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Volumn 7, Issue 3, 2012, Pages

Charting the NF-κB pathway interactome map

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

EID: 84857706271     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032678     Document Type: Article
Times cited : (67)

References (118)
  • 2
    • 16344376370 scopus 로고    scopus 로고
    • Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity
    • De Martinis M, Franceschi C, Monti D, Ginaldi L, (2005) Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity. FEBS Lett 579: 2035-2039.
    • (2005) FEBS Lett , vol.579 , pp. 2035-2039
    • De Martinis, M.1    Franceschi, C.2    Monti, D.3    Ginaldi, L.4
  • 4
    • 33646550890 scopus 로고    scopus 로고
    • Age-dependent modifications of Type 1 and Type 2 cytokines within virgin and memory CD4+ T cells in humans
    • Alberti S, Cevenini E, Ostan R, Capri M, Salvioli S, et al. (2006) Age-dependent modifications of Type 1 and Type 2 cytokines within virgin and memory CD4+ T cells in humans. Mech Ageing Dev 127: 560-566.
    • (2006) Mech Ageing Dev , vol.127 , pp. 560-566
    • Alberti, S.1    Cevenini, E.2    Ostan, R.3    Capri, M.4    Salvioli, S.5
  • 5
    • 33745451585 scopus 로고    scopus 로고
    • The immune risk phenotype is associated with IL-6 in the terminal decline stage: findings from the Swedish NONA immune longitudinal study of very late life functioning
    • Wikby A, Nilsson BO, Forsey R, Thompson J, Strindhall J, et al. (2006) The immune risk phenotype is associated with IL-6 in the terminal decline stage: findings from the Swedish NONA immune longitudinal study of very late life functioning. Mech Ageing Dev 127: 695-704.
    • (2006) Mech Ageing Dev , vol.127 , pp. 695-704
    • Wikby, A.1    Nilsson, B.O.2    Forsey, R.3    Thompson, J.4    Strindhall, J.5
  • 6
    • 35748936769 scopus 로고    scopus 로고
    • Massive load of functional effector CD4+ and CD8+ T cells against cytomegalovirus in very old subjects
    • Vescovini R, Biasini C, Fagnoni FF, Telera AR, Zanlari L, et al. (2007) Massive load of functional effector CD4+ and CD8+ T cells against cytomegalovirus in very old subjects. J Immunol 179: 4283-4291.
    • (2007) J Immunol , vol.179 , pp. 4283-4291
    • Vescovini, R.1    Biasini, C.2    Fagnoni, F.F.3    Telera, A.R.4    Zanlari, L.5
  • 9
    • 33846111415 scopus 로고    scopus 로고
    • Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans
    • Franceschi C, Capri M, Monti D, Giunta S, Olivieri F, et al. (2007) Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans. Mech Ageing Dev 128: 92-105.
    • (2007) Mech Ageing Dev , vol.128 , pp. 92-105
    • Franceschi, C.1    Capri, M.2    Monti, D.3    Giunta, S.4    Olivieri, F.5
  • 10
    • 77950254226 scopus 로고    scopus 로고
    • Systems Biology and Longevity: An Emerging Approach to Identify Innovative Anti-Aging Targets and Strategies
    • Cevenini E, Bellavista E, Tieri P, Castellani G, Lescai F, et al. (2010) Systems Biology and Longevity: An Emerging Approach to Identify Innovative Anti-Aging Targets and Strategies. Current Pharmaceutical Design pp. 802-813.
    • (2010) Current Pharmaceutical Design , pp. 802-813
    • Cevenini, E.1    Bellavista, E.2    Tieri, P.3    Castellani, G.4    Lescai, F.5
  • 11
    • 77951889646 scopus 로고    scopus 로고
    • Intense antiextracellular adaptive immune response to human cytomegalovirus in very old subjects with impaired health and cognitive and functional status
    • Vescovini R, Biasini C, Telera AR, Basaglia M, Stella A, et al. (2010) Intense antiextracellular adaptive immune response to human cytomegalovirus in very old subjects with impaired health and cognitive and functional status. J Immunol 184: 3242-3249.
    • (2010) J Immunol , vol.184 , pp. 3242-3249
    • Vescovini, R.1    Biasini, C.2    Telera, A.R.3    Basaglia, M.4    Stella, A.5
  • 12
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl H, (1999) Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18: 6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.1
  • 13
    • 84857745128 scopus 로고    scopus 로고
    • Rel/NF-kappaB Transcription Factors
    • Gilmore T, (2010) Rel/NF-kappaB Transcription Factors. Boston.
    • (2010) Boston
    • Gilmore, T.1
  • 14
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-kappaB and IKK function
    • Perkins N, (2007) Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 8: 49-62.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 49-62
    • Perkins, N.1
  • 15
    • 0024475227 scopus 로고
    • NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control
    • Lenardo M, Baltimore D, (1989) NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 58: 227-229.
    • (1989) Cell , vol.58 , pp. 227-229
    • Lenardo, M.1    Baltimore, D.2
  • 16
    • 33645312379 scopus 로고    scopus 로고
    • Circuitry of nuclear factor kappaB signaling
    • Hoffmann A, Baltimore D, (2006) Circuitry of nuclear factor kappaB signaling. Immunol Rev 210: 171-186.
    • (2006) Immunol Rev , vol.210 , pp. 171-186
    • Hoffmann, A.1    Baltimore, D.2
  • 17
    • 5644235488 scopus 로고    scopus 로고
    • NF-kappaB: a multifaceted transcription factor regulated at several levels
    • Schmitz M, Mattioli I, Buss H, Kracht M, (2004) NF-kappaB: a multifaceted transcription factor regulated at several levels. Chembiochem 5: 1348-1358.
    • (2004) Chembiochem , vol.5 , pp. 1348-1358
    • Schmitz, M.1    Mattioli, I.2    Buss, H.3    Kracht, M.4
  • 18
    • 65549164068 scopus 로고    scopus 로고
    • Roles of NF-kappaB in health and disease: mechanisms and therapeutic potential
    • Wong E, Tergaonkar V, (2009) Roles of NF-kappaB in health and disease: mechanisms and therapeutic potential. Clin Sci (Lond) 116: 451-465.
    • (2009) Clin Sci (Lond) , vol.116 , pp. 451-465
    • Wong, E.1    Tergaonkar, V.2
  • 19
    • 80052014052 scopus 로고    scopus 로고
    • Inflammation meets cancer, with NF-κB as the matchmaker
    • Ben-Neriah Y, Karin M, (2011) Inflammation meets cancer, with NF-κB as the matchmaker. Nat Immunol 12: 715-723.
    • (2011) Nat Immunol , vol.12 , pp. 715-723
    • Ben-Neriah, Y.1    Karin, M.2
  • 20
    • 80051977323 scopus 로고    scopus 로고
    • Celebrating 25 years of NF-κB
    • Editorial, (2011) Celebrating 25 years of NF-κB. Nat Immunol 12: 681.
    • (2011) Nat Immunol , vol.12 , pp. 681
    • Editorial1
  • 21
    • 80051959463 scopus 로고    scopus 로고
    • NF-κB is 25
    • Baltimore D, (2011) NF-κB is 25. Nat Immunol 12: 683-685.
    • (2011) Nat Immunol , vol.12 , pp. 683-685
    • Baltimore, D.1
  • 22
    • 62849094483 scopus 로고    scopus 로고
    • Navigating the network: signaling cross-talk in hematopoietic cells
    • Fraser I, Germain R, (2009) Navigating the network: signaling cross-talk in hematopoietic cells. Nat Immunol 10: 327-331.
    • (2009) Nat Immunol , vol.10 , pp. 327-331
    • Fraser, I.1    Germain, R.2
  • 23
    • 33846326304 scopus 로고    scopus 로고
    • Genetic screening for signal transduction in the era of network biology
    • Friedman A, Perrimon N, (2007) Genetic screening for signal transduction in the era of network biology. Cell 128: 225-231.
    • (2007) Cell , vol.128 , pp. 225-231
    • Friedman, A.1    Perrimon, N.2
  • 24
    • 45549089565 scopus 로고    scopus 로고
    • The art and design of genetic screens: RNA interference
    • Boutros M, Ahringer J, (2008) The art and design of genetic screens: RNA interference. Nat Rev Genet 9: 554-566.
    • (2008) Nat Rev Genet , vol.9 , pp. 554-566
    • Boutros, M.1    Ahringer, J.2
  • 27
    • 77956300684 scopus 로고    scopus 로고
    • A comprehensive molecular interaction map for rheumatoid arthritis
    • Wu G, Zhu L, Dent JE, Nardini C, (2010) A comprehensive molecular interaction map for rheumatoid arthritis. PLoS One 5: e10137.
    • (2010) PLoS One , vol.5
    • Wu, G.1    Zhu, L.2    Dent, J.E.3    Nardini, C.4
  • 28
    • 0033555859 scopus 로고    scopus 로고
    • Emergent properties of networks of biological signaling pathways
    • Bhalla U, Iyengar R, (1999) Emergent properties of networks of biological signaling pathways. Science 283: 381-387.
    • (1999) Science , vol.283 , pp. 381-387
    • Bhalla, U.1    Iyengar, R.2
  • 29
    • 0037212568 scopus 로고    scopus 로고
    • Understanding complex signaling networks through models and metaphors
    • Bhalla U, (2003) Understanding complex signaling networks through models and metaphors. Prog Biophys Mol Biol 81: 45-65.
    • (2003) Prog Biophys Mol Biol , vol.81 , pp. 45-65
    • Bhalla, U.1
  • 30
    • 34547490659 scopus 로고    scopus 로고
    • Non-linear dimensionality reduction of signaling networks
    • Ivakhno S, Armstrong J, (2007) Non-linear dimensionality reduction of signaling networks. BMC Syst Biol 1: 27.
    • (2007) BMC Syst Biol , vol.1 , pp. 27
    • Ivakhno, S.1    Armstrong, J.2
  • 31
  • 32
    • 80051988785 scopus 로고    scopus 로고
    • Hierarchies of NF-κB target-gene regulation
    • Smale ST, (2011) Hierarchies of NF-κB target-gene regulation. Nat Immunol 12: 689-694.
    • (2011) Nat Immunol , vol.12 , pp. 689-694
    • Smale, S.T.1
  • 33
    • 70349581497 scopus 로고    scopus 로고
    • Cytoscape: a community-based framework for network modeling
    • Killcoyne S, Carter G, Smith J, Boyle J, (2009) Cytoscape: a community-based framework for network modeling. Methods Mol Biol 563: 219-239.
    • (2009) Methods Mol Biol , vol.563 , pp. 219-239
    • Killcoyne, S.1    Carter, G.2    Smith, J.3    Boyle, J.4
  • 34
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: a software environment for integrated models of biomolecular interaction networks
    • Shannon P, Markiel A, Ozier O, Baliga N, Wang J, et al. (2003) Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 13: 2498-2504.
    • (2003) Genome Res , vol.13 , pp. 2498-2504
    • Shannon, P.1    Markiel, A.2    Ozier, O.3    Baliga, N.4    Wang, J.5
  • 36
    • 79958268165 scopus 로고    scopus 로고
    • Integrating omics data for signaling pathways, interactome reconstruction, and functional analysis
    • Tieri P, de la Fuente A, Termanini A, Franceschi C, (2011) Integrating omics data for signaling pathways, interactome reconstruction, and functional analysis. Methods Mol Biol 719: 415-433.
    • (2011) Methods Mol Biol , vol.719 , pp. 415-433
    • Tieri, P.1    de la Fuente, A.2    Termanini, A.3    Franceschi, C.4
  • 37
    • 33747853260 scopus 로고    scopus 로고
    • APID: Agile Protein Interaction DataAnalyzer
    • Prieto C, De Las Rivas J, (2006) APID: Agile Protein Interaction DataAnalyzer. Nucleic Acids Res 34: W298-302.
    • (2006) Nucleic Acids Res , vol.34
    • Prieto, C.1    de Las Rivas, J.2
  • 39
    • 1542399989 scopus 로고    scopus 로고
    • FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes
    • Al-Shahrour F, Díaz-Uriarte R, Dopazo J, (2004) FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes. Bioinformatics 20: 578-580.
    • (2004) Bioinformatics , vol.20 , pp. 578-580
    • Al-Shahrour, F.1    Díaz-Uriarte, R.2    Dopazo, J.3
  • 40
    • 21444445084 scopus 로고    scopus 로고
    • BABELOMICS: a suite of web tools for functional annotation and analysis of groups of genes in high-throughput experiments
    • Al-Shahrour F, Minguez P, Vaquerizas JM, Conde L, Dopazo J, (2005) BABELOMICS: a suite of web tools for functional annotation and analysis of groups of genes in high-throughput experiments. Nucleic Acids Res 33: W460-464.
    • (2005) Nucleic Acids Res , vol.33
    • Al-Shahrour, F.1    Minguez, P.2    Vaquerizas, J.M.3    Conde, L.4    Dopazo, J.5
  • 41
    • 77954339096 scopus 로고    scopus 로고
    • Babelomics: an integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional profiling
    • Medina I, Carbonell J, Pulido L, Madeira SC, Goetz S, et al. (2010) Babelomics: an integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional profiling. Nucleic Acids Res 38: W210-213.
    • (2010) Nucleic Acids Res , vol.38
    • Medina, I.1    Carbonell, J.2    Pulido, L.3    Madeira, S.C.4    Goetz, S.5
  • 42
    • 78149236787 scopus 로고    scopus 로고
    • DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks
    • Bauer-Mehren A, Rautschka M, Sanz F, Furlong LI, (2010) DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks. Bioinformatics 26: 2924-2926.
    • (2010) Bioinformatics , vol.26 , pp. 2924-2926
    • Bauer-Mehren, A.1    Rautschka, M.2    Sanz, F.3    Furlong, L.I.4
  • 43
    • 0035755351 scopus 로고    scopus 로고
    • Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base
    • Klein TE, Chang JT, Cho MK, Easton KL, Fergerson R, et al. (2001) Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base. Pharmacogenomics J 1: 167-170.
    • (2001) Pharmacogenomics J , vol.1 , pp. 167-170
    • Klein, T.E.1    Chang, J.T.2    Cho, M.K.3    Easton, K.L.4    Fergerson, R.5
  • 45
    • 2942552459 scopus 로고    scopus 로고
    • An automated method for finding molecular complexes in large protein interaction networks
    • Bader GD, Hogue CW, (2003) An automated method for finding molecular complexes in large protein interaction networks. BMC Bioinformatics 4: 2.
    • (2003) BMC Bioinformatics , vol.4 , pp. 2
    • Bader, G.D.1    Hogue, C.W.2
  • 46
    • 27744469130 scopus 로고    scopus 로고
    • High-betweenness proteins in the yeast protein interaction network
    • Joy MP, Brock A, Ingber DE, Huang S, (2005) High-betweenness proteins in the yeast protein interaction network. J Biomed Biotechnol pp. 96-103.
    • (2005) J Biomed Biotechnol , pp. 96-103
    • Joy, M.P.1    Brock, A.2    Ingber, D.E.3    Huang, S.4
  • 47
    • 34547101963 scopus 로고    scopus 로고
    • Characterization of protein-interaction networks in tumors
    • Platzer A, Perco P, Lukas A, Mayer B, (2007) Characterization of protein-interaction networks in tumors. BMC Bioinformatics 8: 224.
    • (2007) BMC Bioinformatics , vol.8 , pp. 224
    • Platzer, A.1    Perco, P.2    Lukas, A.3    Mayer, B.4
  • 48
    • 0033596127 scopus 로고    scopus 로고
    • Control of apoptosis by Rel/NF-kappaB transcription factors
    • Barkett M, Gilmore T, (1999) Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene 18: 6910-6924.
    • (1999) Oncogene , vol.18 , pp. 6910-6924
    • Barkett, M.1    Gilmore, T.2
  • 49
    • 0029851622 scopus 로고    scopus 로고
    • I(kappa)B(gamma) inhibits DNA binding of NF-kappaB p50 homodimers by interacting with residues that contact DNA
    • Bell S, Matthews J, Jaffray E, Hay R, (1996) I(kappa)B(gamma) inhibits DNA binding of NF-kappaB p50 homodimers by interacting with residues that contact DNA. Mol Cell Biol 16: 6477-6485.
    • (1996) Mol Cell Biol , vol.16 , pp. 6477-6485
    • Bell, S.1    Matthews, J.2    Jaffray, E.3    Hay, R.4
  • 50
    • 0036144763 scopus 로고    scopus 로고
    • Regulatory functions of ubiquitination in the immune system
    • Ben-Neriah Y, (2002) Regulatory functions of ubiquitination in the immune system. Nat Immunol 3: 20-26.
    • (2002) Nat Immunol , vol.3 , pp. 20-26
    • Ben-Neriah, Y.1
  • 51
    • 33646555078 scopus 로고    scopus 로고
    • Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors
    • Campbell K, O'Shea J, Perkins N, (2006) Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors. BMC Cancer 6: 101.
    • (2006) BMC Cancer , vol.6 , pp. 101
    • Campbell, K.1    O'Shea, J.2    Perkins, N.3
  • 52
    • 2342522110 scopus 로고    scopus 로고
    • Shaping the nuclear action of NF-kappaB
    • Chen L, Greene W, (2004) Shaping the nuclear action of NF-kappaB. Nat Rev Mol Cell Biol 5: 392-401.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 392-401
    • Chen, L.1    Greene, W.2
  • 53
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-kappaB pathway
    • Chen Z, (2005) Ubiquitin signalling in the NF-kappaB pathway. Nat Cell Biol 7: 758-765.
    • (2005) Nat Cell Biol , vol.7 , pp. 758-765
    • Chen, Z.1
  • 54
    • 0347624589 scopus 로고    scopus 로고
    • Dual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processing
    • Cohen S, Achbert-Weiner H, Ciechanover A, (2004) Dual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processing. Mol Cell Biol 24: 475-486.
    • (2004) Mol Cell Biol , vol.24 , pp. 475-486
    • Cohen, S.1    Achbert-Weiner, H.2    Ciechanover, A.3
  • 55
    • 0028170255 scopus 로고
    • Differential interactions of Rel-NF-kappa B complexes with I kappa B alpha determine pools of constitutive and inducible NF-kappa B activity
    • Dobrzanski P, Ryseck R, Bravo R, (1994) Differential interactions of Rel-NF-kappa B complexes with I kappa B alpha determine pools of constitutive and inducible NF-kappa B activity. EMBO J 13: 4608-4616.
    • (1994) EMBO J , vol.13 , pp. 4608-4616
    • Dobrzanski, P.1    Ryseck, R.2    Bravo, R.3
  • 56
    • 1442264796 scopus 로고    scopus 로고
    • The protein kinase PKR: a molecular clock that sequentially activates survival and death programs
    • Donzé O, Deng J, Curran J, Sladek R, Picard D, et al. (2004) The protein kinase PKR: a molecular clock that sequentially activates survival and death programs. EMBO J 23: 564-571.
    • (2004) EMBO J , vol.23 , pp. 564-571
    • Donzé, O.1    Deng, J.2    Curran, J.3    Sladek, R.4    Picard, D.5
  • 57
    • 0037569481 scopus 로고    scopus 로고
    • Proteasome inhibition: a new anti-inflammatory strategy
    • Elliott P, Zollner T, Boehncke W, (2003) Proteasome inhibition: a new anti-inflammatory strategy. J Mol Med 81: 235-245.
    • (2003) J Mol Med , vol.81 , pp. 235-245
    • Elliott, P.1    Zollner, T.2    Boehncke, W.3
  • 58
    • 0026758170 scopus 로고
    • The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa B-mediated inhibition
    • Franzoso G, Bours V, Park S, Tomita-Yamaguchi M, Kelly K, et al. (1992) The candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa B-mediated inhibition. Nature 359: 339-342.
    • (1992) Nature , vol.359 , pp. 339-342
    • Franzoso, G.1    Bours, V.2    Park, S.3    Tomita-Yamaguchi, M.4    Kelly, K.5
  • 59
    • 0037043125 scopus 로고    scopus 로고
    • Rel/NF-kappa B/I kappa B signal transduction in the generation and treatment of human cancer
    • Gilmore T, Gapuzan M, Kalaitzidis D, Starczynowski D, (2002) Rel/NF-kappa B/I kappa B signal transduction in the generation and treatment of human cancer. Cancer Lett 181: 1-9.
    • (2002) Cancer Lett , vol.181 , pp. 1-9
    • Gilmore, T.1    Gapuzan, M.2    Kalaitzidis, D.3    Starczynowski, D.4
  • 60
    • 39049183044 scopus 로고    scopus 로고
    • Regulation and function of IKK and IKK-related kinases
    • Häcker H, Karin M, (2006) Regulation and function of IKK and IKK-related kinases. Sci STKE 2006: re13.
    • (2006) Sci STKE , vol.2006
    • Häcker, H.1    Karin, M.2
  • 61
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappaB
    • Hayden M, Ghosh S, (2004) Signaling to NF-kappaB. Genes Dev 18: 2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.1    Ghosh, S.2
  • 62
    • 33845450836 scopus 로고    scopus 로고
    • SnapShot: NF-kappaB signaling pathways
    • Hayden M, West A, Ghosh S, (2006) SnapShot: NF-kappaB signaling pathways. Cell 127: 1286-1287.
    • (2006) Cell , vol.127 , pp. 1286-1287
    • Hayden, M.1    West, A.2    Ghosh, S.3
  • 63
    • 0035324928 scopus 로고    scopus 로고
    • Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells
    • Hinz M, Löser P, Mathas S, Krappmann D, Dörken B, et al. (2001) Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells. Blood 97: 2798-2807.
    • (2001) Blood , vol.97 , pp. 2798-2807
    • Hinz, M.1    Löser, P.2    Mathas, S.3    Krappmann, D.4    Dörken, B.5
  • 64
    • 33847180836 scopus 로고    scopus 로고
    • TGF-beta induces p65 acetylation to enhance bacteria-induced NF-kappaB activation
    • Ishinaga H, Jono H, Lim J, Kweon S, Xu H, et al. (2007) TGF-beta induces p65 acetylation to enhance bacteria-induced NF-kappaB activation. EMBO J 26: 1150-1162.
    • (2007) EMBO J , vol.26 , pp. 1150-1162
    • Ishinaga, H.1    Jono, H.2    Lim, J.3    Kweon, S.4    Xu, H.5
  • 65
    • 3042834382 scopus 로고    scopus 로고
    • The IkappaB kinase complex and NF-kappaB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1
    • Krappmann D, Wegener E, Sunami Y, Esen M, Thiel A, et al. (2004) The IkappaB kinase complex and NF-kappaB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1. Mol Cell Biol 24: 6488-6500.
    • (2004) Mol Cell Biol , vol.24 , pp. 6488-6500
    • Krappmann, D.1    Wegener, E.2    Sunami, Y.3    Esen, M.4    Thiel, A.5
  • 66
    • 0035976962 scopus 로고    scopus 로고
    • IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells
    • Malek S, Chen Y, Huxford T, Ghosh G, (2001) IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells. J Biol Chem 276: 45225-45235.
    • (2001) J Biol Chem , vol.276 , pp. 45225-45235
    • Malek, S.1    Chen, Y.2    Huxford, T.3    Ghosh, G.4
  • 67
    • 0037482136 scopus 로고    scopus 로고
    • X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex
    • Malek S, Huang D, Huxford T, Ghosh S, Ghosh G, (2003) X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex. J Biol Chem 278: 23094-23100.
    • (2003) J Biol Chem , vol.278 , pp. 23094-23100
    • Malek, S.1    Huang, D.2    Huxford, T.3    Ghosh, S.4    Ghosh, G.5
  • 68
    • 33646548968 scopus 로고    scopus 로고
    • The 20S proteasome processes NF-kappaB1 p105 into p50 in a translation-independent manner
    • Moorthy A, Savinova O, Ho J, Wang V, Vu D, et al. (2006) The 20S proteasome processes NF-kappaB1 p105 into p50 in a translation-independent manner. EMBO J 25: 1945-1956.
    • (2006) EMBO J , vol.25 , pp. 1945-1956
    • Moorthy, A.1    Savinova, O.2    Ho, J.3    Wang, V.4    Vu, D.5
  • 69
    • 33646001448 scopus 로고    scopus 로고
    • Dissection of the NF-kappaB signalling cascade in transgenic and knockout mice
    • Pasparakis M, Luedde T, Schmidt-Supprian M, (2006) Dissection of the NF-kappaB signalling cascade in transgenic and knockout mice. Cell Death Differ 13: 861-872.
    • (2006) Cell Death Differ , vol.13 , pp. 861-872
    • Pasparakis, M.1    Luedde, T.2    Schmidt-Supprian, M.3
  • 70
    • 28444491798 scopus 로고    scopus 로고
    • Constitutive NF-kappaB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival
    • Pham L, Tamayo A, Yoshimura L, Lin-Lee Y, Ford R, (2005) Constitutive NF-kappaB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival. Blood 106: 3940-3947.
    • (2005) Blood , vol.106 , pp. 3940-3947
    • Pham, L.1    Tamayo, A.2    Yoshimura, L.3    Lin-Lee, Y.4    Ford, R.5
  • 71
    • 0033605424 scopus 로고    scopus 로고
    • Nuclear retention of IkappaBalpha protects it from signal-induced degradation and inhibits nuclear factor kappaB transcriptional activation
    • Rodriguez M, Thompson J, Hay R, Dargemont C, (1999) Nuclear retention of IkappaBalpha protects it from signal-induced degradation and inhibits nuclear factor kappaB transcriptional activation. J Biol Chem 274: 9108-9115.
    • (1999) J Biol Chem , vol.274 , pp. 9108-9115
    • Rodriguez, M.1    Thompson, J.2    Hay, R.3    Dargemont, C.4
  • 72
    • 0038771214 scopus 로고    scopus 로고
    • Modulation of NF-kappaB activity by exchange of dimers
    • Saccani S, Pantano S, Natoli G, (2003) Modulation of NF-kappaB activity by exchange of dimers. Mol Cell 11: 1563-1574.
    • (2003) Mol Cell , vol.11 , pp. 1563-1574
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 73
    • 40949123149 scopus 로고    scopus 로고
    • Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
    • Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarniranta K, et al. (2008) Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Res Rev 7: 83-105.
    • (2008) Ageing Res Rev , vol.7 , pp. 83-105
    • Salminen, A.1    Huuskonen, J.2    Ojala, J.3    Kauppinen, A.4    Kaarniranta, K.5
  • 74
    • 0025943986 scopus 로고
    • The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B
    • Schmitz M, Baeuerle P, (1991) The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B. EMBO J 10: 3805-3817.
    • (1991) EMBO J , vol.10 , pp. 3805-3817
    • Schmitz, M.1    Baeuerle, P.2
  • 75
    • 41949103636 scopus 로고    scopus 로고
    • SnapShot: The TGFbeta pathway interactome
    • Taylor I, Wrana J, (2008) SnapShot: The TGFbeta pathway interactome. Cell 133: 378.e371.
    • (2008) Cell , vol.133
    • Taylor, I.1    Wrana, J.2
  • 76
    • 0028986194 scopus 로고
    • I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B
    • Thompson J, Phillips R, Erdjument-Bromage H, Tempst P, Ghosh S, (1995) I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B. Cell 80: 573-582.
    • (1995) Cell , vol.80 , pp. 573-582
    • Thompson, J.1    Phillips, R.2    Erdjument-Bromage, H.3    Tempst, P.4    Ghosh, S.5
  • 77
    • 1442278555 scopus 로고    scopus 로고
    • Expression of activated M-Ras in a murine mammary epithelial cell line induces epithelial-mesenchymal transition and tumorigenesis
    • Ward K, Zhang K, Somasiri A, Roskelley C, Schrader J, (2004) Expression of activated M-Ras in a murine mammary epithelial cell line induces epithelial-mesenchymal transition and tumorigenesis. Oncogene 23: 1187-1196.
    • (2004) Oncogene , vol.23 , pp. 1187-1196
    • Ward, K.1    Zhang, K.2    Somasiri, A.3    Roskelley, C.4    Schrader, J.5
  • 78
    • 33745494351 scopus 로고    scopus 로고
    • Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation
    • Wegener E, Oeckinghaus A, Papadopoulou N, Lavitas L, Schmidt-Supprian M, et al. (2006) Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation. Mol Cell 23: 13-23.
    • (2006) Mol Cell , vol.23 , pp. 13-23
    • Wegener, E.1    Oeckinghaus, A.2    Papadopoulou, N.3    Lavitas, L.4    Schmidt-Supprian, M.5
  • 79
    • 33645975534 scopus 로고    scopus 로고
    • Deciphering the pathway from the TCR to NF-kappaB
    • Weil R, Israël A, (2006) Deciphering the pathway from the TCR to NF-kappaB. Cell Death Differ 13: 826-833.
    • (2006) Cell Death Differ , vol.13 , pp. 826-833
    • Weil, R.1    Israël, A.2
  • 80
    • 3943054838 scopus 로고    scopus 로고
    • De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
    • Wertz I, O'Rourke K, Zhou H, Eby M, Aravind L, et al. (2004) De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature 430: 694-699.
    • (2004) Nature , vol.430 , pp. 694-699
    • Wertz, I.1    O'Rourke, K.2    Zhou, H.3    Eby, M.4    Aravind, L.5
  • 81
    • 0030899121 scopus 로고    scopus 로고
    • I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity
    • Whiteside S, Epinat J, Rice N, Israël A, (1997) I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity. EMBO J 16: 1413-1426.
    • (1997) EMBO J , vol.16 , pp. 1413-1426
    • Whiteside, S.1    Epinat, J.2    Rice, N.3    Israël, A.4
  • 82
    • 0026783677 scopus 로고
    • Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B
    • Wulczyn F, Naumann M, Scheidereit C, (1992) Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B. Nature 358: 597-599.
    • (1992) Nature , vol.358 , pp. 597-599
    • Wulczyn, F.1    Naumann, M.2    Scheidereit, C.3
  • 83
    • 13444305306 scopus 로고    scopus 로고
    • TRED: a Transcriptional Regulatory Element Database and a platform for in silico gene regulation studies
    • Zhao F, Xuan Z, Liu L, Zhang M, (2005) TRED: a Transcriptional Regulatory Element Database and a platform for in silico gene regulation studies. Nucleic Acids Res 33: D103-107.
    • (2005) Nucleic Acids Res , vol.33
    • Zhao, F.1    Xuan, Z.2    Liu, L.3    Zhang, M.4
  • 84
    • 33846107777 scopus 로고    scopus 로고
    • TRED: a transcriptional regulatory element database, new entries and other development
    • Jiang C, Xuan Z, Zhao F, Zhang M, (2007) TRED: a transcriptional regulatory element database, new entries and other development. Nucleic Acids Res 35: D137-140.
    • (2007) Nucleic Acids Res , vol.35
    • Jiang, C.1    Xuan, Z.2    Zhao, F.3    Zhang, M.4
  • 86
    • 0033623848 scopus 로고    scopus 로고
    • IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex
    • Peters RT, Liao SM, Maniatis T, (2000) IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex. Mol Cell 5: 513-522.
    • (2000) Mol Cell , vol.5 , pp. 513-522
    • Peters, R.T.1    Liao, S.M.2    Maniatis, T.3
  • 87
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1
    • Malinin NL, Boldin MP, Kovalenko AV, Wallach D, (1997) MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1. Nature 385: 540-544.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 88
    • 77951218912 scopus 로고    scopus 로고
    • TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptor
    • Bista P, Zeng W, Ryan S, Bailly V, Browning JL, et al. (2010) TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptor. J Biol Chem 285: 12971-12978.
    • (2010) J Biol Chem , vol.285 , pp. 12971-12978
    • Bista, P.1    Zeng, W.2    Ryan, S.3    Bailly, V.4    Browning, J.L.5
  • 89
    • 0033570917 scopus 로고    scopus 로고
    • Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB
    • Nourbakhsh M, Hauser H, (1999) Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB. EMBO J 18: 6415-6425.
    • (1999) EMBO J , vol.18 , pp. 6415-6425
    • Nourbakhsh, M.1    Hauser, H.2
  • 90
    • 0242720415 scopus 로고    scopus 로고
    • TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology
    • Wu H, Arron JR, (2003) TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology. Bioessays 25: 1096-1105.
    • (2003) Bioessays , vol.25 , pp. 1096-1105
    • Wu, H.1    Arron, J.R.2
  • 91
    • 80051814602 scopus 로고    scopus 로고
    • Targeting of Toll-like receptors: a decade of progress in combating infectious diseases
    • Hedayat M, Netea MG, Rezaei N, (2011) Targeting of Toll-like receptors: a decade of progress in combating infectious diseases. Lancet Infect Dis 11: 702-712.
    • (2011) Lancet Infect Dis , vol.11 , pp. 702-712
    • Hedayat, M.1    Netea, M.G.2    Rezaei, N.3
  • 92
    • 17944371991 scopus 로고    scopus 로고
    • The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games
    • Hehlgans T, Pfeffer K, (2005) The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games. Immunology 115: 1-20.
    • (2005) Immunology , vol.115 , pp. 1-20
    • Hehlgans, T.1    Pfeffer, K.2
  • 93
    • 80051982064 scopus 로고    scopus 로고
    • Return to homeostasis: downregulation of NF-κB responses
    • Ruland J, (2011) Return to homeostasis: downregulation of NF-κB responses. Nat Immunol 12: 709-714.
    • (2011) Nat Immunol , vol.12 , pp. 709-714
    • Ruland, J.1
  • 94
    • 27544434183 scopus 로고    scopus 로고
    • Essential function for the kinase TAK1 in innate and adaptive immune responses
    • Sato S, Sanjo H, Takeda K, Ninomiya-Tsuji J, Yamamoto M, et al. (2005) Essential function for the kinase TAK1 in innate and adaptive immune responses. Nat Immunol 6: 1087-1095.
    • (2005) Nat Immunol , vol.6 , pp. 1087-1095
    • Sato, S.1    Sanjo, H.2    Takeda, K.3    Ninomiya-Tsuji, J.4    Yamamoto, M.5
  • 95
    • 4344670936 scopus 로고    scopus 로고
    • Bow ties, metabolism and disease
    • Csete M, Doyle J, (2004) Bow ties, metabolism and disease. Trends in Biotechnology 22: 446-450.
    • (2004) Trends in Biotechnology , vol.22 , pp. 446-450
    • Csete, M.1    Doyle, J.2
  • 96
    • 77952488171 scopus 로고    scopus 로고
    • Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNFalpha-induced inflammatory responses
    • Yang SK, Wang YC, Chao CC, Chuang YJ, Lan CY, et al. (2010) Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNFalpha-induced inflammatory responses. BMC Med Genomics 3: 19.
    • (2010) BMC Med Genomics , vol.3 , pp. 19
    • Yang, S.K.1    Wang, Y.C.2    Chao, C.C.3    Chuang, Y.J.4    Lan, C.Y.5
  • 97
    • 77951162860 scopus 로고    scopus 로고
    • Integrated cellular network of transcription regulations and protein-protein interactions
    • Wang YC, Chen BS, (2010) Integrated cellular network of transcription regulations and protein-protein interactions. BMC Syst Biol 4: 20.
    • (2010) BMC Syst Biol , vol.4 , pp. 20
    • Wang, Y.C.1    Chen, B.S.2
  • 98
    • 79958295844 scopus 로고    scopus 로고
    • Evolution of immune-neuroendocrine integration from an ecological immunology perspective
    • Ottaviani E, (2011) Evolution of immune-neuroendocrine integration from an ecological immunology perspective. Cell Tissue Res 344: 213-215.
    • (2011) Cell Tissue Res , vol.344 , pp. 213-215
    • Ottaviani, E.1
  • 99
    • 50249171872 scopus 로고    scopus 로고
    • Ecoimmunology: is there any room for the neuroendocrine system?
    • Ottaviani E, Malagoli D, Capri M, Franceschi C, (2008) Ecoimmunology: is there any room for the neuroendocrine system? Bioessays 30: 868-874.
    • (2008) Bioessays , vol.30 , pp. 868-874
    • Ottaviani, E.1    Malagoli, D.2    Capri, M.3    Franceschi, C.4
  • 100
    • 33745470929 scopus 로고    scopus 로고
    • Robustness trade-offs and host-microbial symbiosis in the immune system
    • 2006.0022
    • Kitano H, Oda K, (2006) Robustness trade-offs and host-microbial symbiosis in the immune system. Mol Syst Biol 2: 2006.0022.
    • (2006) Mol Syst Biol , vol.2
    • Kitano, H.1    Oda, K.2
  • 101
    • 77955371721 scopus 로고    scopus 로고
    • Network, degeneracy and bow tie integrating paradigms and architectures to grasp the complexity of the immune system
    • Tieri P, Grignolio A, Zaikin A, Mishto M, Remondini D, et al. (2010) Network, degeneracy and bow tie integrating paradigms and architectures to grasp the complexity of the immune system. Theor Biol Med Model 7: 32.
    • (2010) Theor Biol Med Model , vol.7 , pp. 32
    • Tieri, P.1    Grignolio, A.2    Zaikin, A.3    Mishto, M.4    Remondini, D.5
  • 103
    • 0028167599 scopus 로고
    • NF-kappa B activation of p53. A potential mechanism for suppressing cell growth in response to stress
    • Wu H, Lozano G, (1994) NF-kappa B activation of p53. A potential mechanism for suppressing cell growth in response to stress. J Biol Chem 269: 20067-20074.
    • (1994) J Biol Chem , vol.269 , pp. 20067-20074
    • Wu, H.1    Lozano, G.2
  • 104
    • 0033521099 scopus 로고    scopus 로고
    • Benzo[a]pyrene activates the human p53 gene through induction of nuclear factor kappaB activity
    • Pei XH, Nakanishi Y, Takayama K, Bai F, Hara N, (1999) Benzo[a]pyrene activates the human p53 gene through induction of nuclear factor kappaB activity. J Biol Chem 274: 35240-35246.
    • (1999) J Biol Chem , vol.274 , pp. 35240-35246
    • Pei, X.H.1    Nakanishi, Y.2    Takayama, K.3    Bai, F.4    Hara, N.5
  • 105
    • 0036020402 scopus 로고    scopus 로고
    • Estrogen up-regulation of p53 gene expression in MCF-7 breast cancer cells is mediated by calmodulin kinase IV-dependent activation of a nuclear factor kappaB/CCAAT-binding transcription factor-1 complex
    • Qin C, Nguyen T, Stewart J, Samudio I, Burghardt R, et al. (2002) Estrogen up-regulation of p53 gene expression in MCF-7 breast cancer cells is mediated by calmodulin kinase IV-dependent activation of a nuclear factor kappaB/CCAAT-binding transcription factor-1 complex. Mol Endocrinol 16: 1793-1809.
    • (2002) Mol Endocrinol , vol.16 , pp. 1793-1809
    • Qin, C.1    Nguyen, T.2    Stewart, J.3    Samudio, I.4    Burghardt, R.5
  • 106
    • 0034616639 scopus 로고    scopus 로고
    • p300/CBP-dependent and -independent transcriptional interference between NF-kappaB RelA and p53
    • Ikeda A, Sun X, Li Y, Zhang Y, Eckner R, et al. (2000) p300/CBP-dependent and-independent transcriptional interference between NF-kappaB RelA and p53. Biochem Biophys Res Commun 272: 375-379.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 375-379
    • Ikeda, A.1    Sun, X.2    Li, Y.3    Zhang, Y.4    Eckner, R.5
  • 107
    • 4444226454 scopus 로고    scopus 로고
    • HTLV-I Tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity
    • Jeong SJ, Radonovich M, Brady JN, Pise-Masison CA, (2004) HTLV-I Tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity. Blood 104: 1490-1497.
    • (2004) Blood , vol.104 , pp. 1490-1497
    • Jeong, S.J.1    Radonovich, M.2    Brady, J.N.3    Pise-Masison, C.A.4
  • 108
    • 0032532070 scopus 로고    scopus 로고
    • p53-mediated repression of nuclear factor-kappaB RelA via the transcriptional integrator p300
    • Ravi R, Mookerjee B, van Hensbergen Y, Bedi GC, Giordano A, et al. (1998) p53-mediated repression of nuclear factor-kappaB RelA via the transcriptional integrator p300. Cancer Res 58: 4531-4536.
    • (1998) Cancer Res , vol.58 , pp. 4531-4536
    • Ravi, R.1    Mookerjee, B.2    van Hensbergen, Y.3    Bedi, G.C.4    Giordano, A.5
  • 109
    • 77952424136 scopus 로고    scopus 로고
    • Cross talk between stimulated NF-kappaB and the tumor suppressor p53
    • Schneider G, Henrich A, Greiner G, Wolf V, Lovas A, et al. (2010) Cross talk between stimulated NF-kappaB and the tumor suppressor p53. Oncogene 29: 2795-2806.
    • (2010) Oncogene , vol.29 , pp. 2795-2806
    • Schneider, G.1    Henrich, A.2    Greiner, G.3    Wolf, V.4    Lovas, A.5
  • 110
    • 1642499403 scopus 로고    scopus 로고
    • Suppression of PTEN expression by NF-kappa B prevents apoptosis
    • Vasudevan KM, Gurumurthy S, Rangnekar VM, (2004) Suppression of PTEN expression by NF-kappa B prevents apoptosis. Mol Cell Biol 24: 1007-1021.
    • (2004) Mol Cell Biol , vol.24 , pp. 1007-1021
    • Vasudevan, K.M.1    Gurumurthy, S.2    Rangnekar, V.M.3
  • 111
    • 84857735480 scopus 로고    scopus 로고
    • Pten is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network
    • Ying H, Elpek KG, Vinjamoori A, Zimmerman SM, Chu GC, et al. (2011) Pten is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network. Cancer Discov 1: 158-169.
    • (2011) Cancer Discov , vol.1 , pp. 158-169
    • Ying, H.1    Elpek, K.G.2    Vinjamoori, A.3    Zimmerman, S.M.4    Chu, G.C.5
  • 112
    • 68149139538 scopus 로고    scopus 로고
    • The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology
    • Vereecke L, Beyaert R, van Loo G, (2009) The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology. Trends Immunol 30: 383-391.
    • (2009) Trends Immunol , vol.30 , pp. 383-391
    • Vereecke, L.1    Beyaert, R.2    van Loo, G.3
  • 113
    • 62849118323 scopus 로고    scopus 로고
    • Autoregulatory feedback loops terminating the NF-kappaB response
    • Renner F, Schmitz ML, (2009) Autoregulatory feedback loops terminating the NF-kappaB response. Trends Biochem Sci 34: 128-135.
    • (2009) Trends Biochem Sci , vol.34 , pp. 128-135
    • Renner, F.1    Schmitz, M.L.2
  • 114
    • 77951733865 scopus 로고    scopus 로고
    • Network strategies to understand the aging process and help age-related drug design
    • Simkó GI, Gyurkó D, Veres DV, Nánási T, Csermely P, (2009) Network strategies to understand the aging process and help age-related drug design. Genome Med 1: 90.
    • (2009) Genome Med , vol.1 , pp. 90
    • Simkó, G.I.1    Gyurkó, D.2    Veres, D.V.3    Nánási, T.4    Csermely, P.5
  • 115
    • 79953186033 scopus 로고    scopus 로고
    • HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination
    • Chen Y, Wang H, Yoon SO, Xu X, Hottiger MO, et al. (2011) HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nat Neurosci 14: 437-441.
    • (2011) Nat Neurosci , vol.14 , pp. 437-441
    • Chen, Y.1    Wang, H.2    Yoon, S.O.3    Xu, X.4    Hottiger, M.O.5
  • 116
    • 77955851183 scopus 로고    scopus 로고
    • Towards a matrix mechanics framework for dynamic protein network
    • Bhattacharya SK, (2010) Towards a matrix mechanics framework for dynamic protein network. Syst Synth Biol 4: 139-144.
    • (2010) Syst Synth Biol , vol.4 , pp. 139-144
    • Bhattacharya, S.K.1
  • 117
    • 43249116959 scopus 로고    scopus 로고
    • Understanding NF-kappaB signaling via mathematical modeling
    • Cheong R, Hoffmann A, Levchenko A, (2008) Understanding NF-kappaB signaling via mathematical modeling. Mol Syst Biol 4: 192.
    • (2008) Mol Syst Biol , vol.4 , pp. 192
    • Cheong, R.1    Hoffmann, A.2    Levchenko, A.3


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