메뉴 건너뛰기




Volumn 303, Issue 9, 2012, Pages

Autophagy and pancreatitis

Author keywords

Cathepsin; Lysosome; Lysosome associated membrane protein; Macroautophagy; Pancreatic acinar cell; Trypsin

Indexed keywords

LYSOSOME ASSOCIATED MEMBRANE PROTEIN;

EID: 84868378549     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00122.2012     Document Type: Review
Times cited : (120)

References (113)
  • 1
    • 0020421817 scopus 로고
    • Alteration of membrane fusion as a cause of acute pancreatitis in the rat
    • Adler G, Rohr G, Kern HF. Alteration of membrane fusion as a cause of acute pancreatitis in the rat. Dig Dis Sci 27: 993-1002, 1982.
    • (1982) Dig Dis Sci , vol.27 , pp. 993-1002
    • Adler, G.1    Rohr, G.2    Kern, H.F.3
  • 2
    • 0020402944 scopus 로고
    • Uptake and degradation of proteins by isolated rat liver lysosomes. Suggestion of a microautophagic pathway of proteolysis
    • Ahlberg J, Marzella L, Glaumann H. Uptake and degradation of proteins by isolated rat liver lysosomes. Suggestion of a microautophagic pathway of proteolysis. Lab Invest 47: 523-532, 1982.
    • (1982) Lab Invest , vol.47 , pp. 523-532
    • Ahlberg, J.1    Marzella, L.2    Glaumann, H.3
  • 4
    • 77952766891 scopus 로고    scopus 로고
    • Autophagy: Assays and artifacts
    • Barth S, Glick D, Macleod KF. Autophagy: assays and artifacts. J Pathol 221: 117-124, 2010.
    • (2010) J Pathol , vol.221 , pp. 117-124
    • Barth, S.1    Glick, D.2    Macleod, K.F.3
  • 5
    • 0022393338 scopus 로고
    • Morphometrical and immunocytochemical studies on rat pancreatic acinar cells under control and experimental conditions
    • Bendayan M, Bruneau A, Morisset J. Morphometrical and immunocytochemical studies on rat pancreatic acinar cells under control and experimental conditions. Biol Cell 54: 227-234, 1985.
    • (1985) Biol Cell , vol.54 , pp. 227-234
    • Bendayan, M.1    Bruneau, A.2    Morisset, J.3
  • 6
    • 79954577494 scopus 로고    scopus 로고
    • Vacuolization of mucolipidosis type II mouse exocrine gland cells represents accumulation of autolysosomes
    • Boonen M, van Meel E, Oorschot V, Klumperman J, Kornfeld S. Vacuolization of mucolipidosis type II mouse exocrine gland cells represents accumulation of autolysosomes. Mol Biol Cell 22: 1135-1147, 2011.
    • (2011) Mol Biol Cell , vol.22 , pp. 1135-1147
    • Boonen, M.1    van Meel, E.2    Oorschot, V.3    Klumperman, J.4    Kornfeld, S.5
  • 7
    • 0020661852 scopus 로고
    • Ultrastructure of early development of acute pancreatitis in the rat
    • Brackett KA, Crocket A, Joffe SN. Ultrastructure of early development of acute pancreatitis in the rat. Dig Dis Sci 28: 74-84, 1983.
    • (1983) Dig Dis Sci , vol.28 , pp. 74-84
    • Brackett, K.A.1    Crocket, A.2    Joffe, S.N.3
  • 11
    • 0029837453 scopus 로고    scopus 로고
    • A receptor for the selective uptake and degradation of proteins by lysosomes
    • Cuervo AM, Dice JF. A receptor for the selective uptake and degradation of proteins by lysosomes. Science 273: 501-503, 1996.
    • (1996) Science , vol.273 , pp. 501-503
    • Cuervo, A.M.1    Dice, J.F.2
  • 12
    • 79958167078 scopus 로고    scopus 로고
    • Functions of autophagy in hepatic and pancreatic physiology and disease
    • Czaja MJ. Functions of autophagy in hepatic and pancreatic physiology and disease. Gastroenterology 140: 1895-1908, 2011.
    • (2011) Gastroenterology , vol.140 , pp. 1895-1908
    • Czaja, M.J.1
  • 13
    • 81855228093 scopus 로고    scopus 로고
    • Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis
    • Dawra R, Sah RP, Dudeja V, Rishi L, Talukdar R, Garg P, Saluja AK. Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis. Gastroenterology 141: 2210-2217, 2011.
    • (2011) Gastroenterology , vol.141 , pp. 2210-2217
    • Dawra, R.1    Sah, R.P.2    Dudeja, V.3    Rishi, L.4    Talukdar, R.5    Garg, P.6    Saluja, A.K.7
  • 18
    • 0024312845 scopus 로고
    • Biosynthesis of lysosomal endopeptidases
    • Erickson AH. Biosynthesis of lysosomal endopeptidases. J Cell Biochem 40: 31-41, 1989.
    • (1989) J Cell Biochem , vol.40 , pp. 31-41
    • Erickson, A.H.1
  • 19
    • 38949136372 scopus 로고    scopus 로고
    • To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy of mammalian cells
    • Eskelinen EL. To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy of mammalian cells. Autophagy 4: 257-260, 2008.
    • (2008) Autophagy , vol.4 , pp. 257-260
    • Eskelinen, E.L.1
  • 20
    • 62949091373 scopus 로고    scopus 로고
    • Autophagy: A lysosomal degradation pathway with a central role in health and disease
    • Eskelinen EL, Saftig P. Autophagy: a lysosomal degradation pathway with a central role in health and disease. Biochim Biophys Acta 1793: 664-673, 2009.
    • (2009) Biochim Biophys Acta , vol.1793 , pp. 664-673
    • Eskelinen, E.L.1    Saftig, P.2
  • 21
    • 0037334339 scopus 로고    scopus 로고
    • At the acidic edge: Emerging functions for lysosomal membrane proteins
    • Eskelinen EL, Tanaka Y, Saftig P. At the acidic edge: emerging functions for lysosomal membrane proteins. Trends Cell Biol 13: 137-145, 2003.
    • (2003) Trends Cell Biol , vol.13 , pp. 137-145
    • Eskelinen, E.L.1    Tanaka, Y.2    Saftig, P.3
  • 22
    • 62949143802 scopus 로고    scopus 로고
    • Burden of digestive diseases in the United States. III. Liver, biliary tract, and pancreas
    • Everhart JE, Ruhl CE. Burden of digestive diseases in the United States. III. Liver, biliary tract, and pancreas. Gastroenterology 136: 1134-1144, 2009.
    • (2009) Gastroenterology , vol.136 , pp. 1134-1144
    • Everhart, J.E.1    Ruhl, C.E.2
  • 24
    • 67649382475 scopus 로고    scopus 로고
    • Impaired autolysosome formation correlates with Lamp-2 depletion: Role of apoptosis, autophagy, and necrosis in pancreatitis
    • Fortunato F, Burgers H, Bergmann F, Rieger P, Buchler MW, Kroemer G, Werner J. Impaired autolysosome formation correlates with Lamp-2 depletion: role of apoptosis, autophagy, and necrosis in pancreatitis. Gastroenterology 137: 350-360, 2009.
    • (2009) Gastroenterology , vol.137 , pp. 350-360
    • Fortunato, F.1    Burgers, H.2    Bergmann, F.3    Rieger, P.4    Buchler, M.W.5    Kroemer, G.6    Werner, J.7
  • 25
    • 80052586196 scopus 로고    scopus 로고
    • Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis
    • Gaiser S, Daniluk J, Liu Y, Tsou L, Chu J, Lee W, Longnecker DS, Logsdon CD, Ji B. Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis. Gut 60: 1379-1388, 2011.
    • (2011) Gut , vol.60 , pp. 1379-1388
    • Gaiser, S.1    Daniluk, J.2    Liu, Y.3    Tsou, L.4    Chu, J.5    Lee, W.6    Longnecker, D.S.7    Logsdon, C.D.8    Ji, B.9
  • 26
    • 79959329467 scopus 로고    scopus 로고
    • Mitochondrial dynamics: A strategy for avoiding autophagy
    • Galluzzi L, Kepp O, Kroemer G. Mitochondrial dynamics: a strategy for avoiding autophagy. Curr Biol 21: R478-R480, 2011.
    • (2011) Curr Biol , vol.21
    • Galluzzi, L.1    Kepp, O.2    Kroemer, G.3
  • 27
    • 0344304559 scopus 로고    scopus 로고
    • Mammalian GGAs act together to sort mannose 6-phosphate receptors
    • Ghosh P, Griffith J, Geuze HJ, Kornfeld S. Mammalian GGAs act together to sort mannose 6-phosphate receptors. J Cell Biol 163: 755-766, 2003.
    • (2003) J Cell Biol , vol.163 , pp. 755-766
    • Ghosh, P.1    Griffith, J.2    Geuze, H.J.3    Kornfeld, S.4
  • 28
    • 0024835412 scopus 로고
    • Crinophagy as a means for degrading excess secretory proteins in rat liver
    • Glaumann H. Crinophagy as a means for degrading excess secretory proteins in rat liver. Revis Biol Celular 20: 97-110, 1989.
    • (1989) Revis Biol Celular , vol.20 , pp. 97-110
    • Glaumann, H.1
  • 29
    • 77950994646 scopus 로고    scopus 로고
    • Autophagy: Cellular and molecular mechanisms
    • Glick D, Barth S, Macleod KF. Autophagy: cellular and molecular mechanisms. J Pathol 221: 3-12, 2010.
    • (2010) J Pathol , vol.221 , pp. 3-12
    • Glick, D.1    Barth, S.2    Macleod, K.F.3
  • 30
    • 0346727127 scopus 로고    scopus 로고
    • Protein degradation and protection against misfolded or damaged proteins
    • Goldberg AL. Protein degradation and protection against misfolded or damaged proteins. Nature 426: 895-899, 2003.
    • (2003) Nature , vol.426 , pp. 895-899
    • Goldberg, A.L.1
  • 33
    • 79959354999 scopus 로고    scopus 로고
    • Mitochondria and the autophagyinflammation-cell death axis in organismal aging
    • Green DR, Galluzzi L, Kroemer G. Mitochondria and the autophagyinflammation-cell death axis in organismal aging. Science 333: 1109-1112, 2011.
    • (2011) Science , vol.333 , pp. 1109-1112
    • Green, D.R.1    Galluzzi, L.2    Kroemer, G.3
  • 34
    • 79958177198 scopus 로고    scopus 로고
    • Which way to die: The regulation of acinar cell death in pancreatitis by mitochondria, calcium, and reactive oxygen species
    • Gukovskaya AS, Gukovsky I. Which way to die: the regulation of acinar cell death in pancreatitis by mitochondria, calcium, and reactive oxygen species. Gastroenterology 140: 1876-1880, 2011.
    • (2011) Gastroenterology , vol.140 , pp. 1876-1880
    • Gukovskaya, A.S.1    Gukovsky, I.2
  • 35
    • 77953693474 scopus 로고    scopus 로고
    • Impaired autophagy underlies key pathological responses of acute pancreatitis
    • Gukovsky I, Gukovskaya AS. Impaired autophagy underlies key pathological responses of acute pancreatitis. Autophagy 6: 428-429, 2010.
    • (2010) Autophagy , vol.6 , pp. 428-429
    • Gukovsky, I.1    Gukovskaya, A.S.2
  • 36
  • 39
    • 14644408674 scopus 로고    scopus 로고
    • Early events in acute pancreatitis
    • Halangk W, Lerch MM. Early events in acute pancreatitis. Clin Lab Med 25: 1-15, 2005.
    • (2005) Clin Lab Med , vol.25 , pp. 1-15
    • Halangk, W.1    Lerch, M.M.2
  • 46
    • 79961011972 scopus 로고    scopus 로고
    • Pathophysiological role of autophagy: Lesson from autophagy-deficient mouse models
    • Ichimura Y, Komatsu M. Pathophysiological role of autophagy: lesson from autophagy-deficient mouse models. Exp Anim 60: 329-345, 2011.
    • (2011) Exp Anim , vol.60 , pp. 329-345
    • Ichimura, Y.1    Komatsu, M.2
  • 47
    • 0036929283 scopus 로고    scopus 로고
    • Processing and activation of lysosomal proteinases
    • Ishidoh K, Kominami E. Processing and activation of lysosomal proteinases. Biol Chem 383: 1827-1831, 2002.
    • (2002) Biol Chem , vol.383 , pp. 1827-1831
    • Ishidoh, K.1    Kominami, E.2
  • 48
    • 81855167439 scopus 로고    scopus 로고
    • Digesting new information about the role of trypsin in pancreatitis
    • Ji B, Logsdon CD. Digesting new information about the role of trypsin in pancreatitis. Gastroenterology 141: 1972-1975, 2011.
    • (2011) Gastroenterology , vol.141 , pp. 1972-1975
    • Ji, B.1    Logsdon, C.D.2
  • 49
    • 79952355107 scopus 로고    scopus 로고
    • Selective autophagy mediated by autophagic adapter proteins
    • Johansen T, Lamark T. Selective autophagy mediated by autophagic adapter proteins. Autophagy 7: 279-296, 2011.
    • (2011) Autophagy , vol.7 , pp. 279-296
    • Johansen, T.1    Lamark, T.2
  • 51
    • 78049513713 scopus 로고    scopus 로고
    • Coxsackievirus infection induces autophagy-like vesicles and megaphagosomes in pancreatic acinar cells in vivo
    • Kemball CC, Alirezaei M, Flynn CT, Wood MR, Harkins S, Kiosses WB, Whitton JL. Coxsackievirus infection induces autophagy-like vesicles and megaphagosomes in pancreatic acinar cells in vivo. J Virol 84: 12110-12124, 2010.
    • (2010) J Virol , vol.84 , pp. 12110-12124
    • Kemball, C.C.1    Alirezaei, M.2    Flynn, C.T.3    Wood, M.R.4    Harkins, S.5    Kiosses, W.B.6    Whitton, J.L.7
  • 53
    • 0023016011 scopus 로고
    • Ultrastructure of pancreatic exocrine cells of the rat during starvation
    • Kitagawa T, Ono K. Ultrastructure of pancreatic exocrine cells of the rat during starvation. Histol Histopathol 1: 49-57, 1986.
    • (1986) Histol Histopathol , vol.1 , pp. 49-57
    • Kitagawa, T.1    Ono, K.2
  • 54
    • 84862295360 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy
    • Klionsky DJ, Abdalla FC, Abeliovich H, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8: 445-544, 2012.
    • (2012) Autophagy , vol.8 , pp. 445-544
    • Klionsky, D.J.1    Abdalla, F.C.2    Abeliovich, H.3
  • 55
    • 0020123582 scopus 로고
    • Pancreatic effects of ethionine: Blockade of exocytosis and appearance of crinophagy and autophagy precede cellular necrosis
    • Koike H, Steer ML, Meldolesi J. Pancreatic effects of ethionine: blockade of exocytosis and appearance of crinophagy and autophagy precede cellular necrosis. Am J Physiol Gastrointest Liver Physiol 242: G297-G307, 1982.
    • (1982) Am J Physiol Gastrointest Liver Physiol , vol.242
    • Koike, H.1    Steer, M.L.2    Meldolesi, J.3
  • 59
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 40: 280-293, 2010.
    • (2010) Mol Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Marino, G.2    Levine, B.3
  • 60
    • 0028129376 scopus 로고
    • Experimental animal models of acute pancreatitis
    • Lerch MM, Adler G. Experimental animal models of acute pancreatitis. Int J Pancreatol 15: 159-170, 1994.
    • (1994) Int J Pancreatol , vol.15 , pp. 159-170
    • Lerch, M.M.1    Adler, G.2
  • 62
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 132: 27-42, 2008.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 67
    • 80052109976 scopus 로고    scopus 로고
    • Interferon regulatory factor-2 regulates exocytosis mechanisms mediated by SNAREs in pancreatic acinar cells
    • Mashima H, Sato T, Horie Y, Nakagawa Y, Kojima I, Ohteki T, Ohnishi H. Interferon regulatory factor-2 regulates exocytosis mechanisms mediated by SNAREs in pancreatic acinar cells. Gastroenterology 141: 1102-1113, 2011.
    • (2011) Gastroenterology , vol.141 , pp. 1102-1113
    • Mashima, H.1    Sato, T.2    Horie, Y.3    Nakagawa, Y.4    Kojima, I.5    Ohteki, T.6    Ohnishi, H.7
  • 68
    • 77955708390 scopus 로고    scopus 로고
    • Overview of macroautophagy regulation in mammalian cells
    • Mehrpour M, Esclatine A, Beau I, Codogno P. Overview of macroautophagy regulation in mammalian cells. Cell Res 20: 748-762, 2010.
    • (2010) Cell Res , vol.20 , pp. 748-762
    • Mehrpour, M.1    Esclatine, A.2    Beau, I.3    Codogno, P.4
  • 69
    • 78649643612 scopus 로고    scopus 로고
    • Missorting of cathepsin B into the secretory compartment of CI-MPR/IGFII-deficient mice does not induce spontaneous trypsinogen activation but leads to enhanced trypsin activity during experimental pancreatitis-without affecting disease severity
    • Meister T, Niehues R, Hahn D, Domschke W, Sendler M, Lerch MM, Schnekenburger J. Missorting of cathepsin B into the secretory compartment of CI-MPR/IGFII-deficient mice does not induce spontaneous trypsinogen activation but leads to enhanced trypsin activity during experimental pancreatitis-without affecting disease severity. J Physiol Pharmacol 61: 565-575, 2010.
    • (2010) J Physiol Pharmacol , vol.61 , pp. 565-575
    • Meister, T.1    Niehues, R.2    Hahn, D.3    Domschke, W.4    Sendler, M.5    Lerch, M.M.6    Schnekenburger, J.7
  • 70
    • 79959999581 scopus 로고    scopus 로고
    • Microautophagy in mammalian cells: Revisiting a 40-year-old conundrum
    • Mijaljica D, Prescott M, Devenish RJ. Microautophagy in mammalian cells: revisiting a 40-year-old conundrum. Autophagy 7: 673-682, 2011.
    • (2011) Autophagy , vol.7 , pp. 673-682
    • Mijaljica, D.1    Prescott, M.2    Devenish, R.J.3
  • 71
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • Mizushima N. Autophagy: process and function. Genes Dev 21: 2861-2873, 2007.
    • (2007) Genes Dev , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 72
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 15: 1101-1111, 2004.
    • (2004) Mol Biol Cell , vol.15 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 73
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 140: 313-326, 2010.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 75
    • 0015971846 scopus 로고
    • Degeneration of mouse pancreatic acinar cells during fasting
    • Nevalainen TJ, Janigan DT. Degeneration of mouse pancreatic acinar cells during fasting. Virchows Arch B Cell Pathol 15: 107-118, 1974.
    • (1974) Virchows Arch B Cell Pathol , vol.15 , pp. 107-118
    • Nevalainen, T.J.1    Janigan, D.T.2
  • 76
    • 84863425313 scopus 로고    scopus 로고
    • p62 at the interface of autophagy, oxidative stress signaling, and cancer
    • Nezis IP, Stenmark H. p62 at the interface of autophagy, oxidative stress signaling, and cancer. Antioxid Redox Signal 17: 786-793, 2012.
    • (2012) Antioxid Redox Signal , vol.17 , pp. 786-793
    • Nezis, I.P.1    Stenmark, H.2
  • 77
    • 0023928419 scopus 로고
    • Intracellular vacuoles in experimental acute pancreatitis in rats and mice are an acidified compartment
    • Niederau C, Grendell JH. Intracellular vacuoles in experimental acute pancreatitis in rats and mice are an acidified compartment. J Clin Invest 81: 229-236, 1988.
    • (1988) J Clin Invest , vol.81 , pp. 229-236
    • Niederau, C.1    Grendell, J.H.2
  • 82
    • 33947318807 scopus 로고    scopus 로고
    • Acute pancreatitis: Bench to the bedside
    • Erratum: ibid, 133:1056
    • Pandol SJ, Saluja AK, Imrie CW, Banks PA. Acute pancreatitis: bench to the bedside. Gastroenterology 132: 1127-1151, 2007. Erratum: ibid, 133:1056.
    • (2007) Gastroenterology , vol.132 , pp. 1127-1151
    • Pandol, S.J.1    Saluja, A.K.2    Imrie, C.W.3    Banks, P.A.4
  • 84
    • 77957855881 scopus 로고    scopus 로고
    • Specialized roles for cysteine cathepsins in health and disease
    • Reiser J, Adair B, Reinheckel T. Specialized roles for cysteine cathepsins in health and disease. J Clin Invest 120: 3421-3431, 2010.
    • (2010) J Clin Invest , vol.120 , pp. 3421-3431
    • Reiser, J.1    Adair, B.2    Reinheckel, T.3
  • 85
    • 34249992834 scopus 로고    scopus 로고
    • Tocotrienols induce apoptosis and autophagy in rat pancreatic stellate cells through the mitochondrial death pathway
    • Rickmann M, Vaquero EC, Malagelada JR, Molero X. Tocotrienols induce apoptosis and autophagy in rat pancreatic stellate cells through the mitochondrial death pathway. Gastroenterology 132: 2518-2532, 2007.
    • (2007) Gastroenterology , vol.132 , pp. 2518-2532
    • Rickmann, M.1    Vaquero, E.C.2    Malagelada, J.R.3    Molero, X.4
  • 88
    • 0026664252 scopus 로고
    • Rat procathepsin. Proteolytic processing to the mature form in vitro
    • Rowan AD, Mason P, Mach L, Mort JS. Rat procathepsin. Proteolytic processing to the mature form in vitro. J Biol Chem 267: 15993-15999, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 15993-15999
    • Rowan, A.D.1    Mason, P.2    Mach, L.3    Mort, J.S.4
  • 89
    • 69249227502 scopus 로고    scopus 로고
    • Lysosome biogenesis and lysosomal membrane proteins: Trafficking meets function
    • Saftig P, Klumperman J. Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat Rev Mol Cell Biol 10: 623-635, 2009.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 623-635
    • Saftig, P.1    Klumperman, J.2
  • 90
    • 80052589208 scopus 로고    scopus 로고
    • Trypsinogen activation in acute and chronic pancreatitis: Is it a prerequisite?
    • Sah RP, Saluja AK. Trypsinogen activation in acute and chronic pancreatitis: is it a prerequisite? Gut 60: 1305-1307, 2011.
    • (2011) Gut , vol.60 , pp. 1305-1307
    • Sah, R.P.1    Saluja, A.K.2
  • 93
    • 0024416027 scopus 로고
    • Pancreatic duct obstruction in rabbits causes digestive zymogen and lysosomal enzyme colocalization
    • Saluja A, Saluja M, Villa A, Leli U, Rutledge P, Meldolesi J, Steer M. Pancreatic duct obstruction in rabbits causes digestive zymogen and lysosomal enzyme colocalization. J Clin Invest 84: 1260-1266, 1989.
    • (1989) J Clin Invest , vol.84 , pp. 1260-1266
    • Saluja, A.1    Saluja, M.2    Villa, A.3    Leli, U.4    Rutledge, P.5    Meldolesi, J.6    Steer, M.7
  • 95
    • 0019501619 scopus 로고
    • Quantitative relationship between autophagy and proteolysis during graded amino acid deprivation in perfused rat liver
    • Schworer CM, Shiffer KA, Mortimore GE. Quantitative relationship between autophagy and proteolysis during graded amino acid deprivation in perfused rat liver. J Biol Chem 256: 7652-7658, 1981.
    • (1981) J Biol Chem , vol.256 , pp. 7652-7658
    • Schworer, C.M.1    Shiffer, K.A.2    Mortimore, G.E.3
  • 99
    • 33745890260 scopus 로고    scopus 로고
    • Review of experimental animal models of acute pancreatitis
    • Su KH, Cuthbertson C, Christophi C. Review of experimental animal models of acute pancreatitis. HPB (Oxford) 8: 264-286, 2006.
    • (2006) HPB (Oxford) , vol.8 , pp. 264-286
    • Su, K.H.1    Cuthbertson, C.2    Christophi, C.3
  • 101
    • 79956095420 scopus 로고    scopus 로고
    • Autophagosome formation and molecular mechanism of autophagy
    • Tanida I. Autophagosome formation and molecular mechanism of autophagy. Antioxid Redox Signal 14: 2201-2214, 2011.
    • (2011) Antioxid Redox Signal , vol.14 , pp. 2201-2214
    • Tanida, I.1
  • 102
    • 0033965924 scopus 로고    scopus 로고
    • Intracellular protein degradation and autophagy in isolated pancreatic acini of the rat
    • Telbisz A, Kovacs AL. Intracellular protein degradation and autophagy in isolated pancreatic acini of the rat. Cell Biochem Funct 18: 29-40, 2000.
    • (2000) Cell Biochem Funct , vol.18 , pp. 29-40
    • Telbisz, A.1    Kovacs, A.L.2
  • 103
    • 0037226735 scopus 로고    scopus 로고
    • VMP1 expression correlates with acinar cell cytoplasmic vacuolization in arginine-induced acute pancreatitis
    • Vaccaro MI, Grasso D, Ropolo A, Iovanna JL, Cerquetti MC. VMP1 expression correlates with acinar cell cytoplasmic vacuolization in arginine-induced acute pancreatitis. Pancreatology 3: 69-74, 2003.
    • (2003) Pancreatology , vol.3 , pp. 69-74
    • Vaccaro, M.I.1    Grasso, D.2    Ropolo, A.3    Iovanna, J.L.4    Cerquetti, M.C.5
  • 104
    • 34447522144 scopus 로고    scopus 로고
    • Cause-effect relationships between zymogen activation and other early events in secretagogue-induced acute pancreatitis
    • Van Acker GJ, Weiss E, Steer ML, Perides G. Cause-effect relationships between zymogen activation and other early events in secretagogue-induced acute pancreatitis. Am J Physiol Gastrointest Liver Physiol 292: G1738-G1746, 2007.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Van Acker, G.J.1    Weiss, E.2    Steer, M.L.3    Perides, G.4
  • 106
    • 79952319773 scopus 로고    scopus 로고
    • Mitochondria removal by autophagy
    • Wang K, Klionsky DJ. Mitochondria removal by autophagy. Autophagy 7: 297-300, 2011.
    • (2011) Autophagy , vol.7 , pp. 297-300
    • Wang, K.1    Klionsky, D.J.2
  • 108
    • 0001563463 scopus 로고
    • Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: Early morphological changes during development of experimental pancreatitis
    • Watanabe O, Baccino FM, Steer ML, Meldolesi J. Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol 246: G457-G467, 1984.
    • (1984) Am J Physiol Gastrointest Liver Physiol , vol.246
    • Watanabe, O.1    Baccino, F.M.2    Steer, M.L.3    Meldolesi, J.4
  • 110
    • 77951920963 scopus 로고    scopus 로고
    • Genetic aspects of pancreatitis
    • Whitcomb DC. Genetic aspects of pancreatitis. Annu Rev Med 61: 413-424, 2010.
    • (2010) Annu Rev Med , vol.61 , pp. 413-424
    • Whitcomb, D.C.1
  • 111
    • 0024403314 scopus 로고
    • Immunocytochemical and morphometric analysis of acinar zymogen granules in human acute pancreatitis
    • Willemer S, Kloppel G, Kern HF, Adler G. Immunocytochemical and morphometric analysis of acinar zymogen granules in human acute pancreatitis. Virchows Arch A Pathol Anat Histopathol 415: 115-123, 1989.
    • (1989) Virchows Arch A Pathol Anat Histopathol , vol.415 , pp. 115-123
    • Willemer, S.1    Kloppel, G.2    Kern, H.F.3    Adler, G.4
  • 112
    • 77951217000 scopus 로고    scopus 로고
    • Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase
    • Wu YT, Tan HL, Shui G, Bauvy C, Huang Q, Wenk MR, Ong CN, Codogno P, Shen HM. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J Biol Chem 285: 10850-10861, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 10850-10861
    • Wu, Y.T.1    Tan, H.L.2    Shui, G.3    Bauvy, C.4    Huang, Q.5    Wenk, M.R.6    Ong, C.N.7    Codogno, P.8    Shen, H.M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.