Intracellular HMGB1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice

Gastroenterology

Volumn 146, Issue 4, 2014, Pages

  Kang, Rui ^a   Zhang, Qiuhong ^a   Hou, Wen ^a   Yan, Zhenwen ^a,b   Chen, Ruochan ^a   Bonaroti, Jillian ^a   Bansal, Preeti ^a   Billiar, Timothy R ^a   Tsung, Allan ^a   Wang, Qingde ^a   Bartlett, David L ^a   Whitcomb, David C ^c   Chang, Eugene B ^d   Zhu, Xiaorong ^d   Wang, Haichao ^e   Lu, Ben ^f   Tracey, Kevin J ^f   Cao, Lizhi ^g   Fan, Xue Gong ^g   Lotze, Michael T ^a   Zeh III, Herbert J ^a   Tang, Daolin ^a   more..

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

^e NORTH SHORE UNIVERSITY HOSPITAL   (United States)

^f FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^g CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

DNA Damage; Nuclear Factor B; Oxidative Stress; Pancreatitis

Indexed keywords

ACETYLCYSTEINE; AMYLASE; ARGININE; CERULETIDE; CRE RECOMBINASE; DNA; GENOMIC DNA; HIGH MOBILITY GROUP B1 PROTEIN; HISTONE H3; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR PDX 1; TRANSCRIPTION FACTOR RELA;

ACINAR CELL; ACUTE PANCREATITIS; AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL INFILTRATION; CONTROLLED STUDY; DNA DAMAGE; EDEMA; ENZYME ACTIVATION; HISTOPATHOLOGY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LEUKOCYTE; LOXP SITE; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOSOME; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION;

DNA DAMAGE; NUCLEAR FACTOR ΚB; OXIDATIVE STRESS; PANCREATITIS;

ACUTE DISEASE; ANIMALS; ARGININE; CELL DEATH; CERULETIDE; DISEASE MODELS, ANIMAL; DNA DAMAGE; HIGH MOBILITY GROUP PROTEINS; HISTONES; IMMUNITY, INNATE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEOSOMES; OXIDATIVE STRESS; PANCREAS; PANCREATITIS; REACTIVE OXYGEN SPECIES; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84896478042     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2013.12.015     Document Type: Article

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