Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages

Biochemical and Biophysical Research Communications

Volumn 420, Issue 4, 2012, Pages 857-861

  Fernandes, Cláudia A ^a   Fievez, Laurence ^b   Neyrinck, Audrey M ^a   Delzenne, Nathalie M ^a   Bureau, Fabrice ^b   Vanbever, Rita ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Cambinol; Inflammation; Lipopolysaccharide; Macrophages; NAD dependent enzymes; Nuclear factor kappa B; Sirtinol; Sirtuins

Indexed keywords

CAMBINOL; CYTOKINE; HISTONE DEACETYLASE INHIBITOR; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; RANTES; SIRTINOL; SIRTUIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MACROPHAGE; MACROPHAGE ACTIVATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; CELL LINE; CHEMOKINE CCL5; CYTOKINES; HISTONE DEACETYLASE INHIBITORS; INFLAMMATION; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NAPHTHALENES; NF-KAPPA B; PHOSPHORYLATION; PYRIMIDINONES; SIRTUINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84859822652     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.03.088     Document Type: Article

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