Alteration in inflammatory/apoptotic pathway and histone modifications by nordihydroguaiaretic acid prevents acute pancreatitis in swiss albino mice

Apoptosis

Volumn 16, Issue 11, 2011, Pages 1138-1149

  Mahajan, Ujwal Mukund ^a   Gupta, Chanchal ^a   Wagh, Preshit Ravindra ^a   Karpe, Pinakin Arun ^a   Tikoo, Kulbhushan ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Acute pancreatitis; Apoptosis; Histone H3 modifications; Inflammation; Necrosis; Oxidative stress

Indexed keywords

CASPASE 3; CERULETIDE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; HISTONE H3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NORDIHYDROGUAIARETIC ACID; PROCASPASE 3; PROTEIN BCL 2; SYNAPTOPHYSIN;

ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HISTONE MODIFICATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; WESTERN BLOTTING;

ACUTE DISEASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; CAERULEIN; CASPASE 3; CHAPERONIN 60; HISTONES; IN SITU NICK-END LABELING; INFLAMMATION; LIPOXYGENASE INHIBITORS; MALE; MICE; MITOCHONDRIAL PROTEINS; NF-KAPPA B; NORDIHYDROGUAIARETIC ACID; OXIDATIVE STRESS; PANCREAS; PANCREATITIS; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 82955162458     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0643-8     Document Type: Article

References (60)

1. Bhatia M, Wong FL, Cao Y et al (2005) Pathophysiology of acute pancreatitis. Pancreatology 5:132-144 (Pubitemid 40754730)
2. Tamizhselvi R, Sun J, Koh YH, Bhatia M (2009) Effect of hydrogen sulfide on the phosphatidylinositol 3-kinase-protein kinase B pathway and on caerulein-induced cytokine production in isolated mouse pancreatic acinar cells. J Pharmacol Exp Ther 329:1166-1177
3. Shi C, Andersson R, Zhao X, Wang X (2005) Potential role of reactive oxygen species in pancreatitis-associated multiple organ dysfunction. Pancreatology 5:492-500 (Pubitemid 41160293)
4. Bokoch G, Knaus U (2003) NADPH oxidases: not just for leukocytes anymore. Trends Biochem Sci 28:502-508 (Pubitemid 38340415)
5. Masamune A, Watanabe T, Kikuta K, Satoh K, Shimosegawa T (2008) NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells. Am J Physiol-Gastrointest Liver Physiol 294:G99-G108
6. Kim SY, Kim TB, Moon KA et al (2008) Regulation of pro-inflammatory responses by lipoxygenases via intracellular reactive oxygen species in vitro and in vivo. Exp Mol Med 40:461-476
7. Li N, Karin M (1999) Is NF-kappaB the sensor of oxidative stress? FASEB J 13:1137-1143
8. Escobar J, Pereda J, Arduini A et al (2009) Cross-talk between oxidative stress and pro-inflammatory cytokines in acute pancreatitis: a key role for protein phosphatases. Curr Pharm Des 15:3027-3042
9. Arasaki K, Tani K, Yoshimori T, Stephens DJ, Tagaya M (2007) Nordihydroguaiaretic acid affects multiple dynein-dynactin functions in interphase and mitotic cells. Mol Pharmacol 71:454-460 (Pubitemid 46147912)
10. Lee CH, Jang YS, Her SJ, Moon YM, Baek SJ, Eling T (2003) Nordihydroguaiaretic acid, an antioxidant, inhibits transforming growth factor-[beta] activity through the inhibition of Smad signaling pathway. Exp Cell Res 289:335-341 (Pubitemid 37117419)
11. West M, Mhatre M, Ceballos A et al (2004) The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor activation of microglia and extends survival of G93A-SOD1 transgenic mice. J Neurochem 91:133-143 (Pubitemid 39314944)
12. Goetzl EJ (1980) A role for endogenous mono-hydroxy-eicosa-tetraenoic acids (HETEs) in the regulation of human neutrophil migration. Immunology 40:709-719 (Pubitemid 10035036)
13. Ito H, Ueda H, Iwamoto I et al (2004) Nordihydroguaiaretic acid (NDGA) blocks the differentiation of C2C12 myoblast cells. J Cell Physiol 202:874-879
14. Youngren JF, Gable K, Penaranda C et al (2005) Nord-ihydroguaiaretic acid (NDGA) inhibits the IGF-1 and c-erbB2/ HER2/neu receptors and suppresses growth in breast cancer cells. Breast Cancer Res Treat 94:37-46 (Pubitemid 41416940)
15. Ansar S, Iqbal M, Athar M (1999) Nordihydroguairetic acid is a potent inhibitor of ferric-nitrilotriacetate-mediated hepatic and renal toxicity and renal tumour promotion in mice. Carcinogen-esis 20:599-606 (Pubitemid 29151295)
16. Floriano-Sánchez E, Villanueva C, Medina-Campos ON et al (2006) Nordihydroguaiaretic acid is a potent in vitro scavenger of peroxynitrite, singlet oxygen, hydroxyl radical, superoxide anion and hypochlorous acid and prevents in vivo ozone-induced tyrosine nitration in lungs. Free Radic Res 40:523-533
17. Yam-Canul P, Chirino YI, Sánchez-González DJ et al (2008) Nordihydroguaiaretic acid attenuates potassium dichromate-induced oxidative stress and nephrotoxicity. Food Chem Toxicol 46:1089-1096
18. Rillema JA (1984) Effect of NDGA, a lipoxygenase inhibitor, on prolactin actions in mouse mammary gland explants. Prosta-glandins Leukot Med 16:89-94 (Pubitemid 14012728)
19. Ryan CJ, Zavodovskaya M, Youngren JF et al (2008) Inhibitory effects of nordihydroguaiaretic acid (NDGA) on the IGF-1 receptor and androgen dependent growth of LAPC-4 prostate cancer cells. Prostate 68:1232-1240
20. Meyer GE, Chesler L, Liu D et al (2007) Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells. J Cell Biochem 102: 1529-1541 (Pubitemid 350223954)
21. Sandoval J, Pereda J, Rodriguez JL et al (2010) Ordered tran-scriptional factor recruitment and epigenetic regulation of tnf-α in necrotizing acute pancreatitis. Cell Mol Life Sci 67:1687-1697
22. Bhaumik SR, Smith E, Shilatifard A (2007) Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14:1008-1016 (Pubitemid 350060343)
23. Kouzarides T (2007) Chromatin modifications and their function. Cell 128:693-705 (Pubitemid 46273577)
24. Mazzon E, Genovese T, Di Paola R et al (2006) Effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) polymer-ase, in a mouse model of acute pancreatitis induced by cerulein. Eur J Pharmacol 549:149-156 (Pubitemid 44441255)
25. Reif AE, Nabseth DC (1962) Serum amylase determination by Somogyi's amyloclastic method with use of photometric end point. Clin Chem 8:113-129
26. Mullane K, Kraemer R, Smith B (1985) Myeloperoxidase activity as an assessment of neutrophil infiltration into ischemic myocardium. J Pharmacol Methods 14:157-167 (Pubitemid 15241170)
27. Kono Y (1978) Generatin of superoxide radical during autoxi-dation of hydroxylamine and assay of superoxide dismutase. Arch Biochem Biophys 186:189-195 (Pubitemid 8290500)
28. Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82:70-77
29. Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351-358 (Pubitemid 9194347)
30. Tikoo K, Meena RL, Kabra DG, Gaikwad AB (2008) Change in post-translational modifications of histone H3, heat-shock pro-tein-27 and MAP kinase p38 expression by curcumin in strep-tozotocin-induced type I diabetic nephropathy. Br J Pharmacol 153:1225-1235
31. Villagra A, Cheng F, Wang HW et al (2009) The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance. Nat Immunol 10:92-100
32. Gomez G, Lee HM, He Q, Englander EW, Uchida T, Greeley GH Jr (2001) Acute pancreatitis signals activation of apoptosis-associated and survival genes in mice. Exp Biol Med 226: 692-700 (Pubitemid 32619609)
33. Rakonczay Z Jr, Takacs T, Boros I, Lonovics J (2003) Heat shock proteins and the pancreas. J Cell Physiol 195:383-391 (Pubitemid 36529866)
34. Chen X, Ji B, Han B, Ernst SA, Simeone D, Logsdon CD (2002) NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response. Gastroenterology 122: 448-457 (Pubitemid 34116996)
35. Williard DE, Twaita E, Yuan Z, Carter B, Samuel I (2010) Nuclear factor kappa B-dependent gene transcription in chole-cystokinin- and tumor necrosis factor stimulated isolated acinar cells is regulated by p38 mitogen-activated protein kinase. Am J Surg 200:283-290
36. Bhatia M (2004) Apoptosis versus necrosis in acute pancreatitis. Am J Physiol Gastrointest Liver Physiol 286:G189-G196 (Pubitemid 38134029)
37. Odinokova IV, Sung KF, Mareninova OA, Hermann K, Gukov-sky I, Gukovskaya AS (2008) Mitochondrial mechanisms of death responses in pancreatitis. J Gastroenterol Hepatol 23: S25-S30 (Pubitemid 351389019)
38. Sung KF, Odinokova IV, Mareninova OA et al (2009) Prosur-vival Bcl-2 proteins stabilize pancreatic mitochondria and protect against necrosis in experimental pancreatitis. Exp Cell Res 315:1975-1989
39. Silverstein AM, Barrow CA, Davis AJ, Mumby MC (2002) Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits. Proc Natl Acad Sci 99:4221-4226 (Pubitemid 34285967)
40. Damuni Z, Xiong H, Li M (1994) Autophosphorylation-activated protein kinase inactivates the protein tyrosine phosphatase activity of protein phosphatase 2A. FEBS Lett 352:311-314
41. Cohen GM (1997) Caspases: the executioners of apoptosis. Biochem J 326:1-16 (Pubitemid 27386911)
42. Berger SL (2007) The complex language of chromatin regulation during transcription. Nature 447:407-412 (Pubitemid 46816746)
43. Wei Y, Yu L, Bowen J, Gorovsky M, Allis C (1999) Phosphor-ylation of histone H3 is required for proper chromosome condensation and segregation. Cell 99:99-109 (Pubitemid 29165893)
44. Sauve D, Anderson H, Ray J, James W, Roberge M (1999) Phosphorylation- induced rearrangement of the histone H3 NH2-terminal domain during mitotic chromosome condensation. J Cell Biol 145:225-235 (Pubitemid 29198297)
45. Tikoo K, Lau SS, Monks TJ (2001) Histone H3 phosphorylation is coupled to poly-(ADPRibosylation) during reactive oxygen species-induced cell death in renal proximal tubular epithelial cells. Mol Pharmacol 60:394-402 (Pubitemid 32678306)
46. Richter K, Haslbeck M, Buchner J (2010) The heat shock response: life on the verge of death. Mol Cell 40:253-266
47. Weber H, Wagner AC, Jonas L et al (2000) Heat shock response is associated with protection against acute interstitial pancreatitis in rats. Dig Dis Sci 45:2252-2264 (Pubitemid 32060402)
48. Okuyama A, Otaka M, Otani S et al (1996) Expression of a 60-kDa and a 72-kDa heat shock protein in rat pancreas after hyperthermia. J Gastroenterol 31:143-145 (Pubitemid 26048488)
49. Kubisch C, Dimagno MJ, Tietz AB et al (2004) Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis. Gastroenterology 127:275-286 (Pubitemid 38962294)
50. Lee BS, Chen J, Angelidis C, Jurivich DA, Morimoto RI (1995) Pharmacological modulation of heat shock factor 1 by antiin-flammatory drugs results in protection against stress-induced cellular damage. Proc Natl Acad Sci 92:7207-7211
51. Szabolcs A, Biczo G, Rakonczay Z et al (2009) Simultaneous proteosome inhibition and heat shock protein induction by bort-ezomib is beneficial in experimental pancreatitis. Eur J Pharmacol 616:270-274
52. Pereda J, Sabater L, Aparisi L et al (2006) Interaction between cytokines and oxidative stress in acute pancreatitis. Curr Med Chem 13:2775-2787 (Pubitemid 44509724)
53. Mareninova OA, Sung KF, Hong P et al (2006) Cell death in pancreatitis: caspases protect from necrotizing pancreatitis. J Biol Chem 281:3370-3381 (Pubitemid 43845951)
54. Parrizas M, Saltiel AR, LeRoith D (1997) Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways. J Biol Chem 272:154-161 (Pubitemid 27021138)
55. Shimizu S, Eguchi Y, Kamiike W et al (1998) Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux. Proc Natl Acad Sci 95:1455-1459 (Pubitemid 28103413)
56. Tsujimoto Y, Shimizu S (2007) Role of the mitochondrial membrane permeability transition in cell death. Apoptosis 12:835-840 (Pubitemid 46653286)
57. Ray RM, Bhattacharya S, Johnson LR (2005) Protein phospha-tase 2A regulates apoptosis in intestinal epithelial cells. J Biol Chem 280:31091-31100 (Pubitemid 41291844)
58. Kabra DG, Gupta J, Tikoo K (2009) Insulin induced alteration in post-translational modifications of histone H3 under a hypergly-cemic condition in L6 skeletal muscle myoblasts. Biochim Bio-phys Acta 1792:574-583
59. Nguyen CT, Weisenberger DJ, Velicescu M et al (2002) Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxy-cytidine. Cancer Res 62:6456-6461 (Pubitemid 35364106)
60. Yan C, Boyd DD (2006) Histone H3 acetylation and H3 K4 methylation define distinct chromatin regions permissive for transgene expression. Mol Cell Biol 26:6357-6371 (Pubitemid 44277877)