Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis

Cell Death and Differentiation

Volumn 21, Issue 8, 2014, Pages 1229-1239

  Xu, J ^a,b   Jiang, Y ^b   Wang, J ^a,b   Shi, X ^a,c   Liu, Q ^d,e   Liu, Z ^a,b   Li, Y ^a   Scott, M J ^a   Xiao, G ^f   Li, S ^g   Fan, L ^g   Billiar, T R ^a,g   Wilson, M A ^a,h   Fan, J ^a,g,h  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c XI'AN JIAOTONG UNIVERSITY   (China)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^e HARBIN MEDICAL UNIVERSITY   (China)

^f RUSH UNIVERSITY MEDICAL CENTER   (United States)

^g UNIVERSITY OF PITTSBURGH   (United States)

^h VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 11; CATHEPSIN B; CRYOPYRIN; HIGH MOBILITY GROUP B1 PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; HMGB1 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE; MOK PROTEIN, HUMAN; TUMOR ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL FATE; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; ENDOTOXEMIA; ENZYME ACTIVATION; GENE DELETION; IN VITRO STUDY; INTERNALIZATION; LYSOSOME; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PYROPTOSIS; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CONFOCAL MICROSCOPY; GENETIC TRANSFECTION; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTIGENS, NEOPLASM; APOPTOSIS; ENDOCYTOSIS; HMGB1 PROTEIN; HUMANS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MITOGEN-ACTIVATED PROTEIN KINASES; TRANSFECTION;

EID: 84905053185     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2014.40     Document Type: Article

References (37)

1. Mollen KP, Anand RJ, Tsung A, Prince JM, Levy RM, Billiar TR. Emerging paradigm: Toll-like receptor 4-sentinel for the detection of tissue damage. Shock 2006; 26: 430-437.
2. Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006; 440: 237-241.
3. Wang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science 1999; 285: 248-251.
4. Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundback P et al. Novel role of PKR in inflammasome activation and HMGB1 release. Nature 2012; 488: 670-674.
5. Andersson U, Tracey KJ. HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol 2011; 29: 139-162.
6. Wang H, Yang H, Czura CJ, Sama AE, Tracey KJ. HMGB1 as a late mediator of lethal systemic inflammation. Am J Respir Crit Care Med 2001; 164(10 Pt 1): 1768-1773.
7. Yang H, Wang H, Czura CJ, Tracey KJ. The cytokine activity of HMGB1. J Leukoc Biol 2005; 78: 1-8.
8. Bucciarelli LG, Wendt T, Rong L, Lalla E, Hofmann MA, Goova MT et al. RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic disease. Cell Mol Life Sci 2002; 59: 1117-1128.
9. van Zoelen MA, van der Sluijs KF, Achouiti A, Florquin S, Braun-Pater JM, Yang H et al. Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia. Virology 2009; 391: 265-273.
10. van Zoelen MA, Yang H, Florquin S, Meijers JC, Akira S, Arnold B et al. Role of Toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo. Shock 2009; 31: 280-284.
11. Hofmann MA, Drury S, Fu C, Qu W, Taguchi A, Lu Y et al. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 1999; 97: 889-901.
12. Huttunen HJ, Kuja-Panula J, Sorci G, Agneletti AL, Donato R, Rauvala H. Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation. J Biol Chem 2000; 275: 40096-40105.
13. Toure F, Zahm JM, Garnotel R, Lambert E, Bonnet N, Schmidt AM et al. Receptor for advanced glycation end-products (RAGE) modulates neutrophil adhesion and migration on glycoxidated extracellular matrix. Biochem J 2008; 416: 255-261.
14. Palumbo R, De Marchis F, Pusterla T, Conti A, Alessio M, Bianchi ME. Src family kinases are necessary for cell migration induced by extracellular HMGB1. J Leukoc Biol 2009; 86: 617-623.
15. Bassi R, Giussani P, Anelli V, Colleoni T, Pedrazzi M, Patrone M et al. HMGB1 as an autocrine stimulus in human T98G glioblastoma cells: role in cell growth and migration. J Neuro-Oncol 2008; 87: 23-33.
16. Kim JY, Park HK, Yoon JS, Kim SJ, Kim ES, Ahn KS et al. Advanced glycation end product (AGE)-induced proliferation of HEL cells via receptor for AGE-related signal pathways. Int J Oncol 2008; 33: 493-501.
17. Hudson BI, Kalea AZ, Del Mar Arriero M, Harja E, Boulanger E, D'Agati V et al. Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42. J Biol Chem 2008; 283: 34457-34468.
18. Bergsbaken T, Fink SL, Cookson BT. Pyroptosis: host cell death and inflammation. Nat Rev Microbiol 2009; 7: 99-109.
19. Albert ML. Death-defying immunity: do apoptotic cells influence antigen processing and presentation? Nat Rev Immunol 2004; 4: 223-231.
20. Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 2008; 9: 847-856.
21. Jones LJ, Upson RH, Haugland RP, Panchuk-Voloshina N, Zhou M. Quenched BODIPY dye-labeled casein substrates for the assay of protease activity by direct fluorescence measurement. Anal Biochem 1997; 251: 144-152.
22. Santambrogio L, Sato AK. Carven GJ, Belyanskaya SL, Strominger JL, Stern LJ. Extracellular antigen processing and presentation by immature dendritic cells. Proc Natl Acad Sci USA 1999; 96: 15056-15061.
23. Earnshaw WC, Martins LM, Kaufmann SH. Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem 1999; 68: 383-424.
24. Xiang M, Shi X, Li Y, Xu J, Yin L, Xiao G et al. Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells. J Immunol 2011; 187: 4809-4817.
25. Xu P, Wen Z, Shi X, Li Y, Fan L, Xiang M et al. Hemorrhagic shock augments Nlrp3 inflammasome activation in the lung through impaired pyrin induction. J Immunol 2013; 190: 5247-5255.
26. Stehlik C, Lee SH, Dorfleutner A, Stassinopoulos A, Sagara J, Reed JC. Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation. J Immunol 2003; 171: 6154-6163.
27. Miao EA, Rajan JV, Aderem A. Caspase-1-induced pyroptotic cell death. Immunol Rev 2011; 243: 206-214.
28. Hansen CG, Nichols BJ. Molecular mechanisms of clathrin-independent endocytosis. J Cell Sci 2009; 122(Pt 11): 1713-1721.
29. Bashkirov PV, Akimov SA, Evseev AI, Schmid SL, Zimmerberg J, Frolov VA. GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fission. Cell 2008; 135: 1276-1286.
30. Pucadyil TJ, Schmid SL. Real-time visualization of dynamin-catalyzed membrane fission and vesicle release. Cell 2008; 135: 1263-1275.
31. Roux A, Antonny B. The long and short of membrane fission. Cell 2008; 135: 1163-1165.
32. Hori O, Brett J, Slattery T, Cao R, Zhang J, Chen JX et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J Biol Chem 1995; 270: 25752-25761.
33. Schmidt AM, Hori O, Chen JX, Li JF, Crandall J, Zhang J et al. Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes. J Clin Invest 1995; 96: 1395-1403.
34. Di Guglielmo GM, Le Roy C, Goodfellow AF, Wrana JL. Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover. NatCcell Biol 2003; 5: 410-421.
35. Sigismund S, Argenzio E, Tosoni D, Cavallaro E, Polo S, Di Fiore PP. Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation. Dev Cell 2008; 15: 209-219.
36. Zitvogel L, Kepp O, Kroemer G. Decoding cell death signals in inflammation and immunity. Cell 2010; 140: 798-804.
37. Weischenfeldt J, Porse B. Bone marrow-derived macrophages (BMM): isolation and applications. CSH Protoc 2008; 2008: pdb prot5080.