-
1
-
-
33646676272
-
Clinical practice. Acute pancreatitis
-
Whitcomb DC. (2006) Clinical practice. Acute pancreatitis. N. Engl. J. Med. 354:2142–50.
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 2142-2150
-
-
Whitcomb, D.C.1
-
2
-
-
77956392318
-
Etiology and diagnosis of acute biliary pancreatitis
-
van Geenen EJ, et al. (2010) Etiology and diagnosis of acute biliary pancreatitis. Nat. Rev. Gastroenterol. Hepatol. 7:495–502.
-
(2010)
Nat. Rev. Gastroenterol. Hepatol
, vol.7
, pp. 495-502
-
-
Van Geenen, E.J.1
-
3
-
-
34447629177
-
Alcohol consumption in patients with acute or chronic pancreatitis
-
Sand J, Lankisch PG, Nordback I. (2007) Alcohol consumption in patients with acute or chronic pancreatitis. Pancreatology. 7:147–56.
-
(2007)
Pancreatology
, vol.7
, pp. 147-156
-
-
Sand, J.1
Lankisch, P.G.2
Nordback, I.3
-
4
-
-
84871172866
-
Classification of acute pancreatitis— 2012: Revision of the Atlanta classification and definitions by international consensus
-
Banks PA, et al. (2013) Classification of acute pancreatitis— 2012: revision of the Atlanta classification and definitions by international consensus. Gut. 62:102–11.
-
(2013)
Gut
, vol.62
, pp. 102-111
-
-
Banks, P.A.1
-
5
-
-
68449099923
-
Acute pancreatitis: Risk of recurrence and late consequences of the disease
-
Sand J, Nordback I. (2009) Acute pancreatitis: risk of recurrence and late consequences of the disease. Nat. Rev. Gastroenterol. Hepatol. 6:470–7.
-
(2009)
Nat. Rev. Gastroenterol. Hepatol
, vol.6
, pp. 470-477
-
-
Sand, J.1
Nordback, I.2
-
6
-
-
84876792209
-
Clinical management of patients with acute pancreatitis
-
Wu BU, Banks PA. (2013) Clinical management of patients with acute pancreatitis. Gastroenterology. 144:1272–81.
-
(2013)
Gastroenterology
, vol.144
, pp. 1272-1281
-
-
Wu, B.U.1
Banks, P.A.2
-
7
-
-
84872301470
-
Fluid therapy in acute pancreatitis: Anybody’s guess
-
Haydock MD, et al. (2013) Fluid therapy in acute pancreatitis: anybody’s guess. Ann. Surg. 257:182–8.
-
(2013)
Ann. Surg
, vol.257
, pp. 182-188
-
-
Haydock, M.D.1
-
8
-
-
84876813879
-
Genetic risk factors for pancreatic disorders
-
Whitcomb DC. (2013) Genetic risk factors for pancreatic disorders. Gastroenterology. 144:1292–302.
-
(2013)
Gastroenterology
, vol.144
, pp. 1292-1302
-
-
Whitcomb, D.C.1
-
10
-
-
79959983521
-
TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis
-
Hoque R, et al. (2011) TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis. Gastroenterology. 141:358–69.
-
(2011)
Gastroenterology
, vol.141
, pp. 358-369
-
-
Hoque, R.1
-
11
-
-
84896478042
-
Intracellular hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice
-
Kang R, et al. (2014) Intracellular hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice. Gastroenterology. 146:1097–107.
-
(2014)
Gastroenterology
, vol.146
, pp. 1097-1107
-
-
Kang, R.1
-
12
-
-
77950366886
-
Decoding cell death signals in inflammation and immunity
-
Zitvogel L, Kepp O, Kroemer G. (2010) Decoding cell death signals in inflammation and immunity. Cell. 140:798–804.
-
(2010)
Cell
, vol.140
, pp. 798-804
-
-
Zitvogel, L.1
Kepp, O.2
Kroemer, G.3
-
13
-
-
33845951211
-
DAMPs, PAMPs and alarmins: All we need to know about danger
-
Bianchi ME. (2007) DAMPs, PAMPs and alarmins: all we need to know about danger. J. Leukoc. Biol. 81:1–5.
-
(2007)
J. Leukoc. Biol
, vol.81
, pp. 1-5
-
-
Bianchi, M.E.1
-
14
-
-
84865299726
-
PAMPs and DAMPs: Signal 0s that spur autophagy and immunity
-
Tang D, et al. (2012) PAMPs and DAMPs: signal 0s that spur autophagy and immunity. Immunol. Rev. 249:158–75.
-
(2012)
Immunol. Rev
, vol.249
, pp. 158-175
-
-
Tang, D.1
-
15
-
-
84876788888
-
Models of acute and chronic pancreatitis
-
Lerch MM, Gorelick FS. (2013) Models of acute and chronic pancreatitis. Gastroenterology. 144:1180–93.
-
(2013)
Gastroenterology
, vol.144
, pp. 1180-1193
-
-
Lerch, M.M.1
Gorelick, F.S.2
-
16
-
-
84876794306
-
Relevance of animal models of pancreatic cancer and pancreatitis to human disease
-
Saluja AK, Dudeja V. (2013) Relevance of animal models of pancreatic cancer and pancreatitis to human disease. Gastroenterology. 144:1194–8.
-
(2013)
Gastroenterology
, vol.144
, pp. 1194-1198
-
-
Saluja, A.K.1
Dudeja, V.2
-
17
-
-
84865521139
-
Pathogenic mechanisms of acute pancreatitis. Curr. Opin
-
Sah RP, Garg P, Saluja AK. (2012) Pathogenic mechanisms of acute pancreatitis. Curr. Opin. Gastroenterol. 28:507–15.
-
(2012)
Gastroenterol
, vol.28
, pp. 507-515
-
-
Sah, R.P.1
Garg, P.2
Saluja, A.K.3
-
19
-
-
81855228093
-
Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis
-
Dawra R, et al. (2011) Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis. Gastroenterology. 141:2210–7.
-
(2011)
Gastroenterology
, vol.141
, pp. 2210-2217
-
-
Dawra, R.1
-
20
-
-
0031836766
-
Oxidative stress: An important phenomenon with pathogenetic significance in the progression of acute pancreatitis
-
Tsai K, et al. (1998) Oxidative stress: an important phenomenon with pathogenetic significance in the progression of acute pancreatitis. Gut. 42:850–5.
-
(1998)
Gut
, vol.42
, pp. 850-855
-
-
Tsai, K.1
-
21
-
-
84865259804
-
The role of calcium in acute pancreatitis
-
Frick TW. (2012) The role of calcium in acute pancreatitis. Surgery. 152:S157–63.
-
(2012)
Surgery
, vol.152
, pp. 157-163
-
-
Frick, T.W.1
-
23
-
-
69249117460
-
Reducing extracellular pH sensitizes the acinar cell to secretagogue- induced pancreatitis responses in rats
-
Bhoomagoud M, et al. (2009) Reducing extracellular pH sensitizes the acinar cell to secretagogue- induced pancreatitis responses in rats. Gastroenterology. 137:1083–92.
-
(2009)
Gastroenterology
, vol.137
, pp. 1083-1092
-
-
Bhoomagoud, M.1
-
24
-
-
79958177198
-
Which way to die: The regulation of acinar cell death in pancreatitis by mitochondria, calcium, and reactive oxygen species
-
Gukovskaya AS, Gukovsky I. (2011) Which way to die: the regulation of acinar cell death in pancreatitis by mitochondria, calcium, and reactive oxygen species. Gastroenterology. 140:1876–80.
-
(2011)
Gastroenterology
, vol.140
, pp. 1876-1880
-
-
Gukovskaya, A.S.1
Gukovsky, I.2
-
25
-
-
33745785456
-
Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis. Am. J. Physiol. Gastrointest
-
Kubisch CH, et al. (2006) Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis. Am. J. Physiol. Gastrointest. Liver Physiol. 291:G238–45.
-
(2006)
Liver Physiol
, vol.291
, pp. 238-245
-
-
Kubisch, C.H.1
-
27
-
-
0036007501
-
NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response
-
Chen X, et al. (2002) NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response. Gastroenterology. 122:448–57.
-
(2002)
Gastroenterology
, vol.122
, pp. 448-457
-
-
Chen, X.1
-
28
-
-
84871282951
-
Deletion of IkappaBalpha activates RelA to reduce acute pancreatitis in mice through up-regulation of Spi2A
-
Neuhofer P, et al. (2012) Deletion of IkappaBalpha activates RelA to reduce acute pancreatitis in mice through up-regulation of Spi2A. Gastroenterology. 144:192–201.
-
(2012)
Gastroenterology
, vol.144
, pp. 192-201
-
-
Neuhofer, P.1
-
29
-
-
84871272183
-
Activation of nuclear factorkappaB in acinar cells increases the severity of pancreatitis in mice
-
Huang H, et al. (2012) Activation of nuclear factorkappaB in acinar cells increases the severity of pancreatitis in mice. Gastroenterology. 144:202–10.
-
(2012)
Gastroenterology
, vol.144
, pp. 202-210
-
-
Huang, H.1
-
30
-
-
38549084647
-
The role of NFkappaB activation in the pathogenesis of acute pancreatitis
-
Rakonczay Z Jr, et al. (2008) The role of NFkappaB activation in the pathogenesis of acute pancreatitis. Gut. 57:259–67.
-
(2008)
Gut
, vol.57
, pp. 259-267
-
-
Rakonczay, Z.1
-
31
-
-
80055081322
-
Role of neutrophils in the activation of trypsinogen in severe acute pancreatitis
-
Abdulla A, Awla D, Thorlacius H, Regner S. (2011) Role of neutrophils in the activation of trypsinogen in severe acute pancreatitis. J. Leukoc. Biol. 90:975–82.
-
(2011)
J. Leukoc. Biol
, vol.90
, pp. 975-982
-
-
Abdulla, A.1
Awla, D.2
Thorlacius, H.3
Regner, S.4
-
32
-
-
84874606609
-
IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality
-
Zhang H, et al. (2013) IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality. J. Clin. Invest. 123:1019–31.
-
(2013)
J. Clin. Invest
, vol.123
, pp. 1019-1031
-
-
Zhang, H.1
-
33
-
-
84255210700
-
Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death
-
Galluzzi L, et al. (2012) Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ. 19:107–20.
-
(2012)
Cell Death Differ
, vol.19
, pp. 107-120
-
-
Galluzzi, L.1
-
34
-
-
1642498302
-
Apoptosis versus necrosis in acute pancreatitis. Am. J. Physiol. Gastrointest
-
Bhatia M. (2004) Apoptosis versus necrosis in acute pancreatitis. Am. J. Physiol. Gastrointest. Liver Physiol. 286:G189–96.
-
(2004)
Liver Physiol
, vol.286
, pp. 189-196
-
-
Bhatia, M.1
-
35
-
-
0028783295
-
Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis
-
Kaiser AM, et al. (1995) Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis. Am. J. Physiol. 269:C1295–304.
-
(1995)
Am. J. Physiol
, vol.269
, pp. 1295-1304
-
-
Kaiser, A.M.1
-
36
-
-
84872466790
-
Eat-me: Autophagy, phagocytosis, and reactive oxygen species signaling
-
Vernon PJ, Tang D. (2013) Eat-me: autophagy, phagocytosis, and reactive oxygen species signaling. Antioxid. Redox. Signal 18:677–91.
-
(2013)
Antioxid. Redox. Signal
, vol.18
, pp. 677-691
-
-
Vernon, P.J.1
Tang, D.2
-
37
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
Shimada K, et al. (2012) Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity. 36:401–14.
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
-
38
-
-
84859708101
-
The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation
-
McGill MR, et al. (2012) The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation. J. Clin. Invest. 122:1574–83.
-
(2012)
J. Clin. Invest
, vol.122
, pp. 1574-1583
-
-
Mc Gill, M.R.1
-
39
-
-
61749099391
-
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome
-
Imaeda AB, et al. (2009) Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome. J. Clin. Invest. 119:305–14.
-
(2009)
J. Clin. Invest
, vol.119
, pp. 305-314
-
-
Imaeda, A.B.1
-
40
-
-
29944438881
-
Necrotic death as a cell fate
-
Zong WX, Thompson CB. (2006) Necrotic death as a cell fate. Genes. Dev. 20:1–15.
-
(2006)
Genes. Dev
, vol.20
, pp. 1-15
-
-
Zong, W.X.1
Thompson, C.B.2
-
41
-
-
84887485264
-
Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis
-
Gu H, et al. (2013) Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis. Cell Death Dis. 4:e816.
-
(2013)
Cell Death Dis
, vol.4
-
-
Gu, H.1
-
42
-
-
34547105307
-
Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus
-
Ditsworth D, Zong WX, Thompson CB. (2007) Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus. J. Biol. Chem. 282:17845–54.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 17845-17854
-
-
Ditsworth, D.1
Zong, W.X.2
Thompson, C.B.3
-
43
-
-
25144433997
-
Inhibition of poly(ADPribose) polymerase attenuates the severity of acute pancreatitis and associated lung injury
-
Mota RA, et al. (2005) Inhibition of poly(ADPribose) polymerase attenuates the severity of acute pancreatitis and associated lung injury. Lab. Invest. 85:1250–62.
-
(2005)
Lab. Invest
, vol.85
, pp. 1250-1262
-
-
Mota, R.A.1
-
44
-
-
34250698918
-
Calcium signalling and pancreatic cell death: Apoptosis or necrosis?
-
Criddle DN, et al. (2007) Calcium signalling and pancreatic cell death: apoptosis or necrosis? Cell Death Differ. 14:1285–94.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1285-1294
-
-
Criddle, D.N.1
-
45
-
-
23844450083
-
Potential role of reactive oxygen species in pancreatitis- associated multiple organ dysfunction
-
Shi C, Andersson R, Zhao X, Wang X. (2005) Potential role of reactive oxygen species in pancreatitis- associated multiple organ dysfunction. Pancreatology. 5:492–500.
-
(2005)
Pancreatology
, vol.5
, pp. 492-500
-
-
Shi, C.1
Andersson, R.2
Zhao, X.3
Wang, X.4
-
46
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO. (2000) The biochemistry of apoptosis. Nature. 407:770–6.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
47
-
-
8444220527
-
Molecular mechanisms of caspase regulation during apoptosis
-
Riedl SJ, Shi Y. (2004) Molecular mechanisms of caspase regulation during apoptosis. Nat. Rev. Mol. Cell. Biol. 5:897–907.
-
(2004)
Nat. Rev. Mol. Cell. Biol
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
-
48
-
-
37549048249
-
The BCL-2 protein family: Opposing activities that mediate cell death
-
Youle RJ, Strasser A. (2008) The BCL-2 protein family: opposing activities that mediate cell death. Nature Rev. Mol. Cell Biol. 9:47–59.
-
(2008)
Nature Rev. Mol. Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
49
-
-
3943071150
-
Cytochrome C-mediated apoptosis
-
Jiang X, Wang X. (2004) Cytochrome C-mediated apoptosis. Annu. Rev. Biochem. 73:87–106.
-
(2004)
Annu. Rev. Biochem
, vol.73
, pp. 87-106
-
-
Jiang, X.1
Wang, X.2
-
50
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C, et al. (2000) Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell. 102:33–42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
-
51
-
-
0030025675
-
Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat
-
Gukovskaya AS, et al. (1996) Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat. Gastroenterology. 110:875–84.
-
(1996)
Gastroenterology
, vol.110
, pp. 875-884
-
-
Gukovskaya, A.S.1
-
52
-
-
34250833401
-
Induction of apoptosis by crambene protects mice against acute pancreatitis via anti-inflammatory pathways
-
Cao Y, et al. (2007) Induction of apoptosis by crambene protects mice against acute pancreatitis via anti-inflammatory pathways. Am. J. Pathol. 170:1521–34.
-
(2007)
Am. J. Pathol
, vol.170
, pp. 1521-1534
-
-
Cao, Y.1
-
53
-
-
79958157501
-
Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells
-
Booth DM, et al. (2011) Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells. Gastroenterology. 140:2116–25.
-
(2011)
Gastroenterology
, vol.140
, pp. 2116-2125
-
-
Booth, D.M.1
-
54
-
-
33645640921
-
Cell death in pancreatitis: Caspases protect from necrotizing pancreatitis
-
Mareninova OA, et al. (2006) Cell death in pancreatitis: caspases protect from necrotizing pancreatitis. J. Biol. Chem. 281:3370–81.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 3370-3381
-
-
Mareninova, O.A.1
-
55
-
-
0037151017
-
Cholecystokinin induces caspase activation and mitochondrial dysfunction in pancreatic acinar cells. Roles in cell injury processes of pancreatitis
-
Gukovskaya AS, et al. (2002) Cholecystokinin induces caspase activation and mitochondrial dysfunction in pancreatic acinar cells. Roles in cell injury processes of pancreatitis. J. Biol. Chem. 277:22595–604.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 22595-22604
-
-
Gukovskaya, A.S.1
-
56
-
-
0036143683
-
Thermal stress-induced HSP70 mediates protection against intrapancreatic trypsinogen activation and acute pancreatitis in rats
-
Bhagat L, et al. (2002) Thermal stress-induced HSP70 mediates protection against intrapancreatic trypsinogen activation and acute pancreatitis in rats. Gastroenterology. 122:156–65.
-
(2002)
Gastroenterology
, vol.122
, pp. 156-165
-
-
Bhagat, L.1
-
57
-
-
0036135383
-
Both thermal and nonthermal stress protect against caerulein induced pancreatitis and prevent trypsinogen activation in the pancreas
-
Frossard JL, et al. (2002) Both thermal and nonthermal stress protect against caerulein induced pancreatitis and prevent trypsinogen activation in the pancreas. Gut. 50:78–83.
-
(2002)
Gut
, vol.50
, pp. 78-83
-
-
Frossard, J.L.1
-
58
-
-
20444377309
-
Significance of apoptotic cell death in systemic complications with severe acute pancreatitis
-
Takeyama Y. (2005) Significance of apoptotic cell death in systemic complications with severe acute pancreatitis. J. Gastroenterol. 40:1–10.
-
(2005)
J. Gastroenterol
, vol.40
, pp. 1-10
-
-
Takeyama, Y.1
-
59
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky DJ, Emr SD. (2000) Autophagy as a regulated pathway of cellular degradation. Science. 290:1717–21.
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
60
-
-
56749170677
-
Autophagic cell death: The story of a misnomer
-
Kroemer G, Levine B. (2008) Autophagic cell death: the story of a misnomer. Nat. Rev. Mol. Cell. Biol. 9:1004–10.
-
(2008)
Nat. Rev. Mol. Cell. Biol
, vol.9
, pp. 1004-1010
-
-
Kroemer, G.1
Levine, B.2
-
61
-
-
57649217868
-
Autophagy regulates selective HMGB1 release in tumor cells that are destined to die
-
Thorburn J, et al. (2009) Autophagy regulates selective HMGB1 release in tumor cells that are destined to die. Cell Death Differ. 16:175–83.
-
(2009)
Cell Death Differ
, vol.16
, pp. 175-183
-
-
Thorburn, J.1
-
62
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine B, Mizushima N, Virgin HW. (2011) Autophagy in immunity and inflammation. Nature. 469:323–35.
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
63
-
-
84891754287
-
Strange attractors: DAMPs and autophagy link tumor cell death and immunity
-
Hou W, et al. (2013) Strange attractors: DAMPs and autophagy link tumor cell death and immunity. Cell Death Dis. 4:e966.
-
(2013)
Cell Death Dis
, pp. 4
-
-
Hou, W.1
-
64
-
-
84877328234
-
DAMPs and autophagy: Cellular adaptation to injury and unscheduled cell death
-
Zhang Q, et al. (2013) DAMPs and autophagy: cellular adaptation to injury and unscheduled cell death. Autophagy. 9:451–8.
-
(2013)
Autophagy
, vol.9
, pp. 451-458
-
-
Zhang, Q.1
-
65
-
-
84876796439
-
Inflammation, autophagy, and obesity: Common features in the pathogenesis of pancreatitis and pancreatic cancer
-
Gukovsky I, et al. (2013) Inflammation, autophagy, and obesity: common features in the pathogenesis of pancreatitis and pancreatic cancer. Gastroenterology. 144:1199–209.
-
(2013)
Gastroenterology
, vol.144
, pp. 1199-1209
-
-
Gukovsky, I.1
-
66
-
-
84856948227
-
Impaired autophagy and organellar dysfunction in pancreatitis
-
Gukovsky I, et al. (2012) Impaired autophagy and organellar dysfunction in pancreatitis. J. Gastroenterol. Hepatol. 27 Suppl 2:27–32.
-
(2012)
J. Gastroenterol. Hepatol. 27 Suppl
, vol.2
, pp. 27-32
-
-
Gukovsky, I.1
-
67
-
-
70449426665
-
Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis
-
Mareninova OA, et al. (2009) Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis. J. Clin. Invest. 119:3340–55.
-
(2009)
J. Clin. Invest
, vol.119
, pp. 3340-3355
-
-
Mareninova, O.A.1
-
68
-
-
46249114022
-
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells. J
-
Hashimoto D, et al. (2008) Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells. J. Cell Biol. 181:1065–72.
-
(2008)
Cell Biol
, vol.181
, pp. 1065-1072
-
-
Hashimoto, D.1
-
69
-
-
84868378549
-
Autophagy and pancreatitis. Am. J. Physiol. Gastrointest
-
Gukovskaya AS, Gukovsky I. (2012) Autophagy and pancreatitis. Am. J. Physiol. Gastrointest. Liver Physiol. 303:G993-G1003.
-
(2012)
Liver Physiol
, vol.303
, pp. G993-G1003
-
-
Gukovskaya, A.S.1
Gukovsky, I.2
-
70
-
-
67649382475
-
Impaired autolysosome formation correlates with Lamp-2 depletion: Role of apoptosis, autophagy, and necrosis in pancreatitis
-
Fortunato F, et al. (2009) Impaired autolysosome formation correlates with Lamp-2 depletion: role of apoptosis, autophagy, and necrosis in pancreatitis. Gastroenterology. 137:350–60, 360 e1–5.
-
(2009)
Gastroenterology
, vol.137
, pp. 350-360
-
-
Fortunato, F.1
-
71
-
-
79953144994
-
Zymophagy, a novel selective autophagy pathway mediated by VMP1- USP9x-p62, prevents pancreatic cell death
-
Grasso D, et al. (2011) Zymophagy, a novel selective autophagy pathway mediated by VMP1- USP9x-p62, prevents pancreatic cell death. J. Biol. Chem. 286:8308–24.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 8308-8324
-
-
Grasso, D.1
-
72
-
-
37549012209
-
The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells
-
Ropolo A, et al. (2007) The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells. J. Biol. Chem. 282:37124–33.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 37124-37133
-
-
Ropolo, A.1
-
73
-
-
84872799206
-
The VMP1-Beclin 1 interaction regulates autophagy induction
-
Molejon MI, et al. (2013) The VMP1-Beclin 1 interaction regulates autophagy induction. Sci. Rep. 3:1055.
-
(2013)
Sci. Rep
, vol.3
, pp. 1055
-
-
Molejon, M.I.1
-
74
-
-
79952628267
-
The Beclin 1 network regulates autophagy and apoptosis
-
Kang R, Zeh HJ, Lotze MT, Tang D. (2011) The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ. 18:571–80.
-
(2011)
Cell Death Differ
, vol.18
, pp. 571-580
-
-
Kang, R.1
Zeh, H.J.2
Lotze, M.T.3
Tang, D.4
-
75
-
-
84866345751
-
Role of intrapancreatic SPINK1/Spink3 expression in the development of pancreatitis
-
Ohmuraya M, et al. (2012) Role of intrapancreatic SPINK1/Spink3 expression in the development of pancreatitis. Front Physiol. 3:126.
-
(2012)
Front Physiol
, vol.3
, pp. 126
-
-
Ohmuraya, M.1
-
78
-
-
84862907788
-
Mixed lineage kinase domainlike protein mediates necrosis signaling downstream of RIP3 kinase
-
Sun L, et al. (2012) Mixed lineage kinase domainlike protein mediates necrosis signaling downstream of RIP3 kinase. Cell. 148:213–27.
-
(2012)
Cell
, vol.148
, pp. 213-227
-
-
Sun, L.1
-
79
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev A, et al. (2005) Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat. Chem. Biol. 1:112–9.
-
(2005)
Nat. Chem. Biol
, vol.1
, pp. 112-119
-
-
Degterev, A.1
-
80
-
-
66749183275
-
Receptor interacting protein kinase- 3 determines cellular necrotic response to TNF-alpha
-
He S, et al. (2009) Receptor interacting protein kinase- 3 determines cellular necrotic response to TNF-alpha. Cell. 137:1100–11.
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
-
81
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang DW, et al. (2009) RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science. 325:332–6.
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
-
82
-
-
84255162797
-
RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome
-
Duprez L, et al. (2011) RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome. Immunity. 35:908–18.
-
(2011)
Immunity
, vol.35
, pp. 908-918
-
-
Duprez, L.1
-
83
-
-
84874263775
-
Necroptosis: The release of damage-associated molecular patterns and its physiological relevance
-
Kaczmarek A, Vandenabeele P, Krysko DV. (2013) Necroptosis: the release of damage-associated molecular patterns and its physiological relevance. Immunity. 38:209–23.
-
(2013)
Immunity
, vol.38
, pp. 209-223
-
-
Kaczmarek, A.1
Vandenabeele, P.2
Krysko, D.V.3
-
84
-
-
84862175306
-
Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-alpha-induced shock
-
Linkermann A, et al. (2012) Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-alpha-induced shock. Mol. Med. 18:577–86.
-
(2012)
Mol. Med
, vol.18
, pp. 577-586
-
-
Linkermann, A.1
-
85
-
-
0033815330
-
Salmonella induces macrophage death by caspase-1-dependent necrosis
-
Brennan MA, Cookson BT. (2000) Salmonella induces macrophage death by caspase-1-dependent necrosis. Mol. Microbiol. 38:31–40.
-
(2000)
Mol. Microbiol
, vol.38
, pp. 31-40
-
-
Brennan, M.A.1
Cookson, B.T.2
-
87
-
-
84883367417
-
Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury
-
Huang H, et al. (2013) Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury. J. Immunol. 191:2665–79.
-
(2013)
J. Immunol
, vol.191
, pp. 2665-2679
-
-
Huang, H.1
-
88
-
-
84905053185
-
Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis
-
Xu J, et al. (2014) Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis. Cell Death Differ. 21:1229-39.
-
(2014)
Cell Death Differ
, vol.21
, pp. 1229-1239
-
-
Xu, J.1
-
89
-
-
80051969149
-
Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice
-
Huang H, et al. (2011) Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice. Hepatology. 54:999–1008.
-
(2011)
Hepatology
, vol.54
, pp. 999-1008
-
-
Huang, H.1
-
90
-
-
77950362382
-
The inflammasomes
-
Schroder K, Tschopp J. (2010) The inflammasomes. Cell. 140:821–32.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
91
-
-
34250837518
-
A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA
-
Ivanov S, et al. (2007) A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA. Blood. 110:1970–81.
-
(2007)
Blood
, vol.110
, pp. 1970-1981
-
-
Ivanov, S.1
-
92
-
-
77955403878
-
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release
-
Yang H, et al. (2010) A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release. Proc. Natl. Acad. Sci. U. S. A. 107:11942–7.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A
, vol.107
, pp. 11942-11947
-
-
Yang, H.1
-
93
-
-
84907218485
-
HMGB1-DNA complex-induced autophagy limits AIM2 inflammasome activation through RAGE
-
Liu L, et al. (2014) HMGB1-DNA complex-induced autophagy limits AIM2 inflammasome activation through RAGE. Biochem. Biophys. Res. Commun. 450:851–6.
-
(2014)
Biochem. Biophys. Res. Commun
, vol.450
, pp. 851-856
-
-
Liu, L.1
-
95
-
-
84868148599
-
PKR-dependent inflammatory signals
-
Kang R, Tang D. (2012) PKR-dependent inflammatory signals. Sci. Signal. 5:pe47.
-
(2012)
Sci. Signal
, vol.5
-
-
Kang, R.1
Tang, D.2
-
96
-
-
79953068336
-
Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation
-
Krysko DV, et al. (2011) Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation. Trends Immunol. 32:157–64.
-
(2011)
Trends Immunol
, vol.32
, pp. 157-164
-
-
Krysko, D.V.1
-
97
-
-
84893245205
-
The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics
-
Kang R, et al. (2014) The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics. Oncogene. 33:567–77.
-
(2014)
Oncogene
, vol.33
, pp. 567-577
-
-
Kang, R.1
-
98
-
-
48749124996
-
High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage
-
Lange SS, Mitchell DL, Vasquez KM. (2008) High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage. Proc. Natl. Acad. Sci. U. S. A. 105:10320–5.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A
, vol.105
, pp. 10320-10325
-
-
Lange, S.S.1
Mitchell, D.L.2
Vasquez, K.M.3
-
99
-
-
77956386515
-
Endogenous HMGB1 regulates autophagy
-
Tang D, et al. (2010) Endogenous HMGB1 regulates autophagy. J. Cell Biol. 190:881–92.
-
(2010)
J. Cell Biol
, vol.190
, pp. 881-892
-
-
Tang, D.1
-
100
-
-
0033538467
-
HMG-1 as a late mediator of endotoxin lethality in mice
-
Wang H, et al. (1999) HMG-1 as a late mediator of endotoxin lethality in mice. Science. 285:248–51.
-
(1999)
Science
, vol.285
, pp. 248-251
-
-
Wang, H.1
-
101
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi P, Misteli T, Bianchi ME. (2002) Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature. 418:191–5.
-
(2002)
Nature
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
102
-
-
46749136790
-
Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein
-
Kazama H, et al. (2008) Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein. Immunity. 29:21–32.
-
(2008)
Immunity
, vol.29
, pp. 21-32
-
-
Kazama, H.1
-
103
-
-
84865511926
-
Novel role of PKR in inflammasome activation and HMGB1 release
-
Lu B, et al. (2012) Novel role of PKR in inflammasome activation and HMGB1 release. Nature. 488:670–4.
-
(2012)
Nature
, vol.488
, pp. 670-674
-
-
Lu, B.1
-
104
-
-
77956386515
-
Endogenous HMGB1 regulates autophagy
-
Tang D, et al. (2010) Endogenous HMGB1 regulates autophagy. J. Cell Biol. 190:881–892.
-
(2010)
J. Cell Biol
, vol.190
, pp. 881-892
-
-
Tang, D.1
-
105
-
-
84881231803
-
HMGB1 in cancer: Good, bad, or both?
-
Kang R, et al. (2013) HMGB1 in cancer: good, bad, or both? Clin, Cancer Res. 19:4046–57.
-
(2013)
Clin, Cancer Res
, vol.19
, pp. 4046-4057
-
-
Kang, R.1
-
106
-
-
84866378556
-
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release
-
Venereau E, et al. (2012) Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release. J. Exp. Med. 209:1519–28.
-
(2012)
J. Exp. Med
, vol.209
, pp. 1519-1528
-
-
Venereau, E.1
-
107
-
-
77957106729
-
HMGB1 release and redox regulates autophagy and apoptosis in cancer cells
-
Tang D, et al. (2010) HMGB1 release and redox regulates autophagy and apoptosis in cancer cells. Oncogene. 29:5299–310.
-
(2010)
Oncogene
, vol.29
, pp. 5299-5310
-
-
Tang, D.1
-
108
-
-
84870781509
-
A Janus tale of two active HMGB1 redox states
-
Tang D, Billiar TA, Lotze MT. (2012) A Janus tale of two active HMGB1 redox states. Mol. Med. 18:1360–2.
-
(2012)
Mol. Med
, vol.18
, pp. 1360-1362
-
-
Tang, D.1
Billiar, T.A.2
Lotze, M.T.3
-
109
-
-
84908448181
-
HMGB1 in health and disease
-
Kang R, et al. (2014) HMGB1 in health and disease. Mol. Aspects Med. 2014, July 8 [Epub ahead of print].
-
(2014)
Mol. Aspects Med
, vol.2014
-
-
Kang, R.1
-
110
-
-
33750608337
-
Significant increase of serum high-mobility group box chromosomal protein 1 levels in patients with severe acute pancreatitis
-
Yasuda T, et al. (2006) Significant increase of serum high-mobility group box chromosomal protein 1 levels in patients with severe acute pancreatitis. Pancreas. 33:359–63.
-
(2006)
Pancreas
, vol.33
, pp. 359-363
-
-
Yasuda, T.1
-
111
-
-
58049093658
-
Delayed ethyl pyruvate therapy attenuates experimental severe acute pancreatitis via reduced serum high mobility group box 1 levels in rats. World J
-
Yang ZY, et al. (2008) Delayed ethyl pyruvate therapy attenuates experimental severe acute pancreatitis via reduced serum high mobility group box 1 levels in rats. World J. Gastroenterol. 14:4546–50.
-
(2008)
Gastroenterol
, vol.14
, pp. 4546-4550
-
-
Yang, Z.Y.1
-
112
-
-
65349151882
-
Protective effect of HMGB1 a box on organ injury of acute pancreatitis in mice
-
Yuan H, et al. (2009) Protective effect of HMGB1 a box on organ injury of acute pancreatitis in mice. Pancreas. 38:143–8.
-
(2009)
Pancreas
, vol.38
, pp. 143-148
-
-
Yuan, H.1
-
113
-
-
33845989093
-
Blockade of high mobility group box-1 protein attenuates experimental severe acute pancreatitis
-
Sawa H, et al. (2006) Blockade of high mobility group box-1 protein attenuates experimental severe acute pancreatitis. World J. Gastroenterol. 12:7666–70.
-
(2006)
World J. Gastroenterol
, vol.12
, pp. 7666-7670
-
-
Sawa, H.1
-
114
-
-
77956188219
-
Antioxidant inhibits HMGB1 expression and reduces pancreas injury in rats with severe acute pancreatitis
-
Zhang ZW, et al. (2010) Antioxidant inhibits HMGB1 expression and reduces pancreas injury in rats with severe acute pancreatitis. Dig. Dis. Sci. 55:2529–36.
-
(2010)
Dig. Dis. Sci
, vol.55
, pp. 2529-2536
-
-
Zhang, Z.W.1
-
115
-
-
70349897475
-
Antithrombin III prevents cerulein-induced acute pancreatitis in rats
-
Hagiwara S, et al. (2009) Antithrombin III prevents cerulein-induced acute pancreatitis in rats. Pancreas. 38:746–51.
-
(2009)
Pancreas
, vol.38
, pp. 746-751
-
-
Hagiwara, S.1
-
116
-
-
67749086619
-
Danaparoid sodium prevents cerulein-induced acute pancreatitis in rats
-
Hagiwara S, et al. (2009) Danaparoid sodium prevents cerulein-induced acute pancreatitis in rats. Shock. 32:94–9.
-
(2009)
Shock
, vol.32
, pp. 94-99
-
-
Hagiwara, S.1
-
117
-
-
84907375442
-
High mobility group box 1 (HMGB1) phenotypic role revealed with stress
-
Tang D, et al. (2014) High mobility group box 1 (HMGB1) phenotypic role revealed with stress. Mol. Med. 2014;20:359–62.
-
(2014)
Mol. Med. 2014
, vol.20
, pp. 359-362
-
-
Tang, D.1
-
118
-
-
84864318195
-
Chaperonemediated autophagy: A unique way to enter the lysosome world
-
Kaushik S, Cuervo AM. (2012) Chaperonemediated autophagy: a unique way to enter the lysosome world. Trends Cell Biol. 22:407–17.
-
(2012)
Trends Cell Biol
, vol.22
, pp. 407-417
-
-
Kaushik, S.1
Cuervo, A.M.2
-
119
-
-
79958050965
-
High-mobility group box 1 is essential for mitochondrial quality control
-
Tang D, et al. (2011) High-mobility group box 1 is essential for mitochondrial quality control. Cell Metab. 13:701–11.
-
(2011)
Cell Metab
, vol.13
, pp. 701-711
-
-
Tang, D.1
-
120
-
-
81255214620
-
Heat shock protein 72 enhances autophagy as a protective mechanism in lipopolysaccharide-induced peritonitis in rats
-
Li S, et al. (2011) Heat shock protein 72 enhances autophagy as a protective mechanism in lipopolysaccharide-induced peritonitis in rats. Am. J. Pathol. 179:2822–34.
-
(2011)
Am. J. Pathol
, vol.179
, pp. 2822-2834
-
-
Li, S.1
-
121
-
-
33947491607
-
Flagellin contamination of recombinant heat shock protein 70 is responsible for its activity on T cells
-
Ye Z, Gan YH. (2007) Flagellin contamination of recombinant heat shock protein 70 is responsible for its activity on T cells. J. Biol. Chem. 282:4479–84.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 4479-4484
-
-
Ye, Z.1
Gan, Y.H.2
-
122
-
-
0037414787
-
Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release by murine macrophages
-
Gao B, Tsan MF. (2003) Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release by murine macrophages. J. Biol. Chem. 278:174–9.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 174-179
-
-
Gao, B.1
Tsan, M.F.2
-
123
-
-
0034913246
-
Arginine induced acute pancreatitis alters the actin cytoskeleton and increases heat shock protein expression in rat pancreatic acinar cells
-
Tashiro M, et al. (2001) Arginine induced acute pancreatitis alters the actin cytoskeleton and increases heat shock protein expression in rat pancreatic acinar cells. Gut. 49:241–50.
-
(2001)
Gut
, vol.49
, pp. 241-250
-
-
Tashiro, M.1
-
124
-
-
0033798620
-
Acute pancreatitis results in induction of heat shock proteins 70 and 27 and heat shock factor-1
-
Ethridge RT, et al. (2000) Acute pancreatitis results in induction of heat shock proteins 70 and 27 and heat shock factor-1. Pancreas. 21:248–56.
-
(2000)
Pancreas
, vol.21
, pp. 248-256
-
-
Ethridge, R.T.1
-
125
-
-
77957239325
-
Alteration and role of heat shock proteins in acute pancreatitis
-
Feng JY, Li YY. (2010) Alteration and role of heat shock proteins in acute pancreatitis. J. Dig. Dis. 11:277–83.
-
(2010)
J. Dig. Dis
, vol.11
, pp. 277-283
-
-
Feng, J.Y.1
Li, Y.Y.2
-
126
-
-
0008949724
-
Water immersion stress induces heat shock protein 60 expression and protects against pancreatitis in rats
-
Lee HS, et al. (2000) Water immersion stress induces heat shock protein 60 expression and protects against pancreatitis in rats. Gastroenterology. 119:220–9.
-
(2000)
Gastroenterology
, vol.119
, pp. 220-229
-
-
Lee, H.S.1
-
127
-
-
3242720733
-
Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis
-
Kubisch C, et al. (2004) Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis. Gastroenterology. 127:275–86.
-
(2004)
Gastroenterology
, vol.127
, pp. 275-286
-
-
Kubisch, C.1
-
128
-
-
82955162458
-
Alteration in inflammatory/ apoptotic pathway and histone modifications by nordihydroguaiaretic acid prevents acute pancreatitis in Swiss albino mice
-
Mahajan UM, et al. (2011) Alteration in inflammatory/ apoptotic pathway and histone modifications by nordihydroguaiaretic acid prevents acute pancreatitis in Swiss albino mice. Apoptosis. 16:1138–49.
-
(2011)
Apoptosis
, vol.16
, pp. 1138-1149
-
-
Mahajan, U.M.1
-
129
-
-
81855216293
-
Heat shock proteins and autophagy in rats with cerulein-induced acute pancreatitis
-
Kim JN, et al. (2011) Heat shock proteins and autophagy in rats with cerulein-induced acute pancreatitis. Gut Liver. 5:513–20.
-
(2011)
Gut Liver
, vol.5
, pp. 513-520
-
-
Kim, J.N.1
-
130
-
-
51349155107
-
Extracellular heat-shock protein 70 aggravates cerulein-induced pancreatitis through toll-like receptor-4 in mice
-
Song JM, et al. (2008) Extracellular heat-shock protein 70 aggravates cerulein-induced pancreatitis through toll-like receptor-4 in mice. Chin. Med. J. (Engl). 121:1420–5.
-
(2008)
Chin. Med. J. (Engl)
, vol.121
, pp. 1420-1425
-
-
Song, J.M.1
-
131
-
-
66149096267
-
Serum heat shock protein 27 is increased in chronic pancreatitis and pancreatic carcinoma
-
Liao WC, et al. (2009) Serum heat shock protein 27 is increased in chronic pancreatitis and pancreatic carcinoma. Pancreas. 38:422–6.
-
(2009)
Pancreas
, vol.38
, pp. 422-426
-
-
Liao, W.C.1
-
134
-
-
79959842117
-
Evaluation of cell-free DNA in plasma and serum as early predictors of severity in acute pancreatitis
-
Gornik O, et al. (2011) Evaluation of cell-free DNA in plasma and serum as early predictors of severity in acute pancreatitis. Pancreas. 40:787–8.
-
(2011)
Pancreas
, vol.40
, pp. 787-788
-
-
Gornik, O.1
-
135
-
-
65649103076
-
Plasma concentrations of high-mobility group box protein 1, soluble receptor for advanced glycation end-products and circulating DNA in patients with acute pancreatitis
-
Kocsis AK, et al. (2009) Plasma concentrations of high-mobility group box protein 1, soluble receptor for advanced glycation end-products and circulating DNA in patients with acute pancreatitis. Pancreatology. 9:383–91.
-
(2009)
Pancreatology
, vol.9
, pp. 383-391
-
-
Kocsis, A.K.1
-
136
-
-
57649087470
-
Free serum DNA is an early predictor of severity in acute pancreatitis. Clin
-
Gornik I, et al. (2009) Free serum DNA is an early predictor of severity in acute pancreatitis. Clin. Biochem. 42:38–43.
-
(2009)
Biochem
, vol.42
, pp. 38-43
-
-
Gornik, I.1
-
137
-
-
33751084835
-
Quantitative analysis of plasma DNA in severe acute pancreatitis
-
Bagul A, et al. (2006) Quantitative analysis of plasma DNA in severe acute pancreatitis. JOP. 7:602–7.
-
(2006)
JOP
, vol.7
, pp. 602-607
-
-
Bagul, A.1
-
138
-
-
45549110399
-
Toll-like receptor 9 is expressed in rat pancreas and is involved in cerulein-induced pancreatitis
-
Zeng YJ, et al. (2008) Toll-like receptor 9 is expressed in rat pancreas and is involved in cerulein-induced pancreatitis. Pancreas. 36:212–4.
-
(2008)
Pancreas
, vol.36
, pp. 212-214
-
-
Zeng, Y.J.1
-
139
-
-
34247236200
-
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat
-
Tian J, et al. (2007) Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat. Immunol. 8:487–96.
-
(2007)
Immunol
, vol.8
, pp. 487-496
-
-
Tian, J.1
-
140
-
-
84862841848
-
Mitochondrial transcription factor A serves as a danger signal by augmenting plasmacytoid dendritic cell responses to DNA. J
-
Julian MW, et al. (2012) Mitochondrial transcription factor A serves as a danger signal by augmenting plasmacytoid dendritic cell responses to DNA. J. Immunol. 189:433–43.
-
(2012)
Immunol
, vol.189
, pp. 433-443
-
-
Julian, M.W.1
-
141
-
-
78650341420
-
The 1.5 A crystal structure of human receptor for advanced glycation endproducts (rage) ectodomains reveals unique features determining ligand binding
-
Park H, Boyington JC. (2010) The 1.5 A crystal structure of human receptor for advanced glycation endproducts (rage) ectodomains reveals unique features determining ligand binding. J. Biol. Chem. 285:40762-70.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 40762-40770
-
-
Park, H.1
Boyington, J.C.2
-
142
-
-
59649126956
-
Induction of inflammatory and immune responses by HMGB1- nucleosome complexes: Implications for the pathogenesis of SLE
-
Urbonaviciute V, et al. (2008) Induction of inflammatory and immune responses by HMGB1- nucleosome complexes: implications for the pathogenesis of SLE. J. Exp. Med. 205:3007–18.
-
(2008)
J. Exp. Med
, vol.205
, pp. 3007-3018
-
-
Urbonaviciute, V.1
-
144
-
-
70449107044
-
Extracellular histones are major mediators of death in sepsis
-
Xu J, et al. (2009) Extracellular histones are major mediators of death in sepsis. Nat. Med. 15:1318–21.
-
(2009)
Nat. Med
, vol.15
, pp. 1318-1321
-
-
Xu, J.1
-
145
-
-
80051882006
-
Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury
-
Xu J, et al. (2011) Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury. J. Immunol. 187:2626–31.
-
(2011)
J. Immunol
, vol.187
, pp. 2626-2631
-
-
Xu, J.1
-
146
-
-
0037023680
-
Apoptotic release of histones from nucleosomes
-
Wu D, et al. (2002) Apoptotic release of histones from nucleosomes. J. Biol. Chem. 277:12001–8.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 12001-12008
-
-
Wu, D.1
-
147
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
Brinkmann V, et al. (2004) Neutrophil extracellular traps kill bacteria. Science. 303:1532–5.
-
(2004)
Science
, vol.303
, pp. 1532-1535
-
-
Brinkmann, V.1
-
148
-
-
84896844884
-
Histones trigger sterile inflammation by activating the NLRP3 inflammasome. Eur. J
-
Allam R, Darisipudi MN, Tschopp J, Anders HJ. (2013) Histones trigger sterile inflammation by activating the NLRP3 inflammasome. Eur. J. Immunol. 43:3336–42.
-
(2013)
Immunol
, vol.43
, pp. 3336-3342
-
-
Allam, R.1
Darisipudi, M.N.2
Tschopp, J.3
Anders, H.J.4
-
151
-
-
0022629214
-
Extracellular ATP: Effects, sources and fate
-
Gordon JL. (1986) Extracellular ATP: effects, sources and fate. Biochem. J. 233:309–19.
-
(1986)
Biochem. J
, vol.233
, pp. 309-319
-
-
Gordon, J.L.1
-
152
-
-
0029665112
-
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
-
Surprenant A, et al. (1996) The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science. 272:735–8.
-
(1996)
Science
, vol.272
, pp. 735-738
-
-
Surprenant, A.1
-
153
-
-
77957942834
-
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
-
Chekeni FB, et al. (2010) Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis. Nature. 467:863–7.
-
(2010)
Nature
, vol.467
, pp. 863-867
-
-
Chekeni, F.B.1
-
154
-
-
0028030797
-
A new class of ligandgated ion channel defined by P2x receptor for extracellular ATP
-
Valera S, et al. (1994) A new class of ligandgated ion channel defined by P2x receptor for extracellular ATP. Nature. 371:516–9.
-
(1994)
Nature
, vol.371
, pp. 516-519
-
-
Valera, S.1
-
155
-
-
77950903448
-
Initiation of purinergic signaling by exocytosis of ATP-containing vesicles in liver epithelium
-
Feranchak AP, et al. (2010) Initiation of purinergic signaling by exocytosis of ATP-containing vesicles in liver epithelium. J. Biol. Chem. 285:8138–47.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 8138-8147
-
-
Feranchak, A.P.1
-
156
-
-
84870858655
-
ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner
-
Fader CM, Aguilera MO, Colombo MI. (2012) ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner. Autophagy. 8:1741-56.
-
(2012)
Autophagy
, vol.8
, pp. 1741-1756
-
-
Fader, C.M.1
Aguilera, M.O.2
Colombo, M.I.3
-
157
-
-
33644872533
-
Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis
-
Criddle DN, et al. (2006) Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis. Gastroenterology. 130:781–93.
-
(2006)
Gastroenterology
, vol.130
, pp. 781-793
-
-
Criddle, D.N.1
-
158
-
-
32544448639
-
P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. J
-
Suadicani SO, Brosnan CF, Scemes E. (2006) P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. J. Neurosci. 26:1378–85.
-
(2006)
Neurosci
, vol.26
, pp. 1378-1385
-
-
Suadicani, S.O.1
Brosnan, C.F.2
Scemes, E.3
-
159
-
-
84860419175
-
TLR4 but not TLR2 regulates inflammation and tissue damage in acute pancreatitis induced by retrograde infusion of taurocholate
-
Awla D, Abdulla A, Regner S, Thorlacius H. (2011) TLR4 but not TLR2 regulates inflammation and tissue damage in acute pancreatitis induced by retrograde infusion of taurocholate. Inflamm. Res. 60:1093–8.
-
(2011)
Inflamm. Res
, vol.60
, pp. 1093-1098
-
-
Awla, D.1
Abdulla, A.2
Regner, S.3
Thorlacius, H.4
-
160
-
-
66649119723
-
Impact of toll-like receptor 4 on the severity of acute pancreatitis and pancreatitis-associated lung injury in mice
-
Sharif R, et al. (2009) Impact of toll-like receptor 4 on the severity of acute pancreatitis and pancreatitis-associated lung injury in mice. Gut. 58:813–9.
-
(2009)
Gut
, vol.58
, pp. 813-819
-
-
Sharif, R.1
-
161
-
-
3943051390
-
Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia
-
Pastor CM, et al. (2004) Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia. Crit. Care Med. 32:1759–63.
-
(2004)
Crit. Care Med
, vol.32
, pp. 1759-1763
-
-
Pastor, C.M.1
-
162
-
-
84904489275
-
PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis
-
Yang L, et al. (2014) PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis. Nat. Commun. 2014;5:4436.
-
(2014)
Nat. Commun. 2014
, vol.5
, pp. 4436
-
-
Yang, L.1
|