Sulindac inhibits activation of the NF-κB pathway

Journal of Biological Chemistry

Volumn 274, Issue 38, 1999, Pages 27307-27314

  Yamamoto, Yumi ^a   Yin, Min Jean ^a   Lin, Keng Mean ^a   Gaynor, Richard B ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SULINDAC; SULINDAC SULFIDE; SULINDAC SULFONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CANCER PREVENTION; CELL PROLIFERATION; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BACULOVIRIDAE; COS CELLS; GENE EXPRESSION REGULATION; HT29 CELLS; HUMANS; I-KAPPA B KINASE; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; SULINDAC;

EID: 0033578879     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.38.27307     Document Type: Article

References (60)

1. Baeuerle, P. A., and Baltimore, D. (1996) Cell 87, 13-20
2. Baldwin, A. S. (1996) Annu. Rev. Immunol. 14, 649-681
3. Lu, X., Xie, W., Reed, D., Bradshaw, W. S., and Simmons, D. L. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7961-7965
4. Wang, C. Y., Mayo, M. W., Korneluk, R. G., Goeddel, D. V., and Baldwin, A. S., Jr. (1998) Science 281, 1680-1683
5. Beg, A. A., Sha, W. C., Bronson, R. T., Ghosh, S., and Baltimore, D. (1995) Nature 376, 167-170
6. Chu, Z.-L., McKinsey, T. A., Liu, L., Gentry, J. J., Malim, M. H., and Ballard, D. W. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 10057-10062
7. Wu, M., Lee, H., Bellas, R. E., Schauer, S. L., Arsura, M., Katz, D., FitzGerald, M. J., Rothstein, T. L., Sherr, D. H., and Sonenshein, G. E. (1996) EMBO J. 15, 4682-4690
8. Sovak, M. A., Bellas, R. E., Kim, D. W., Zanieski, G. J., Rogers, A. E., Traish, A. M., and Sonenshein, G. E. (1997) J. Clin. Invest. 100, 2952-2960
9. Nakshatri, H., Bhat-Nakshatri, P., Martin, D. A., Goulet, R. J., Jr., and Sledge, G. W., Jr. (1997) Mol. Cell. Biol. 17, 3629-3639
10. Beg, A. A., Finco, T. S., Nantermet, P. V., and Baldwin, A. S. J. (1993) Mol. Cell. Biol. 13, 3301-3310
11. Beg, A. A., Ruben, S. M., Scheinman, R. I., Haskill, S., Rosen, C. A., and Baldwin, A. S., Jr. (1992) Genes Dev. 6, 1899-1913
12. Didonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., and Karin, M. (1997) Nature 388, 548-554
13. Mercurio, F., Zhu, H., Murray, B. W., Shevchenko, A., Bennett, B. L., Li, J., Young, D. B., Barbosa, M., and Mann, M. (1997) Science 278, 860-866
14. Regnier, C. H., Song, H. Y., Gao, X., Goeddel, D. V., Cao, Z., and Rothe, M. (1997) Cell 90, 373-383
15. Woronicz, J. D., Gao, X., Cao, Z., Rothe, M., and Goeddel, D. V. (1997) Science 278, 866-869
16. Zandi, E., Rothwarf, D. M., Delhase, M., Hayakawa, M., and Karin, M. (1997) Cell 91, 243-252
17. Alkalay, I. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 10599-10603
18. Brockman, J. A., Scherer, D. C., MsKinsey, T. A., Hall, S. M., Qi, X., Lee, W. Y., and Ballard, D. W. (1995) Mol. Cell. Biol. 15, 2809-2818
19. Brown, K., Gerstberger, S., Carlson, L., Fransozo, G., and Siebenlist, U. (1995) Science 267, 1485-1488
20. Chen, Z., Hagler, J., Palombella, V. J., Melandri, F., Scherer, D., Ballard, D., and Maniatis, T. (1995) Genes Dev. 9, 1586-1597
21. Didonato, J. A., Mercurio, F., and Karin, M. (1995) Mol. Cell. Biol. 15, 1302-1311
22. Traenckner, E. B. M., Pahl, H. L., Henkel, T., Schmidt, K. N., Wilk, S., and Baeuerle, P. A. (1995) EMBO J. 14, 2876-2883
23. Whiteside, S. T., Ernst, M. K., LeBail, O., Laurent-Winter, C., Rice, N., and Israel, A. (1995) Mol. Cell. Biol. 15, 5339-5345
24. Grilli, M., Pizzi, M., Memo, M., and Spano, P. (1996) Science 274, 1383-1385
25. Kopp, E., and Ghosh, S. (1994) Science 265, 956-959
26. Yin, M.-J., Yamamoto, Y., and Gaynor, R. B. (1998) Nature 396, 77-80
27. Thun, M. J., Namboodiri, M. M., and Heath, C. W., Jr. (1991) N. Engl. J. Med. 325, 1593-1596
28. Suh, O., Mettlin, C., and Petrelli, N. J. (1993) Cancer (Phila.) 72, 1171-1177
29. Giovannucci, E., Rimm, E. B., Stampfer, M. J., Colditz, G. A., Ascherio, A., and Willett, W. C. (1994) Ann. Intern. Med. 121, 241-246
30. Giovannucci, E., Egan, K. M., Hunter, D. J., Stampfer, M. J., Colditz, G. A., Willett, W. C., and Speizer, F. E. (1995) N. Engl. J. Med. 333, 609-614
31. Rosenberg, L., Palmer, J. R., Zauber, A. G., Warshauer, M. E., Stolley, P. D., and Shapiro, S. (1991) J. Natl. Cancer Inst. 83, 355-358
32. Duggan, D. E., Hooke, K. F., Risley, E. A., Shen, T. Y., and Van Arman, C. G. (1977) J. Pharmacol. Exp. Ther. 201, 8-13
33. Duggan, D. E., Hooke, K. F., and Hwang, S. S. (1980) Drug Metab. Dispos. 8, 241-246
34. Shen, T. Y., and Winter, C. A. (1977) Adv. Drug Res 12, 90-246
35. Meade, E. A., Smith, W. L., and DeWitt, D. L. (1993) J. Biol. Chem. 268, 6610-6614
36. Thompson, H. J., Jiang, C., Lu, J., Mehta, R. G., Piazza, G. A., Paranka, N. S., Pamukcu, R., and Ahnen, D. J. (1997) Cancer Res. 67, 267-271
37. Hanif, R., Pittas, A., Feng, Y., Koutsos, M. I., Qiao, L., Staiano-Coico, L., Shiff, S. I., and Riggs, B. (1996) Biochem. Pharmacol. 52, 237-245
38. Labayle, D., Fischer, D., Vielh, P., Drouhin, F., Pariente, A., Bories, C., Duhamel, O., Trousset, M., and Attali, P. (1991) Gastroenterology 101, 635-639
39. Rigau, J., Pique, J. M., Rukbio, E., Planas, R., Tarrech, J. M., and Bordas, J. M. (1991) Ann. Intern. Med. 115, 952-954
40. Giardiello, F. M., Hamilton, S. R., Krush, A. J., Piantadosi, S., Hylind, L. M., Celano, P., Booker, S. V., Robinson, C. R., and Offerhaus, G. J. (1993) N. Engl. J. Med. 328, 1313-1316
41. Rao, C. V., Rivenson, A., Simi, B., Zang, E., Kelloff, G., Steele, V., and Reddy, B. S. (1995) Cancer Res. 55, 1464-1472
42. Winde, G., Schmid, K. W., Schlegel, W., Fischer, R., Osswald, H., and Bunte, H. (1995) Dis. Colon Rectum 38, 813-830
43. Pasricha, P. J., Bedi, A., O'Connor, K., Rashid, A., Akhtar, A. J., Zahurak, M. L., Piantadosi, S., Hamilton, S. R., and Giardiello, F. M. (1995) Gastroenterology 109, 994-998
44. Shiff, S. J., Qiao, L., Tsai, L. L., and Rigas, B. (1995) J. Clin. Invest. 96, 491-503
45. Goldberg, Y., Nassif, H. I., Pittas, A., Tsai, L. L., Dynlacht, B. D., Rigas, B., and Shiff, S. J. (1996) Oncogene 12, 893-901
46. Mahmoud, N. N., Boolbol, S. K., Dannenberg, A. J., Mestre, J. R., Billinski, R. T., Martucci, C., Newmark, H. L., Chadburn, A., and Bertagnolli, M. M. (1998) Carcinogenesis 19, 87-91
47. Qiao, L., Shiff, S. J., and Rigas, B. (1998) Int. J. Cancer 76, 99-104
48. Ruschoff, J., Wallinger, S., Dietmaier, W., Bocker, T., Brockhoff, G., Hofstadter, F., and Fishel, R. (1998) Proc. Natl. Acad, Sci. U. S. A. 95, 11301-11306
49. Yin, M.-J., Christerson, L. B., Yamamoto, Y., Kwak, Y.-T., Xu, S., Mercurio, F., Barbosa, M., Cobb, M. H., and Gaynor, R. B. (1998) Cell 93, 875-884
50. Osborn, L., Kunkel, S., and Nabel, G. J. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 2336-2340
51. Malinin, N. L., Boldin, M. P., Kovalenko, A. V., and Wallach, D. (1997) Nature 385, 540-548
52. Chen, Z. J., Parent, L., and Maniatis, T. (1996) Cell 84, 853-862
53. Lee, F. S., Hagler, J., Chen, Z. J., and Maniatis, T. (1997) Cell 88, 213-222
54. Boulton, T. G., Nye, S. H., Robbins, D. J., Ip, N. Y., Radziejewska, E., Morgenbesser, S. D., DePinho, R. A., Panayotatos, N., Cobb, M. H., and Yancopoulos, G. D. (1991) Cell 65, 663-675
55. Kyriakis, J. M., Banerjee, P., Nikolakaki, E., Dai, T., Rubie, E. A., Ahmad, M. F., Avruch, J., and Woodgett, J, R. (1994) Nature 369, 156-160
56. Xu, S., and Cobb, M. H. (1997) J. Biol. Chem. 272, 32056-32060
57. Vane, J. R. (1971) Nat. New Biol. 231, 232-235
58. Mitchell, J. A., Akarasereenont, P., Thiemermann, C., Flower, R. J., and Vane, J. R. (1994) Proc. Natl. Acad. Sci. U. S. A. 80, 11693-11697
59. Vane, J. (1994) Nature 367, 215-216
60. Insel, P. (1996) in The Pharmacological Basis of Therapeutics (Hardman, J. G., Molinoff, P. B., Rudden, R. W., and Gilman, A. G., eds) pp. 617-657, McGraw-Hill Inc., New York