PTEN reverses MDM2-mediated chemotherapy resistance by interacting with p53 in acute lymphoblastic leukemia cells

Cancer Research

Volumn 63, Issue 19, 2003, Pages 6357-6362

  Zhou, Muxiang ^a   Gu, Lubing ^a   Findley, Harry W ^a   Jiang, Rong ^a   Woods, William G ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P53;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REPORTER GENE; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTIBIOTICS, ANTINEOPLASTIC; CELL DIVISION; CELL LINE, TUMOR; CHILD; DNA DAMAGE; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; HUMANS; LEUKEMIA, B-CELL, ACUTE; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; NUCLEAR PROTEINS; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MDM2; PTEN PHOSPHOHYDROLASE; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0141919562     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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