Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells

Gastroenterology

Volumn 140, Issue 7, 2011, Pages 2116-2125

  Booth, David M ^a,b   Murphy, John A ^a,b   Mukherjee, Rajarshi ^a,b   Awais, Muhammad ^b   Neoptolemos, John P ^b   Gerasimenko, Oleg V ^c   Tepikin, Alexei V ^a   Petersen, Ole H ^c   Sutton, Robert ^b   Criddle, David N ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Caspase Activation; Free Radicals; NQO1; Pancreas

Indexed keywords

2 METHYLNAPHTHALENE; 2,4 DIMETHOXY 2 METHYLNAPHTHALENE; ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; BILE ACID; CALCIUM ION; MENADIONE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE QUININE OXIDOREDUCTASE; TAUROLITHOCHOLIC ACID; UNCLASSIFIED DRUG;

ACINAR CELL; ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DAMAGE; CELL DEATH; CELL ISOLATION; CELL PROTECTION; CHLORIDE CURRENT; CLINICAL TRIAL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NONHUMAN; PANCREATITIS; PATCH CLAMP; PRIORITY JOURNAL; WHOLE CELL;

EID: 79958157501     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.02.054     Document Type: Article

References (40)

1. S.J. Pandol, A.K. Saluja, and C.W. Imrie Acute pancreatitis: bench to the bedside Gastroenterology 132 2007 1127 1151 (Pubitemid 46440879)
2. O.A. Mareninova, K.F. Sung, and P. Hong Cell death in pancreatitis: caspases protect from necrotizing pancreatitis J Biol Chem 281 2006 3370 3381 (Pubitemid 43845951)
3. P.K. Garg, K. Madan, and G.K. Pande Association of extent and infection of pancreatic necrosis with organ failure and death in acute necrotizing pancreatitis Clin Gastroenterol Hepatol 3 2005 159 166 (Pubitemid 40220311)
4. D.N. Criddle, J.V. Gerasimenko, and H.K. Baumgartner Calcium signalling and pancreatic cell death: apoptosis or necrosis? Cell Death Differ 14 2007 1285 1294 (Pubitemid 46965259)
5. R. Lthen, C. Niederau, and J.H. Grendell Intrapancreatic zymogen activation and levels of ATP and glutathione during caerulein pancreatitis in rats Am J Physiol 268 1995 G592 G604
6. H. Sanfey, G.B. Bulkley, and J.L. Cameron The role of oxygen-derived free radicals in the pathogenesis of acute pancreatitis Ann Surg 200 1984 405 413 (Pubitemid 14024588)
7. P.L. Rutledge, A.K. Saluja, and R.E. Powers Role of oxygen-derived free radicals in diet-induced hemorrhagic pancreatitis in mice Gastroenterology 93 1987 41 47 (Pubitemid 17084091)
8. P.S. Leung, and Y.C. Chan Role of oxidative stress in pancreatic inflammation Antioxid Redox Signal 11 2009 135 165
9. B.K. Park, J.B. Chung, and J.H. Lee Role of oxygen free radicals in patients with acute pancreatitis World J Gastroenterol 9 2003 2266 2269 (Pubitemid 37321457)
10. M. Verlaan, H.M. Roelofs, and A. van-Schaik Assessment of oxidative stress in chronic pancreatitis patients World J Gastroenterol 12 2006 5705 5710 (Pubitemid 44594048)
11. Y. Bai, J. Gao, and W. Zhang Meta-analysis: allopurinol in the prevention of postendoscopic retrograde cholangiopancreatography pancreatitis Aliment Pharmacol Ther 28 2008 557 564
12. P. Bhardwaj, P.K. Garg, and S.K. Maulik A randomized controlled trial of antioxidant supplementation for pain relief in patients with chronic pancreatitis Gastroenterology 136 2009 149 159
13. A.K. Siriwardena, J.M. Mason, and S. Balachandra Randomised, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis Gut 56 2007 1439 1444 (Pubitemid 47517841)
14. G. Perides, J.M. Laukkarinen, and G. Vassileva Biliary acute pancreatitis in mice is mediated by the G-protein-coupled cell surface bile acid receptor Gpbar1 Gastroenterology 138 2010 715 725
15. J.V. Gerasimenko, S.E. Flowerdew, and S.G. Voronina Bile acids induce Ca(2+) release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors J Biol Chem 281 2006 40154 40163 (Pubitemid 46041820)
16. J.Y. Kim, K.H. Kim, and J.A. Lee Transporter-mediated bile acid uptake causes Ca2+-dependent cell death in rat pancreatic acinar cells Gastroenterology 122 2002 1941 1953 (Pubitemid 34651437)
17. D.N. Criddle, S. Gillies, and H.K. Baumgartner-Wilson Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells J Biol Chem 281 2006 40485 40492 (Pubitemid 46041851)
18. D.N. Criddle, J. Murphy, and G. Fistetto Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis Gastroenterology 130 2006 781 793 (Pubitemid 43374528)
19. 2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells Gastroenterology 135 2008 632 641
20. P. Smolewski, J. Grabarek, and H.D. Halicka Assay of caspase activation in situ combined with probing plasma membrane integrity to detect three distinct stages of apoptosis J Immunol Methods 265 2002 111 121 (Pubitemid 34628807)
21. O.A. Mareninova, K. Hermann, and S.W. French Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis J Clin Invest 119 2009 3340 3355
22. L. Galluzzi, S.A. Aaronson, and J. Abrams Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes Cell Death Differ 16 2009 1093 1107
23. M.K. Park, R.B. Lomax, and A.V. Tepikin Local uncaging of caged Ca(2+) reveals distribution of Ca(2+)-activated Cl(-) channels in pancreatic acinar cells Proc Natl Acad Sci U S A 98 2001 10948 10953 (Pubitemid 32878724)
24. O.H. Petersen, and A.V. Tepikin Polarized calcium signaling in exocrine gland cells Annu Rev Physiol 70 2008 273 299 (Pubitemid 351738181)
25. J.H. Yu, J.W. Lim, and K.H. Kim NADPH oxidase and apoptosis in cerulein-stimulated pancreatic acinar AR42J cells Free Radic Biol Med 39 2005 590 602
26. J.H. Yu, K.H. Kim, and D.G. Kim Diphenyleneiodonium suppresses apoptosis in cerulein-stimulated pancreatic acinar cells Int J Biochem Cell Biol 39 2007 2063 2075 (Pubitemid 47376827)
27. H.K. Baumgartner, J.V. Gerasimenko, and C. Thorne Calcium elevation in mitochondria is the main Ca2+ requirement for mitochondrial permeability transition pore (mPTP) opening J Biol Chem 284 2009 20796 20803
28. D. Hashimoto, M. Ohmuraya, and M. Hirota Involvement of autophagy in trypsinogen activation within pancreatic acinar cells J Cell Biol 181 2008 1065 1072 (Pubitemid 351915482)
29. W. Drge Free radicals in the physiological control of cell function Physiol Rev 82 2002 47 95
30. R.S. Balaban, S. Nemoto, and T. Finkel Mitochondria, oxidants, and aging Cell 120 2005 483 495 (Pubitemid 40269763)
31. S. Orrenius, V. Gogvadze, and B. Zhivotovsky Mitochondrial oxidative stress: implications for cell death Annu Rev Pharmacol Toxicol 47 2007 143 183
32. I.V. Odinokova, K.F. Sung, and O.A. Mareninova Mechanisms regulating cytochrome c release in pancreatic mitochondria Gut 58 2009 431 442
33. K.S. Guice, K.T. Oldham, and M.G. Caty Neutrophil-dependent, oxygen-radical mediated lung injury associated with acute pancreatitis Ann Surg 210 1989 740 747 (Pubitemid 20012435)
34. N. Tsuji, N. Watanabe, and T. Okamoto Specific interaction of pancreatic elastase and leucocytes to produce oxygen radicals and its implication in pancreatitis Gut 35 1994 1659 1664 (Pubitemid 24339273)
35. A.S. Gukovskaya, E. Vaquero, and V. Zaninovic Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis Gastroenterology 122 2002 974 984 (Pubitemid 34267281)
36. E.P. Reeves, H. Lu, and H.L. Jacobs Killing activity of neutrophils is mediated through activation of proteases by K+ flux Nature 416 2002 291 297 (Pubitemid 34260237)
37. T.E. DeCoursey, D. Morgan, and V.V. Cherney The voltage dependence of NADPH oxidase reveals why phagocytes need proton channels Nature 422 2003 531 534 (Pubitemid 36433649)
38. J. Christophe Pancreatic tumoral cell line AR42J: an amphicrine model Am J Physiol 266 1994 G963 G971
39. H.R. Oliveira, R. Verlengia, and C.R. Carvalho Pancreatic beta-cells express phagocyte-like NAD(P)H oxidase Diabetes 52 2003 1457 1463 (Pubitemid 36666201)
40. G. Bjelakovic, D. Nikolova, and L.L. Gluud Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis JAMA 297 2007 842 857 (Pubitemid 46333949)