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Volumn 35, Issue 1, 2015, Pages 85-125

Moonlighting Adenosine Deaminase: A Target Protein for Drug Development

Author keywords

Adenosine deaminase; Adenosine receptors; Allosteric modulator; CD26; Moonlighting proteins

Indexed keywords

ADENOSINE DEAMINASE; ADENOSINE DEAMINASE 1; ADENOSINE DEAMINASE 2; ADENOSINE RECEPTOR; DIPEPTIDYL PEPTIDASE IV; ISOENZYME; MOONLIGHTING PROTEIN; UNCLASSIFIED DRUG;

EID: 84915779253     PISSN: 01986325     EISSN: 10981128     Source Type: Journal    
DOI: 10.1002/med.21324     Document Type: Article
Times cited : (57)

References (398)
  • 1
    • 0000943397 scopus 로고
    • The deaminases of adenosine and adenylic acid in blood and tissues
    • Conway EJ, Cooke R. The deaminases of adenosine and adenylic acid in blood and tissues. Biochem J 1939;33:479-492.
    • (1939) Biochem J , vol.33 , pp. 479-492
    • Conway, E.J.1    Cooke, R.2
  • 2
    • 84864820568 scopus 로고
    • Adenosine deaminase
    • Brady T. Adenosine deaminase. Biochem J 1942;36:478-484.
    • (1942) Biochem J , vol.36 , pp. 478-484
    • Brady, T.1
  • 3
    • 84876373418 scopus 로고    scopus 로고
    • Adenosine kinase: Exploitation for therapeutic gain
    • Boison D. Adenosine kinase: Exploitation for therapeutic gain. Pharmacol Rev 2013;65:906-943.
    • (2013) Pharmacol Rev , vol.65 , pp. 906-943
    • Boison, D.1
  • 4
    • 79955977181 scopus 로고    scopus 로고
    • Adenosine and the regulation of metabolism and body temperature
    • Fredholm BB, Johansson S, Wang YW. Adenosine and the regulation of metabolism and body temperature. Adv Pharmacol 2011;61:77-94.
    • (2011) Adv Pharmacol , vol.61 , pp. 77-94
    • Fredholm, B.B.1    Johansson, S.2    Wang, Y.W.3
  • 5
    • 79952033865 scopus 로고    scopus 로고
    • International Union of basic and clinical pharmacology. LXXXI. Nomenclature and classification of adenosine receptors-an update
    • Fredholm BB, Ijzerman AP, Jacobson KA, Linden J, Muller CE. International Union of basic and clinical pharmacology. LXXXI. Nomenclature and classification of adenosine receptors-an update. Pharmacol Rev 2011;63:1-34.
    • (2011) Pharmacol Rev , vol.63 , pp. 1-34
    • Fredholm, B.B.1    Ijzerman, A.P.2    Jacobson, K.A.3    Linden, J.4    Muller, C.E.5
  • 6
    • 70349329858 scopus 로고    scopus 로고
    • Adenosine receptors and the kidney
    • Vallon V, Osswald H. Adenosine receptors and the kidney. Handb Exp Pharmacol 2009;193:443-470.
    • (2009) Handb Exp Pharmacol , vol.193 , pp. 443-470
    • Vallon, V.1    Osswald, H.2
  • 7
    • 84867504772 scopus 로고    scopus 로고
    • Adenosine A2 receptor-mediated regulation of renal hemodynamics and glomerular filtration rate is abolished in diabetes
    • Persson P, Hansell P, Palm F. Adenosine A2 receptor-mediated regulation of renal hemodynamics and glomerular filtration rate is abolished in diabetes. Adv Exp Med Biol 2013;765:225-230.
    • (2013) Adv Exp Med Biol , vol.765 , pp. 225-230
    • Persson, P.1    Hansell, P.2    Palm, F.3
  • 8
    • 34748869257 scopus 로고    scopus 로고
    • Role of pulmonary adenosine during hypoxia: Extracellular generation, signaling and metabolism by surface adenosine deaminase/CD 26
    • Van Linden A, Eltzschig HK. Role of pulmonary adenosine during hypoxia: Extracellular generation, signaling and metabolism by surface adenosine deaminase/CD 26. Expert Opin Biol Ther 2007;7:1437-1447.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 1437-1447
    • Van Linden, A.1    Eltzschig, H.K.2
  • 10
    • 78649423015 scopus 로고    scopus 로고
    • Adenosine and inosine release during hypoxia in the isolated spinal cord of neonatal rats
    • Takahashi T, Otsugoro K, Ohta T, Ito S. Adenosine and inosine release during hypoxia in the isolated spinal cord of neonatal rats. Br J Pharmacol 2010;161:1806-1816.
    • (2010) Br J Pharmacol , vol.161 , pp. 1806-1816
    • Takahashi, T.1    Otsugoro, K.2    Ohta, T.3    Ito, S.4
  • 11
    • 84885474113 scopus 로고    scopus 로고
    • Adenosine signaling in airways: Toward a promising antiasthmatic approach
    • Cicala C, Ialenti A. Adenosine signaling in airways: Toward a promising antiasthmatic approach. Eur J Pharmacol 2013;714:522-525.
    • (2013) Eur J Pharmacol , vol.714 , pp. 522-525
    • Cicala, C.1    Ialenti, A.2
  • 12
    • 67650912060 scopus 로고    scopus 로고
    • Cardioprotection induced by adenosine A1 receptor agonists in a cardiac cell ischemia model involves cooperative activation of adenosine A2A and A2B receptors by endogenous adenosine
    • Urmaliva VB, Church JE, Coupar IM, RoseMeyer RB, Pouton CW, White PJ. Cardioprotection induced by adenosine A1 receptor agonists in a cardiac cell ischemia model involves cooperative activation of adenosine A2A and A2B receptors by endogenous adenosine. J Cardiovasc Pharmacol 2009;53:424-433.
    • (2009) J Cardiovasc Pharmacol , vol.53 , pp. 424-433
    • Urmaliva, V.B.1    Church, J.E.2    Coupar, I.M.3    RoseMeyer, R.B.4    Pouton, C.W.5    White, P.J.6
  • 13
    • 84878620093 scopus 로고    scopus 로고
    • Attenuating myocardial ischemia by targeting A2B adenosine receptors
    • Eltzschig HK, Bonney SK, Eckle T. Attenuating myocardial ischemia by targeting A2B adenosine receptors. Trends Mol Med 2013;19:345-354.
    • (2013) Trends Mol Med , vol.19 , pp. 345-354
    • Eltzschig, H.K.1    Bonney, S.K.2    Eckle, T.3
  • 14
    • 84862073627 scopus 로고    scopus 로고
    • A2A adenosine receptor signaling in lymphocytes and the central nervous system regulates inflammation during experimental autoimmune encephalomyelitis
    • Mills JH, Kim DG Krenz A Chen JF, Bynoe MS. A2A adenosine receptor signaling in lymphocytes and the central nervous system regulates inflammation during experimental autoimmune encephalomyelitis. J Immunol 2012;188:5713-5722.
    • (2012) J Immunol , vol.188 , pp. 5713-5722
    • Mills, J.H.1    Kim, D.G.2    Krenz, A.3    Chen, J.F.4    Bynoe, M.S.5
  • 15
    • 84888385324 scopus 로고    scopus 로고
    • Immunity, inflammation and cancer: A leading role for adenosine
    • Antonioli L, Blandizzi C, Pacher P, Haskó G. Immunity, inflammation and cancer: A leading role for adenosine. Nat Rev Cancer 2013;13:842-857.
    • (2013) Nat Rev Cancer , vol.13 , pp. 842-857
    • Antonioli, L.1    Blandizzi, C.2    Pacher, P.3    Haskó, G.4
  • 16
    • 84877615153 scopus 로고    scopus 로고
    • Adenosine as an endogenous immunoregulator in cancer pathogenesis: Where to go?
    • Kumar V. Adenosine as an endogenous immunoregulator in cancer pathogenesis: Where to go? Purinergic Signal 2013;9:145-165.
    • (2013) Purinergic Signal , vol.9 , pp. 145-165
    • Kumar, V.1
  • 18
    • 79954503213 scopus 로고    scopus 로고
    • Adenosine and related drugs in brain diseases: Present and future in clinical trials
    • Lopes LV, Sebastiao AM, Ribeiro JA. Adenosine and related drugs in brain diseases: Present and future in clinical trials. Curr Top Med Chem 2011;11:1087-1101.
    • (2011) Curr Top Med Chem , vol.11 , pp. 1087-1101
    • Lopes, L.V.1    Sebastiao, A.M.2    Ribeiro, J.A.3
  • 19
    • 38649097860 scopus 로고    scopus 로고
    • Adenosine as a neuromodulator in neurological diseases
    • Boison D. Adenosine as a neuromodulator in neurological diseases. Curr Opin Pharmacol 2008;8:2-7.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 2-7
    • Boison, D.1
  • 20
    • 79954507325 scopus 로고    scopus 로고
    • The role of extracellular adenosine in chemical neurotransmission in the hippocampus and basal ganglia: Pharmacological and clinical aspects
    • Sperlagh B, Vizi ES. The role of extracellular adenosine in chemical neurotransmission in the hippocampus and basal ganglia: Pharmacological and clinical aspects. Curr Top Med Chem 2011;11:1034-1046.
    • (2011) Curr Top Med Chem , vol.11 , pp. 1034-1046
    • Sperlagh, B.1    Vizi, E.S.2
  • 21
    • 0036046427 scopus 로고    scopus 로고
    • Does caffeine intake protect from Alzheimer's disease?
    • Maia L, de Mendonca A.
    • Maia L, de Mendonca A. Does caffeine intake protect from Alzheimer's disease? Eur J Neurol 2002;9:377-382.
    • (2002) Eur J Neurol , vol.9 , pp. 377-382
  • 22
    • 3042729591 scopus 로고    scopus 로고
    • Increased homocysteine and decreased adenosine formation in Alzheimer's disease
    • Selley ML. Increased homocysteine and decreased adenosine formation in Alzheimer's disease. Neurol Res 2004;26:554-557.
    • (2004) Neurol Res , vol.26 , pp. 554-557
    • Selley, M.L.1
  • 23
    • 0037161283 scopus 로고    scopus 로고
    • Caffeinated clues and the promise of adenosine A(2A) antagonists in PD
    • Schwarzschild MA, Chen JF, Ascherio A. Caffeinated clues and the promise of adenosine A(2A) antagonists in PD. Neurology 2002;58:1154-1160.
    • (2002) Neurology , vol.58 , pp. 1154-1160
    • Schwarzschild, M.A.1    Chen, J.F.2    Ascherio, A.3
  • 25
    • 77955353133 scopus 로고    scopus 로고
    • Pathophysiological roles for purines: Adenosine, caffeine and urate
    • Morelli M, Carta AR, Kachroo A, Schwarzschild MA. Pathophysiological roles for purines: Adenosine, caffeine and urate. Prog Brain Res 2010;183:183-208.
    • (2010) Prog Brain Res , vol.183 , pp. 183-208
    • Morelli, M.1    Carta, A.R.2    Kachroo, A.3    Schwarzschild, M.A.4
  • 26
    • 0030774744 scopus 로고    scopus 로고
    • Adenosine-dopamine interactions in the ventral striatum. Implications for the treatment of schizophrenia
    • Ferré S. Adenosine-dopamine interactions in the ventral striatum. Implications for the treatment of schizophrenia. Psychopharmacology (Berl) 1997;133:107-120.
    • (1997) Psychopharmacology (Berl) , vol.133 , pp. 107-120
    • Ferré, S.1
  • 27
    • 42649141228 scopus 로고    scopus 로고
    • Potential role of adenosine A2A receptors in the treatment of schizophrenia
    • Wardas J. Potential role of adenosine A2A receptors in the treatment of schizophrenia. Front Biosci 2008;13:4071-4096.
    • (2008) Front Biosci , vol.13 , pp. 4071-4096
    • Wardas, J.1
  • 28
    • 0344483876 scopus 로고    scopus 로고
    • The intrastratial injection of an adenosine A(2) receptor antagonist prevents frontal cortex EEG abnormalities in a rat model of Huntington's disease
    • Reggio R, Pezzola A, Popoli P. The intrastratial injection of an adenosine A(2) receptor antagonist prevents frontal cortex EEG abnormalities in a rat model of Huntington's disease. Brain Res 1999;831:315-318.
    • (1999) Brain Res , vol.831 , pp. 315-318
    • Reggio, R.1    Pezzola, A.2    Popoli, P.3
  • 29
    • 47349089093 scopus 로고    scopus 로고
    • A critical evaluation of adenosine A2A receptors as potentially "druggable" targets in Huntington's disease
    • Popoli P, Blum D, Domenici MR, Burnouf S, Chern Y. A critical evaluation of adenosine A2A receptors as potentially "druggable" targets in Huntington's disease. Curr Pharm Des 2008;14:1500-1511.
    • (2008) Curr Pharm Des , vol.14 , pp. 1500-1511
    • Popoli, P.1    Blum, D.2    Domenici, M.R.3    Burnouf, S.4    Chern, Y.5
  • 31
    • 21844450198 scopus 로고    scopus 로고
    • Long-term effect of convulsive behavior on the density of adenosine A1 and A2A receptors in the rat cerebral cortex
    • Rebola N, Porciuncula LO, Lopes LV, Richardson PJ, Oliveira CR, Cunha RA. Long-term effect of convulsive behavior on the density of adenosine A1 and A2A receptors in the rat cerebral cortex. Epilepsia 2005;46:159-165.
    • (2005) Epilepsia , vol.46 , pp. 159-165
    • Rebola, N.1    Porciuncula, L.O.2    Lopes, L.V.3    Richardson, P.J.4    Oliveira, C.R.5    Cunha, R.A.6
  • 32
    • 84862317564 scopus 로고    scopus 로고
    • Adenosine dysfunction in epilepsy
    • Boison D. Adenosine dysfunction in epilepsy. Glia 2012;60:1234-1243.
    • (2012) Glia , vol.60 , pp. 1234-1243
    • Boison, D.1
  • 34
    • 0032189022 scopus 로고    scopus 로고
    • Decreased presynaptic sensitivity to adenosine after cocaine withdrawal
    • Manzoni O, Pujalte D, Williams J, Bockaert J. Decreased presynaptic sensitivity to adenosine after cocaine withdrawal. J Neurosci 1998;18:7996-8002.
    • (1998) J Neurosci , vol.18 , pp. 7996-8002
    • Manzoni, O.1    Pujalte, D.2    Williams, J.3    Bockaert, J.4
  • 35
    • 0035024509 scopus 로고    scopus 로고
    • Adenosine agonists CGS 21680 and NECA inhibit the initiation of cocaine self-administration
    • Knapp CM, Foye MM, Cottam N, Ciraulo DA, Kornetsky C. Adenosine agonists CGS 21680 and NECA inhibit the initiation of cocaine self-administration. Pharmacol Biochem Behav 2001;68:797-803.
    • (2001) Pharmacol Biochem Behav , vol.68 , pp. 797-803
    • Knapp, C.M.1    Foye, M.M.2    Cottam, N.3    Ciraulo, D.A.4    Kornetsky, C.5
  • 36
    • 54949150308 scopus 로고    scopus 로고
    • Adenosine A(2A) receptors and their role in drug addiction
    • Brown RM, Short JL. Adenosine A(2A) receptors and their role in drug addiction. J Pharm Pharmacol 2008;60:1409-1430.
    • (2008) J Pharm Pharmacol , vol.60 , pp. 1409-1430
    • Brown, R.M.1    Short, J.L.2
  • 40
    • 33644770260 scopus 로고    scopus 로고
    • Adenosine receptors as therapeutic targets
    • Jacobson KA, Gao ZG. Adenosine receptors as therapeutic targets. Nat Rev Drug Discov 2006;5:247-264.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 247-264
    • Jacobson, K.A.1    Gao, Z.G.2
  • 42
    • 84861116203 scopus 로고    scopus 로고
    • Adenosine inhibits glutamatergic input to basal forebrain cholinergic neurons
    • Hawryluk JM, Ferrari LL, Keating SA, Arrigoni E. Adenosine inhibits glutamatergic input to basal forebrain cholinergic neurons. J Neurophysiol 2012;107:2769-2781.
    • (2012) J Neurophysiol , vol.107 , pp. 2769-2781
    • Hawryluk, J.M.1    Ferrari, L.L.2    Keating, S.A.3    Arrigoni, E.4
  • 44
    • 84880426005 scopus 로고    scopus 로고
    • Ecto-5'-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions
    • Augusto E, Matos M, Sevigny J, El-Tayeb A, Bynoe MS, Muller CE, Cunha RA, Chen JF. Ecto-5'-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions. J Neurosci 2013;33:11390-11399.
    • (2013) J Neurosci , vol.33 , pp. 11390-11399
    • Augusto, E.1    Matos, M.2    Sevigny, J.3    El-Tayeb, A.4    Bynoe, M.S.5    Muller, C.E.6    Cunha, R.A.7    Chen, J.F.8
  • 46
    • 77951247730 scopus 로고    scopus 로고
    • Structural basis for the growth factor activity of human adenosine deaminase ADA2
    • Zavialov AV, Yu X, Spillman D, Lauvau G, Zavialov AV. Structural basis for the growth factor activity of human adenosine deaminase ADA2. J Biol Chem 2010;285:12367-12377.
    • (2010) J Biol Chem , vol.285 , pp. 12367-12377
    • Zavialov, A.V.1    Yu, X.2    Spillman, D.3    Lauvau, G.4    Zavialov, A.V.5
  • 47
    • 28244477635 scopus 로고    scopus 로고
    • Phylogenetic analysis reveals a novel protein family closely related to adenosine deaminase
    • Maier SA, Galellis JR, McDermid HE. Phylogenetic analysis reveals a novel protein family closely related to adenosine deaminase. J Mol Evol 2005;61:776-794.
    • (2005) J Mol Evol , vol.61 , pp. 776-794
    • Maier, S.A.1    Galellis, J.R.2    McDermid, H.E.3
  • 48
    • 35848949789 scopus 로고    scopus 로고
    • Adenosine deaminase-related genes: Molecular identification, tissue expression pattern and truncated alternative splice isoform in adult zebrafish (Danio rerio)
    • Rosemberg DB, Rico EP, Guidoti MR, Dias RD, Souza DO, Bonan CD, Bogo MR. Adenosine deaminase-related genes: Molecular identification, tissue expression pattern and truncated alternative splice isoform in adult zebrafish (Danio rerio). Life Sci 2007;81:1526-1534.
    • (2007) Life Sci , vol.81 , pp. 1526-1534
    • Rosemberg, D.B.1    Rico, E.P.2    Guidoti, M.R.3    Dias, R.D.4    Souza, D.O.5    Bonan, C.D.6    Bogo, M.R.7
  • 49
    • 33645113651 scopus 로고    scopus 로고
    • N6-methyl-AMP aminohydrolase activates N6-substituted purine acyclic nucleoside phosphonates
    • Schinkmanova M, Votruba I, Holy A. N6-methyl-AMP aminohydrolase activates N6-substituted purine acyclic nucleoside phosphonates. Biochem Pharmacol 2006;71:1370-1376.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1370-1376
    • Schinkmanova, M.1    Votruba, I.2    Holy, A.3
  • 50
    • 43049123187 scopus 로고    scopus 로고
    • Human N6-methyl-AMP/DAMP aminohydrolase (abacavir 5'-monophosphate deaminase) is capable of metabolizing N6-substituted purine acyclic nucleoside phosphonates
    • Schinkmanova M, Votruba I, Shibata R, Han B, Liu X, Cihlar T, Holy A. Human N6-methyl-AMP/DAMP aminohydrolase (abacavir 5'-monophosphate deaminase) is capable of metabolizing N6-substituted purine acyclic nucleoside phosphonates. Collect Czech Chem Commun 2008;73:275-291.
    • (2008) Collect Czech Chem Commun , vol.73 , pp. 275-291
    • Schinkmanova, M.1    Votruba, I.2    Shibata, R.3    Han, B.4    Liu, X.5    Cihlar, T.6    Holy, A.7
  • 53
    • 0019457232 scopus 로고
    • Comparison and possible homology of isozymes of adenosine deaminase in aves and humans
    • Ratech H, Thorbecke GJ, Meredith G, Hirschhorn R. Comparison and possible homology of isozymes of adenosine deaminase in aves and humans. Enzyme 1981;26:74-84.
    • (1981) Enzyme , vol.26 , pp. 74-84
    • Ratech, H.1    Thorbecke, G.J.2    Meredith, G.3    Hirschhorn, R.4
  • 54
    • 26844457398 scopus 로고    scopus 로고
    • Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity
    • Zavialov AV, Engstrom A. Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity. Biochem J 2005;391:51-57.
    • (2005) Biochem J , vol.391 , pp. 51-57
    • Zavialov, A.V.1    Engstrom, A.2
  • 55
    • 0019466071 scopus 로고
    • Serum adenosine deaminase in normals and in a patient with adenosine deaminase deficient severe combined immunodeficiency
    • Ratech H, Hirschhorn R. Serum adenosine deaminase in normals and in a patient with adenosine deaminase deficient severe combined immunodeficiency. Clin Chim Acta 1981;115:341-347.
    • (1981) Clin Chim Acta , vol.115 , pp. 341-347
    • Ratech, H.1    Hirschhorn, R.2
  • 56
    • 0025898452 scopus 로고
    • Structure-activity relationships of ligands of human plasma adenosine deaminase 2
    • Niedzwicki JG, Abernethy DR. Structure-activity relationships of ligands of human plasma adenosine deaminase 2. Biochem Pharmacol 1991;41:1615-1624.
    • (1991) Biochem Pharmacol , vol.41 , pp. 1615-1624
    • Niedzwicki, J.G.1    Abernethy, D.R.2
  • 58
    • 33645037767 scopus 로고    scopus 로고
    • Human plasma adenosine deaminase 2 is secreted by activated monocytes
    • Iwaki-Egawa S, Yamamoto T, Watanabe Y. Human plasma adenosine deaminase 2 is secreted by activated monocytes. Biol Chem 2006;387:319-321.
    • (2006) Biol Chem , vol.387 , pp. 319-321
    • Iwaki-Egawa, S.1    Yamamoto, T.2    Watanabe, Y.3
  • 59
    • 4644336281 scopus 로고    scopus 로고
    • Macrophages are a source of extracellular adenosine deaminase-2 during inflammatory responses
    • Conlon BA, Law WR. Macrophages are a source of extracellular adenosine deaminase-2 during inflammatory responses. Clin Exp Immunol 2004;138:14-20.
    • (2004) Clin Exp Immunol , vol.138 , pp. 14-20
    • Conlon, B.A.1    Law, W.R.2
  • 60
    • 77956417545 scopus 로고    scopus 로고
    • Human adenosine deaminase 2 induces differentiation of monocytes and stimulates proliferation of T helper cells and macrophages
    • Zavialov AV, Gracia E, Glaichenhaus N, Franco R, Zavialov AV, Lauvau G. Human adenosine deaminase 2 induces differentiation of monocytes and stimulates proliferation of T helper cells and macrophages. J Leuk Biol 2010;88:279-290.
    • (2010) J Leuk Biol , vol.88 , pp. 279-290
    • Zavialov, A.V.1    Gracia, E.2    Glaichenhaus, N.3    Franco, R.4    Zavialov, A.V.5    Lauvau, G.6
  • 61
    • 0034520181 scopus 로고    scopus 로고
    • Determination of adenosine deaminase activity and its isoenzymes for diagnosis of pleural effusions
    • Gorguner M, Cerci M, Gorguner I. Determination of adenosine deaminase activity and its isoenzymes for diagnosis of pleural effusions. Respirology 2000;5:321-324.
    • (2000) Respirology , vol.5 , pp. 321-324
    • Gorguner, M.1    Cerci, M.2    Gorguner, I.3
  • 63
    • 0017360775 scopus 로고
    • Tight-binding inhibitors-IV. Inhibition of adenosine deaminases by various inhibitors
    • Agarwal RP, Spector T, Parks RE Jr. Tight-binding inhibitors-IV. Inhibition of adenosine deaminases by various inhibitors. Biochem Pharmacol 1977;26:359-367.
    • (1977) Biochem Pharmacol , vol.26 , pp. 359-367
    • Agarwal, R.P.1    Spector, T.2    Parks Jr, R.E.3
  • 64
    • 0025339049 scopus 로고
    • Automated enzymatic measurement of adenosine deaminase isoenzyme activities in serum
    • Muraoka T, Katsuramaki T, Shiraishi H, Yokoyama MM. Automated enzymatic measurement of adenosine deaminase isoenzyme activities in serum. Anal Biochem 1990;187:268-272.
    • (1990) Anal Biochem , vol.187 , pp. 268-272
    • Muraoka, T.1    Katsuramaki, T.2    Shiraishi, H.3    Yokoyama, M.M.4
  • 66
    • 0035831287 scopus 로고    scopus 로고
    • Tryptophan environment in adenosine deaminase. I: Enzyme dodification with N-bromosuccinimide in the presence of adenosine and EHNA analogs
    • Mardanyan S, Sharoyan S, Antonyan A, Armenyan A, Cristalli G, Lupidi G. Tryptophan environment in adenosine deaminase. I: Enzyme dodification with N-bromosuccinimide in the presence of adenosine and EHNA analogs. Biochim Biophys Acta 2001;1546:185-195.
    • (2001) Biochim Biophys Acta , vol.1546 , pp. 185-195
    • Mardanyan, S.1    Sharoyan, S.2    Antonyan, A.3    Armenyan, A.4    Cristalli, G.5    Lupidi, G.6
  • 68
    • 0033986761 scopus 로고    scopus 로고
    • Causes and consequences of tumour acidity and implications for treatment
    • Stubbs M, McSheehy PM, Griffiths JR, Bashford CL. Causes and consequences of tumour acidity and implications for treatment. Mol Med Today 2000;6:15-19.
    • (2000) Mol Med Today , vol.6 , pp. 15-19
    • Stubbs, M.1    McSheehy, P.M.2    Griffiths, J.R.3    Bashford, C.L.4
  • 69
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004;4:71-78.
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 70
    • 2542432162 scopus 로고    scopus 로고
    • Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A2A receptors
    • Sitkovsky MV, Lukashev D, Apasov S, Kojima H, Koshiba M, Caldwell C, Ohta A, Thiel M. Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A2A receptors. Annu Rev Immunol 2004;22:657-682.
    • (2004) Annu Rev Immunol , vol.22 , pp. 657-682
    • Sitkovsky, M.V.1    Lukashev, D.2    Apasov, S.3    Kojima, H.4    Koshiba, M.5    Caldwell, C.6    Ohta, A.7    Thiel, M.8
  • 71
  • 72
    • 0019509057 scopus 로고
    • An immunomorphologic study of adenosine deaminase distribution in human thymus tissue, normal lymphocytes, and hematopoietic cell lines
    • Chechik BE, Schrader WP, Minowada J. An immunomorphologic study of adenosine deaminase distribution in human thymus tissue, normal lymphocytes, and hematopoietic cell lines. J Immunol 1981;126:1003-1007.
    • (1981) J Immunol , vol.126 , pp. 1003-1007
    • Chechik, B.E.1    Schrader, W.P.2    Minowada, J.3
  • 73
    • 0023154463 scopus 로고
    • New assignment of the adenosine deaminase gene locus to chromosome 20q13 × 11 by study of a patient with interstitial deletion 20q
    • Petersen MB, Tranebjaerg L, Tommerup N, Nygaard P, Edwards H. New assignment of the adenosine deaminase gene locus to chromosome 20q13 × 11 by study of a patient with interstitial deletion 20q. J Med Genet 1987;24:93-96.
    • (1987) J Med Genet , vol.24 , pp. 93-96
    • Petersen, M.B.1    Tranebjaerg, L.2    Tommerup, N.3    Nygaard, P.4    Edwards, H.5
  • 77
    • 0032212320 scopus 로고    scopus 로고
    • Human monocytoid leukemia cells are highly sensitive to apoptosis induced by 2'-deoxycoformycin and 2'-deoxyadenosine: Association with dATP-dependent activation of caspase-3
    • Niitsu N, Yamaguchi Y, Umeda M, Honma Y. Human monocytoid leukemia cells are highly sensitive to apoptosis induced by 2'-deoxycoformycin and 2'-deoxyadenosine: Association with dATP-dependent activation of caspase-3. Blood 1998;92:3368-3375.
    • (1998) Blood , vol.92 , pp. 3368-3375
    • Niitsu, N.1    Yamaguchi, Y.2    Umeda, M.3    Honma, Y.4
  • 78
    • 0034616645 scopus 로고    scopus 로고
    • The importance of adenosine deaminase for lymphocyte development and function
    • Aldrich MB, Blacburn MR, Kellems RE. The importance of adenosine deaminase for lymphocyte development and function. Biochem Biophys Res Commun 2000;272:311-315.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 311-315
    • Aldrich, M.B.1    Blacburn, M.R.2    Kellems, R.E.3
  • 80
    • 13444262230 scopus 로고    scopus 로고
    • Adenosine deaminase deficiency: Metabolic basis of immune deficiency and pulmonary inflammation
    • Blackburn MR, Kellems RE. Adenosine deaminase deficiency: Metabolic basis of immune deficiency and pulmonary inflammation. Adv Immunol 2005;86:1-41.
    • (2005) Adv Immunol , vol.86 , pp. 1-41
    • Blackburn, M.R.1    Kellems, R.E.2
  • 81
    • 38049014318 scopus 로고    scopus 로고
    • Enzymatic and extraenzymatic role of adenosine deaminase 1 in T-cell-dendritic cell contacts and in alterations of the immune function
    • Franco R, Pacheco R, Gatell JM, Gallart T, Lluís C. Enzymatic and extraenzymatic role of adenosine deaminase 1 in T-cell-dendritic cell contacts and in alterations of the immune function. Crit Rev Immunol 2007;27:495-509.
    • (2007) Crit Rev Immunol , vol.27 , pp. 495-509
    • Franco, R.1    Pacheco, R.2    Gatell, J.M.3    Gallart, T.4    Lluís, C.5
  • 82
    • 79959551775 scopus 로고    scopus 로고
    • High levels of adenosine deaminase on dendritic cells promote autoreactive T cell activation and diabetes in nonobese diabetic mice
    • Ghaemi
    • Ghaemi Oskouie FG, Shameli A, Yang A, Desrosiers MD, Mucsi AD, Blacburn MR, Yang Y, Santamaria P, Shi Y. High levels of adenosine deaminase on dendritic cells promote autoreactive T cell activation and diabetes in nonobese diabetic mice. J Immunol 2011;186:6798-6806.
    • (2011) J Immunol , vol.186 , pp. 6798-6806
    • Oskouie, F.G.1    Shameli, A.2    Yang, A.3    Desrosiers, M.D.4    Mucsi, A.D.5    Blacburn, M.R.6    Yang, Y.7    Santamaria, P.8    Shi, Y.9
  • 83
    • 84860800094 scopus 로고    scopus 로고
    • Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders
    • Antonioli L, Colucci R, La Motta C, Tuccori M, Awward O, Da Settimo F, Blandizzi C, Fornai M. Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders. Curr Drug Target 2012;13:842-862.
    • (2012) Curr Drug Target , vol.13 , pp. 842-862
    • Antonioli, L.1    Colucci, R.2    La Motta, C.3    Tuccori, M.4    Awward, O.5    Da Settimo, F.6    Blandizzi, C.7    Fornai, M.8
  • 84
    • 33746611084 scopus 로고    scopus 로고
    • Recent progress in the development of adenosine receptor ligands as anti-inflammatory drugs
    • Akkari R, Burbiel JC, Hockemeyer J, Müller CE. Recent progress in the development of adenosine receptor ligands as anti-inflammatory drugs. Curr Top Med Chem 2006;6:1375-1399.
    • (2006) Curr Top Med Chem , vol.6 , pp. 1375-1399
    • Akkari, R.1    Burbiel, J.C.2    Hockemeyer, J.3    Müller, C.E.4
  • 85
    • 0017348912 scopus 로고
    • Hereditary hemolytic anemia with increased red cell adenosine deaminase (45- to 70-fold) and decreased adenosine triphosphate
    • Valentine WN, Paglia DE, Tartaglia AP, Gilsanz F. Hereditary hemolytic anemia with increased red cell adenosine deaminase (45- to 70-fold) and decreased adenosine triphosphate. Science 1977;195:783-785.
    • (1977) Science , vol.195 , pp. 783-785
    • Valentine, W.N.1    Paglia, D.E.2    Tartaglia, A.P.3    Gilsanz, F.4
  • 86
    • 0021045343 scopus 로고
    • Elevated erythrocyte adenosine deaminase activity in congenital hypoplastic anemia
    • Glader BE, Backer K, Diamond LK. Elevated erythrocyte adenosine deaminase activity in congenital hypoplastic anemia. N Engl J Med 1983;309:1486-1490.
    • (1983) N Engl J Med , vol.309 , pp. 1486-1490
    • Glader, B.E.1    Backer, K.2    Diamond, L.K.3
  • 87
    • 0024319921 scopus 로고
    • Erythrocyte adenosine deaminase overproduction in hereditary haemolytic anemia
    • Chottiner EG, Ginsburg D, Tartaglia AP, Mitchell BS. Erythrocyte adenosine deaminase overproduction in hereditary haemolytic anemia. Blood 1989;74:448-453.
    • (1989) Blood , vol.74 , pp. 448-453
    • Chottiner, E.G.1    Ginsburg, D.2    Tartaglia, A.P.3    Mitchell, B.S.4
  • 89
    • 2042437071 scopus 로고    scopus 로고
    • Diamond Blackfan anaemia in the UK: Clinical and genetic heterogeneity
    • Orfali KA, Ohene-Abuakwa Y, Ball SE. Diamond Blackfan anaemia in the UK: Clinical and genetic heterogeneity. Br J Haematol 2004;125:243-252.
    • (2004) Br J Haematol , vol.125 , pp. 243-252
    • Orfali, K.A.1    Ohene-Abuakwa, Y.2    Ball, S.E.3
  • 91
    • 0033913703 scopus 로고    scopus 로고
    • The use of adenosine deaminase and adenosine deaminase isoenzymes in the diagnosis of tuberculous pleuritis
    • Pérez-Rodríguez E, Jiménez-Castro D. The use of adenosine deaminase and adenosine deaminase isoenzymes in the diagnosis of tuberculous pleuritis. Curr Opin Pulm Med 2000;6:259-266.
    • (2000) Curr Opin Pulm Med , vol.6 , pp. 259-266
    • Pérez-Rodríguez, E.1    Jiménez-Castro, D.2
  • 92
    • 0036139072 scopus 로고    scopus 로고
    • The possible role of cerebrospinal fluid adenosine deaminase activity in the diagnosis of tuberculous meningitis in adults
    • Choi SH, Kim YS, Bae IG, Chung JW, Lee MS, Kang JM, Ryu J, Woo JH. The possible role of cerebrospinal fluid adenosine deaminase activity in the diagnosis of tuberculous meningitis in adults. Clin Neurol Neurosurg 2002;104:10-15.
    • (2002) Clin Neurol Neurosurg , vol.104 , pp. 10-15
    • Choi, S.H.1    Kim, Y.S.2    Bae, I.G.3    Chung, J.W.4    Lee, M.S.5    Kang, J.M.6    Ryu, J.7    Woo, J.H.8
  • 94
    • 59549085300 scopus 로고    scopus 로고
    • The diagnostic utility of adenosine deaminase isoenzymes in tuberculous pleural effusions
    • Zemlin AE, Burgess LJ, Carstens ME. The diagnostic utility of adenosine deaminase isoenzymes in tuberculous pleural effusions. Int J Tuberc Lung Dis 2009;13:214-220.
    • (2009) Int J Tuberc Lung Dis , vol.13 , pp. 214-220
    • Zemlin, A.E.1    Burgess, L.J.2    Carstens, M.E.3
  • 95
    • 77953651125 scopus 로고    scopus 로고
    • Use of pleural fluid levels of adenosine deaminase and interferon gamma in the diagnosis of tuberculous pleuritis
    • Krenke R, Korczynski P. Use of pleural fluid levels of adenosine deaminase and interferon gamma in the diagnosis of tuberculous pleuritis. Curr Opin Pulm Med 2010;16:367-375.
    • (2010) Curr Opin Pulm Med , vol.16 , pp. 367-375
    • Krenke, R.1    Korczynski, P.2
  • 96
    • 84862488767 scopus 로고    scopus 로고
    • Diagnostic accuracy of adenosine deaminase and lymphocyte proportion in pleural fluid for tuberculous pleurisy in different prevalence scenarios
    • Garcia-Zamalloa A, Taboada-Gomez J. Diagnostic accuracy of adenosine deaminase and lymphocyte proportion in pleural fluid for tuberculous pleurisy in different prevalence scenarios. PLoS One 2012;7:e38729.
    • (2012) PLoS One , vol.7 , pp. e38729
    • Garcia-Zamalloa, A.1    Taboada-Gomez, J.2
  • 97
    • 0035198809 scopus 로고    scopus 로고
    • Adenosine deaminase activity and its isoenzyme pattern in patients with juvenile rheumatoid arthritis and systemic lupus erythematosus
    • Hitoglou S, Hatzistilianou M, Gougoustamou D, Athanassiadou F, Kotsis A, Catriu D. Adenosine deaminase activity and its isoenzyme pattern in patients with juvenile rheumatoid arthritis and systemic lupus erythematosus. Clin Rheumathol 2001;20:411-416.
    • (2001) Clin Rheumathol , vol.20 , pp. 411-416
    • Hitoglou, S.1    Hatzistilianou, M.2    Gougoustamou, D.3    Athanassiadou, F.4    Kotsis, A.5    Catriu, D.6
  • 99
    • 79960101569 scopus 로고    scopus 로고
    • Adenosine deaminase activity in patients with Crohn's disease: Distinction between active and nonactive disease
    • Maor I, Rainis T, Lanir A, Lavy A. Adenosine deaminase activity in patients with Crohn's disease: Distinction between active and nonactive disease. Eur J Gastroenterol Hepatol 2011;23:598-602.
    • (2011) Eur J Gastroenterol Hepatol , vol.23 , pp. 598-602
    • Maor, I.1    Rainis, T.2    Lanir, A.3    Lavy, A.4
  • 103
    • 84863988003 scopus 로고    scopus 로고
    • Serum adenosine deaminase may predict disease activity in rheumatoid arthritis
    • Zamani B, Jamali R, Jamali A. Serum adenosine deaminase may predict disease activity in rheumatoid arthritis. Rheumatol Int 2012;32:1967-1975.
    • (2012) Rheumatol Int , vol.32 , pp. 1967-1975
    • Zamani, B.1    Jamali, R.2    Jamali, A.3
  • 104
    • 33744820828 scopus 로고    scopus 로고
    • Does adenosine deaminase play a key role in coronary artery disease
    • Tang R, Ma Ch, Dong JZ, Liu XP, Liu X. Does adenosine deaminase play a key role in coronary artery disease. Med Hypotheses 2006;67:371-374.
    • (2006) Med Hypotheses , vol.67 , pp. 371-374
    • Tang, R.1    Ma, C.2    Dong, J.Z.3    Liu, X.P.4    Liu, X.5
  • 107
    • 0025923635 scopus 로고
    • Plasma adenosine deaminase 2 is a marker for human immunodeficiency virus-1 seroconversion
    • Niedzwicki JG, Mayer KH, Abushanab E, Abernethy DR. Plasma adenosine deaminase 2 is a marker for human immunodeficiency virus-1 seroconversion. Am J Hematol 1991;37:152-155.
    • (1991) Am J Hematol , vol.37 , pp. 152-155
    • Niedzwicki, J.G.1    Mayer, K.H.2    Abushanab, E.3    Abernethy, D.R.4
  • 108
    • 0031569543 scopus 로고    scopus 로고
    • Adenosine deaminase binding to human CD26 is inhibited by HIV-1 envelope glycoprotein gp120 and viral particles
    • Valenzuela A, Blanco J, Callebaut C, Jacotot E, Lluis C, Hovanessian AG, Franco R. Adenosine deaminase binding to human CD26 is inhibited by HIV-1 envelope glycoprotein gp120 and viral particles. J Immunol 1997;158:3721-3729.
    • (1997) J Immunol , vol.158 , pp. 3721-3729
    • Valenzuela, A.1    Blanco, J.2    Callebaut, C.3    Jacotot, E.4    Lluis, C.5    Hovanessian, A.G.6    Franco, R.7
  • 110
    • 79960319698 scopus 로고    scopus 로고
    • Analysis of serum adenosine deaminase (ADA) and ADA1 and ADA2 isoenzyme activities in HIV positive and HIV-HBV co-infected patients
    • Khodadadi I, Abdi M, Ahmadi A, Wahedi MS, Menbari S, Lahoopour F, Rahbari R. Analysis of serum adenosine deaminase (ADA) and ADA1 and ADA2 isoenzyme activities in HIV positive and HIV-HBV co-infected patients. Clin Biochem 2011;44:980-983.
    • (2011) Clin Biochem , vol.44 , pp. 980-983
    • Khodadadi, I.1    Abdi, M.2    Ahmadi, A.3    Wahedi, M.S.4    Menbari, S.5    Lahoopour, F.6    Rahbari, R.7
  • 111
    • 0038022609 scopus 로고    scopus 로고
    • Expression of genes for certain enzymes of pyrimidine and purine salvage pathway in peripherals blood leukocytes collected from patients with Graves' or Hashimoto's disease
    • Karbownik M, Brzezianska E, Zasada K, Lewinski A. Expression of genes for certain enzymes of pyrimidine and purine salvage pathway in peripherals blood leukocytes collected from patients with Graves' or Hashimoto's disease. J Cell Biochem 2003;89:550-555.
    • (2003) J Cell Biochem , vol.89 , pp. 550-555
    • Karbownik, M.1    Brzezianska, E.2    Zasada, K.3    Lewinski, A.4
  • 112
    • 79955808788 scopus 로고    scopus 로고
    • Diagnostic importance of adenosine deaminase activity for progression and invasion of human colon tumours
    • Kociel G, Stanojevic G, Nagomi A, Brankovic B, Pavlovicl D. Diagnostic importance of adenosine deaminase activity for progression and invasion of human colon tumours. Med Biol 2003;10:76-78.
    • (2003) Med Biol , vol.10 , pp. 76-78
    • Kociel, G.1    Stanojevic, G.2    Nagomi, A.3    Brankovic, B.4    Pavlovicl, D.5
  • 114
    • 79955829455 scopus 로고    scopus 로고
    • Adenosine deaminase in saliva as a diagnostic marker of squamous cell carcinoma of tongue
    • Rai B, Kaur J, Jacobs R, Arnand SC. Adenosine deaminase in saliva as a diagnostic marker of squamous cell carcinoma of tongue. Clin Oral Invest 2011;15:347-349.
    • (2011) Clin Oral Invest , vol.15 , pp. 347-349
    • Rai, B.1    Kaur, J.2    Jacobs, R.3    Arnand, S.C.4
  • 116
    • 84860824662 scopus 로고    scopus 로고
    • Plasma adenosine deaminase isoform 2 in cancer patients undergoing chemotherapy
    • Roberts EL, Roberts OT. Plasma adenosine deaminase isoform 2 in cancer patients undergoing chemotherapy. Br J Biomed Sci 2012;69:11-13.
    • (2012) Br J Biomed Sci , vol.69 , pp. 11-13
    • Roberts, E.L.1    Roberts, O.T.2
  • 119
    • 21644464835 scopus 로고    scopus 로고
    • Adenosine deaminase and 5' nucleotidase activities in peripheral blood T cells of multiple sclerosis patients
    • Vivekanandhan S, Soundararaian CC, Tripathi M, Maheshwari MC. Adenosine deaminase and 5' nucleotidase activities in peripheral blood T cells of multiple sclerosis patients. Neurochem Res 2005;30:453-456.
    • (2005) Neurochem Res , vol.30 , pp. 453-456
    • Vivekanandhan, S.1    Soundararaian, C.C.2    Tripathi, M.3    Maheshwari, M.C.4
  • 122
    • 80052672237 scopus 로고    scopus 로고
    • Cerebrospinal fluid C reactive protein and adenosine deaminase in meningitis in adults
    • Belagavi AC, Shalini M. Cerebrospinal fluid C reactive protein and adenosine deaminase in meningitis in adults. J Assoc Physicians India 2011;59:557-560.
    • (2011) J Assoc Physicians India , vol.59 , pp. 557-560
    • Belagavi, A.C.1    Shalini, M.2
  • 124
    • 33846148348 scopus 로고    scopus 로고
    • Adenosine deaminase, nitric oxide, superoxide dismutase and xanthine oxidase in patients with major depression: Impact of antidepressant treatment
    • Herken H, Gurel A, Selek S, Armutcu F, Ozen ME, Bulut M, Kap O, Yumru M, Savas HA, Akyol O. Adenosine deaminase, nitric oxide, superoxide dismutase and xanthine oxidase in patients with major depression: Impact of antidepressant treatment. Arch Med Res 2007;38:247-252.
    • (2007) Arch Med Res , vol.38 , pp. 247-252
    • Herken, H.1    Gurel, A.2    Selek, S.3    Armutcu, F.4    Ozen, M.E.5    Bulut, M.6    Kap, O.7    Yumru, M.8    Savas, H.A.9    Akyol, O.10
  • 125
    • 32044434640 scopus 로고    scopus 로고
    • Nitric oxide, adenosine deaminase, xanthine oxidase and superoxide dismutase in patients with panic disorder: Alterations by antidepressant treatment
    • Herken H, Akyol O, Yilmaz HR, Tutkun H, Savas HA, Ozen ME, Kalenderoglu A, Gulec M. Nitric oxide, adenosine deaminase, xanthine oxidase and superoxide dismutase in patients with panic disorder: Alterations by antidepressant treatment. Hum Psychopharmacol 2006;21:53-59.
    • (2006) Hum Psychopharmacol , vol.21 , pp. 53-59
    • Herken, H.1    Akyol, O.2    Yilmaz, H.R.3    Tutkun, H.4    Savas, H.A.5    Ozen, M.E.6    Kalenderoglu, A.7    Gulec, M.8
  • 126
    • 84867689709 scopus 로고    scopus 로고
    • Comparison of superoxide dismutase, glutathione peroxidase and adenosine deaminase activities between respiratory and nocturnal subtypes of patients with panic disorder
    • Ozdemir O, Selvi Y, Ozkol H, Tuluce Y, Besiroglu L, Aydin A. Comparison of superoxide dismutase, glutathione peroxidase and adenosine deaminase activities between respiratory and nocturnal subtypes of patients with panic disorder. Neuropsychobiology 2012;66:244-251.
    • (2012) Neuropsychobiology , vol.66 , pp. 244-251
    • Ozdemir, O.1    Selvi, Y.2    Ozkol, H.3    Tuluce, Y.4    Besiroglu, L.5    Aydin, A.6
  • 128
    • 59449091811 scopus 로고    scopus 로고
    • Primary immunodeficiency diseases
    • In: Ochs HD, Smith CIE, Puck JM, Eds.Oxford, UK: Oxford University Press.
    • Hirschhorn R, Candotti F. Primary immunodeficiency diseases. In: Ochs HD, Smith CIE, Puck JM, Eds. Immunodeficiency due to Defects on Purine Metabolism. Oxford, UK: Oxford University Press; 2006. p 169-196.
    • (2006) Immunodeficiency due to Defects on Purine Metabolism , pp. 169-196
    • Hirschhorn, R.1    Candotti, F.2
  • 129
    • 77953018306 scopus 로고    scopus 로고
    • Bone marrow transplantation and alternatives for adenosine deaminase deficiency
    • Gaspar HB. Bone marrow transplantation and alternatives for adenosine deaminase deficiency. Immunol Allergy Clin N Am 2010;30:221-236.
    • (2010) Immunol Allergy Clin N Am , vol.30 , pp. 221-236
    • Gaspar, H.B.1
  • 130
    • 0141853011 scopus 로고    scopus 로고
    • Genotype is an important determinant of phenotype in adenosine deaminase deficiency
    • Hershfield MS. Genotype is an important determinant of phenotype in adenosine deaminase deficiency. Curr Opin Immunol 2003;15:571-577.
    • (2003) Curr Opin Immunol , vol.15 , pp. 571-577
    • Hershfield, M.S.1
  • 132
    • 0030837064 scopus 로고    scopus 로고
    • SCID: The role of adenosine deaminase deficiency
    • Resta T, Thompson LF. SCID: The role of adenosine deaminase deficiency. Immunol Today 1997;18:371-374.
    • (1997) Immunol Today , vol.18 , pp. 371-374
    • Resta, T.1    Thompson, L.F.2
  • 134
    • 12344281073 scopus 로고    scopus 로고
    • New insights into adenosine-receptor-mediated immunosuppression and the role of adenosine in causing the immunodeficiency associated with adenosine deaminase deficiency
    • Hershfield MS. New insights into adenosine-receptor-mediated immunosuppression and the role of adenosine in causing the immunodeficiency associated with adenosine deaminase deficiency. Eur J Immunol 2005;35:25-30.
    • (2005) Eur J Immunol , vol.35 , pp. 25-30
    • Hershfield, M.S.1
  • 136
    • 0021888349 scopus 로고
    • Pathologic findings in adenosine deaminase-deficient severe combined immunodeficiency. I. Kidney, adrenal and chodro-osseus tissue alterations
    • Ratech H, Greco MA, Gallo G, Rimoin DL, Kamino H, Hirschhorn R. Pathologic findings in adenosine deaminase-deficient severe combined immunodeficiency. I. Kidney, adrenal and chodro-osseus tissue alterations. Am J Pathol 1985;120:157-169.
    • (1985) Am J Pathol , vol.120 , pp. 157-169
    • Ratech, H.1    Greco, M.A.2    Gallo, G.3    Rimoin, D.L.4    Kamino, H.5    Hirschhorn, R.6
  • 138
    • 0034968336 scopus 로고    scopus 로고
    • Cognitive and behavioural abnormalities in adenosine deaminase deficient severe combined immunodeficiency
    • Rogers MH, Lwin R, Fairbanks L, Gerritsen B, Gaspar HB. Cognitive and behavioural abnormalities in adenosine deaminase deficient severe combined immunodeficiency. J Pediatr 2001;139:44-50.
    • (2001) J Pediatr , vol.139 , pp. 44-50
    • Rogers, M.H.1    Lwin, R.2    Fairbanks, L.3    Gerritsen, B.4    Gaspar, H.B.5
  • 142
    • 78649451337 scopus 로고    scopus 로고
    • The different extent of B and T cell immune reconstitution after hematopoietic stem cell transplantation and enzyme replacement therapies in SCID patients with adenosine deaminase deficiency
    • Serana F, Sottini A, Chiarini M, Zanotti C, Ghidini C, Lanfranchi A, Notarangelo LD, Caimi L, Imberti L. The different extent of B and T cell immune reconstitution after hematopoietic stem cell transplantation and enzyme replacement therapies in SCID patients with adenosine deaminase deficiency. J Immunol 2010;185:7713-7722.
    • (2010) J Immunol , vol.185 , pp. 7713-7722
    • Serana, F.1    Sottini, A.2    Chiarini, M.3    Zanotti, C.4    Ghidini, C.5    Lanfranchi, A.6    Notarangelo, L.D.7    Caimi, L.8    Imberti, L.9
  • 143
    • 84867745449 scopus 로고    scopus 로고
    • Outcome of hematopoietic stem cell transplantation for adenosine deaminase-deficient severe combined immunodeficiency
    • Hassan A, Booth C, Brightwell A, Allwood Z, Veys P, Rao K. Outcome of hematopoietic stem cell transplantation for adenosine deaminase-deficient severe combined immunodeficiency. Blood 2012;120:3615-3624.
    • (2012) Blood , vol.120 , pp. 3615-3624
    • Hassan, A.1    Booth, C.2    Brightwell, A.3    Allwood, Z.4    Veys, P.5    Rao, K.6
  • 144
    • 26044474889 scopus 로고    scopus 로고
    • Long-term efficacy of enzyme replacement therapy for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID)
    • Chan B, Wara, D, Bastian J, Hershfield MS, Bohnscak J, Azen CG, Parkman R, Weinberg K, Kohn DB. Long-term efficacy of enzyme replacement therapy for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID). Clin Immunol 2005;117:133-143.
    • (2005) Clin Immunol , vol.117 , pp. 133-143
    • Chan, B.1    Wara, D.2    Bastian, J.3    Hershfield, M.S.4    Bohnscak, J.5    Azen, C.G.6    Parkman, R.7    Weinberg, K.8    Kohn, D.B.9
  • 146
    • 84868576992 scopus 로고    scopus 로고
    • Gene therapy for ADA-SCID. Defining the factors for successful outcome
    • Gaspar HB. Gene therapy for ADA-SCID. Defining the factors for successful outcome. Blood 2012;120:3628-3629.
    • (2012) Blood , vol.120 , pp. 3628-3629
    • Gaspar, H.B.1
  • 147
    • 78449233751 scopus 로고    scopus 로고
    • Update on gene therapy for adenosine deaminase-deficient severe combined immunodeficiency
    • Ferrua F, Brigida I, Aiuti A. Update on gene therapy for adenosine deaminase-deficient severe combined immunodeficiency. Curr Opin Allergy Clin Immunol 2010;10:551-556.
    • (2010) Curr Opin Allergy Clin Immunol , vol.10 , pp. 551-556
    • Ferrua, F.1    Brigida, I.2    Aiuti, A.3
  • 149
    • 84868589740 scopus 로고    scopus 로고
    • Gene therapy for adenosine deaminase-deficient severe combined immune deficiency. Clinical comparison of retroviral vectors and treatment plans
    • Candotti F, Shaw KL, Muul L, Carbonaro D, Sokolic R, Choi C. Gene therapy for adenosine deaminase-deficient severe combined immune deficiency. Clinical comparison of retroviral vectors and treatment plans. Blood 2012;120:3635-3646.
    • (2012) Blood , vol.120 , pp. 3635-3646
    • Candotti, F.1    Shaw, K.L.2    Muul, L.3    Carbonaro, D.4    Sokolic, R.5    Choi, C.6
  • 151
    • 84858308338 scopus 로고    scopus 로고
    • Gene therapy for severe combined immunodeficiency due to adenosine deaminase deficiency
    • Montiel-Equihua CA, Thrasher AJ, Gaspar HB. Gene therapy for severe combined immunodeficiency due to adenosine deaminase deficiency. Curr Gene Ther 2012;12:57-65.
    • (2012) Curr Gene Ther , vol.12 , pp. 57-65
    • Montiel-Equihua, C.A.1    Thrasher, A.J.2    Gaspar, H.B.3
  • 152
    • 84861833417 scopus 로고    scopus 로고
    • Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapy
    • Sauer AV, Morbach H, Brigida I, Ng YS, Aiuti A, Meffre E. Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapy. J Clin Invest 2012;122:2141-2152.
    • (2012) J Clin Invest , vol.122 , pp. 2141-2152
    • Sauer, A.V.1    Morbach, H.2    Brigida, I.3    Ng, Y.S.4    Aiuti, A.5    Meffre, E.6
  • 153
    • 84879884476 scopus 로고    scopus 로고
    • Gene therapy of primary T cell immunodeficiencies
    • Fischer A, Hacein-Bey-Abina S, Cavazzana-Calvo M. Gene therapy of primary T cell immunodeficiencies. Gene 2013;525:170-173.
    • (2013) Gene , vol.525 , pp. 170-173
    • Fischer, A.1    Hacein-Bey-Abina, S.2    Cavazzana-Calvo, M.3
  • 154
    • 0347129832 scopus 로고    scopus 로고
    • A highly potent non-nucleoside adenosine deaminase inhibitor: Efficient drug discovery by intentional lead hybridization
    • Terasaka T, Kinoshita T, Kuno M, Nakanishi I. A highly potent non-nucleoside adenosine deaminase inhibitor: Efficient drug discovery by intentional lead hybridization. J Am Chem Soc 2004;126:34-35.
    • (2004) J Am Chem Soc , vol.126 , pp. 34-35
    • Terasaka, T.1    Kinoshita, T.2    Kuno, M.3    Nakanishi, I.4
  • 156
    • 3142654156 scopus 로고    scopus 로고
    • Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors
    • Terasaka T, Kinoshita T, Kuno M, Seki N, Tanaka K, Nakanishi I. Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors. J Med Chem 2004;47:3730-3743.
    • (2004) J Med Chem , vol.47 , pp. 3730-3743
    • Terasaka, T.1    Kinoshita, T.2    Kuno, M.3    Seki, N.4    Tanaka, K.5    Nakanishi, I.6
  • 157
    • 23444440510 scopus 로고    scopus 로고
    • Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modelling studies
    • Da
    • Da Settimo F, Primofiore G, La Motta C, Taliani S, Simorini F, Marini AM, Mugnaini L, Lavecchia A, Novellino E, Tuscano D, Martini C. Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3, 4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modelling studies. J Med Chem 2005;48:5162-5174.
    • (2005) J Med Chem , vol.48 , pp. 5162-5174
    • Settimo, F.1    Primofiore, G.2    La Motta, C.3    Taliani, S.4    Simorini, F.5    Marini, A.M.6    Mugnaini, L.7    Lavecchia, A.8    Novellino, E.9    Tuscano, D.10    Martini, C.11
  • 158
    • 22744453821 scopus 로고    scopus 로고
    • Rational design of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors: Predicting enzyme conformational change and metabolism
    • Terasaka T, Tsuji K, Kato T, Nakanishi I, Kinoshita T, Kato Y, Kuno M, Inoue T, Tanaka K, Nakamura K. Rational design of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors: Predicting enzyme conformational change and metabolism. J Med Chem 2005;48:4750-4753.
    • (2005) J Med Chem , vol.48 , pp. 4750-4753
    • Terasaka, T.1    Tsuji, K.2    Kato, T.3    Nakanishi, I.4    Kinoshita, T.5    Kato, Y.6    Kuno, M.7    Inoue, T.8    Tanaka, K.9    Nakamura, K.10
  • 159
    • 39149102521 scopus 로고    scopus 로고
    • Inhibition of adenosine deaminase by analogues of adenosine and inosine, incorporating a common hetercyclic base, 4(7)-amino-6(5)H-imidazol[4,5-d]pyridazin-7(4)one
    • Ujjinamatada RK, Phatak P, Burger AM, Hosmane RS. Inhibition of adenosine deaminase by analogues of adenosine and inosine, incorporating a common hetercyclic base, 4(7)-amino-6(5)H-imidazol[4, 5-d]pyridazin-7(4)one. J Med Chem 2008;51:694-698.
    • (2008) J Med Chem , vol.51 , pp. 694-698
    • Ujjinamatada, R.K.1    Phatak, P.2    Burger, A.M.3    Hosmane, R.S.4
  • 161
    • 78651112696 scopus 로고    scopus 로고
    • Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors
    • Gillerman I, Fischer B. Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors. J Med Chem 2011;54:107-121.
    • (2011) J Med Chem , vol.54 , pp. 107-121
    • Gillerman, I.1    Fischer, B.2
  • 163
    • 0037344916 scopus 로고    scopus 로고
    • Purine nucleoside analogues in the treatment of myeloid leukemias
    • Robak T. Purine nucleoside analogues in the treatment of myeloid leukemias. Leuk Lymphoma 2003;44:391-409.
    • (2003) Leuk Lymphoma , vol.44 , pp. 391-409
    • Robak, T.1
  • 164
    • 33645010937 scopus 로고    scopus 로고
    • Role of single-agent purine analogues in therapy of peripheral T-cell lymphomas
    • Dearden CE. Role of single-agent purine analogues in therapy of peripheral T-cell lymphomas. Semin Hematol 2006;43:S22-S26.
    • (2006) Semin Hematol , vol.43 , pp. S22-S26
    • Dearden, C.E.1
  • 167
    • 0037323255 scopus 로고    scopus 로고
    • Structure of bovine adenosine deaminase complexed with 6-hydroxy-1,6-dihydropurine riboside
    • Kinoshita T, Nishio N, Nakanishi I, Sato A, Fujii T. Structure of bovine adenosine deaminase complexed with 6-hydroxy-1, 6-dihydropurine riboside. Acta Crystallogr 2003;D59:299-303.
    • (2003) Acta Crystallogr , vol.59 D , pp. 299-303
    • Kinoshita, T.1    Nishio, N.2    Nakanishi, I.3    Sato, A.4    Fujii, T.5
  • 168
    • 34347227434 scopus 로고    scopus 로고
    • Transition-state variation in human, bovine and Plasmodium falciparum adenosine deaminases
    • Luo M, Singh V, Taylor EA, Schramm VL. Transition-state variation in human, bovine and Plasmodium falciparum adenosine deaminases. J Am Chem Soc 2007;129:8008-8017.
    • (2007) J Am Chem Soc , vol.129 , pp. 8008-8017
    • Luo, M.1    Singh, V.2    Taylor, E.A.3    Schramm, V.L.4
  • 169
    • 79957533062 scopus 로고    scopus 로고
    • Hairy cell leukemia: A successful model for experimental therapeutics-Pentostatin and new ideas
    • Grever MR. Hairy cell leukemia: A successful model for experimental therapeutics-Pentostatin and new ideas. Leuk Lymphoma 2011;52:25-28.
    • (2011) Leuk Lymphoma , vol.52 , pp. 25-28
    • Grever, M.R.1
  • 170
    • 79957465550 scopus 로고    scopus 로고
    • Mechanism of action of pentostatin and cladribine in hairy cell leukemia
    • Johnston JB. Mechanism of action of pentostatin and cladribine in hairy cell leukemia. Leuk Lymphoma 2011; 52:43-45.
    • (2011) Leuk Lymphoma , vol.52 , pp. 43-45
    • Johnston, J.B.1
  • 171
    • 35348875468 scopus 로고    scopus 로고
    • Adenosine and cardioprotection in chronic heart failure: Genes and protein expression
    • Hisatome I. Adenosine and cardioprotection in chronic heart failure: Genes and protein expression. Hypertens Res 2007;30:757-758.
    • (2007) Hypertens Res , vol.30 , pp. 757-758
    • Hisatome, I.1
  • 172
    • 84862596156 scopus 로고    scopus 로고
    • Myocardial protection in beating heart cardiac surgery: I-Pre- or postconditioning with inhibition of es-ENT1 nucleoside transporter and adenosine deaminase attenuates post-MI reperfusion-mediated ventricular fibrillation and regional contractile dysfunction
    • Abd-Elfattah AS, Aly H, Hanan S, Wechsler AS. Myocardial protection in beating heart cardiac surgery: I-Pre- or postconditioning with inhibition of es-ENT1 nucleoside transporter and adenosine deaminase attenuates post-MI reperfusion-mediated ventricular fibrillation and regional contractile dysfunction. J Thorac Cardiovasc Surg 2012;144:250-255.
    • (2012) J Thorac Cardiovasc Surg , vol.144 , pp. 250-255
    • Abd-Elfattah, A.S.1    Aly, H.2    Hanan, S.3    Wechsler, A.S.4
  • 173
    • 0038581255 scopus 로고    scopus 로고
    • Therapeutic potencial for transient inhibition of adenosine deaminase in systemic inflammatory response syndrome
    • Law WR, Valli VE, Conlon BA. Therapeutic potencial for transient inhibition of adenosine deaminase in systemic inflammatory response syndrome. Crit Care Med 2003;31:1475-1481.
    • (2003) Crit Care Med , vol.31 , pp. 1475-1481
    • Law, W.R.1    Valli, V.E.2    Conlon, B.A.3
  • 174
    • 56349099258 scopus 로고    scopus 로고
    • The adenosine deaminase inhibitor erytro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: A prospective, randomised laboratory investigation
    • Kayhan N, Funke B, Conzelmann NO, Winkler H, Hofer S, Steppan J, Schmidt H, Bardenheuer H, Vahl CF, Weigand MA. The adenosine deaminase inhibitor erytro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: A prospective, randomised laboratory investigation. Crit Care 2008;12:R125-R135.
    • (2008) Crit Care , vol.12 , pp. R125-R135
    • Kayhan, N.1    Funke, B.2    Conzelmann, N.O.3    Winkler, H.4    Hofer, S.5    Steppan, J.6    Schmidt, H.7    Bardenheuer, H.8    Vahl, C.F.9    Weigand, M.A.10
  • 175
  • 176
    • 0027398949 scopus 로고
    • A pre-transition-state mimic of an enzyme: X-ray structure of adenosine deaminase with bound 1-deazaadenosine and zinc-activated water
    • Wilson DK, Quiocho FA. A pre-transition-state mimic of an enzyme: X-ray structure of adenosine deaminase with bound 1-deazaadenosine and zinc-activated water. Biochemistry 1993;32:1689-1694.
    • (1993) Biochemistry , vol.32 , pp. 1689-1694
    • Wilson, D.K.1    Quiocho, F.A.2
  • 177
    • 0032499630 scopus 로고    scopus 로고
    • Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity
    • Wang Z, Quiocho FA. Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity. Biochemistry 1998;37:8314-8324.
    • (1998) Biochemistry , vol.37 , pp. 8314-8324
    • Wang, Z.1    Quiocho, F.A.2
  • 178
    • 45849138147 scopus 로고    scopus 로고
    • Conformational change of adenosine deaminase during ligand-exchange in a crystal
    • Kinoshita T, Tada T, Nakanishi I. Conformational change of adenosine deaminase during ligand-exchange in a crystal. Biochem Biophys Res Commun 2008;373:53-57.
    • (2008) Biochem Biophys Res Commun , vol.373 , pp. 53-57
    • Kinoshita, T.1    Tada, T.2    Nakanishi, I.3
  • 179
    • 0026434561 scopus 로고
    • Atomic structure of adenosine deaminase complexed with a transition-state analog: Understanding catalysis and immunodeficiency mutations
    • Wilson DK, Rudolph FB, Quiocho FA. Atomic structure of adenosine deaminase complexed with a transition-state analog: Understanding catalysis and immunodeficiency mutations. Science 1991;252:1278-1284.
    • (1991) Science , vol.252 , pp. 1278-1284
    • Wilson, D.K.1    Rudolph, F.B.2    Quiocho, F.A.3
  • 183
    • 0026444022 scopus 로고
    • Refined 2.5A structure of murine adenosine deaminase at pH 6.0
    • Sharff AJ, Wilson DK, Chang Z, Quiocho FA. Refined 2.5A structure of murine adenosine deaminase at pH 6.0. J Mol Biol 1992;226:917-921.
    • (1992) J Mol Biol , vol.226 , pp. 917-921
    • Sharff, A.J.1    Wilson, D.K.2    Chang, Z.3    Quiocho, F.A.4
  • 186
    • 84872681105 scopus 로고    scopus 로고
    • Unveiling the binding mode of adenosine deaminase inhibitors to the active site of the enzyme: Implication for rational drug design
    • Trincavelli ML. Unveiling the binding mode of adenosine deaminase inhibitors to the active site of the enzyme: Implication for rational drug design. Purinergic Signal 2013;9:1-3.
    • (2013) Purinergic Signal , vol.9 , pp. 1-3
    • Trincavelli, M.L.1
  • 187
    • 0022497287 scopus 로고
    • Transition-state stabilization by adenosine deaminase: Structural studies of its inhibitory complex with deoxycoformycin
    • Frick L, Wolfenden R, Smal E, Baker DC. Transition-state stabilization by adenosine deaminase: Structural studies of its inhibitory complex with deoxycoformycin. Biochemistry 1986;25:1616-1621.
    • (1986) Biochemistry , vol.25 , pp. 1616-1621
    • Frick, L.1    Wolfenden, R.2    Smal, E.3    Baker, D.C.4
  • 188
    • 0026499905 scopus 로고
    • The rate of formation of transition-state analogues in the active site of adenosine deaminase is encounter-controlled: Implications for the mechanism
    • Kurz LC, Moix L, Riley MC, Frieden C. The rate of formation of transition-state analogues in the active site of adenosine deaminase is encounter-controlled: Implications for the mechanism. Biochemistry 1992;31:39-48.
    • (1992) Biochemistry , vol.31 , pp. 39-48
    • Kurz, L.C.1    Moix, L.2    Riley, M.C.3    Frieden, C.4
  • 189
    • 0016852319 scopus 로고
    • Adenosine deaminase from human erythrocytes: Purification and effects of adenosine analogs
    • Agarwal RP, Sagar SM, Parks RE Jr. Adenosine deaminase from human erythrocytes: Purification and effects of adenosine analogs. Biochem Pharmacol 1975;24:693-701.
    • (1975) Biochem Pharmacol , vol.24 , pp. 693-701
    • Agarwal, R.P.1    Sagar, S.M.2    Parks Jr, R.E.3
  • 190
    • 0010049696 scopus 로고
    • Substrate specificity of adenosine deaminase-Function of the 5'-hydroxyl group of adenosine
    • Nair V, Wiechert RJ. Substrate specificity of adenosine deaminase-Function of the 5'-hydroxyl group of adenosine. Bioorg Chem 1980;9:423-433.
    • (1980) Bioorg Chem , vol.9 , pp. 423-433
    • Nair, V.1    Wiechert, R.J.2
  • 191
    • 0019414866 scopus 로고
    • Substrate specificity of adenosine deaminase: The role of the substituents at the 2'- and 3'-carbons of adenine nucleosides, of their configuration and of the conformation of the furanose ring
    • Mikhailopoulo IA, Wiedner H, Cramer F. Substrate specificity of adenosine deaminase: The role of the substituents at the 2'- and 3'-carbons of adenine nucleosides, of their configuration and of the conformation of the furanose ring. Biochem Pharmacol 1981;30:1001-1004.
    • (1981) Biochem Pharmacol , vol.30 , pp. 1001-1004
    • Mikhailopoulo, I.A.1    Wiedner, H.2    Cramer, F.3
  • 192
    • 0027510355 scopus 로고
    • Alternative substrates for calf intestinal adenosine deaminase. A pre-steady-state kinetic analysis
    • Porter DJ, Spector T. Alternative substrates for calf intestinal adenosine deaminase. A pre-steady-state kinetic analysis. J Biol Chem 1993;268:2480-2485.
    • (1993) J Biol Chem , vol.268 , pp. 2480-2485
    • Porter, D.J.1    Spector, T.2
  • 193
  • 194
    • 0036908425 scopus 로고    scopus 로고
    • The stability curve of bovine adenosine deaminase is bimodal
    • Anderson E, Britt BM. The stability curve of bovine adenosine deaminase is bimodal. J Biomol Struct Dyn 2002;20:375-380.
    • (2002) J Biomol Struct Dyn , vol.20 , pp. 375-380
    • Anderson, E.1    Britt, B.M.2
  • 195
    • 1042288303 scopus 로고    scopus 로고
    • Urea-dependent unfolding of murine adenosine deaminase: Sequential destabilization as measured by 19F NMR
    • Shu Q, Frieden C. Urea-dependent unfolding of murine adenosine deaminase: Sequential destabilization as measured by 19F NMR. Biochemistry 2004;43:1432-1439.
    • (2004) Biochemistry , vol.43 , pp. 1432-1439
    • Shu, Q.1    Frieden, C.2
  • 196
    • 9644284454 scopus 로고    scopus 로고
    • Relation of enzyme activity to local/global stability of murine adenosine deaminase: 19F NMR studies
    • Shu Q, Frieden C. Relation of enzyme activity to local/global stability of murine adenosine deaminase: 19F NMR studies. J Mol Biol 2005;345:599-610.
    • (2005) J Mol Biol , vol.345 , pp. 599-610
    • Shu, Q.1    Frieden, C.2
  • 198
    • 0021416988 scopus 로고
    • Progress curve analysis of adenosine deaminase-catalyzed reactions
    • Spector T. Progress curve analysis of adenosine deaminase-catalyzed reactions. Anal Biochem 1984;138:242-245.
    • (1984) Anal Biochem , vol.138 , pp. 242-245
    • Spector, T.1
  • 199
    • 0023747841 scopus 로고
    • Bovine skeletal muscle adenosine deaminase: Kinetic and thermodynamic studies
    • Martínez C, Zumalacárregui JM, Díez V. Bovine skeletal muscle adenosine deaminase: Kinetic and thermodynamic studies. Enzyme 1988;39:199-204.
    • (1988) Enzyme , vol.39 , pp. 199-204
    • Martínez, C.1    Zumalacárregui, J.M.2    Díez, V.3
  • 200
    • 0024340596 scopus 로고
    • Adenosine deaminase activity of chicken erythrocyte and heart cytosols
    • Spivey DB, Snow LD. Adenosine deaminase activity of chicken erythrocyte and heart cytosols. Int J Biochem 1989;21:645-648.
    • (1989) Int J Biochem , vol.21 , pp. 645-648
    • Spivey, D.B.1    Snow, L.D.2
  • 201
    • 0026092236 scopus 로고
    • Fitting integrated enzyme rate equations to progress curves with the use of a weighting matrix
    • Franco R, Aran JM, Canela EI. Fitting integrated enzyme rate equations to progress curves with the use of a weighting matrix. Biochem J 1991;274:509-511.
    • (1991) Biochem J , vol.274 , pp. 509-511
    • Franco, R.1    Aran, J.M.2    Canela, E.I.3
  • 203
    • 79955688065 scopus 로고    scopus 로고
    • Studies on the adenosine deaminase-catalyzed conversion of adenosine and nucleoside prodrugs by different capillary electrophoresis modes
    • Pei L, Xie L, Lin Q, Ling X, Guan Z, Yang Z. Studies on the adenosine deaminase-catalyzed conversion of adenosine and nucleoside prodrugs by different capillary electrophoresis modes. Anal Biochem 2011;414:131-1370.
    • (2011) Anal Biochem , vol.414 , pp. 131-1370
    • Pei, L.1    Xie, L.2    Lin, Q.3    Ling, X.4    Guan, Z.5    Yang, Z.6
  • 204
    • 0020375548 scopus 로고
    • Inhibitors of adenosine deaminase
    • Agarwal RP. Inhibitors of adenosine deaminase. Pharmacol Ther 1982;17:399-429.
    • (1982) Pharmacol Ther , vol.17 , pp. 399-429
    • Agarwal, R.P.1
  • 205
    • 62249088308 scopus 로고
    • Inhibition of adenosine deaminase from several sources by deaza derivatives of adenosine and EHNA
    • Lupidi G, Cristalli G, Marmocchi F, Riva F, Grifantini M. Inhibition of adenosine deaminase from several sources by deaza derivatives of adenosine and EHNA. J Enzyme Inhib 1985;1:67-75.
    • (1985) J Enzyme Inhib , vol.1 , pp. 67-75
    • Lupidi, G.1    Cristalli, G.2    Marmocchi, F.3    Riva, F.4    Grifantini, M.5
  • 206
    • 0023840331 scopus 로고
    • Purification and partial characterization of brain adenosine deaminase: Inhibition by purine compounds and by drugs
    • Centelles JJ, Franco R Bozal J. Purification and partial characterization of brain adenosine deaminase: Inhibition by purine compounds and by drugs. J Neurosci Res 1988;19:258-267.
    • (1988) J Neurosci Res , vol.19 , pp. 258-267
    • Centelles, J.J.1    Franco, R.2    Bozal, J.3
  • 207
    • 0038199705 scopus 로고    scopus 로고
    • Purification and characterization of intestinal adenosine deaminase from mice
    • Singh LS, Sharma R. Purification and characterization of intestinal adenosine deaminase from mice. Mol Cell Biochem 2000;204:127-134.
    • (2000) Mol Cell Biochem , vol.204 , pp. 127-134
    • Singh, L.S.1    Sharma, R.2
  • 208
    • 0034850277 scopus 로고    scopus 로고
    • Binding thermodynamics of the transition state analogue coformycin and of the ground state analogue 1-deazaadenosine to bovine adenosine deaminase
    • Castro C, Britt BM. Binding thermodynamics of the transition state analogue coformycin and of the ground state analogue 1-deazaadenosine to bovine adenosine deaminase. J Enzyme Inhib 2001;16:217-232.
    • (2001) J Enzyme Inhib , vol.16 , pp. 217-232
    • Castro, C.1    Britt, B.M.2
  • 209
    • 0036887567 scopus 로고    scopus 로고
    • Purification and characterization of adenosine deaminase from camel skeletal muscle
    • Alrokayan S. Purification and characterization of adenosine deaminase from camel skeletal muscle. Int J Biochem Cell Biol 2002;34:1608-1618.
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1608-1618
    • Alrokayan, S.1
  • 210
    • 42749086791 scopus 로고    scopus 로고
    • Fasciola gigantica: Purification and characterization of adenosine deaminase
    • Ali EM. Fasciola gigantica: Purification and characterization of adenosine deaminase. Exp Parasitol 2008;119:285-290.
    • (2008) Exp Parasitol , vol.119 , pp. 285-290
    • Ali, E.M.1
  • 211
    • 79958768254 scopus 로고    scopus 로고
    • Adenosine deaminase from Streptomyces coelicolor: Recombinant expression, purification and characterization
    • Pornbanlualap S, Chalopagorn P. Adenosine deaminase from Streptomyces coelicolor: Recombinant expression, purification and characterization. Protein Expr Purif 2011;78:167-173.
    • (2011) Protein Expr Purif , vol.78 , pp. 167-173
    • Pornbanlualap, S.1    Chalopagorn, P.2
  • 212
    • 84859791287 scopus 로고    scopus 로고
    • The adenosine deaminases from Plasmodium vivax and Plasmodium falciparum exhibit surprising differences in ligand specificity
    • Ivanov A, Matsumura I. The adenosine deaminases from Plasmodium vivax and Plasmodium falciparum exhibit surprising differences in ligand specificity. J Mol Graph Model 2012;35:43-48.
    • (2012) J Mol Graph Model , vol.35 , pp. 43-48
    • Ivanov, A.1    Matsumura, I.2
  • 215
    • 34249808801 scopus 로고    scopus 로고
    • Synthesis of 5'-methylthio coformycins: Specific inhibitors for malarial adenosine deaminase
    • Tyler PC, Taylor EA, Fröhlich RF, Schramm VL. Synthesis of 5'-methylthio coformycins: Specific inhibitors for malarial adenosine deaminase. J Am Chem Soc 2007;129:6872-6879.
    • (2007) J Am Chem Soc , vol.129 , pp. 6872-6879
    • Tyler, P.C.1    Taylor, E.A.2    Fröhlich, R.F.3    Schramm, V.L.4
  • 216
    • 0028519052 scopus 로고
    • Crystallographic observation of a trapped tetrahedral intermediate in a metalloenzyme
    • Wilson DK, Quiocho FA. Crystallographic observation of a trapped tetrahedral intermediate in a metalloenzyme. Nat Struct Biol 1994;1:691-694.
    • (1994) Nat Struct Biol , vol.1 , pp. 691-694
    • Wilson, D.K.1    Quiocho, F.A.2
  • 217
    • 0027456581 scopus 로고
    • Mutational analysis of active site residues of human adenosine deaminase
    • Bhaumik D, Medin J, Gathy K, Coleman MS. Mutational analysis of active site residues of human adenosine deaminase. J Biol Chem 1993;268:5464-5470.
    • (1993) J Biol Chem , vol.268 , pp. 5464-5470
    • Bhaumik, D.1    Medin, J.2    Gathy, K.3    Coleman, M.S.4
  • 218
    • 0030038183 scopus 로고    scopus 로고
    • Site-directed mutagenesis of active site glutamate-217 in mouse adenosine deaminase
    • Mohamedali KA, Kurz LC, Rudolph FB. Site-directed mutagenesis of active site glutamate-217 in mouse adenosine deaminase. Biochemistry 1996;35:1672-1680.
    • (1996) Biochemistry , vol.35 , pp. 1672-1680
    • Mohamedali, K.A.1    Kurz, L.C.2    Rudolph, F.B.3
  • 219
    • 0030459608 scopus 로고    scopus 로고
    • Site-directed mutagenesis of histidine 238 in mouse adenosine deaminase: Substitution of histidine 238 does not impede hydroxylate formation
    • Sideraki V, Wilson DK, Kurz LC, Quiocho FA, Rudolph FB. Site-directed mutagenesis of histidine 238 in mouse adenosine deaminase: Substitution of histidine 238 does not impede hydroxylate formation. Biochemistry 1996;35:15019-15028.
    • (1996) Biochemistry , vol.35 , pp. 15019-15028
    • Sideraki, V.1    Wilson, D.K.2    Kurz, L.C.3    Quiocho, F.A.4    Rudolph, F.B.5
  • 221
    • 0041733948 scopus 로고    scopus 로고
    • Prediction of the potency of inhibitors of adenosine deaminase by QM/MM calculations
    • Gleeson MP, Burton NA Hillier IH. Prediction of the potency of inhibitors of adenosine deaminase by QM/MM calculations. Chem Commun 2003;17:280-281.
    • (2003) Chem Commun , vol.17 , pp. 280-281
    • Gleeson, M.P.1    Burton, N.A.2    Hillier, I.H.3
  • 222
    • 77956256272 scopus 로고    scopus 로고
    • A theoretical study on the catalytic mechanism of Mus musculus adenosine deaminase
    • Wu XH, Zou GL, Quan, JM, Wu YD. A theoretical study on the catalytic mechanism of Mus musculus adenosine deaminase. J Comput Chem 2010;31:2238-2247.
    • (2010) J Comput Chem , vol.31 , pp. 2238-2247
    • Wu, X.H.1    Zou, G.L.2    Quan, J.M.3    Wu, Y.D.4
  • 223
    • 0022589903 scopus 로고
    • Heterogeneous localization of some purine enzymes in subcellular fractions of rat brain and cerebellum
    • Franco R, Canela EI, Bozal J. Heterogeneous localization of some purine enzymes in subcellular fractions of rat brain and cerebellum. Neurochem Res 1986;11:423-435.
    • (1986) Neurochem Res , vol.11 , pp. 423-435
    • Franco, R.1    Canela, E.I.2    Bozal, J.3
  • 224
    • 0031908810 scopus 로고    scopus 로고
    • Enzymatic and extraenzymatic role of ecto-adenosine deaminase in lymphocytes
    • Franco R, Valenzuela A, Lluís C, Blanco J. Enzymatic and extraenzymatic role of ecto-adenosine deaminase in lymphocytes. Immunol Rev 1998;161:27-42.
    • (1998) Immunol Rev , vol.161 , pp. 27-42
    • Franco, R.1    Valenzuela, A.2    Lluís, C.3    Blanco, J.4
  • 225
    • 0036798380 scopus 로고    scopus 로고
    • The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells
    • Yegutkin GG, Henttinen T, Samburski SS, Spychala J, Jalkanen S. The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells. Biochem J 2002;367:121-128.
    • (2002) Biochem J , vol.367 , pp. 121-128
    • Yegutkin, G.G.1    Henttinen, T.2    Samburski, S.S.3    Spychala, J.4    Jalkanen, S.5
  • 226
    • 13444262230 scopus 로고    scopus 로고
    • Adenosine deaminase deficiency: Metabolic basis of immune deficiency and pulmonary inflammation
    • Blackburn MD, Kellems RE. Adenosine deaminase deficiency: Metabolic basis of immune deficiency and pulmonary inflammation. Adv Immunol 2005;86:1-41.
    • (2005) Adv Immunol , vol.86 , pp. 1-41
    • Blackburn, M.D.1    Kellems, R.E.2
  • 227
    • 0024591683 scopus 로고
    • Ecto-enzyme activity of human erythrocyte adenosine deaminase
    • Bielat K, Tritsch GL. Ecto-enzyme activity of human erythrocyte adenosine deaminase. Mol Cell Biochem 1989;11:135-142.
    • (1989) Mol Cell Biochem , vol.11 , pp. 135-142
    • Bielat, K.1    Tritsch, G.L.2
  • 232
    • 0032503692 scopus 로고    scopus 로고
    • Adenosine deaminase and A1 adenosine receptors internalize together following agonist-induced receptor desensitization
    • Saura CA, Mallol J, Canela EI, Lluis C, Franco R. Adenosine deaminase and A1 adenosine receptors internalize together following agonist-induced receptor desensitization. J Biol Chem 1998;273:17610-17617.
    • (1998) J Biol Chem , vol.273 , pp. 17610-17617
    • Saura, C.A.1    Mallol, J.2    Canela, E.I.3    Lluis, C.4    Franco, R.5
  • 235
    • 0033929572 scopus 로고    scopus 로고
    • Adenosine A(1) receptor in cultured neurons from rat cerebral cortex: Colocalization with adenosine deaminase
    • Ruíz MA, Escriche M, Lluís C, Franco R, Martin M, Andrés A, Ros M. Adenosine A(1) receptor in cultured neurons from rat cerebral cortex: Colocalization with adenosine deaminase. J Neurochem 2000;75:656-664.
    • (2000) J Neurochem , vol.75 , pp. 656-664
    • Ruíz, M.A.1    Escriche, M.2    Lluís, C.3    Franco, R.4    Martin, M.5    Andrés, A.6    Ros, M.7
  • 236
    • 0030045246 scopus 로고    scopus 로고
    • Characterization of adenosine deaminase binding to human CD26 on T cells and its biologic role in immune response
    • Dong RP, Kameoka J, Hegen M, Tanaka T, Xu Y, Schlossman SF, Morimoto C. Characterization of adenosine deaminase binding to human CD26 on T cells and its biologic role in immune response. J Immunol 1996;156:1349-1355.
    • (1996) J Immunol , vol.156 , pp. 1349-1355
    • Dong, R.P.1    Kameoka, J.2    Hegen, M.3    Tanaka, T.4    Xu, Y.5    Schlossman, S.F.6    Morimoto, C.7
  • 238
    • 70349774693 scopus 로고    scopus 로고
    • On the origin of serum CD26 and its altered concentration in cancer patients
    • Cordero OJ, Salgado FJ, Nogueira M. On the origin of serum CD26 and its altered concentration in cancer patients. Cancer Immunol Immunother 2009;58:1723-1747.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1723-1747
    • Cordero, O.J.1    Salgado, F.J.2    Nogueira, M.3
  • 239
    • 70349386312 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 (CD26): Knowing the function before inhibiting the enzyme
    • Matteucci E, Giampietro O. Dipeptidyl peptidase-4 (CD26): Knowing the function before inhibiting the enzyme. Curr Med Chem 2009;16:2943-2951.
    • (2009) Curr Med Chem , vol.16 , pp. 2943-2951
    • Matteucci, E.1    Giampietro, O.2
  • 240
    • 78651325899 scopus 로고    scopus 로고
    • Proline-rich cytokine from neurosecretory granules: A new natural substrate for dipeptidyl peptidase IV
    • Antonyan AA, Sharoyan SG, Mardanyan SS, Galoyan AA. Proline-rich cytokine from neurosecretory granules: A new natural substrate for dipeptidyl peptidase IV. Neurochem Res 2011;36:34-38.
    • (2011) Neurochem Res , vol.36 , pp. 34-38
    • Antonyan, A.A.1    Sharoyan, S.G.2    Mardanyan, S.S.3    Galoyan, A.A.4
  • 241
    • 17144404555 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders
    • Gorrell MD. Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders. Clin Sci (Lond) 2005;198:277-292.
    • (2005) Clin Sci (Lond) , vol.198 , pp. 277-292
    • Gorrell, M.D.1
  • 242
    • 33745045683 scopus 로고    scopus 로고
    • Identification of hydrophobic residues critical for DPP-IV dimerization
    • Chien CH, Tsai CH, Lin CH, Chou CY, Chen X. Identification of hydrophobic residues critical for DPP-IV dimerization. Biochemistry 2006;45:7006-7012.
    • (2006) Biochemistry , vol.45 , pp. 7006-7012
    • Chien, C.H.1    Tsai, C.H.2    Lin, C.H.3    Chou, C.Y.4    Chen, X.5
  • 244
    • 84862758824 scopus 로고    scopus 로고
    • Surface markers of lymphocyte activation and markers of cell proliferation
    • Shipkova M, Wieland E. Surface markers of lymphocyte activation and markers of cell proliferation. Clin Chim Acta 2012;413:1338-1349.
    • (2012) Clin Chim Acta , vol.413 , pp. 1338-1349
    • Shipkova, M.1    Wieland, E.2
  • 245
    • 84872424922 scopus 로고    scopus 로고
    • An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: Potential implications in cardiovascular disease
    • Zhong J, Rao X, Rajagopalan S. An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: Potential implications in cardiovascular disease. Atherosclerosis 2013;226:305-314.
    • (2013) Atherosclerosis , vol.226 , pp. 305-314
    • Zhong, J.1    Rao, X.2    Rajagopalan, S.3
  • 246
    • 0031573556 scopus 로고    scopus 로고
    • Determination of adenosine deaminase binding domain on CD26 and its immunoregulatory effect on T cell activation
    • Dong RP, Tachibana K, Hegen M, Munakata Y, Cho D, Schlossman SF, Marimoto C. Determination of adenosine deaminase binding domain on CD26 and its immunoregulatory effect on T cell activation. J Immunol 1997;159:6070-6076.
    • (1997) J Immunol , vol.159 , pp. 6070-6076
    • Dong, R.P.1    Tachibana, K.2    Hegen, M.3    Munakata, Y.4    Cho, D.5    Schlossman, S.F.6    Marimoto, C.7
  • 247
    • 0034613689 scopus 로고    scopus 로고
    • The binding site of human adenosine deaminase for CD26/Dipeptidyl peptidase IV: The Arg142Gln mutation impairs binding to cd26 but does not cause immune deficiency
    • Richard E, Arredondo-Vega FX, Santisteban I, Kelly SJ, Patel DD, Hershfield MS. The binding site of human adenosine deaminase for CD26/Dipeptidyl peptidase IV: The Arg142Gln mutation impairs binding to cd26 but does not cause immune deficiency. J Exp Med 2000;192:1223-1236.
    • (2000) J Exp Med , vol.192 , pp. 1223-1236
    • Richard, E.1    Arredondo-Vega, F.X.2    Santisteban, I.3    Kelly, S.J.4    Patel, D.D.5    Hershfield, M.S.6
  • 248
    • 0037205466 scopus 로고    scopus 로고
    • Clustered charged amino acids of human adenosine deaminase comprise a functional epitope for binding the adenosine deaminase complexing protein CD26/dipeptidyl peptidase IV
    • Richard E, Alam SM, Arredondo-Vega FX, Patel DD, Hershfield MS. Clustered charged amino acids of human adenosine deaminase comprise a functional epitope for binding the adenosine deaminase complexing protein CD26/dipeptidyl peptidase IV. J Biol Chem 2002;277:19720-19726.
    • (2002) J Biol Chem , vol.277 , pp. 19720-19726
    • Richard, E.1    Alam, S.M.2    Arredondo-Vega, F.X.3    Patel, D.D.4    Hershfield, M.S.5
  • 249
    • 5644261220 scopus 로고    scopus 로고
    • Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface
    • Weihofen WA, Liu J, Reutter W, Saenger W, Fan H. Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface. J Biol Chem 2004;279:43330-43335.
    • (2004) J Biol Chem , vol.279 , pp. 43330-43335
    • Weihofen, W.A.1    Liu, J.2    Reutter, W.3    Saenger, W.4    Fan, H.5
  • 252
    • 84857370202 scopus 로고    scopus 로고
    • Molecular mechanism and structural basis of interaction of dipeptidyl peptidase IV with adenosine deaminase and human immunodeficiency virus type-1 transcription transactivator
    • Fan H, Tansi FL, Weihofen WA, Böttcher C, Hu J, Martinez J, Saenger W, Reutter W. Molecular mechanism and structural basis of interaction of dipeptidyl peptidase IV with adenosine deaminase and human immunodeficiency virus type-1 transcription transactivator. Eur J Cell Biol 2012;91:265-273.
    • (2012) Eur J Cell Biol , vol.91 , pp. 265-273
    • Fan, H.1    Tansi, F.L.2    Weihofen, W.A.3    Böttcher, C.4    Hu, J.5    Martinez, J.6    Saenger, W.7    Reutter, W.8
  • 253
    • 33749871009 scopus 로고    scopus 로고
    • Influence of dipeptidyl peptidase IV on enzymatic properties of adenosine deaminase
    • Sharoyan S, Antonyan A, Mardanyan S, Lupidi G, Cristalli G. Influence of dipeptidyl peptidase IV on enzymatic properties of adenosine deaminase. Acta Biochim Pol 2006;53:539-546.
    • (2006) Acta Biochim Pol , vol.53 , pp. 539-546
    • Sharoyan, S.1    Antonyan, A.2    Mardanyan, S.3    Lupidi, G.4    Cristalli, G.5
  • 254
    • 48649107640 scopus 로고    scopus 로고
    • Conditioning response to granulocyte colony-stimulating factor via the dipeptidyl peptidase IV-adenosine deaminase complex
    • Focosi D, Kast RE, Galimberli S, Petrini M. Conditioning response to granulocyte colony-stimulating factor via the dipeptidyl peptidase IV-adenosine deaminase complex. J Leukoc Biol 2008;84:331-337.
    • (2008) J Leukoc Biol , vol.84 , pp. 331-337
    • Focosi, D.1    Kast, R.E.2    Galimberli, S.3    Petrini, M.4
  • 260
    • 84863724041 scopus 로고    scopus 로고
    • An old enzyme for current needs: Adenosine deaminase and a dendritic cell vaccine for HIV
    • Martínez-Navío JM, Climent N, Gallart T, Lluís C, Franco R. An old enzyme for current needs: Adenosine deaminase and a dendritic cell vaccine for HIV. Immunol Cell Biol 2012;90:594-600.
    • (2012) Immunol Cell Biol , vol.90 , pp. 594-600
    • Martínez-Navío, J.M.1    Climent, N.2    Gallart, T.3    Lluís, C.4    Franco, R.5
  • 261
    • 0038713433 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV overexpression induces up-regulation of E-cadherin and tissue inhibitors of matrix metalloproteinases, resulting in decreased invasive potential in ovarian carcinoma cells
    • Kajiyama H, Kikkawa F, Khin E, Shibata K, Ino K, Mizutani S. Dipeptidyl peptidase IV overexpression induces up-regulation of E-cadherin and tissue inhibitors of matrix metalloproteinases, resulting in decreased invasive potential in ovarian carcinoma cells. Cancer Res 2003;63:2278-2283.
    • (2003) Cancer Res , vol.63 , pp. 2278-2283
    • Kajiyama, H.1    Kikkawa, F.2    Khin, E.3    Shibata, K.4    Ino, K.5    Mizutani, S.6
  • 262
    • 0038118637 scopus 로고    scopus 로고
    • Increased adhesion potency of ovarian carcinoma cells to mesothelial cells by overexpression of dipeptidyl peptidase IV
    • Kikkawa F, Kajiyama H, Ino K, Shibata K, Mizutani S. Increased adhesion potency of ovarian carcinoma cells to mesothelial cells by overexpression of dipeptidyl peptidase IV. Int J Cancer 2003;105:779-783.
    • (2003) Int J Cancer , vol.105 , pp. 779-783
    • Kikkawa, F.1    Kajiyama, H.2    Ino, K.3    Shibata, K.4    Mizutani, S.5
  • 263
    • 33947651048 scopus 로고    scopus 로고
    • CD26/dipeptidyl peptidase IV as a novel therapeutic target for cancer and immune disorders
    • Thompson MA, Ohnuma K, Abe M, Morimoto C, Dang NH. CD26/dipeptidyl peptidase IV as a novel therapeutic target for cancer and immune disorders. Mini Rev Med Chem 2007;7:253-273.
    • (2007) Mini Rev Med Chem , vol.7 , pp. 253-273
    • Thompson, M.A.1    Ohnuma, K.2    Abe, M.3    Morimoto, C.4    Dang, N.H.5
  • 266
    • 33750456993 scopus 로고    scopus 로고
    • CD26, together with cell surface adenosine deaminase, is selectively expressed on ALK-positive, but not on ALK-negative, anaplastic large cell lymphoma and Hodgkin's lymphoma
    • Kameoka J, Ichinohasama R, Inoue H, Yamamoto J, Yokoyama H, Tomiya Y, Yamada M, Ishizawa K, Harigae H, Sawai T, Sasaki T. CD26, together with cell surface adenosine deaminase, is selectively expressed on ALK-positive, but not on ALK-negative, anaplastic large cell lymphoma and Hodgkin's lymphoma. Leuk Lymphoma 2006;47:2181-2188.
    • (2006) Leuk Lymphoma , vol.47 , pp. 2181-2188
    • Kameoka, J.1    Ichinohasama, R.2    Inoue, H.3    Yamamoto, J.4    Yokoyama, H.5    Tomiya, Y.6    Yamada, M.7    Ishizawa, K.8    Harigae, H.9    Sawai, T.10    Sasaki, T.11
  • 267
    • 0030041938 scopus 로고    scopus 로고
    • Adenosine deaminase affects ligand-induced signalling by interacting with cell surface adenosine receptors
    • Ciruela F, Saura C, Canela EI, Mallol J, Lluis C, Franco R. Adenosine deaminase affects ligand-induced signalling by interacting with cell surface adenosine receptors. FEBS Lett 1996;380:219-223.
    • (1996) FEBS Lett , vol.380 , pp. 219-223
    • Ciruela, F.1    Saura, C.2    Canela, E.I.3    Mallol, J.4    Lluis, C.5    Franco, R.6
  • 268
    • 0029892284 scopus 로고    scopus 로고
    • Adenosine deaminase interacts with A1 adenosine receptors in pig brain cortical membranes
    • Saura C, Ciruela F, Casadó V, Canela EI, Mallol J, Lluis C, Franco R. Adenosine deaminase interacts with A1 adenosine receptors in pig brain cortical membranes. J Neurochem 1996;66:1675-1682.
    • (1996) J Neurochem , vol.66 , pp. 1675-1682
    • Saura, C.1    Ciruela, F.2    Casadó, V.3    Canela, E.I.4    Mallol, J.5    Lluis, C.6    Franco, R.7
  • 270
    • 0034746914 scopus 로고    scopus 로고
    • Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells
    • Herrera C, Casadó V, Ciruela F, Schofield P, Mallol J, Lluis C, Franco R. Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells. Mol Pharmacol 2001;59:127-134.
    • (2001) Mol Pharmacol , vol.59 , pp. 127-134
    • Herrera, C.1    Casadó, V.2    Ciruela, F.3    Schofield, P.4    Mallol, J.5    Lluis, C.6    Franco, R.7
  • 272
    • 79951717184 scopus 로고    scopus 로고
    • New insight into A1 adenosine receptors in diabetes treatment
    • Wojcik M, Zieleniak A, Wozniak LA. New insight into A1 adenosine receptors in diabetes treatment. Curr Pharm Dev 2010;16:4237-4242.
    • (2010) Curr Pharm Dev , vol.16 , pp. 4237-4242
    • Wojcik, M.1    Zieleniak, A.2    Wozniak, L.A.3
  • 273
    • 80054872347 scopus 로고    scopus 로고
    • Adenosine A(1) receptors in the central nervous system: Their functions in health and disease, and possible elucidation by PET imaging
    • Paul S, Elsinga PH, Ishiwata K, Dierckx RA, van Waarde A. Adenosine A(1) receptors in the central nervous system: Their functions in health and disease, and possible elucidation by PET imaging. Curr Med Chem 2011;18:4820-4835.
    • (2011) Curr Med Chem , vol.18 , pp. 4820-4835
    • Paul, S.1    Elsinga, P.H.2    Ishiwata, K.3    Dierckx, R.A.4    van Waarde, A.5
  • 274
    • 0028169265 scopus 로고
    • Characterization of the human A1 adenosine receptor gene. Evidence for alternative splicing
    • Ren H, Stiles GL. Characterization of the human A1 adenosine receptor gene. Evidence for alternative splicing. J Biol Chem 1994;269:3104-3110.
    • (1994) J Biol Chem , vol.269 , pp. 3104-3110
    • Ren, H.1    Stiles, G.L.2
  • 275
    • 0029144884 scopus 로고
    • The human A1 adenosine receptor: Ligand binding properties, sites of somatic expression and chromosomal localization
    • Rivkees SA, Lasbury ME, Stiles GS, Henegariu O, Curtis C, Vance G. The human A1 adenosine receptor: Ligand binding properties, sites of somatic expression and chromosomal localization. Endocrine 1995;3:623-629.
    • (1995) Endocrine , vol.3 , pp. 623-629
    • Rivkees, S.A.1    Lasbury, M.E.2    Stiles, G.S.3    Henegariu, O.4    Curtis, C.5    Vance, G.6
  • 281
    • 0034923094 scopus 로고    scopus 로고
    • The role and regulation of adenosine in the central nervous system
    • Dunwiddie TV, Masino SA. The role and regulation of adenosine in the central nervous system. Annu Rev Neurosci 2001;24:31-55.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 31-55
    • Dunwiddie, T.V.1    Masino, S.A.2
  • 282
    • 79956307099 scopus 로고    scopus 로고
    • Astrocyte-derived adenosine and A1 receptor activity contribute to sleep loss-induced deficits in hippocampal synaptic plasticity and memory in mice
    • Florian C, Vecsey CG, Halassa MM, Haydon PG, Abel T. Astrocyte-derived adenosine and A1 receptor activity contribute to sleep loss-induced deficits in hippocampal synaptic plasticity and memory in mice. J Neurosci 2011;31:6956-6962.
    • (2011) J Neurosci , vol.31 , pp. 6956-6962
    • Florian, C.1    Vecsey, C.G.2    Halassa, M.M.3    Haydon, P.G.4    Abel, T.5
  • 283
    • 79953234442 scopus 로고    scopus 로고
    • The role of adenosine in the regulation of the sleep
    • Huang ZL, Urade Y, Hayaishi O. The role of adenosine in the regulation of the sleep. Curr Top Med Chem 2011;11:1047-1057.
    • (2011) Curr Top Med Chem , vol.11 , pp. 1047-1057
    • Huang, Z.L.1    Urade, Y.2    Hayaishi, O.3
  • 284
    • 0029070924 scopus 로고
    • Essential role of adenosine, adenosine A1 receptors, and ATP-sensitive K+ channels in cerebral ischemic preconditioning
    • Heurteaux C, Lauritzen I, Widmann C, Lazdunski M. Essential role of adenosine, adenosine A1 receptors, and ATP-sensitive K+ channels in cerebral ischemic preconditioning. Proc Natl Acad Sci USA 1995;92:4666-4670.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4666-4670
    • Heurteaux, C.1    Lauritzen, I.2    Widmann, C.3    Lazdunski, M.4
  • 285
    • 0034859710 scopus 로고    scopus 로고
    • Renal effects of adenosine A1-receptor antagonists in congestive heart failure
    • Gottlieb SS. Renal effects of adenosine A1-receptor antagonists in congestive heart failure. Drugs 2001;61:1387-1393.
    • (2001) Drugs , vol.61 , pp. 1387-1393
    • Gottlieb, S.S.1
  • 287
    • 58149391402 scopus 로고    scopus 로고
    • A1 adenosine receptor agonists and their potential therapeutic applications
    • Elzein E, Zablocki J. A1 adenosine receptor agonists and their potential therapeutic applications. Expert Opin Investig Drugs 2008;17:1901-1910.
    • (2008) Expert Opin Investig Drugs , vol.17 , pp. 1901-1910
    • Elzein, E.1    Zablocki, J.2
  • 288
    • 70349306892 scopus 로고    scopus 로고
    • A1 adenosine receptor antagonists, agonists and allosteric enhancers
    • Kiesman WF, Elzein E, Zablocki J. A1 adenosine receptor antagonists, agonists and allosteric enhancers. Handb Exp Pharmacol 2009;193:25-58.
    • (2009) Handb Exp Pharmacol , vol.193 , pp. 25-58
    • Kiesman, W.F.1    Elzein, E.2    Zablocki, J.3
  • 289
    • 62849103373 scopus 로고    scopus 로고
    • The adenosine A1 receptor and its ligands
    • Nell PG, Albrecht-Kupper B. The adenosine A1 receptor and its ligands. Prog Med Chem 2009;47:163-201.
    • (2009) Prog Med Chem , vol.47 , pp. 163-201
    • Nell, P.G.1    Albrecht-Kupper, B.2
  • 291
    • 13744250069 scopus 로고    scopus 로고
    • A1 antagonism in asthma: Better than coffee
    • Tiller SL, Boucher RC. A1 antagonism in asthma: Better than coffee? J Clin Invest 2005;115:13-16.
    • (2005) J Clin Invest , vol.115 , pp. 13-16
    • Tiller, S.L.1    Boucher, R.C.2
  • 292
    • 77955660757 scopus 로고    scopus 로고
    • Adenosine A1 receptor antagonists in clinical research and development
    • Hocher B. Adenosine A1 receptor antagonists in clinical research and development. Kidney Int 2010;78:438-445.
    • (2010) Kidney Int , vol.78 , pp. 438-445
    • Hocher, B.1
  • 293
    • 84880131404 scopus 로고    scopus 로고
    • Chronic treatment with DPCPX, an adenosine A(1) antagonist, worsens long-term memory
    • Vollert C, Forkuo GS, Bond RA, Eriksen JL. Chronic treatment with DPCPX, an adenosine A(1) antagonist, worsens long-term memory. Neurosci Lett 2013;548:296-300.
    • (2013) Neurosci Lett , vol.548 , pp. 296-300
    • Vollert, C.1    Forkuo, G.S.2    Bond, R.A.3    Eriksen, J.L.4
  • 295
    • 0034064253 scopus 로고    scopus 로고
    • 3]GABA release from rat hippocampal nerve terminals
    • 3]GABA release from rat hippocampal nerve terminals. Neuropharmacology 2000;39:1156-1167.
    • (2000) Neuropharmacology , vol.39 , pp. 1156-1167
    • Cunha, R.A.1    Ribeiro, J.A.2
  • 296
    • 47349125085 scopus 로고    scopus 로고
    • Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders
    • Cunha RA, Ferré S, Vaugeois JM, Chen JF. Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders. Curr Pharm Des 2008;14:1512-1524.
    • (2008) Curr Pharm Des , vol.14 , pp. 1512-1524
    • Cunha, R.A.1    Ferré, S.2    Vaugeois, J.M.3    Chen, J.F.4
  • 297
    • 0033408368 scopus 로고    scopus 로고
    • Central adenosine A(2A) receptors. An overview
    • Moreau JL, Huber G. Central adenosine A(2A) receptors. An overview. Brain Res Rev 1999;31:65.82.
    • (1999) Brain Res Rev , vol.31 , pp. 6582
    • Moreau, J.L.1    Huber, G.2
  • 298
  • 300
    • 77953488397 scopus 로고    scopus 로고
    • A2A receptor ligands: Past, present and future trends
    • Clementina M, Giuseppe S. A2A receptor ligands: Past, present and future trends. Curr Top Med Chem 2010;10:902-922.
    • (2010) Curr Top Med Chem , vol.10 , pp. 902-922
    • Clementina, M.1    Giuseppe, S.2
  • 301
    • 84859105191 scopus 로고    scopus 로고
    • The role of the A2A receptor agonist, regadenoson, in modulating hepatic artery flow in the porcine small-for-size liver graft
    • Zhu X, Shiba H, Fung JJ, Wang LF, Arakawa Y, Irefin S, Demetris AJ, Kelly DM. The role of the A2A receptor agonist, regadenoson, in modulating hepatic artery flow in the porcine small-for-size liver graft. J Surg Res 2012;174:e37-45.
    • (2012) J Surg Res , vol.174 , pp. e37-e45
    • Zhu, X.1    Shiba, H.2    Fung, J.J.3    Wang, L.F.4    Arakawa, Y.5    Irefin, S.6    Demetris, A.J.7    Kelly, D.M.8
  • 302
    • 78649740959 scopus 로고    scopus 로고
    • Quantification of indirect pathway inhibition by the adenosine A2A antagonist SYN 115 in Parkinson disease
    • Black KJ, Koller JM, Campbell MC, Gusnard DA Bandak SI. Quantification of indirect pathway inhibition by the adenosine A2A antagonist SYN 115 in Parkinson disease. J Neurosci 2010;30:16284-16292.
    • (2010) J Neurosci , vol.30 , pp. 16284-16292
    • Black, K.J.1    Koller, J.M.2    Campbell, M.C.3    Gusnard, D.A.4    Bandak, S.I.5
  • 303
    • 73449102471 scopus 로고    scopus 로고
    • A new ethyl adenine antagonist of adenosine A(2A) receptors: Behavioral and biochemical characterization as an anti-Parkinsonian drug
    • Pinna A, Tronci E, Schintu N, Simola N, Volpini R, Pontis S, Cristalli G, Morelli M. A new ethyl adenine antagonist of adenosine A(2A) receptors: Behavioral and biochemical characterization as an anti-Parkinsonian drug. Neuropharmacology 2010;58:613-623.
    • (2010) Neuropharmacology , vol.58 , pp. 613-623
    • Pinna, A.1    Tronci, E.2    Schintu, N.3    Simola, N.4    Volpini, R.5    Pontis, S.6    Cristalli, G.7    Morelli, M.8
  • 304
    • 80054959849 scopus 로고    scopus 로고
    • Adenosine A(2A) receptor antagonists and Parkinson's disease
    • Shook BC, Jackson PF. Adenosine A(2A) receptor antagonists and Parkinson's disease. ACS Chem Neurosci 2011;2:555-567.
    • (2011) ACS Chem Neurosci , vol.2 , pp. 555-567
    • Shook, B.C.1    Jackson, P.F.2
  • 305
    • 80055002811 scopus 로고    scopus 로고
    • Past, present and future of A(2A) adenosine receptor antagonists in the therapy of Parkinson's disease
    • Armentero MT, Pinna A, Ferré, S, Lanciego JL, Müller CE, Franco R. Past, present and future of A(2A) adenosine receptor antagonists in the therapy of Parkinson's disease. Pharmacol Ther 2011;132:280-299.
    • (2011) Pharmacol Ther , vol.132 , pp. 280-299
    • Armentero, M.T.1    Pinna, A.2    Ferré, S.3    Lanciego, J.L.4    Müller, C.E.5    Franco, R.6
  • 306
    • 84865640480 scopus 로고    scopus 로고
    • Adenosine A2A antagonists in Parkinson's disease: What's next
    • Hickey P, Stacy M. Adenosine A2A antagonists in Parkinson's disease: What's next? Curr Neurol Neurosci Rep 2012;12:376-385.
    • (2012) Curr Neurol Neurosci Rep , vol.12 , pp. 376-385
    • Hickey, P.1    Stacy, M.2
  • 307
    • 82355172005 scopus 로고    scopus 로고
    • Adenosine A2A-receptor antagonism and pathophysiology of Parkinson's disease and drug-induced movement disorders
    • Kulisevsky J, Poyurovsky M. Adenosine A2A-receptor antagonism and pathophysiology of Parkinson's disease and drug-induced movement disorders. Eur Neurol 2012;67:4-11.
    • (2012) Eur Neurol , vol.67 , pp. 4-11
    • Kulisevsky, J.1    Poyurovsky, M.2
  • 308
    • 84869017768 scopus 로고    scopus 로고
    • Potential therapeutic relevance of adenosine A2B and A2A receptors in the central nervous system
    • Popoli P, Pepponi R. Potential therapeutic relevance of adenosine A2B and A2A receptors in the central nervous system. CNS Neurol Disord Drug Targets 2012;11:664-674.
    • (2012) CNS Neurol Disord Drug Targets , vol.11 , pp. 664-674
    • Popoli, P.1    Pepponi, R.2
  • 310
    • 84880337603 scopus 로고    scopus 로고
    • Suitability of the adenosine antagonist istradefylline for the treatment of Parkinson's disease: Pharmacokinetic and clinical considerations
    • Muller T. Suitability of the adenosine antagonist istradefylline for the treatment of Parkinson's disease: Pharmacokinetic and clinical considerations. Expert Opin Drug Metab Toxicol 2013;9:1015-1024.
    • (2013) Expert Opin Drug Metab Toxicol , vol.9 , pp. 1015-1024
    • Muller, T.1
  • 311
    • 79952027612 scopus 로고    scopus 로고
    • Recent developments in adenosine receptor ligands and their potential as novel drugs
    • Müller CE, Jacobson KA. Recent developments in adenosine receptor ligands and their potential as novel drugs. Biochim Biophys Acta 2011;1808:1290-1308.
    • (2011) Biochim Biophys Acta , vol.1808 , pp. 1290-1308
    • Müller, C.E.1    Jacobson, K.A.2
  • 315
    • 25444452169 scopus 로고    scopus 로고
    • Adenosine inhibits PDGF-induced growth of human glomerular mesanglial cells via A2B receptors
    • Dubey RK, Gillespie DG, Mi Z, Jackson EK. Adenosine inhibits PDGF-induced growth of human glomerular mesanglial cells via A2B receptors. Hypertension 2005;46:628-634.
    • (2005) Hypertension , vol.46 , pp. 628-634
    • Dubey, R.K.1    Gillespie, D.G.2    Mi, Z.3    Jackson, E.K.4
  • 319
    • 79955945044 scopus 로고    scopus 로고
    • Role of adenosine A(2B) receptors in inflammation
    • Feoktistov I, Biaggioni I. Role of adenosine A(2B) receptors in inflammation. Adv Pharmacol 2011;61:115-144.
    • (2011) Adv Pharmacol , vol.61 , pp. 115-144
    • Feoktistov, I.1    Biaggioni, I.2
  • 320
    • 79960373063 scopus 로고    scopus 로고
    • The four cysteine residues in the second extracellular loop of the human adenosine A2B receptor: Role in ligand binding and receptor function
    • Schiedel AC, Hinz S, Thimm D, Sherbiny F, Borrmann T, Maass A, Müller CE. The four cysteine residues in the second extracellular loop of the human adenosine A2B receptor: Role in ligand binding and receptor function. Biochem Pharmacol 2011;82:389-399.
    • (2011) Biochem Pharmacol , vol.82 , pp. 389-399
    • Schiedel, A.C.1    Hinz, S.2    Thimm, D.3    Sherbiny, F.4    Borrmann, T.5    Maass, A.6    Müller, C.E.7
  • 325
    • 0033944602 scopus 로고    scopus 로고
    • The heat shock cognate protein hsc73 assembles with A(1) adenosine receptors to form functional modules in the cell membrane
    • Sarrió S, Casadó V, Escriche M, Ciruela F, Mallol J, Canela EI, Lluis C, Franco R. The heat shock cognate protein hsc73 assembles with A(1) adenosine receptors to form functional modules in the cell membrane. Mol Cell Biol 2000;20:5164-5174.
    • (2000) Mol Cell Biol , vol.20 , pp. 5164-5174
    • Sarrió, S.1    Casadó, V.2    Escriche, M.3    Ciruela, F.4    Mallol, J.5    Canela, E.I.6    Lluis, C.7    Franco, R.8
  • 326
    • 13444280482 scopus 로고    scopus 로고
    • Modulating effect of adenosine deaminase on function of adenosine A1 receptors
    • Sun WC, Cao Y, Jin L, Wang LZ, Meng F, Zhu XZ. Modulating effect of adenosine deaminase on function of adenosine A1 receptors. Acta Pharmacol Sin 2005;26:160-165.
    • (2005) Acta Pharmacol Sin , vol.26 , pp. 160-165
    • Sun, W.C.1    Cao, Y.2    Jin, L.3    Wang, L.Z.4    Meng, F.5    Zhu, X.Z.6
  • 330
    • 84875700546 scopus 로고    scopus 로고
    • Adenosine receptors as drug targets-What are the challenges
    • Chen JF, Eltzschig HK, Fredholm BB. Adenosine receptors as drug targets-What are the challenges? Nat Rev Drug Discov 2013;12:265-286.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 265-286
    • Chen, J.F.1    Eltzschig, H.K.2    Fredholm, B.B.3
  • 331
    • 84893492313 scopus 로고    scopus 로고
    • Adenosine receptors: New therapeutic targets for inflammation in diabetic nephropathy
    • Elsherbiny NM, Al-Gayyar MM. Adenosine receptors: New therapeutic targets for inflammation in diabetic nephropathy. Inflamm Allergy Drug Targets 2013;12:153-161.
    • (2013) Inflamm Allergy Drug Targets , vol.12 , pp. 153-161
    • Elsherbiny, N.M.1    Al-Gayyar, M.M.2
  • 332
    • 84883818486 scopus 로고    scopus 로고
    • Cardiovascular adenosine receptors: Expression, actions and interactions
    • Headrick JP, Ashton KJ, Rose'meyer RB, Peart JN. Cardiovascular adenosine receptors: Expression, actions and interactions. Pharmacol Ther 2013;140:92-111.
    • (2013) Pharmacol Ther , vol.140 , pp. 92-111
    • Headrick, J.P.1    Ashton, K.J.2    Rose'meyer, R.B.3    Peart, J.N.4
  • 333
    • 0036258990 scopus 로고    scopus 로고
    • G protein-coupled receptor allosterism and complexing
    • Christopoulos A, Kenakin T. G protein-coupled receptor allosterism and complexing. Pharmacol Rev 2002;54:323-374.
    • (2002) Pharmacol Rev , vol.54 , pp. 323-374
    • Christopoulos, A.1    Kenakin, T.2
  • 334
    • 33645360875 scopus 로고    scopus 로고
    • Allosterism in membrane receptors
    • Gao ZG, Jacobson KA. Allosterism in membrane receptors. Drug Discov Today 2006;11:191-202.
    • (2006) Drug Discov Today , vol.11 , pp. 191-202
    • Gao, Z.G.1    Jacobson, K.A.2
  • 337
    • 58149193205 scopus 로고    scopus 로고
    • Allosteric modulation of GPCRs: A novel approach for the treatment of CNS disorders
    • Conn JP, Christopoulos A, Linsley CW. Allosteric modulation of GPCRs: A novel approach for the treatment of CNS disorders. Nature Rev Drug Discovery 2009;8:41-54.
    • (2009) Nature Rev Drug Discovery , vol.8 , pp. 41-54
    • Conn, J.P.1    Christopoulos, A.2    Linsley, C.W.3
  • 338
    • 77951985712 scopus 로고    scopus 로고
    • Allosteric ligands for G protein-coupled receptors: A novel strategy with attractive therapeutic opportunities
    • De
    • De Amici M, Dallanoce C, Holzgrabe U, Tränkle C, Mohr K. Allosteric ligands for G protein-coupled receptors: A novel strategy with attractive therapeutic opportunities. Med Res Rev 2010;30:463-549.
    • (2010) Med Res Rev , vol.30 , pp. 463-549
    • Amici, M.1    Dallanoce, C.2    Holzgrabe, U.3    Tränkle, C.4    Mohr, K.5
  • 339
    • 78650147139 scopus 로고    scopus 로고
    • Allostery at G protein-coupled receptor homo- and heteromers: Uncharted pharmacological landscapes
    • Smith NJ, Milligan G. Allostery at G protein-coupled receptor homo- and heteromers: Uncharted pharmacological landscapes. Pharmacol Rev 2010;62:701-725.
    • (2010) Pharmacol Rev , vol.62 , pp. 701-725
    • Smith, N.J.1    Milligan, G.2
  • 340
    • 84857375139 scopus 로고    scopus 로고
    • Allosteric modulation of seven transmembrane spanning receptors: Theory, practice, and opportunities for central nervous system drug discovery
    • Melancon BJ, Hopkins CR, Wood MR, Emmitte KA, Niswender CM, Christopoulos A, Conn PJ, Lindsley CW. Allosteric modulation of seven transmembrane spanning receptors: Theory, practice, and opportunities for central nervous system drug discovery. J Med Chem 2012;55:1445-1464.
    • (2012) J Med Chem , vol.55 , pp. 1445-1464
    • Melancon, B.J.1    Hopkins, C.R.2    Wood, M.R.3    Emmitte, K.A.4    Niswender, C.M.5    Christopoulos, A.6    Conn, P.J.7    Lindsley, C.W.8
  • 341
    • 0036490942 scopus 로고    scopus 로고
    • Allosteric binding sites on cell-surface receptors. Novel targets for drug discovery
    • Christopoulos A. Allosteric binding sites on cell-surface receptors. Novel targets for drug discovery. Nat Rev Drug Discov 2002;1:198-210.
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 198-210
    • Christopoulos, A.1
  • 342
    • 0141869933 scopus 로고    scopus 로고
    • Allosteric modulators of G-protein-coupled receptors
    • May LT, Christopoulos A. Allosteric modulators of G-protein-coupled receptors. Curr Opinion Pharmacol 2003;3:551-556.
    • (2003) Curr Opinion Pharmacol , vol.3 , pp. 551-556
    • May, L.T.1    Christopoulos, A.2
  • 343
    • 0025603686 scopus 로고
    • Allosteric enhancement of adenosine A1 receptor binding and function by 2-amino-3-benzoylthiophenes
    • Bruns RF, Fergus JH. Allosteric enhancement of adenosine A1 receptor binding and function by 2-amino-3-benzoylthiophenes. Mol Pharmacol 1990;38:939-949.
    • (1990) Mol Pharmacol , vol.38 , pp. 939-949
    • Bruns, R.F.1    Fergus, J.H.2
  • 345
    • 32844467152 scopus 로고    scopus 로고
    • 2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers
    • Nikolakopoulos G, Figler H, Linden J, Scammells PJ. 2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers. Bioorg Med Chem 2006;14:2358-2365.
    • (2006) Bioorg Med Chem , vol.14 , pp. 2358-2365
    • Nikolakopoulos, G.1    Figler, H.2    Linden, J.3    Scammells, P.J.4
  • 346
    • 67650756920 scopus 로고    scopus 로고
    • Allosteric modulators of the adenosine A1 receptor: Synthesis and pharmacological evaluation of 4-substituted 2-amnio-3-benzoylthiophenes
    • Aurelio L, Valant C, Flynn BL, Sexton PM, Christopoulos A, Scamells PJ. Allosteric modulators of the adenosine A1 receptor: Synthesis and pharmacological evaluation of 4-substituted 2-amnio-3-benzoylthiophenes. J Med Chem 2009;52:4543-4547.
    • (2009) J Med Chem , vol.52 , pp. 4543-4547
    • Aurelio, L.1    Valant, C.2    Flynn, B.L.3    Sexton, P.M.4    Christopoulos, A.5    Scamells, P.J.6
  • 348
    • 84863416234 scopus 로고    scopus 로고
    • Synthesis and characterization of novel 2-amino-3benzoylthiophene derivatives as biased allosteric agonists and modulators of the adenosine A1 receptor
    • Valant C, Aurelio L, Devine SM, Ashton TD, White JM, Sexton PM, Christopoulos A, Scammells PJ. Synthesis and characterization of novel 2-amino-3benzoylthiophene derivatives as biased allosteric agonists and modulators of the adenosine A1 receptor. J Med Chem 2012;55:2367-2375.
    • (2012) J Med Chem , vol.55 , pp. 2367-2375
    • Valant, C.1    Aurelio, L.2    Devine, S.M.3    Ashton, T.D.4    White, J.M.5    Sexton, P.M.6    Christopoulos, A.7    Scammells, P.J.8
  • 349
    • 79953224436 scopus 로고    scopus 로고
    • Allosteric modulation of adenosine receptors
    • Goblyos A, Ijzerman AP. Allosteric modulation of adenosine receptors. Biochim Biophys Acta 2011;1808:1309-1318.
    • (2011) Biochim Biophys Acta , vol.1808 , pp. 1309-1318
    • Goblyos, A.1    Ijzerman, A.P.2
  • 350
    • 0034284626 scopus 로고    scopus 로고
    • Allosteric modulation of A(2A) adenosine receptors by amiloride analogues and sodium ions
    • Gao ZG, Ijzerman AP. Allosteric modulation of A(2A) adenosine receptors by amiloride analogues and sodium ions. Biochem Pharmacol 2000;60:669-676.
    • (2000) Biochem Pharmacol , vol.60 , pp. 669-676
    • Gao, Z.G.1    Ijzerman, A.P.2
  • 351
    • 47349125847 scopus 로고    scopus 로고
    • A2A adenosine receptor and its modulators: Overview on a druggable GPCR and on structure-activity relationship analysis and binding requirements of agonists and antagonists
    • Cristalli G, Lambertucci C, Marucci G, Volpini R, Dal Ben D. A2A adenosine receptor and its modulators: Overview on a druggable GPCR and on structure-activity relationship analysis and binding requirements of agonists and antagonists. Curr Pharm Des 2008;14:1525-1552.
    • (2008) Curr Pharm Des , vol.14 , pp. 1525-1552
    • Cristalli, G.1    Lambertucci, C.2    Marucci, G.3    Volpini, R.4    Dal Ben, D.5
  • 352
    • 67249089932 scopus 로고    scopus 로고
    • Reduced ligand affinity leads to an impaired function of the adenosine A2A receptor of human granulocytes in sepsis
    • Kreth S, Kaufmann I, Kedderose C, Luchting B, Thiel M. Reduced ligand affinity leads to an impaired function of the adenosine A2A receptor of human granulocytes in sepsis. J Cell Mol Med 2009;13:985-994.
    • (2009) J Cell Mol Med , vol.13 , pp. 985-994
    • Kreth, S.1    Kaufmann, I.2    Kedderose, C.3    Luchting, B.4    Thiel, M.5
  • 357
    • 34047161070 scopus 로고    scopus 로고
    • Functions, dysfunctions and possible therapeutic relevance of adenosine A2A receptors in Huntington's disease
    • Popoli P, Blum D, Martire A, Ledent C, Ceruti S, Abbracchio MP. Functions, dysfunctions and possible therapeutic relevance of adenosine A2A receptors in Huntington's disease. Prog Neurobiol 2007;81:331-348.
    • (2007) Prog Neurobiol , vol.81 , pp. 331-348
    • Popoli, P.1    Blum, D.2    Martire, A.3    Ledent, C.4    Ceruti, S.5    Abbracchio, M.P.6
  • 359
    • 70349331090 scopus 로고    scopus 로고
    • Adenosine receptors and neurological disease: Neuroprotection and neurodegeneration
    • Stone TW, Ceruti S, Abbracchio MP. Adenosine receptors and neurological disease: Neuroprotection and neurodegeneration. Handb Exp Pharmacol 2009;193:535-587.
    • (2009) Handb Exp Pharmacol , vol.193 , pp. 535-587
    • Stone, T.W.1    Ceruti, S.2    Abbracchio, M.P.3
  • 360
    • 34547434085 scopus 로고    scopus 로고
    • Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit
    • Ernst OP, Gramse V, Kolbe M, Hofmann KP, Heck M. Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit. Proc Natl Acad Sci USA 2007;104:10859-10864.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 10859-10864
    • Ernst, O.P.1    Gramse, V.2    Kolbe, M.3    Hofmann, K.P.4    Heck, M.5
  • 361
  • 363
    • 70350381113 scopus 로고    scopus 로고
    • Purification and functional reconstitution of monomeric mu-opioid receptors: Allosteric modulation of agonist binding by Gi2
    • Kuszak AJ, Pitchiaya Anand JP, Mosberg HI, Walter NG, Sunahara RK. Purification and functional reconstitution of monomeric mu-opioid receptors: Allosteric modulation of agonist binding by Gi2. J Biol Chem 2009;284:26732-26741.
    • (2009) J Biol Chem , vol.284 , pp. 26732-26741
    • Kuszak, A.J.1    Pitchiaya Anand, J.P.2    Mosberg, H.I.3    Walter, N.G.4    Sunahara, R.K.5
  • 365
  • 369
    • 72449211146 scopus 로고    scopus 로고
    • Oligomerization of G-protein-coupled receptors: A reality
    • Ferré S, Franco R. Oligomerization of G-protein-coupled receptors: A reality. Curr Opin Pharmacol 2010;10:1-5.
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 1-5
    • Ferré, S.1    Franco, R.2
  • 370
    • 72449147362 scopus 로고    scopus 로고
    • Dimerization in GPCR mobility and signalling
    • Lohse MJ. Dimerization in GPCR mobility and signalling. Curr Opin Pharmacol 2010;10:53-58.
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 53-58
    • Lohse, M.J.1
  • 371
    • 79953194763 scopus 로고    scopus 로고
    • Dimerization and ligand binding affect the structure network of A2A adenosine receptor
    • Fanelli F, Felline A. Dimerization and ligand binding affect the structure network of A2A adenosine receptor. Biochim Biophys Acta 2011;1808:1256-1266.
    • (2011) Biochim Biophys Acta , vol.1808 , pp. 1256-1266
    • Fanelli, F.1    Felline, A.2
  • 372
    • 78751700316 scopus 로고    scopus 로고
    • Organization of higher order oligomers of the serotonin 1A receptor explored utilizing homo-FRET in live cells
    • Ganguly S, Clayton AHA, Chattopadhyay A. Organization of higher order oligomers of the serotonin 1A receptor explored utilizing homo-FRET in live cells. Biophys J 2011;100:361-368.
    • (2011) Biophys J , vol.100 , pp. 361-368
    • Ganguly, S.1    Clayton, A.H.A.2    Chattopadhyay, A.3
  • 373
    • 79551485761 scopus 로고    scopus 로고
    • Exploring a role for heteromerization in GPCR signalling specificity
    • Rozenfeld R, Devi LA. Exploring a role for heteromerization in GPCR signalling specificity. Biochem J 2011;433:11-18.
    • (2011) Biochem J , vol.433 , pp. 11-18
    • Rozenfeld, R.1    Devi, L.A.2
  • 374
    • 80053487319 scopus 로고    scopus 로고
    • Oligomerization of G protein-coupled receptors. Computational methods
    • Selent J, Kaczor AA. Oligomerization of G protein-coupled receptors. Computational methods. Curr Med Chem 2011;18:4588-4605.
    • (2011) Curr Med Chem , vol.18 , pp. 4588-4605
    • Selent, J.1    Kaczor, A.A.2
  • 376
    • 84871353890 scopus 로고    scopus 로고
    • Receptor oligomerization in family B1 of G-protein-coupled receptors: Focus on BRET investigations and the link between GPCR oligomerization and binding cooperativity
    • Roed SN, Orgaard A, Jorgensen R, De Meyts P. Receptor oligomerization in family B1 of G-protein-coupled receptors: Focus on BRET investigations and the link between GPCR oligomerization and binding cooperativity. Front Endocrinol 2012;3:62.
    • (2012) Front Endocrinol , vol.3 , pp. 62
    • Roed, S.N.1    Orgaard, A.2    Jorgensen, R.3    De Meyts, P.4
  • 377
    • 84863615246 scopus 로고    scopus 로고
    • 2C) receptor revealed by fluorescence correlation spectroscopy with photon counting histogram analysis. Evidence for homodimers without monomers or tetramers
    • 2C) receptor revealed by fluorescence correlation spectroscopy with photon counting histogram analysis. Evidence for homodimers without monomers or tetramers. J Biol Chem 2012;287:23604-23614.
    • (2012) J Biol Chem , vol.287 , pp. 23604-23614
    • Herrick-Davis, K.1    Grinde, E.2    Lindsley, T.3    Cowan, A.4    Mazurkiewicz, J.E.5
  • 378
    • 84884683292 scopus 로고    scopus 로고
    • Fluorescence correlation spectroscopy analysis of serotonin, adrenergic, muscarinic and dopamine receptor dimerization: The oligomer number puzzle
    • Herrick-Davis K, Grinde E, Cowan A, Mazurkiewicz JE. Fluorescence correlation spectroscopy analysis of serotonin, adrenergic, muscarinic and dopamine receptor dimerization: The oligomer number puzzle. Mol Pharmacol 2013;84:630-642.
    • (2013) Mol Pharmacol , vol.84 , pp. 630-642
    • Herrick-Davis, K.1    Grinde, E.2    Cowan, A.3    Mazurkiewicz, J.E.4
  • 382
    • 20544449873 scopus 로고    scopus 로고
    • Principles: A model for the allosteric interactions between ligand binding sites within a dimeric GPCR
    • Durroux T. Principles: A model for the allosteric interactions between ligand binding sites within a dimeric GPCR. Trends Pharmacol Sci 2005;26:376-384.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 376-384
    • Durroux, T.1
  • 383
    • 33751195311 scopus 로고    scopus 로고
    • Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding
    • Albizu L, Balestre MN, Breton C, Pin JP, Manning M, Mouillac B, Barberis C, Durroux T. Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding. Mol Pharmacol 2006;70:1783-1791.
    • (2006) Mol Pharmacol , vol.70 , pp. 1783-1791
    • Albizu, L.1    Balestre, M.N.2    Breton, C.3    Pin, J.P.4    Manning, M.5    Mouillac, B.6    Barberis, C.7    Durroux, T.8
  • 384
    • 36249020990 scopus 로고    scopus 로고
    • Old and new ways to calculate the affinity of agonists and antagonists interacting with G-protein-coupled monoméric and dimeric receptors: The receptor-dimer cooperativity index
    • Casadó V, Cortés A, Ciruela F, Mallol J, Ferré S, Lluís C, Canela EI, Franco R. Old and new ways to calculate the affinity of agonists and antagonists interacting with G-protein-coupled monoméric and dimeric receptors: The receptor-dimer cooperativity index. Pharmacol Ther 2007;116:343-354.
    • (2007) Pharmacol Ther , vol.116 , pp. 343-354
    • Casadó, V.1    Cortés, A.2    Ciruela, F.3    Mallol, J.4    Ferré, S.5    Lluís, C.6    Canela, E.I.7    Franco, R.8
  • 386
    • 70350044578 scopus 로고    scopus 로고
    • Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist-antagonist binding modulation
    • Casadó V, Ferrada C, Bonaventura J, Gracia E, Mallol J, Canela EI, Lluís C, Cortés A, Franco R. Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist-antagonist binding modulation. Biochem Pharmacol 2009;78:1456-1463.
    • (2009) Biochem Pharmacol , vol.78 , pp. 1456-1463
    • Casadó, V.1    Ferrada, C.2    Bonaventura, J.3    Gracia, E.4    Mallol, J.5    Canela, E.I.6    Lluís, C.7    Cortés, A.8    Franco, R.9
  • 394
    • 84862324402 scopus 로고    scopus 로고
    • Moonlighting is mainstream: Paradigm adjustment required
    • Copley SD. Moonlighting is mainstream: Paradigm adjustment required. Bioessays 2012;34:578-588.
    • (2012) Bioessays , vol.34 , pp. 578-588
    • Copley, S.D.1
  • 395
  • 396
    • 77950369259 scopus 로고    scopus 로고
    • Moonlighting proteins: An intriguing mode of multitasking
    • Huberts DH, Van der Klei IJ. Moonlighting proteins: An intriguing mode of multitasking. Biochim Biophys Acta 2010;1803:520-525.
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 520-525
    • Huberts, D.H.1    Van der Klei, I.J.2
  • 397
    • 62949096122 scopus 로고    scopus 로고
    • Moonlighting proteins-an update
    • Jeffery CJ. Moonlighting proteins-an update. Mol Bio Syst 2009;5:345-350.
    • (2009) Mol Bio Syst , vol.5 , pp. 345-350
    • Jeffery, C.J.1
  • 398
    • 79959623005 scopus 로고    scopus 로고
    • Moonlighting proteins in neurological disorders
    • Ovadi J. Moonlighting proteins in neurological disorders. IUBMB Life 2011;63:453-456.
    • (2011) IUBMB Life , vol.63 , pp. 453-456
    • Ovadi, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.