Circulating hTERT DNA in early breast cancer

Anticancer Research

Volumn 29, Issue 7, 2009, Pages 2845-2849

  Divella, Rosa ^a   Tommasi, Stefania ^a   Lacalamita, Rosanna ^a   Daniele, Antonella ^a   Abbate, Ines ^a   Garrisi, Vito Michele ^a   Savino, Eufemia ^a   Coviello, Maria ^a   Rubini, Vincenza ^a   Simone, Giovanni ^a   Paradiso, Angelo ^a   Quaranta, Michele ^a  

^a NATIONAL CANCER INSTITUTE GIOVANNI PAOLO II   (Italy)

Author keywords

Breast cancer; Circulating DNA; hTERT; Real time PCR; Tumor marker

Indexed keywords

CA 15-3 ANTIGEN; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; TELOMERASE REVERSE TRANSCRIPTASE;

ADULT; AGED; ARTICLE; BREAST CANCER; BREAST FIBROADENOMA; CLINICAL FEATURE; CONTROLLED STUDY; EARLY CANCER; FEMALE; HUMAN; MAJOR CLINICAL STUDY; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY;

BREAST NEOPLASMS; DNA; EARLY DIAGNOSIS; FEMALE; HUMANS; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TELOMERASE;

EID: 69249194732     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Jemal A, Thomas A, Murray T and Thurn M: Cancer statistics. Cancer J Clin 52: 23-47, 2002.
2. Fischer B, Bauer M and Wickerhb DL: Relation of number of positive axillary nodes to the prognosis of patients with primary breast cancer. An NJABP update. Cancer 52: 1551-1557, 1983.
3. Harris L, Fritsche H, Mennel R, Norton L, Ravdin P, Taube S, Somerfield MR, Hayes DF and Bast RC; American Society of Clinical Oncology 2007: Update of recommendations for the use of tumor markers in breast cancer. J Clin Oncolo 25(33): 5287-5312, 2007.
4. Pantel K, Muller V, Aver M, Nusser N, Harbeck N and Braun S: Detection and clinical implications of early systemic tumour cell dissemination in breast cancer. Clin Cancer Res 9(7): 6326-6334, 2003. (Pubitemid 38031816)
5. Umetani N, Giuliano AF and Hiramtsu SH: Prediction of breast cancer tumor progression by integrity of free circulating DNA in serum. J Clin Oncol 24: 4270-4276, 2006. (Pubitemid 46630784)
6. Goebel G, Zitt M and Muller HM: Circulating nucleic acids in plasma or serum (CNAPs) as prognostic and predictive markers in patients with solid neoplasias. Dis Markers 21: 105-120, 2005. (Pubitemid 41566728)
7. Coulet F, Blons H, Cabelguenne A, Lecomte T, Lacourreye O, Brasnu D, Beaune P, Zucman J and Laurent-Puig P: Detection of plasma tumor DNA in head and neck squamous cell carcinoma by microsatellite typing and p53 mutation analysis. Cancer Res 60: 707-711, 2000. (Pubitemid 30094571)
8. Thijssen MA, Swinkels DW, Ruers TJ and De Kok JB: Difference between free circulating plasma and serum DNA in patients with colorectal liver metastases. Anticancer Res 22: 421-425, 2002.
9. Divella R, Lacalamita R, Tommasi S, Coviello M, Daniele A, Garrisi VM, Abbate I, Simone G, Gadaleta C, Paradiso A and Quaranta M: PAI-1, t-PA and circulating hTERT DNA as related to virus infection in liver carcinogenesis. Anticancer Res 28(1): 223-228, 2008. (Pubitemid 351362905)
10. Shaw JW and Bacchetti S: A survey of telomerase activity in human cancer. Eur J Cancer 33: 787-791, 1997. (Pubitemid 27239490)
11. Holt SE and Shay JW: Role of telomerase in cellular proliferation and cancer. J Cell Physiol 180: 10-18, 1999.
12. Kirkpatrick K and Mombel K: The significance of human telomerase reverse transcriptase in human cancer. Eur J Surg Oncol 27: 754-760, 2001. (Pubitemid 33085546)
13. Rhyu MS: Telomeres, telomerase and immortality. J Natl Cancer Inst 87: 884-894, 1995.
14. Bisoffi M, Headhy CM and Grffith JW: Telomeres: prognostic markers for solid tumors. Int J Cancer 119: 2255-2260, 2006. (Pubitemid 44546943)
15. Shpitz B, Zimlichman S, Zemer R, Bomstein Y, Zehavi T, Liverant S, Bernehim J, Kaufman Z, Klein E, Shapira Y and Klein A: Telomerase activity in ductal carcinoma in situ of the breast. Breast Cancer Res Treat 58: 65-69, 1999. (Pubitemid 30003872)
16. Mokbel K: The role of telomerase in breast cancer. Eur J Surg Oncol 26(5): 509-514, 2000.
17. Hines WC, Fasardo AM, Joste NE, Bisoffi M and Griffith JK: Quantitative and spatial measurements of telomerase reverse transcriptase expression within normal and malignant human breast tissues. Mol Cancer Res 9: 503-509, 2005. (Pubitemid 41377640)
18. Quaranta M, Daniele A, Coviello M, Venneri MT, Abbate I, Caringella ME, Ditardo S, Divella R, Trerotoli P, DiGennaro M, Schittulli F, Fransvea E and Giannelli G: MMP-2, MMP-9, VEGF and CA 15.3 in breast cancer. Anticancer Res 27: 3593-3600, 2007. (Pubitemid 47610486)
19. Hosseini-Asl S, Atri M, Modarressi MH, Salhab M, Mokbel K and Mehidipour P: The expression of hTR and hTERT in human breast cancer: correlation with clinico-pathological parameters. Int Semin in Surg Oncol 3(2): 1-5, 2006. (Pubitemid 44446210)
20. Wu TL, Zhang D, Chia SH, Tsao KH, Sun CF and Wu JT: Cell-free DNA: measurement in various carcinomas and establishment of normal reference range. Clin Chim Acta 321: 77-87, 2002. (Pubitemid 34597056)
21. Zanetti-Dallenbach RA, Schmid S, Wight E, Holzgreve W, Ladewig A, Hahn S and Zhong XY: Levels of circulating cell-free serum DNA in benign and malignant breast lesions. Int J of Biol Markers 22(2): 95-99, 2007. (Pubitemid 47062213)
22. Narisawa-Saito M, Yoshimatsu Y, Ohno S, Yugawa T, Egawa N, Fujita M, Hirohashi S and Kiyono T: An in vitro multistep carcinogenesis model for human cervical cancer. Cancer Res 68(14): 5699-5705, 2008.
23. Altimari A, Grigioni AD, Benedettini E, Gabusi E, Schiavina R, Martinelli A, Morselli-Labate AM, Martonara G, Grigioni WF and Fiorentino M: Diagnostic role of circulating free plasma DNA detection in patients with localized prostate cancer. Am J Clin Pathol 129(5): 756-762, 2008.
24. Boddy IL, Gal S, Malone PR, Harris AL and Wainscoal JS: Prospective study of plasma DNA levels in the diagnosis of malignant versus benign prostate disease. Clin Cancer Res 11: 1394-1399, 2005. (Pubitemid 40315218)
25. Hiyama E and Hiyama K: Telomerase detection in the diagnosis and prognosis of cancer. Cytotechnology 45(1-2): 61-74, 2004. (Pubitemid 40568824)
26. Kassen M, Abdhallah BM, Yu Z, Ditzel N and Burns JJ: The use of hTERT-immortalized cells in tissue engineering. Cytotechnology 45(1-2): 39-46, 2004. (Pubitemid 40568822)
27. Kyo S, Takakura M, Kohama T and Inoue M: Telomerase activity in human endometrium. Cancer Res 57: 610-614, 1997.
28. Takakura M, Kyo S, Kanaya T, Tanaka M and Inoue M: Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer. Cancer Res 58: 1558-1561, 1998. (Pubitemid 28193624)
29. Hombach-Klonish S, Kehlen A, Fowler PA, Huppertz B, Jurget JF, Bischoff G, Schluter E, Buchmann J and Klonish T: Regulation of functional steroid receptors and ligand-induced responses in telomerase-immortalized human endometrial epithelial cells. J Mol Endocrinol 34(2): 517-534, 2005. (Pubitemid 40585199)
30. Duffy MJ: Serum tumor markers in breast cancer: are they of clinical value? Clin Chem 52(3): 345-351, 2006.
31. Duffy MJ, Duggan C, Keane R, Hill A, McDermott E, Crown J and O'Higgins N: High preoperative CA 15.3 concentrations predict adverse outcome in node-negative and node-positive breast cancer: study of 600 patients with histologically confirmed breast cancer. Clin Chem 50(3): 559-563, 2004. (Pubitemid 38297306)
32. Baldus SE, Engelmann K and Hanisch FG: MUC1 and the MUCs: a family of human mucins with impact in cancer biology. Crit Rev Clin Lab Sci 41: 189-231, 2004. (Pubitemid 38765096)
33. Reginbald LH, Pilarski LM, Longenecker BM, Reddish MA, Zimmermann G and Hugh JC: The breast mucin MUC1 as a novel adhesion ligand for endothelial intercellular adhesion molecule 1 in breast cancer. Cancer Res 56: 4244-4249, 1996. (Pubitemid 26305023)
34. Hattrup CL and Gendler SJ: MUC-1 alters oncogenic events and transcription in human breast cancer cells. Breast Cancer Res 8(4): 37, 2006.
35. Schroeder JA, Masri AA, Adriance MC, Tessier JC, Kotlarczyk KL, Thompson MC and Gendler SJ: MUC-1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation. Oncogene 23: 5739-5747, 2004.