메뉴 건너뛰기




Volumn 9, Issue 4, 2013, Pages 451-458

DAMPs and autophagy: Cellular adaptation to injury and unscheduled cell death

Author keywords

ATP; Autophagy; DAMP; HMGB1; IL1B; Injury; Stress

Indexed keywords

ABC TRANSPORTER; ADAPTOR PROTEIN; ADENOSINE TRIPHOSPHATE; ADVANCED GLYCATION END PRODUCT; CALCIUM BINDING PROTEIN; CASPASE 8; CRYOPYRIN; DAMAGE ASSOCIATED MOLECULAR PATTERN MOLECULE; DEATH RECEPTOR; HEAT SHOCK PROTEIN; INFLAMMASOME; INTERLEUKIN 1; INTERLEUKIN 1BETA; MICROTUBULE ASSOCIATED PROTEIN 1; MITOCHONDRIAL DNA; PATTERN RECOGNITION RECEPTOR; PROTEIN; SYNAPTOBREVIN; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VESICLE ASSOCIATED MEMBRANE PROTEIN 7;

EID: 84877328234     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.23691     Document Type: Review
Times cited : (115)

References (92)
  • 1
    • 37349057040 scopus 로고    scopus 로고
    • The first systems biologist, and the future of physiology
    • PMID:17951329
    • Noble D. Claude Bernard, the first systems biologist, and the future of physiology. Exp Physiol 2008; 93:16-26; PMID:17951329; http://dx.doi.org/10. 1113/expphysiol. 2007.038695
    • (2008) Exp Physiol , vol.93 , pp. 16-26
    • Noble, D.1    Claude, B.2
  • 2
    • 77955965172 scopus 로고    scopus 로고
    • Cellular stress responses: Cell survival and cell death
    • PMID:20182529
    • Fulda S, Gorman AM, Hori O, Samali A. Cellular stress responses: Cell survival and cell death. Int J Cell Biol 2010; 2010:214074; PMID:20182529; http://dx.doi.org/10.1155/2010/214074
    • (2010) Int J Cell Biol , vol.2010 , pp. 214074
    • Fulda, S.1    Gorman, A.M.2    Hori, O.3    Samali, A.4
  • 3
    • 15544377794 scopus 로고    scopus 로고
    • Molecular and evolutionary basis of the cellular stress response
    • PMID:15709958
    • Kültz D. Molecular and evolutionary basis of the cellular stress response. Annu Rev Physiol 2005; 67:225-57; PMID:15709958; http://dx.doi.org/10. 1146/annurev. physiol.67.040403.103635
    • (2005) Annu Rev Physiol , vol.67 , pp. 225-257
    • Kültz, D.1
  • 4
    • 57649149333 scopus 로고    scopus 로고
    • Classification of cell death: Recommendations of the nomenclature committee on cell death 2009
    • Nomenclature Committee on Cell Death, PMID:18846107
    • Kroemer G, Galluzzi L, Vandenabeele P, Abrams J, Alnemri ES, Baehrecke EH, et al.; Nomenclature Committee on Cell Death 2009. Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 2009; 16:3-11; PMID:18846107; http://dx.doi.org/10.1038/cdd.2008. 150
    • (2009) Cell Death Differ , vol.2009 , pp. 163-1611
    • Kroemer, G.1    Galluzzi, L.2    Vandenabeele, P.3    Abrams, J.4    Alnemri, E.S.5    Baehrecke, E.H.6
  • 5
    • 84255210700 scopus 로고    scopus 로고
    • Molecular definitions of cell death subroutines: Recommendations of the nomenclature committee on cell death 2012
    • PMID:21760595
    • Galluzzi L, Vitale I, Abrams JM, Alnemri ES, Baehrecke EH, Blagosklonny MV, et al. Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 2012; 19:107-20; PMID:21760595; http://dx.doi.org/10.1038/cdd.2011.96
    • (2012) Cell Death Differ , vol.19 , pp. 107-120
    • Galluzzi, L.1    Vitale, I.2    Abrams, J.M.3    Alnemri, E.S.4    Baehrecke, E.H.5    Blagosklonny, M.V.6
  • 6
    • 84861541814 scopus 로고    scopus 로고
    • Ferroptosis: An iron-dependent form of nonapoptotic cell death
    • PMID:22632970
    • Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, et al. Ferroptosis: An iron-dependent form of nonapoptotic cell death. Cell 2012; 149:1060-72; PMID:22632970; http://dx.doi.org/10.1016/j.cell.2012.03.042
    • (2012) Cell , vol.149 , pp. 1060-1072
    • Dixon, S.J.1    Lemberg, K.M.2    Lamprecht, M.R.3    Skouta, R.4    Zaitsev, E.M.5    Gleason, C.E.6
  • 7
    • 38349194472 scopus 로고    scopus 로고
    • Cell death in health and disease
    • PMID:18031301
    • Lockshin RA, Zakeri Z. Cell death in health and disease. J Cell Mol Med 2007; 11:1214-24; PMID:18031301; http://dx.doi.org/10.1111/j.1582-4934.2007. 00150.x
    • (2007) J Cell Mol Med , vol.11 , pp. 1214-1224
    • Lockshin, R.A.1    Zakeri, Z.2
  • 8
    • 79952811804 scopus 로고    scopus 로고
    • RIP3 mediates the embryonic lethality of caspase-8-deficient mice
    • PMID 21368762
    • Kaiser WJ, Upton JW, Long AB, Livingston-Rosanoff D, Daley-Bauer LP, Hakem R, et al. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 2011; 471:368-72; PMID:21368762; http://dx.doi.org/10.1038/ nature09857
    • (2011) Nature , vol.471 , pp. 368-372
    • Kaiser, W.J.1    Upton, J.W.2    Long, A.B.3    Livingston-Rosanoff, D.4    Daley-Bauer, L.P.5    Hakem, R.6
  • 9
    • 80054888589 scopus 로고    scopus 로고
    • It cuts both ways: Reconciling the dual roles of caspase 8 in cell death and survival
    • PMID:22016059
    • Oberst A, Green DR. It cuts both ways: Reconciling the dual roles of caspase 8 in cell death and survival. Nat Rev Mol Cell Biol 2011; 12:757-63; PMID:22016059; http://dx.doi.org/10.1038/nrm3214
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 757-763
    • Oberst, A.1    Green, D.R.2
  • 10
    • 84861712290 scopus 로고    scopus 로고
    • Survival function of the FADDCASPASE-8-cFLIP(L) complex
    • PMID:22675671
    • Dillon CP, Oberst A, Weinlich R, Janke LJ, Kang TB, Ben-Moshe T, et al. Survival function of the FADDCASPASE-8-cFLIP(L) complex. Cell Rep 2012; 1:401-7; PMID:22675671; http://dx.doi.org/10.1016/j.celrep. 2012.03.010
    • (2012) Cell Rep , vol.1 , pp. 401-407
    • Dillon, C.P.1    Oberst, A.2    Weinlich, R.3    Janke, L.J.4    Kang, T.B.5    Ben-Moshe, T.6
  • 11
    • 79955485120 scopus 로고    scopus 로고
    • Apoptosis promotes early tumorigenesis
    • PMID:21151175
    • Tang D, Lotze MT, Kang R, Zeh HJ. Apoptosis promotes early tumorigenesis. Oncogene 2011; 30:1851-4; PMID:21151175; http://dx.doi.org/10.1038/onc.2010.573
    • (2011) Oncogene , vol.30 , pp. 1851-1854
    • Tang, D.1    Lotze, M.T.2    Kang, R.3    Zeh, H.J.4
  • 12
    • 5944251623 scopus 로고    scopus 로고
    • Caspase inhibitors improve survival in sepsis: A critical role of the lymphocyte
    • PMID:11101871
    • Hotchkiss RS, Chang KC, Swanson PE, Tinsley KW, Hui JJ, Klender P, et al. Caspase inhibitors improve survival in sepsis: A critical role of the lymphocyte. Nat Immunol 2000; 1:496-501; PMID:11101871; http://dx.doi.org/10. 1038/82741
    • (2000) Nat Immunol , vol.1 , pp. 496-501
    • Hotchkiss, R.S.1    Chang, K.C.2    Swanson, P.E.3    Tinsley, K.W.4    Hui, J.J.5    Klender, P.6
  • 13
    • 33745854493 scopus 로고    scopus 로고
    • Role of HMGB1 in apoptosis-mediated sepsis lethality
    • PMID:16818669
    • Qin S, Wang H, Yuan R, Li H, Ochani M, Ochani K, et al. Role of HMGB1 in apoptosis-mediated sepsis lethality. J Exp Med 2006; 203:1637-42; PMID:16818669; http://dx.doi.org/10.1084/jem.20052203
    • (2006) J Exp Med , vol.203 , pp. 1637-1642
    • Qin, S.1    Wang, H.2    Yuan, R.3    Li, H.4    Ochani, M.5    Ochani, K.6
  • 14
    • 77956404377 scopus 로고    scopus 로고
    • Eaten alive: A history of macroautophagy
    • PMID:20811353
    • Yang Z, Klionsky DJ. Eaten alive: A history of macroautophagy. Nat Cell Biol 2010; 12:814-22; PMID:20811353; http://dx.doi.org/10.1038/ncb0910-814
    • (2010) Nat Cell Biol , vol.12 , pp. 814-822
    • Yang, Z.1    Klionsky, D.J.2
  • 15
    • 80054025654 scopus 로고    scopus 로고
    • The role of Atg proteins in autophagosome formation
    • PMID:21801009
    • Mizushima N, Yoshimori T, Ohsumi Y. The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol 2011; 27:107-32; PMID:21801009; http://dx.doi.org/10.1146/annurev-cellbio-092910-154005
    • (2011) Annu Rev Cell Dev Biol , vol.27 , pp. 107-132
    • Mizushima, N.1    Yoshimori, T.2    Ohsumi, Y.3
  • 16
    • 77956414236 scopus 로고    scopus 로고
    • The origin of the autophagosomal membrane
    • PMID:20811355
    • Tooze SA, Yoshimori T. The origin of the autophagosomal membrane. Nat Cell Biol 2010; 12:831-5; PMID:20811355; http://dx.doi.org/10.1038/ncb0910-831
    • (2010) Nat Cell Biol , vol.12 , pp. 831-835
    • Tooze, S.A.1    Yoshimori, T.2
  • 17
    • 78650467974 scopus 로고    scopus 로고
    • Mechanisms of mitophagy
    • PMID:21179058
    • Youle RJ, Narendra DP. Mechanisms of mitophagy. Nat Rev Mol Cell Biol 2011; 12:9-14; PMID:21179058; http://dx.doi.org/10.1038/nrm3028
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 9-14
    • Youle, R.J.1    Narendra, D.P.2
  • 18
    • 12944308330 scopus 로고    scopus 로고
    • Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense
    • PMID:15680321
    • Levine B. Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense. Cell 2005; 120:159-62; PMID:15680321
    • (2005) Cell , vol.120 , pp. 159-162
    • Levine, B.1
  • 19
    • 84872466790 scopus 로고    scopus 로고
    • Eat-Me: Autophagy, phagocytosis, and reactive oxygen species signaling
    • PMID:22871044
    • Vernon PJ, Tang D. Eat-Me: Autophagy, Phagocytosis, and Reactive Oxygen Species Signaling. Antioxid Redox Signal 2013; 18:677-91; PMID:22871044; http://dx.doi.org/10.1089/ars.2012.4810
    • (2013) Antioxid Redox Signal , vol.18 , pp. 677-691
    • Vernon, P.J.1    Tang, D.2
  • 20
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • PMID:21311563
    • Kang R, Zeh HJ, Lotze MT, Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 2011; 18:571-80; PMID:21311563; http://dx.doi.org/10.1038/cdd.2010.191
    • (2011) Cell Death Differ , vol.18 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 21
    • 25144506835 scopus 로고    scopus 로고
    • Autophagy in cell death: An innocent convict?
    • PMID:16200202
    • Levine B, Yuan J. Autophagy in cell death: An innocent convict? J Clin Invest 2005; 115:2679-88; PMID:16200202; http://dx.doi.org/10.1172/JCI26390
    • (2005) J Clin Invest , vol.115 , pp. 2679-2688
    • Levine, B.1    Yuan, J.2
  • 22
    • 56749170677 scopus 로고    scopus 로고
    • Autophagic cell death: The story of a misnomer
    • PMID:18971948
    • Kroemer G, Levine B. Autophagic cell death: The story of a misnomer. Nat Rev Mol Cell Biol 2008; 9:1004-10; PMID:18971948; http://dx.doi.org/10.1038/ nrm2529
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 1004-1010
    • Kroemer, G.1    Levine, B.2
  • 23
    • 77956416339 scopus 로고    scopus 로고
    • Autophagy in mammalian development and differentiation
    • PMID:20811354
    • Mizushima N, Levine B. Autophagy in mammalian development and differentiation. Nat Cell Biol 2010; 12:823-30; PMID:20811354; http://dx.doi.org/10.1038/ncb0910-823
    • (2010) Nat Cell Biol , vol.12 , pp. 823-830
    • Mizushima, N.1    Levine, B.2
  • 24
    • 34548188741 scopus 로고    scopus 로고
    • Selfeating and self-killing: Crosstalk between autophagy and apoptosis
    • PMID:17717517
    • Maiuri MC, Zalckvar E, Kimchi A, Kroemer G. Selfeating and self-killing: Crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 2007; 8:741-52; PMID:17717517; http://dx.doi.org/10.1038/nrm2239
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 25
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • PMID:21248839
    • Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature 2011; 469:323-35; PMID:21248839; http://dx.doi.org/10.1038/nature09782
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 26
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • PMID:18191218
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132:27-42; PMID:18191218; http://dx.doi.org/10.1016/j.cell.2007.12.018
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 27
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • PMID:18305538
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008; 451:1069-75; PMID:18305538; http://dx.doi.org/10.1038/nature06639
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 28
    • 78649704325 scopus 로고    scopus 로고
    • Autophagy and metabolism
    • PMID:21127245
    • Rabinowitz JD, White E. Autophagy and metabolism. Science 2010; 330:1344-8; PMID:21127245; http://dx.doi.org/10.1126/science.1193497
    • (2010) Science , vol.330 , pp. 1344-1348
    • Rabinowitz, J.D.1    White, E.2
  • 29
    • 67649607465 scopus 로고    scopus 로고
    • Autophagy, immunity, and microbial adaptations
    • PMID:19527881
    • Deretic V, Levine B. Autophagy, immunity, and microbial adaptations. Cell Host Microbe 2009; 5:527-49; PMID:19527881; http://dx.doi.org/10.1016/j.chom. 2009.05.016
    • (2009) Cell Host Microbe , vol.5 , pp. 527-549
    • Deretic, V.1    Levine, B.2
  • 30
    • 34548700796 scopus 로고    scopus 로고
    • Unveiling the roles of autophagy in innate and adaptive immunity
    • PMID:17767194
    • Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol 2007; 7:767-77; PMID:17767194; http://dx.doi.org/10.1038/nri2161
    • (2007) Nat Rev Immunol , vol.7 , pp. 767-777
    • Levine, B.1    Deretic, V.2
  • 31
    • 84862295360 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy
    • PMID:22966490
    • Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012; 8:445-544; PMID:22966490; http://dx.doi.org/10.4161/auto.19496
    • (2012) Autophagy , vol.8 , pp. 445-544
    • Klionsky, D.J.1    Abdalla, F.C.2    Abeliovich, H.3    Abraham, R.T.4    Acevedo-Arozena, A.5    Adeli, K.6
  • 32
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • PMID:20144757
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 2010; 140:313-26; PMID:20144757; http://dx.doi.org/10.1016/j. cell.2010.01.028
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 33
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • PMID:2700931
    • Janeway CA Jr. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol 1989; 54:1-13; PMID:2700931; http://dx.doi.org/10.1101/SQB.1989.054.01.003
    • (1989) Cold Spring Harb Symp Quant Biol , vol.54 , pp. 1-13
    • Janeway Jr., C.A.1
  • 34
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • PMID:8011301
    • Matzinger P. Tolerance, danger, and the extended family. Annu Rev Immunol 1994; 12:991-1045; PMID:8011301; http://dx.doi.org/10.1146/annurev. iy.12.040194.005015
    • (1994) Annu Rev Immunol , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 35
    • 2942627626 scopus 로고    scopus 로고
    • Hydrophobicity: An ancient damage-associated molecular pattern that initiates innate immune responses
    • PMID:15173835
    • Seong SY, Matzinger P. Hydrophobicity: An ancient damage-associated molecular pattern that initiates innate immune responses. Nat Rev Immunol 2004; 4:469-78; PMID:15173835; http://dx.doi.org/10.1038/nri1372
    • (2004) Nat Rev Immunol , vol.4 , pp. 469-478
    • Seong, S.Y.1    Matzinger, P.2
  • 36
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs PAMPs and alarmins: All we need to know about danger
    • PMID:17032697
    • Bianchi ME. DAMPs, PAMPs and alarmins: All we need to know about danger. J Leukoc Biol 2007; 81:1-5; PMID:17032697; http://dx.doi.org/10.1189/jlb.0306164
    • (2007) J Leukoc Biol , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 37
    • 79953068336 scopus 로고    scopus 로고
    • Emerging role of damageassociated molecular patterns derived from mitochondria in inflammation
    • PMID:21334975
    • Krysko DV, Agostinis P, Krysko O, Garg AD, Bachert C, Lambrecht BN, et al. Emerging role of damageassociated molecular patterns derived from mitochondria in inflammation. Trends Immunol 2011; 32:157-64; PMID:21334975; http://dx.doi.org/10.1016/j.it.2011.01.005
    • (2011) Trends Immunol , vol.32 , pp. 157-164
    • Krysko, D.V.1    Agostinis, P.2    Krysko, O.3    Garg, A.D.4    Bachert, C.5    Lambrecht, B.N.6
  • 38
    • 84865299726 scopus 로고    scopus 로고
    • PAMPs and DAMPs: Signal 0s that spur autophagy and immunity
    • PMID:22889221
    • Tang D, Kang R, Coyne CB, Zeh HJ, Lotze MT. PAMPs and DAMPs: Signal 0s that spur autophagy and immunity. Immunol Rev 2012; 249:158-75; PMID:22889221; http://dx.doi.org/10.1111/j.1600-065X.2012.01146.x
    • (2012) Immunol Rev , vol.249 , pp. 158-175
    • Tang, D.1    Kang, R.2    Coyne, C.B.3    Zeh, H.J.4    Lotze, M.T.5
  • 39
    • 79953066407 scopus 로고    scopus 로고
    • HMGB1 is a therapeutic target for sterile inflammation and infection
    • PMID:21219181
    • Andersson U, Tracey KJ. HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol 2011; 29:139-62; PMID:21219181; http://dx.doi.org/10.1146/annurev-immunol-030409-101323
    • (2011) Annu Rev Immunol , vol.29 , pp. 139-162
    • Andersson, U.1    Tracey, K.J.2
  • 40
    • 0036775236 scopus 로고    scopus 로고
    • The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesiclemediated secretory pathway
    • PMID:12231511
    • Gardella S, Andrei C, Ferrera D, Lotti LV, Torrisi MR, Bianchi ME, et al. The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesiclemediated secretory pathway. EMBO Rep 2002; 3:995-1001; PMID:12231511; http://dx.doi.org/10.1093/embo-reports/kvf198
    • (2002) EMBO Rep , vol.3 , pp. 995-1001
    • Gardella, S.1    Andrei, C.2    Ferrera, D.3    Lotti, L.V.4    Torrisi, M.R.5    Bianchi, M.E.6
  • 41
    • 68649102975 scopus 로고    scopus 로고
    • Mechanisms of interleukin-1beta release
    • PMID:19250700
    • Eder C. Mechanisms of interleukin-1beta release. Immunobiology 2009; 214:543-53; PMID:19250700; http://dx.doi.org/10.1016/j.imbio.2008.11.007
    • (2009) Immunobiology , vol.214 , pp. 543-553
    • Eder, C.1
  • 42
    • 0038701886 scopus 로고    scopus 로고
    • The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes
    • PMID:12752430
    • Nickel W. The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes. Eur J Biochem 2003; 270:2109-19; PMID:12752430; http://dx.doi.org/10.1046/j.1432-1033.2003.03577.x
    • (2003) Eur J Biochem , vol.270 , pp. 2109-2119
    • Nickel, W.1
  • 43
    • 58849089529 scopus 로고    scopus 로고
    • Mechanisms of regulated unconventional protein secretion
    • PMID:19122676
    • Nickel W, Rabouille C. Mechanisms of regulated unconventional protein secretion. Nat Rev Mol Cell Biol 2009; 10:148-55; PMID:19122676; http://dx.doi.org/10.1038/nrm2617
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 148-155
    • Nickel, W.1    Rabouille, C.2
  • 44
    • 84864295258 scopus 로고    scopus 로고
    • Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation
    • PMID:22677446
    • Deretic V, Jiang S, Dupont N. Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation. Trends Cell Biol 2012; 22:397-406; PMID:22677446; http://dx.doi.org/10.1016/j. tcb.2012.04.008
    • (2012) Trends Cell Biol , vol.22 , pp. 397-406
    • Deretic, V.1    Jiang, S.2    Dupont, N.3
  • 45
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
    • PMID:15803152
    • Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal. Nat Rev Immunol 2005; 5:331-42; PMID:15803152; http://dx.doi.org/10.1038/nri1594
    • (2005) Nat Rev Immunol , vol.5 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 46
    • 77956386515 scopus 로고    scopus 로고
    • Endogenous HMGB1 regulates autophagy
    • PMID:20819940
    • Tang D, Kang R, Livesey KM, Cheh CW, Farkas A, Loughran P, et al. Endogenous HMGB1 regulates autophagy. J Cell Biol 2010; 190:881-92; PMID:20819940; http://dx.doi.org/10.1083/jcb.200911078
    • (2010) J Cell Biol , vol.190 , pp. 881-892
    • Tang, D.1    Kang, R.2    Livesey, K.M.3    Cheh, C.W.4    Farkas, A.5    Loughran, P.6
  • 47
    • 80052589806 scopus 로고    scopus 로고
    • High mobility group box 1 (HMGB1) activates an autophagic response to oxidative stress
    • PMID:21395369
    • Tang D, Kang R, Livesey KM, Zeh HJ 3rd, Lotze MT. High mobility group box 1 (HMGB1) activates an autophagic response to oxidative stress. Antioxid Redox Signal 2011; 15:2185-95; PMID:21395369; http://dx.doi.org/10.1089/ars.2010.3666
    • (2011) Antioxid Redox Signal , vol.15 , pp. 2185-2195
    • Tang, D.1    Kang, R.2    Livesey, K.M.3    Zeh III, H.J.4    Lotze, M.T.5
  • 48
    • 82455210868 scopus 로고    scopus 로고
    • Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
    • PMID:22068051
    • Dupont N, Jiang S, Pilli M, Ornatowski W, Bhattacharya D, Deretic V. Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β. EMBO J 2011; 30:4701-11; PMID:22068051; http://dx.doi.org/10.1038/ emboj.2011.398
    • (2011) EMBO J , vol.30 , pp. 4701-4711
    • Dupont, N.1    Jiang, S.2    Pilli, M.3    Ornatowski, W.4    Bhattacharya, D.5    Deretic, V.6
  • 49
    • 57649217868 scopus 로고    scopus 로고
    • Autophagy regulates selective HMGB1 release in tumor cells that are destined to die
    • PMID:18846108
    • Thorburn J, Horita H, Redzic J, Hansen K, Frankel AE, Thorburn A. Autophagy regulates selective HMGB1 release in tumor cells that are destined to die. Cell Death Differ 2009; 16:175-83; PMID:18846108; http://dx.doi.org/10. 1038/cdd.2008.143
    • (2009) Cell Death Differ , vol.16 , pp. 175-183
    • Thorburn, J.1    Horita, H.2    Redzic, J.3    Hansen, K.4    Frankel, A.E.5    Thorburn, A.6
  • 50
    • 84866554641 scopus 로고    scopus 로고
    • Autophagy mediates the delivery of thrombogenic tissue factor to neutrophil extracellular traps in human sepsis
    • PMID:23029002
    • Kambas K, Mitroulis I, Apostolidou E, Girod A, Chrysanthopoulou A, Pneumatikos I, et al. Autophagy mediates the delivery of thrombogenic tissue factor to neutrophil extracellular traps in human sepsis. PLoS One 2012; 7:e45427; PMID:23029002; http://dx.doi.org/10.1371/journal.pone.0045427
    • (2012) PLoS One , vol.7
    • Kambas, K.1    Mitroulis, I.2    Apostolidou, E.3    Girod, A.4    Chrysanthopoulou, A.5    Pneumatikos, I.6
  • 51
    • 83455182149 scopus 로고    scopus 로고
    • Neutrophil extracellular trap formation is associated with IL-1β and autophagy-related signaling in gout
    • PMID:22195044
    • Mitroulis I, Kambas K, Chrysanthopoulou A, Skendros P, Apostolidou E, Kourtzelis I, et al. Neutrophil extracellular trap formation is associated with IL-1β and autophagy-related signaling in gout. PLoS One 2011; 6:e29318; PMID:22195044; http://dx.doi.org/10.1371/journal.pone.0029318.
    • (2011) PLoS One , vol.6
    • Mitroulis, I.1    Kambas, K.2    Chrysanthopoulou, A.3    Skendros, P.4    Apostolidou, E.5    Kourtzelis, I.6
  • 52
    • 84868503604 scopus 로고    scopus 로고
    • Tanshinone IIA sodium sulfonate facilitates endocytic HMGB1 uptake
    • PMID:23022229
    • Zhang Y, Li W, Zhu S, Jundoria A, Li J, Yang H, et al. Tanshinone IIA sodium sulfonate facilitates endocytic HMGB1 uptake. Biochem Pharmacol 2012; 84:1492-500; PMID:23022229; http://dx.doi.org/10.1016/j.bcp.2012.09.015
    • (2012) Biochem Pharmacol , vol.84 , pp. 1492-1500
    • Zhang, Y.1    Li, W.2    Zhu, S.3    Jundoria, A.4    Li, J.5    Yang, H.6
  • 53
    • 79953685881 scopus 로고    scopus 로고
    • EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages
    • PMID:21371444
    • Li W, Zhu S, Li J, Assa A, Jundoria A, Xu J, et al. EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages. Biochem Pharmacol 2011; 81:1152-63; PMID:21371444; http://dx.doi.org/10.1016/j.bcp.2011.02.015
    • (2011) Biochem Pharmacol , vol.81 , pp. 1152-1163
    • Li, W.1    Zhu, S.2    Li, J.3    Assa, A.4    Jundoria, A.5    Xu, J.6
  • 54
    • 62349114041 scopus 로고    scopus 로고
    • Extracellular ATP in the immune system: More than just a "danger signal"
    • PMID:19193605
    • Trautmann A. Extracellular ATP in the immune system: More than just a "danger signal". Sci Signal 2009; 2:pe6; PMID:19193605; http://dx.doi.org/10.1126/scisignal.256pe6
    • (2009) Sci Signal , vol.2
    • Trautmann, A.1
  • 55
    • 84863103053 scopus 로고    scopus 로고
    • ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages
    • PMID:22768222
    • Ayna G, Krysko DV, Kaczmarek A, Petrovski G, Vandenabeele P, Fésüs L. ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages. PLoS One 2012; 7:e40069; PMID:22768222; http://dx.doi.org/10.1371/journal.pone.0040069
    • (2012) PLoS One , vol.7
    • Ayna, G.1    Krysko, D.V.2    Kaczmarek, A.3    Petrovski, G.4    Vandenabeele, P.5    Fésüs, L.6
  • 56
    • 83755181759 scopus 로고    scopus 로고
    • Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice
    • PMID:22174255
    • Michaud M, Martins I, Sukkurwala AQ, Adjemian S, Ma Y, Pellegatti P, et al. Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice. Science 2011; 334:1573-7; PMID:22174255; http://dx.doi.org/10. 1126/science. 1208347
    • (2011) Science , vol.334 , pp. 1573-1577
    • Michaud, M.1    Martins, I.2    Sukkurwala, A.Q.3    Adjemian, S.4    Ma, Y.5    Pellegatti, P.6
  • 57
    • 84870858655 scopus 로고    scopus 로고
    • ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner
    • PMID:22951367
    • Fader CM, Aguilera MO, Colombo MI. ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner. Autophagy 2012; 8:1741-56; PMID:22951367; http://dx.doi.org/10.4161/auto.21858
    • (2012) Autophagy , vol.8 , pp. 1741-1756
    • Fader, C.M.1    Aguilera, M.O.2    Colombo, M.I.3
  • 58
    • 79960798816 scopus 로고    scopus 로고
    • SNARE proteins are required for macroautophagy
    • PMID:21784249
    • Nair U, Jotwani A, Geng J, Gammoh N, Richerson D, Yen WL, et al. SNARE proteins are required for macroautophagy. Cell 2011; 146:290-302; PMID:21784249; http://dx.doi.org/10.1016/j.cell.2011.06.022
    • (2011) Cell , vol.146 , pp. 290-302
    • Nair, U.1    Jotwani, A.2    Geng, J.3    Gammoh, N.4    Richerson, D.5    Yen, W.L.6
  • 59
    • 79960774898 scopus 로고    scopus 로고
    • Autophagosome precursor maturation requires homotypic fusion
    • PMID:21784250
    • Moreau K, Ravikumar B, Renna M, Puri C, Rubinsztein DC. Autophagosome precursor maturation requires homotypic fusion. Cell 2011; 146:303-17; PMID:21784250; http://dx.doi.org/10.1016/j.cell.2011.06.023
    • (2011) Cell , vol.146 , pp. 303-317
    • Moreau, K.1    Ravikumar, B.2    Renna, M.3    Puri, C.4    Rubinsztein, D.C.5
  • 60
    • 84870880174 scopus 로고    scopus 로고
    • The hairpintype tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes
    • PMID:23217709
    • Itakura E, Kishi-Itakura C, Mizushima N. The hairpintype tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell 2012; 151:1256-69; PMID:23217709; http://dx.doi.org/10.1016/j.cell.2012. 11.001
    • (2012) Cell , vol.151 , pp. 1256-1269
    • Itakura, E.1    Kishi-Itakura, C.2    Mizushima, N.3
  • 61
    • 56249090667 scopus 로고    scopus 로고
    • Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
    • PMID:18849965
    • Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 2008; 456:264-8; PMID:18849965; http://dx.doi.org/10.1038/nature07383
    • (2008) Nature , vol.456 , pp. 264-268
    • Saitoh, T.1    Fujita, N.2    Jang, M.H.3    Uematsu, S.4    Yang, B.G.5    Satoh, T.6
  • 62
    • 79953176280 scopus 로고    scopus 로고
    • Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation
    • PMID:21228274
    • Harris J, Hartman M, Roche C, Zeng SG, O'Shea A, Sharp FA, et al. Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation. J Biol Chem 2011; 286:9587-97; PMID:21228274; http://dx.doi.org/10.1074/jbc. M110.202911.
    • (2011) J Biol Chem , vol.286 , pp. 9587-9597
    • Harris, J.1    Hartman, M.2    Roche, C.3    Zeng, S.G.4    O'Shea, A.5    Sharp, F.A.6
  • 63
    • 84863078686 scopus 로고    scopus 로고
    • Autophagy suppresses interleukin-1β (IL-1β) signaling by activation of p62 degradation via lysosomal and proteasomal pathways
    • PMID:22167182
    • Lee J, Kim HR, Quinley C, Kim J, Gonzalez-Navajas J, Xavier R, et al. Autophagy suppresses interleukin-1β (IL-1β) signaling by activation of p62 degradation via lysosomal and proteasomal pathways. J Biol Chem 2012; 287:4033-40; PMID:22167182; http://dx.doi.org/10.1074/jbc.M111.280065
    • (2012) J Biol Chem , vol.287 , pp. 4033-4040
    • Lee, J.1    Kim, H.R.2    Quinley, C.3    Kim, J.4    Gonzalez-Navajas, J.5    Xavier, R.6
  • 64
    • 84857195479 scopus 로고    scopus 로고
    • Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
    • PMID:22286270
    • Shi CS, Shenderov K, Huang NN, Kabat J, Abu-Asab M, Fitzgerald KA, et al. Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol 2012; 13:255-63; PMID:22286270; http://dx.doi.org/10.1038/ni.2215
    • (2012) Nat Immunol , vol.13 , pp. 255-263
    • Shi, C.S.1    Shenderov, K.2    Huang, N.N.3    Kabat, J.4    Abu-Asab, M.5    Fitzgerald, K.A.6
  • 65
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • PMID:21124315
    • Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011; 469:221-5; PMID:21124315; http://dx.doi.org/10.1038/nature09663
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4
  • 66
    • 80053303830 scopus 로고    scopus 로고
    • Autophagy and cytokines
    • PMID:21889357
    • Harris J. Autophagy and cytokines. Cytokine 2011; 56:140-4; PMID:21889357; http://dx.doi.org/10.1016/j.cyto.2011.08.022
    • (2011) Cytokine , vol.56 , pp. 140-144
    • Harris, J.1
  • 67
    • 37549043217 scopus 로고    scopus 로고
    • Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
    • PMID:18097414
    • Sanjuan MA, Dillon CP, Tait SW, Moshiach S, Dorsey F, Connell S, et al. Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature 2007; 450:1253-7; PMID:18097414; http://dx.doi.org/10.1038/ nature06421
    • (2007) Nature , vol.450 , pp. 1253-1257
    • Sanjuan, M.A.1    Dillon, C.P.2    Tait, S.W.3    Moshiach, S.4    Dorsey, F.5    Connell, S.6
  • 68
    • 80054825045 scopus 로고    scopus 로고
    • Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells
    • PMID:21969579
    • Martinez J, Almendinger J, Oberst A, Ness R, Dillon CP, Fitzgerald P, et al. Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells. Proc Natl Acad Sci U S A 2011; 108:17396-401; PMID:21969579; http://dx.doi.org/10.1073/ pnas.1113421108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 17396-17401
    • Martinez, J.1    Almendinger, J.2    Oberst, A.3    Ness, R.4    Dillon, C.P.5    Fitzgerald, P.6
  • 69
    • 77950275298 scopus 로고    scopus 로고
    • Circulating mitochondrial DAMPs cause inflammatory responses to injury
    • PMID:20203610
    • Zhang Q, Raoof M, Chen Y, Sumi Y, Sursal T, Junger W, et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 2010; 464:104-7; PMID:20203610; http://dx.doi.org/10.1038/nature08780
    • (2010) Nature , vol.464 , pp. 104-107
    • Zhang, Q.1    Raoof, M.2    Chen, Y.3    Sumi, Y.4    Sursal, T.5    Junger, W.6
  • 71
    • 79961167250 scopus 로고    scopus 로고
    • DNA released from dying host cells mediates aluminum adjuvant activity
    • PMID:21765404
    • Marichal T, Ohata K, Bedoret D, Mesnil C, Sabatel C, Kobiyama K, et al. DNA released from dying host cells mediates aluminum adjuvant activity. Nat Med 2011; 17:996-1002; PMID:21765404; http://dx.doi.org/10.1038/nm.2403
    • (2011) Nat Med , vol.17 , pp. 996-1002
    • Marichal, T.1    Ohata, K.2    Bedoret, D.3    Mesnil, C.4    Sabatel, C.5    Kobiyama, K.6
  • 73
    • 84866274756 scopus 로고    scopus 로고
    • Cell death and autophagy under oxidative stress: Roles of poly(ADPRibose) polymerases and Ca(2+)
    • PMID:22751932
    • Wyrsch P, Blenn C, Bader J, Althaus FR. Cell death and autophagy under oxidative stress: Roles of poly(ADPRibose) polymerases and Ca(2+). Mol Cell Biol 2012; 32:3541-53; PMID:22751932; http://dx.doi.org/10.1128/MCB.00437-12
    • (2012) Mol Cell Biol , vol.32 , pp. 3541-3553
    • Wyrsch, P.1    Blenn, C.2    Bader, J.3    Althaus, F.R.4
  • 75
    • 79952270884 scopus 로고    scopus 로고
    • HDACs link the DNA damage response, processing of double-strand breaks and autophagy
    • PMID:21368826
    • Robert T, Vanoli F, Chiolo I, Shubassi G, Bernstein KA, Rothstein R, et al. HDACs link the DNA damage response, processing of double-strand breaks and autophagy. Nature 2011; 471:74-9; PMID:21368826; http://dx.doi.org/10.1038/ nature09803.
    • (2011) Nature , vol.471 , pp. 74-79
    • Robert, T.1    Vanoli, F.2    Chiolo, I.3    Shubassi, G.4    Bernstein, K.A.5    Rothstein, R.6
  • 76
    • 79954549252 scopus 로고    scopus 로고
    • Autophagy-dependent regulation of the DNA damage response protein ribonucleotide reductase 1
    • PMID:21343333
    • Dyavaiah M, Rooney JP, Chittur SV, Lin Q, Begley TJ. Autophagy-dependent regulation of the DNA damage response protein ribonucleotide reductase 1. Mol Cancer Res 2011; 9:462-75; PMID:21343333; http://dx.doi.org/10.1158/1541-7786. MCR-10-0473
    • (2011) Mol Cancer Res , vol.9 , pp. 462-475
    • Dyavaiah, M.1    Rooney, J.P.2    Chittur, S.V.3    Lin, Q.4    Begley, T.J.5
  • 77
    • 84859639962 scopus 로고    scopus 로고
    • Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress
    • PMID:22499945
    • Lee IH, Kawai Y, Fergusson MM, Rovira II, Bishop AJ, Motoyama N, et al. Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. Science 2012; 336:225-8; PMID:22499945; http://dx.doi.org/10.1126/ science.1218395
    • (2012) Science , vol.336 , pp. 225-228
    • Lee, I.H.1    Kawai, Y.2    Fergusson, M.M.3    Rovira, I.I.4    Bishop, A.J.5    Motoyama, N.6
  • 78
    • 34347404887 scopus 로고    scopus 로고
    • Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
    • PMID:17606641
    • Karantza-Wadsworth V, Patel S, Kravchuk O, Chen G, Mathew R, Jin S, et al. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev 2007; 21:1621-35; PMID:17606641; http://dx.doi.org/10. 1101/gad.1565707
    • (2007) Genes Dev , vol.21 , pp. 1621-1635
    • Karantza-Wadsworth, V.1    Patel, S.2    Kravchuk, O.3    Chen, G.4    Mathew, R.5    Jin, S.6
  • 79
    • 84860918805 scopus 로고    scopus 로고
    • A dual role for UVRAG in maintaining chromosomal stability independent of autophagy
    • PMID:22542840
    • Zhao Z, Oh S, Li D, Ni D, Pirooz SD, Lee JH, et al. A dual role for UVRAG in maintaining chromosomal stability independent of autophagy. Dev Cell 2012; 22:1001-16; PMID:22542840; http://dx.doi.org/10.1016/j.devcel.2011.12.027
    • (2012) Dev Cell , vol.22 , pp. 1001-1016
    • Zhao, Z.1    Oh, S.2    Li, D.3    Ni, D.4    Pirooz, S.D.5    Lee, J.H.6
  • 81
    • 77957655181 scopus 로고    scopus 로고
    • The intricacy of nuclear membrane dynamics during nucleophagy
    • PMID:21327066
    • Mijaljica D, Prescott M, Devenish RJ. The intricacy of nuclear membrane dynamics during nucleophagy. Nucleus 2010; 1:213-23; PMID:21327066; http://dx.doi.org/10.4161/nucl.1.3.11738
    • (2010) Nucleus , vol.1 , pp. 213-223
    • Mijaljica, D.1    Prescott, M.2    Devenish, R.J.3
  • 82
    • 84860705893 scopus 로고    scopus 로고
    • Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
    • PMID:22535248
    • Oka T, Hikoso S, Yamaguchi O, Taneike M, Takeda T, Tamai T, et al. Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure. Nature 2012; 485:251-5; PMID:22535248; http://dx.doi.org/10.1038/ nature10992
    • (2012) Nature , vol.485 , pp. 251-255
    • Oka, T.1    Hikoso, S.2    Yamaguchi, O.3    Taneike, M.4    Takeda, T.5    Tamai, T.6
  • 83
    • 79951642032 scopus 로고    scopus 로고
    • Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
    • PMID:21151103
    • Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 2011; 12:222-30; PMID:21151103; http://dx.doi.org/10.1038/ni.1980
    • (2011) Nat Immunol , vol.12 , pp. 222-230
    • Nakahira, K.1    Haspel, J.A.2    Rathinam, V.A.3    Lee, S.J.4    Dolinay, T.5    Lam, H.C.6
  • 84
    • 77957106729 scopus 로고    scopus 로고
    • HMGB1 release and redox regulates autophagy and apoptosis in cancer cells
    • PMID:20622903
    • Tang D, Kang R, Cheh CW, Livesey KM, Liang X, Schapiro NE, et al. HMGB1 release and redox regulates autophagy and apoptosis in cancer cells. Oncogene 2010; 29:5299-310; PMID:20622903; http://dx.doi.org/10.1038/onc.2010.261
    • (2010) Oncogene , vol.29 , pp. 5299-5310
    • Tang, D.1    Kang, R.2    Cheh, C.W.3    Livesey, K.M.4    Liang, X.5    Schapiro, N.E.6
  • 85
    • 48449094878 scopus 로고    scopus 로고
    • ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages
    • PMID:18627610
    • Biswas D, Qureshi OS, Lee WY, Croudace JE, Mura M, Lammas DA. ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages. BMC Immunol 2008; 9:35; PMID:18627610; http://dx.doi.org/10.1186/1471-2172-9-35
    • (2008) BMC Immunol , vol.9 , pp. 35
    • Biswas, D.1    Qureshi, O.S.2    Lee, W.Y.3    Croudace, J.E.4    Mura, M.5    Lammas, D.A.6
  • 86
    • 61449162046 scopus 로고    scopus 로고
    • The activation of P2X7 receptor impairs lysosomal functions and stimulates the release of autophagolysosomes in microglial cells
    • PMID:19201858
    • Takenouchi T, Nakai M, Iwamaru Y, Sugama S, Tsukimoto M, Fujita M, et al. The activation of P2X7 receptor impairs lysosomal functions and stimulates the release of autophagolysosomes in microglial cells. J Immunol 2009; 182:2051-62; PMID:19201858; http://dx.doi.org/10.4049/jimmunol.0802577
    • (2009) J Immunol , vol.182 , pp. 2051-2062
    • Takenouchi, T.1    Nakai, M.2    Iwamaru, Y.3    Sugama, S.4    Tsukimoto, M.5    Fujita, M.6
  • 87
    • 79954459822 scopus 로고    scopus 로고
    • Inflammasomeindependent modulation of cytokine response by autophagy in human cells
    • PMID:21490934
    • Crisan TO, Plantinga TS, van de Veerdonk FL, Farcas MF, Stoffels M, Kullberg BJ, et al. Inflammasomeindependent modulation of cytokine response by autophagy in human cells. PLoS One 2011; 6:e18666; PMID:21490934; http://dx.doi.org/10.1371/journal.pone.0018666
    • (2011) PLoS One , vol.6
    • Crisan, T.O.1    Plantinga, T.S.2    Van De Veerdonk, F.L.3    Farcas, M.F.4    Stoffels, M.5    Kullberg, B.J.6
  • 88
    • 84870781509 scopus 로고    scopus 로고
    • A janus tale of two active high mobility group box 1 (HMGB1) redox states
    • PMID:23073660
    • Tang D, Billiar TR, Lotze MT. A Janus Tale of Two Active High Mobility Group Box 1 (HMGB1) Redox States. Mol Med 2012; 18:1360-2; PMID:23073660; http://dx.doi.org/10.2119/molmed.2012.00314
    • (2012) Mol Med , vol.18 , pp. 1360-1362
    • Tang, D.1    Billiar, T.R.2    Lotze, M.T.3
  • 89
    • 84860163119 scopus 로고    scopus 로고
    • P53/HMGB1 complexes regulate autophagy and apoptosis
    • PMID:22345153
    • Livesey KM, Kang R, Vernon P, Buchser W, Loughran P, Watkins SC, et al. p53/HMGB1 complexes regulate autophagy and apoptosis. Cancer Res 2012; 72:1996-2005; PMID:22345153; http://dx.doi.org/10.1158/0008-5472.CAN-11-2291
    • (2012) Cancer Res , vol.72 , pp. 1996-2005
    • Livesey, K.M.1    Kang, R.2    Vernon, P.3    Buchser, W.4    Loughran, P.5    Watkins, S.C.6
  • 90
    • 84855406005 scopus 로고    scopus 로고
    • HMGB1 promotes drug resistance in osteosarcoma
    • PMID:22102692
    • Huang J, Ni J, Liu K, Yu Y, Xie M, Kang R, et al. HMGB1 promotes drug resistance in osteosarcoma. Cancer Res 2012; 72:230-8; PMID:22102692; http://dx.doi.org/10.1158/0008-5472.CAN-11-2001
    • (2012) Cancer Res , vol.72 , pp. 230-238
    • Huang, J.1    Ni, J.2    Liu, K.3    Yu, Y.4    Xie, M.5    Kang, R.6
  • 91
    • 79958050965 scopus 로고    scopus 로고
    • High-mobility group box 1 is essential for mitochondrial quality control
    • PMID:21641551
    • Tang D, Kang R, Livesey KM, Kroemer G, Billiar TR, Van Houten B, et al. High-mobility group box 1 is essential for mitochondrial quality control. Cell Metab 2011; 13:701-11; PMID:21641551; http://dx.doi.org/10.1016/j.cmet.2011.04. 008
    • (2011) Cell Metab , vol.13 , pp. 701-711
    • Tang, D.1    Kang, R.2    Livesey, K.M.3    Kroemer, G.4    Billiar, T.R.5    Van Houten, B.6
  • 92
    • 78651286142 scopus 로고    scopus 로고
    • HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells. Leukemia: Official journal of the Leukemia Society of America
    • Liu L, Yang M, Kang R, Wang Z, Zhao Y, Yu Y, et al. HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells. Leukemia: Official journal of the Leukemia Society of America. Leukemia Research Fund, UK 2011; 25:23-31; http://dx.doi.org/10.1038/leu.2010.225
    • (2011) Leukemia Research Fund, UK , vol.25 , pp. 23-31
    • Liu, L.1    Yang, M.2    Kang, R.3    Wang, Z.4    Zhao, Y.5    Yu, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.