Sterile inflammatory response in acute pancreatitis

Pancreas

Volumn 41, Issue 3, 2012, Pages 353-357

  Hoque, Rafaz ^a   Malik, Ahsan F ^a   Gorelick, Fred ^a   Mehal, Wajahat Z ^a,b  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

caspase 1; DAMP; inflammasome; NLRP3; P2X 7; pancreatitis; TLR4; TLR9

Indexed keywords

ALLOPURINOL; CHLOROQUINE; CRYOPYRIN; DOUBLE STRANDED DNA; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PROBIOTIC AGENT; PURINERGIC P2X7 RECEPTOR; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9;

ACUTE PANCREATITIS; CELL DAMAGE; CYTOKINE PRODUCTION; DISEASE PREDISPOSITION; DISEASE SEVERITY; GENE DELETION; HOST CELL; HUMAN; IMMUNOMODULATION; INFECTION RISK; INFLAMMATION; INNATE IMMUNITY; NONHUMAN; OBESITY; PRIORITY JOURNAL; REVIEW;

ACUTE DISEASE; ANIMALS; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; PANCREAS; PANCREATITIS; SIGNAL TRANSDUCTION;

EID: 84859037979     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0b013e3182321500     Document Type: Review

References (67)

1. Bonilla FA, Oettgen HC. Adaptive immunity. J Allergy Clin Immunol. 2010;125:S33-S40.
2. Chen GY, Nunez G. Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol. 2010;10:826-837.
3. Iyer SS, Pulskens WP, Sadler JJ, et al. Necrotic cells trigger asterile inflammatory response through the Nlrp3 inflammasome. Proc Natl Acad Sci U S A. 2009;106:20388-20393.
4. Piccinini AM, Midwood KS. DAMPening inflammation by modulating TLR signalling. Mediators Inflamm. 2010;2010:672395.
5. Zhang Q, Raoof M, Chen Y, et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature. 2010;464:104-107.
6. Benko S, Philpott DJ, Girardin SE. The microbial and danger signals that activate Nod-like receptors. Cytokine. 2008;43:368-373.
7. Yazdi AS, Guarda G, D'Ombrain MC, et al. Inflammatory caspases ininnate immunity and inflammation. J Innate Immun. 2010;2:228-237.
8. O'Reilly DA, Kingsnorth AN. A brief history of pancreatitis. J R Soc Med. 2001;94:130-132.
9. Sandoval D, Gukovskaya A, Reavey P, et al. The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis. Gastroenterology. 1996;111:1081-1091. (Pubitemid 26327612)
10. Van Laethem JL, Marchant A, Delvaux A, et al. Interleukin 10prevents necrosis in murine experimental acute pancreatitis. Gastroenterology. 1995;108:1917-1922.
11. Adler G, Rohr G, Kern HF. Alteration of membrane fusion as a cause of acute pancreatitis in the rat. Dig Dis Sci. 1982;27:993-1002. (Pubitemid 13233064)
12. Tsung A, Sahai R, Tanaka H, et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med. 2005;201:1135-1143. (Pubitemid 40524681)
13. Yasuda T, Ueda T, Takeyama Y, et al. Significant increase of serum high-mobility group box chromosomal protein 1 levels in patients with severe acute pancreatitis. Pancreas. 2006;33:359-363. (Pubitemid 44690725)
14. Kocsis AK, Szabolcs A, Hofner P, et al. Plasma concentrations of high-mobility group box protein 1, soluble receptor for advanced glycation end-products and circulating DNA in patients with acute pancreatitis. Pancreatology. 2009;9:383-391.
15. Sawa H, Ueda T, Takeyama Y, et al. Blockade of high mobility group box-1 protein attenuates experimental severe acute pancreatitis. World J Gastroenterol. 2006;12:7666-7670. (Pubitemid 46040580)
16. Yuan H, Jin X, Sun J, et al. Protective effect of hMGB1 a box on organ injury of acute pancreatitis in mice. Pancreas. 2009;38:143-148.
17. Song JM, Liu HX, Li Y, et al. Extracellular heat-shock protein 70aggravates cerulein-induced pancreatitis through toll-like receptor-4 in mice. Chin Med J (Engl). 2008;121:1420-1425.
18. McConnell KW, Fox AC, Clark AT, et al. The role of heat shock protein 70 in mediating age-dependent mortality in sepsis. J Immunol. 2011;186:3718-3725.
19. Sharif R, Dawra R, Wasiluk K, et al. Impact of toll-like receptor 4 on the severity of acute pancreatitis and pancreatitis-associated lung injury in mice. Gut. 2009;58:813-819.
20. Ding SQ, Li Y, Zhou ZG, et al. Toll-like receptor 4-mediated apoptosis of pancreatic cells in cerulein-induced acute pancreatitis in mice. Hepatobiliary Pancreat Dis Int. 2010;9:645-650.
21. Li Y, Zhou ZG, Xia QJ, et al. Toll-like receptor 4detected in exocrine pancreas and the change of expression in cerulein-induced pancreatitis. Pancreas. 2005;30:375-381. (Pubitemid 40586819)
22. Imaeda AB, Watanabe A, Sohail MA, et al. Acetaminophen-induced hepatotoxicity inmice is dependent on Tlr9 and the Nalp3 inflammasome. J Clin Invest. 2009;119:305-314.
23. Hoque R, Sohail M, Malik A, et al. TLR9 and the NLRP3 Inflammasome Link Acinar Cell Death With Inflammation in Acute Pancreatitis. Gastroenterology. 2011;141(1):358-369.
24. Nishio A, Asada M, Uchida K, et al. The role of innate immunity in the pathogenesis of experimental autoimmune pancreatitis in mice. Pancreas. 2011;40:95-102.
25. Cook JW, Karakozis S, Kim D, et al. Interleukin-10 attenuates proinflammatory cytokine production and improves survival in lethal pancreatitis. Am Surg. 2001;67:237-241; discussion 232-241.
26. Minter RM, Ferry MA, Murday ME, et al. Adenoviral delivery of human and viral IL-10 in murine sepsis. J Immunol. 2001;167:1053-1059. (Pubitemid 32660864)
27. Duewell P, Kono H, Rayner KJ, et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 2010;464:1357-1361.
28. Ramadani M, Gansauge F, Schlosser S, et al. Overexpression of caspase-1 in pancreatic disorders: implications for a function besides apoptosis. J Gastrointest Surg. 2001;5:352-358. (Pubitemid 33651248)
29. Jin C, Flavell RA. Molecular mechanism of nLRP3 inflammasome activation. J Clin Immunol. 2010;30:628-631.
30. Scheuplein F, Schwarz N, Adriouch S, et al. NAD+ and ATP released from injured cells induce P2X7-dependent shedding of CD62L and externalization of phosphatidylserine by murine T cells. J Immunol. 2009;182:2898-2908.
31. Norman JG, Fink G, Franz M, et al. Active interleukin-1 receptor required for maximal progression of acute pancreatitis. Ann Surg. 1996;223:163-169. (Pubitemid 26065209)
32. Norman J, Franz M, Messina J, et al. Interleukin-1 receptor antagonist decreases severity of experimental acute pancreatitis. Surgery. 1995;117:648-655.
33. Marrache F, Tu SP, Bhagat G, et al. Overexpression of interleukin-1beta in the murine pancreas results in chronic pancreatitis. Gastroenterology. 2008;135:1277-1287.
34. Brivet FG, Emilie D, Galanaud P. Pro- and anti-inflammatory cytokines during acute severe pancreatitis: an early and sustained response, although unpredictable of death. Parisian Study Group on Acute Pancreatitis. Crit Care Med. 1999;27:749-755. (Pubitemid 29218208)
35. Heresbach D, Letourneur JP, Bahon I, et al. Value of early blood Th-1 cytokine determination in predicting severity of acute pancreatitis. Scand J Gastroenterol. 1998;33:554-560. (Pubitemid 28277259)
36. Mayer J, Rau B, Gansauge F, et al. Inflammatory mediators in human acute pancreatitis: clinical and pathophysiological implications. Gut. 2000;47:546-552.
37. Fink GW, Norman JG. Specific changes inthe pancreatic expression of the interleukin 1 family of genes during experimental acute pancreatitis. Cytokine. 1997;9:1023-1027. (Pubitemid 28026669)
38. Norman JG, Fink GW, Denham W, et al. Tissue-specific cytokine production during experimental acute pancreatitis. A probable mechanism for distant organ dysfunction. Dig Dis Sci. 1997;42:1783-1788. (Pubitemid 27394605)
39. Stimac D, Fisic E, Milic S, et al. Prognostic values of iL-6, IL-8, and IL-10 in acute pancreatitis. J Clin Gastroenterol. 2006;40:209-212. (Pubitemid 44309552)
40. Pini M, Sennello JA, Cabay RJ, et al. Effect of diet-induced obesity on acute pancreatitis induced by administration of interleukin-12 plus interleukin-18 in mice. Obesity (Silver Spring). 2010;18:476-481.
41. Sennello JA, Fayad R, Pini M, et al. Interleukin-18, together with interleukin-12, induces severe acute pancreatitis in obese but not in nonobese leptin-deficient mice. Proc Natl Acad Sci U S A. 2008;105:8085-8090. (Pubitemid 351904712)
42. Ueno N, Kashiwamura S, Ueda H, et al. Role of interleukin 18 in nitric oxide production and pancreatic damage during acute pancreatitis. Shock. 2005;24:564-570.
43. Ueda T, Takeyama Y, Yasuda T, et al. Significant elevation of serum interleukin-18 levels in patients with acute pancreatitis. J Gastroenterol. 2006;41:158-165.
44. Rau B, Baumgart K, Paszkowski AS, et al. Clinical relevance of caspase-1 activated cytokines in acute pancreatitis: high correlation of serum interleukin-18 with pancreatic necrosis and systemic complications. Crit Care Med. 2001;29:1556-1562. (Pubitemid 32762336)
45. Wereszczynska-Siemiatkowska U, Mroczko B, Siemiatkowski A. Serum profiles of interleukin-18 in different severity forms of human acute pancreatitis. Scand J Gastroenterol. 2002;37:1097-1102.
46. Aho HJ, Suonpaa K, Ahola RA, et al. Experimental pancreatitis inthe rat. Ductal factors in sodium taurocholate-induced acute pancreatitis. Exp Pathol. 1984;25:73-79. (Pubitemid 14167592)
47. Laukkarinen JM, Van Acker GJ, Weiss ER, et al. A mouse model of acute biliary pancreatitis induced by retrograde pancreatic duct infusion of Na-taurocholate. Gut. 2007;56:1590-1598. (Pubitemid 350033200)
48. Pandol SJ, Periskic S, Gukovsky I, et al. Ethanol diet increases the sensitivity of rats to pancreatitis induced by cholecystokinin octapeptide. Gastroenterology. 1999;117:706-716. (Pubitemid 29409258)
49. Samuel I, Yuan Z, Meyerholz DK, et al. A novel model of severe gallstone pancreatitis: murine pancreatic duct ligation results in systemic inflammation and substantial mortality. Pancreatology. 2010;10:536-544.
50. Rivera CA, Bradford BU, Seabra V, et al. Role of endotoxin in the hypermetabolic state after acute ethanol exposure. Am J Physiol. 1998;275:G1252-G1258.
51. Bailey ME. Endotoxin, bile salts and renal function in obstructive jaundice. Br J Surg. 1976;63:774-778.
52. Wig JD, Kochhar R, Ray JD, et al. Endotoxemia predicts outcome in acute pancreatitis. J Clin Gastroenterol. 1998;26:121-124. (Pubitemid 28173092)
53. Bauernfeind FG, Horvath G, Stutz A, et al. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol. 2009;183:787-791.
54. An H, Xu H, Yu Y, et al. Up-regulation of TLR9 gene expression by LPS in mouse macrophages via activation of NF-kappaB, ERK and p38 MAPK signal pathways. Immunol Lett. 2002;81:165-169. (Pubitemid 34310220)
55. Fink GW, Norman JG. Intrapancreatic interleukin-1beta gene expression by specific leukocyte populations during acute pancreatitis. J Surg Res. 1996;63:369-373. (Pubitemid 26197222)
56. De Nardo D, De Nardo CM, Nguyen T, et al. Signaling crosstalk during sequential TLR4 and TLR9 activation amplifies the inflammatory response of mouse macrophages. J Immunol. 2009;183:8110-8118.
57. Bhan U, Ballinger MN, Zeng X, et al. Cooperative interactions between TLR4 and TLR9 regulate interleukin 23 and 17 production in a murine model of gram-negative bacterial pneumonia. PLoS One. 2010;5:9896.
58. Guillaumes S, Blanco I, Villanueva A, et al. Chloroquine stabilizes pancreatic lysosomes and improves survival of mice with diet-induced acute pancreatitis. Pancreas. 1997;14:262-266. (Pubitemid 27149050)
59. Yasuda H, Leelahavanichkul A, Tsunoda S, et al. Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury. Am J Physiol Renal Physiol. 2008;294:F1050-F1058.
60. Paszkowski AS, Rau B, Mayer JM, et al. Therapeutic application of caspase 1/interleukin-1 beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis. Ann Surg. 2002;235:68-76. (Pubitemid 34062401)
61. Comert B, Isik AT, Aydin S, et al. Combination of allopurinol and hyperbaric oxygen therapy: a new treatment in experimental acute necrotizing pancreatitis? World J Gastroenterol. 2007;13:6203-6207.
62. Martinez-Torres H, Rodriguez-Lomeli X, Davalos-Cobian C, et al. Oral allopurinol toprevent hyperamylasemia and acute pancreatitis after endoscopic retrograde cholangiopancreatography. World J Gastroenterol. 2009;15:1600-1606.
63. Sawa H, Ueda T, Takeyama Y, et al. Role of toll-like receptor 4 in the pathophysiology of severe acute pancreatitis in mice. Surg Today. 2007;37:867-873. (Pubitemid 47459856)
64. Parenti DM, Steinberg W, Kang P. Infectious causes of acute pancreatitis. Pancreas. 1996;13:356-371.
65. Renner IG, Savage WT 3rd, Pantoja JL, et al. Death due toacute pancreatitis. A retrospective analysis of 405 autopsy cases. Dig Dis Sci. 1985;30:1005-1018. (Pubitemid 16225044)
66. Schneider L, Buchler MW, Werner J. Acute pancreatitis with anemphasis on infection. Infect Dis Clin North Am. 2010;24:921-941.
67. Besselink MG, van Santvoort HC, Buskens E, et al. Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial. Lancet. 2008;371:651-659