-
1
-
-
0242667837
-
Stem cells and breast cancer: a field in transit
-
Smalley M, Ashworth A. Stem cells and breast cancer: a field in transit. Nat Rev Cancer 2003; 3: 832-844.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 832-844
-
-
Smalley, M.1
Ashworth, A.2
-
2
-
-
34548268026
-
Modelling breast cancer: one size does not fit all
-
Vargo-Gogola T, Rosen JM. Modelling breast cancer: one size does not fit all. Nat Rev Cancer 2007; 7: 659-672.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 659-672
-
-
Vargo-Gogola, T.1
Rosen, J.M.2
-
4
-
-
4444376712
-
Signaling to NF-κB
-
Hayden MS, Ghosh S. Signaling to NF-κB. Genes Dev 2004; 18: 2195-2224.
-
(2004)
Genes Dev.
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
5
-
-
33745298519
-
Nuclear factor-κB in cancer development and progression
-
Karin M. Nuclear factor-κB in cancer development and progression. Nature 2006; 441: 431-436.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
6
-
-
33846685017
-
NF-κB activation in development and progression of cancer
-
Inoue J, Gohda J, Akiyama T et al. NF-κB activation in development and progression of cancer. Cancer Sci 2007; 98: 268-274.
-
(2007)
Cancer Sci.
, vol.98
, pp. 268-274
-
-
Inoue, J.1
Gohda, J.2
Akiyama, T.3
-
7
-
-
0030927167
-
Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth
-
Nakshatri H, Bhat-Nakshatri P, Martin DA et al. Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth. Mol Cell Biol 1997; 17: 3629-3639.
-
(1997)
Mol Cell Biol.
, vol.17
, pp. 3629-3639
-
-
Nakshatri, H.1
Bhat-Nakshatri, P.2
Martin, D.A.3
-
8
-
-
3042716638
-
NF-κB activation in human breast cancer specimens and its role in cell proliferation and apoptosis
-
USA
-
Biswas DK, Shi Q, Baily S et al. NF-κB activation in human breast cancer specimens and its role in cell proliferation and apoptosis. Proc Natl Acad Sci USA 2004; 101: 10137-10142.
-
(2004)
Proc Natl Acad Sci.
, vol.101
, pp. 10137-10142
-
-
Biswas, D.K.1
Shi, Q.2
Baily, S.3
-
9
-
-
0033623848
-
IKKε is part of a novel PMA-inducible IκB kinase complex
-
Peters RT, Liao SM, Maniatis T. IKKε is part of a novel PMA-inducible IκB kinase complex. Mol Cell 2000; 5: 513-522.
-
(2000)
Mol Cell
, vol.5
, pp. 513-522
-
-
Peters, R.T.1
Liao, S.M.2
Maniatis, T.3
-
10
-
-
34249993765
-
Integrative genomic approaches identify IKBKE as a breast cancer oncogene
-
Boehm JS, Zhao JJ, Yao J et al. Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell 2007; 129: 1065-1079.
-
Cell 2007
, vol.129
, pp. 1065-1079
-
-
Boehm, J.S.1
Zhao, J.J.2
Yao, J.3
-
11
-
-
34547697174
-
Novel clusters of highly expressed genes accompany genomic amplification in breast cancers
-
Ito E, Honma R, Yanagisawa Y et al. Novel clusters of highly expressed genes accompany genomic amplification in breast cancers. FEBS Lett 2007; 581: 3909-3914.
-
(2007)
FEBS Lett.
, vol.581
, pp. 3909-3914
-
-
Ito, E.1
Honma, R.2
Yanagisawa, Y.3
-
12
-
-
85047695761
-
Ligand-independent signaling by overexpressed CD30 drives NF-κB activation in Hodgkin-Reed-Sternberg cells
-
Horie R, Watanabe T, Morishita Y et al. Ligand-independent signaling by overexpressed CD30 drives NF-κB activation in Hodgkin-Reed-Sternberg cells. Oncogene 2002; 21: 2493-2503.
-
(2002)
Oncogene
, vol.21
, pp. 2493-2503
-
-
Horie, R.1
Watanabe, T.2
Morishita, Y.3
-
13
-
-
40949092796
-
NOTCH3 signaling pathway plays crucial roles in proliferation of ErbB2-negative human breast cancer cells
-
Yamaguchi N, Oyama T, Ito E et al. NOTCH3 signaling pathway plays crucial roles in proliferation of ErbB2-negative human breast cancer cells. Cancer Res 2008; 68: 1881-1888.
-
(2008)
Cancer Res.
, vol.68
, pp. 1881-1888
-
-
Yamaguchi, N.1
Oyama, T.2
Ito, E.3
-
14
-
-
31044441241
-
Gene expression profiling of breast cell lines identifies potential new basal markers
-
Charafe-Jauffret E, Ginestier C, Monville F et al. Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene 2006;25: 2273-2284.
-
(2006)
Oncogene
, vol.25
, pp. 2273-2284
-
-
Charafe-Jauffret, E.1
Ginestier, C.2
Monville, F.3
-
15
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
Neve RM, Chin K, Fridlyand J et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006; 10:515-527.
-
(2006)
Cancer Cell
, vol.10
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
-
16
-
-
34547562418
-
Frequent engagement of the classical and alternative NF-κB pathways by diverse genetic abnormalities in multiple myeloma
-
Annunziata CM, Davis RE, Demchenko Y et al. Frequent engagement of the classical and alternative NF-κB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell 2007; 12: 115-130.
-
(2007)
Cancer Cell
, vol.12
, pp. 115-130
-
-
Annunziata, C.M.1
Davis, R.E.2
Demchenko, Y.3
-
17
-
-
34547660308
-
Promiscuous mutations activate the noncanonical NF-κB pathway in multiple myeloma
-
Keats JJ, Fonseca R, Chesi M et al. Promiscuous mutations activate the noncanonical NF-κB pathway in multiple myeloma. Cancer Cell 2007; 12:131-144.
-
(2007)
Cancer Cell
, vol.12
, pp. 131-144
-
-
Keats, J.J.1
Fonseca, R.2
Chesi, M.3
-
18
-
-
47249103531
-
The lymphotoxin-Β receptor is an upstream activator of NF-κB-mediated transcription in melanoma cells
-
Dhawan P, Su Y, Thu YM et al. The lymphotoxin-Β receptor is an upstream activator of NF-κB-mediated transcription in melanoma cells. J Biol Chem 2008; 283: 15399-408.
-
(2008)
J Biol Chem.
, vol.283
, pp. 15399-408
-
-
Dhawan, P.1
Su, Y.2
Thu, Y.M.3
-
19
-
-
46749111541
-
Overexpressed NF-κB-inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells
-
Saitoh Y, Yamamoto N, Dewan MZ et al. Overexpressed NF-κB-inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells. Blood 2008; 111: 5118-5129.
-
(2008)
Blood
, vol.111
, pp. 5118-5129
-
-
Saitoh, Y.1
Yamamoto, N.2
Dewan, M.Z.3
-
20
-
-
2942731516
-
Regulation of the NF-κB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation
-
Liao G, Zhang M, Harhaj EW et al. Regulation of the NF-κB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation. J Biol Chem 2004; 279: 26 243-250.
-
(2004)
J Biol Chem.
, vol.279
-
-
Liao, G.1
Zhang, M.2
Harhaj, E.W.3
-
21
-
-
0034730327
-
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development
-
Fata JE, Kong YY, Li J et al. The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development. Cell 2000; 103: 41-50.
-
(2000)
Cell
, vol.103
, pp. 41-50
-
-
Fata, J.E.1
Kong, Y.Y.2
Li, J.3
-
22
-
-
0034114950
-
Mammary glands of Aly mice:developmental changes and lactation-related expression of specific proteins, α-casein, GLyCAM-1 and MAdCAM-1
-
Nishimura T, Koike R, Miyasaka M. Mammary glands of Aly mice:developmental changes and lactation-related expression of specific proteins, α-casein, GLyCAM-1 and MAdCAM-1. Am J Reprod Immunol 2000; 43:351-358.
-
(2000)
Am J Reprod Immunol.
, vol.43
, pp. 351-358
-
-
Nishimura, T.1
Koike, R.2
Miyasaka, M.3
-
23
-
-
0035861314
-
IKKα provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development
-
Cao Y, Bonizzi G, Seagroves TN et al. IKKα provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development. Cell 2001; 107: 763-775.
-
(2001)
Cell
, vol.107
, pp. 763-775
-
-
Cao, Y.1
Bonizzi, G.2
Seagroves, T.N.3
-
24
-
-
40349100163
-
BRCA1 regulates human mammary stem/progenitor cell fate
-
USA
-
Liu S, Ginestier C, Charafe-Jauffret E et al. BRCA1 regulates human mammary stem/progenitor cell fate. Proc Natl Acad Sci USA 2008; 105: 1680-1685.
-
(2008)
Proc Natl Acad Sci.
, vol.105
, pp. 1680-1685
-
-
Liu, S.1
Ginestier, C.2
Charafe-Jauffret, E.3
-
25
-
-
21544480554
-
Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells
-
USA
-
Furuta S, Jiang X, Gu B et al. Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells. Proc Natl Acad Sci USA 2005; 102: 9176-9181.
-
(2005)
Proc Natl Acad Sci.
, vol.102
, pp. 9176-9181
-
-
Furuta, S.1
Jiang, X.2
Gu, B.3
-
26
-
-
34648821257
-
Molecular heterogeniety of breast carcinomas and the cancer stem hypothesis
-
Sting J, Caldas C. Molecular heterogeniety of breast carcinomas and the cancer stem hypothesis. Nat Rev Cancer 2007; 7: 791-799.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 791-799
-
-
Sting, J.1
Caldas, C.2
-
27
-
-
35648970074
-
IκB kinase α activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells
-
USA
-
Cao Y, Luo JL, Karin M. IκB kinase α activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells. Proc Natl Acad Sci USA 2007; 104: 15852-15857.
-
(2007)
Proc Natl Acad Sci.
, vol.104
, pp. 15852-15857
-
-
Cao, Y.1
Luo, J.L.2
Karin, M.3
-
28
-
-
65649107679
-
Nuclear factor-κB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo
-
Liu M, Ju X, Willmarth NE et al. Nuclear factor-κB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo. Am J Pathol 2009; 174: 1910-1920.
-
(2009)
Am J Pathol.
, vol.174
, pp. 1910-1920
-
-
Liu, M.1
Ju, X.2
Willmarth, N.E.3
-
29
-
-
44949240664
-
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
-
Bertrand MJ, Milutinovic S, Dickson KM et al. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell 2008; 30: 689-700.
-
(2008)
Mol Cell
, vol.30
, pp. 689-700
-
-
Bertrand, M.J.1
Milutinovic, S.2
Dickson, K.M.3
-
30
-
-
50149121101
-
Both cIAP1 and cIAP2 regulate TNFα-mediated NF-κB activation
-
USA
-
Mahoney DJ, Cheung HH, Mrad RL et al. Both cIAP1 and cIAP2 regulate TNFα-mediated NF-κB activation. Proc Natl Acad Sci USA 2008; 105: 11778-17783.
-
(2008)
Proc Natl Acad Sci.
, vol.105
, pp. 11778-17783
-
-
Mahoney, D.J.1
Cheung, H.H.2
Mrad, R.L.3
-
31
-
-
54049155149
-
c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFα)-induced NF-κB activation
-
Varfolomeev E, Goncharov T, Fedorova AV et al. c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFα)-induced NF-κB activation. J Biol Chem 2008; 283: 24295-24299.
-
(2008)
J Biol Chem.
, vol.283
, pp. 24295-24299
-
-
Varfolomeev, E.1
Goncharov, T.2
Fedorova, A.V.3
-
32
-
-
0041355495
-
A selective IKK-2 inhibitor blocks NF-κB-dependent gene expression in interleukin-1Β-stimulated synovial fibroblasts
-
Kishore N, Sommers C, Mathialagan S et al. A selective IKK-2 inhibitor blocks NF-κB-dependent gene expression in interleukin-1Β-stimulated synovial fibroblasts. J Biol Chem 2003; 278: 32861-32871.
-
(2003)
J Biol Chem.
, vol.278
, pp. 32861-32871
-
-
Kishore, N.1
Sommers, C.2
Mathialagan, S.3
-
33
-
-
63249092765
-
Persistently activated Stat3 maintains constitutive NF-κB activity in tumors
-
Lee H, Herrmann A, Deng JH et al. Persistently activated Stat3 maintains constitutive NF-κB activity in tumors. Cancer Cell 2009; 15: 283-293.
-
(2009)
Cancer Cell
, vol.15
, pp. 283-293
-
-
Lee, H.1
Herrmann, A.2
Deng, J.H.3
-
34
-
-
55749104730
-
The CD44+/CD24-phenotype is enriched in basal-like breast tumors
-
Honeth G, Bendahl PO, Ringner M et al. The CD44+/CD24-phenotype is enriched in basal-like breast tumors. Breast Cancer Res 2008; 10: R53.
-
(2008)
Breast Cancer Res.
, vol.10
-
-
Honeth, G.1
Bendahl, P.O.2
Ringner, M.3
-
35
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors.Nat Genet 2008; 40: 499-507.
-
(2008)
Nat Genet.
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
|