Significant increase of serum high-mobility group box chromosomal protein 1 levels in patients with severe acute pancreatitis

Pancreas

Volumn 33, Issue 4, 2006, Pages 359-363

  Yasuda, Takeo ^a   Ueda, Takashi ^a   Takeyama, Yoshifumi ^b   Shinzeki, Makoto ^a   Sawa, Hidehiro ^a   Nakajima, Takahiro ^a   Ajiki, Tetsuo ^a   Fujino, Yasuhiro ^a   Suzuki, Yasuyuki ^a   Kuroda, Yoshikazu ^a  

^a KOBE UNIVERSITY   (Japan)

^b KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

HMGB1; Inflammation; Mediator; Organ failure; Severe acute pancreatitis

Indexed keywords

BILIRUBIN; C REACTIVE PROTEIN; CHROMOSOME PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN; LACTATE DEHYDROGENASE;

ACUTE PANCREATITIS; ADULT; ARTICLE; BILIRUBIN BLOOD LEVEL; CHROMOSOME; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HOSPITAL ADMISSION; HUMAN; INFECTION; LACTATE DEHYDROGENASE BLOOD LEVEL; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; RATING SCALE; SCORING SYSTEM; STATISTICAL SIGNIFICANCE;

BACTERIAL INFECTIONS; BILIRUBIN; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; FEMALE; HMGB1 PROTEIN; HUMANS; L-LACTATE DEHYDROGENASE; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; PANCREATITIS; PANCREATITIS, ACUTE NECROTIZING; PROGNOSIS; SEVERITY OF ILLNESS INDEX; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TIME FACTORS;

EID: 33750608337     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mpa.0000236741.15477.8b     Document Type: Article

References (35)

1. Tenner S, Sica G, Hughes M, et al. Relationship of necrosis to organ failure in severe acute pancreatitis. Gastroenterology. 1997;113:899-903.
2. Buter A, Imrie CW, Carter CR, et al. Dynamic nature of early organ dysfunction determines outcome in acute pancreatitis. Br J Surg. 2002;89:298-302.
3. Farkas G, Marton J, Mandi Y, et al. Surgical strategy and management of infected pancreatic necrosis. Br J Surg. 1996;83:930-933.
4. Isenmann R, Rau B, Beger HG. Bacterial infection and extent of necrosis are determinants of organ failure in patients with acute necrotizing pancreatitis. Br J Surg. 1999;86:1020-1024.
5. Goodwin GH, Sanders C, John EW. A new group of chromatin-associated proteins with a high content of acidic and basic amino acids. Eur J Biochem. 1973;38:14-19.
6. Melvin VS, Edwards DP. Coregulatory proteins in steroid hormone receptor action: the role of chromatin high mobility group proteins HMG-1 and -2. Steroids. 1999;64:576-586.
7. Bustin M. Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins. Mol Cell Biol. 1999;19:5237-5246.
8. Wang H, Bloom O, Zhang M, et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science. 1999;285:248-251.
9. Andersson U, Wang H, Palmblad K, et al. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med. 2000;192:565-570.
10. O'Connor KA, Hansen MK, Rachal Pugh C, et al. Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects. Cytokine. 2003;24:254-265.
11. Yang H, Ochani M, Li J, et al. Reversing established sepsis with antagonists of endogenous high-mobility group box 1. Proc Natl Acad Sci U S A. 2004;101:296-301.
12. Sunden-Cullberg J, Norrby-Teglund A, Rouhiainen A, et al. Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock. Crit Care Med. 2005;33:564-573.
13. Ombrellino M, Wang H, Ajemian MS, et al. Increased serum concentrations of high-mobility-group protein 1 in haemorrhagic shock. Lancet. 1999;354:1446-1447.
14. Abraham E, Arcaroli J, Carmody A, et al. HMG-1 as a mediator of acute lung inflammation. J Immunol. 2000;165:2950-2954.
15. Ueno H, Matsuda T, Hashimoto S, et al. Contributions of high mobility group box protein in experimental and clinical acute lung injury. Am J Respir Crit Care Med. 2004;170:1310-1316.
16. Taniguchi N, Kawahara K, Yone K, et al. High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine. Arthritis Rheum. 2003;48:971-981.
17. Hatada T, Wada H, Nobori T, et al. Plasma concentrations and importance of high mobility group box protein in the prognosis of organ failure in patients with disseminated intravascular coagulation. Thromb Haemost. 2005;94:975-979.
18. Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature. 2002;418:191-195.
19. Erlandsson Harris H, Andersson U. Mini-review: the nuclear protein HMGB1 as a proinflammatory mediator. Eur J Immunol. 2004;34:1503-1512.
20. Yang H, Tracey KJ. High mobility group box 1 (HMGB1). Crit Care Med. 2005;33:S472-S474.
21. Ogawa M, Hirota M, Hayakawa T, et al. Development and use of a new staging system for severe acute pancreatitis based on a nationwide survey in Japan. Pancreas. 2002;25:325-330.
22. Ranson JH, Rifkind KM, Roses DF, et al. Prognostic signs and the role of operative management in acute pancreatitis. Surg Gynecol Obstet. 1974;139:69-81.
23. Knaus WA, Draper EA, Wagner DP, et al. APACHE II: a severity of disease classification system. Crit Care Med. 1985;13:818-829.
24. Blamey SL, Imrie CW, O'Neill J, et al. Prognostic factors in acute pancreatitis. Gut. 1984;25:1340-1346.
25. Yamada S, Inoue K, Yakabe K, et al. High mobility group protein 1 (HMGB1) quantified by ELISA with a monoclonal antibody that does not cross-react with HMGB2. Clin Chem. 2003;49:1535-1537.
26. Yang H, Wang H, Trachey KJ. HMG-1 rediscovered as a cytokine. Shock. 2001;15:247-253.
27. Fang WH, Yao YM, Shi ZG, et al. The significance of changes in high mobility group-1 protein mRNA expression in rats after thermal injury. Shock. 2002;17:329-333.
28. Tsung A, Sahai R, Tanaka H, et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med. 2005;201:1135-1143.
29. Fiuza C, Bustin M, Talwar S, et al. Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells. Blood. 2003;101:2652-2660.
30. Sappington PL, Yang R, Yang H, et al. HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice. Gastroenterology. 2002;123:790-802.
31. Hori O, Brett J, Slattery T, et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of RAGE and amphoterin in the developing nervous system. J Biol Chem. 1995;270:25752-25761.
32. Liliensiek B, Weigand MA, Bierhaus A, et al. Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response. J Clin Invest. 2004;113:1641-1650.
33. Park JS, Svetkauskaite D, He Q, et al. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem. 2004;279:7370-7377.
34. Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila toll protein signals activation of adaptive immunity. Nature. 1997;388:394-397.
35. Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science. 1998;282: 2085-2088.