 69-75
    • Wills-Karp, M.1    Santeliz, J.2    Karp, C.L.3


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