Inducible degradation of IκBα by the proteasome requires interaction with the F-box protein h-βTrCP

Journal of Biological Chemistry

Volumn 274, Issue 12, 1999, Pages 7941-7945

  Kroll, Mathias ^a   Margottin, Florence ^b   Kohl, Alain ^a   Renard, Patricia ^a   Durand, Hervé ^b   Concordet, Jean Paul ^b   Bachelerie, Françoise ^a   Arenzana Seisdedos, Fernando ^a   Benarous, Richard ^b  

^a INSTITUT PASTEUR   (France)

^b INSTITUT COCHIN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGASE; NUCLEAR PROTEIN; PROTEASOME; PROTEIN BETA TRCP; SERINE; UBIQUITIN; UNCLASSIFIED DRUG; BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; BTRC PROTEIN, HUMAN; CELL CYCLE PROTEIN; CYSTEINE PROTEINASE; DNA BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; I KAPPA B; MULTIENZYME COMPLEX; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PEPTIDE SYNTHASE; S PHASE KINASE ASSOCIATED PROTEIN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REACTION ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION; BIOSYNTHESIS; CHEMICAL MODEL; GENETIC TRANSCRIPTION; GENETICS; HELA CELL; METABOLISM; PHOSPHORYLATION;

BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; CELL CYCLE PROTEINS; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; GTP-BINDING PROTEINS; HELA CELLS; HUMANS; I-KAPPA B PROTEINS; MODELS, CHEMICAL; MULTIENZYME COMPLEXES; NF-KAPPA B; PEPTIDE SYNTHASES; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; S-PHASE KINASE-ASSOCIATED PROTEINS; SERINE; SKP CULLIN F-BOX PROTEIN LIGASES; TRANSCRIPTION, GENETIC;

EID: 0033582821     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.12.7941     Document Type: Article

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