Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells

Molecular Pharmacology

Volumn 59, Issue 1, 2001, Pages 127-134

  Herrera, C ^a   Casado V ^a   Ciruela, F ^a   Schofield, P ^b   Mallol, J ^a   Lluis, C ^a   Franco, R ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2B RECEPTOR; ADENOSINE DEAMINASE; CYCLIC AMP; DIPEPTIDYL PEPTIDASE IV; G PROTEIN COUPLED RECEPTOR; PROTEIN; PURINE; ADENOSINE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL SURFACE; CHO CELL; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; ANIMAL; BINDING SITE; BIOSYNTHESIS; CONFOCAL MICROSCOPY; DRUG POTENTIATION; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HAMSTER; LEUKEMIA CELL LINE; METABOLISM; PHYSIOLOGY; SECOND MESSENGER; SERODIAGNOSIS;

ADENOSINE DEAMINASE; ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); ANIMALS; BINDING SITES; CELLS, CULTURED; CHO CELLS; CRICETINAE; CYCLIC AMP; HUMANS; JURKAT CELLS; MICROSCOPY, CONFOCAL; PRECIPITIN TESTS; RECEPTOR, ADENOSINE A2B; RECEPTORS, PURINERGIC P1; SECOND MESSENGER SYSTEMS; T-LYMPHOCYTES; TRANSFECTION;

EID: 0034746914     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.59.1.127     Document Type: Article

References (39)

1. Adenosine acts as an endogenous modulator of IL-2 dependent proliferation of cytotoxic T lymphocytes
2. Effects of extracellular ATP and adenosine on different thymocyte subsets: Possible role of ATP-gated channels and G protein-coupled purinergic receptor
3. Presence of adenosine deaminase on the surface of mononuclear blood cells: Immunochemical localization using light and electron microscopy
4. Separation of leukocytes from blood and bone marrow
5. Solubilization of A1 adenosine receptor from pig brain: Characterization and evidence of the role of the cell membrane on the coexistence of high- and low-affinity states
6. 2B subtype
7. Differential internalisation of mGluR1 splice variants in response to agonists and phorbol esters in permanently transfected BHK cells
8. Adenosine deaminase affects ligand-induced signalling by interacting with cell surface adenosine receptors
9. α with Homer-1a/Vesl-1S increases the cell surface expression of the receptor
10. Binding of adenosine deaminase to the lymphocyte surface via CD26
11. Role of CD26 for CD4 memory T ceil function and activation
12. Characterization of adenosine deaminase binding to human CD26 on T cells and its biologic role in immune response
13. Determination of adenosine deaminase binding domain on CD26 and its immunoregulatory effect on T cell activation
14. Purineric modulation of T-lymphocyte activation: Differential susceptibility of distinct activation steps and correlation with intracellular 3′-5′-cyclic adenosine monophosphate accumulation
15. Cloning of a Grb2 isoform with apoptotic properties
16. Cell surface adenosine deaminase: Much more than an ectoenzyme
17. Enzymatic and extraenzymatic role of ecto-adenosine deaminase in lymphocytes
18. Immunodeficiency diseases caused by adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency
19. 2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion
20. Transfecting mammalian cells: Optimization of critical parameters affecting calcium phosphate precipitate formation
21. Direct association of adenosine deaminase with a T ceil activation antigen CD26
22. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
23. q in human embryonic kidney 293 cells and HMC-1 mast cells
24. Surface expression of adenosine deaminase in mitogen-stimulated lymphocytes
25. Surface adenosine deaminase a novel B-cell marker in chronic lymphocytic leukemia
26. Expression of ecto-adenosine deaminase and CD26 in human T cells triggered by the TCR-CD3 complex: Possible role of adenosine deaminase as costimulatory molecule
27. 2B adenosine receptors in human lymphocytes: Their role in T cell activation
28. The structure and function of CD26 in the T-cell immune response
29. Activation of protein kinase C inhibits prostaglandin- and potentiates adenosine-receptor stimulated accumulation of cyclic AMP in a human T-cell leukemia line
30. Molecular cloning and expression of an adenosine A2b receptor from human brain
31. 2b receptor
32. Roceptors for purines and pyrimidines
33. Adenosine deaminase is a specific partner for the Grb2 isoform Gr3-3
34. SCID: The role of adenosine deaminase deficiency
35. A one-step purification of membrane proteins using a high efficiency immunomatrix
36. A sensitive protein assay using microtiter plates
37. Atomic structure of adenosine deaminase complexed with a transition-state analog: Understanding catalysis and immunodeficiency mutations
38. Adenosine inhibition of lymphocyte mediated cytolysis: Possible role of cyclic adenosine monophosphate
39. 2B adenosine receptor expression in macrophages: A mechanism of macrophage deactivation